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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NKX3-1

Z-value: 2.63

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Transcription factors associated with NKX3-1

Gene Symbol Gene ID Gene Info
NKX3-1
ENSG00000167034.10 NKX3-1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-1hg38_v1_chr8_-_23682889_23682951-0.243.0e-04Click!

Activity profile of NKX3-1 motif

Sorted Z-values of NKX3-1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_150487658 11.91 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
RND3
Rho family GTPase 3
chr6_+_24775413 11.23 ENST00000378054.6
ENST00000620958.4
ENST00000476555.5
GMNN
geminin DNA replication inhibitor
chr16_+_3018390 10.94 ENST00000573001.5
TNFRSF12A
TNF receptor superfamily member 12A
chr16_-_69726506 10.26 ENST00000561500.5
ENST00000320623.10
ENST00000439109.6
ENST00000564043.1
ENST00000379046.6
ENST00000379047.7
NQO1
NAD(P)H quinone dehydrogenase 1
chrX_+_115561162 9.88 ENST00000355899.8
ENST00000626746.2
ENST00000289290.7
PLS3
plastin 3
chr3_-_81761636 9.57 ENST00000429644.7
GBE1
1,4-alpha-glucan branching enzyme 1
chr2_-_27323072 9.23 ENST00000428910.5
ENST00000402722.5
ENST00000380044.6
ENST00000399052.8
ENST00000405076.5
MPV17
mitochondrial inner membrane protein MPV17
chr1_-_6385783 8.64 ENST00000377855.6
ACOT7
acyl-CoA thioesterase 7
chr9_+_36572854 8.53 ENST00000543751.5
ENST00000536860.5
ENST00000541717.4
ENST00000536329.5
ENST00000536987.5
ENST00000298048.7
ENST00000495529.5
ENST00000545008.5
MELK
maternal embryonic leucine zipper kinase
chr5_-_43412323 8.10 ENST00000361115.4
CCL28
C-C motif chemokine ligand 28
chr7_+_16661182 7.82 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
BZW2
basic leucine zipper and W2 domains 2
chr3_+_160399630 7.31 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
SMC4
structural maintenance of chromosomes 4
chr10_-_73252601 7.20 ENST00000372945.8
ENST00000372940.3
MRPS16
mitochondrial ribosomal protein S16
chr18_-_36798482 7.13 ENST00000590258.2
TPGS2
tubulin polyglutamylase complex subunit 2
chr11_+_57805541 7.12 ENST00000683201.1
ENST00000683769.1
CTNND1
catenin delta 1
chr2_+_101839815 6.27 ENST00000421882.5
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr9_-_14180779 6.12 ENST00000380924.1
ENST00000543693.5
NFIB
nuclear factor I B
chr3_-_42875871 5.50 ENST00000316161.6
ENST00000437102.1
CYP8B1
cytochrome P450 family 8 subfamily B member 1
chr1_+_151399557 5.45 ENST00000290541.7
PSMB4
proteasome 20S subunit beta 4
chr6_-_53510445 5.22 ENST00000509541.5
GCLC
glutamate-cysteine ligase catalytic subunit
chr18_+_2571529 5.09 ENST00000261597.9
ENST00000575515.1
NDC80
NDC80 kinetochore complex component
chr11_+_102112445 5.03 ENST00000524575.5
YAP1
Yes1 associated transcriptional regulator
chr16_-_66830903 5.02 ENST00000566336.5
ENST00000394074.6
ENST00000563185.6
ENST00000359087.8
ENST00000290810.8
ENST00000379463.6
ENST00000565535.5
NAE1
NEDD8 activating enzyme E1 subunit 1
chr7_+_80135694 4.79 ENST00000457358.7
GNAI1
G protein subunit alpha i1
chr3_+_159273235 4.68 ENST00000638749.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr20_+_19886506 4.55 ENST00000648440.1
RIN2
Ras and Rab interactor 2
chr3_+_100709424 4.45 ENST00000675246.1
ENST00000675692.1
ENST00000675890.1
ENST00000675586.1
ENST00000674645.1
ENST00000675958.1
ENST00000479672.6
ENST00000675420.1
ENST00000674615.1
ENST00000676431.1
ENST00000674758.1
TFG
trafficking from ER to golgi regulator
chr6_+_150683593 4.35 ENST00000644968.1
PLEKHG1
pleckstrin homology and RhoGEF domain containing G1
chr17_-_78874038 4.33 ENST00000586057.5
TIMP2
TIMP metallopeptidase inhibitor 2
chr8_-_48921419 4.27 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr2_-_27323006 4.27 ENST00000402310.5
ENST00000405983.5
ENST00000403262.6
MPV17
mitochondrial inner membrane protein MPV17
chr9_+_706841 4.23 ENST00000382293.7
KANK1
KN motif and ankyrin repeat domains 1
chr3_+_100709473 4.23 ENST00000240851.9
ENST00000675243.1
ENST00000676111.1
ENST00000476228.5
ENST00000463568.6
ENST00000676395.1
TFG
trafficking from ER to golgi regulator
chr1_-_74733253 4.12 ENST00000417775.5
CRYZ
crystallin zeta
chr17_-_78874140 4.11 ENST00000585421.5
TIMP2
TIMP metallopeptidase inhibitor 2
chr7_+_100706061 4.09 ENST00000303151.5
POP7
POP7 homolog, ribonuclease P/MRP subunit
chr5_+_177446445 4.07 ENST00000507881.5
PRR7
proline rich 7, synaptic
chr3_+_100709290 4.06 ENST00000675047.1
ENST00000490574.6
ENST00000675543.1
ENST00000676308.1
ENST00000675499.1
TFG
trafficking from ER to golgi regulator
chr7_-_7640971 4.00 ENST00000396682.6
RPA3
replication protein A3
chr2_+_63842325 3.94 ENST00000445915.6
ENST00000475462.5
UGP2
UDP-glucose pyrophosphorylase 2
chr2_+_63841882 3.76 ENST00000337130.10
ENST00000488245.6
UGP2
UDP-glucose pyrophosphorylase 2
chr5_-_177462379 3.76 ENST00000512501.1
DBN1
drebrin 1
chr7_+_135557904 3.73 ENST00000285968.11
NUP205
nucleoporin 205
chr3_+_100709344 3.72 ENST00000418917.7
ENST00000675553.1
TFG
trafficking from ER to golgi regulator
chr3_+_100709382 3.67 ENST00000620299.5
TFG
trafficking from ER to golgi regulator
chr13_+_114235044 3.55 ENST00000252457.9
ENST00000375308.5
CDC16
cell division cycle 16
chr3_+_139343996 3.45 ENST00000680020.1
ENST00000310776.9
ENST00000465373.5
MRPS22
mitochondrial ribosomal protein S22
chr17_+_35587478 3.29 ENST00000618940.4
AP2B1
adaptor related protein complex 2 subunit beta 1
chr11_+_65040895 3.17 ENST00000531072.1
ENST00000398846.6
SAC3D1
SAC3 domain containing 1
chr18_+_63476927 3.14 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
SERPINB5
serpin family B member 5
chr10_+_3104676 3.14 ENST00000415005.6
ENST00000468050.1
PFKP
phosphofructokinase, platelet
chr1_-_77219399 3.08 ENST00000359130.1
ENST00000370812.8
ENST00000445065.5
PIGK
phosphatidylinositol glycan anchor biosynthesis class K
chr3_-_177197429 3.02 ENST00000457928.7
TBL1XR1
TBL1X receptor 1
chr7_-_6826275 2.99 ENST00000316731.13
CCZ1B
CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated
chr12_+_95858928 2.93 ENST00000266735.9
ENST00000553192.5
ENST00000552085.1
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr8_+_30442602 2.92 ENST00000520191.5
RBPMS
RNA binding protein, mRNA processing factor
chr1_-_244862381 2.91 ENST00000640001.1
ENST00000639628.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U
chr14_-_70600643 2.89 ENST00000554963.5
ENST00000256379.10
ENST00000430055.6
ENST00000440435.2
ENST00000615788.4
MED6
mediator complex subunit 6
chr5_+_179698367 2.79 ENST00000680406.1
ENST00000502296.6
ENST00000504734.5
CANX
calnexin
chr2_-_197499857 2.79 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
HSPD1
heat shock protein family D (Hsp60) member 1
chr1_+_95151377 2.75 ENST00000604203.1
TLCD4-RWDD3
TLCD4-RWDD3 readthrough
chr12_+_12813316 2.68 ENST00000352940.8
ENST00000358007.7
ENST00000544400.1
DDX47
DEAD-box helicase 47
chr14_-_102362714 2.65 ENST00000536961.6
ENST00000541568.6
ENST00000216756.11
CINP
cyclin dependent kinase 2 interacting protein
chr10_-_32056376 2.64 ENST00000302418.5
KIF5B
kinesin family member 5B
chr17_+_82716698 2.63 ENST00000269373.11
ENST00000577128.1
ENST00000573158.5
FN3KRP
fructosamine 3 kinase related protein
chr18_+_63777773 2.63 ENST00000447428.5
ENST00000546027.5
SERPINB7
serpin family B member 7
chr17_+_35587239 2.60 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
AP2B1
adaptor related protein complex 2 subunit beta 1
chr11_+_65570452 2.43 ENST00000531405.5
ENST00000309328.8
ENST00000527920.5
ENST00000526877.1
ENST00000533115.5
ENST00000526433.1
ZNRD2
zinc ribbon domain containing 2
chr3_+_169966764 2.41 ENST00000337002.9
ENST00000480708.5
SEC62
SEC62 homolog, preprotein translocation factor
chr2_-_55269207 2.40 ENST00000263629.9
ENST00000403721.5
MTIF2
mitochondrial translational initiation factor 2
chr5_+_126423176 2.36 ENST00000542322.5
ENST00000544396.5
GRAMD2B
GRAM domain containing 2B
chr16_-_69339493 2.35 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
COG8
component of oligomeric golgi complex 8
chr10_-_103193252 2.30 ENST00000404739.8
ENST00000674860.1
ENST00000675645.1
ENST00000343289.9
NT5C2
5'-nucleotidase, cytosolic II
chr15_-_55270874 2.23 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A
RAB27A, member RAS oncogene family
chr6_+_43635832 2.20 ENST00000372171.5
MAD2L1BP
MAD2L1 binding protein
chr5_+_126423122 2.20 ENST00000515200.5
GRAMD2B
GRAM domain containing 2B
chr6_-_26123910 2.18 ENST00000314332.5
ENST00000396984.1
H2BC4
H2B clustered histone 4
chr8_-_38176674 2.17 ENST00000520755.5
LSM1
LSM1 homolog, mRNA degradation associated
chr8_-_96235533 2.15 ENST00000518406.5
ENST00000287022.10
ENST00000523920.1
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr8_+_32548210 2.07 ENST00000523079.5
ENST00000650919.1
NRG1
neuregulin 1
chr5_-_34915493 2.04 ENST00000382038.7
RAD1
RAD1 checkpoint DNA exonuclease
chr17_+_17179527 1.92 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chr3_+_98763331 1.91 ENST00000485391.5
ENST00000492254.5
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr15_+_99105071 1.89 ENST00000328642.11
ENST00000594047.2
ENST00000336292.11
SYNM
synemin
chr19_-_43670153 1.87 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
PLAUR
plasminogen activator, urokinase receptor
chr4_+_56977710 1.85 ENST00000450656.5
ENST00000381227.5
POLR2B
RNA polymerase II subunit B
chrX_-_154409246 1.85 ENST00000369807.6
DNASE1L1
deoxyribonuclease 1 like 1
chr21_-_25734887 1.80 ENST00000400094.5
ENST00000284971.8
ATP5PF
ATP synthase peripheral stalk subunit F6
chr4_-_102825854 1.76 ENST00000350435.11
UBE2D3
ubiquitin conjugating enzyme E2 D3
chrX_-_108438407 1.75 ENST00000334504.12
ENST00000621266.4
ENST00000538570.5
ENST00000394872.6
ENST00000545689.2
COL4A6
collagen type IV alpha 6 chain
chr22_+_41621977 1.75 ENST00000405506.2
XRCC6
X-ray repair cross complementing 6
chrX_-_154409278 1.70 ENST00000369808.7
DNASE1L1
deoxyribonuclease 1 like 1
chr5_+_141392616 1.67 ENST00000398604.3
PCDHGA8
protocadherin gamma subfamily A, 8
chr19_+_1026566 1.66 ENST00000562015.5
ENST00000263097.9
ENST00000348419.7
ENST00000565096.6
ENST00000562958.6
ENST00000568865.3
ENST00000606983.5
ENST00000562075.6
ENST00000607102.1
CNN2
calponin 2
chr17_+_68525795 1.64 ENST00000592800.5
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr8_-_61689768 1.64 ENST00000517847.6
ENST00000389204.8
ENST00000517661.5
ENST00000517903.5
ENST00000522603.5
ENST00000541428.5
ENST00000522349.5
ENST00000522835.5
ENST00000518306.5
ASPH
aspartate beta-hydroxylase
chr7_+_97117676 1.64 ENST00000432641.3
SDHAF3
succinate dehydrogenase complex assembly factor 3
chr4_-_102825526 1.62 ENST00000504211.5
ENST00000508476.5
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr10_+_91798398 1.59 ENST00000371627.5
TNKS2
tankyrase 2
chr7_-_120858066 1.59 ENST00000222747.8
TSPAN12
tetraspanin 12
chr6_-_159789660 1.58 ENST00000538128.5
ENST00000537390.5
ENST00000392168.6
TCP1
t-complex 1
chr6_+_26251607 1.56 ENST00000619466.2
H2BC9
H2B clustered histone 9
chr20_-_57710539 1.51 ENST00000395816.7
ENST00000347215.8
PMEPA1
prostate transmembrane protein, androgen induced 1
chr3_+_138608575 1.50 ENST00000338446.8
FAIM
Fas apoptotic inhibitory molecule
chrX_-_115018973 1.49 ENST00000371936.5
IL13RA2
interleukin 13 receptor subunit alpha 2
chr17_+_42998779 1.47 ENST00000586277.5
RPL27
ribosomal protein L27
chr4_+_143433491 1.40 ENST00000512843.1
GAB1
GRB2 associated binding protein 1
chr18_+_58362467 1.37 ENST00000675101.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr8_-_38176441 1.35 ENST00000311351.9
LSM1
LSM1 homolog, mRNA degradation associated
chr6_-_144095556 1.34 ENST00000367569.4
SF3B5
splicing factor 3b subunit 5
chr17_+_42998264 1.34 ENST00000589037.5
RPL27
ribosomal protein L27
chr4_-_102825767 1.34 ENST00000505207.5
ENST00000502404.5
ENST00000507845.5
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr11_-_62556230 1.31 ENST00000530285.5
AHNAK
AHNAK nucleoprotein
chr13_-_44474296 1.30 ENST00000611198.4
TSC22D1
TSC22 domain family member 1
chr9_-_76906041 1.28 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
PRUNE2
prune homolog 2 with BCH domain
chr15_-_43220989 1.28 ENST00000540029.5
ENST00000441366.7
ENST00000648595.1
EPB42
erythrocyte membrane protein band 4.2
chr12_+_22046183 1.26 ENST00000229329.7
CMAS
cytidine monophosphate N-acetylneuraminic acid synthetase
chr13_+_114235066 1.26 ENST00000252458.6
CDC16
cell division cycle 16
chr16_-_3024230 1.26 ENST00000572355.5
ENST00000574980.5
ENST00000354679.3
ENST00000573842.1
HCFC1R1
host cell factor C1 regulator 1
chr4_+_37960397 1.26 ENST00000504686.2
PTTG2
pituitary tumor-transforming 2
chr3_-_48595267 1.24 ENST00000328333.12
ENST00000681320.1
COL7A1
collagen type VII alpha 1 chain
chr6_-_127459364 1.21 ENST00000487331.2
ENST00000483725.8
KIAA0408
KIAA0408
chr10_+_16436996 1.20 ENST00000535784.7
PTER
phosphotriesterase related
chr16_-_18900044 1.18 ENST00000565224.5
ENST00000330588.4
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr11_-_119030848 1.14 ENST00000330775.9
ENST00000357590.9
ENST00000538950.5
ENST00000545985.5
SLC37A4
solute carrier family 37 member 4
chr4_-_170003738 1.13 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibril associated protein 3 like
chr11_-_72112669 1.10 ENST00000545944.5
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr9_+_114587706 1.09 ENST00000677115.1
ENST00000677452.1
ENST00000374050.4
ENST00000677498.1
ENST00000679150.1
ATP6V1G1
ATPase H+ transporting V1 subunit G1
chrX_-_103502853 1.07 ENST00000372633.1
RAB40A
RAB40A, member RAS oncogene family
chr4_+_17577487 1.07 ENST00000606142.5
LAP3
leucine aminopeptidase 3
chr3_+_155083889 1.04 ENST00000680282.1
MME
membrane metalloendopeptidase
chr11_-_72112750 1.03 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
ANAPC15
anaphase promoting complex subunit 15
chr1_+_84408230 1.02 ENST00000370662.3
DNASE2B
deoxyribonuclease 2 beta
chr14_-_67600132 1.00 ENST00000558493.1
ENST00000561272.5
PIGH
phosphatidylinositol glycan anchor biosynthesis class H
chr6_-_123636979 0.98 ENST00000662930.1
TRDN
triadin
chr14_-_67600258 0.97 ENST00000559581.5
ENST00000216452.9
ENST00000560722.5
ENST00000559415.1
PIGH
phosphatidylinositol glycan anchor biosynthesis class H
chr4_-_74794514 0.94 ENST00000395743.8
BTC
betacellulin
chr6_-_159789572 0.93 ENST00000420894.6
ENST00000539756.1
ENST00000544255.5
ENST00000321394.12
TCP1
t-complex 1
chr12_+_80716906 0.91 ENST00000228644.4
MYF5
myogenic factor 5
chr1_+_173824694 0.91 ENST00000647645.1
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr12_-_56645955 0.89 ENST00000552959.5
ENST00000551020.5
ENST00000553007.2
ENST00000262030.8
ATP5F1B
ATP synthase F1 subunit beta
chrX_+_151912878 0.89 ENST00000276344.6
MAGEA4
MAGE family member A4
chr2_+_223051814 0.86 ENST00000281830.3
KCNE4
potassium voltage-gated channel subfamily E regulatory subunit 4
chr5_-_150758989 0.84 ENST00000447998.7
ENST00000446090.6
ENST00000627368.2
DCTN4
dynactin subunit 4
chr10_-_28282086 0.84 ENST00000375719.7
ENST00000375732.5
MPP7
membrane palmitoylated protein 7
chr17_+_42998379 0.82 ENST00000253788.12
ENST00000589913.6
RPL27
ribosomal protein L27
chr4_-_89836213 0.79 ENST00000618500.4
ENST00000508895.5
SNCA
synuclein alpha
chr3_-_116445458 0.78 ENST00000490035.7
LSAMP
limbic system associated membrane protein
chr3_+_132597260 0.76 ENST00000249887.3
ACKR4
atypical chemokine receptor 4
chr1_-_31065671 0.73 ENST00000440538.6
ENST00000424085.6
ENST00000257075.9
ENST00000373747.7
ENST00000426105.7
ENST00000525843.5
ENST00000373742.6
PUM1
pumilio RNA binding family member 1
chr4_-_89835617 0.68 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
SNCA
synuclein alpha
chr19_+_44891206 0.67 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
TOMM40
translocase of outer mitochondrial membrane 40
chr1_+_186828941 0.63 ENST00000367466.4
PLA2G4A
phospholipase A2 group IVA
chr15_+_84603896 0.61 ENST00000541040.5
ENST00000538076.5
ENST00000485222.2
ZSCAN2
zinc finger and SCAN domain containing 2
chr1_+_173824626 0.59 ENST00000648960.1
ENST00000648807.1
ENST00000649067.1
ENST00000649689.2
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr5_+_75611182 0.58 ENST00000672850.1
ENST00000672844.1
ANKDD1B
ankyrin repeat and death domain containing 1B
chr11_-_101583985 0.57 ENST00000344327.8
TRPC6
transient receptor potential cation channel subfamily C member 6
chr13_-_48095096 0.56 ENST00000258648.7
ENST00000378586.5
MED4
mediator complex subunit 4
chr7_-_139109702 0.54 ENST00000471652.1
ENST00000242351.10
ZC3HAV1
zinc finger CCCH-type containing, antiviral 1
chr12_-_124914056 0.52 ENST00000541272.1
ENST00000535131.1
UBC
ubiquitin C
chr7_+_5898716 0.51 ENST00000325974.9
ENST00000628813.2
CCZ1
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
chr1_-_21783134 0.49 ENST00000308271.14
USP48
ubiquitin specific peptidase 48
chr6_-_57222244 0.47 ENST00000468148.6
RAB23
RAB23, member RAS oncogene family
chr2_+_172821575 0.46 ENST00000397087.7
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr21_-_45544392 0.46 ENST00000443742.1
ENST00000528477.1
ENST00000567670.5
SLC19A1
solute carrier family 19 member 1
chr11_+_9461003 0.44 ENST00000438144.6
ENST00000396602.7
ENST00000526657.5
ENST00000299606.6
ENST00000534265.5
ENST00000412390.6
ZNF143
zinc finger protein 143
chr1_+_196652022 0.40 ENST00000367429.9
ENST00000630130.2
ENST00000359637.2
CFH
complement factor H
chr11_+_64305497 0.38 ENST00000406310.6
ENST00000677967.1
ENST00000000442.11
ESRRA
estrogen related receptor alpha
chr17_+_50532713 0.37 ENST00000503690.5
ENST00000514874.5
ENST00000268933.8
EPN3
epsin 3
chr4_+_87608529 0.35 ENST00000651931.1
DSPP
dentin sialophosphoprotein
chr8_-_85378105 0.33 ENST00000521846.5
ENST00000523022.6
ENST00000524324.5
ENST00000519991.5
ENST00000520663.5
ENST00000517590.5
ENST00000522579.5
ENST00000522814.5
ENST00000522662.5
ENST00000523858.5
ENST00000519129.5
CA1
carbonic anhydrase 1
chr19_+_54105923 0.32 ENST00000420296.1
NDUFA3
NADH:ubiquinone oxidoreductase subunit A3
chr6_+_43298326 0.31 ENST00000372574.7
SLC22A7
solute carrier family 22 member 7
chr16_+_83953232 0.30 ENST00000565123.5
ENST00000393306.6
OSGIN1
oxidative stress induced growth inhibitor 1
chr14_+_22766522 0.28 ENST00000285848.9
ENST00000612549.6
ENST00000431881.6
ENST00000412791.5
ENST00000358043.5
OXA1L
OXA1L mitochondrial inner membrane protein
chr9_+_129803175 0.26 ENST00000259339.7
ENST00000427860.1
TOR1B
torsin family 1 member B
chrX_-_31266925 0.25 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
DMD
dystrophin
chr6_+_26124161 0.24 ENST00000377791.4
ENST00000602637.1
H2AC6
H2A clustered histone 6
chr1_+_202462730 0.18 ENST00000290419.9
ENST00000491336.5
PPP1R12B
protein phosphatase 1 regulatory subunit 12B
chr1_+_54715837 0.18 ENST00000371281.4
TTC4
tetratricopeptide repeat domain 4
chr12_+_53441724 0.17 ENST00000551003.5
ENST00000429243.7
ENST00000549068.5
ENST00000549740.5
ENST00000546581.5
ENST00000549581.5
ENST00000547368.5
ENST00000379786.8
ENST00000551945.5
ENST00000547717.1
PRR13
ENSG00000257379.1
proline rich 13
novel transcript
chr11_-_118565992 0.13 ENST00000264020.6
IFT46
intraflagellar transport 46
chr7_+_121873089 0.12 ENST00000651065.1
PTPRZ1
protein tyrosine phosphatase receptor type Z1
chr1_-_208244375 0.12 ENST00000367033.4
PLXNA2
plexin A2
chr15_-_33067884 0.12 ENST00000334528.13
FMN1
formin 1
chr16_-_31065011 0.11 ENST00000539836.3
ENST00000535577.5
ENST00000442862.2
ZNF668
zinc finger protein 668
chr1_-_216423396 0.07 ENST00000366942.3
ENST00000674083.1
ENST00000307340.8
USH2A
usherin
chr6_+_53065385 0.07 ENST00000323557.12
FBXO9
F-box protein 9
chr15_-_28322179 0.06 ENST00000261609.13
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr9_-_21228222 0.05 ENST00000413767.2
IFNA17
interferon alpha 17
chr20_+_142573 0.04 ENST00000382398.4
DEFB126
defensin beta 126
chr13_+_27424583 0.03 ENST00000381140.10
GTF3A
general transcription factor IIIA
chr13_+_101489940 0.02 ENST00000376162.7
ITGBL1
integrin subunit beta like 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 11.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
2.2 8.6 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
1.8 10.9 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.7 5.2 GO:0097069 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
1.4 4.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
1.4 8.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
1.3 7.7 GO:0019255 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
1.2 7.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.2 5.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.2 8.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
1.1 4.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.0 2.0 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.9 2.8 GO:0002368 B cell cytokine production(GO:0002368)
0.9 13.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.8 5.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.6 3.8 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.6 1.9 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.6 6.1 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5 1.6 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.5 1.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.5 2.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.5 5.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.5 1.5 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.5 2.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.5 1.9 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.4 2.6 GO:0035617 stress granule disassembly(GO:0035617)
0.4 9.9 GO:0051639 actin filament network formation(GO:0051639)
0.4 1.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 2.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.4 3.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.4 5.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.4 2.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.4 4.8 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.4 2.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.3 3.0 GO:0060613 fat pad development(GO:0060613)
0.3 5.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.3 1.0 GO:1903781 endoplasmic reticulum membrane organization(GO:0090158) positive regulation of cardiac conduction(GO:1903781)
0.3 2.1 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.3 4.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 4.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 1.7 GO:0071475 cellular hyperosmotic salinity response(GO:0071475) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.2 1.5 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.2 6.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 2.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.2 4.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 2.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 10.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.2 17.5 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 8.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 3.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 2.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 6.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.2 3.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 1.5 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.2 1.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.6 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 9.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 2.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 2.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.6 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 2.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 8.5 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.1 1.0 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.9 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 8.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 4.3 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.3 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.7 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.5 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 3.1 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 2.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 2.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 1.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 1.6 GO:0010842 retina layer formation(GO:0010842)
0.1 1.1 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 1.9 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097)
0.0 2.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.9 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 2.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 1.0 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.8 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0072093 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 2.0 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 2.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 1.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785) limb bud formation(GO:0060174)
0.0 14.2 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 3.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 3.5 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.4 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
1.7 5.1 GO:0031262 Ndc80 complex(GO:0031262)
1.7 5.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.2 3.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.9 7.3 GO:0000796 condensin complex(GO:0000796)
0.7 20.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.7 3.5 GO:0070847 core mediator complex(GO:0070847)
0.7 4.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.6 2.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.5 7.1 GO:0005915 zonula adherens(GO:0005915)
0.5 3.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.4 2.9 GO:0005683 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.4 2.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.4 5.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.4 10.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 1.7 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.3 2.8 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696)
0.3 6.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 5.9 GO:0036020 endolysosome membrane(GO:0036020)
0.2 6.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 4.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 1.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 2.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 4.1 GO:0000242 pericentriolar material(GO:0000242)
0.2 1.0 GO:0030314 junctional membrane complex(GO:0030314)
0.2 2.6 GO:0035253 ciliary rootlet(GO:0035253)
0.2 2.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 2.4 GO:0017119 Golgi transport complex(GO:0017119)
0.2 2.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 2.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 2.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 2.9 GO:0005685 U1 snRNP(GO:0005685)
0.1 12.0 GO:0035580 specific granule lumen(GO:0035580)
0.1 1.3 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.9 GO:0071438 invadopodium membrane(GO:0071438)
0.1 3.8 GO:0005921 gap junction(GO:0005921)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 9.8 GO:0032432 actin filament bundle(GO:0032432)
0.1 4.8 GO:0099738 cell cortex region(GO:0099738)
0.1 1.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.5 GO:0016235 aggresome(GO:0016235)
0.1 1.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 10.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 3.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 2.1 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 2.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.8 GO:0043034 costamere(GO:0043034)
0.0 2.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 2.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 4.1 GO:0005938 cell cortex(GO:0005938)
0.0 10.4 GO:0005925 focal adhesion(GO:0005925)
0.0 4.4 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 4.9 GO:0005874 microtubule(GO:0005874)
0.0 1.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 40.3 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
1.7 5.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
1.0 4.1 GO:0070404 NADH binding(GO:0070404)
1.0 10.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.0 8.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.8 6.3 GO:0004111 creatine kinase activity(GO:0004111)
0.8 2.3 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.7 2.6 GO:0099609 microtubule lateral binding(GO:0099609)
0.6 1.9 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.6 2.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.6 2.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.5 1.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.5 2.8 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.4 3.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 5.0 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.4 8.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 4.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 1.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.3 2.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.3 4.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 1.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3 2.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 5.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 2.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 5.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 3.8 GO:0005522 profilin binding(GO:0005522)
0.2 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 5.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 5.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 6.9 GO:0008009 chemokine activity(GO:0008009)
0.1 3.2 GO:0000339 RNA cap binding(GO:0000339)
0.1 3.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.1 GO:0030297 ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.7 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 1.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 4.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.9 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 10.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.9 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 2.2 GO:0031489 myosin V binding(GO:0031489)
0.1 1.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.7 GO:0015288 porin activity(GO:0015288)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.5 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 2.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 7.9 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 1.5 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 6.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 2.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 3.5 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.1 7.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 10.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 4.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 5.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 4.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 16.6 GO:0045296 cadherin binding(GO:0045296)
0.0 2.7 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 5.4 GO:0051015 actin filament binding(GO:0051015)
0.0 10.7 GO:0005525 GTP binding(GO:0005525)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.8 GO:0019956 chemokine binding(GO:0019956)
0.0 1.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 6.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.3 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 6.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 16.3 GO:0042802 identical protein binding(GO:0042802)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.4 PID AURORA B PATHWAY Aurora B signaling
0.2 4.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 7.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 13.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 8.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 6.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 3.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 2.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 5.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 5.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.0 PID ATR PATHWAY ATR signaling pathway
0.0 3.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 8.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 4.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.5 5.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 7.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 4.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 4.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 4.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.2 5.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 8.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 15.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 8.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 2.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 3.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 6.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 4.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 7.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 4.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 5.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 6.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.7 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 11.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.7 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 3.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 3.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.0 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.8 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 0.6 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 3.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 3.6 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis