avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
NKX2-8 Links Ensembl NCBI GeneCards UniProt	ENSG00000136327.7	NKX2-8

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NKX2-8	hg38_v1_chr14_-_36582593_36582626	0.12	8.6e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr16_+_176659 Show fit	17.98	ENST00000320868.9 ENST00000397797.1	HBA1 Links Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit alpha 1
chr11_+_72080595 Show fit	17.25	ENST00000647530.1 ENST00000539271.6 ENST00000642510.1	LRTOMT Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing
chr16_+_172869 Show fit	16.02	ENST00000251595.11 ENST00000397806.1 ENST00000484216.1	HBA2 Links Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit alpha 2
chr11_+_72080803 Show fit	13.25	ENST00000423494.6 ENST00000539587.6 ENST00000536917.2 ENST00000538478.5 ENST00000324866.11 ENST00000643715.1 ENST00000439209.5	LRTOMT Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000284922.2 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing leucine rich transmembrane and O-methyltransferase domain containing
chr14_-_105626066 Show fit	12.47	ENST00000641978.1 ENST00000390543.3	IGHG4 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant gamma 4 (G4m marker)
chr14_-_105856183 Show fit	11.27	ENST00000637539.2 ENST00000390559.6	IGHM Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant mu
chr14_-_106507476 Show fit	10.48	ENST00000390621.3	IGHV1-45 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-45
chr17_-_69150062 Show fit	10.34	ENST00000522787.5 ENST00000521538.5	ABCA10 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 10
chr12_+_25052512 Show fit	9.64	ENST00000557489.5 ENST00000354454.7 ENST00000536173.5	IRAG2 Links Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr12_+_25052634 Show fit	9.37	ENST00000548766.5	IRAG2 Links Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr16_-_33845229 Show fit	8.99	ENST00000569103.2	IGHV3OR16-17 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr12_+_50112167 Show fit	8.65	ENST00000548468.2 ENST00000552815.1 ENST00000550654.1 ENST00000550487.6 ENST00000548985.1	ENSG00000272368.2 Links Ensembl NCBI GeneCards UniProt Show fit COX14 Links Ensembl NCBI GeneCards UniProt Show fit	novel transcript, antisense to CERS5 cytochrome c oxidase assembly factor COX14
chr14_-_106538331 Show fit	7.92	ENST00000390624.3	IGHV3-48 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-48
chr2_-_89010515 Show fit	7.81	ENST00000493819.1	IGKV1-9 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr1_+_152985231 Show fit	7.66	ENST00000368762.1	SPRR1A Links Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 1A
chr14_-_106675544 Show fit	7.20	ENST00000390632.2	IGHV3-66 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-66
chr14_-_106875069 Show fit	6.98	ENST00000390639.2	IGHV7-81 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 7-81 (non-functional)
chr2_-_135531172 Show fit	6.74	ENST00000264159.11	ZRANB3 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger RANBP2-type containing 3
chr14_-_106593319 Show fit	6.65	ENST00000390627.3	IGHV3-53 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-53
chr3_-_115071333 Show fit	6.33	ENST00000462705.5	ZBTB20 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr14_-_106235582 Show fit	6.30	ENST00000390607.2	IGHV3-21 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-21
chr14_-_106269133 Show fit	6.13	ENST00000390609.3	IGHV3-23 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-23
chr12_+_25052732 Show fit	6.05	ENST00000547044.5	IRAG2 Links Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr14_-_106088573 Show fit	6.00	ENST00000632099.1	IGHV3-64D Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64D
chr2_-_151261839 Show fit	5.66	ENST00000331426.6	RBM43 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 43
chr5_+_81233314 Show fit	5.32	ENST00000511719.5 ENST00000437669.5 ENST00000254035.9 ENST00000424301.6 ENST00000505060.1	CKMT2 Links Ensembl NCBI GeneCards UniProt Show fit	creatine kinase, mitochondrial 2
chr11_-_114595750 Show fit	5.11	ENST00000424261.6	NXPE4 Links Ensembl NCBI GeneCards UniProt Show fit	neurexophilin and PC-esterase domain family member 4
chr8_-_65842051 Show fit	4.89	ENST00000401827.8	PDE7A Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 7A
chr3_-_114624921 Show fit	4.69	ENST00000393785.6	ZBTB20 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr14_-_106470788 Show fit	4.68	ENST00000434710.1	IGHV3-43 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-43
chr1_+_172420681 Show fit	4.63	ENST00000367727.9	C1orf105 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 105
chr7_+_100219236 Show fit	4.58	ENST00000317271.2	PVRIG Links Ensembl NCBI GeneCards UniProt Show fit	PVR related immunoglobulin domain containing
chr14_-_106811131 Show fit	4.56	ENST00000424969.2	IGHV3-74 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-74
chr11_-_72642407 Show fit	4.44	ENST00000376450.7	PDE2A Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr1_+_54998927 Show fit	4.40	ENST00000651561.1	BSND Links Ensembl NCBI GeneCards UniProt Show fit	barttin CLCNK type accessory subunit beta
chr11_-_72642450 Show fit	4.33	ENST00000444035.6 ENST00000544570.5	PDE2A Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr11_-_5249836 Show fit	4.30	ENST00000632727.1 ENST00000330597.5	HBG1 Links Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit gamma 1
chr3_-_122416035 Show fit	4.30	ENST00000330689.6	WDR5B Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 5B
chr15_-_34754989 Show fit	4.27	ENST00000290374.5	GJD2 Links Ensembl NCBI GeneCards UniProt Show fit	gap junction protein delta 2
chr3_-_114624193 Show fit	4.21	ENST00000481632.5	ZBTB20 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr14_+_35046238 Show fit	4.18	ENST00000280987.9	FAM177A1 Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 177 member A1
chr22_+_29438583 Show fit	4.06	ENST00000354373.2	RFPL1 Links Ensembl NCBI GeneCards UniProt Show fit	ret finger protein like 1
chr22_+_19131271 Show fit	4.01	ENST00000399635.4	TSSK2 Links Ensembl NCBI GeneCards UniProt Show fit	testis specific serine kinase 2
chr3_-_39051935 Show fit	3.76	ENST00000668754.1 ENST00000302328.9	SCN11A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 11
chr5_+_34929572 Show fit	3.73	ENST00000382021.2	DNAJC21 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C21
chr20_+_43514492 Show fit	3.73	ENST00000373135.8 ENST00000373134.5	L3MBTL1 Links Ensembl NCBI GeneCards UniProt Show fit	L3MBTL histone methyl-lysine binding protein 1
chr2_+_100974849 Show fit	3.64	ENST00000450763.1	NPAS2 Links Ensembl NCBI GeneCards UniProt Show fit	neuronal PAS domain protein 2
chr10_-_73641450 Show fit	3.63	ENST00000359322.5	MYOZ1 Links Ensembl NCBI GeneCards UniProt Show fit	myozenin 1
chr1_+_32205657 Show fit	3.61	ENST00000291358.11 ENST00000537469.2	IQCC Links Ensembl NCBI GeneCards UniProt Show fit	IQ motif containing C
chr5_+_34929524 Show fit	3.58	ENST00000648817.1	DNAJC21 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C21
chr2_-_63588390 Show fit	3.57	ENST00000272321.12 ENST00000409562.7	WDPCP Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat containing planar cell polarity effector
chr15_+_45129933 Show fit	3.54	ENST00000321429.8 ENST00000389037.7 ENST00000558322.5	DUOX1 Links Ensembl NCBI GeneCards UniProt Show fit	dual oxidase 1
chr18_-_46917432 Show fit	3.53	ENST00000324794.11 ENST00000545673.5 ENST00000585916.6	PIAS2 Links Ensembl NCBI GeneCards UniProt Show fit	protein inhibitor of activated STAT 2
chr16_+_29663219 Show fit	3.49	ENST00000436527.5 ENST00000360121.4 ENST00000652691.1 ENST00000449759.2	SPN Links Ensembl NCBI GeneCards UniProt Show fit QPRT Links Ensembl NCBI GeneCards UniProt Show fit	sialophorin quinolinate phosphoribosyltransferase
chr17_-_7208325 Show fit	3.41	ENST00000650120.1 ENST00000648760.1	DLG4 Links Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 4
chr14_-_106211453 Show fit	3.41	ENST00000390606.3	IGHV3-20 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-20
chr10_+_17752185 Show fit	3.40	ENST00000377495.2	TMEM236 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 236
chr3_+_111998739 Show fit	3.36	ENST00000393917.6 ENST00000273368.8	TAGLN3 Links Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chr17_-_44968263 Show fit	3.26	ENST00000253407.4	C1QL1 Links Ensembl NCBI GeneCards UniProt Show fit	complement C1q like 1
chr12_-_262828 Show fit	3.25	ENST00000343164.9 ENST00000436453.1 ENST00000445055.6 ENST00000546319.5	SLC6A13 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 13
chr19_+_39342396 Show fit	3.25	ENST00000602243.5 ENST00000598913.5 ENST00000314471.10	SAMD4B Links Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 4B
chr12_-_102197827 Show fit	3.24	ENST00000329406.5	PMCH Links Ensembl NCBI GeneCards UniProt Show fit	pro-melanin concentrating hormone
chrX_-_130385656 Show fit	3.09	ENST00000276218.4 ENST00000682440.1	GPR119 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 119
chr17_-_8152380 Show fit	3.08	ENST00000317276.9	PER1 Links Ensembl NCBI GeneCards UniProt Show fit	period circadian regulator 1
chr22_+_38057200 Show fit	3.02	ENST00000404072.7 ENST00000424694.5	PICK1 Links Ensembl NCBI GeneCards UniProt Show fit	protein interacting with PRKCA 1
chr6_+_147508645 Show fit	3.00	ENST00000367474.2	SAMD5 Links Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 5
chr14_-_106389858 Show fit	2.99	ENST00000390617.2	IGHV3-35 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-35 (non-functional)
chr11_-_19202004 Show fit	2.97	ENST00000648719.1	CSRP3 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 3
chr11_-_132943092 Show fit	2.95	ENST00000612177.4 ENST00000541867.5	OPCML Links Ensembl NCBI GeneCards UniProt Show fit	opioid binding protein/cell adhesion molecule like
chr5_-_176629943 Show fit	2.86	ENST00000510387.5 ENST00000506696.1	SNCB Links Ensembl NCBI GeneCards UniProt Show fit	synuclein beta
chr14_-_106335613 Show fit	2.86	ENST00000603660.1	IGHV3-30 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-30
chr14_+_58427385 Show fit	2.83	ENST00000354386.10 ENST00000619416.4	KIAA0586 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0586
chr20_-_17558811 Show fit	2.82	ENST00000536626.7 ENST00000377868.6	BFSP1 Links Ensembl NCBI GeneCards UniProt Show fit	beaded filament structural protein 1
chr13_-_46390042 Show fit	2.78	ENST00000389908.7	RUBCNL Links Ensembl NCBI GeneCards UniProt Show fit	rubicon like autophagy enhancer
chr4_+_71062642 Show fit	2.78	ENST00000649996.1	SLC4A4 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 member 4
chr14_+_58427425 Show fit	2.75	ENST00000619722.5 ENST00000423743.7	KIAA0586 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0586
chr4_+_143381939 Show fit	2.70	ENST00000505913.5	GAB1 Links Ensembl NCBI GeneCards UniProt Show fit	GRB2 associated binding protein 1
chr14_-_106130061 Show fit	2.67	ENST00000390602.3	IGHV3-13 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-13
chr3_+_111998915 Show fit	2.65	ENST00000478951.6	TAGLN3 Links Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chr4_-_152679984 Show fit	2.64	ENST00000304385.8 ENST00000504064.1	TMEM154 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 154
chr11_-_19201976 Show fit	2.63	ENST00000647990.1 ENST00000649235.1 ENST00000265968.9 ENST00000649842.1	CSRP3 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 3
chr15_+_51681483 Show fit	2.62	ENST00000542355.6 ENST00000220478.8 ENST00000558709.1	SCG3 Links Ensembl NCBI GeneCards UniProt Show fit	secretogranin III
chr16_+_58392391 Show fit	2.56	ENST00000426538.6 ENST00000328514.11	GINS3 Links Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 3
chr17_-_44911281 Show fit	2.54	ENST00000638304.1 ENST00000591880.2 ENST00000586125.2 ENST00000639921.1	GFAP Links Ensembl NCBI GeneCards UniProt Show fit	glial fibrillary acidic protein
chr5_+_77086682 Show fit	2.53	ENST00000643365.1 ENST00000645183.1 ENST00000645374.1 ENST00000647364.1 ENST00000643848.1 ENST00000643603.1 ENST00000645459.1 ENST00000643269.1 ENST00000503969.6 ENST00000646262.1	ZBED3-AS1 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000284762.1 Links Ensembl NCBI GeneCards UniProt Show fit	ZBED3 antisense RNA 1 phosphodiesterase 8B
chr1_-_94541636 Show fit	2.53	ENST00000370207.4	F3 Links Ensembl NCBI GeneCards UniProt Show fit	coagulation factor III, tissue factor
chr17_-_9905248 Show fit	2.47	ENST00000226193.6	RCVRN Links Ensembl NCBI GeneCards UniProt Show fit	recoverin
chr11_-_132943671 Show fit	2.46	ENST00000331898.11	OPCML Links Ensembl NCBI GeneCards UniProt Show fit	opioid binding protein/cell adhesion molecule like
chr9_-_21202205 Show fit	2.45	ENST00000239347.3	IFNA7 Links Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 7
chr17_-_7204502 Show fit	2.39	ENST00000486626.8 ENST00000648263.1	DLG4 Links Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 4
chr12_-_56360084 Show fit	2.34	ENST00000314128.9 ENST00000557235.5 ENST00000651915.1	STAT2 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 2
chr17_-_15260752 Show fit	2.33	ENST00000676329.1 ENST00000675551.1 ENST00000644020.1 ENST00000674947.1	PMP22 Links Ensembl NCBI GeneCards UniProt Show fit	peripheral myelin protein 22
chr2_-_218671975 Show fit	2.27	ENST00000295704.7	RNF25 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 25
chr3_+_39051990 Show fit	2.26	ENST00000302313.10	WDR48 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 48
chr22_-_30529163 Show fit	2.24	ENST00000437871.1	SEC14L6 Links Ensembl NCBI GeneCards UniProt Show fit	SEC14 like lipid binding 6
chr17_-_3691887 Show fit	2.22	ENST00000552050.5	P2RX5 Links Ensembl NCBI GeneCards UniProt Show fit	purinergic receptor P2X 5
chr17_-_78782257 Show fit	2.22	ENST00000591455.5 ENST00000446868.7 ENST00000361101.8 ENST00000589296.5	CYTH1 Links Ensembl NCBI GeneCards UniProt Show fit	cytohesin 1
chr10_-_15719885 Show fit	2.21	ENST00000378076.4	ITGA8 Links Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 8
chr3_-_52454032 Show fit	2.21	ENST00000232975.8	TNNC1 Links Ensembl NCBI GeneCards UniProt Show fit	troponin C1, slow skeletal and cardiac type
chr8_+_42338454 Show fit	2.20	ENST00000532157.5 ENST00000520008.5	POLB Links Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase beta
chr11_-_17476801 Show fit	2.18	ENST00000644772.1 ENST00000642271.1 ENST00000684571.1 ENST00000646902.1 ENST00000647015.1 ENST00000302539.9 ENST00000389817.8 ENST00000643260.1 ENST00000683136.1	ABCC8 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily C member 8
chr16_+_28863812 Show fit	2.16	ENST00000684370.1	SH2B1 Links Ensembl NCBI GeneCards UniProt Show fit	SH2B adaptor protein 1
chr16_+_58392462 Show fit	2.15	ENST00000318129.6	GINS3 Links Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 3
chr6_+_28525877 Show fit	2.09	ENST00000412168.7	GPX5 Links Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 5
chr6_-_32763466 Show fit	2.07	ENST00000427449.1 ENST00000411527.5	HLA-DQB2 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ beta 2
chr14_+_58427970 Show fit	2.07	ENST00000261244.9	KIAA0586 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0586
chrX_+_48823357 Show fit	2.05	ENST00000430858.1	HDAC6 Links Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 6
chr22_+_32357867 Show fit	2.05	ENST00000249007.4	RFPL3 Links Ensembl NCBI GeneCards UniProt Show fit	ret finger protein like 3
chr6_-_32666648 Show fit	1.99	ENST00000399082.7 ENST00000399079.7 ENST00000374943.8 ENST00000434651.6	HLA-DQB1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ beta 1
chr10_+_116545907 Show fit	1.98	ENST00000369221.2	PNLIP Links Ensembl NCBI GeneCards UniProt Show fit	pancreatic lipase
chr17_+_60677822 Show fit	1.93	ENST00000407086.8 ENST00000589222.5 ENST00000626960.2 ENST00000390652.9	BCAS3 Links Ensembl NCBI GeneCards UniProt Show fit	BCAS3 microtubule associated cell migration factor
chr3_-_56468346 Show fit	1.86	ENST00000288221.11	ERC2 Links Ensembl NCBI GeneCards UniProt Show fit	ELKS/RAB6-interacting/CAST family member 2
chr12_-_49110840 Show fit	1.85	ENST00000550137.5 ENST00000267102.13 ENST00000547382.5	LMBR1L Links Ensembl NCBI GeneCards UniProt Show fit	limb development membrane protein 1 like
chr5_+_141094595 Show fit	1.83	ENST00000622947.1 ENST00000194155.7 ENST00000624874.1 ENST00000625033.1	PCDHB2 Links Ensembl NCBI GeneCards UniProt Show fit	protocadherin beta 2
chr16_-_20669855 Show fit	1.83	ENST00000524149.5	ACSM1 Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 1
chr14_-_55027045 Show fit	1.81	ENST00000455555.1 ENST00000360586.8 ENST00000420358.2	WDHD1 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat and HMG-box DNA binding protein 1
chr16_+_28863757 Show fit	1.81	ENST00000618521.4 ENST00000359285.9 ENST00000538342.5	SH2B1 Links Ensembl NCBI GeneCards UniProt Show fit	SH2B adaptor protein 1
chr16_-_66918839 Show fit	1.79	ENST00000565235.2 ENST00000568632.5 ENST00000565796.5	CDH16 Links Ensembl NCBI GeneCards UniProt Show fit	cadherin 16
chr14_+_58427686 Show fit	1.79	ENST00000650904.1 ENST00000652326.2 ENST00000554463.5 ENST00000555833.5	KIAA0586 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0586
chr12_+_7789393 Show fit	1.78	ENST00000229307.9	NANOG Links Ensembl NCBI GeneCards UniProt Show fit	Nanog homeobox
chr5_+_96936071 Show fit	1.78	ENST00000231368.10	LNPEP Links Ensembl NCBI GeneCards UniProt Show fit	leucyl and cystinyl aminopeptidase
chr1_+_154429315 Show fit	1.76	ENST00000476006.5	IL6R Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 receptor
chr1_+_173824626 Show fit	1.75	ENST00000648960.1 ENST00000648807.1 ENST00000649067.1 ENST00000649689.2	DARS2 Links Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 2, mitochondrial
chr16_-_66918876 Show fit	1.75	ENST00000570262.5 ENST00000299752.9 ENST00000394055.7	CDH16 Links Ensembl NCBI GeneCards UniProt Show fit	cadherin 16
chr20_+_63738270 Show fit	1.74	ENST00000467211.1	ENSG00000273047.1 Links Ensembl NCBI GeneCards UniProt Show fit	novel transcript, LIME1-SLC2A4RG readthrough
chr14_-_106360320 Show fit	1.72	ENST00000390615.2	IGHV3-33 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-33
chr6_+_41042557 Show fit	1.72	ENST00000373158.6 ENST00000470917.1	TSPO2 Links Ensembl NCBI GeneCards UniProt Show fit	translocator protein 2
chr16_+_32995048 Show fit	1.72	ENST00000425181.3	IGHV3OR16-10 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr2_+_79025709 Show fit	1.70	ENST00000409471.1	REG3G Links Ensembl NCBI GeneCards UniProt Show fit	regenerating family member 3 gamma
chr21_-_34615103 Show fit	1.68	ENST00000313806.9	RCAN1 Links Ensembl NCBI GeneCards UniProt Show fit	regulator of calcineurin 1
chr14_-_24263162 Show fit	1.62	ENST00000206765.11 ENST00000544573.5	TGM1 Links Ensembl NCBI GeneCards UniProt Show fit	transglutaminase 1
chr3_+_138010143 Show fit	1.60	ENST00000183605.10	CLDN18 Links Ensembl NCBI GeneCards UniProt Show fit	claudin 18
chr3_-_109118131 Show fit	1.51	ENST00000232603.10	MORC1 Links Ensembl NCBI GeneCards UniProt Show fit	MORC family CW-type zinc finger 1
chr1_+_173824694 Show fit	1.51	ENST00000647645.1	DARS2 Links Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 2, mitochondrial
chr9_-_21141832 Show fit	1.50	ENST00000380229.4	IFNW1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon omega 1
chr19_-_43754901 Show fit	1.49	ENST00000270066.11 ENST00000601170.5	SMG9 Links Ensembl NCBI GeneCards UniProt Show fit	SMG9 nonsense mediated mRNA decay factor
chr22_+_38705922 Show fit	1.47	ENST00000216044.10	GTPBP1 Links Ensembl NCBI GeneCards UniProt Show fit	GTP binding protein 1
chr4_+_177309866 Show fit	1.45	ENST00000264596.4	NEIL3 Links Ensembl NCBI GeneCards UniProt Show fit	nei like DNA glycosylase 3
chr6_+_99606833 Show fit	1.43	ENST00000369215.5	PRDM13 Links Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 13
chr19_-_11236497 Show fit	1.43	ENST00000587656.5	DOCK6 Links Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 6
chr7_+_87345656 Show fit	1.42	ENST00000331536.8 ENST00000419147.6 ENST00000412227.6	CROT Links Ensembl NCBI GeneCards UniProt Show fit	carnitine O-octanoyltransferase
chr12_-_24562438 Show fit	1.38	ENST00000646273.1 ENST00000659413.1 ENST00000446891.7	SOX5 Links Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 5
chr3_+_186666003 Show fit	1.38	ENST00000232003.5	HRG Links Ensembl NCBI GeneCards UniProt Show fit	histidine rich glycoprotein
chr14_-_36521149 Show fit	1.38	ENST00000518149.5	NKX2-1 Links Ensembl NCBI GeneCards UniProt Show fit	NK2 homeobox 1
chr19_-_33225844 Show fit	1.36	ENST00000253188.8	SLC7A10 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 10
chr10_-_77637721 Show fit	1.35	ENST00000638848.1 ENST00000639406.1 ENST00000618048.2 ENST00000639120.1 ENST00000640834.1 ENST00000639601.1 ENST00000638514.1 ENST00000457953.6 ENST00000639090.1 ENST00000639489.1 ENST00000372440.6 ENST00000404771.8 ENST00000638203.1 ENST00000638306.1 ENST00000638351.1 ENST00000638606.1 ENST00000639591.1 ENST00000640182.1 ENST00000640605.1 ENST00000640141.1	KCNMA1 Links Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M alpha 1
chrX_-_32155462 Show fit	1.35	ENST00000359836.5 ENST00000378707.7 ENST00000541735.5 ENST00000684130.1 ENST00000682238.1 ENST00000620040.5 ENST00000474231.5	DMD Links Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr16_+_33827140 Show fit	1.32	ENST00000562905.2	IGHV3OR16-13 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr13_-_46182136 Show fit	1.30	ENST00000323076.7	LCP1 Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte cytosolic protein 1
chr11_-_107719657 Show fit	1.28	ENST00000525934.1 ENST00000531293.1	SLN Links Ensembl NCBI GeneCards UniProt Show fit	sarcolipin
chr7_-_95396349 Show fit	1.26	ENST00000427422.5 ENST00000451904.5 ENST00000265627.10	PON3 Links Ensembl NCBI GeneCards UniProt Show fit	paraoxonase 3
chr2_+_79025678 Show fit	1.26	ENST00000393897.6	REG3G Links Ensembl NCBI GeneCards UniProt Show fit	regenerating family member 3 gamma
chrX_-_64976435 Show fit	1.26	ENST00000374839.8	ZC4H2 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger C4H2-type containing
chr12_-_8066331 Show fit	1.17	ENST00000546241.1 ENST00000307637.5	C3AR1 Links Ensembl NCBI GeneCards UniProt Show fit	complement C3a receptor 1
chr12_-_84892120 Show fit	1.12	ENST00000680379.1	SLC6A15 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 15
chr14_-_23155302 Show fit	1.11	ENST00000529705.6	SLC7A8 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 8
chr14_+_58298497 Show fit	1.09	ENST00000348476.7 ENST00000355431.8 ENST00000395168.7	ARID4A Links Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 4A
chr18_+_45724127 Show fit	1.08	ENST00000619403.4 ENST00000587601.5	SLC14A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 14 member 1 (Kidd blood group)
chr6_+_52186373 Show fit	1.01	ENST00000648244.1	IL17A Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 17A
chr3_-_179266971 Show fit	1.00	ENST00000349697.2 ENST00000497599.5	KCNMB3 Links Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr2_+_79025696 Show fit	1.00	ENST00000272324.10	REG3G Links Ensembl NCBI GeneCards UniProt Show fit	regenerating family member 3 gamma
chr5_-_181261078 Show fit	0.98	ENST00000611618.1	TRIM52 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 52
chr11_-_72080680 Show fit	0.98	ENST00000613205.4	NUMA1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear mitotic apparatus protein 1
chr4_+_89894846 Show fit	0.96	ENST00000264790.7	MMRN1 Links Ensembl NCBI GeneCards UniProt Show fit	multimerin 1
chr19_-_4559663 Show fit	0.92	ENST00000586582.6	SEMA6B Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6B
chr12_-_12684490 Show fit	0.92	ENST00000540510.1	GPR19 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 19
chr6_-_131951364 Show fit	0.89	ENST00000367976.4	CCN2 Links Ensembl NCBI GeneCards UniProt Show fit	cellular communication network factor 2
chr20_-_45308297 Show fit	0.89	ENST00000353917.10 ENST00000360607.10	MATN4 Links Ensembl NCBI GeneCards UniProt Show fit	matrilin 4
chr9_-_22009272 Show fit	0.87	ENST00000380142.5 ENST00000276925.7	CDKN2B Links Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 2B
chrX_-_70260199 Show fit	0.87	ENST00000374519.4	P2RY4 Links Ensembl NCBI GeneCards UniProt Show fit	pyrimidinergic receptor P2Y4
chrX_-_31178220 Show fit	0.84	ENST00000681026.1	DMD Links Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr10_-_77637789 Show fit	0.83	ENST00000481070.1 ENST00000640969.1 ENST00000286628.14 ENST00000638991.1 ENST00000639913.1 ENST00000480683.2	KCNMA1 Links Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M alpha 1
chrX_+_153687918 Show fit	0.82	ENST00000253122.10	SLC6A8 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 8
chrX_-_11265975 Show fit	0.81	ENST00000303025.10 ENST00000657361.1	ARHGAP6 Links Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 6
chr11_+_121129964 Show fit	0.79	ENST00000645008.1	TECTA Links Ensembl NCBI GeneCards UniProt Show fit	tectorin alpha
chr6_+_69232406 Show fit	0.79	ENST00000238918.12	ADGRB3 Links Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor B3
chr22_+_20858999 Show fit	0.77	ENST00000215730.12	SNAP29 Links Ensembl NCBI GeneCards UniProt Show fit	synaptosome associated protein 29
chr8_+_97887903 Show fit	0.71	ENST00000520016.5	MATN2 Links Ensembl NCBI GeneCards UniProt Show fit	matrilin 2
chr2_+_227616998 Show fit	0.70	ENST00000641801.1	SCYGR4 Links Ensembl NCBI GeneCards UniProt Show fit	small cysteine and glycine repeat containing 4
chr9_-_21385395 Show fit	0.67	ENST00000380206.4	IFNA2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 2
chr2_+_203936755 Show fit	0.64	ENST00000316386.11 ENST00000435193.1	ICOS Links Ensembl NCBI GeneCards UniProt Show fit	inducible T cell costimulator
chr9_-_14322320 Show fit	0.63	ENST00000606230.2	NFIB Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr12_+_56996151 Show fit	0.60	ENST00000556850.1	GPR182 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 182
chr12_+_120978686 Show fit	0.59	ENST00000541395.5 ENST00000544413.2	HNF1A Links Ensembl NCBI GeneCards UniProt Show fit	HNF1 homeobox A
chrX_-_31178149 Show fit	0.58	ENST00000679437.1	DMD Links Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr10_-_99913971 Show fit	0.57	ENST00000543621.6	DNMBP Links Ensembl NCBI GeneCards UniProt Show fit	dynamin binding protein
chr17_+_48107549 Show fit	0.55	ENST00000580219.5 ENST00000452859.6 ENST00000393405.6	SNX11 Links Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 11
chr6_-_70303070 Show fit	0.53	ENST00000370496.3 ENST00000357250.11	COL9A1 Links Ensembl NCBI GeneCards UniProt Show fit	collagen type IX alpha 1 chain
chr7_-_157010615 Show fit	0.51	ENST00000252971.11	MNX1 Links Ensembl NCBI GeneCards UniProt Show fit	motor neuron and pancreas homeobox 1
chr5_+_69369781 Show fit	0.49	ENST00000509734.5 ENST00000354868.10 ENST00000521422.5 ENST00000354312.7 ENST00000345306.10	RAD17 Links Ensembl NCBI GeneCards UniProt Show fit	RAD17 checkpoint clamp loader component
chr2_+_27496830 Show fit	0.48	ENST00000264717.7	GCKR Links Ensembl NCBI GeneCards UniProt Show fit	glucokinase regulator
chr2_+_232633551 Show fit	0.47	ENST00000264059.8	EFHD1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain family member D1
chr2_-_166149120 Show fit	0.46	ENST00000641575.1 ENST00000641603.1	SCN1A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 1
chr17_+_78214286 Show fit	0.43	ENST00000592734.5 ENST00000587746.5	BIRC5 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 5
chr16_+_22490337 Show fit	0.42	ENST00000415833.6	NPIPB5 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear pore complex interacting protein family member B5
chr1_+_16022030 Show fit	0.39	ENST00000331433.5	CLCNKA Links Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel Ka
chr22_+_17638584 Show fit	0.38	ENST00000337612.9 ENST00000418951.6 ENST00000538149.5 ENST00000543133.5 ENST00000611738.4 ENST00000616863.4 ENST00000618481.4 ENST00000317582.10 ENST00000493680.5	BCL2L13 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2 like 13
chr1_+_149899618 Show fit	0.38	ENST00000369150.1	BOLA1 Links Ensembl NCBI GeneCards UniProt Show fit	bolA family member 1
chr3_-_134250831 Show fit	0.37	ENST00000623711.4	RYK Links Ensembl NCBI GeneCards UniProt Show fit	receptor like tyrosine kinase
chr22_-_36817510 Show fit	0.35	ENST00000443735.1	PVALB Links Ensembl NCBI GeneCards UniProt Show fit	parvalbumin

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	6.7	GO:0036292	DNA rewinding(GO:0036292)
2.2	8.8	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
1.6	30.5	GO:0042424	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
1.3	4.0	GO:0044278	cell wall disruption in other organism(GO:0044278)
1.2	3.6	GO:0016476	regulation of embryonic cell shape(GO:0016476) glomerular visceral epithelial cell migration(GO:0090521)
1.2	22.3	GO:0015671	oxygen transport(GO:0015671)
1.2	3.5	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
1.1	5.6	GO:0035995	detection of muscle stretch(GO:0035995)
1.1	3.3	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
1.1	79.2	GO:0006910	phagocytosis, recognition(GO:0006910)
1.0	4.1	GO:0099558	maintenance of synapse structure(GO:0099558)
0.7	2.2	GO:0002086	diaphragm contraction(GO:0002086)
0.7	2.2	GO:1905071	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.7	2.1	GO:0070844	misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.7	8.7	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.6	2.5	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.6	3.1	GO:0097167	circadian regulation of translation(GO:0097167)
0.6	1.8	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.5	5.5	GO:0097113	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.4	1.8	GO:0002384	hepatic immune response(GO:0002384)
0.4	1.3	GO:1901877	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.4	1.3	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.4	6.1	GO:0006600	creatine metabolic process(GO:0006600)
0.4	1.6	GO:0006288	base-excision repair, DNA ligation(GO:0006288)
0.4	3.0	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3	1.4	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.3	1.4	GO:0021759	globus pallidus development(GO:0021759)
0.3	1.0	GO:0071988	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.3	3.5	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.3	0.6	GO:0035565	regulation of pronephros size(GO:0035565)
0.3	15.2	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.3	1.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.3	1.5	GO:0044026	DNA hypermethylation(GO:0044026)
0.2	1.4	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.2	3.6	GO:0051775	response to redox state(GO:0051775)
0.2	2.3	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.2	21.8	GO:0006958	complement activation, classical pathway(GO:0006958)
0.2	1.1	GO:0035524	proline transmembrane transport(GO:0035524)
0.2	1.8	GO:0001714	endodermal cell fate specification(GO:0001714)
0.2	1.1	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.2	2.8	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2	1.0	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.2	2.8	GO:0070307	lens fiber cell development(GO:0070307)
0.2	1.6	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.2	1.4	GO:0032328	alanine transport(GO:0032328)
0.2	4.7	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.2	3.5	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.2	9.3	GO:0018149	peptide cross-linking(GO:0018149)
0.2	2.2	GO:0034465	response to carbon monoxide(GO:0034465)
0.2	1.8	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2	2.5	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.2	4.6	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2	0.8	GO:0016240	autophagosome docking(GO:0016240)
0.1	3.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.1	5.4	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	2.0	GO:0002455	humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.1	2.0	GO:0098856	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1	1.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	1.4	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.1	2.5	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	2.7	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.1	3.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	5.1	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.1	3.1	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1	5.4	GO:0008038	neuron recognition(GO:0008038)
0.1	2.0	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.1	0.3	GO:2001226	negative regulation of chloride transport(GO:2001226)
0.1	0.4	GO:0061643	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.1	2.7	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.1	4.9	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	5.2	GO:0019228	neuronal action potential(GO:0019228)
0.1	0.7	GO:2000662	negative regulation of interleukin-13 production(GO:0032696) interleukin-5 secretion(GO:0072603) regulation of interleukin-5 secretion(GO:2000662)
0.1	0.5	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	2.9	GO:0042417	dopamine metabolic process(GO:0042417)
0.1	1.3	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	0.5	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	1.5	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.1	2.3	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.1	0.3	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	9.4	GO:0007224	smoothened signaling pathway(GO:0007224)
0.1	4.0	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
0.1	3.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1	2.8	GO:0015701	bicarbonate transport(GO:0015701)
0.0	1.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.2	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	4.2	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.6	GO:0002517	T cell tolerance induction(GO:0002517)
0.0	3.6	GO:0030239	myofibril assembly(GO:0030239)
0.0	1.7	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	2.6	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	1.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.2	GO:0070305	response to cGMP(GO:0070305)
0.0	0.2	GO:0002457	T cell antigen processing and presentation(GO:0002457) dsRNA transport(GO:0033227)
0.0	10.3	GO:0006869	lipid transport(GO:0006869)
0.0	4.3	GO:0001508	action potential(GO:0001508)
0.0	2.2	GO:0007422	peripheral nervous system development(GO:0007422)
0.0	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.3	GO:0097320	membrane tubulation(GO:0097320)
0.0	1.8	GO:0098869	cellular oxidant detoxification(GO:0098869)
0.0	4.2	GO:0060271	cilium morphogenesis(GO:0060271)
0.0	2.1	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	5.7	GO:0002250	adaptive immune response(GO:0002250)
0.0	0.7	GO:0031102	neuron projection regeneration(GO:0031102)
0.0	1.9	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0	0.2	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.8	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	1.2	GO:0007286	spermatid development(GO:0007286)
0.0	1.5	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	3.3	GO:0006457	protein folding(GO:0006457)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.5	18.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
3.8	11.3	GO:0071756	IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
1.4	67.9	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.6	2.2	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
0.4	5.8	GO:0098839	postsynaptic density membrane(GO:0098839)
0.4	2.2	GO:1990584	cardiac Troponin complex(GO:1990584)
0.4	1.8	GO:0031905	early endosome lumen(GO:0031905)
0.4	1.8	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.3	4.3	GO:0005833	hemoglobin complex(GO:0005833)
0.3	1.0	GO:0055028	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
0.3	4.1	GO:0043083	synaptic cleft(GO:0043083)
0.3	2.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	4.3	GO:0005922	connexon complex(GO:0005922)
0.2	2.8	GO:0016013	syntrophin complex(GO:0016013)
0.2	4.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	9.3	GO:0001533	cornified envelope(GO:0001533)
0.2	2.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.2	9.4	GO:0001917	photoreceptor inner segment(GO:0001917)
0.2	3.6	GO:0044447	axoneme part(GO:0044447)
0.2	4.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.2	3.5	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	6.7	GO:0043596	nuclear replication fork(GO:0043596)
0.1	0.8	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1	3.6	GO:0031143	pseudopodium(GO:0031143)
0.1	13.6	GO:0042734	presynaptic membrane(GO:0042734)
0.1	0.5	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	1.9	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	2.3	GO:0043218	compact myelin(GO:0043218)
0.1	1.5	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.1	2.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	1.3	GO:0001891	phagocytic cup(GO:0001891)
0.1	2.1	GO:0030286	dynein complex(GO:0030286)
0.0	4.3	GO:0036064	ciliary basal body(GO:0036064)
0.0	6.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	5.2	GO:0005882	intermediate filament(GO:0005882)
0.0	4.0	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	11.5	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.5	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	3.2	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	1.4	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	4.0	GO:0072562	blood microparticle(GO:0072562)
0.0	3.2	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	1.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	1.6	GO:0005876	spindle microtubule(GO:0005876)
0.0	1.2	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	2.4	GO:0016605	PML body(GO:0016605)
0.0	0.8	GO:0034707	chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.4	30.5	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
1.5	22.3	GO:0005344	oxygen transporter activity(GO:0005344)
1.3	79.2	GO:0034987	immunoglobulin receptor binding(GO:0034987)
1.2	3.7	GO:0032093	SAM domain binding(GO:0032093)
0.8	9.2	GO:0031433	telethonin binding(GO:0031433)
0.7	8.8	GO:0030911	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.7	5.8	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.7	5.3	GO:0004111	creatine kinase activity(GO:0004111)
0.6	1.9	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.6	7.7	GO:0030280	structural constituent of epidermis(GO:0030280)
0.6	6.7	GO:0036310	annealing helicase activity(GO:0036310)
0.6	3.5	GO:0061665	SUMO ligase activity(GO:0061665)
0.6	1.8	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
0.5	2.2	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.5	3.5	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.5	2.5	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.4	2.1	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.4	3.3	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4	4.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.4	3.0	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.4	1.1	GO:0015265	urea channel activity(GO:0015265)
0.3	1.3	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.3	3.5	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.3	4.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.3	4.3	GO:0005243	gap junction channel activity(GO:0005243)
0.2	5.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.2	2.2	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.2	1.6	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2	1.1	GO:0005298	proline:sodium symporter activity(GO:0005298)
0.2	1.4	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.2	2.2	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2	2.9	GO:1903136	cuprous ion binding(GO:1903136)
0.2	1.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2	1.8	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.2	30.8	GO:0003823	antigen binding(GO:0003823)
0.2	3.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2	2.2	GO:0031014	troponin T binding(GO:0031014)
0.1	4.9	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	3.3	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1	2.8	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.9	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	4.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	0.5	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.1	1.4	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	2.8	GO:0050998	dystroglycan binding(GO:0002162) nitric-oxide synthase binding(GO:0050998)
0.1	3.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	1.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	1.0	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	2.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	3.2	GO:0030371	translation repressor activity(GO:0030371)
0.1	1.4	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1	10.3	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1	15.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	1.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	1.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.5	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	3.6	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	0.9	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	2.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	2.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.9	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.4	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1	0.5	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	3.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.8	GO:0072349	modified amino acid transmembrane transporter activity(GO:0072349)
0.0	2.7	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	1.0	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	1.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	1.7	GO:0015485	cholesterol binding(GO:0015485)
0.0	7.3	GO:0051015	actin filament binding(GO:0051015)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	1.1	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.3	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	3.0	GO:0005179	hormone activity(GO:0005179)
0.0	0.3	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.0	1.4	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.8	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.4	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	2.5	GO:0002020	protease binding(GO:0002020)
0.0	0.6	GO:0046934	phosphatidylinositol 3-kinase activity(GO:0035004) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.2	2.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.2	3.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	1.8	ST STAT3 PATHWAY	STAT3 Pathway
0.1	3.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	5.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	2.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	6.7	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	3.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	2.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	8.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	2.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	2.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.8	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.7	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	3.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.5	NABA COLLAGENS	Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	10.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.2	4.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	9.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	3.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.2	1.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	4.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	6.7	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	6.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.8	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	2.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	3.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	2.7	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	2.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	5.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.0	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	2.5	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	2.1	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1	2.5	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	1.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.8	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.9	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	1.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	5.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.9	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	2.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	4.9	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	4.7	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	2.8	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.9	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.6	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress