avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
NR4A2 Links Ensembl NCBI GeneCards UniProt	ENSG00000153234.15	NR4A2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NR4A2	hg38_v1_chr2_-_156342348_156342466	-0.28	2.0e-05	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr8_+_144095054 Show fit	30.34	ENST00000318911.5	CYC1 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c1
chr2_-_175181663 Show fit	18.41	ENST00000392541.3 ENST00000284727.9 ENST00000409194.5	ATP5MC3 Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase membrane subunit c locus 3
chr10_+_79347491 Show fit	17.43	ENST00000448165.1	PPIF Links Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase F
chr11_-_64246907 Show fit	13.83	ENST00000309318.8	PPP1R14B Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 14B
chr11_-_64246190 Show fit	13.04	ENST00000392210.6	PPP1R14B Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 14B
chr20_+_3796288 Show fit	13.01	ENST00000439880.6 ENST00000245960.10	CDC25B Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 25B
chr7_+_128758947 Show fit	12.59	ENST00000493278.1	CALU Links Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr10_+_79347460 Show fit	12.44	ENST00000225174.8	PPIF Links Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase F
chr5_-_134004635 Show fit	12.31	ENST00000425992.2 ENST00000395044.7 ENST00000395047.6	VDAC1 Links Ensembl NCBI GeneCards UniProt Show fit	voltage dependent anion channel 1
chr1_-_17054015 Show fit	11.51	ENST00000375499.8	SDHB Links Ensembl NCBI GeneCards UniProt Show fit	succinate dehydrogenase complex iron sulfur subunit B
chr21_+_41168142 Show fit	11.50	ENST00000330333.11	BACE2 Links Ensembl NCBI GeneCards UniProt Show fit	beta-secretase 2
chr3_-_167734465 Show fit	10.69	ENST00000487947.6	PDCD10 Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 10
chr2_-_206159509 Show fit	10.55	ENST00000423725.5	NDUFS1 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S1
chr17_+_81703356 Show fit	10.44	ENST00000333676.8 ENST00000571730.1	MRPL12 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000262660.1 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L12 novel protein
chr21_+_41167774 Show fit	10.35	ENST00000328735.10 ENST00000347667.5	BACE2 Links Ensembl NCBI GeneCards UniProt Show fit	beta-secretase 2
chr20_-_62143374 Show fit	10.28	ENST00000370873.9 ENST00000370858.3	PSMA7 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 7
chr19_-_10335773 Show fit	9.87	ENST00000592439.1	ICAM3 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr4_-_70839343 Show fit	9.73	ENST00000514161.5 ENST00000499044.6	GRSF1 Links Ensembl NCBI GeneCards UniProt Show fit	G-rich RNA sequence binding factor 1
chr1_+_32292067 Show fit	9.58	ENST00000373548.8 ENST00000428704.1	HDAC1 Links Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 1
chrX_-_110440218 Show fit	9.56	ENST00000372057.1 ENST00000372054.3	AMMECR1 Links Ensembl NCBI GeneCards UniProt Show fit GNG5P2 Links Ensembl NCBI GeneCards UniProt Show fit	AMMECR nuclear protein 1 G protein subunit gamma 5 pseudogene 2
chr2_-_206159410 Show fit	9.31	ENST00000457011.5 ENST00000440274.5 ENST00000432169.5 ENST00000233190.11	NDUFS1 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S1
chr15_-_55270280 Show fit	9.31	ENST00000564609.5	RAB27A Links Ensembl NCBI GeneCards UniProt Show fit	RAB27A, member RAS oncogene family
chr8_-_130016414 Show fit	9.28	ENST00000401979.6 ENST00000517654.5 ENST00000522361.1 ENST00000518167.5	CYRIB Links Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr7_+_39623547 Show fit	9.16	ENST00000005257.7	RALA Links Ensembl NCBI GeneCards UniProt Show fit	RAS like proto-oncogene A
chr13_+_30427950 Show fit	8.84	ENST00000436446.1	UBE2L5 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 L5
chr2_-_197499826 Show fit	8.76	ENST00000439605.2 ENST00000388968.8 ENST00000418022.2	HSPD1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family D (Hsp60) member 1
chr2_+_85577540 Show fit	8.70	ENST00000263864.10 ENST00000409760.1	VAMP8 Links Ensembl NCBI GeneCards UniProt Show fit	vesicle associated membrane protein 8
chr8_-_130016622 Show fit	8.66	ENST00000518283.5 ENST00000519110.5	CYRIB Links Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr1_+_67685342 Show fit	8.12	ENST00000617962.2	GADD45A Links Ensembl NCBI GeneCards UniProt Show fit	growth arrest and DNA damage inducible alpha
chr2_-_206159194 Show fit	8.01	ENST00000455934.6 ENST00000449699.5 ENST00000454195.1	NDUFS1 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S1
chr17_+_54900824 Show fit	7.98	ENST00000572405.5 ENST00000572158.5 ENST00000575882.6 ENST00000572298.5 ENST00000536554.5 ENST00000575333.5 ENST00000570499.5 ENST00000572576.5	TOM1L1 Links Ensembl NCBI GeneCards UniProt Show fit	target of myb1 like 1 membrane trafficking protein
chr15_-_55270383 Show fit	7.92	ENST00000396307.6	RAB27A Links Ensembl NCBI GeneCards UniProt Show fit	RAB27A, member RAS oncogene family
chr2_+_27212866 Show fit	7.78	ENST00000419744.1	ATRAID Links Ensembl NCBI GeneCards UniProt Show fit	all-trans retinoic acid induced differentiation factor
chr11_+_34916611 Show fit	7.67	ENST00000227868.9 ENST00000430469.6 ENST00000533262.1	PDHX Links Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehydrogenase complex component X
chr2_-_197499857 Show fit	7.65	ENST00000428204.6 ENST00000678170.1 ENST00000676933.1 ENST00000678621.1	HSPD1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family D (Hsp60) member 1
chr10_+_49942048 Show fit	7.46	ENST00000651259.3 ENST00000652716.1	TIMM23B Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 23 homolog B
chr8_-_130016395 Show fit	7.44	ENST00000523509.5	CYRIB Links Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr2_+_197500398 Show fit	7.40	ENST00000604458.1	HSPE1-MOB4 Links Ensembl NCBI GeneCards UniProt Show fit	HSPE1-MOB4 readthrough
chr1_-_241519701 Show fit	7.40	ENST00000366560.4 ENST00000683521.1	FH Links Ensembl NCBI GeneCards UniProt Show fit	fumarate hydratase
chr3_-_113746218 Show fit	7.25	ENST00000497255.1 ENST00000240922.8 ENST00000478020.1 ENST00000493900.5	NAA50 Links Ensembl NCBI GeneCards UniProt Show fit	N-alpha-acetyltransferase 50, NatE catalytic subunit
chr3_-_167734510 Show fit	7.23	ENST00000475915.6 ENST00000462725.6 ENST00000461494.5	PDCD10 Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 10
chr7_+_48089257 Show fit	7.22	ENST00000436673.5 ENST00000395564.9	UPP1 Links Ensembl NCBI GeneCards UniProt Show fit	uridine phosphorylase 1
chr1_+_155613221 Show fit	7.19	ENST00000462250.2	MSTO1 Links Ensembl NCBI GeneCards UniProt Show fit	misato mitochondrial distribution and morphology regulator 1
chr9_-_146140 Show fit	7.02	ENST00000475990.5	CBWD1 Links Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 1
chr1_+_155209213 Show fit	6.92	ENST00000609421.1	MTX1 Links Ensembl NCBI GeneCards UniProt Show fit	metaxin 1
chr16_-_69334871 Show fit	6.90	ENST00000562949.1	ENSG00000272617.3 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein, COG8-PDF readthrough
chr1_+_162561504 Show fit	6.83	ENST00000271469.7 ENST00000367926.8	UAP1 Links Ensembl NCBI GeneCards UniProt Show fit	UDP-N-acetylglucosamine pyrophosphorylase 1
chr10_+_45972482 Show fit	6.81	ENST00000580018.4	TIMM23 Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 23
chrX_-_130165699 Show fit	6.71	ENST00000676328.1 ENST00000675857.1 ENST00000675427.1 ENST00000675092.1	AIFM1 Links Ensembl NCBI GeneCards UniProt Show fit	apoptosis inducing factor mitochondria associated 1
chr4_-_102345469 Show fit	6.63	ENST00000356736.5 ENST00000682932.1	SLC39A8 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 8
chr3_-_113746185 Show fit	6.57	ENST00000616174.1	NAA50 Links Ensembl NCBI GeneCards UniProt Show fit	N-alpha-acetyltransferase 50, NatE catalytic subunit
chr8_+_144358974 Show fit	6.57	ENST00000526891.2	SLC52A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 52 member 2
chr4_-_73223082 Show fit	6.36	ENST00000509867.6	ANKRD17 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 17
chr10_+_14838288 Show fit	6.35	ENST00000640019.3 ENST00000493178.1 ENST00000378372.8	ENSG00000284024.4 Links Ensembl NCBI GeneCards UniProt Show fit HSPA14 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein heat shock protein family A (Hsp70) member 14
chr9_-_128127711 Show fit	6.01	ENST00000449878.1 ENST00000338961.11 ENST00000678174.1	PTGES2 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E synthase 2
chr19_-_7943648 Show fit	5.97	ENST00000597926.1 ENST00000270538.8	TIMM44 Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 44
chr7_+_48088596 Show fit	5.95	ENST00000416681.5 ENST00000331803.8 ENST00000432131.5	UPP1 Links Ensembl NCBI GeneCards UniProt Show fit	uridine phosphorylase 1
chr19_-_2328573 Show fit	5.82	ENST00000587502.2 ENST00000252622.15 ENST00000585409.2	LSM7 Links Ensembl NCBI GeneCards UniProt Show fit	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr2_+_197500371 Show fit	5.77	ENST00000409468.1 ENST00000233893.10	HSPE1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family E (Hsp10) member 1
chr17_+_28744034 Show fit	5.53	ENST00000444415.7 ENST00000262396.10	TRAF4 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 4
chr14_-_103921494 Show fit	5.52	ENST00000557040.5 ENST00000414262.6 ENST00000555030.5 ENST00000554713.2 ENST00000286953.8 ENST00000553430.5	ATP5MJ Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase membrane subunit j
chr7_-_73522278 Show fit	5.45	ENST00000404251.1 ENST00000339594.9	BAZ1B Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain adjacent to zinc finger domain 1B
chr19_+_46347063 Show fit	5.42	ENST00000012443.9 ENST00000391919.1	PPP5C Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 5 catalytic subunit
chr19_+_6739650 Show fit	5.38	ENST00000313285.12 ENST00000313244.14 ENST00000596758.5	TRIP10 Links Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor interactor 10
chr20_+_48921701 Show fit	5.31	ENST00000371917.5	ARFGEF2 Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor guanine nucleotide exchange factor 2
chr15_-_42491105 Show fit	5.18	ENST00000565380.5 ENST00000564754.7	ZNF106 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 106
chr3_+_138621225 Show fit	5.16	ENST00000479848.1	FAIM Links Ensembl NCBI GeneCards UniProt Show fit	Fas apoptotic inhibitory molecule
chr15_+_75043263 Show fit	5.07	ENST00000563393.1	PPCDC Links Ensembl NCBI GeneCards UniProt Show fit	phosphopantothenoylcysteine decarboxylase
chr22_+_29767351 Show fit	4.90	ENST00000330029.6 ENST00000401406.3	UQCR10 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquinol-cytochrome c reductase, complex III subunit X
chr1_+_201955496 Show fit	4.77	ENST00000367287.5	TIMM17A Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 17A
chr7_+_112423137 Show fit	4.77	ENST00000005558.8 ENST00000621379.4	IFRD1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon related developmental regulator 1
chr4_+_80197493 Show fit	4.74	ENST00000415738.3	PRDM8 Links Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 8
chr1_-_1779976 Show fit	4.67	ENST00000378625.5	NADK Links Ensembl NCBI GeneCards UniProt Show fit	NAD kinase
chr4_-_151015713 Show fit	4.56	ENST00000357115.9	LRBA Links Ensembl NCBI GeneCards UniProt Show fit	LPS responsive beige-like anchor protein
chr20_+_48921775 Show fit	4.55	ENST00000681021.1 ENST00000679436.1	ARFGEF2 Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor guanine nucleotide exchange factor 2
chr18_-_12377200 Show fit	4.54	ENST00000269143.8	AFG3L2 Links Ensembl NCBI GeneCards UniProt Show fit	AFG3 like matrix AAA peptidase subunit 2
chr4_-_110198650 Show fit	4.46	ENST00000394607.7	ELOVL6 Links Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 6
chr8_-_52714414 Show fit	4.32	ENST00000435644.6 ENST00000518710.5 ENST00000025008.10 ENST00000517963.1	RB1CC1 Links Ensembl NCBI GeneCards UniProt Show fit	RB1 inducible coiled-coil 1
chr16_+_56730099 Show fit	4.22	ENST00000563858.5 ENST00000566315.5 ENST00000308159.10 ENST00000569842.5 ENST00000569863.5	NUP93 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 93
chr7_+_39623886 Show fit	4.09	ENST00000436179.1	RALA Links Ensembl NCBI GeneCards UniProt Show fit	RAS like proto-oncogene A
chr10_+_22316445 Show fit	4.07	ENST00000448361.5	COMMD3 Links Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 3
chr2_+_233712905 Show fit	3.98	ENST00000373414.4	UGT1A5 Links Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A5
chr19_+_1407517 Show fit	3.95	ENST00000336761.10 ENST00000233078.9 ENST00000592522.5	DAZAP1 Links Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 1
chr5_-_138575359 Show fit	3.90	ENST00000297185.9 ENST00000678300.1 ENST00000677425.1 ENST00000677064.1 ENST00000507115.6	HSPA9 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family A (Hsp70) member 9
chr2_+_227813834 Show fit	3.89	ENST00000358813.5 ENST00000409189.7	CCL20 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 20
chr4_+_41612702 Show fit	3.73	ENST00000509277.5	LIMCH1 Links Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr3_+_138621207 Show fit	3.69	ENST00000464668.5	FAIM Links Ensembl NCBI GeneCards UniProt Show fit	Fas apoptotic inhibitory molecule
chr15_+_78149354 Show fit	3.58	ENST00000558554.5 ENST00000557826.5 ENST00000561279.5 ENST00000299518.7 ENST00000559186.5 ENST00000560770.5 ENST00000559881.5 ENST00000559205.1 ENST00000629769.2	IDH3A Links Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
chr3_+_179604785 Show fit	3.54	ENST00000611971.4 ENST00000493866.5 ENST00000259037.8 ENST00000472629.5 ENST00000482604.5	NDUFB5 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B5
chr10_+_22316375 Show fit	3.50	ENST00000376836.8 ENST00000456711.5 ENST00000444869.5 ENST00000475460.6 ENST00000602390.5 ENST00000489125.2	COMMD3 Links Ensembl NCBI GeneCards UniProt Show fit COMMD3-BMI1 Links Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 3 COMMD3-BMI1 readthrough
chr2_-_26244597 Show fit	3.48	ENST00000492433.2 ENST00000645274.1 ENST00000380649.8	HADHA Links Ensembl NCBI GeneCards UniProt Show fit	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
chr9_+_113221528 Show fit	3.46	ENST00000374212.5	SLC31A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 31 member 1
chr4_-_40515967 Show fit	3.41	ENST00000381795.10	RBM47 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 47
chr16_+_4624811 Show fit	3.41	ENST00000415496.5 ENST00000262370.12 ENST00000587747.5 ENST00000399577.9 ENST00000588994.5 ENST00000586183.5	MGRN1 Links Ensembl NCBI GeneCards UniProt Show fit	mahogunin ring finger 1
chr8_-_143944737 Show fit	3.36	ENST00000398774.6	PLEC Links Ensembl NCBI GeneCards UniProt Show fit	plectin
chr5_+_218241 Show fit	3.29	ENST00000617470.4 ENST00000504309.5 ENST00000510361.5 ENST00000264932.11	SDHA Links Ensembl NCBI GeneCards UniProt Show fit	succinate dehydrogenase complex flavoprotein subunit A
chr4_-_151015263 Show fit	3.17	ENST00000510413.5 ENST00000507224.5 ENST00000651943.2	LRBA Links Ensembl NCBI GeneCards UniProt Show fit	LPS responsive beige-like anchor protein
chr1_-_20661356 Show fit	3.14	ENST00000602624.7 ENST00000464364.1	DDOST Links Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr4_-_110198579 Show fit	3.14	ENST00000302274.8	ELOVL6 Links Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 6
chr14_+_23322019 Show fit	3.11	ENST00000557702.5	PABPN1 Links Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein nuclear 1
chr2_+_206159580 Show fit	3.11	ENST00000236957.9 ENST00000392221.5 ENST00000445505.5	EEF1B2 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 beta 2
chr4_-_138242325 Show fit	3.09	ENST00000280612.9	SLC7A11 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 11
chr22_+_31122923 Show fit	3.09	ENST00000620191.4 ENST00000412277.6 ENST00000412985.5 ENST00000331075.10 ENST00000420017.5 ENST00000400294.6 ENST00000405300.5 ENST00000404390.7	INPP5J Links Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-5-phosphatase J
chr2_+_108621260 Show fit	3.07	ENST00000409441.5	LIMS1 Links Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 1
chr17_+_28744002 Show fit	3.03	ENST00000618771.1 ENST00000262395.10 ENST00000422344.5	TRAF4 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 4
chr20_+_62143729 Show fit	3.02	ENST00000331758.8 ENST00000450482.5	SS18L1 Links Ensembl NCBI GeneCards UniProt Show fit	SS18L1 subunit of BAF chromatin remodeling complex
chr2_+_26244731 Show fit	2.97	ENST00000537713.5	HADHB Links Ensembl NCBI GeneCards UniProt Show fit	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr16_+_85908988 Show fit	2.95	ENST00000566369.1	IRF8 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 8
chr2_+_206159884 Show fit	2.94	ENST00000392222.7	EEF1B2 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 beta 2
chr1_+_212565334 Show fit	2.86	ENST00000366981.8 ENST00000366987.6	ATF3 Links Ensembl NCBI GeneCards UniProt Show fit	activating transcription factor 3
chr17_-_58280928 Show fit	2.83	ENST00000225275.4	MPO Links Ensembl NCBI GeneCards UniProt Show fit	myeloperoxidase
chr7_-_92246045 Show fit	2.81	ENST00000394507.5 ENST00000458177.6 ENST00000340022.6 ENST00000444960.5	KRIT1 Links Ensembl NCBI GeneCards UniProt Show fit	KRIT1 ankyrin repeat containing
chr19_+_1407653 Show fit	2.73	ENST00000587079.5	DAZAP1 Links Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 1
chr1_-_229434086 Show fit	2.68	ENST00000366684.7 ENST00000684723.1 ENST00000366683.4	ACTA1 Links Ensembl NCBI GeneCards UniProt Show fit	actin alpha 1, skeletal muscle
chr12_-_55728977 Show fit	2.67	ENST00000552164.5	CD63 Links Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chr5_-_150449731 Show fit	2.60	ENST00000407193.7	RPS14 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S14
chr7_+_112450451 Show fit	2.59	ENST00000429071.5 ENST00000403825.8 ENST00000675268.1	IFRD1 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000288634.1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon related developmental regulator 1 novel protein
chr20_+_19758245 Show fit	2.52	ENST00000255006.12	RIN2 Links Ensembl NCBI GeneCards UniProt Show fit	Ras and Rab interactor 2
chrX_-_21758021 Show fit	2.52	ENST00000646008.1	SMPX Links Ensembl NCBI GeneCards UniProt Show fit	small muscle protein X-linked
chr2_-_64019367 Show fit	2.50	ENST00000272322.9	VPS54 Links Ensembl NCBI GeneCards UniProt Show fit	VPS54 subunit of GARP complex
chr7_-_92245795 Show fit	2.49	ENST00000412043.6 ENST00000430102.5 ENST00000425073.1 ENST00000394505.7 ENST00000394503.6 ENST00000454017.5 ENST00000440209.5 ENST00000413688.5 ENST00000452773.5 ENST00000433016.5 ENST00000422347.5 ENST00000458493.5 ENST00000425919.5 ENST00000650585.1	KRIT1 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000285953.1 Links Ensembl NCBI GeneCards UniProt Show fit	KRIT1 ankyrin repeat containing novel protein
chr11_+_68030896 Show fit	2.45	ENST00000525628.1	NDUFS8 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S8
chr16_-_30526518 Show fit	2.44	ENST00000380412.7	ZNF768 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 768
chr9_-_93453540 Show fit	2.43	ENST00000375412.11	FAM120AOS Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 120A opposite strand
chr3_-_45958572 Show fit	2.32	ENST00000433878.5	FYCO1 Links Ensembl NCBI GeneCards UniProt Show fit	FYVE and coiled-coil domain autophagy adaptor 1
chr9_+_110668854 Show fit	2.30	ENST00000189978.10 ENST00000374440.7	MUSK Links Ensembl NCBI GeneCards UniProt Show fit	muscle associated receptor tyrosine kinase
chr8_-_99893697 Show fit	2.26	ENST00000518171.5 ENST00000520468.7	COX6C Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 6C
chr16_+_28931942 Show fit	2.22	ENST00000324662.8 ENST00000538922.8	CD19 Links Ensembl NCBI GeneCards UniProt Show fit	CD19 molecule
chr2_-_110115811 Show fit	2.09	ENST00000272462.3	MALL Links Ensembl NCBI GeneCards UniProt Show fit	mal, T cell differentiation protein like
chr2_+_233718734 Show fit	2.05	ENST00000373409.8	UGT1A4 Links Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A4
chr19_+_44891206 Show fit	2.01	ENST00000405636.6 ENST00000252487.9 ENST00000592434.5 ENST00000589649.1 ENST00000426677.7	TOMM40 Links Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 40
chrX_-_133415478 Show fit	1.99	ENST00000370828.4	GPC4 Links Ensembl NCBI GeneCards UniProt Show fit	glypican 4
chr17_-_81194028 Show fit	1.96	ENST00000570817.5	CEP131 Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 131
chr20_-_35411963 Show fit	1.93	ENST00000349714.9 ENST00000438533.5 ENST00000359226.6 ENST00000374384.6 ENST00000374385.10 ENST00000424405.5 ENST00000397554.5 ENST00000374380.6	UQCC1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquinol-cytochrome c reductase complex assembly factor 1
chr12_-_55728994 Show fit	1.92	ENST00000257857.9	CD63 Links Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chr12_-_56645955 Show fit	1.89	ENST00000552959.5 ENST00000551020.5 ENST00000553007.2 ENST00000262030.8	ATP5F1B Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase F1 subunit beta
chr14_+_22494810 Show fit	1.85	ENST00000390493.1	TRAJ44 Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 44
chrX_-_21758097 Show fit	1.85	ENST00000379494.4	SMPX Links Ensembl NCBI GeneCards UniProt Show fit	small muscle protein X-linked
chr22_-_42090743 Show fit	1.82	ENST00000498737.8 ENST00000617763.1	NDUFA6 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit A6
chr12_-_6606320 Show fit	1.78	ENST00000642594.1 ENST00000644289.1 ENST00000645095.1	CHD4 Links Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 4
chr5_-_150449676 Show fit	1.68	ENST00000312037.6	RPS14 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S14
chr11_-_9314564 Show fit	1.68	ENST00000611268.4 ENST00000528080.6 ENST00000527813.5 ENST00000533723.1	TMEM41B Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 41B
chr18_+_61333424 Show fit	1.68	ENST00000262717.9	CDH20 Links Ensembl NCBI GeneCards UniProt Show fit	cadherin 20
chr5_+_40679907 Show fit	1.67	ENST00000302472.4	PTGER4 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E receptor 4
chr4_-_98929092 Show fit	1.58	ENST00000280892.10 ENST00000511644.5 ENST00000504432.5 ENST00000450253.7 ENST00000505992.1	EIF4E Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4E
chr9_+_110668779 Show fit	1.56	ENST00000416899.7 ENST00000374448.9	MUSK Links Ensembl NCBI GeneCards UniProt Show fit	muscle associated receptor tyrosine kinase
chr13_+_32586443 Show fit	1.52	ENST00000315596.15	PDS5B Links Ensembl NCBI GeneCards UniProt Show fit	PDS5 cohesin associated factor B
chr7_-_151080833 Show fit	1.51	ENST00000353841.6 ENST00000482571.2	FASTK Links Ensembl NCBI GeneCards UniProt Show fit	Fas activated serine/threonine kinase
chr3_-_52826834 Show fit	1.45	ENST00000441637.2	ITIH4 Links Ensembl NCBI GeneCards UniProt Show fit	inter-alpha-trypsin inhibitor heavy chain 4
chr7_-_151080787 Show fit	1.42	ENST00000540185.5 ENST00000297532.11	FASTK Links Ensembl NCBI GeneCards UniProt Show fit	Fas activated serine/threonine kinase
chr11_+_122838492 Show fit	1.42	ENST00000227348.9	CRTAM Links Ensembl NCBI GeneCards UniProt Show fit	cytotoxic and regulatory T cell molecule
chrX_-_154412083 Show fit	1.42	ENST00000451865.5 ENST00000432135.1 ENST00000369809.5 ENST00000393638.5 ENST00000424626.5 ENST00000309585.9	DNASE1L1 Links Ensembl NCBI GeneCards UniProt Show fit	deoxyribonuclease 1 like 1
chr22_-_37484505 Show fit	1.38	ENST00000442496.1	MFNG Links Ensembl NCBI GeneCards UniProt Show fit	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_-_2711633 Show fit	1.37	ENST00000435359.5	CLUH Links Ensembl NCBI GeneCards UniProt Show fit	clustered mitochondria homolog
chr1_-_154192058 Show fit	1.31	ENST00000271850.11 ENST00000368530.7 ENST00000651641.1	TPM3 Links Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 3
chr17_-_10373002 Show fit	1.29	ENST00000252172.9 ENST00000418404.8	MYH13 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 13
chr17_-_2711736 Show fit	1.28	ENST00000651024.2 ENST00000576885.5 ENST00000574426.7	CLUH Links Ensembl NCBI GeneCards UniProt Show fit	clustered mitochondria homolog
chr6_+_139135063 Show fit	1.23	ENST00000367658.3	HECA Links Ensembl NCBI GeneCards UniProt Show fit	hdc homolog, cell cycle regulator
chr19_-_3062464 Show fit	1.21	ENST00000327141.9	TLE5 Links Ensembl NCBI GeneCards UniProt Show fit	TLE family member 5, transcriptional modulator
chr19_-_49049111 Show fit	1.20	ENST00000448456.4	CGB8 Links Ensembl NCBI GeneCards UniProt Show fit	chorionic gonadotropin subunit beta 8
chr1_+_206684887 Show fit	1.20	ENST00000367103.4 ENST00000294981.8	MAPKAPK2 Links Ensembl NCBI GeneCards UniProt Show fit	MAPK activated protein kinase 2
chr16_+_3654683 Show fit	1.20	ENST00000246949.10	DNASE1 Links Ensembl NCBI GeneCards UniProt Show fit	deoxyribonuclease 1
chr8_-_18083278 Show fit	1.13	ENST00000636691.1	ASAH1 Links Ensembl NCBI GeneCards UniProt Show fit	N-acylsphingosine amidohydrolase 1
chr7_-_81770039 Show fit	1.10	ENST00000222390.11 ENST00000453411.6 ENST00000457544.7 ENST00000444829.7	HGF Links Ensembl NCBI GeneCards UniProt Show fit	hepatocyte growth factor
chr1_+_103571077 Show fit	1.07	ENST00000610648.1	AMY2B Links Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 2B
chr21_-_33641721 Show fit	1.07	ENST00000399442.1 ENST00000413017.2 ENST00000445393.5 ENST00000417979.5 ENST00000381554.8 ENST00000426935.5 ENST00000381540.7 ENST00000361534.6	CRYZL1 Links Ensembl NCBI GeneCards UniProt Show fit	crystallin zeta like 1
chr7_-_151736304 Show fit	1.03	ENST00000492843.6	PRKAG2 Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit gamma 2
chr13_-_52011337 Show fit	0.96	ENST00000400366.6 ENST00000400370.8 ENST00000634844.1 ENST00000673772.1 ENST00000418097.7 ENST00000242839.10 ENST00000344297.9 ENST00000448424.7	ATP7B Links Ensembl NCBI GeneCards UniProt Show fit	ATPase copper transporting beta
chr5_+_177600104 Show fit	0.96	ENST00000029410.10 ENST00000510761.1 ENST00000505468.1	B4GALT7 Links Ensembl NCBI GeneCards UniProt Show fit	beta-1,4-galactosyltransferase 7
chr22_-_30564889 Show fit	0.95	ENST00000401975.5 ENST00000428682.5 ENST00000423299.5	GAL3ST1 Links Ensembl NCBI GeneCards UniProt Show fit	galactose-3-O-sulfotransferase 1
chr11_+_45805108 Show fit	0.95	ENST00000530471.1 ENST00000314134.4	SLC35C1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 member C1
chr7_-_81770122 Show fit	0.95	ENST00000423064.7	HGF Links Ensembl NCBI GeneCards UniProt Show fit	hepatocyte growth factor
chrX_-_63785510 Show fit	0.89	ENST00000437457.6 ENST00000374878.5 ENST00000623517.3	ARHGEF9 Links Ensembl NCBI GeneCards UniProt Show fit	Cdc42 guanine nucleotide exchange factor 9
chr3_-_151316795 Show fit	0.87	ENST00000260843.5	GPR87 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 87
chr19_-_35563653 Show fit	0.83	ENST00000262623.4	ATP4A Links Ensembl NCBI GeneCards UniProt Show fit	ATPase H+/K+ transporting subunit alpha
chr11_-_64744102 Show fit	0.83	ENST00000431822.5 ENST00000394432.8 ENST00000377486.7	RASGRP2 Links Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 2
chr20_-_37527862 Show fit	0.75	ENST00000373537.7 ENST00000445723.5 ENST00000414080.1	BLCAP Links Ensembl NCBI GeneCards UniProt Show fit	BLCAP apoptosis inducing factor
chr3_-_197298558 Show fit	0.68	ENST00000656944.1 ENST00000346964.6 ENST00000448528.6 ENST00000655488.1 ENST00000357674.9 ENST00000667157.1 ENST00000661336.1 ENST00000654737.1 ENST00000659716.1 ENST00000657381.1	DLG1 Links Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 1
chr17_+_81712236 Show fit	0.68	ENST00000545862.5 ENST00000350690.10 ENST00000331531.9	SLC25A10 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 10
chrX_-_155071064 Show fit	0.66	ENST00000369484.8 ENST00000369476.8	CMC4 Links Ensembl NCBI GeneCards UniProt Show fit MTCP1 Links Ensembl NCBI GeneCards UniProt Show fit	C-X9-C motif containing 4 mature T cell proliferation 1
chr11_-_66371728 Show fit	0.59	ENST00000357440.7 ENST00000619145.4	SLC29A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 29 member 2
chrX_+_106802660 Show fit	0.56	ENST00000357242.10 ENST00000310452.6 ENST00000481617.6 ENST00000276175.7	TBC1D8B Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 8B
chr19_-_15125095 Show fit	0.55	ENST00000600984.5	ILVBL Links Ensembl NCBI GeneCards UniProt Show fit	ilvB acetolactate synthase like
chr1_-_115768702 Show fit	0.55	ENST00000261448.6	CASQ2 Links Ensembl NCBI GeneCards UniProt Show fit	calsequestrin 2
chr8_-_99893135 Show fit	0.54	ENST00000524245.5	COX6C Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 6C
chr8_-_99893622 Show fit	0.54	ENST00000520271.5 ENST00000522940.5 ENST00000523016.1 ENST00000517682.6 ENST00000297564.6	COX6C Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 6C
chr7_+_2403567 Show fit	0.53	ENST00000258711.7 ENST00000618655.2	CHST12 Links Ensembl NCBI GeneCards UniProt Show fit	carbohydrate sulfotransferase 12
chr1_+_6034980 Show fit	0.52	ENST00000378092.6 ENST00000472700.7	KCNAB2 Links Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr14_-_24634160 Show fit	0.52	ENST00000616551.1 ENST00000382542.5 ENST00000216341.9 ENST00000526004.1 ENST00000415355.7	GZMB Links Ensembl NCBI GeneCards UniProt Show fit	granzyme B
chr7_+_73830988 Show fit	0.52	ENST00000340958.4	CLDN4 Links Ensembl NCBI GeneCards UniProt Show fit	claudin 4
chr6_+_106629560 Show fit	0.49	ENST00000369046.8	QRSL1 Links Ensembl NCBI GeneCards UniProt Show fit	glutaminyl-tRNA amidotransferase subunit QRSL1
chr3_+_159852933 Show fit	0.46	ENST00000482804.1	SCHIP1 Links Ensembl NCBI GeneCards UniProt Show fit	schwannomin interacting protein 1
chr12_-_108561157 Show fit	0.44	ENST00000228284.8 ENST00000431469.6 ENST00000546815.6	SART3 Links Ensembl NCBI GeneCards UniProt Show fit	spliceosome associated factor 3, U4/U6 recycling protein
chr2_+_216633411 Show fit	0.44	ENST00000233809.9	IGFBP2 Links Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 2
chr22_+_40177917 Show fit	0.44	ENST00000454349.7 ENST00000335727.13	TNRC6B Links Ensembl NCBI GeneCards UniProt Show fit	trinucleotide repeat containing adaptor 6B
chr5_-_149379286 Show fit	0.42	ENST00000261796.4	IL17B Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 17B
chr14_-_24634266 Show fit	0.40	ENST00000382540.5	GZMB Links Ensembl NCBI GeneCards UniProt Show fit	granzyme B
chr9_-_135961310 Show fit	0.40	ENST00000371756.4	UBAC1 Links Ensembl NCBI GeneCards UniProt Show fit	UBA domain containing 1
chr19_-_11197516 Show fit	0.34	ENST00000592903.5 ENST00000586659.6 ENST00000589359.5 ENST00000588724.5	KANK2 Links Ensembl NCBI GeneCards UniProt Show fit	KN motif and ankyrin repeat domains 2
chr13_-_103066411 Show fit	0.32	ENST00000245312.5	SLC10A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 10 member 2

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.0	29.9	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
7.6	30.3	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
5.5	16.4	GO:0002368	B cell cytokine production(GO:0002368)
3.6	17.9	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
2.9	8.7	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
2.9	17.2	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
2.5	7.4	GO:0006106	fumarate metabolic process(GO:0006106)
2.5	7.4	GO:0007518	myoblast fate determination(GO:0007518)
2.0	21.8	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
1.7	27.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
1.7	6.7	GO:1904045	cellular response to aldosterone(GO:1904045)
1.6	13.2	GO:0032262	pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
1.4	4.2	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
1.4	13.8	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
1.4	9.6	GO:0061198	fungiform papilla formation(GO:0061198)
1.3	3.9	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.3	15.3	GO:0051665	membrane raft localization(GO:0051665)
1.3	6.4	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
1.2	13.0	GO:0007144	female meiosis I(GO:0007144)
1.1	3.3	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.0	10.4	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
1.0	3.1	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
1.0	2.9	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.9	7.6	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.9	6.6	GO:0032218	riboflavin transport(GO:0032218)
0.9	4.7	GO:0006741	NADP biosynthetic process(GO:0006741)
0.9	4.3	GO:0030242	pexophagy(GO:0030242)
0.9	6.8	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.8	7.7	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.7	9.0	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.7	6.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.7	4.2	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.6	3.9	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.6	11.5	GO:0006105	succinate metabolic process(GO:0006105)
0.6	3.4	GO:0016554	cytidine to uridine editing(GO:0016554)
0.6	4.5	GO:0036444	mitochondrial protein processing(GO:0034982) calcium ion transmembrane import into mitochondrion(GO:0036444)
0.6	1.7	GO:2000417	negative regulation of eosinophil migration(GO:2000417)
0.6	4.4	GO:0015677	copper ion import(GO:0015677)
0.5	5.5	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.5	2.7	GO:0090131	mesenchyme migration(GO:0090131)
0.5	8.6	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.5	35.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.5	6.0	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4	3.9	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.4	6.8	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4	8.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.4	5.4	GO:0016576	histone dephosphorylation(GO:0016576)
0.4	9.9	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.3	3.4	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.3	4.6	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.3	7.8	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.3	1.0	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.3	2.8	GO:0002679	response to yeast(GO:0001878) respiratory burst involved in defense response(GO:0002679)
0.3	8.1	GO:1900745	activation of MAPKKK activity(GO:0000185) positive regulation of p38MAPK cascade(GO:1900745)
0.3	2.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3	6.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.2	5.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.2	1.9	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2	2.5	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.2	1.8	GO:0072553	terminal button organization(GO:0072553)
0.2	5.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.2	4.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.2	3.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.2	1.2	GO:0044351	macropinocytosis(GO:0044351)
0.2	0.7	GO:0070221	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2	6.7	GO:0001893	maternal placenta development(GO:0001893)
0.2	5.3	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.2	0.5	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2	3.0	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
0.1	5.8	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	9.7	GO:0043631	mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1	8.0	GO:0006458	'de novo' protein folding(GO:0006458)
0.1	1.4	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	3.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	1.4	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	0.9	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	0.3	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.1	20.2	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1	3.1	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.1	1.0	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	3.1	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.1	4.7	GO:0014003	oligodendrocyte development(GO:0014003)
0.1	1.5	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	1.2	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	0.7	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.1	1.0	GO:0006853	carnitine shuttle(GO:0006853)
0.1	0.5	GO:0070995	NADPH oxidation(GO:0070995)
0.1	2.0	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	2.6	GO:0006308	DNA catabolic process(GO:0006308)
0.1	3.1	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.7	GO:1903286	regulation of potassium ion import(GO:1903286)
0.1	3.0	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.1	0.8	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.5	GO:0060315	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0	2.0	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.9	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	6.0	GO:0006414	translational elongation(GO:0006414)
0.0	0.6	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.0	1.0	GO:0097435	fibril organization(GO:0097435)
0.0	6.2	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	0.4	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	4.4	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.0	1.1	GO:1901661	quinone metabolic process(GO:1901661)
0.0	2.0	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.4	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	2.2	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0060128	mesodermal cell migration(GO:0008078) corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.5	GO:0061436	establishment of skin barrier(GO:0061436)
0.0	0.5	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.4	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104) regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	3.2	GO:0006941	striated muscle contraction(GO:0006941)
0.0	0.0	GO:0003218	cardiac left ventricle formation(GO:0003218) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.2	GO:0008212	mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.6	27.9	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
3.3	3.3	GO:0070470	plasma membrane respiratory chain(GO:0070470)
2.9	11.5	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
2.7	35.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
2.0	13.8	GO:0031415	NatA complex(GO:0031415)
1.8	16.4	GO:0046696	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696)
1.6	9.9	GO:0032279	axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
1.5	4.5	GO:0005745	m-AAA complex(GO:0005745)
1.5	19.0	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.3	17.2	GO:0033093	Weibel-Palade body(GO:0033093)
1.0	2.9	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.9	9.3	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.9	30.0	GO:0016469	proton-transporting two-sector ATPase complex(GO:0016469)
0.9	10.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.8	5.8	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.8	5.4	GO:1990635	proximal dendrite(GO:1990635)
0.7	4.4	GO:0005927	muscle tendon junction(GO:0005927)
0.7	4.3	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.6	7.7	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.6	32.4	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5	6.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5	9.6	GO:0016580	Sin3 complex(GO:0016580)
0.4	4.6	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.3	4.0	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.3	3.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.3	10.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3	2.0	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.2	5.5	GO:0005721	pericentric heterochromatin(GO:0005721)
0.2	2.1	GO:0000938	GARP complex(GO:0000938)
0.2	5.4	GO:0001891	phagocytic cup(GO:0001891)
0.2	13.3	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2	1.6	GO:0033391	chromatoid body(GO:0033391)
0.2	0.5	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2	3.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.2	3.0	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.1	0.4	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	8.7	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	3.4	GO:0030056	hemidesmosome(GO:0030056)
0.1	7.8	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	2.3	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	1.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	0.5	GO:1990031	pinceau fiber(GO:1990031)
0.1	1.3	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	2.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	7.4	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.1	1.4	GO:0031089	platelet dense granule lumen(GO:0031089)
0.1	8.8	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	1.8	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	11.5	GO:0000922	spindle pole(GO:0000922)
0.1	4.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	8.9	GO:0005795	Golgi stack(GO:0005795)
0.1	2.0	GO:0035869	ciliary transition zone(GO:0035869)
0.1	1.6	GO:0005865	striated muscle thin filament(GO:0005865)
0.1	1.0	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	1.3	GO:0032982	myosin filament(GO:0032982)
0.0	4.2	GO:0043657	host(GO:0018995) host cell(GO:0043657)
0.0	8.3	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	8.0	GO:0005923	bicellular tight junction(GO:0005923)
0.0	3.1	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	7.8	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	2.0	GO:0043198	dendritic shaft(GO:0043198)
0.0	6.3	GO:0005840	ribosome(GO:0005840)
0.0	10.3	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	1.9	GO:0031594	neuromuscular junction(GO:0031594)
0.0	4.4	GO:0005770	late endosome(GO:0005770)
0.0	13.6	GO:0005635	nuclear envelope(GO:0005635)
0.0	2.0	GO:0043202	lysosomal lumen(GO:0043202)
0.0	9.3	GO:0000139	Golgi membrane(GO:0000139)
0.0	0.9	GO:0001772	immunological synapse(GO:0001772)
0.0	1.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.5	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	4.7	GO:0016607	nuclear speck(GO:0016607)
0.0	17.9	GO:0005783	endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.4	13.3	GO:0031753	endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
3.7	14.8	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
2.7	16.4	GO:0034186	apolipoprotein A-I binding(GO:0034186)
2.4	19.0	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.8	14.3	GO:0015288	porin activity(GO:0015288)
1.7	29.9	GO:0016018	cyclosporin A binding(GO:0016018)
1.6	6.4	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
1.5	27.9	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
1.3	3.9	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
1.2	6.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
1.0	13.8	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
1.0	7.7	GO:0034603	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.9	7.6	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.9	6.6	GO:0032217	riboflavin transporter activity(GO:0032217)
0.9	3.6	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.7	8.7	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.7	4.9	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.7	6.8	GO:0070569	uridylyltransferase activity(GO:0070569)
0.7	17.2	GO:0031489	myosin V binding(GO:0031489)
0.6	3.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.6	9.6	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.6	6.7	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.5	24.6	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.5	14.1	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5	8.6	GO:0031996	thioesterase binding(GO:0031996)
0.5	9.9	GO:0050811	GABA receptor binding(GO:0050811)
0.4	4.3	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.4	4.4	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.4	10.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4	1.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.3	1.4	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3	6.3	GO:0017070	U6 snRNA binding(GO:0017070)
0.3	31.5	GO:0009055	electron carrier activity(GO:0009055)
0.3	6.7	GO:0035613	RNA stem-loop binding(GO:0035613)
0.3	1.0	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.3	6.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.3	3.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3	3.1	GO:0034485	inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.3	6.0	GO:0003746	translation elongation factor activity(GO:0003746)
0.3	2.0	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.3	0.8	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.2	1.2	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.2	5.5	GO:0035173	histone kinase activity(GO:0035173)
0.2	0.7	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.2	13.2	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.2	5.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.2	1.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.2	7.8	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2	0.5	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.2	2.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.2	1.7	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.2	0.5	GO:0004040	amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.2	6.0	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.2	4.7	GO:0003951	NAD+ kinase activity(GO:0003951)
0.2	1.6	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	4.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	1.0	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1	20.6	GO:0047485	protein N-terminus binding(GO:0047485)
0.1	1.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1	5.1	GO:0016831	carboxy-lyase activity(GO:0016831)
0.1	3.4	GO:0030506	ankyrin binding(GO:0030506)
0.1	7.4	GO:0016836	hydro-lyase activity(GO:0016836)
0.1	11.7	GO:0051087	chaperone binding(GO:0051087)
0.1	1.0	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	13.0	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	0.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	5.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	1.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1	7.2	GO:0030295	protein kinase activator activity(GO:0030295)
0.1	0.2	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.1	2.1	GO:0042056	chemoattractant activity(GO:0042056)
0.1	2.8	GO:0004601	peroxidase activity(GO:0004601)
0.1	1.8	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	10.4	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	2.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	3.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	3.9	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	2.7	GO:0017022	myosin binding(GO:0017022)
0.0	5.0	GO:0032947	protein complex scaffold(GO:0032947)
0.0	1.3	GO:0000146	microfilament motor activity(GO:0000146)
0.0	4.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	2.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.6	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	1.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	3.0	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	5.8	GO:0003924	GTPase activity(GO:0003924)
0.0	0.5	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	1.4	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.0	1.8	GO:0005178	integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	13.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5	16.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.4	9.6	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	29.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.3	21.4	PID FOXO PATHWAY	FoxO family signaling
0.2	9.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	19.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	8.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	7.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	3.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	2.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	5.4	PID INSULIN PATHWAY	Insulin Pathway
0.1	4.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	6.0	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	5.5	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	2.2	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.1	1.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	2.2	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.9	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	2.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	1.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	1.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	87.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
1.2	25.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.9	13.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.6	14.4	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.5	7.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5	36.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.4	13.0	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4	10.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.4	6.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4	9.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.3	5.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.3	7.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.3	9.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	6.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	7.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	5.8	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2	3.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.2	10.3	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1	13.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	3.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	3.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	3.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	1.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	9.2	REACTOME TRANSLATION	Genes involved in Translation
0.1	2.9	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	14.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.1	3.1	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	2.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	3.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	3.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.4	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	1.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	4.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	3.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.9	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.9	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors