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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR4A2

Z-value: 5.25

Motif logo

Transcription factors associated with NR4A2

Gene Symbol Gene ID Gene Info
ENSG00000153234.15 NR4A2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A2hg38_v1_chr2_-_156342348_156342466-0.282.0e-05Click!

Activity profile of NR4A2 motif

Sorted Z-values of NR4A2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_144095054 30.34 ENST00000318911.5
cytochrome c1
chr2_-_175181663 18.41 ENST00000392541.3
ENST00000284727.9
ENST00000409194.5
ATP synthase membrane subunit c locus 3
chr10_+_79347491 17.43 ENST00000448165.1
peptidylprolyl isomerase F
chr11_-_64246907 13.83 ENST00000309318.8
protein phosphatase 1 regulatory inhibitor subunit 14B
chr11_-_64246190 13.04 ENST00000392210.6
protein phosphatase 1 regulatory inhibitor subunit 14B
chr20_+_3796288 13.01 ENST00000439880.6
ENST00000245960.10
cell division cycle 25B
chr7_+_128758947 12.59 ENST00000493278.1
calumenin
chr10_+_79347460 12.44 ENST00000225174.8
peptidylprolyl isomerase F
chr5_-_134004635 12.31 ENST00000425992.2
ENST00000395044.7
ENST00000395047.6
voltage dependent anion channel 1
chr1_-_17054015 11.51 ENST00000375499.8
succinate dehydrogenase complex iron sulfur subunit B
chr21_+_41168142 11.50 ENST00000330333.11
beta-secretase 2
chr3_-_167734465 10.69 ENST00000487947.6
programmed cell death 10
chr2_-_206159509 10.55 ENST00000423725.5
NADH:ubiquinone oxidoreductase core subunit S1
chr17_+_81703356 10.44 ENST00000333676.8
ENST00000571730.1
mitochondrial ribosomal protein L12
novel protein
chr21_+_41167774 10.35 ENST00000328735.10
ENST00000347667.5
beta-secretase 2
chr20_-_62143374 10.28 ENST00000370873.9
ENST00000370858.3
proteasome 20S subunit alpha 7
chr19_-_10335773 9.87 ENST00000592439.1
intercellular adhesion molecule 3
chr4_-_70839343 9.73 ENST00000514161.5
ENST00000499044.6
G-rich RNA sequence binding factor 1
chr1_+_32292067 9.58 ENST00000373548.8
ENST00000428704.1
histone deacetylase 1
chrX_-_110440218 9.56 ENST00000372057.1
ENST00000372054.3
AMMECR nuclear protein 1
G protein subunit gamma 5 pseudogene 2
chr2_-_206159410 9.31 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NADH:ubiquinone oxidoreductase core subunit S1
chr15_-_55270280 9.31 ENST00000564609.5
RAB27A, member RAS oncogene family
chr8_-_130016414 9.28 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYFIP related Rac1 interactor B
chr7_+_39623547 9.16 ENST00000005257.7
RAS like proto-oncogene A
chr13_+_30427950 8.84 ENST00000436446.1
ubiquitin conjugating enzyme E2 L5
chr2_-_197499826 8.76 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
heat shock protein family D (Hsp60) member 1
chr2_+_85577540 8.70 ENST00000263864.10
ENST00000409760.1
vesicle associated membrane protein 8
chr8_-_130016622 8.66 ENST00000518283.5
ENST00000519110.5
CYFIP related Rac1 interactor B
chr1_+_67685342 8.12 ENST00000617962.2
growth arrest and DNA damage inducible alpha
chr2_-_206159194 8.01 ENST00000455934.6
ENST00000449699.5
ENST00000454195.1
NADH:ubiquinone oxidoreductase core subunit S1
chr17_+_54900824 7.98 ENST00000572405.5
ENST00000572158.5
ENST00000575882.6
ENST00000572298.5
ENST00000536554.5
ENST00000575333.5
ENST00000570499.5
ENST00000572576.5
target of myb1 like 1 membrane trafficking protein
chr15_-_55270383 7.92 ENST00000396307.6
RAB27A, member RAS oncogene family
chr2_+_27212866 7.78 ENST00000419744.1
all-trans retinoic acid induced differentiation factor
chr11_+_34916611 7.67 ENST00000227868.9
ENST00000430469.6
ENST00000533262.1
pyruvate dehydrogenase complex component X
chr2_-_197499857 7.65 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
heat shock protein family D (Hsp60) member 1
chr10_+_49942048 7.46 ENST00000651259.3
ENST00000652716.1
translocase of inner mitochondrial membrane 23 homolog B
chr8_-_130016395 7.44 ENST00000523509.5
CYFIP related Rac1 interactor B
chr2_+_197500398 7.40 ENST00000604458.1
HSPE1-MOB4 readthrough
chr1_-_241519701 7.40 ENST00000366560.4
ENST00000683521.1
fumarate hydratase
chr3_-_113746218 7.25 ENST00000497255.1
ENST00000240922.8
ENST00000478020.1
ENST00000493900.5
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr3_-_167734510 7.23 ENST00000475915.6
ENST00000462725.6
ENST00000461494.5
programmed cell death 10
chr7_+_48089257 7.22 ENST00000436673.5
ENST00000395564.9
uridine phosphorylase 1
chr1_+_155613221 7.19 ENST00000462250.2
misato mitochondrial distribution and morphology regulator 1
chr9_-_146140 7.02 ENST00000475990.5
COBW domain containing 1
chr1_+_155209213 6.92 ENST00000609421.1
metaxin 1
chr16_-_69334871 6.90 ENST00000562949.1
novel protein, COG8-PDF readthrough
chr1_+_162561504 6.83 ENST00000271469.7
ENST00000367926.8
UDP-N-acetylglucosamine pyrophosphorylase 1
chr10_+_45972482 6.81 ENST00000580018.4
translocase of inner mitochondrial membrane 23
chrX_-_130165699 6.71 ENST00000676328.1
ENST00000675857.1
ENST00000675427.1
ENST00000675092.1
apoptosis inducing factor mitochondria associated 1
chr4_-_102345469 6.63 ENST00000356736.5
ENST00000682932.1
solute carrier family 39 member 8
chr3_-_113746185 6.57 ENST00000616174.1
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr8_+_144358974 6.57 ENST00000526891.2
solute carrier family 52 member 2
chr4_-_73223082 6.36 ENST00000509867.6
ankyrin repeat domain 17
chr10_+_14838288 6.35 ENST00000640019.3
ENST00000493178.1
ENST00000378372.8
novel protein
heat shock protein family A (Hsp70) member 14
chr9_-_128127711 6.01 ENST00000449878.1
ENST00000338961.11
ENST00000678174.1
prostaglandin E synthase 2
chr19_-_7943648 5.97 ENST00000597926.1
ENST00000270538.8
translocase of inner mitochondrial membrane 44
chr7_+_48088596 5.95 ENST00000416681.5
ENST00000331803.8
ENST00000432131.5
uridine phosphorylase 1
chr19_-_2328573 5.82 ENST00000587502.2
ENST00000252622.15
ENST00000585409.2
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr2_+_197500371 5.77 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr17_+_28744034 5.53 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr14_-_103921494 5.52 ENST00000557040.5
ENST00000414262.6
ENST00000555030.5
ENST00000554713.2
ENST00000286953.8
ENST00000553430.5
ATP synthase membrane subunit j
chr7_-_73522278 5.45 ENST00000404251.1
ENST00000339594.9
bromodomain adjacent to zinc finger domain 1B
chr19_+_46347063 5.42 ENST00000012443.9
ENST00000391919.1
protein phosphatase 5 catalytic subunit
chr19_+_6739650 5.38 ENST00000313285.12
ENST00000313244.14
ENST00000596758.5
thyroid hormone receptor interactor 10
chr20_+_48921701 5.31 ENST00000371917.5
ADP ribosylation factor guanine nucleotide exchange factor 2
chr15_-_42491105 5.18 ENST00000565380.5
ENST00000564754.7
zinc finger protein 106
chr3_+_138621225 5.16 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr15_+_75043263 5.07 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr22_+_29767351 4.90 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr1_+_201955496 4.77 ENST00000367287.5
translocase of inner mitochondrial membrane 17A
chr7_+_112423137 4.77 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chr4_+_80197493 4.74 ENST00000415738.3
PR/SET domain 8
chr1_-_1779976 4.67 ENST00000378625.5
NAD kinase
chr4_-_151015713 4.56 ENST00000357115.9
LPS responsive beige-like anchor protein
chr20_+_48921775 4.55 ENST00000681021.1
ENST00000679436.1
ADP ribosylation factor guanine nucleotide exchange factor 2
chr18_-_12377200 4.54 ENST00000269143.8
AFG3 like matrix AAA peptidase subunit 2
chr4_-_110198650 4.46 ENST00000394607.7
ELOVL fatty acid elongase 6
chr8_-_52714414 4.32 ENST00000435644.6
ENST00000518710.5
ENST00000025008.10
ENST00000517963.1
RB1 inducible coiled-coil 1
chr16_+_56730099 4.22 ENST00000563858.5
ENST00000566315.5
ENST00000308159.10
ENST00000569842.5
ENST00000569863.5
nucleoporin 93
chr7_+_39623886 4.09 ENST00000436179.1
RAS like proto-oncogene A
chr10_+_22316445 4.07 ENST00000448361.5
COMM domain containing 3
chr2_+_233712905 3.98 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr19_+_1407517 3.95 ENST00000336761.10
ENST00000233078.9
ENST00000592522.5
DAZ associated protein 1
chr5_-_138575359 3.90 ENST00000297185.9
ENST00000678300.1
ENST00000677425.1
ENST00000677064.1
ENST00000507115.6
heat shock protein family A (Hsp70) member 9
chr2_+_227813834 3.89 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr4_+_41612702 3.73 ENST00000509277.5
LIM and calponin homology domains 1
chr3_+_138621207 3.69 ENST00000464668.5
Fas apoptotic inhibitory molecule
chr15_+_78149354 3.58 ENST00000558554.5
ENST00000557826.5
ENST00000561279.5
ENST00000299518.7
ENST00000559186.5
ENST00000560770.5
ENST00000559881.5
ENST00000559205.1
ENST00000629769.2
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
chr3_+_179604785 3.54 ENST00000611971.4
ENST00000493866.5
ENST00000259037.8
ENST00000472629.5
ENST00000482604.5
NADH:ubiquinone oxidoreductase subunit B5
chr10_+_22316375 3.50 ENST00000376836.8
ENST00000456711.5
ENST00000444869.5
ENST00000475460.6
ENST00000602390.5
ENST00000489125.2
COMM domain containing 3
COMMD3-BMI1 readthrough
chr2_-_26244597 3.48 ENST00000492433.2
ENST00000645274.1
ENST00000380649.8
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
chr9_+_113221528 3.46 ENST00000374212.5
solute carrier family 31 member 1
chr4_-_40515967 3.41 ENST00000381795.10
RNA binding motif protein 47
chr16_+_4624811 3.41 ENST00000415496.5
ENST00000262370.12
ENST00000587747.5
ENST00000399577.9
ENST00000588994.5
ENST00000586183.5
mahogunin ring finger 1
chr8_-_143944737 3.36 ENST00000398774.6
plectin
chr5_+_218241 3.29 ENST00000617470.4
ENST00000504309.5
ENST00000510361.5
ENST00000264932.11
succinate dehydrogenase complex flavoprotein subunit A
chr4_-_151015263 3.17 ENST00000510413.5
ENST00000507224.5
ENST00000651943.2
LPS responsive beige-like anchor protein
chr1_-_20661356 3.14 ENST00000602624.7
ENST00000464364.1
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr4_-_110198579 3.14 ENST00000302274.8
ELOVL fatty acid elongase 6
chr14_+_23322019 3.11 ENST00000557702.5
poly(A) binding protein nuclear 1
chr2_+_206159580 3.11 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
eukaryotic translation elongation factor 1 beta 2
chr4_-_138242325 3.09 ENST00000280612.9
solute carrier family 7 member 11
chr22_+_31122923 3.09 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
inositol polyphosphate-5-phosphatase J
chr2_+_108621260 3.07 ENST00000409441.5
LIM zinc finger domain containing 1
chr17_+_28744002 3.03 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TNF receptor associated factor 4
chr20_+_62143729 3.02 ENST00000331758.8
ENST00000450482.5
SS18L1 subunit of BAF chromatin remodeling complex
chr2_+_26244731 2.97 ENST00000537713.5
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr16_+_85908988 2.95 ENST00000566369.1
interferon regulatory factor 8
chr2_+_206159884 2.94 ENST00000392222.7
eukaryotic translation elongation factor 1 beta 2
chr1_+_212565334 2.86 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr17_-_58280928 2.83 ENST00000225275.4
myeloperoxidase
chr7_-_92246045 2.81 ENST00000394507.5
ENST00000458177.6
ENST00000340022.6
ENST00000444960.5
KRIT1 ankyrin repeat containing
chr19_+_1407653 2.73 ENST00000587079.5
DAZ associated protein 1
chr1_-_229434086 2.68 ENST00000366684.7
ENST00000684723.1
ENST00000366683.4
actin alpha 1, skeletal muscle
chr12_-_55728977 2.67 ENST00000552164.5
CD63 molecule
chr5_-_150449731 2.60 ENST00000407193.7
ribosomal protein S14
chr7_+_112450451 2.59 ENST00000429071.5
ENST00000403825.8
ENST00000675268.1
interferon related developmental regulator 1
novel protein
chr20_+_19758245 2.52 ENST00000255006.12
Ras and Rab interactor 2
chrX_-_21758021 2.52 ENST00000646008.1
small muscle protein X-linked
chr2_-_64019367 2.50 ENST00000272322.9
VPS54 subunit of GARP complex
chr7_-_92245795 2.49 ENST00000412043.6
ENST00000430102.5
ENST00000425073.1
ENST00000394505.7
ENST00000394503.6
ENST00000454017.5
ENST00000440209.5
ENST00000413688.5
ENST00000452773.5
ENST00000433016.5
ENST00000422347.5
ENST00000458493.5
ENST00000425919.5
ENST00000650585.1
KRIT1 ankyrin repeat containing
novel protein
chr11_+_68030896 2.45 ENST00000525628.1
NADH:ubiquinone oxidoreductase core subunit S8
chr16_-_30526518 2.44 ENST00000380412.7
zinc finger protein 768
chr9_-_93453540 2.43 ENST00000375412.11
family with sequence similarity 120A opposite strand
chr3_-_45958572 2.32 ENST00000433878.5
FYVE and coiled-coil domain autophagy adaptor 1
chr9_+_110668854 2.30 ENST00000189978.10
ENST00000374440.7
muscle associated receptor tyrosine kinase
chr8_-_99893697 2.26 ENST00000518171.5
ENST00000520468.7
cytochrome c oxidase subunit 6C
chr16_+_28931942 2.22 ENST00000324662.8
ENST00000538922.8
CD19 molecule
chr2_-_110115811 2.09 ENST00000272462.3
mal, T cell differentiation protein like
chr2_+_233718734 2.05 ENST00000373409.8
UDP glucuronosyltransferase family 1 member A4
chr19_+_44891206 2.01 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
translocase of outer mitochondrial membrane 40
chrX_-_133415478 1.99 ENST00000370828.4
glypican 4
chr17_-_81194028 1.96 ENST00000570817.5
centrosomal protein 131
chr20_-_35411963 1.93 ENST00000349714.9
ENST00000438533.5
ENST00000359226.6
ENST00000374384.6
ENST00000374385.10
ENST00000424405.5
ENST00000397554.5
ENST00000374380.6
ubiquinol-cytochrome c reductase complex assembly factor 1
chr12_-_55728994 1.92 ENST00000257857.9
CD63 molecule
chr12_-_56645955 1.89 ENST00000552959.5
ENST00000551020.5
ENST00000553007.2
ENST00000262030.8
ATP synthase F1 subunit beta
chr14_+_22494810 1.85 ENST00000390493.1
T cell receptor alpha joining 44
chrX_-_21758097 1.85 ENST00000379494.4
small muscle protein X-linked
chr22_-_42090743 1.82 ENST00000498737.8
ENST00000617763.1
NADH:ubiquinone oxidoreductase subunit A6
chr12_-_6606320 1.78 ENST00000642594.1
ENST00000644289.1
ENST00000645095.1
chromodomain helicase DNA binding protein 4
chr5_-_150449676 1.68 ENST00000312037.6
ribosomal protein S14
chr11_-_9314564 1.68 ENST00000611268.4
ENST00000528080.6
ENST00000527813.5
ENST00000533723.1
transmembrane protein 41B
chr18_+_61333424 1.68 ENST00000262717.9
cadherin 20
chr5_+_40679907 1.67 ENST00000302472.4
prostaglandin E receptor 4
chr4_-_98929092 1.58 ENST00000280892.10
ENST00000511644.5
ENST00000504432.5
ENST00000450253.7
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr9_+_110668779 1.56 ENST00000416899.7
ENST00000374448.9
muscle associated receptor tyrosine kinase
chr13_+_32586443 1.52 ENST00000315596.15
PDS5 cohesin associated factor B
chr7_-_151080833 1.51 ENST00000353841.6
ENST00000482571.2
Fas activated serine/threonine kinase
chr3_-_52826834 1.45 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain 4
chr7_-_151080787 1.42 ENST00000540185.5
ENST00000297532.11
Fas activated serine/threonine kinase
chr11_+_122838492 1.42 ENST00000227348.9
cytotoxic and regulatory T cell molecule
chrX_-_154412083 1.42 ENST00000451865.5
ENST00000432135.1
ENST00000369809.5
ENST00000393638.5
ENST00000424626.5
ENST00000309585.9
deoxyribonuclease 1 like 1
chr22_-_37484505 1.38 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_-_2711633 1.37 ENST00000435359.5
clustered mitochondria homolog
chr1_-_154192058 1.31 ENST00000271850.11
ENST00000368530.7
ENST00000651641.1
tropomyosin 3
chr17_-_10373002 1.29 ENST00000252172.9
ENST00000418404.8
myosin heavy chain 13
chr17_-_2711736 1.28 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
clustered mitochondria homolog
chr6_+_139135063 1.23 ENST00000367658.3
hdc homolog, cell cycle regulator
chr19_-_3062464 1.21 ENST00000327141.9
TLE family member 5, transcriptional modulator
chr19_-_49049111 1.20 ENST00000448456.4
chorionic gonadotropin subunit beta 8
chr1_+_206684887 1.20 ENST00000367103.4
ENST00000294981.8
MAPK activated protein kinase 2
chr16_+_3654683 1.20 ENST00000246949.10
deoxyribonuclease 1
chr8_-_18083278 1.13 ENST00000636691.1
N-acylsphingosine amidohydrolase 1
chr7_-_81770039 1.10 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
hepatocyte growth factor
chr1_+_103571077 1.07 ENST00000610648.1
amylase alpha 2B
chr21_-_33641721 1.07 ENST00000399442.1
ENST00000413017.2
ENST00000445393.5
ENST00000417979.5
ENST00000381554.8
ENST00000426935.5
ENST00000381540.7
ENST00000361534.6
crystallin zeta like 1
chr7_-_151736304 1.03 ENST00000492843.6
protein kinase AMP-activated non-catalytic subunit gamma 2
chr13_-_52011337 0.96 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATPase copper transporting beta
chr5_+_177600104 0.96 ENST00000029410.10
ENST00000510761.1
ENST00000505468.1
beta-1,4-galactosyltransferase 7
chr22_-_30564889 0.95 ENST00000401975.5
ENST00000428682.5
ENST00000423299.5
galactose-3-O-sulfotransferase 1
chr11_+_45805108 0.95 ENST00000530471.1
ENST00000314134.4
solute carrier family 35 member C1
chr7_-_81770122 0.95 ENST00000423064.7
hepatocyte growth factor
chrX_-_63785510 0.89 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr3_-_151316795 0.87 ENST00000260843.5
G protein-coupled receptor 87
chr19_-_35563653 0.83 ENST00000262623.4
ATPase H+/K+ transporting subunit alpha
chr11_-_64744102 0.83 ENST00000431822.5
ENST00000394432.8
ENST00000377486.7
RAS guanyl releasing protein 2
chr20_-_37527862 0.75 ENST00000373537.7
ENST00000445723.5
ENST00000414080.1
BLCAP apoptosis inducing factor
chr3_-_197298558 0.68 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
discs large MAGUK scaffold protein 1
chr17_+_81712236 0.68 ENST00000545862.5
ENST00000350690.10
ENST00000331531.9
solute carrier family 25 member 10
chrX_-_155071064 0.66 ENST00000369484.8
ENST00000369476.8
C-X9-C motif containing 4
mature T cell proliferation 1
chr11_-_66371728 0.59 ENST00000357440.7
ENST00000619145.4
solute carrier family 29 member 2
chrX_+_106802660 0.56 ENST00000357242.10
ENST00000310452.6
ENST00000481617.6
ENST00000276175.7
TBC1 domain family member 8B
chr19_-_15125095 0.55 ENST00000600984.5
ilvB acetolactate synthase like
chr1_-_115768702 0.55 ENST00000261448.6
calsequestrin 2
chr8_-_99893135 0.54 ENST00000524245.5
cytochrome c oxidase subunit 6C
chr8_-_99893622 0.54 ENST00000520271.5
ENST00000522940.5
ENST00000523016.1
ENST00000517682.6
ENST00000297564.6
cytochrome c oxidase subunit 6C
chr7_+_2403567 0.53 ENST00000258711.7
ENST00000618655.2
carbohydrate sulfotransferase 12
chr1_+_6034980 0.52 ENST00000378092.6
ENST00000472700.7
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr14_-_24634160 0.52 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr7_+_73830988 0.52 ENST00000340958.4
claudin 4
chr6_+_106629560 0.49 ENST00000369046.8
glutaminyl-tRNA amidotransferase subunit QRSL1
chr3_+_159852933 0.46 ENST00000482804.1
schwannomin interacting protein 1
chr12_-_108561157 0.44 ENST00000228284.8
ENST00000431469.6
ENST00000546815.6
spliceosome associated factor 3, U4/U6 recycling protein
chr2_+_216633411 0.44 ENST00000233809.9
insulin like growth factor binding protein 2
chr22_+_40177917 0.44 ENST00000454349.7
ENST00000335727.13
trinucleotide repeat containing adaptor 6B
chr5_-_149379286 0.42 ENST00000261796.4
interleukin 17B
chr14_-_24634266 0.40 ENST00000382540.5
granzyme B
chr9_-_135961310 0.40 ENST00000371756.4
UBA domain containing 1
chr19_-_11197516 0.34 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KN motif and ankyrin repeat domains 2
chr13_-_103066411 0.32 ENST00000245312.5
solute carrier family 10 member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.0 29.9 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
7.6 30.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
5.5 16.4 GO:0002368 B cell cytokine production(GO:0002368)
3.6 17.9 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
2.9 8.7 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
2.9 17.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
2.5 7.4 GO:0006106 fumarate metabolic process(GO:0006106)
2.5 7.4 GO:0007518 myoblast fate determination(GO:0007518)
2.0 21.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
1.7 27.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
1.7 6.7 GO:1904045 cellular response to aldosterone(GO:1904045)
1.6 13.2 GO:0032262 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
1.4 4.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
1.4 13.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
1.4 9.6 GO:0061198 fungiform papilla formation(GO:0061198)
1.3 3.9 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.3 15.3 GO:0051665 membrane raft localization(GO:0051665)
1.3 6.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.2 13.0 GO:0007144 female meiosis I(GO:0007144)
1.1 3.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.0 10.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
1.0 3.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
1.0 2.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.9 7.6 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.9 6.6 GO:0032218 riboflavin transport(GO:0032218)
0.9 4.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.9 4.3 GO:0030242 pexophagy(GO:0030242)
0.9 6.8 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.8 7.7 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.7 9.0 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.7 6.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.7 4.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.6 3.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.6 11.5 GO:0006105 succinate metabolic process(GO:0006105)
0.6 3.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.6 4.5 GO:0036444 mitochondrial protein processing(GO:0034982) calcium ion transmembrane import into mitochondrion(GO:0036444)
0.6 1.7 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.6 4.4 GO:0015677 copper ion import(GO:0015677)
0.5 5.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.5 2.7 GO:0090131 mesenchyme migration(GO:0090131)
0.5 8.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.5 35.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.5 6.0 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 3.9 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.4 6.8 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4 8.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.4 5.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 9.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 3.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.3 4.6 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.3 7.8 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.3 1.0 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.3 2.8 GO:0002679 response to yeast(GO:0001878) respiratory burst involved in defense response(GO:0002679)
0.3 8.1 GO:1900745 activation of MAPKKK activity(GO:0000185) positive regulation of p38MAPK cascade(GO:1900745)
0.3 2.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3 6.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 5.0 GO:0048311 mitochondrion distribution(GO:0048311)
0.2 1.9 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 2.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 1.8 GO:0072553 terminal button organization(GO:0072553)
0.2 5.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 4.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 3.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.2 1.2 GO:0044351 macropinocytosis(GO:0044351)
0.2 0.7 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2 6.7 GO:0001893 maternal placenta development(GO:0001893)
0.2 5.3 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 0.5 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2 3.0 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 5.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 9.7 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 8.0 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 1.4 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 3.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.9 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 20.2 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1 3.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 1.0 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 3.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 4.7 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 1.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 1.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 1.0 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.5 GO:0070995 NADPH oxidation(GO:0070995)
0.1 2.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 2.6 GO:0006308 DNA catabolic process(GO:0006308)
0.1 3.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.7 GO:1903286 regulation of potassium ion import(GO:1903286)
0.1 3.0 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.1 0.8 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.5 GO:0060315 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 2.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 6.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.6 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 1.0 GO:0097435 fibril organization(GO:0097435)
0.0 6.2 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 4.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.1 GO:1901661 quinone metabolic process(GO:1901661)
0.0 2.0 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 2.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0060128 mesodermal cell migration(GO:0008078) corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.4 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104) regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 3.2 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.0 GO:0003218 cardiac left ventricle formation(GO:0003218) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 27.9 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
3.3 3.3 GO:0070470 plasma membrane respiratory chain(GO:0070470)
2.9 11.5 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
2.7 35.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
2.0 13.8 GO:0031415 NatA complex(GO:0031415)
1.8 16.4 GO:0046696 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696)
1.6 9.9 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
1.5 4.5 GO:0005745 m-AAA complex(GO:0005745)
1.5 19.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.3 17.2 GO:0033093 Weibel-Palade body(GO:0033093)
1.0 2.9 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.9 9.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.9 30.0 GO:0016469 proton-transporting two-sector ATPase complex(GO:0016469)
0.9 10.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.8 5.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.8 5.4 GO:1990635 proximal dendrite(GO:1990635)
0.7 4.4 GO:0005927 muscle tendon junction(GO:0005927)
0.7 4.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.6 7.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.6 32.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5 6.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5 9.6 GO:0016580 Sin3 complex(GO:0016580)
0.4 4.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.3 4.0 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.3 3.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 10.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 2.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 5.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 2.1 GO:0000938 GARP complex(GO:0000938)
0.2 5.4 GO:0001891 phagocytic cup(GO:0001891)
0.2 13.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 1.6 GO:0033391 chromatoid body(GO:0033391)
0.2 0.5 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 3.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 3.0 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 0.4 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 8.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 3.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 7.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.5 GO:1990031 pinceau fiber(GO:1990031)
0.1 1.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 2.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 7.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 8.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 11.5 GO:0000922 spindle pole(GO:0000922)
0.1 4.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 8.9 GO:0005795 Golgi stack(GO:0005795)
0.1 2.0 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.3 GO:0032982 myosin filament(GO:0032982)
0.0 4.2 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 8.3 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 8.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 7.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 6.3 GO:0005840 ribosome(GO:0005840)
0.0 10.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.4 GO:0005770 late endosome(GO:0005770)
0.0 13.6 GO:0005635 nuclear envelope(GO:0005635)
0.0 2.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 9.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 4.7 GO:0016607 nuclear speck(GO:0016607)
0.0 17.9 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.3 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
3.7 14.8 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
2.7 16.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
2.4 19.0 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.8 14.3 GO:0015288 porin activity(GO:0015288)
1.7 29.9 GO:0016018 cyclosporin A binding(GO:0016018)
1.6 6.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
1.5 27.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.3 3.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.2 6.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
1.0 13.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
1.0 7.7 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.9 7.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.9 6.6 GO:0032217 riboflavin transporter activity(GO:0032217)
0.9 3.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.7 8.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.7 4.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.7 6.8 GO:0070569 uridylyltransferase activity(GO:0070569)
0.7 17.2 GO:0031489 myosin V binding(GO:0031489)
0.6 3.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.6 9.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.6 6.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.5 24.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.5 14.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5 8.6 GO:0031996 thioesterase binding(GO:0031996)
0.5 9.9 GO:0050811 GABA receptor binding(GO:0050811)
0.4 4.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.4 4.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.4 10.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 1.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.3 1.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 6.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 31.5 GO:0009055 electron carrier activity(GO:0009055)
0.3 6.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.3 1.0 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.3 6.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 3.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 3.1 GO:0034485 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.3 6.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 2.0 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.3 0.8 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.2 1.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 5.5 GO:0035173 histone kinase activity(GO:0035173)
0.2 0.7 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 13.2 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.2 5.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 7.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 2.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 0.5 GO:0004040 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.2 6.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 4.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.2 1.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 4.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.0 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 20.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 1.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 5.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 3.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 7.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 11.7 GO:0051087 chaperone binding(GO:0051087)
0.1 1.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 13.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 5.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 7.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 2.1 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.8 GO:0004601 peroxidase activity(GO:0004601)
0.1 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 10.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 3.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 3.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 2.7 GO:0017022 myosin binding(GO:0017022)
0.0 5.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 4.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 3.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 5.8 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.4 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 1.8 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 13.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5 16.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 9.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 29.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 21.4 PID FOXO PATHWAY FoxO family signaling
0.2 9.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 19.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 8.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 7.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 3.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.8 PID IL23 PATHWAY IL23-mediated signaling events
0.1 5.4 PID INSULIN PATHWAY Insulin Pathway
0.1 4.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 6.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.5 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.2 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 1.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 87.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.2 25.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.9 13.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.6 14.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.5 7.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 36.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.4 13.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 10.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.4 6.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 9.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.3 5.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 7.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 9.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 6.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 7.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 5.8 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2 3.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.2 10.3 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 13.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 9.2 REACTOME TRANSLATION Genes involved in Translation
0.1 2.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 14.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 3.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 4.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 3.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors