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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NFAT5

Z-value: 0.88

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Transcription factors associated with NFAT5

Gene Symbol Gene ID Gene Info
NFAT5
ENSG00000102908.22 NFAT5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFAT5hg38_v1_chr16_+_69566314_695663450.027.2e-01Click!

Activity profile of NFAT5 motif

Sorted Z-values of NFAT5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFAT5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_59630806 9.63 ENST00000342503.8
RTN1
reticulon 1
chr14_-_59630582 9.20 ENST00000395090.5
RTN1
reticulon 1
chr7_+_149872955 8.42 ENST00000421974.7
ENST00000456496.7
ATP6V0E2
ATPase H+ transporting V0 subunit e2
chr10_+_3104676 7.72 ENST00000415005.6
ENST00000468050.1
PFKP
phosphofructokinase, platelet
chr1_-_11654422 6.94 ENST00000354287.5
FBXO2
F-box protein 2
chr11_-_111923722 6.66 ENST00000527950.5
CRYAB
crystallin alpha B
chr13_-_67230377 6.28 ENST00000544246.5
ENST00000377861.4
PCDH9
protocadherin 9
chr14_+_100128573 6.16 ENST00000554695.5
EVL
Enah/Vasp-like
chr13_-_67230313 5.97 ENST00000377865.7
PCDH9
protocadherin 9
chr7_-_101245032 4.96 ENST00000442303.1
FIS1
fission, mitochondrial 1
chr7_-_101245056 4.91 ENST00000223136.5
FIS1
fission, mitochondrial 1
chr10_+_110207587 4.60 ENST00000332674.9
ENST00000453116.5
MXI1
MAX interactor 1, dimerization protein
chr1_-_56579555 4.26 ENST00000371250.4
PLPP3
phospholipid phosphatase 3
chr14_+_91114026 4.01 ENST00000521081.5
ENST00000520328.5
ENST00000524232.5
ENST00000522170.5
ENST00000256324.15
ENST00000519950.5
ENST00000523879.5
ENST00000521077.6
ENST00000518665.6
DGLUCY
D-glutamate cyclase
chr16_+_89921851 3.88 ENST00000554444.5
ENST00000556565.5
TUBB3
tubulin beta 3 class III
chr20_+_34516394 3.82 ENST00000357156.7
ENST00000300469.13
ENST00000374846.3
DYNLRB1
dynein light chain roadblock-type 1
chr3_-_9792404 3.74 ENST00000301964.7
TADA3
transcriptional adaptor 3
chr20_-_23751256 3.63 ENST00000398402.1
CST1
cystatin SN
chr3_+_48989876 3.52 ENST00000343546.8
P4HTM
prolyl 4-hydroxylase, transmembrane
chr22_-_37984534 3.50 ENST00000396884.8
SOX10
SRY-box transcription factor 10
chr20_-_10431922 3.31 ENST00000399054.6
ENST00000609375.1
MKKS
ENSG00000285508.1
McKusick-Kaufman syndrome
novel protein
chr15_+_43593054 3.22 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
CKMT1B
creatine kinase, mitochondrial 1B
chr14_+_91114431 3.16 ENST00000428926.6
ENST00000517362.5
DGLUCY
D-glutamate cyclase
chr14_+_91114364 3.11 ENST00000518868.5
DGLUCY
D-glutamate cyclase
chr14_+_91114388 3.04 ENST00000519019.5
ENST00000523816.5
ENST00000517518.5
DGLUCY
D-glutamate cyclase
chr20_-_23750929 2.90 ENST00000304749.7
CST1
cystatin SN
chr14_+_91114667 2.86 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
DGLUCY
D-glutamate cyclase
chr12_+_101594849 2.33 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
MYBPC1
myosin binding protein C1
chr19_-_54364908 2.31 ENST00000391742.7
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr19_-_54364983 2.27 ENST00000434277.6
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr17_-_42798680 2.26 ENST00000328434.8
COA3
cytochrome c oxidase assembly factor 3
chr11_+_131370478 2.17 ENST00000374791.7
ENST00000683400.1
ENST00000436745.5
NTM
neurotrimin
chr19_+_7534004 2.15 ENST00000221249.10
ENST00000601668.5
ENST00000601001.5
PNPLA6
patatin like phospholipase domain containing 6
chr15_+_48878070 2.15 ENST00000530028.3
ENST00000560490.1
EID1
EP300 interacting inhibitor of differentiation 1
chr22_-_29315656 2.00 ENST00000401450.3
ENST00000216101.7
RASL10A
RAS like family 10 member A
chr5_-_151141631 1.95 ENST00000523714.5
ENST00000521749.5
ANXA6
annexin A6
chr19_+_48325522 1.87 ENST00000594198.1
ENST00000270221.11
ENST00000597279.5
ENST00000593437.1
EMP3
epithelial membrane protein 3
chr19_+_48325323 1.82 ENST00000596315.5
EMP3
epithelial membrane protein 3
chr11_+_131911396 1.79 ENST00000425719.6
ENST00000374784.5
NTM
neurotrimin
chr5_+_140806929 1.79 ENST00000378125.4
ENST00000618834.1
ENST00000530339.2
ENST00000512229.6
ENST00000672575.1
PCDHA4
protocadherin alpha 4
chr5_+_140882116 1.75 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
PCDHA13
protocadherin alpha 13
chr7_+_148133684 1.57 ENST00000628930.2
CNTNAP2
contactin associated protein 2
chr17_+_70075317 1.55 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr16_-_29505820 1.49 ENST00000550665.5
NPIPB12
nuclear pore complex interacting protein family member B12
chr17_+_70075215 1.45 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr19_-_54364863 1.44 ENST00000348231.8
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr9_-_95317671 1.38 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FANCC
FA complementation group C
chr19_-_54364807 1.36 ENST00000474878.5
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr3_+_9793074 1.24 ENST00000397261.8
ENST00000485273.1
ENST00000433034.1
ENST00000397256.5
ARPC4
ARPC4-TTLL3
actin related protein 2/3 complex subunit 4
ARPC4-TTLL3 readthrough
chr19_+_17309531 1.23 ENST00000359866.9
DDA1
DET1 and DDB1 associated 1
chr20_-_45547420 1.18 ENST00000504988.1
EPPIN-WFDC6
EPPIN-WFDC6 readthrough
chr12_+_7155867 1.17 ENST00000535313.2
ENST00000331148.5
CLSTN3
calsyntenin 3
chr22_+_24155797 1.16 ENST00000337989.11
CABIN1
calcineurin binding protein 1
chr20_-_45547648 1.13 ENST00000651288.1
EPPIN-WFDC6
EPPIN-WFDC6 readthrough
chr2_+_130963642 1.13 ENST00000409303.6
ARHGEF4
Rho guanine nucleotide exchange factor 4
chrX_-_57137523 1.11 ENST00000614076.1
ENST00000374906.3
SPIN2A
spindlin family member 2A
chr11_-_8810635 1.09 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENND2B
DENN domain containing 2B
chr14_-_92121902 1.05 ENST00000329559.8
NDUFB1
NADH:ubiquinone oxidoreductase subunit B1
chr7_-_102478895 1.03 ENST00000393794.4
ENST00000292614.9
POLR2J
RNA polymerase II subunit J
chr6_+_101393699 1.01 ENST00000369134.9
ENST00000684068.1
ENST00000683903.1
ENST00000681975.1
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr14_-_102240597 0.94 ENST00000523231.5
ENST00000524370.5
ENST00000517966.5
MOK
MOK protein kinase
chr3_-_41961989 0.92 ENST00000420927.5
ENST00000301831.9
ENST00000414606.1
ULK4
unc-51 like kinase 4
chr5_-_79512794 0.90 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
HOMER1
homer scaffold protein 1
chr19_+_859654 0.89 ENST00000592860.2
ENST00000327726.11
CFD
complement factor D
chr1_-_201377652 0.89 ENST00000455702.6
ENST00000367320.6
ENST00000421663.6
ENST00000412633.3
ENST00000367318.10
ENST00000422165.6
ENST00000656932.1
ENST00000438742.6
ENST00000367322.6
ENST00000458432.6
ENST00000509001.5
ENST00000660295.1
TNNT2
troponin T2, cardiac type
chr10_-_133308844 0.88 ENST00000682905.1
ENST00000682515.1
ENST00000683612.1
ENST00000252936.8
ENST00000417178.7
ENST00000682161.1
ENST00000683014.1
ENST00000683060.1
ENST00000683383.1
TUBGCP2
tubulin gamma complex associated protein 2
chr1_+_116754422 0.71 ENST00000369478.4
ENST00000369477.1
CD2
CD2 molecule
chr3_+_63819341 0.66 ENST00000647022.1
C3orf49
chromosome 3 open reading frame 49
chr1_+_53894181 0.64 ENST00000361921.8
ENST00000322679.10
ENST00000613679.4
ENST00000617230.2
ENST00000610607.4
ENST00000532493.5
ENST00000525202.5
ENST00000524406.5
ENST00000388876.3
DIO1
iodothyronine deiodinase 1
chrX_+_48897900 0.64 ENST00000376566.8
ENST00000376563.5
PQBP1
polyglutamine binding protein 1
chr2_+_48568981 0.63 ENST00000394754.5
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr19_+_3178756 0.59 ENST00000246115.5
S1PR4
sphingosine-1-phosphate receptor 4
chr1_-_173824856 0.59 ENST00000682279.1
CENPL
centromere protein L
chr1_-_31919368 0.56 ENST00000457805.6
ENST00000602725.5
ENST00000679970.1
PTP4A2
ENSG00000288678.1
protein tyrosine phosphatase 4A2
novel protein
chrX_+_30235894 0.54 ENST00000620842.1
MAGEB3
MAGE family member B3
chr1_-_114757971 0.54 ENST00000261443.9
ENST00000534699.5
ENST00000339438.10
ENST00000358528.9
ENST00000529046.5
ENST00000525970.5
ENST00000369530.5
ENST00000530886.5
ENST00000610726.4
CSDE1
cold shock domain containing E1
chr7_+_1086800 0.50 ENST00000413368.5
ENST00000397092.5
ENST00000297469.3
GPER1
G protein-coupled estrogen receptor 1
chr3_+_69763726 0.50 ENST00000448226.9
MITF
melanocyte inducing transcription factor
chr17_-_48530910 0.49 ENST00000577092.1
ENST00000239174.7
HOXB1
homeobox B1
chrX_+_83861126 0.49 ENST00000621735.4
ENST00000329312.5
CYLC1
cylicin 1
chr3_+_40505992 0.47 ENST00000420891.5
ENST00000314529.10
ENST00000418905.1
ZNF620
zinc finger protein 620
chr20_-_45547752 0.47 ENST00000409554.1
EPPIN
epididymal peptidase inhibitor
chr4_-_75940239 0.46 ENST00000505594.1
NAAA
N-acylethanolamine acid amidase
chr19_+_49496424 0.42 ENST00000596873.1
ENST00000594493.1
ENST00000270625.7
ENST00000599561.1
RPS11
ribosomal protein S11
chr14_-_25010604 0.42 ENST00000550887.5
STXBP6
syntaxin binding protein 6
chr3_+_9792495 0.39 ENST00000498623.6
ARPC4
actin related protein 2/3 complex subunit 4
chr2_-_55296361 0.37 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr1_+_159204860 0.37 ENST00000368122.4
ENST00000368121.6
ACKR1
atypical chemokine receptor 1 (Duffy blood group)
chr7_+_1088106 0.33 ENST00000397088.4
GPER1
G protein-coupled estrogen receptor 1
chr9_-_77648303 0.32 ENST00000341700.7
GNA14
G protein subunit alpha 14
chr10_+_70052806 0.29 ENST00000676609.1
ENST00000679349.1
ENST00000373255.9
ENST00000676608.1
ENST00000455786.1
MACROH2A2
macroH2A.2 histone
chr14_-_21580076 0.27 ENST00000641040.1
ENST00000641185.1
OR10G3
olfactory receptor family 10 subfamily G member 3
chr7_+_66205325 0.27 ENST00000304842.6
ENST00000649664.1
TPST1
tyrosylprotein sulfotransferase 1
chr12_-_121580954 0.25 ENST00000536437.5
ENST00000611216.4
ENST00000538046.6
ENST00000377071.9
KDM2B
lysine demethylase 2B
chr5_+_141213919 0.24 ENST00000341948.6
PCDHB13
protocadherin beta 13
chr3_+_185282941 0.24 ENST00000448876.5
ENST00000446828.5
ENST00000447637.1
ENST00000424227.5
ENST00000454237.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr2_+_74549026 0.21 ENST00000409429.5
DOK1
docking protein 1
chr6_+_89080739 0.21 ENST00000369472.1
ENST00000336032.4
PNRC1
proline rich nuclear receptor coactivator 1
chr11_-_82846128 0.19 ENST00000679809.1
ENST00000680186.1
ENST00000681592.1
PRCP
prolylcarboxypeptidase
chr20_-_45547373 0.18 ENST00000354280.9
EPPIN
epididymal peptidase inhibitor
chr1_-_150765735 0.17 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
CTSS
cathepsin S
chr13_+_101489940 0.16 ENST00000376162.7
ITGBL1
integrin subunit beta like 1
chr3_-_116444983 0.16 ENST00000333617.8
LSAMP
limbic system associated membrane protein
chr20_+_36091409 0.16 ENST00000202028.9
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr2_-_162074394 0.15 ENST00000676810.1
DPP4
dipeptidyl peptidase 4
chr5_-_170267285 0.14 ENST00000521416.5
ENST00000520344.1
LCP2
lymphocyte cytosolic protein 2
chr22_+_37849437 0.13 ENST00000406934.5
ENST00000451427.1
EIF3L
eukaryotic translation initiation factor 3 subunit L
chr3_-_9792691 0.13 ENST00000343450.2
TADA3
transcriptional adaptor 3
chr1_-_8879170 0.12 ENST00000489867.2
ENO1
enolase 1
chr22_+_37849372 0.12 ENST00000624234.3
ENST00000381683.10
ENST00000652021.1
ENST00000414316.5
EIF3L
eukaryotic translation initiation factor 3 subunit L
chr11_+_128693887 0.12 ENST00000281428.12
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr9_+_68356603 0.11 ENST00000396396.6
PGM5
phosphoglucomutase 5
chr16_+_10877181 0.10 ENST00000618207.4
ENST00000618327.4
ENST00000324288.14
ENST00000381835.9
CIITA
class II major histocompatibility complex transactivator
chr17_+_27471999 0.10 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
KSR1
kinase suppressor of ras 1
chr17_-_352784 0.09 ENST00000577079.5
ENST00000331302.12
ENST00000618002.4
ENST00000536489.6
RPH3AL
rabphilin 3A like (without C2 domains)
chr3_-_149576203 0.08 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr4_+_154743993 0.07 ENST00000336356.4
LRAT
lecithin retinol acyltransferase
chr12_+_26121984 0.05 ENST00000538142.5
SSPN
sarcospan
chr2_-_222298974 0.05 ENST00000392069.6
ENST00000392070.7
PAX3
paired box 3
chr19_-_43596123 0.03 ENST00000422989.6
ENST00000598324.1
IRGQ
immunity related GTPase Q
chr9_-_6015607 0.02 ENST00000485372.1
ENST00000259569.6
ENST00000623170.1
RANBP6
RAN binding protein 6
chr22_-_43812190 0.01 ENST00000396231.6
EFCAB6
EF-hand calcium binding domain 6
chr12_+_69348372 0.01 ENST00000261267.7
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr12_+_53454718 0.01 ENST00000552819.5
ENST00000455667.7
PCBP2
poly(rC) binding protein 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 9.9 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
1.2 3.5 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
1.1 3.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.5 6.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.5 6.9 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.4 7.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.4 1.2 GO:0018094 protein polyglycylation(GO:0018094)
0.4 6.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 2.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.4 4.3 GO:0008354 germ cell migration(GO:0008354)
0.3 1.6 GO:0071109 superior temporal gyrus development(GO:0071109)
0.3 3.9 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.3 0.8 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722)
0.3 8.4 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.2 6.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 0.9 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 0.9 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.9 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 3.7 GO:0032060 bleb assembly(GO:0032060)
0.2 2.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 4.6 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 0.5 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 0.7 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.1 1.2 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 15.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.2 GO:0021678 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.1 0.6 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.1 4.0 GO:0008038 neuron recognition(GO:0008038)
0.1 3.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 1.9 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 2.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 3.0 GO:0010107 potassium ion import(GO:0010107)
0.0 3.5 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.2 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.2 GO:0002353 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 1.6 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756) positive regulation of ATP biosynthetic process(GO:2001171)
0.0 1.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 4.1 GO:0007411 axon guidance(GO:0007411)
0.0 0.1 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:1902636 kinociliary basal body(GO:1902636)
0.5 3.8 GO:0036157 outer dynein arm(GO:0036157)
0.5 8.4 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.5 7.5 GO:0097512 cardiac myofibril(GO:0097512)
0.4 9.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.3 3.9 GO:0000124 SAGA complex(GO:0000124)
0.2 0.9 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 0.5 GO:0043159 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 0.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 6.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 18.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 3.5 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 1.6 GO:0033010 paranodal junction(GO:0033010)
0.1 0.8 GO:0044327 dendritic spine head(GO:0044327)
0.1 11.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 1.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.0 GO:0032982 myosin filament(GO:0032982)
0.1 2.3 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 7.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 3.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 5.6 GO:0030027 lamellipodium(GO:0030027)
0.0 3.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 2.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.9 GO:0031902 late endosome membrane(GO:0031902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.7 4.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.4 1.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.3 8.4 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 6.2 GO:0005522 profilin binding(GO:0005522)
0.2 6.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 3.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 3.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.9 GO:0030172 troponin C binding(GO:0030172)
0.1 2.3 GO:0031432 titin binding(GO:0031432)
0.1 0.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 3.5 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 1.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 3.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 3.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 3.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 6.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.8 GO:1990239 steroid hormone binding(GO:1990239)
0.1 6.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 2.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 1.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 2.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 4.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 12.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 4.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0016416 O-palmitoyltransferase activity(GO:0016416)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 9.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 6.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 3.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 3.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 3.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.0 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 6.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 3.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation