Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for NHLH1

Z-value: 4.25

Motif logo

Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
ENSG00000171786.6 NHLH1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg38_v1_chr1_+_160367061_1603670780.194.3e-03Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr16_+_23835946 65.57 ENST00000321728.12
ENST00000643927.1
protein kinase C beta
chr13_-_36131286 32.98 ENST00000255448.8
ENST00000379892.4
doublecortin like kinase 1
chr14_-_23352741 31.16 ENST00000354772.9
solute carrier family 22 member 17
chr8_+_24914942 30.69 ENST00000433454.3
neurofilament medium
chr10_+_103277129 29.86 ENST00000369849.9
internexin neuronal intermediate filament protein alpha
chr6_-_83709019 27.26 ENST00000519779.5
ENST00000369694.6
ENST00000195649.10
synaptosome associated protein 91
chr14_+_99684283 27.26 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr1_+_10210562 24.91 ENST00000377093.9
ENST00000676179.1
kinesin family member 1B
chr6_-_83709141 24.82 ENST00000521743.5
synaptosome associated protein 91
chr6_-_3157536 24.23 ENST00000333628.4
tubulin beta 2A class IIa
chr9_-_109167159 23.63 ENST00000561981.5
ferric chelate reductase 1 like
chr20_+_45408276 22.59 ENST00000372710.5
ENST00000443296.1
dysbindin domain containing 2
chr5_-_74641419 21.98 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ectodermal-neural cortex 1
chr6_-_83709382 21.98 ENST00000520302.5
ENST00000520213.5
ENST00000439399.6
synaptosome associated protein 91
chr7_-_727242 21.88 ENST00000537384.6
ENST00000417852.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr1_-_21622509 21.45 ENST00000374761.6
RAP1 GTPase activating protein
chr8_-_97277890 20.04 ENST00000322128.5
TSPY like 5
chr22_+_31944527 19.56 ENST00000248975.6
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
chr22_+_31944500 19.18 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
chr13_-_36131352 18.96 ENST00000360631.8
doublecortin like kinase 1
chr1_-_85465147 18.87 ENST00000284031.13
dimethylarginine dimethylaminohydrolase 1
chr8_+_24913752 18.68 ENST00000518131.5
ENST00000221166.10
ENST00000437366.2
neurofilament medium
chr19_+_35030626 18.01 ENST00000638536.1
sodium voltage-gated channel beta subunit 1
chr20_+_38805686 17.86 ENST00000299824.6
ENST00000373331.2
protein phosphatase 1 regulatory subunit 16B
chr19_+_4304632 17.85 ENST00000597590.5
fibronectin type III and SPRY domain containing 1
chr16_+_6483379 17.45 ENST00000552089.5
RNA binding fox-1 homolog 1
chr16_+_6483728 17.40 ENST00000675459.1
ENST00000551752.5
RNA binding fox-1 homolog 1
chr16_+_7510102 16.92 ENST00000682918.1
ENST00000683326.1
ENST00000570626.2
RNA binding fox-1 homolog 1
chr1_-_3796478 16.92 ENST00000378251.3
leucine rich repeat containing 47
chr17_-_58529344 16.81 ENST00000317268.7
septin 4
chr19_+_4304588 16.61 ENST00000221856.11
fibronectin type III and SPRY domain containing 1
chr17_-_58529303 16.52 ENST00000580844.5
septin 4
chr17_-_58529277 16.50 ENST00000579371.5
septin 4
chr1_+_51236252 16.39 ENST00000242719.4
ring finger protein 11
chr14_-_23352872 16.29 ENST00000397267.5
solute carrier family 22 member 17
chr4_+_153153023 16.16 ENST00000676458.1
ENST00000675782.1
tripartite motif containing 2
chr16_+_280572 16.14 ENST00000219409.8
Rho GDP dissociation inhibitor gamma
chr16_+_6483813 16.12 ENST00000675653.1
RNA binding fox-1 homolog 1
chr5_+_157266079 15.60 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
cytoplasmic FMR1 interacting protein 2
chr1_+_32886456 15.10 ENST00000373467.4
hippocalcin
chr7_-_727611 15.04 ENST00000403562.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr14_-_103522696 14.99 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
creatine kinase B
chr16_+_280448 14.33 ENST00000447871.5
Rho GDP dissociation inhibitor gamma
chr1_+_50109817 14.13 ENST00000652353.1
ENST00000371821.6
ENST00000652274.1
ELAV like RNA binding protein 4
chr3_+_167735704 13.88 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr19_-_49441508 13.87 ENST00000221485.8
solute carrier family 17 member 7
chr19_+_35030438 13.65 ENST00000415950.5
ENST00000262631.11
sodium voltage-gated channel beta subunit 1
chr17_+_46590669 13.37 ENST00000398238.8
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr1_+_50109620 13.12 ENST00000371819.1
ELAV like RNA binding protein 4
chr19_+_35030711 13.11 ENST00000595652.5
sodium voltage-gated channel beta subunit 1
chrX_+_110944285 13.06 ENST00000425146.5
ENST00000446737.5
p21 (RAC1) activated kinase 3
chr12_-_89708816 12.75 ENST00000428670.8
ATPase plasma membrane Ca2+ transporting 1
chr3_-_133895577 12.51 ENST00000543906.5
RAB6B, member RAS oncogene family
chr4_-_101347327 12.46 ENST00000394853.8
protein phosphatase 3 catalytic subunit alpha
chr3_-_133895867 12.43 ENST00000285208.9
RAB6B, member RAS oncogene family
chr11_-_695215 12.26 ENST00000382409.4
DEAF1 transcription factor
chr11_-_66568524 12.12 ENST00000679160.1
ENST00000678305.1
ENST00000310325.10
ENST00000677896.1
ENST00000677587.1
ENST00000679347.1
ENST00000677005.1
ENST00000678872.1
ENST00000679024.1
ENST00000678471.1
ENST00000524994.6
cathepsin F
chr16_+_1706163 12.01 ENST00000250894.8
ENST00000673691.1
ENST00000356010.9
ENST00000610761.2
mitogen-activated protein kinase 8 interacting protein 3
chr3_-_33659441 12.00 ENST00000650653.1
ENST00000480013.6
cytoplasmic linker associated protein 2
chr14_-_100587404 11.95 ENST00000554140.2
brain enriched guanylate kinase associated
chr15_+_24954912 11.80 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr4_-_101347492 11.78 ENST00000394854.8
protein phosphatase 3 catalytic subunit alpha
chr6_+_30880780 11.69 ENST00000460944.6
ENST00000324771.12
discoidin domain receptor tyrosine kinase 1
chr12_-_6470667 11.49 ENST00000361716.8
ENST00000396308.4
vesicle associated membrane protein 1
chr12_-_27780236 11.45 ENST00000381273.4
MANSC domain containing 4
chr17_-_81166160 11.39 ENST00000326724.9
apoptosis associated tyrosine kinase
chr14_-_23302823 11.38 ENST00000452015.9
protein phosphatase 1 regulatory subunit 3E
chr5_+_72107453 11.38 ENST00000296755.12
ENST00000511641.2
microtubule associated protein 1B
chr4_-_101347471 11.35 ENST00000323055.10
ENST00000512215.5
protein phosphatase 3 catalytic subunit alpha
chr4_+_153153105 11.05 ENST00000437508.7
tripartite motif containing 2
chr6_+_29656993 10.94 ENST00000376888.6
myelin oligodendrocyte glycoprotein
chr1_-_177164673 10.93 ENST00000424564.2
ENST00000361833.7
astrotactin 1
chr11_-_66347560 10.80 ENST00000311181.5
beta-1,4-glucuronyltransferase 1
chr2_-_86337617 10.68 ENST00000538924.7
ENST00000535845.6
receptor accessory protein 1
chr1_+_50109788 10.64 ENST00000651258.1
ELAV like RNA binding protein 4
chr16_-_29899043 10.63 ENST00000346932.9
ENST00000350527.7
ENST00000568380.1
seizure related 6 homolog like 2
chr11_+_65890627 10.62 ENST00000312579.4
coiled-coil domain containing 85B
chr1_+_87331668 10.52 ENST00000370542.1
LIM domain only 4
chr6_+_29657085 10.38 ENST00000376917.8
ENST00000376894.8
myelin oligodendrocyte glycoprotein
chr17_-_80476597 10.18 ENST00000306773.5
neuronal pentraxin 1
chr17_+_68259164 10.12 ENST00000448504.6
arylsulfatase G
chr1_-_182391783 10.11 ENST00000331872.11
ENST00000339526.8
glutamate-ammonia ligase
chr14_-_26598025 10.06 ENST00000539517.7
NOVA alternative splicing regulator 1
chr2_-_86337654 9.96 ENST00000165698.9
receptor accessory protein 1
chr6_+_29657120 9.88 ENST00000396704.7
ENST00000416766.6
ENST00000483013.5
ENST00000490427.5
ENST00000376891.8
ENST00000376898.7
ENST00000396701.6
ENST00000494692.5
ENST00000431798.6
myelin oligodendrocyte glycoprotein
chr15_+_43510945 9.85 ENST00000382031.5
microtubule associated protein 1A
chr4_-_185775890 9.81 ENST00000437304.6
sorbin and SH3 domain containing 2
chr9_-_89178810 9.73 ENST00000375835.9
SHC adaptor protein 3
chr1_-_182391363 9.50 ENST00000417584.6
glutamate-ammonia ligase
chr3_+_35639589 9.33 ENST00000428373.5
cAMP regulated phosphoprotein 21
chr19_+_46601296 9.29 ENST00000598871.5
ENST00000291295.14
ENST00000594523.5
calmodulin 3
chr10_+_132537778 9.21 ENST00000368594.8
inositol polyphosphate-5-phosphatase A
chr11_+_17734732 9.09 ENST00000379472.4
ENST00000675775.1
ENST00000265969.8
ENST00000640318.2
ENST00000639325.2
potassium voltage-gated channel subfamily C member 1
chr12_-_6470643 8.95 ENST00000535180.5
ENST00000400911.7
vesicle associated membrane protein 1
chr16_+_56191476 8.91 ENST00000262493.12
G protein subunit alpha o1
chr16_-_29899245 8.85 ENST00000537485.5
seizure related 6 homolog like 2
chr9_-_76692181 8.81 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chr14_-_64972143 8.73 ENST00000267512.9
RAB15, member RAS oncogene family
chr1_+_228487356 8.72 ENST00000305943.9
ring finger protein 187
chr12_+_120650492 8.68 ENST00000351200.6
calcium binding protein 1
chr10_-_125823221 8.67 ENST00000420761.5
ENST00000368797.10
uroporphyrinogen III synthase
chr8_+_85463997 8.56 ENST00000285379.10
carbonic anhydrase 2
chr19_-_3061403 8.56 ENST00000586839.1
TLE family member 5, transcriptional modulator
chr19_+_10106688 8.39 ENST00000430370.1
peter pan homolog
chr7_+_111091119 8.30 ENST00000308478.10
leucine rich repeat neuronal 3
chr13_+_34942263 8.24 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr11_-_35419542 8.17 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
solute carrier family 1 member 2
chr11_-_66958366 8.17 ENST00000651036.1
ENST00000652125.1
ENST00000531614.6
ENST00000524491.6
ENST00000529047.6
ENST00000393960.7
ENST00000393958.7
ENST00000528403.6
ENST00000651854.1
pyruvate carboxylase
chr7_+_45574358 8.15 ENST00000297323.12
adenylate cyclase 1
chr18_+_11689210 8.04 ENST00000334049.11
G protein subunit alpha L
chr6_-_166627244 7.94 ENST00000265678.9
ribosomal protein S6 kinase A2
chr10_-_125823089 7.86 ENST00000368774.1
ENST00000368778.7
ENST00000649536.1
uroporphyrinogen III synthase
chr15_+_40252888 7.76 ENST00000559139.5
ENST00000560669.5
ENST00000542403.3
p21 (RAC1) activated kinase 6
chr8_+_41490553 7.67 ENST00000405786.2
ENST00000357743.9
golgin A7
chr7_+_111091006 7.63 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr12_+_7155867 7.53 ENST00000535313.2
ENST00000331148.5
calsyntenin 3
chr6_-_154510675 7.53 ENST00000607772.6
CNKSR family member 3
chr19_-_49072699 7.50 ENST00000221444.2
potassium voltage-gated channel subfamily A member 7
chr16_+_22814154 7.48 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr4_-_185775271 7.47 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr3_-_73624840 7.46 ENST00000308537.4
ENST00000263666.9
PDZ domain containing ring finger 3
chr2_-_73284431 7.45 ENST00000521871.5
ENST00000520530.3
F-box protein 41
chr16_-_74774812 7.40 ENST00000219368.8
fatty acid 2-hydroxylase
chr17_-_28951285 7.21 ENST00000577226.5
PHD finger protein 12
chr5_+_140114085 7.20 ENST00000331327.5
purine rich element binding protein A
chrX_-_69165509 7.09 ENST00000361478.1
praja ring finger ubiquitin ligase 1
chr14_-_64972233 7.07 ENST00000533601.7
RAB15, member RAS oncogene family
chrX_-_69165430 7.03 ENST00000374584.3
ENST00000590146.1
ENST00000374571.5
praja ring finger ubiquitin ligase 1
chr7_-_712940 7.00 ENST00000544935.5
ENST00000430040.5
ENST00000456696.2
ENST00000406797.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr4_+_70704713 6.85 ENST00000417478.6
RUN and FYVE domain containing 3
chr3_-_195909711 6.66 ENST00000333602.14
tyrosine kinase non receptor 2
chr8_+_135457442 6.56 ENST00000355849.10
KH RNA binding domain containing, signal transduction associated 3
chr5_-_218136 6.39 ENST00000296824.4
coiled-coil domain containing 127
chr17_-_58517835 6.39 ENST00000579921.1
ENST00000579925.5
ENST00000323456.9
myotubularin related protein 4
chr4_-_36244438 6.30 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_23821275 6.30 ENST00000380110.8
ELAV like RNA binding protein 2
chr11_+_12110569 6.25 ENST00000683283.1
ENST00000256194.8
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr16_-_29926155 6.11 ENST00000567795.3
ENST00000568000.6
ENST00000561540.2
potassium channel tetramerization domain containing 13
chr1_+_174877430 6.02 ENST00000392064.6
RAB GTPase activating protein 1 like
chr11_-_35420050 6.01 ENST00000395753.6
ENST00000395750.6
ENST00000645634.1
solute carrier family 1 member 2
chr19_+_46601237 6.00 ENST00000597743.5
calmodulin 3
chr2_+_65056382 5.81 ENST00000377990.7
ENST00000537589.1
ENST00000260569.4
centrosomal protein 68
chr11_+_61766073 5.80 ENST00000675319.1
myelin regulatory factor
chr2_-_11670186 5.78 ENST00000306928.6
neurotensin receptor 2
chr5_-_134411847 5.51 ENST00000458198.3
ENST00000395009.3
CDKN2A interacting protein N-terminal like
chr2_-_229271221 5.47 ENST00000392054.7
ENST00000409462.1
ENST00000392055.8
phosphotyrosine interaction domain containing 1
chr16_+_19211157 5.44 ENST00000568433.1
synaptotagmin 17
chr1_-_84690406 5.42 ENST00000605755.5
ENST00000342203.8
ENST00000437941.6
SSX family member 2 interacting protein
chr1_-_237004440 5.41 ENST00000464121.3
metallothionein 1H like 1
chr7_+_73433761 5.37 ENST00000344575.5
frizzled class receptor 9
chr11_-_61430008 5.31 ENST00000394888.8
cleavage and polyadenylation specific factor 7
chr1_-_83999097 5.29 ENST00000260505.13
ENST00000610996.1
tubulin tyrosine ligase like 7
chr2_+_10911924 5.20 ENST00000295082.3
potassium voltage-gated channel modifier subfamily F member 1
chr1_-_153946652 5.09 ENST00000361217.9
DENN domain containing 4B
chr7_+_100015572 5.03 ENST00000535170.5
zinc finger with KRAB and SCAN domains 1
chr9_+_122941003 5.00 ENST00000373647.9
ENST00000402311.5
RAB GTPase activating protein 1
chr4_+_61201223 4.96 ENST00000512091.6
adhesion G protein-coupled receptor L3
chrX_-_43973382 4.96 ENST00000642620.1
ENST00000647044.1
norrin cystine knot growth factor NDP
chr15_+_79311137 4.95 ENST00000424155.6
ENST00000536821.5
transmembrane p24 trafficking protein 3
chrX_-_6227180 4.94 ENST00000381093.6
neuroligin 4 X-linked
chr11_-_61429934 4.94 ENST00000541963.5
ENST00000477890.6
ENST00000439958.8
cleavage and polyadenylation specific factor 7
chr19_-_14206168 4.90 ENST00000361434.7
ENST00000340736.10
adhesion G protein-coupled receptor L1
chr19_-_46661132 4.83 ENST00000410105.2
ENST00000391916.7
dishevelled binding antagonist of beta catenin 3
chr11_+_71527267 4.77 ENST00000398536.6
keratin associated protein 5-7
chr1_+_89524819 4.74 ENST00000439853.6
ENST00000330947.7
ENST00000449440.5
ENST00000640258.1
leucine rich repeat containing 8 VRAC subunit B
chr9_+_128818491 4.73 ENST00000372642.5
endonuclease G
chr1_+_89524871 4.72 ENST00000639264.1
leucine rich repeat containing 8 VRAC subunit B
chr19_-_58558871 4.70 ENST00000595957.5
ubiquitin conjugating enzyme E2 M
chr2_+_235669602 4.69 ENST00000409538.5
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr1_-_56579555 4.61 ENST00000371250.4
phospholipid phosphatase 3
chr4_+_122152308 4.59 ENST00000679879.1
ENST00000264501.8
KIAA1109
chr17_-_75405647 4.46 ENST00000316804.10
ENST00000316615.9
growth factor receptor bound protein 2
chr15_-_52179881 4.36 ENST00000396335.8
ENST00000560116.1
ENST00000358784.11
G protein subunit beta 5
chr1_-_201023694 4.36 ENST00000332129.6
ENST00000422435.2
ENST00000461742.7
kinesin family member 21B
chr14_+_104865256 4.35 ENST00000414716.8
ENST00000556508.5
ENST00000453495.2
centrosomal protein 170B
chr19_-_5978133 4.32 ENST00000340578.10
ENST00000591736.5
ENST00000587479.2
RAN binding protein 3
chr12_-_123268077 4.30 ENST00000542174.5
cyclin dependent kinase 2 associated protein 1
chr19_-_5978078 4.28 ENST00000592621.5
ENST00000034275.12
ENST00000591092.5
ENST00000591333.5
ENST00000590623.5
ENST00000439268.6
RAN binding protein 3
chr2_+_8682046 4.27 ENST00000331129.3
ENST00000396290.2
inhibitor of DNA binding 2
chr17_+_28042660 4.24 ENST00000407008.8
nemo like kinase
chr17_-_76726753 4.20 ENST00000617192.4
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr18_-_55586092 4.18 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr12_+_131949893 4.17 ENST00000389561.7
ENST00000332482.8
ENST00000333577.8
E1A binding protein p400
chr2_-_73112885 4.15 ENST00000486777.7
RAB11 family interacting protein 5
chr17_-_75405486 4.08 ENST00000392562.5
growth factor receptor bound protein 2
chr19_-_58558561 4.04 ENST00000253023.8
ubiquitin conjugating enzyme E2 M
chr17_-_33293247 4.04 ENST00000225823.7
acid sensing ion channel subunit 2
chr2_+_15940537 4.03 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr14_-_24442765 4.02 ENST00000555365.5
ENST00000399395.8
ENST00000553930.5
short chain dehydrogenase/reductase family 39U member 1
chr16_+_83899079 4.01 ENST00000262430.6
malonyl-CoA decarboxylase
chr7_+_100015588 3.98 ENST00000324306.11
ENST00000426572.5
zinc finger with KRAB and SCAN domains 1
chr4_+_41360759 3.95 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIM and calponin homology domains 1
chr13_-_95644690 3.94 ENST00000361396.6
ENST00000376829.7
DAZ interacting zinc finger protein 1
chr19_+_5904856 3.93 ENST00000339485.4
vimentin type intermediate filament associated coiled-coil protein
chr19_-_5567984 3.91 ENST00000448587.5
TINCR ubiquitin domain containing
chr3_+_43286512 3.90 ENST00000454177.5
ENST00000429705.6
ENST00000296088.12
ENST00000437827.1
SNF related kinase
chr19_-_45493208 3.89 ENST00000430715.6
reticulon 2
chr4_+_40056790 3.86 ENST00000261435.11
ENST00000515550.1
NEDD4 binding protein 2
chr4_+_176065827 3.86 ENST00000508596.6
WD repeat domain 17
chrX_+_119236245 3.86 ENST00000535419.2
progesterone receptor membrane component 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
13.1 65.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
12.3 49.4 GO:0033693 neurofilament bundle assembly(GO:0033693)
9.5 47.5 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
8.9 35.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
7.5 44.8 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
6.0 17.9 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
4.9 19.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
4.6 13.9 GO:0042137 sequestering of neurotransmitter(GO:0042137)
4.1 16.5 GO:0071418 cellular response to amine stimulus(GO:0071418)
3.7 29.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
3.4 16.9 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.9 47.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
2.9 8.6 GO:0042938 dipeptide transport(GO:0042938)
2.7 21.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
2.5 15.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
2.5 27.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
2.4 80.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
2.4 4.7 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
2.3 9.1 GO:0021759 globus pallidus development(GO:0021759)
2.2 15.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
2.2 10.8 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
2.2 15.1 GO:1902075 cellular response to salt(GO:1902075)
2.1 12.7 GO:1990034 calcium ion export from cell(GO:1990034)
2.1 6.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
2.0 8.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.0 22.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.9 7.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.8 5.5 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
1.8 5.4 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
1.5 7.5 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
1.5 38.7 GO:0006706 steroid catabolic process(GO:0006706)
1.4 4.3 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
1.4 4.2 GO:0070078 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
1.3 11.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.3 3.8 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
1.2 4.7 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
1.2 51.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
1.1 1.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
1.1 12.0 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
1.1 20.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
1.1 8.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.0 10.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
1.0 18.9 GO:0043116 negative regulation of vascular permeability(GO:0043116)
1.0 5.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.0 20.4 GO:0035493 SNARE complex assembly(GO:0035493)
1.0 6.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.9 30.3 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.9 2.8 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
0.9 7.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.9 2.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.9 3.5 GO:0030035 microspike assembly(GO:0030035)
0.8 5.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.8 12.4 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.8 4.0 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.8 4.0 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.8 3.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.8 57.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.8 2.3 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.8 10.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.7 2.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.7 2.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.7 7.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.6 6.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.6 8.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6 4.9 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.6 5.5 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.6 1.8 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.6 3.6 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.6 1.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.6 2.8 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.6 7.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 2.7 GO:0071494 cellular response to UV-C(GO:0071494)
0.5 12.3 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.5 8.4 GO:1900364 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) negative regulation of mRNA polyadenylation(GO:1900364)
0.5 2.6 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.5 2.0 GO:1990637 response to prolactin(GO:1990637)
0.5 13.1 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.5 2.5 GO:0030242 pexophagy(GO:0030242)
0.5 4.9 GO:0003360 brainstem development(GO:0003360)
0.5 3.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.5 8.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.5 4.6 GO:0008354 germ cell migration(GO:0008354)
0.5 1.8 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.4 20.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.4 2.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4 3.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.4 2.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.4 6.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.4 4.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.4 5.2 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.4 3.1 GO:0042426 choline catabolic process(GO:0042426)
0.4 3.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.4 23.6 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.4 1.9 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.4 4.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.4 15.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.4 25.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.4 12.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.4 10.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 1.4 GO:0071233 cellular response to leucine(GO:0071233)
0.3 3.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.3 13.1 GO:0045026 plasma membrane fusion(GO:0045026)
0.3 7.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.3 0.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.3 2.8 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.3 20.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 8.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.3 0.9 GO:0014736 regulation of muscle atrophy(GO:0014735) negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876)
0.3 2.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3 2.2 GO:0035411 catenin import into nucleus(GO:0035411)
0.3 2.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 0.5 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.3 1.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.3 4.4 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.3 2.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 1.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 3.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 2.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 2.2 GO:0045176 apical protein localization(GO:0045176)
0.2 0.7 GO:0061760 antifungal innate immune response(GO:0061760)
0.2 1.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.2 13.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 1.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 2.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 3.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 6.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 3.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 1.5 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 2.9 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 5.8 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 6.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 9.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.2 4.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 3.6 GO:0006828 manganese ion transport(GO:0006828)
0.2 3.8 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 0.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 2.7 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.2 2.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.2 1.5 GO:0021516 dorsal spinal cord development(GO:0021516)
0.2 1.5 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 9.2 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.2 0.7 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.5 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.2 4.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.2 7.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.2 5.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 5.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 10.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.2 2.6 GO:0045116 protein neddylation(GO:0045116)
0.2 1.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 2.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 2.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 2.4 GO:0048820 hair follicle maturation(GO:0048820)
0.1 0.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.0 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.1 29.8 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 1.0 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 1.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.9 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.1 2.7 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 3.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.6 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 20.2 GO:0046718 viral entry into host cell(GO:0046718)
0.1 0.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 4.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 3.8 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.1 1.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 8.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.5 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 7.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 2.5 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 14.0 GO:0044070 regulation of anion transport(GO:0044070)
0.1 0.4 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 5.4 GO:0006906 vesicle fusion(GO:0006906)
0.1 2.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 7.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.5 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 7.4 GO:0005977 glycogen metabolic process(GO:0005977)
0.1 0.3 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) positive regulation of gastric acid secretion(GO:0060454) response to capsazepine(GO:1901594)
0.1 3.9 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.1 3.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.7 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 4.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.1 0.7 GO:0007512 adult heart development(GO:0007512)
0.1 12.9 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.1 2.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 6.5 GO:0021987 cerebral cortex development(GO:0021987)
0.1 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.5 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 3.9 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.1 2.6 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 1.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 2.3 GO:0006040 amino sugar metabolic process(GO:0006040)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 2.1 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 5.1 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 3.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 8.4 GO:0006397 mRNA processing(GO:0006397)
0.0 2.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0060214 stem cell fate commitment(GO:0048865) endocardium formation(GO:0060214)
0.0 0.4 GO:0042073 intraciliary transport(GO:0042073)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.9 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
5.0 79.2 GO:0005883 neurofilament(GO:0005883)
3.2 35.6 GO:0005955 calcineurin complex(GO:0005955)
2.2 47.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
2.2 15.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
1.8 44.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.7 13.9 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
1.7 8.4 GO:0032044 DSIF complex(GO:0032044)
1.7 15.1 GO:0044327 dendritic spine head(GO:0044327)
1.3 7.7 GO:0002178 palmitoyltransferase complex(GO:0002178)
1.2 12.0 GO:0045180 basal cortex(GO:0045180)
0.8 3.4 GO:0034457 Mpp10 complex(GO:0034457)
0.8 20.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.8 11.8 GO:0005687 U4 snRNP(GO:0005687)
0.7 20.1 GO:0097386 glial cell projection(GO:0097386)
0.7 21.8 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.7 3.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.6 3.9 GO:0098827 terminal cisterna(GO:0014802) endoplasmic reticulum subcompartment(GO:0098827)
0.6 48.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.6 63.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.5 12.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.5 8.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 3.8 GO:0072487 MSL complex(GO:0072487)
0.4 31.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4 8.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 26.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4 2.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.4 29.8 GO:0014704 intercalated disc(GO:0014704)
0.4 21.0 GO:0005871 kinesin complex(GO:0005871)
0.3 10.4 GO:0030673 axolemma(GO:0030673)
0.3 2.3 GO:0097165 nuclear stress granule(GO:0097165)
0.3 22.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 3.1 GO:0070852 cell body fiber(GO:0070852)
0.3 2.7 GO:0000125 PCAF complex(GO:0000125)
0.3 4.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 68.4 GO:0005802 trans-Golgi network(GO:0005802)
0.3 40.0 GO:0043204 perikaryon(GO:0043204)
0.3 3.1 GO:0030870 Mre11 complex(GO:0030870)
0.3 90.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 2.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 2.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 1.4 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 6.5 GO:0031527 filopodium membrane(GO:0031527)
0.2 4.4 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.5 GO:0016272 prefoldin complex(GO:0016272)
0.2 1.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 2.0 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 7.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.8 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.2 7.5 GO:0031594 neuromuscular junction(GO:0031594)
0.2 2.0 GO:0090543 Flemming body(GO:0090543)
0.2 3.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 18.5 GO:0055037 recycling endosome(GO:0055037)
0.1 4.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 7.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 14.9 GO:0005875 microtubule associated complex(GO:0005875)
0.1 13.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 38.9 GO:0031301 integral component of organelle membrane(GO:0031301)
0.1 0.5 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0002081 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.1 21.4 GO:0001650 fibrillar center(GO:0001650)
0.1 2.5 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 2.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 15.0 GO:0030018 Z disc(GO:0030018)
0.1 0.5 GO:0035841 growing cell tip(GO:0035838) new growing cell tip(GO:0035841) cell tip(GO:0051286)
0.1 1.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 1.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 6.5 GO:0005902 microvillus(GO:0005902)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.1 12.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 3.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 1.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 2.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 24.3 GO:0043025 neuronal cell body(GO:0043025)
0.1 6.9 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.1 GO:0042629 mast cell granule(GO:0042629)
0.1 19.8 GO:0005874 microtubule(GO:0005874)
0.1 0.3 GO:0070187 telosome(GO:0070187)
0.1 5.3 GO:0000922 spindle pole(GO:0000922)
0.1 3.8 GO:0042641 actomyosin(GO:0042641)
0.1 2.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 46.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 2.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 17.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 4.5 GO:0030133 transport vesicle(GO:0030133)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 3.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 9.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 2.0 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0043679 axon terminus(GO:0043679)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
16.4 65.6 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
9.0 44.8 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
6.9 20.6 GO:0031849 olfactory receptor binding(GO:0031849)
4.9 19.6 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
4.1 16.5 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
4.0 35.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
3.8 30.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
3.4 16.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
2.8 13.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
2.7 8.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
2.7 18.9 GO:0016403 dimethylargininase activity(GO:0016403)
2.7 70.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
2.4 47.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
2.2 15.5 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
2.2 10.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.9 11.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.9 15.0 GO:0004111 creatine kinase activity(GO:0004111)
1.9 7.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.8 5.5 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
1.8 7.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.6 14.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.4 4.3 GO:0032093 SAM domain binding(GO:0032093)
1.4 4.2 GO:0033749 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
1.3 34.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.3 3.8 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
1.2 3.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.0 4.0 GO:0044736 acid-sensing ion channel activity(GO:0044736)
1.0 3.9 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.0 4.8 GO:0070097 delta-catenin binding(GO:0070097)
0.9 9.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) PH domain binding(GO:0042731)
0.9 12.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.9 3.5 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.9 12.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.9 8.6 GO:0004064 arylesterase activity(GO:0004064)
0.8 10.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.8 3.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.8 28.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.8 33.1 GO:0017091 AU-rich element binding(GO:0017091)
0.8 3.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.8 4.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.8 3.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.8 12.0 GO:0002162 dystroglycan binding(GO:0002162)
0.7 8.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.7 8.2 GO:0004075 biotin carboxylase activity(GO:0004075)
0.7 17.6 GO:0031489 myosin V binding(GO:0031489)
0.7 8.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.7 36.7 GO:0019894 kinesin binding(GO:0019894)
0.6 118.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.6 2.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.5 13.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 4.2 GO:1990405 protein antigen binding(GO:1990405)
0.5 1.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.5 20.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.5 3.8 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.5 2.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 12.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 6.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.4 7.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4 1.4 GO:0001855 complement component C4b binding(GO:0001855)
0.3 1.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.3 1.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 3.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 4.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 6.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 2.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.3 3.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 2.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 5.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 2.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.3 20.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 2.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 7.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.8 GO:0019863 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.2 3.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 8.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 1.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 6.2 GO:0071949 FAD binding(GO:0071949)
0.2 8.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 2.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2 25.3 GO:0001618 virus receptor activity(GO:0001618)
0.2 4.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 2.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 8.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 0.9 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2 7.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 0.9 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 0.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 3.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 6.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 36.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.2 1.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 5.0 GO:0005109 frizzled binding(GO:0005109)
0.2 6.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 11.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 8.6 GO:0070412 R-SMAD binding(GO:0070412)
0.2 3.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 37.4 GO:0003924 GTPase activity(GO:0003924)
0.1 13.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.5 GO:0019215 intermediate filament binding(GO:0019215)
0.1 5.4 GO:0019905 syntaxin binding(GO:0019905)
0.1 2.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 55.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 12.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 2.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.3 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.9 GO:0089720 caspase binding(GO:0089720)
0.1 3.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 3.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 2.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 21.8 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.1 2.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 11.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 24.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 2.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 2.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 3.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 5.1 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 0.9 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 6.2 GO:0020037 heme binding(GO:0020037)
0.1 4.7 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.9 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.1 GO:0035497 cAMP response element binding(GO:0035497)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 65.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.9 35.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.7 27.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.7 35.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.7 16.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.7 19.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5 32.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 17.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.4 33.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.4 20.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.4 14.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 8.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 8.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 13.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 6.3 PID ARF6 PATHWAY Arf6 signaling events
0.2 4.4 PID CONE PATHWAY Visual signal transduction: Cones
0.2 6.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 6.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.9 PID SHP2 PATHWAY SHP2 signaling
0.1 2.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 10.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 7.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 1.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 20.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 4.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 78.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
2.4 28.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.7 55.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
1.6 8.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
1.3 51.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.1 48.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.0 21.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.8 23.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.8 10.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.8 20.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 19.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.6 13.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.6 16.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.5 21.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.5 8.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.5 13.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 21.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.4 6.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.4 2.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.4 3.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.4 5.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.3 7.0 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.3 7.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 3.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 7.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.2 39.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 7.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.2 3.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 2.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 9.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 3.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.9 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 3.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors