avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
NKX2-1 | hg38_v1_chr14_-_36521149_36521191, hg38_v1_chr14_-_36520222_36520237, hg38_v1_chr14_-_36519679_36519693 | 0.13 | 6.2e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 12.2 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
1.2 | 12.0 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.6 | 11.0 | GO:0006089 | lactate metabolic process(GO:0006089) |
0.0 | 6.4 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
1.2 | 6.2 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
1.2 | 6.2 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
1.3 | 5.2 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
0.0 | 4.6 | GO:0042100 | B cell proliferation(GO:0042100) |
1.1 | 4.4 | GO:0035750 | protein localization to myelin sheath abaxonal region(GO:0035750) |
0.3 | 4.3 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 15.3 | GO:0045121 | membrane raft(GO:0045121) |
2.0 | 12.2 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
0.8 | 12.0 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.5 | 6.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.3 | 6.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 5.6 | GO:0015030 | Cajal body(GO:0015030) |
0.0 | 5.4 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.5 | 5.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.4 | 4.6 | GO:0097486 | multivesicular body lumen(GO:0097486) |
0.3 | 4.4 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 16.5 | GO:0051087 | chaperone binding(GO:0051087) |
3.0 | 12.0 | GO:0047676 | arachidonate-CoA ligase activity(GO:0047676) |
1.6 | 11.0 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
0.4 | 8.1 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.2 | 5.8 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.2 | 4.6 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
0.1 | 4.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.2 | 3.9 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 3.4 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
1.1 | 3.3 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.6 | PID PLK1 PATHWAY | PLK1 signaling events |
0.1 | 5.0 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 5.0 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
0.1 | 4.3 | PID AURORA A PATHWAY | Aurora A signaling |
0.0 | 4.3 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 4.0 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.1 | 3.2 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.1 | 2.1 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
0.1 | 2.0 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
0.0 | 1.8 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 12.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
0.4 | 12.0 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.3 | 11.0 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
0.3 | 7.2 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
0.3 | 6.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.1 | 4.4 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
0.1 | 4.4 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
0.0 | 4.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.2 | 4.0 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.1 | 3.9 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |