Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for NR2F2
Z-value: 0.13
Motif logo
Transcription factors associated with NR2F2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NR2F2
|
ENSG00000185551.15 | NR2F2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NR2F2 | hg38_v1_chr15_+_96332432_96332565 | 0.23 | 5.5e-04 | Click! |
Activity profile of NR2F2 motif
Sorted Z-values of NR2F2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of NR2F2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 4.1 | GO:1902957 | negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957) |
| 3.8 | 18.8 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 3.0 | 8.9 | GO:0002086 | diaphragm contraction(GO:0002086) |
| 1.9 | 7.5 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 1.7 | 5.2 | GO:0043323 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 1.7 | 17.2 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 1.7 | 10.0 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
| 1.3 | 3.8 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 1.3 | 5.0 | GO:1902283 | negative regulation of primary amine oxidase activity(GO:1902283) |
| 1.2 | 4.9 | GO:0001519 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 1.2 | 3.6 | GO:0002892 | type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) |
| 1.1 | 5.3 | GO:0044789 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 1.1 | 3.2 | GO:1902460 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 1.0 | 9.4 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.9 | 3.7 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.9 | 2.7 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 0.9 | 4.3 | GO:0044856 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 0.8 | 2.5 | GO:0072334 | UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334) |
| 0.8 | 2.5 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 0.8 | 6.5 | GO:0052405 | negative regulation by host of symbiont molecular function(GO:0052405) |
| 0.8 | 5.6 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.8 | 2.3 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.8 | 2.3 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 0.7 | 4.4 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.7 | 2.9 | GO:0046223 | mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) |
| 0.7 | 2.1 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 0.7 | 6.1 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 0.7 | 6.7 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 0.7 | 2.0 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
| 0.6 | 2.6 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 0.6 | 1.9 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.6 | 2.5 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.6 | 2.5 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.6 | 0.6 | GO:0060701 | negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) |
| 0.6 | 2.4 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 0.6 | 2.4 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.6 | 1.8 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.6 | 2.3 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.6 | 7.9 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.6 | 7.2 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.5 | 1.1 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 0.5 | 4.6 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.5 | 3.5 | GO:1901315 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.5 | 1.5 | GO:1900155 | positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
| 0.5 | 8.7 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.5 | 3.7 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 0.4 | 4.4 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.4 | 2.6 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.4 | 1.3 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
| 0.4 | 1.3 | GO:1902490 | regulation of sperm capacitation(GO:1902490) |
| 0.4 | 2.1 | GO:1990418 | response to insulin-like growth factor stimulus(GO:1990418) |
| 0.4 | 7.7 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.4 | 1.7 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 0.4 | 2.5 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.4 | 2.0 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 0.4 | 1.2 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 0.4 | 1.2 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.4 | 1.9 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.4 | 4.5 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.4 | 2.2 | GO:0045631 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.4 | 1.4 | GO:0032764 | smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764) |
| 0.4 | 1.4 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.4 | 2.8 | GO:0070236 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.3 | 1.0 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.3 | 7.9 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.3 | 6.8 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.3 | 1.7 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.3 | 1.0 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.3 | 2.5 | GO:0030647 | polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
| 0.3 | 1.0 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
| 0.3 | 0.9 | GO:1901421 | generation of catalytic spliceosome for second transesterification step(GO:0000350) positive regulation of response to alcohol(GO:1901421) |
| 0.3 | 2.5 | GO:0015705 | iodide transport(GO:0015705) |
| 0.3 | 0.9 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 0.3 | 0.9 | GO:0051793 | medium-chain fatty acid catabolic process(GO:0051793) |
| 0.3 | 5.4 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.3 | 19.9 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.3 | 0.8 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.3 | 4.2 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.3 | 0.8 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 0.3 | 1.8 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.3 | 1.8 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 0.2 | 1.2 | GO:0090118 | receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) |
| 0.2 | 0.7 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 0.2 | 2.1 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.2 | 0.7 | GO:0042822 | pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) |
| 0.2 | 2.0 | GO:1990668 | vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668) |
| 0.2 | 1.7 | GO:0016255 | protein retention in ER lumen(GO:0006621) attachment of GPI anchor to protein(GO:0016255) |
| 0.2 | 0.6 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.2 | 4.2 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.2 | 0.6 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 0.2 | 0.8 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.2 | 1.2 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 0.2 | 7.1 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.2 | 0.8 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.2 | 0.6 | GO:0001545 | primary ovarian follicle growth(GO:0001545) |
| 0.2 | 2.1 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.2 | 1.1 | GO:1903862 | positive regulation of oxidative phosphorylation(GO:1903862) |
| 0.2 | 1.1 | GO:0015853 | adenine transport(GO:0015853) |
| 0.2 | 3.4 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.2 | 0.5 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 0.2 | 0.5 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.2 | 0.5 | GO:0090521 | regulation of embryonic cell shape(GO:0016476) glomerular visceral epithelial cell migration(GO:0090521) |
| 0.2 | 5.2 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.2 | 1.2 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.2 | 1.3 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.2 | 0.6 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.2 | 1.1 | GO:0046322 | negative regulation of fatty acid oxidation(GO:0046322) |
| 0.2 | 1.1 | GO:1903895 | negative regulation of IRE1-mediated unfolded protein response(GO:1903895) |
| 0.2 | 0.3 | GO:0003213 | cardiac right atrium morphogenesis(GO:0003213) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) |
| 0.1 | 11.8 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.1 | 2.4 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 0.7 | GO:0001766 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.1 | 0.6 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 0.1 | 0.1 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.1 | 2.2 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 5.7 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.1 | 8.8 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.1 | 2.5 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.1 | 1.3 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.1 | 1.1 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
| 0.1 | 0.5 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 0.1 | 0.2 | GO:0000472 | endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471) |
| 0.1 | 0.8 | GO:0045047 | protein targeting to ER(GO:0045047) |
| 0.1 | 0.4 | GO:0090675 | intermicrovillar adhesion(GO:0090675) |
| 0.1 | 1.1 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.1 | 0.4 | GO:0061163 | endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650) |
| 0.1 | 3.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.5 | GO:0006231 | dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073) |
| 0.1 | 0.3 | GO:0071169 | establishment of protein localization to chromatin(GO:0071169) |
| 0.1 | 1.6 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 1.7 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 1.0 | GO:0090151 | establishment of protein localization to mitochondrial membrane(GO:0090151) |
| 0.1 | 0.6 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 0.1 | 1.0 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.1 | 0.6 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.1 | 0.9 | GO:0043382 | regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) |
| 0.1 | 1.2 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.1 | 0.4 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 0.1 | 0.8 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.1 | 0.8 | GO:0048478 | replication fork protection(GO:0048478) |
| 0.1 | 0.3 | GO:0006145 | purine nucleobase catabolic process(GO:0006145) vitamin B6 metabolic process(GO:0042816) xanthine metabolic process(GO:0046110) |
| 0.1 | 1.0 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.1 | 0.5 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.1 | 0.4 | GO:0044407 | biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) |
| 0.1 | 9.6 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.1 | 1.2 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.1 | 3.9 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.1 | 1.7 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.1 | 1.1 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 1.4 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 0.1 | 0.5 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 1.0 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.1 | 1.8 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
| 0.1 | 0.7 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.1 | 0.3 | GO:0043375 | negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
| 0.1 | 1.2 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) |
| 0.1 | 1.0 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.1 | 2.1 | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.1 | 0.6 | GO:1901299 | negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299) |
| 0.1 | 2.6 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.1 | 0.7 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.1 | 0.7 | GO:1904714 | chaperone-mediated autophagy(GO:0061684) regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.1 | 1.2 | GO:0009125 | nucleoside monophosphate catabolic process(GO:0009125) |
| 0.1 | 1.4 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.1 | 0.2 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.1 | 2.3 | GO:0002183 | cytoplasmic translational initiation(GO:0002183) |
| 0.1 | 2.2 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.1 | 4.7 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.1 | 2.8 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.1 | 0.8 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
| 0.1 | 0.2 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 0.1 | 2.0 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.1 | 1.3 | GO:0006582 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
| 0.1 | 0.2 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.1 | 3.0 | GO:0031102 | neuron projection regeneration(GO:0031102) |
| 0.1 | 0.8 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.1 | 0.7 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.1 | 4.8 | GO:0006901 | vesicle coating(GO:0006901) |
| 0.1 | 0.4 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 1.5 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.1 | 0.8 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.1 | 1.0 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.1 | 4.2 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.1 | 0.6 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.1 | 0.2 | GO:1901253 | negative regulation of intracellular transport of viral material(GO:1901253) |
| 0.1 | 0.5 | GO:0060215 | primitive hemopoiesis(GO:0060215) |
| 0.1 | 0.9 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 0.6 | GO:0045634 | regulation of melanocyte differentiation(GO:0045634) |
| 0.0 | 0.5 | GO:0050665 | hydrogen peroxide biosynthetic process(GO:0050665) |
| 0.0 | 1.9 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.0 | 3.4 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 6.0 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.0 | 0.1 | GO:2000197 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
| 0.0 | 1.3 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.0 | 0.5 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.0 | 0.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 0.3 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.0 | 0.7 | GO:0006144 | purine nucleobase metabolic process(GO:0006144) |
| 0.0 | 0.7 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 1.5 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.8 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 3.7 | GO:0006413 | translational initiation(GO:0006413) |
| 0.0 | 0.2 | GO:0086048 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) membrane depolarization during bundle of His cell action potential(GO:0086048) |
| 0.0 | 0.5 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.0 | 1.1 | GO:0043928 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 0.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.4 | GO:0017004 | cytochrome complex assembly(GO:0017004) |
| 0.0 | 3.2 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 0.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 1.7 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
| 0.0 | 0.5 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 0.0 | 0.7 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 0.2 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.0 | 0.6 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.0 | 1.7 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.3 | GO:0006296 | nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) |
| 0.0 | 0.1 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.0 | 0.4 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.0 | 0.8 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.0 | 1.1 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.0 | 0.1 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.0 | 0.4 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 1.5 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.8 | GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) negative regulation of ubiquitin protein ligase activity(GO:1904667) |
| 0.0 | 0.1 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 0.0 | 0.1 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.0 | 0.1 | GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.0 | 2.2 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 1.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 0.6 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.0 | 0.3 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.0 | 1.4 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 0.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.0 | 0.1 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.0 | 0.8 | GO:0071230 | cellular response to amino acid stimulus(GO:0071230) |
| 0.0 | 1.7 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 1.0 | GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068) |
| 0.0 | 0.5 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 0.3 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 0.2 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.0 | 0.3 | GO:0042255 | ribosome assembly(GO:0042255) |
| 0.0 | 0.1 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.0 | 0.3 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 9.4 | GO:0071750 | dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) |
| 1.7 | 5.1 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
| 1.6 | 17.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 1.0 | 7.1 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.9 | 3.7 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.9 | 4.6 | GO:0001652 | granular component(GO:0001652) |
| 0.8 | 6.7 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.8 | 7.8 | GO:0044754 | autolysosome(GO:0044754) |
| 0.8 | 4.6 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.6 | 2.4 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 0.6 | 3.5 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.5 | 2.7 | GO:0031523 | Myb complex(GO:0031523) |
| 0.5 | 11.3 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.5 | 7.1 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.4 | 2.6 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
| 0.4 | 1.7 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.4 | 1.3 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 0.4 | 4.2 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.4 | 4.4 | GO:0005638 | lamin filament(GO:0005638) |
| 0.4 | 2.0 | GO:0042825 | TAP complex(GO:0042825) |
| 0.4 | 2.7 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 0.4 | 7.9 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.4 | 1.8 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.4 | 3.6 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.4 | 1.1 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 0.3 | 1.0 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.3 | 1.7 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.3 | 1.0 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.3 | 1.3 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.3 | 1.5 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.3 | 4.8 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.3 | 4.7 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.3 | 4.3 | GO:0030478 | actin cap(GO:0030478) |
| 0.3 | 3.3 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.3 | 0.8 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.3 | 1.1 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.2 | 0.7 | GO:0097224 | sperm connecting piece(GO:0097224) |
| 0.2 | 1.6 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.2 | 28.4 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.2 | 14.1 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.2 | 2.4 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.2 | 0.8 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.2 | 1.7 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.2 | 21.9 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.2 | 12.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 1.7 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.2 | 1.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.2 | 1.9 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.2 | 1.3 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.2 | 1.9 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.2 | 1.1 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.2 | 1.4 | GO:0032797 | SMN complex(GO:0032797) |
| 0.1 | 3.7 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 0.7 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.1 | 15.8 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 1.4 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.1 | 0.7 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.1 | 2.1 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 1.9 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 4.8 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.1 | 1.4 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 0.7 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.1 | 2.0 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 10.3 | GO:0005902 | microvillus(GO:0005902) |
| 0.1 | 0.4 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 0.8 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.1 | 5.1 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 5.1 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 1.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.1 | 7.0 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 0.8 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 0.7 | GO:1903439 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.1 | 0.7 | GO:0098574 | cytoplasmic side of lysosomal membrane(GO:0098574) |
| 0.1 | 0.5 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.1 | 0.8 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.1 | 0.9 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
| 0.1 | 7.9 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 1.3 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 0.2 | GO:0030689 | Noc complex(GO:0030689) |
| 0.1 | 5.9 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 1.3 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.1 | 1.1 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 2.1 | GO:0005761 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.1 | 0.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.1 | 2.9 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 0.9 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.1 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.2 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 2.4 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 1.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 2.7 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 0.5 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.1 | 0.9 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 1.2 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.0 | 0.8 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.5 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.2 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.0 | 16.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866) |
| 0.0 | 3.1 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 0.6 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.5 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 2.2 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 2.4 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 1.3 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 4.1 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.3 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 4.2 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 4.2 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 1.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.8 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 0.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 2.0 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 1.0 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 1.2 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 15.5 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 9.4 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 1.0 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 3.8 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.1 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.5 | GO:0044447 | axoneme part(GO:0044447) |
| 0.0 | 0.3 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.1 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 0.3 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 0.2 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 0.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 1.6 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.0 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.2 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.0 | GO:0038201 | TOR complex(GO:0038201) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 10.0 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 2.5 | 7.5 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 1.4 | 4.3 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 1.3 | 5.0 | GO:0052596 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
| 1.2 | 6.2 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 1.2 | 4.9 | GO:0004598 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 1.1 | 4.3 | GO:0032450 | maltose alpha-glucosidase activity(GO:0032450) |
| 0.8 | 4.2 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.8 | 2.5 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.8 | 6.7 | GO:0004308 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
| 0.8 | 2.3 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 0.7 | 5.8 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.7 | 2.1 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 0.7 | 6.1 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.7 | 2.0 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 0.7 | 3.4 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.7 | 2.0 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.7 | 2.0 | GO:0000035 | acyl binding(GO:0000035) |
| 0.6 | 2.6 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
| 0.6 | 2.5 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
| 0.6 | 2.4 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 0.6 | 2.4 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.6 | 1.8 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.6 | 2.3 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.6 | 1.7 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 0.6 | 3.4 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.5 | 2.7 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.5 | 1.6 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.5 | 3.7 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.5 | 2.6 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
| 0.5 | 8.4 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.5 | 1.8 | GO:0016972 | flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972) |
| 0.4 | 1.7 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.4 | 1.3 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 0.4 | 2.5 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.4 | 1.2 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.4 | 3.8 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.3 | 3.4 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.3 | 2.8 | GO:0043426 | MRF binding(GO:0043426) |
| 0.3 | 2.2 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.3 | 4.3 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.3 | 3.0 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.3 | 4.8 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.3 | 12.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.3 | 8.8 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.3 | 1.4 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.3 | 0.9 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
| 0.3 | 1.1 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.3 | 17.3 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.3 | 2.4 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.3 | 1.1 | GO:0005471 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 0.3 | 2.1 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.3 | 14.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.3 | 1.3 | GO:0004803 | transposase activity(GO:0004803) |
| 0.2 | 0.7 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.2 | 1.4 | GO:0008381 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.2 | 0.9 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.2 | 2.3 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.2 | 3.4 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.2 | 0.7 | GO:0031403 | lithium ion binding(GO:0031403) |
| 0.2 | 2.0 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.2 | 4.9 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.2 | 0.9 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.2 | 0.4 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.2 | 1.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.2 | 1.1 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.2 | 0.9 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.2 | 1.5 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.2 | 11.1 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.2 | 1.2 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.2 | 2.8 | GO:0031386 | protein tag(GO:0031386) |
| 0.2 | 1.0 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.2 | 0.6 | GO:0004963 | follicle-stimulating hormone receptor activity(GO:0004963) |
| 0.2 | 1.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.2 | 1.9 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.2 | 0.8 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.2 | 1.9 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.2 | 7.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 1.0 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 0.7 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.1 | 2.1 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 0.1 | 1.4 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 1.0 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.1 | 0.6 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.1 | 5.8 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.1 | 0.8 | GO:0000285 | 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) |
| 0.1 | 0.8 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 1.1 | GO:0089720 | caspase binding(GO:0089720) |
| 0.1 | 4.5 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 0.1 | 0.6 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.1 | 10.2 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 3.7 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.1 | 12.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.5 | GO:0070905 | serine binding(GO:0070905) |
| 0.1 | 1.1 | GO:0034485 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) |
| 0.1 | 3.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.6 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 1.5 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.1 | 2.1 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.1 | 0.3 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.1 | 1.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 3.1 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 7.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 0.7 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.1 | 2.5 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 0.6 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.1 | 1.8 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.1 | 2.4 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.1 | 1.2 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 1.6 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 0.9 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 3.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 0.5 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.1 | 1.3 | GO:0004549 | tRNA-specific ribonuclease activity(GO:0004549) |
| 0.1 | 0.9 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 1.1 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.1 | 0.5 | GO:0031705 | bombesin receptor binding(GO:0031705) |
| 0.1 | 2.0 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.1 | 2.3 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.1 | 0.7 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.1 | 2.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 0.6 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.1 | 1.0 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 2.8 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 0.3 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.1 | 0.5 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.1 | 0.5 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 0.5 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.1 | 1.3 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.1 | 5.0 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.1 | 3.5 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.1 | 1.7 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 0.9 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 2.9 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 0.4 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 4.8 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 5.9 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.2 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.0 | 1.8 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.1 | GO:0000992 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
| 0.0 | 1.9 | GO:0061650 | ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.0 | 0.8 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.8 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.3 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 2.1 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 0.2 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 0.3 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.0 | 1.2 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 0.0 | 4.3 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.2 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.0 | 0.3 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.0 | 1.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.9 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.0 | 0.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.5 | GO:0019841 | retinal binding(GO:0016918) retinol binding(GO:0019841) |
| 0.0 | 0.6 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 0.3 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 6.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 2.4 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 3.0 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.1 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
| 0.0 | 0.4 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 1.4 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
| 0.0 | 0.1 | GO:0015119 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 0.0 | 0.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.0 | 0.2 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 7.0 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 2.0 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 3.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.2 | GO:0004559 | alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923) |
| 0.0 | 3.0 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 1.2 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 0.1 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.0 | 0.9 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 1.3 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.6 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 1.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.2 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 1.0 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.4 | GO:0046961 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 1.4 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.3 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 1.2 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.7 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.2 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.0 | 0.1 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.0 | 1.5 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.1 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 0.0 | 0.1 | GO:0047238 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 6.1 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.2 | 4.5 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.2 | 8.0 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 1.1 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.1 | 13.2 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.1 | 3.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 8.2 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.1 | 3.6 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 2.8 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 5.6 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.1 | 7.5 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 8.5 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 7.7 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 4.2 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.1 | 3.7 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 4.1 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 18.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.0 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.1 | 2.4 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 5.4 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 1.6 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 1.1 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 3.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 1.3 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 0.5 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.1 | 1.6 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.2 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 11.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 3.5 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 1.4 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 1.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 1.3 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 2.4 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 2.8 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.0 | 2.4 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.7 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 1.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 4.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.3 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.5 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 0.2 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.5 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.8 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 17.2 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.6 | 5.1 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.5 | 9.1 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.4 | 8.3 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.4 | 6.1 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.2 | 8.1 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.2 | 9.2 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.2 | 4.8 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.2 | 1.9 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.2 | 3.1 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.2 | 4.2 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.2 | 9.5 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.2 | 13.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.2 | 4.8 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.2 | 2.3 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 1.3 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.1 | 12.3 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.1 | 3.5 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 3.2 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 7.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 5.0 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 2.3 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 2.9 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 3.7 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 2.7 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 2.3 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 4.4 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 5.2 | REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
| 0.1 | 1.9 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.1 | 1.1 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.1 | 1.3 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 2.3 | REACTOME LIPOPROTEIN METABOLISM | Genes involved in Lipoprotein metabolism |
| 0.1 | 1.3 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.1 | 1.1 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 3.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 1.6 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.1 | 1.7 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.1 | 0.9 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 2.1 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.1 | 0.8 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.1 | 0.6 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.0 | 1.3 | REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 0.0 | 1.3 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 1.3 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.0 | 0.8 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 2.0 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 6.2 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.0 | 0.6 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.0 | 2.5 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |
| 0.0 | 0.6 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.7 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.5 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.0 | 0.5 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.2 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 0.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 3.1 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.7 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 2.7 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.6 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.6 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 1.0 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.3 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |