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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR1H2

Z-value: 0.75

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Transcription factors associated with NR1H2

Gene Symbol Gene ID Gene Info
NR1H2
ENSG00000131408.15 NR1H2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H2hg38_v1_chr19_+_50376447_50376518-0.188.7e-03Click!

Activity profile of NR1H2 motif

Sorted Z-values of NR1H2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_237004440 7.44 ENST00000464121.3
MT1HL1
metallothionein 1H like 1
chr3_-_195583931 6.95 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
APOD
apolipoprotein D
chr10_-_70888546 5.65 ENST00000299299.4
PCBD1
pterin-4 alpha-carbinolamine dehydratase 1
chr15_+_96332432 5.23 ENST00000559679.1
ENST00000394171.6
NR2F2
nuclear receptor subfamily 2 group F member 2
chr15_+_96333111 5.03 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2 group F member 2
chr2_+_222861059 4.95 ENST00000681697.1
ENST00000680921.1
ACSL3
acyl-CoA synthetase long chain family member 3
chr20_+_36092698 4.70 ENST00000430276.5
ENST00000373950.6
ENST00000373946.7
ENST00000441639.5
ENST00000628415.2
ENST00000452261.5
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr2_+_222861005 4.53 ENST00000680147.1
ENST00000681009.1
ENST00000679514.1
ENST00000357430.8
ACSL3
acyl-CoA synthetase long chain family member 3
chr2_+_222860942 4.39 ENST00000392066.7
ENST00000680251.1
ENST00000679541.1
ENST00000679545.1
ENST00000680395.1
ACSL3
acyl-CoA synthetase long chain family member 3
chr17_-_37359076 4.23 ENST00000621960.1
ENST00000614428.4
ENST00000614789.4
ACACA
acetyl-CoA carboxylase alpha
chr20_+_36091409 3.93 ENST00000202028.9
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr3_-_98522869 3.90 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
CLDND1
claudin domain containing 1
chr11_+_123590939 3.81 ENST00000646146.1
GRAMD1B
GRAM domain containing 1B
chr7_-_73738792 3.63 ENST00000222800.8
ENST00000458339.6
ABHD11
abhydrolase domain containing 11
chr3_-_98523013 3.44 ENST00000394181.6
ENST00000508902.5
ENST00000394180.6
CLDND1
claudin domain containing 1
chr3_-_98522514 3.37 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
CLDND1
claudin domain containing 1
chr4_+_38867789 3.34 ENST00000358869.5
FAM114A1
family with sequence similarity 114 member A1
chr7_-_73738831 3.32 ENST00000395147.9
ENST00000437775.7
ABHD11
abhydrolase domain containing 11
chr8_+_131904071 3.27 ENST00000254624.10
ENST00000522709.5
EFR3A
EFR3 homolog A
chr17_-_19745602 3.26 ENST00000444455.5
ENST00000439102.6
ALDH3A1
aldehyde dehydrogenase 3 family member A1
chr11_+_10305065 3.20 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
ADM
adrenomedullin
chr4_-_687325 3.16 ENST00000503156.5
SLC49A3
solute carrier family 49 member 3
chr7_+_153887081 3.10 ENST00000404039.5
DPP6
dipeptidyl peptidase like 6
chr3_-_139539679 2.98 ENST00000483943.6
ENST00000672186.1
ENST00000232219.6
ENST00000617459.4
ENST00000492918.1
RBP1
retinol binding protein 1
chr12_+_57520959 2.96 ENST00000551351.5
MBD6
methyl-CpG binding domain protein 6
chr12_-_91179472 2.94 ENST00000550099.5
ENST00000546391.5
DCN
decorin
chr12_-_55728994 2.93 ENST00000257857.9
CD63
CD63 molecule
chr12_-_55728977 2.92 ENST00000552164.5
CD63
CD63 molecule
chr12_-_55729660 2.73 ENST00000546457.1
ENST00000549117.5
CD63
CD63 molecule
chr8_-_28083920 2.70 ENST00000413272.7
NUGGC
nuclear GTPase, germinal center associated
chr19_+_15641280 2.68 ENST00000585846.1
CYP4F3
cytochrome P450 family 4 subfamily F member 3
chr14_-_21536928 2.62 ENST00000613414.4
SALL2
spalt like transcription factor 2
chr7_-_56092932 2.59 ENST00000446428.5
ENST00000432123.5
ENST00000297373.7
PHKG1
phosphorylase kinase catalytic subunit gamma 1
chr14_-_21537206 2.57 ENST00000614342.1
SALL2
spalt like transcription factor 2
chr11_+_87037820 2.53 ENST00000340353.11
TMEM135
transmembrane protein 135
chr20_+_19758245 2.44 ENST00000255006.12
RIN2
Ras and Rab interactor 2
chr11_+_26332117 2.31 ENST00000531646.1
ENST00000256737.8
ANO3
anoctamin 3
chr16_-_19522062 2.28 ENST00000353258.8
GDE1
glycerophosphodiester phosphodiesterase 1
chr19_-_8514146 2.19 ENST00000255616.8
ENST00000393927.9
ZNF414
zinc finger protein 414
chr7_-_56092974 2.19 ENST00000452681.6
ENST00000537360.5
PHKG1
phosphorylase kinase catalytic subunit gamma 1
chr17_+_79022908 2.17 ENST00000354124.7
ENST00000580454.5
C1QTNF1
C1q and TNF related 1
chr7_+_100539188 2.15 ENST00000300176.9
AGFG2
ArfGAP with FG repeats 2
chr11_+_66509079 2.10 ENST00000419755.3
ENSG00000256349.1
novel protein
chr10_-_68527498 2.09 ENST00000609923.6
SLC25A16
solute carrier family 25 member 16
chr12_-_113403873 2.06 ENST00000552280.5
ENST00000257549.9
SDS
serine dehydratase
chr19_+_7903843 2.00 ENST00000397981.7
ENST00000397979.4
ENST00000397983.7
MAP2K7
mitogen-activated protein kinase kinase 7
chr14_-_53954470 1.98 ENST00000417573.5
BMP4
bone morphogenetic protein 4
chr11_+_87037915 1.91 ENST00000526733.5
ENST00000305494.6
ENST00000532959.5
TMEM135
transmembrane protein 135
chr17_-_17577440 1.90 ENST00000395782.5
PEMT
phosphatidylethanolamine N-methyltransferase
chr19_-_57916577 1.89 ENST00000598629.5
ENST00000595559.1
ENST00000312026.6
ENST00000597515.5
ZNF417
zinc finger protein 417
chr8_-_120445092 1.88 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr14_-_21536884 1.86 ENST00000546363.5
SALL2
spalt like transcription factor 2
chr1_+_223701582 1.82 ENST00000433674.6
CAPN2
calpain 2
chr20_-_33674359 1.81 ENST00000606690.5
ENST00000439478.5
ENST00000246190.11
ENST00000375238.8
NECAB3
N-terminal EF-hand calcium binding protein 3
chr19_+_41262656 1.80 ENST00000599719.5
ENST00000601309.5
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U like 1
chr1_+_169368175 1.78 ENST00000367808.8
ENST00000426663.1
BLZF1
basic leucine zipper nuclear factor 1
chr19_-_15934521 1.76 ENST00000402119.9
CYP4F11
cytochrome P450 family 4 subfamily F member 11
chr10_-_125823089 1.73 ENST00000368774.1
ENST00000368778.7
ENST00000649536.1
UROS
uroporphyrinogen III synthase
chr16_-_1611985 1.72 ENST00000426508.7
IFT140
intraflagellar transport 140
chr3_+_46242371 1.68 ENST00000545097.1
CCR3
C-C motif chemokine receptor 3
chr1_+_23791203 1.56 ENST00000374503.7
ENST00000374502.7
LYPLA2
lysophospholipase 2
chr11_+_844406 1.56 ENST00000397404.5
TSPAN4
tetraspanin 4
chr19_+_15640880 1.56 ENST00000586182.6
ENST00000221307.13
ENST00000591058.5
CYP4F3
cytochrome P450 family 4 subfamily F member 3
chr3_-_49856526 1.54 ENST00000331456.7
ENST00000482243.1
ENST00000469027.5
TRAIP
TRAF interacting protein
chr4_-_82562240 1.54 ENST00000515780.6
TMEM150C
transmembrane protein 150C
chr11_-_798261 1.53 ENST00000530360.2
ENST00000531437.5
ENST00000628067.3
SLC25A22
solute carrier family 25 member 22
chr9_+_133061981 1.49 ENST00000372080.8
CEL
carboxyl ester lipase
chr11_-_35419213 1.48 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
SLC1A2
solute carrier family 1 member 2
chrX_+_21855987 1.46 ENST00000429584.3
YY2
YY2 transcription factor
chr19_+_15737985 1.45 ENST00000641646.1
OR10H3
olfactory receptor family 10 subfamily H member 3
chr19_+_15673069 1.45 ENST00000550308.6
ENST00000551607.5
CYP4F12
cytochrome P450 family 4 subfamily F member 12
chr19_-_45792755 1.44 ENST00000377735.7
ENST00000270223.7
DMWD
DM1 locus, WD repeat containing
chr19_+_52274443 1.44 ENST00000600821.5
ENST00000595149.5
ENST00000595000.5
ENST00000593612.1
ZNF766
zinc finger protein 766
chr2_+_73214233 1.43 ENST00000389501.9
ENST00000629411.2
SMYD5
SMYD family member 5
chr19_-_38315919 1.39 ENST00000591755.5
ENST00000337679.12
ENST00000339413.11
YIF1B
Yip1 interacting factor homolog B, membrane trafficking protein
chr3_+_46880242 1.37 ENST00000418619.5
PTH1R
parathyroid hormone 1 receptor
chr17_+_34356472 1.33 ENST00000225844.7
CCL13
C-C motif chemokine ligand 13
chr5_-_83673544 1.31 ENST00000503117.1
ENST00000510978.5
HAPLN1
hyaluronan and proteoglycan link protein 1
chr11_-_35420050 1.30 ENST00000395753.6
ENST00000395750.6
ENST00000645634.1
SLC1A2
solute carrier family 1 member 2
chr14_-_70359630 1.30 ENST00000389912.7
COX16
cytochrome c oxidase assembly factor COX16
chr10_+_80078646 1.29 ENST00000372277.7
ENST00000613758.4
ENST00000372281.8
ENST00000372275.5
ENST00000372274.5
TMEM254
transmembrane protein 254
chr13_-_32538683 1.28 ENST00000674456.1
ENST00000504114.5
N4BP2L2
NEDD4 binding protein 2 like 2
chr17_-_51120855 1.27 ENST00000618113.4
ENST00000357122.8
ENST00000262013.12
SPAG9
sperm associated antigen 9
chr12_-_55688891 1.26 ENST00000557555.2
ITGA7
integrin subunit alpha 7
chr19_+_16143678 1.26 ENST00000613986.4
ENST00000593031.1
HSH2D
hematopoietic SH2 domain containing
chr11_-_35419462 1.20 ENST00000643522.1
SLC1A2
solute carrier family 1 member 2
chr2_+_27032938 1.19 ENST00000238788.14
ENST00000404032.7
TMEM214
transmembrane protein 214
chr1_-_2003780 1.18 ENST00000682832.1
CFAP74
cilia and flagella associated protein 74
chr1_-_161238223 1.18 ENST00000515452.1
NR1I3
nuclear receptor subfamily 1 group I member 3
chr16_-_31135699 1.17 ENST00000317508.11
ENST00000568261.5
ENST00000567797.1
PRSS8
serine protease 8
chr4_-_79326008 1.17 ENST00000286794.5
NAA11
N-alpha-acetyltransferase 11, NatA catalytic subunit
chrX_+_30230657 1.12 ENST00000361644.4
MAGEB3
MAGE family member B3
chr1_-_169367746 1.11 ENST00000367811.8
ENST00000472647.5
NME7
NME/NM23 family member 7
chr1_+_169367934 1.10 ENST00000367807.7
ENST00000329281.6
ENST00000420531.1
BLZF1
basic leucine zipper nuclear factor 1
chr1_+_52142044 1.09 ENST00000287727.8
ENST00000371591.2
ZFYVE9
zinc finger FYVE-type containing 9
chr17_+_7281711 1.08 ENST00000317370.13
ENST00000571308.5
SLC2A4
solute carrier family 2 member 4
chr9_-_104928139 1.08 ENST00000423487.6
ENST00000374733.1
ENST00000374736.8
ENST00000678995.1
ABCA1
ATP binding cassette subfamily A member 1
chr11_-_35419542 1.08 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
SLC1A2
solute carrier family 1 member 2
chr6_-_2971594 1.08 ENST00000643098.1
SERPINB6
serpin family B member 6
chr1_+_81800906 1.07 ENST00000674393.1
ENST00000674208.1
ADGRL2
adhesion G protein-coupled receptor L2
chr12_-_120327762 1.07 ENST00000308366.9
ENST00000423423.3
PLA2G1B
phospholipase A2 group IB
chr14_+_77320996 1.06 ENST00000361389.8
ENST00000554279.5
ENST00000557639.5
ENST00000349555.7
ENST00000216465.10
ENST00000556627.5
ENST00000557053.5
GSTZ1
glutathione S-transferase zeta 1
chr1_+_26177482 1.05 ENST00000361530.11
ENST00000374253.9
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr10_-_74163 1.04 ENST00000564130.2
TUBB8
tubulin beta 8 class VIII
chr2_+_44275473 1.02 ENST00000260649.11
SLC3A1
solute carrier family 3 member 1
chr17_+_4771878 1.02 ENST00000270560.4
TM4SF5
transmembrane 4 L six family member 5
chr12_-_214146 1.02 ENST00000684302.1
SLC6A12
solute carrier family 6 member 12
chr4_-_82561972 0.99 ENST00000454948.3
ENST00000449862.7
TMEM150C
transmembrane protein 150C
chr19_-_22215746 0.99 ENST00000650058.1
ZNF676
zinc finger protein 676
chr1_+_156369202 0.99 ENST00000537040.6
RHBG
Rh family B glycoprotein
chr11_+_64924673 0.98 ENST00000164133.7
ENST00000532850.1
PPP2R5B
protein phosphatase 2 regulatory subunit B'beta
chr8_+_141391989 0.98 ENST00000520105.5
ENST00000523147.5
ENST00000521578.6
PTP4A3
protein tyrosine phosphatase 4A3
chr1_+_86993009 0.98 ENST00000370548.3
ENSG00000267561.2
novel protein
chr13_+_24160740 0.97 ENST00000382095.8
SPATA13
spermatogenesis associated 13
chr5_-_59356962 0.96 ENST00000405755.6
PDE4D
phosphodiesterase 4D
chr7_+_29806483 0.95 ENST00000409123.5
ENST00000242140.9
WIPF3
WAS/WASL interacting protein family member 3
chr6_-_2971558 0.95 ENST00000380539.7
ENST00000380546.7
SERPINB6
serpin family B member 6
chr12_-_7018465 0.94 ENST00000261407.9
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr12_-_213656 0.91 ENST00000359674.8
SLC6A12
solute carrier family 6 member 12
chr6_-_2971644 0.90 ENST00000644388.1
ENST00000380520.6
SERPINB6
serpin family B member 6
chr2_+_100562941 0.89 ENST00000264254.11
PDCL3
phosducin like 3
chr3_+_39329764 0.88 ENST00000414803.1
CCR8
C-C motif chemokine receptor 8
chr16_+_72008588 0.87 ENST00000572887.5
ENST00000219240.9
ENST00000574309.5
ENST00000576145.1
DHODH
dihydroorotate dehydrogenase (quinone)
chr19_+_8418386 0.87 ENST00000602117.1
MARCHF2
membrane associated ring-CH-type finger 2
chr1_-_161238196 0.86 ENST00000367983.9
ENST00000506209.5
ENST00000367980.6
ENST00000628566.2
NR1I3
nuclear receptor subfamily 1 group I member 3
chr7_+_123845048 0.86 ENST00000488323.5
ENST00000223026.9
HYAL4
hyaluronidase 4
chr1_+_150364621 0.85 ENST00000401000.8
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr1_-_13155961 0.85 ENST00000624207.1
PRAMEF26
PRAME family member 26
chr12_+_100200779 0.84 ENST00000188312.7
ENST00000546902.5
ENST00000552376.5
ENST00000551617.1
ACTR6
actin related protein 6
chr11_-_35420017 0.84 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
SLC1A2
solute carrier family 1 member 2
chr2_+_112977998 0.83 ENST00000259205.5
ENST00000376489.6
IL36G
interleukin 36 gamma
chr17_-_28368012 0.81 ENST00000555059.2
ENSG00000273171.1
novel protein, readthrough between VTN and SEBOX
chr21_-_36060242 0.81 ENST00000443703.1
ENST00000399207.5
ENST00000399215.5
SETD4
SET domain containing 4
chr17_-_555648 0.79 ENST00000679817.1
ENST00000681858.1
ENST00000681103.1
VPS53
VPS53 subunit of GARP complex
chr11_-_62754141 0.77 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
ZBTB3
zinc finger and BTB domain containing 3
chr19_+_16719841 0.75 ENST00000524140.7
NWD1
NACHT and WD repeat domain containing 1
chr2_-_216081759 0.74 ENST00000265322.8
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr4_-_39032343 0.73 ENST00000381938.4
TMEM156
transmembrane protein 156
chr8_+_737595 0.71 ENST00000637795.2
DLGAP2
DLG associated protein 2
chr9_-_128067310 0.64 ENST00000373078.5
NAIF1
nuclear apoptosis inducing factor 1
chr17_-_43900596 0.64 ENST00000377184.7
MPP2
membrane palmitoylated protein 2
chr12_+_6970904 0.63 ENST00000599672.6
ENST00000539196.2
EMG1
EMG1 N1-specific pseudouridine methyltransferase
chr1_-_161238163 0.63 ENST00000367982.8
NR1I3
nuclear receptor subfamily 1 group I member 3
chr14_-_22644352 0.62 ENST00000540461.2
OR6J1
olfactory receptor family 6 subfamily J member 1
chr1_-_12945416 0.61 ENST00000415464.6
PRAMEF6
PRAME family member 6
chr4_+_122339221 0.61 ENST00000442707.1
KIAA1109
KIAA1109
chr1_-_2003808 0.60 ENST00000493964.5
CFAP74
cilia and flagella associated protein 74
chr16_-_31094727 0.60 ENST00000300851.10
ENST00000394975.3
VKORC1
vitamin K epoxide reductase complex subunit 1
chr15_+_64094060 0.58 ENST00000560829.5
SNX1
sorting nexin 1
chr21_-_36060300 0.58 ENST00000442559.5
ENST00000399205.5
ENST00000429161.5
ENST00000424303.5
ENST00000399208.6
SETD4
SET domain containing 4
chr11_-_7963646 0.57 ENST00000328600.3
NLRP10
NLR family pyrin domain containing 10
chr1_+_13303539 0.57 ENST00000437300.2
PRAMEF33
PRAME family member 33
chr11_+_64241600 0.56 ENST00000535135.7
ENST00000652094.1
FKBP2
FKBP prolyl isomerase 2
chr1_+_209827964 0.56 ENST00000491415.7
UTP25
UTP25 small subunit processor component
chr3_+_139343996 0.55 ENST00000680020.1
ENST00000310776.9
ENST00000465373.5
MRPS22
mitochondrial ribosomal protein S22
chr21_-_36060466 0.55 ENST00000399212.5
ENST00000332131.9
ENST00000446166.5
SETD4
SET domain containing 4
chr3_+_39329700 0.52 ENST00000326306.5
CCR8
C-C motif chemokine receptor 8
chr16_+_30699155 0.52 ENST00000262518.9
SRCAP
Snf2 related CREBBP activator protein
chr19_+_15793951 0.49 ENST00000308940.8
OR10H5
olfactory receptor family 10 subfamily H member 5
chr15_-_43584504 0.49 ENST00000348806.10
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr13_-_32538819 0.48 ENST00000674452.1
ENST00000674422.1
ENST00000674349.1
ENST00000674465.1
ENST00000674327.1
ENST00000505213.5
ENST00000357505.10
ENST00000399396.7
N4BP2L2
NEDD4 binding protein 2 like 2
chr19_-_45639104 0.44 ENST00000586770.5
ENST00000591721.5
ENST00000245925.8
ENST00000590043.5
ENST00000589876.5
EML2
EMAP like 2
chr11_+_119168705 0.42 ENST00000409109.6
ENST00000409991.5
ENST00000292199.6
NLRX1
NLR family member X1
chrX_-_2929324 0.41 ENST00000381154.6
ARSD
arylsulfatase D
chr19_+_18097763 0.41 ENST00000262811.10
MAST3
microtubule associated serine/threonine kinase 3
chr17_-_2266131 0.40 ENST00000570606.5
ENST00000354901.8
SMG6
SMG6 nonsense mediated mRNA decay factor
chr18_-_69956924 0.38 ENST00000581982.5
ENST00000280200.8
CD226
CD226 molecule
chrX_-_154292117 0.38 ENST00000610938.1
TEX28
testis expressed 28
chr9_-_84340743 0.38 ENST00000376238.5
SLC28A3
solute carrier family 28 member 3
chr20_-_41300066 0.38 ENST00000436099.6
ENST00000309060.7
ENST00000373261.5
ENST00000436440.6
ENST00000560364.5
ENST00000560361.5
ZHX3
zinc fingers and homeoboxes 3
chr4_+_182243394 0.35 ENST00000511685.6
TENM3
teneurin transmembrane protein 3
chrX_-_72714181 0.34 ENST00000339490.7
ENST00000541944.5
ENST00000373539.3
PHKA1
phosphorylase kinase regulatory subunit alpha 1
chr19_-_51065067 0.33 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
KLK13
kallikrein related peptidase 13
chr7_-_76618300 0.32 ENST00000441393.1
POMZP3
POM121 and ZP3 fusion
chr12_-_213338 0.31 ENST00000424061.6
SLC6A12
solute carrier family 6 member 12
chr19_+_38433676 0.30 ENST00000359596.8
ENST00000355481.8
RYR1
ryanodine receptor 1
chr11_+_119168188 0.30 ENST00000454811.5
ENST00000409265.8
ENST00000449394.5
NLRX1
NLR family member X1
chr19_+_32581178 0.29 ENST00000590247.7
ENST00000419343.7
ENST00000592786.5
ENST00000379316.3
PDCD5
programmed cell death 5
chr19_-_49155130 0.25 ENST00000595625.1
HRC
histidine rich calcium binding protein
chr1_+_1281224 0.24 ENST00000400928.7
SCNN1D
sodium channel epithelial 1 subunit delta
chr1_-_165698863 0.22 ENST00000354775.4
ALDH9A1
aldehyde dehydrogenase 9 family member A1
chr13_+_49110309 0.21 ENST00000398316.7
FNDC3A
fibronectin type III domain containing 3A
chr1_+_100352451 0.21 ENST00000361544.11
ENST00000370124.8
ENST00000336454.5
CDC14A
cell division cycle 14A
chr11_+_32829903 0.20 ENST00000257836.4
PRRG4
proline rich and Gla domain 4
chr12_+_22625075 0.20 ENST00000671733.1
ENST00000335148.8
ENST00000672951.1
ENST00000266517.9
ETNK1
ethanolamine kinase 1
chr17_+_8310220 0.18 ENST00000583529.1
ENST00000361926.8
ARHGEF15
Rho guanine nucleotide exchange factor 15
chr15_+_43826961 0.17 ENST00000381246.6
ENST00000452115.1
ENST00000263795.11
WDR76
WD repeat domain 76
chr13_-_36370171 0.16 ENST00000355182.8
SPART
spartin
chr11_-_35419899 0.12 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
SLC1A2
solute carrier family 1 member 2
chr12_+_22625182 0.11 ENST00000538218.2
ETNK1
ethanolamine kinase 1
chr15_+_71810539 0.10 ENST00000617575.5
ENST00000621098.1
NR2E3
nuclear receptor subfamily 2 group E member 3
chr4_+_107989714 0.07 ENST00000505878.4
ENST00000603302.5
ENST00000638621.1
HADH
hydroxyacyl-CoA dehydrogenase
chr15_+_43371062 0.07 ENST00000260383.11
ENST00000564079.6
TUBGCP4
tubulin gamma complex associated protein 4
chr9_-_96302170 0.06 ENST00000375263.8
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr15_+_74318553 0.06 ENST00000558821.5
ENST00000268082.4
CCDC33
coiled-coil domain containing 33
chr2_+_227164607 0.05 ENST00000396578.8
COL4A3
collagen type IV alpha 3 chain
chr12_+_123458092 0.05 ENST00000526639.3
SNRNP35
small nuclear ribonucleoprotein U11/U12 subunit 35
chr8_-_123737378 0.05 ENST00000419625.6
ENST00000262219.10
ANXA13
annexin A13
chr2_+_206765578 0.03 ENST00000403094.3
ENST00000402774.8
FASTKD2
FAST kinase domains 2
chr22_+_35717872 0.02 ENST00000249044.2
APOL5
apolipoprotein L5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 13.9 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
2.6 10.3 GO:0009956 radial pattern formation(GO:0009956)
2.3 7.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.9 5.7 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.8 4.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.8 2.3 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.7 5.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.7 2.0 GO:0048392 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.6 3.2 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.6 2.6 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.6 8.6 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.6 1.8 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.4 1.3 GO:0002434 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) response to cyclosporin A(GO:1905237)
0.4 2.2 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.4 1.7 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.4 6.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 1.2 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.4 1.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.3 2.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.3 1.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 1.0 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 0.9 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 1.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 2.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.9 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 2.0 GO:0035897 proteolysis in other organism(GO:0035897)
0.2 3.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 1.0 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.2 0.7 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.2 1.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 1.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.2 1.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 1.0 GO:1990822 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.1 1.3 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 8.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 4.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.1 1.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 5.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 0.4 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.4 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.1 2.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 1.8 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 2.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 1.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.2 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.1 2.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.0 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.1 0.6 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 4.0 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 2.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.5 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035) negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.6 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 0.3 GO:0035803 egg coat formation(GO:0035803)
0.1 0.9 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 1.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.4 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 1.8 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 1.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.9 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 7.1 GO:0021915 neural tube development(GO:0021915)
0.0 1.5 GO:0034694 response to prostaglandin(GO:0034694)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 1.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 3.1 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 2.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 2.7 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 3.3 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.0 3.3 GO:0051591 response to cAMP(GO:0051591)
0.0 1.7 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.6 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 1.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 5.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 1.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 2.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 19.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 1.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 7.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.2 GO:0031415 NatA complex(GO:0031415)
0.2 3.0 GO:0010369 chromocenter(GO:0010369)
0.1 0.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 6.0 GO:0030673 axolemma(GO:0030673)
0.1 1.0 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.8 GO:1990745 EARP complex(GO:1990745)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.7 GO:0005883 neurofilament(GO:0005883)
0.1 0.3 GO:1990425 junctional membrane complex(GO:0030314) ryanodine receptor complex(GO:1990425)
0.1 4.3 GO:0031526 brush border membrane(GO:0031526)
0.1 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.8 GO:0005682 U5 snRNP(GO:0005682)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 4.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 3.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.4 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 8.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 3.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
1.4 5.6 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.8 4.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.6 1.9 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.6 13.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.5 3.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.5 5.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.5 1.5 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.5 1.5 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.5 2.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4 2.7 GO:0004882 androgen receptor activity(GO:0004882)
0.4 1.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 1.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.4 6.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 2.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.4 1.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.4 1.1 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.3 3.0 GO:0019841 retinol binding(GO:0019841)
0.3 1.5 GO:0004771 sterol esterase activity(GO:0004771)
0.3 2.2 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.3 1.4 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.3 10.3 GO:0001972 retinoic acid binding(GO:0001972)
0.3 1.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 0.7 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 2.0 GO:0039706 co-receptor binding(GO:0039706)
0.2 0.9 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2 3.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 2.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.4 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 1.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:1990460 leptin receptor binding(GO:1990460)
0.1 1.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.6 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 2.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 6.0 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0032190 acrosin binding(GO:0032190)
0.1 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 1.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 9.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.0 GO:0030506 ankyrin binding(GO:0030506)
0.0 4.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 2.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.9 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 3.2 GO:0005179 hormone activity(GO:0005179)
0.0 2.1 GO:0015297 antiporter activity(GO:0015297)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 1.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.0 PID IL3 PATHWAY IL3-mediated signaling events
0.1 8.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 4.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 3.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.0 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 ST ADRENERGIC Adrenergic Pathway
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 18.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 5.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 8.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 2.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 7.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 9.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 11.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 8.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 4.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 2.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 5.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling