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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR1I3

Z-value: 0.55

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
NR1I3
ENSG00000143257.12 NR1I3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I3hg38_v1_chr1_-_161238085_161238111-0.211.7e-03Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_+_73151833 7.38 ENST00000456643.5
ENST00000257497.11
ENST00000415424.5
ANXA1
annexin A1
chr6_+_32439866 4.84 ENST00000374982.5
ENST00000395388.7
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr2_-_208254232 4.12 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
IDH1
isocitrate dehydrogenase (NADP(+)) 1
chr1_+_153357846 4.03 ENST00000368738.4
S100A9
S100 calcium binding protein A9
chr11_-_82900406 3.29 ENST00000313010.8
ENST00000393399.6
ENST00000680437.1
PRCP
prolylcarboxypeptidase
chr1_-_225428813 2.75 ENST00000338179.6
ENST00000425080.1
LBR
lamin B receptor
chr17_-_64506616 2.71 ENST00000581697.5
ENST00000450599.7
ENST00000577922.6
DDX5
DEAD-box helicase 5
chr9_-_72953047 2.69 ENST00000297785.8
ENST00000376939.5
ALDH1A1
aldehyde dehydrogenase 1 family member A1
chr17_-_64506281 2.68 ENST00000225792.10
ENST00000585060.5
DDX5
DEAD-box helicase 5
chr1_-_45542726 2.68 ENST00000676549.1
PRDX1
peroxiredoxin 1
chr5_+_53560627 2.57 ENST00000296684.10
ENST00000506765.1
NDUFS4
NADH:ubiquinone oxidoreductase subunit S4
chr7_+_143381907 2.45 ENST00000392910.6
ZYX
zyxin
chr18_-_21704763 2.34 ENST00000580981.5
ENST00000289119.7
ABHD3
abhydrolase domain containing 3, phospholipase
chr17_+_34255274 2.31 ENST00000580907.5
ENST00000225831.4
CCL2
C-C motif chemokine ligand 2
chr7_+_143381561 2.25 ENST00000354434.8
ZYX
zyxin
chr14_+_52707178 2.22 ENST00000612399.4
PSMC6
proteasome 26S subunit, ATPase 6
chr14_+_52707192 2.19 ENST00000445930.7
ENST00000555339.5
ENST00000556813.1
PSMC6
proteasome 26S subunit, ATPase 6
chr1_-_23559490 2.15 ENST00000374561.6
ID3
inhibitor of DNA binding 3, HLH protein
chr1_-_205321737 2.13 ENST00000367157.6
NUAK2
NUAK family kinase 2
chr15_+_96332432 2.06 ENST00000559679.1
ENST00000394171.6
NR2F2
nuclear receptor subfamily 2 group F member 2
chr16_-_46689145 2.04 ENST00000299138.12
VPS35
VPS35 retromer complex component
chr19_-_6604083 1.93 ENST00000597430.2
CD70
CD70 molecule
chr19_-_48390847 1.89 ENST00000597017.5
KDELR1
KDEL endoplasmic reticulum protein retention receptor 1
chr17_-_40648646 1.73 ENST00000643318.1
SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr15_+_96333111 1.63 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2 group F member 2
chr6_-_31541937 1.54 ENST00000456662.5
ENST00000431908.5
ENST00000456976.5
ENST00000428450.5
ENST00000418897.5
ENST00000396172.6
ENST00000419020.1
ENST00000428098.5
DDX39B
DExD-box helicase 39B
chr4_+_70028452 1.29 ENST00000530128.5
ENST00000381057.3
ENST00000673563.1
HTN3
histatin 3
chr18_-_23586422 1.22 ENST00000269228.10
NPC1
NPC intracellular cholesterol transporter 1
chr19_+_676385 1.09 ENST00000166139.9
FSTL3
follistatin like 3
chr18_-_21703688 1.09 ENST00000584464.1
ENST00000578270.5
ABHD3
abhydrolase domain containing 3, phospholipase
chr18_-_26090584 0.95 ENST00000415083.7
SS18
SS18 subunit of BAF chromatin remodeling complex
chr11_+_64241600 0.90 ENST00000535135.7
ENST00000652094.1
FKBP2
FKBP prolyl isomerase 2
chr14_-_21536884 0.86 ENST00000546363.5
SALL2
spalt like transcription factor 2
chr3_-_58433810 0.83 ENST00000474765.1
ENST00000485460.5
ENST00000302746.11
ENST00000383714.8
PDHB
pyruvate dehydrogenase E1 subunit beta
chr16_-_66934144 0.81 ENST00000568572.5
CIAO2B
cytosolic iron-sulfur assembly component 2B
chrX_-_15600953 0.76 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
ACE2
angiotensin I converting enzyme 2
chr10_-_80172839 0.73 ENST00000265447.8
ANXA11
annexin A11
chr18_-_26091175 0.72 ENST00000579061.5
ENST00000542420.6
SS18
SS18 subunit of BAF chromatin remodeling complex
chr19_+_54201122 0.70 ENST00000391753.6
ENST00000441429.1
RPS9
ribosomal protein S9
chr16_-_66934362 0.69 ENST00000567511.1
ENST00000422424.7
CIAO2B
cytosolic iron-sulfur assembly component 2B
chrX_+_111681118 0.68 ENST00000371979.7
ENST00000610588.4
ENST00000251943.8
ENST00000621367.4
ENST00000394780.8
ENST00000473389.5
ENST00000622986.3
ENST00000623255.1
ALG13
ALG13 UDP-N-acetylglucosaminyltransferase subunit
chr1_+_43935807 0.67 ENST00000438616.3
ARTN
artemin
chr10_+_133160401 0.65 ENST00000684739.1
ENST00000682765.1
ENST00000683144.1
ENST00000683259.1
ENST00000682399.1
ENST00000368571.3
KNDC1
kinase non-catalytic C-lobe domain containing 1
chr16_+_67873036 0.60 ENST00000358933.10
EDC4
enhancer of mRNA decapping 4
chr7_-_73738792 0.59 ENST00000222800.8
ENST00000458339.6
ABHD11
abhydrolase domain containing 11
chr7_-_73738831 0.57 ENST00000395147.9
ENST00000437775.7
ABHD11
abhydrolase domain containing 11
chr7_+_101127095 0.53 ENST00000223095.5
SERPINE1
serpin family E member 1
chr2_-_86563382 0.50 ENST00000263856.9
CHMP3
charged multivesicular body protein 3
chr6_-_56394094 0.50 ENST00000370819.5
COL21A1
collagen type XXI alpha 1 chain
chr19_+_54200849 0.49 ENST00000626547.2
ENST00000302907.9
ENST00000391752.5
ENST00000402367.5
ENST00000391751.7
RPS9
ribosomal protein S9
chr8_+_11494367 0.44 ENST00000259089.9
ENST00000529894.1
BLK
BLK proto-oncogene, Src family tyrosine kinase
chr9_+_37486006 0.41 ENST00000377792.3
POLR1E
RNA polymerase I subunit E
chr11_-_7963646 0.41 ENST00000328600.3
NLRP10
NLR family pyrin domain containing 10
chr12_-_118372883 0.41 ENST00000542532.5
ENST00000392533.8
TAOK3
TAO kinase 3
chr9_+_131125973 0.35 ENST00000651639.1
ENST00000451030.5
ENST00000531584.1
NUP214
nucleoporin 214
chr4_-_81215185 0.33 ENST00000264399.6
PRKG2
protein kinase cGMP-dependent 2
chrX_+_111681650 0.33 ENST00000436609.5
ENST00000482742.5
ENST00000623189.1
ALG13
ALG13 UDP-N-acetylglucosaminyltransferase subunit
chr2_-_39120383 0.31 ENST00000395038.6
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1
chr6_+_96521796 0.30 ENST00000369278.5
UFL1
UFM1 specific ligase 1
chr1_+_32465046 0.26 ENST00000609129.2
ZBTB8B
zinc finger and BTB domain containing 8B
chr5_-_39270623 0.25 ENST00000512138.1
ENST00000646045.2
FYB1
FYN binding protein 1
chr12_+_100200779 0.23 ENST00000188312.7
ENST00000546902.5
ENST00000552376.5
ENST00000551617.1
ACTR6
actin related protein 6
chr15_+_84980440 0.22 ENST00000310298.8
ENST00000557957.5
PDE8A
phosphodiesterase 8A
chr16_+_527698 0.19 ENST00000219611.7
ENST00000562370.5
ENST00000568988.5
CAPN15
calpain 15
chr22_+_30607203 0.19 ENST00000407817.3
TCN2
transcobalamin 2
chr1_-_53220589 0.19 ENST00000294360.5
CZIB
CXXC motif containing zinc binding protein
chr4_-_81214960 0.18 ENST00000395578.3
ENST00000628926.1
PRKG2
protein kinase cGMP-dependent 2
chr14_-_102509713 0.17 ENST00000286918.9
ANKRD9
ankyrin repeat domain 9
chr7_-_99735093 0.14 ENST00000611620.4
ENST00000620220.6
ENST00000336374.4
CYP3A7-CYP3A51P
CYP3A7
CYP3A7-CYP3A51P readthrough
cytochrome P450 family 3 subfamily A member 7
chr12_+_57604598 0.11 ENST00000548804.5
ENST00000550596.5
ENST00000551835.5
ENST00000549583.5
DTX3
deltex E3 ubiquitin ligase 3
chr14_+_22508602 0.10 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr17_-_58219227 0.10 ENST00000581180.2
ENST00000313863.11
ENST00000393119.7
ENST00000678463.1
ENST00000676787.1
ENST00000580127.6
ENST00000585134.2
ENST00000581761.6
MKS1
MKS transition zone complex subunit 1
chr1_-_27356471 0.09 ENST00000486046.5
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr16_-_16223467 0.08 ENST00000575728.1
ENST00000574094.6
ENST00000205557.12
ABCC6
ATP binding cassette subfamily C member 6
chrX_+_129738942 0.08 ENST00000371106.4
XPNPEP2
X-prolyl aminopeptidase 2
chr2_-_68871382 0.08 ENST00000295379.2
BMP10
bone morphogenetic protein 10
chr14_+_94026314 0.07 ENST00000203664.10
ENST00000553723.1
OTUB2
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr19_-_15449920 0.07 ENST00000263381.12
ENST00000643092.1
ENST00000673675.1
WIZ
WIZ zinc finger
chr3_+_122384167 0.06 ENST00000232125.9
ENST00000477892.5
ENST00000469967.1
FAM162A
family with sequence similarity 162 member A
chr17_+_46295099 0.05 ENST00000393465.7
ENST00000320254.5
LRRC37A
leucine rich repeat containing 37A
chr17_+_28506320 0.05 ENST00000579795.6
FOXN1
forkhead box N1
chr1_+_154405193 0.04 ENST00000622330.4
ENST00000344086.8
IL6R
interleukin 6 receptor
chr1_-_158426237 0.04 ENST00000641042.1
OR10K2
olfactory receptor family 10 subfamily K member 2
chr1_-_145918485 0.03 ENST00000537888.1
PEX11B
peroxisomal biogenesis factor 11 beta
chr5_-_177509814 0.02 ENST00000510898.7
ENST00000502885.5
ENST00000506493.5
DOK3
docking protein 3
chr3_-_115071333 0.01 ENST00000462705.5
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_154405326 0.01 ENST00000368485.8
IL6R
interleukin 6 receptor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0036292 DNA rewinding(GO:0036292)
1.6 4.8 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.4 4.1 GO:0006097 glyoxylate cycle(GO:0006097)
1.0 4.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.9 3.7 GO:0009956 radial pattern formation(GO:0009956)
0.8 2.3 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.7 2.0 GO:1903336 positive regulation of Wnt protein secretion(GO:0061357) regulation of late endosome to lysosome transport(GO:1902822) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of vacuolar transport(GO:1903336)
0.4 2.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.4 3.3 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.3 5.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 1.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 4.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 1.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.5 GO:0001300 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.2 1.5 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 0.4 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.7 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.8 GO:0002005 angiotensin catabolic process in blood(GO:0002005) angiotensin-mediated drinking behavior(GO:0003051)
0.1 1.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 2.2 GO:0030903 notochord development(GO:0030903)
0.1 0.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 2.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 3.4 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.3 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 1.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 1.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 1.7 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.3 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 2.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 2.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.7 GO:0032506 cytokinetic process(GO:0032506)
0.0 4.7 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 2.6 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.0 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.7 2.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.4 4.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 4.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 1.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 5.4 GO:0071141 SMAD protein complex(GO:0071141)
0.1 2.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.5 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.9 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 3.4 GO:0071564 npBAF complex(GO:0071564)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 4.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.8 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 4.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 2.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.4 4.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
1.3 4.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.1 3.4 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.9 2.8 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.9 5.4 GO:0035500 MH2 domain binding(GO:0035500)
0.8 2.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.6 1.9 GO:0005046 KDEL sequence binding(GO:0005046)
0.5 4.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 2.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 4.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 1.0 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.3 2.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 0.8 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 1.5 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 1.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 3.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 3.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 2.0 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.1 GO:0048185 activin binding(GO:0048185)
0.1 1.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 2.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.9 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 4.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 4.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.9 PID ARF 3PATHWAY Arf1 pathway
0.1 2.3 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 3.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 7.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 5.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 4.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 2.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 7.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 3.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex