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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR0B1

Z-value: 0.84

Motif logo

Transcription factors associated with NR0B1

Gene Symbol Gene ID Gene Info
ENSG00000169297.8 NR0B1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR0B1hg38_v1_chrX_-_30309387_30309392-0.036.5e-01Click!

Activity profile of NR0B1 motif

Sorted Z-values of NR0B1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR0B1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_29633171 7.18 ENST00000377034.9
gamma-aminobutyric acid type B receptor subunit 1
chr6_-_29633056 6.51 ENST00000377016.8
gamma-aminobutyric acid type B receptor subunit 1
chr10_+_110226805 5.31 ENST00000651495.1
ENST00000652506.1
ENST00000651811.1
ENST00000651167.1
ENST00000651516.1
ENST00000651467.1
ENST00000651004.1
ENST00000650843.1
ENST00000650644.1
ENST00000650696.1
ENST00000652604.1
ENST00000652463.1
ENST00000650810.1
ENST00000650952.1
ENST00000652028.1
ENST00000651866.1
ENST00000651848.1
ENST00000442296.5
ENST00000369612.1
MAX interactor 1, dimerization protein
chr2_+_30231524 4.97 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr17_-_3696198 4.53 ENST00000345901.7
purinergic receptor P2X 5
chr17_-_3696133 4.46 ENST00000225328.10
purinergic receptor P2X 5
chr22_+_22895368 4.36 ENST00000390321.2
immunoglobulin lambda constant 1
chr2_-_225042433 4.36 ENST00000258390.12
dedicator of cytokinesis 10
chr11_-_64745331 4.13 ENST00000377489.5
ENST00000354024.7
RAS guanyl releasing protein 2
chrX_-_153926254 3.74 ENST00000393721.5
ENST00000370028.7
ENST00000350060.10
Rho GTPase activating protein 4
chr5_+_112976757 3.62 ENST00000389063.3
decapping mRNA 2
chr17_-_3696033 3.54 ENST00000551178.5
ENST00000552276.5
ENST00000547178.5
purinergic receptor P2X 5
chr20_+_58891981 3.43 ENST00000488652.6
ENST00000476935.6
ENST00000492907.6
ENST00000603546.2
GNAS complex locus
chr17_+_78169127 3.26 ENST00000590201.1
synaptogyrin 2
chr11_+_65096115 3.22 ENST00000530773.5
ENST00000279281.8
ENST00000529180.1
ENST00000639871.1
VPS51 subunit of GARP complex
chr5_+_68215738 3.12 ENST00000521381.6
ENST00000521657.5
phosphoinositide-3-kinase regulatory subunit 1
chr12_+_56080155 3.05 ENST00000267101.8
erb-b2 receptor tyrosine kinase 3
chr10_+_28532744 3.04 ENST00000651598.1
ENST00000526722.1
ENST00000375646.5
WW domain containing adaptor with coiled-coil
chr12_+_56079843 2.93 ENST00000549282.5
ENST00000549061.5
ENST00000683059.1
erb-b2 receptor tyrosine kinase 3
chr8_+_38787218 2.81 ENST00000317827.9
ENST00000276520.12
transforming acidic coiled-coil containing protein 1
chr20_+_47501929 2.72 ENST00000371997.3
nuclear receptor coactivator 3
chr2_+_231708511 2.70 ENST00000341369.11
ENST00000409115.8
ENST00000409683.5
prothymosin alpha
chr16_-_69385968 2.68 ENST00000567296.6
ENST00000254942.8
telomeric repeat binding factor 2
chr15_+_90903288 2.61 ENST00000559717.6
mannosidase alpha class 2A member 2
chr20_+_47501875 2.55 ENST00000371998.8
ENST00000372004.7
nuclear receptor coactivator 3
chr12_-_57846686 2.47 ENST00000548823.1
ENST00000398073.7
CTD small phosphatase 2
chr11_-_64744811 2.44 ENST00000377497.7
ENST00000377487.5
ENST00000430645.1
RAS guanyl releasing protein 2
chr20_+_58891738 2.42 ENST00000682803.1
GNAS complex locus
chr17_+_7884783 2.42 ENST00000380358.9
chromodomain helicase DNA binding protein 3
chr1_+_2556361 2.42 ENST00000355716.5
TNF receptor superfamily member 14
chr1_-_40665654 2.40 ENST00000372684.8
regulating synaptic membrane exocytosis 3
chr4_-_89836963 2.40 ENST00000420646.6
ENST00000673718.1
synuclein alpha
chr1_-_154627576 2.38 ENST00000648311.1
adenosine deaminase RNA specific
chr20_+_58891691 2.38 ENST00000468895.6
GNAS complex locus
chr1_+_5992639 2.37 ENST00000666163.1
ENST00000671676.1
ENST00000658883.1
ENST00000445501.6
ENST00000668706.1
ENST00000653262.1
ENST00000389632.9
ENST00000341524.6
ENST00000462676.3
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr1_+_220690354 2.31 ENST00000294889.6
chromosome 1 open reading frame 115
chr5_+_139273752 2.27 ENST00000509990.5
ENST00000506147.5
ENST00000512107.5
matrin 3
chr16_-_11586903 2.27 ENST00000571459.5
ENST00000570798.5
ENST00000622633.5
ENST00000572255.5
ENST00000574763.5
ENST00000574703.5
ENST00000571277.1
lipopolysaccharide induced TNF factor
chr1_-_154627945 2.26 ENST00000681683.1
ENST00000368471.8
ENST00000649042.1
ENST00000680270.1
ENST00000649022.2
ENST00000681056.1
ENST00000649724.1
adenosine deaminase RNA specific
chr20_+_58891704 2.25 ENST00000371081.5
ENST00000338783.7
GNAS complex locus
chr1_+_153728042 2.14 ENST00000318967.7
ENST00000435409.6
integrator complex subunit 3
chr2_-_43995999 2.13 ENST00000683213.1
ENST00000409946.6
leucine rich pentatricopeptide repeat containing
chr5_-_138033021 2.12 ENST00000033079.7
family with sequence similarity 13 member B
chr12_+_78863962 2.10 ENST00000393240.7
synaptotagmin 1
chr2_-_43995950 2.08 ENST00000683590.1
ENST00000683623.1
ENST00000682779.1
ENST00000682546.1
ENST00000683220.1
ENST00000683125.1
ENST00000683833.1
ENST00000683989.1
ENST00000682480.1
ENST00000260665.12
ENST00000682308.1
ENST00000682885.1
ENST00000409659.6
ENST00000447246.2
leucine rich pentatricopeptide repeat containing
chrX_-_136767322 2.03 ENST00000370620.5
Rac/Cdc42 guanine nucleotide exchange factor 6
chr2_+_54115396 2.01 ENST00000406041.5
acylphosphatase 2
chr4_-_82430399 1.98 ENST00000630827.1
ENST00000295470.10
heterogeneous nuclear ribonucleoprotein D like
chr5_+_139274093 1.92 ENST00000448190.6
ENST00000648842.1
ENST00000507692.5
ENST00000506188.5
ENST00000513259.5
ENST00000507197.5
ENST00000508735.5
ENST00000514110.5
ENST00000505522.6
ENST00000361059.7
ENST00000514694.5
ENST00000504203.5
ENST00000502929.5
ENST00000394800.6
ENST00000509644.5
ENST00000505016.2
small nucleolar RNA host gene 4
matrin 3
chr4_-_108168950 1.91 ENST00000379951.6
lymphoid enhancer binding factor 1
chr8_+_94641074 1.89 ENST00000423620.6
epithelial splicing regulatory protein 1
chr4_+_82430638 1.89 ENST00000509635.5
ENST00000505846.5
enolase-phosphatase 1
chr5_+_10353668 1.86 ENST00000274140.10
ENST00000449913.6
ENST00000503788.5
membrane associated ring-CH-type finger 6
chr4_+_82430563 1.85 ENST00000273920.8
enolase-phosphatase 1
chr3_+_23917170 1.79 ENST00000643707.1
ribosomal protein L15
chr5_+_43120883 1.79 ENST00000515326.5
ENST00000682664.1
zinc finger protein 131
chr4_-_108168919 1.79 ENST00000265165.6
lymphoid enhancer binding factor 1
chr19_-_47471886 1.78 ENST00000236877.11
ENST00000597014.1
solute carrier family 8 member A2
chr10_+_28533108 1.78 ENST00000354911.9
WW domain containing adaptor with coiled-coil
chr11_+_35662739 1.78 ENST00000299413.7
tripartite motif containing 44
chr1_-_29181809 1.75 ENST00000466448.4
ENST00000373795.7
serine and arginine rich splicing factor 4
chr17_-_55421818 1.73 ENST00000262065.8
ENST00000649377.1
monocyte to macrophage differentiation associated
chr2_+_54115437 1.73 ENST00000303536.8
ENST00000394666.7
acylphosphatase 2
chr12_-_27780236 1.72 ENST00000381273.4
MANSC domain containing 4
chr4_+_155758990 1.70 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
guanylate cyclase 1 soluble subunit beta 1
chr16_+_58463663 1.67 ENST00000258187.9
NDRG family member 4
chr4_-_36244438 1.63 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_22822779 1.60 ENST00000372879.8
translocase of outer mitochondrial membrane 7
chrX_+_55452119 1.56 ENST00000342972.3
MAGE family member H1
chr6_+_57090010 1.53 ENST00000510483.5
ENST00000357489.7
zinc finger protein 451
chr21_-_31558977 1.51 ENST00000286827.7
ENST00000541036.5
TIAM Rac1 associated GEF 1
chr8_-_73746830 1.51 ENST00000524300.6
ENST00000523558.5
ENST00000521210.5
ENST00000355780.9
ENST00000524104.5
ENST00000521736.5
ENST00000521447.5
ENST00000517542.5
ENST00000521451.5
ENST00000521419.5
ENST00000518502.5
staufen double-stranded RNA binding protein 2
chr18_-_35344408 1.50 ENST00000261332.11
ENST00000399061.3
zinc finger protein 24
chr2_-_175005357 1.48 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr20_+_44885679 1.42 ENST00000353703.9
ENST00000372839.7
ENST00000428262.1
ENST00000445830.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
chr19_-_47471847 1.42 ENST00000594353.1
ENST00000542837.2
solute carrier family 8 member A2
chr7_-_22822829 1.41 ENST00000358435.9
ENST00000621567.1
translocase of outer mitochondrial membrane 7
chr16_+_19168207 1.38 ENST00000355377.7
ENST00000568115.5
synaptotagmin 17
chr2_+_218399838 1.37 ENST00000273062.7
CTD small phosphatase 1
chr5_-_42811884 1.36 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr1_-_32336224 1.32 ENST00000329421.8
MARCKS like 1
chr1_+_226062704 1.30 ENST00000366814.3
ENST00000366815.10
ENST00000655399.1
ENST00000667897.1
H3.3 histone A
chr11_-_76381053 1.26 ENST00000260045.8
THAP domain containing 12
chr16_+_15434577 1.26 ENST00000300006.9
bMERB domain containing 1
chr17_-_44123590 1.26 ENST00000336057.9
histone deacetylase 5
chr16_+_15434475 1.25 ENST00000566490.5
bMERB domain containing 1
chr8_+_26291758 1.24 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr17_-_67245165 1.24 ENST00000580168.5
ENST00000358691.10
helicase with zinc finger
chr7_-_108456378 1.23 ENST00000613830.4
ENST00000413765.6
ENST00000379028.8
neuronal cell adhesion molecule
chr1_-_223364059 1.23 ENST00000343846.7
ENST00000484758.6
ENST00000344029.6
ENST00000366878.9
ENST00000494793.6
ENST00000681285.1
ENST00000680429.1
ENST00000681669.1
ENST00000681305.1
sushi domain containing 4
chr1_+_32886456 1.23 ENST00000373467.4
hippocalcin
chr5_+_134525649 1.21 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr19_-_38229654 1.18 ENST00000412732.5
ENST00000456296.5
double PHD fingers 1
chr1_-_20787287 1.18 ENST00000438032.6
ENST00000424732.5
ENST00000437575.5
heterochromatin protein 1 binding protein 3
chr10_+_87863595 1.18 ENST00000371953.8
phosphatase and tensin homolog
chr1_-_20786610 1.14 ENST00000375000.5
ENST00000312239.10
ENST00000419490.5
ENST00000414993.1
ENST00000443615.1
heterochromatin protein 1 binding protein 3
chr7_-_108456321 1.10 ENST00000379024.8
ENST00000351718.8
neuronal cell adhesion molecule
chr1_-_183635659 1.10 ENST00000367534.5
ENST00000294742.6
actin related protein 2/3 complex subunit 5
chr12_+_56080126 1.09 ENST00000411731.6
erb-b2 receptor tyrosine kinase 3
chr8_-_101205561 1.09 ENST00000519744.5
ENST00000311212.9
ENST00000521272.5
ENST00000519882.5
zinc finger protein 706
chr2_+_112645930 1.09 ENST00000272542.8
solute carrier family 20 member 1
chr15_+_78872809 1.09 ENST00000331268.9
mortality factor 4 like 1
chr6_-_31897200 1.06 ENST00000395728.7
ENST00000375528.8
euchromatic histone lysine methyltransferase 2
chr21_-_32727889 1.05 ENST00000630077.3
ENST00000674204.1
synaptojanin 1
chr19_+_1205761 1.05 ENST00000326873.12
ENST00000586243.5
serine/threonine kinase 11
chr2_+_219627565 1.05 ENST00000273063.10
solute carrier family 4 member 3
chr17_-_42609356 1.05 ENST00000309428.10
reticulophagy regulator family member 3
chr8_-_100952002 1.04 ENST00000521309.5
ENST00000395958.6
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr19_-_2051224 1.02 ENST00000309340.11
ENST00000589534.2
ENST00000250896.9
ENST00000589509.5
MAPK interacting serine/threonine kinase 2
chr2_+_219627650 1.02 ENST00000317151.7
solute carrier family 4 member 3
chr14_+_71320421 1.01 ENST00000381232.8
signal induced proliferation associated 1 like 1
chr2_-_61471062 1.01 ENST00000398571.7
ubiquitin specific peptidase 34
chr17_-_44123628 1.01 ENST00000587135.1
ENST00000225983.10
ENST00000682912.1
ENST00000588703.5
histone deacetylase 5
chr1_-_54406385 1.00 ENST00000610401.5
single stranded DNA binding protein 3
chr8_-_101205455 1.00 ENST00000520984.5
zinc finger protein 706
chr2_-_47906437 1.00 ENST00000403359.8
F-box protein 11
chr2_+_219627622 0.95 ENST00000358055.8
solute carrier family 4 member 3
chr1_-_183635776 0.95 ENST00000359856.11
actin related protein 2/3 complex subunit 5
chr17_+_44308573 0.95 ENST00000590941.5
ENST00000225441.11
ENST00000426726.8
RUN domain containing 3A
chr13_-_30465923 0.94 ENST00000341423.10
ENST00000326004.4
high mobility group box 1
chr21_-_32727933 0.94 ENST00000357345.7
ENST00000429236.5
synaptojanin 1
chr1_+_38991239 0.93 ENST00000432648.8
ENST00000446189.6
ENST00000372984.8
akirin 1
chr7_+_143263412 0.93 ENST00000409500.7
ENST00000443571.6
ENST00000358406.10
ENST00000479303.1
glutathione S-transferase kappa 1
chr14_-_21437235 0.90 ENST00000430710.8
ENST00000646340.1
ENST00000646063.1
chromodomain helicase DNA binding protein 8
chr2_+_219627394 0.90 ENST00000373760.6
solute carrier family 4 member 3
chr21_-_32727985 0.89 ENST00000674351.1
ENST00000674308.1
synaptojanin 1
chr11_+_76381303 0.89 ENST00000662483.1
ENST00000663165.1
ENST00000529331.2
ENST00000321844.6
ENST00000667240.1
GVQW motif containing 3
chr19_-_38229714 0.88 ENST00000416611.5
double PHD fingers 1
chr14_-_106658251 0.87 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr14_+_73490926 0.86 ENST00000304061.8
ribosomal oxygenase 1
chr14_-_21437265 0.86 ENST00000553622.5
ENST00000642518.1
ENST00000557364.6
ENST00000643469.1
chromodomain helicase DNA binding protein 8
chrX_+_19343893 0.85 ENST00000540249.5
ENST00000545074.5
ENST00000379806.9
ENST00000423505.5
ENST00000422285.7
ENST00000417819.5
ENST00000355808.9
ENST00000379805.3
pyruvate dehydrogenase E1 subunit alpha 1
chr12_-_6606320 0.84 ENST00000642594.1
ENST00000644289.1
ENST00000645095.1
chromodomain helicase DNA binding protein 4
chr6_+_391743 0.84 ENST00000380956.9
interferon regulatory factor 4
chr1_-_92961440 0.84 ENST00000370310.5
ENST00000615519.4
ENST00000613902.4
ENST00000616709.4
divergent protein kinase domain 1A
chr14_+_92513766 0.84 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
Ras and Rab interactor 3
chr18_-_5396265 0.83 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr1_-_223363337 0.83 ENST00000608996.5
sushi domain containing 4
chr17_+_4833331 0.82 ENST00000355280.11
ENST00000347992.11
misshapen like kinase 1
chr4_-_151015713 0.81 ENST00000357115.9
LPS responsive beige-like anchor protein
chr14_+_73058521 0.80 ENST00000527432.5
ENST00000531500.5
ENST00000261973.12
ENST00000525321.5
ENST00000526754.5
RNA binding motif protein 25
chr19_+_49119531 0.79 ENST00000334186.9
PTPRF interacting protein alpha 3
chr6_+_43182165 0.78 ENST00000372647.6
ENST00000252050.9
cullin 9
chr17_-_7252054 0.78 ENST00000575783.5
ENST00000573600.5
CTD nuclear envelope phosphatase 1
chr10_+_68956158 0.77 ENST00000354185.9
DExD-box helicase 21
chr13_-_98577094 0.76 ENST00000539966.6
serine/threonine kinase 24
chr3_-_125375249 0.76 ENST00000484491.5
ENST00000492394.5
ENST00000471196.1
ENST00000468369.5
ENST00000485866.5
ENST00000360647.9
zinc finger protein 148
chr3_-_47475811 0.76 ENST00000265565.10
ENST00000428413.5
SREBF chaperone
chr16_-_229398 0.76 ENST00000430864.5
ENST00000293872.13
ENST00000629543.2
ENST00000337351.8
ENST00000397783.5
LUC7 like
chr6_-_34392627 0.75 ENST00000607016.2
nudix hydrolase 3
chr16_-_1964803 0.75 ENST00000526522.5
ENST00000527302.1
ENST00000529806.5
ENST00000343262.9
ENST00000563194.1
ribosomal protein S2
chr4_-_151015263 0.74 ENST00000510413.5
ENST00000507224.5
ENST00000651943.2
LPS responsive beige-like anchor protein
chr22_+_29480211 0.73 ENST00000310624.7
neurofilament heavy
chr15_+_57592003 0.73 ENST00000587652.5
ENST00000649429.1
ENST00000380568.7
ENST00000380565.8
GRINL1A complex locus 1
myocardial zonula adherens protein
chr22_-_49824804 0.71 ENST00000216267.12
ENST00000457780.3
bromodomain containing 1
chr12_+_12611839 0.70 ENST00000228865.3
cAMP responsive element binding protein like 2
chr20_-_3173516 0.70 ENST00000360342.7
ENST00000645462.1
ENST00000337576.7
leucine zipper tumor suppressor family member 3
chr11_-_119101814 0.68 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr17_+_62479025 0.67 ENST00000326270.13
ENST00000682203.1
ENST00000343388.11
ENST00000683536.1
ENST00000684440.1
ENST00000684772.1
ENST00000682075.1
ENST00000683104.1
ENST00000684012.1
tousled like kinase 2
chr15_+_78873030 0.67 ENST00000558502.5
mortality factor 4 like 1
chr5_-_135399211 0.65 ENST00000312469.8
ENST00000423969.6
macroH2A.1 histone
chr16_-_48610150 0.65 ENST00000262384.4
NEDD4 binding protein 1
chr19_-_18606779 0.64 ENST00000684169.1
ENST00000392386.8
cytokine receptor like factor 1
chr15_+_40844018 0.63 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chrX_-_69165509 0.61 ENST00000361478.1
praja ring finger ubiquitin ligase 1
chr1_-_66801276 0.59 ENST00000304526.3
insulin like 5
chr17_+_80101562 0.58 ENST00000302262.8
ENST00000577106.5
ENST00000390015.7
alpha glucosidase
chrX_-_69165430 0.57 ENST00000374584.3
ENST00000590146.1
ENST00000374571.5
praja ring finger ubiquitin ligase 1
chr1_-_19484635 0.57 ENST00000433834.5
capping actin protein of muscle Z-line subunit beta
chr1_+_11691688 0.55 ENST00000294485.6
dorsal inhibitory axon guidance protein
chr20_+_37179310 0.55 ENST00000373632.8
ENST00000237530.11
ribophorin II
chr2_+_172735838 0.53 ENST00000397081.8
Rap guanine nucleotide exchange factor 4
chr20_-_5113067 0.53 ENST00000342308.10
ENST00000612323.4
ENST00000202834.11
transmembrane protein 230
chr13_+_19958708 0.52 ENST00000382874.6
ENST00000610343.5
zinc finger MYM-type containing 2
chr17_-_7251955 0.51 ENST00000318988.10
CTD nuclear envelope phosphatase 1
chr8_+_127736046 0.51 ENST00000641036.1
ENST00000377970.6
MYC proto-oncogene, bHLH transcription factor
chr6_-_111483700 0.51 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr5_+_175796712 0.50 ENST00000515502.1
complexin 2
chr13_+_19958760 0.50 ENST00000382871.3
zinc finger MYM-type containing 2
chr2_-_43595963 0.50 ENST00000405006.8
THADA armadillo repeat containing
chr12_+_7189675 0.50 ENST00000675855.1
ENST00000434354.6
ENST00000544456.5
ENST00000545574.5
ENST00000420616.6
peroxisomal biogenesis factor 5
chrX_+_49171918 0.49 ENST00000376322.7
proteolipid protein 2
chr11_-_65857763 0.48 ENST00000531407.5
cofilin 1
chr17_-_7252482 0.48 ENST00000572043.5
CTD nuclear envelope phosphatase 1
chr15_-_50765656 0.47 ENST00000261854.10
signal peptide peptidase like 2A
chr2_+_70900546 0.47 ENST00000234392.3
ventral anterior homeobox 2
chr16_-_68236069 0.46 ENST00000473183.7
ENST00000565858.5
epithelial splicing regulatory protein 2
chr2_-_43595980 0.46 ENST00000403856.1
ENST00000404790.5
ENST00000405975.7
THADA armadillo repeat containing
chr4_-_86357722 0.46 ENST00000641341.1
ENST00000642038.1
ENST00000641116.1
ENST00000641767.1
ENST00000639242.1
ENST00000638313.1
mitogen-activated protein kinase 10
chr1_-_235866916 0.46 ENST00000389794.7
lysosomal trafficking regulator
chr9_+_93576557 0.46 ENST00000359246.9
ENST00000375376.8
PHD finger protein 2
chr16_+_2964216 0.46 ENST00000572045.5
ENST00000571007.5
ENST00000575885.5
ENST00000303746.10
ENST00000319500.10
kringle containing transmembrane protein 2
chr17_-_52158678 0.45 ENST00000451037.7
carbonic anhydrase 10
chr8_-_101205240 0.45 ENST00000520347.5
ENST00000523922.1
zinc finger protein 706
chr3_-_100401028 0.43 ENST00000284320.6
translocase of outer mitochondrial membrane 70
chr12_-_53321544 0.42 ENST00000394384.7
ENST00000209873.9
aladin WD repeat nucleoporin
chr1_+_222644247 0.42 ENST00000340535.11
MIA SH3 domain ER export factor 3
chr17_-_16215520 0.42 ENST00000582357.5
ENST00000436828.5
ENST00000268712.8
ENST00000411510.5
ENST00000395857.7
nuclear receptor corepressor 1
chr5_+_176365455 0.41 ENST00000310389.6
ADP ribosylation factor like GTPase 10
chr17_+_66964638 0.41 ENST00000262138.4
calcium voltage-gated channel auxiliary subunit gamma 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
1.0 5.0 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
1.0 4.8 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.9 2.7 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.9 5.3 GO:0035624 receptor transactivation(GO:0035624)
0.8 0.8 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.8 4.6 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.7 3.7 GO:0071895 odontoblast differentiation(GO:0071895)
0.7 2.9 GO:1904980 positive regulation of endosome organization(GO:1904980)
0.7 2.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.7 10.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.6 3.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.5 1.5 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.5 2.4 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.4 3.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.4 2.4 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.4 11.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.4 4.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.4 1.5 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3 3.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.3 1.0 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.3 3.7 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.3 14.9 GO:0031280 negative regulation of cyclase activity(GO:0031280)
0.3 2.4 GO:0070995 NADPH oxidation(GO:0070995)
0.3 1.2 GO:1903984 rhythmic synaptic transmission(GO:0060024) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 2.0 GO:0006013 mannose metabolic process(GO:0006013)
0.2 0.9 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.2 4.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 2.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 7.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 0.9 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.2 3.1 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.2 0.6 GO:0002086 diaphragm contraction(GO:0002086)
0.2 0.2 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325)
0.2 2.1 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.2 0.7 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.2 1.8 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.2 1.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 5.3 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.2 1.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 0.8 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 2.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 1.0 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.7 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 2.3 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 0.5 GO:0090095 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.8 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.5 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 1.9 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.1 2.3 GO:0070828 heterochromatin organization(GO:0070828)
0.1 0.8 GO:0072553 terminal button organization(GO:0072553)
0.1 0.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 1.7 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 1.9 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.4 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.5 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 1.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 2.1 GO:0016180 snRNA processing(GO:0016180)
0.1 0.3 GO:1902908 regulation of melanosome transport(GO:1902908)
0.1 0.9 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 3.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 1.0 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.9 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.1 1.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 7.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.3 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.4 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 1.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 3.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.1 0.3 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.1 4.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 1.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 1.8 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 1.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.5 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.9 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 1.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 3.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 2.6 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 2.0 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 2.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 2.2 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 1.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.7 GO:0035902 response to immobilization stress(GO:0035902)
0.0 1.0 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.7 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.8 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.9 GO:0019933 cAMP-mediated signaling(GO:0019933) cyclic-nucleotide-mediated signaling(GO:0019935)
0.0 0.8 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.3 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.8 3.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.7 4.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.6 12.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.5 2.1 GO:0070876 SOSS complex(GO:0070876)
0.5 2.4 GO:1990031 pinceau fiber(GO:1990031)
0.5 1.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.5 3.2 GO:1990745 EARP complex(GO:1990745)
0.4 3.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.4 2.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 2.7 GO:0070187 telosome(GO:0070187)
0.3 2.3 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 3.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 1.1 GO:0036398 TCR signalosome(GO:0036398)
0.2 3.2 GO:0000786 nucleosome(GO:0000786)
0.2 3.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 10.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.2 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 3.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 2.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 2.9 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 4.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.5 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 4.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.8 GO:0043194 axon initial segment(GO:0043194)
0.1 0.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 2.1 GO:0071565 nBAF complex(GO:0071565)
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 2.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203)
0.0 1.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 7.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 2.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 3.9 GO:0016605 PML body(GO:0016605)
0.0 5.3 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 4.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.8 GO:0031672 A band(GO:0031672)
0.0 3.2 GO:0030426 growth cone(GO:0030426)
0.0 4.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 2.7 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 3.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.5 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.7 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 5.3 GO:0043235 receptor complex(GO:0043235)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.2 3.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
1.1 12.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.6 3.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.6 3.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.6 7.1 GO:0038132 neuregulin binding(GO:0038132)
0.6 4.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.5 2.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.4 10.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 2.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.4 2.9 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.4 3.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.4 2.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.4 1.2 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.3 6.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 3.7 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 2.6 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.3 1.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 3.0 GO:0015266 protein channel activity(GO:0015266)
0.2 3.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 2.7 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 0.9 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 1.4 GO:0050815 phosphoserine binding(GO:0050815)
0.2 3.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 0.8 GO:0052844 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.6 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 4.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.9 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.9 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 1.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 4.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.6 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 1.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.4 GO:0008430 selenium binding(GO:0008430)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.8 GO:0050733 RS domain binding(GO:0050733)
0.1 0.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 4.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.2 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.9 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 1.3 GO:0048156 tau protein binding(GO:0048156)
0.1 2.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 3.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 2.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 2.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 3.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0035240 dopamine binding(GO:0035240)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.1 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 1.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 5.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 3.2 GO:0051015 actin filament binding(GO:0051015)
0.0 2.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 3.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.8 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 1.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.5 GO:0019956 chemokine binding(GO:0019956)
0.0 1.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 1.2 GO:0004386 helicase activity(GO:0004386)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 5.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.1 PID IL5 PATHWAY IL5-mediated signaling events
0.1 5.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.4 PID ATM PATHWAY ATM pathway
0.1 5.4 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 4.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.8 PID AURORA A PATHWAY Aurora A signaling
0.1 6.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 5.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 13.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 2.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.3 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 10.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.3 5.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 8.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 7.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 3.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 3.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 3.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 7.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 5.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 2.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 4.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 4.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 3.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling