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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR5A2

Z-value: 7.04

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Transcription factors associated with NR5A2

Gene Symbol Gene ID Gene Info
ENSG00000116833.14 NR5A2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR5A2hg38_v1_chr1_+_200027702_2000277160.421.0e-10Click!

Activity profile of NR5A2 motif

Sorted Z-values of NR5A2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR5A2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_21023318 93.79 ENST00000298684.9
ENST00000557169.5
ENST00000553563.5
NDRG family member 2
chr14_-_21024092 80.66 ENST00000554398.5
NDRG family member 2
chr14_-_21023954 79.06 ENST00000554094.5
NDRG family member 2
chr16_+_176659 56.39 ENST00000320868.9
ENST00000397797.1
hemoglobin subunit alpha 1
chr8_-_109691766 49.97 ENST00000529190.5
ENST00000422135.5
syntabulin
chrX_-_47574738 48.11 ENST00000640721.1
synapsin I
chr2_+_219627394 39.00 ENST00000373760.6
solute carrier family 4 member 3
chr14_-_21022817 38.99 ENST00000554104.5
NDRG family member 2
chr16_+_56589521 37.29 ENST00000200691.5
ENST00000570176.1
metallothionein 3
chr8_+_22053543 34.79 ENST00000519850.5
ENST00000381470.7
dematin actin binding protein
chr14_-_103522696 34.44 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
creatine kinase B
chrX_+_103776831 33.08 ENST00000621218.5
ENST00000619236.1
proteolipid protein 1
chrX_+_103776493 32.53 ENST00000433491.5
ENST00000612423.4
ENST00000443502.5
proteolipid protein 1
chr17_-_44911281 32.03 ENST00000638304.1
ENST00000591880.2
ENST00000586125.2
ENST00000639921.1
glial fibrillary acidic protein
chr3_+_133746385 31.69 ENST00000482271.5
ENST00000402696.9
transferrin
chr19_-_36152427 29.84 ENST00000589154.1
ENST00000292907.8
cytochrome c oxidase subunit 7A1
chrX_-_49200174 27.80 ENST00000472598.5
ENST00000263233.9
ENST00000479808.5
synaptophysin
chr14_-_21023144 27.78 ENST00000554531.5
NDRG family member 2
chr11_-_111910790 27.08 ENST00000533280.6
crystallin alpha B
chr5_-_176629943 26.88 ENST00000510387.5
ENST00000506696.1
synuclein beta
chr22_-_38844020 26.15 ENST00000333039.4
neuronal pentraxin receptor
chr11_-_111910830 26.09 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr1_-_149917826 24.58 ENST00000369145.1
ENST00000369146.8
synaptic vesicle glycoprotein 2A
chr6_-_34392627 24.33 ENST00000607016.2
nudix hydrolase 3
chr17_-_8162932 23.96 ENST00000488857.5
ENST00000316509.11
ENST00000481878.1
ENST00000498285.1
vesicle associated membrane protein 2
novel protein
chr1_+_19596960 23.53 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chr9_-_119369416 22.89 ENST00000373964.2
ENST00000265922.8
BMP/retinoic acid inducible neural specific 1
chr1_-_241357225 22.49 ENST00000366565.5
regulator of G protein signaling 7
chr16_+_7303245 21.79 ENST00000674626.1
RNA binding fox-1 homolog 1
chr8_-_109691590 21.15 ENST00000532779.5
ENST00000534578.5
syntabulin
chr20_-_63499074 20.99 ENST00000217182.6
ENST00000642899.1
eukaryotic translation elongation factor 1 alpha 2
chr4_+_7043315 20.65 ENST00000310074.8
ENST00000512388.1
transcriptional adaptor 2B
chr22_-_29315656 20.63 ENST00000401450.3
ENST00000216101.7
RAS like family 10 member A
chr14_-_103521342 20.56 ENST00000553610.5
creatine kinase B
chr19_+_19211949 20.11 ENST00000252575.11
neurocan
chr10_-_73874461 19.88 ENST00000305762.11
calcium/calmodulin dependent protein kinase II gamma
chr1_-_241357171 19.70 ENST00000440928.6
regulator of G protein signaling 7
chr11_-_72642407 19.51 ENST00000376450.7
phosphodiesterase 2A
chr1_-_241357085 19.51 ENST00000366564.5
regulator of G protein signaling 7
chr19_+_589873 19.50 ENST00000251287.3
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
chr12_-_106138946 19.25 ENST00000261402.7
NUAK family kinase 1
chr11_-_72642450 19.04 ENST00000444035.6
ENST00000544570.5
phosphodiesterase 2A
chr17_-_58529303 18.85 ENST00000580844.5
septin 4
chr17_-_58529277 18.74 ENST00000579371.5
septin 4
chr14_+_96039328 18.37 ENST00000553764.1
ENST00000555004.3
ENST00000556728.1
ENST00000553782.1
chromosome 14 open reading frame 132
chr1_-_11654422 18.18 ENST00000354287.5
F-box protein 2
chr12_+_110281116 18.06 ENST00000308664.10
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
chr8_-_119673368 18.03 ENST00000427067.6
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr22_-_36817001 18.01 ENST00000406910.6
ENST00000417718.7
parvalbumin
chr15_+_43692886 17.96 ENST00000434505.5
ENST00000411750.5
creatine kinase, mitochondrial 1A
chr7_+_29479712 17.85 ENST00000412711.6
chimerin 2
chr2_+_219627565 17.49 ENST00000273063.10
solute carrier family 4 member 3
chr7_+_156949704 17.38 ENST00000275820.4
nucleolar protein with MIF4G domain 1
chr10_+_91162958 17.35 ENST00000614189.4
polycomb group ring finger 5
chr5_+_141373878 17.28 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr7_+_29480077 17.24 ENST00000439711.6
ENST00000421775.6
ENST00000424025.4
ENST00000409041.7
chimerin 2
chr15_+_43593054 17.11 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr10_-_73874568 17.06 ENST00000322635.7
ENST00000322680.7
ENST00000394762.7
ENST00000680035.1
calcium/calmodulin dependent protein kinase II gamma
chr17_-_29176752 17.03 ENST00000533112.5
myosin XVIIIA
chr4_-_687325 16.98 ENST00000503156.5
solute carrier family 49 member 3
chr3_+_10026409 16.69 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr13_+_41457543 16.63 ENST00000379359.4
regulator of cell cycle
chr2_+_219627650 16.62 ENST00000317151.7
solute carrier family 4 member 3
chr1_+_203026481 16.61 ENST00000367240.6
PTPRF interacting protein alpha 4
chr12_-_56488350 16.60 ENST00000623608.3
ENST00000610413.4
glutaminase 2
chr1_-_2391535 16.39 ENST00000378531.8
MORN repeat containing 1
chr20_+_38805686 16.12 ENST00000299824.6
ENST00000373331.2
protein phosphatase 1 regulatory subunit 16B
chr1_+_110210272 15.81 ENST00000438661.3
potassium voltage-gated channel subfamily C member 4
chr12_-_49897056 15.74 ENST00000552863.5
Fas apoptotic inhibitory molecule 2
chr3_-_10505508 15.68 ENST00000643662.1
ENST00000397077.6
ENST00000360273.7
ATPase plasma membrane Ca2+ transporting 2
chr2_+_219627622 15.62 ENST00000358055.8
solute carrier family 4 member 3
chr11_-_9003994 15.59 ENST00000309166.8
ENST00000525100.1
ENST00000531090.5
nuclear receptor interacting protein 3
chr5_+_72107453 15.55 ENST00000296755.12
ENST00000511641.2
microtubule associated protein 1B
chr12_-_12338674 15.42 ENST00000545735.1
MANSC domain containing 1
chr11_-_7963646 15.31 ENST00000328600.3
NLR family pyrin domain containing 10
chr19_+_2328663 15.23 ENST00000614794.4
ENST00000613503.5
ENST00000610743.4
ENST00000618220.4
signal peptide peptidase like 2B
chr22_-_36817510 15.13 ENST00000443735.1
parvalbumin
chr7_+_45574358 15.05 ENST00000297323.12
adenylate cyclase 1
chr4_-_86357722 14.93 ENST00000641341.1
ENST00000642038.1
ENST00000641116.1
ENST00000641767.1
ENST00000639242.1
ENST00000638313.1
mitogen-activated protein kinase 10
chr11_-_35360050 14.93 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
solute carrier family 1 member 2
chr11_-_790062 14.91 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr12_-_9115907 14.65 ENST00000318602.12
alpha-2-macroglobulin
chr15_+_43517590 14.62 ENST00000300231.6
microtubule associated protein 1A
chr1_+_236686454 14.58 ENST00000542672.6
ENST00000366578.6
ENST00000682015.1
ENST00000651275.1
actinin alpha 2
chr1_+_84144260 14.52 ENST00000370685.7
protein kinase cAMP-activated catalytic subunit beta
chr6_+_88047822 14.31 ENST00000237201.2
sperm acrosome associated 1
chr1_-_23177683 14.30 ENST00000302291.8
leucine zipper protein 1
chr3_-_49429304 14.28 ENST00000636166.1
ENST00000273598.8
ENST00000436744.2
novel protein
nicolin 1
chr7_+_99558821 14.20 ENST00000424881.5
ENST00000440391.5
ENST00000394163.2
zinc finger protein 655
chr4_-_5893075 13.93 ENST00000324989.12
collapsin response mediator protein 1
chr11_-_707063 13.81 ENST00000683307.1
DEAF1 transcription factor
chr7_+_99558712 13.58 ENST00000425063.5
ENST00000493277.5
zinc finger protein 655
chr20_+_33490073 13.55 ENST00000342704.11
ENST00000375279.6
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr22_+_31753867 13.46 ENST00000535622.6
ENST00000645693.1
ENST00000642974.1
ENST00000645711.1
ENST00000644331.1
ENST00000645560.1
ENST00000437411.6
ENST00000433147.2
ENST00000646755.1
ENST00000382112.8
ENST00000647438.1
ENST00000400248.7
ENST00000456178.6
ENST00000646969.1
ENST00000642696.1
ENST00000647343.1
ENST00000400242.8
ENST00000651528.2
ENST00000645015.1
ENST00000645564.1
ENST00000646465.1
ENST00000400249.7
DEP domain containing 5, GATOR1 subcomplex subunit
chr19_+_40778216 13.44 ENST00000594800.5
ENST00000357052.8
ENST00000602173.5
RAB4B, member RAS oncogene family
chr1_-_202710428 13.42 ENST00000367268.5
synaptotagmin 2
chr5_-_88883147 13.17 ENST00000513252.5
ENST00000506554.5
ENST00000508569.5
ENST00000637732.1
ENST00000504921.7
ENST00000637481.1
ENST00000510942.5
myocyte enhancer factor 2C
chr13_+_112968496 13.12 ENST00000397030.5
MCF.2 cell line derived transforming sequence like
chr8_+_135457442 13.08 ENST00000355849.10
KH RNA binding domain containing, signal transduction associated 3
chr12_-_117099434 13.05 ENST00000541210.5
tescalcin
chr5_-_148654522 13.02 ENST00000377888.8
5-hydroxytryptamine receptor 4
chr10_-_73874502 12.86 ENST00000372765.5
ENST00000351293.7
ENST00000441192.2
ENST00000423381.6
calcium/calmodulin dependent protein kinase II gamma
chr3_-_50567646 12.83 ENST00000426034.5
ENST00000441239.5
chromosome 3 open reading frame 18
chr1_-_149886652 12.73 ENST00000369155.3
H2B clustered histone 21
chr5_+_114056017 12.63 ENST00000512097.9
potassium calcium-activated channel subfamily N member 2
chr5_+_141923813 12.41 ENST00000194118.8
ENST00000432126.7
DAP3 binding cell death enhancer 1
chr12_+_120725796 12.40 ENST00000242592.9
ENST00000411593.2
acyl-CoA dehydrogenase short chain
chr17_-_8163522 12.28 ENST00000404970.3
vesicle associated membrane protein 2
chr7_+_99558632 12.27 ENST00000252713.9
ENST00000449244.5
zinc finger protein 655
chr22_-_44312894 12.24 ENST00000381176.5
shisa like 1
chr22_+_39994926 12.20 ENST00000333407.11
family with sequence similarity 83 member F
chr12_-_48999363 12.15 ENST00000421952.3
dendrin
chr1_-_11848345 12.05 ENST00000376476.1
natriuretic peptide A
chr16_+_16335930 12.03 ENST00000541593.5
novel member of the nuclear pore complex interacting protein NPIP gene family
chr16_-_18372785 12.03 ENST00000531453.6
nuclear pore complex interacting protein family, member A9
chr6_-_27814757 11.94 ENST00000333151.5
H2A clustered histone 14
chr5_+_66958870 11.80 ENST00000405643.5
ENST00000407621.1
ENST00000432426.5
microtubule associated serine/threonine kinase family member 4
chr12_+_119178920 11.79 ENST00000281938.7
heat shock protein family B (small) member 8
chr19_-_55156725 11.75 ENST00000588882.1
ENST00000586858.1
troponin I3, cardiac type
chr14_-_31420531 11.75 ENST00000382464.6
ENST00000543095.7
HEAT repeat containing 5A
chr12_-_117099384 11.72 ENST00000335209.12
tescalcin
chr1_+_1324790 11.64 ENST00000343938.9
ceramide-1-phosphate transfer protein
chr22_+_20117424 11.29 ENST00000402752.5
RAN binding protein 1
chr7_-_945799 11.21 ENST00000611167.4
ArfGAP with dual PH domains 1
chr5_-_16616972 11.16 ENST00000682564.1
ENST00000306320.10
ENST00000682229.1
reticulophagy regulator 1
chrX_-_63785149 11.00 ENST00000671741.2
ENST00000625116.3
ENST00000624355.1
Cdc42 guanine nucleotide exchange factor 9
chr17_-_75848641 10.98 ENST00000586257.5
WW domain binding protein 2
chr1_+_207053229 10.81 ENST00000367080.8
ENST00000367079.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr7_-_105389365 10.66 ENST00000482897.5
SRSF protein kinase 2
chr12_+_21527017 10.60 ENST00000535033.5
spexin hormone
chr10_-_27240743 10.47 ENST00000677901.1
ENST00000677960.1
ENST00000677440.1
ENST00000396271.8
ENST00000677141.1
ENST00000677311.1
ENST00000677667.1
ENST00000677200.1
ENST00000676997.1
ENST00000676511.1
acyl-CoA binding domain containing 5
chr12_+_119178953 10.39 ENST00000674542.1
heat shock protein family B (small) member 8
chr3_+_4493442 10.37 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
inositol 1,4,5-trisphosphate receptor type 1
chr10_-_99430617 10.37 ENST00000370508.7
glutamic-oxaloacetic transaminase 1
chr5_-_16617085 10.32 ENST00000684521.1
reticulophagy regulator 1
chr19_-_12801787 10.20 ENST00000334482.9
ENST00000301522.3
peroxiredoxin 2
chr11_-_66907891 10.20 ENST00000393955.6
pyruvate carboxylase
chr1_-_201023694 10.17 ENST00000332129.6
ENST00000422435.2
ENST00000461742.7
kinesin family member 21B
chr16_-_87493013 10.14 ENST00000671377.2
zinc finger CCHC-type containing 14
chr16_+_85799668 10.11 ENST00000568794.5
ENST00000562336.5
ENST00000253452.8
ENST00000561569.5
ENST00000566405.5
cytochrome c oxidase subunit 4I1
chr6_-_27838362 10.10 ENST00000618958.2
H2A clustered histone 15
chr1_+_27392612 10.02 ENST00000374024.4
G protein-coupled receptor 3
chr1_-_201373229 10.02 ENST00000367317.8
ENST00000360372.8
ENST00000236918.11
ENST00000367315.6
ENST00000658476.1
troponin T2, cardiac type
chr3_+_4493340 9.96 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
inositol 1,4,5-trisphosphate receptor type 1
chr12_+_6535278 9.91 ENST00000396858.5
glyceraldehyde-3-phosphate dehydrogenase
chr17_-_29589536 9.91 ENST00000394869.7
GIT ArfGAP 1
chr19_+_58183029 9.90 ENST00000424679.6
ENST00000617501.5
ENST00000345813.7
zinc finger protein 274
chr22_+_46150590 9.82 ENST00000262735.9
ENST00000420804.5
peroxisome proliferator activated receptor alpha
chr19_+_7914823 9.74 ENST00000565886.2
transforming growth factor beta receptor 3 like
chr5_-_65722094 9.70 ENST00000381007.9
small glutamine rich tetratricopeptide repeat containing beta
chr10_-_49762335 9.69 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr11_-_118176576 9.64 ENST00000278947.6
sodium voltage-gated channel beta subunit 2
chr17_-_29589606 9.64 ENST00000225394.8
GIT ArfGAP 1
chr1_+_2019324 9.59 ENST00000638411.1
ENST00000378585.7
ENST00000640067.1
gamma-aminobutyric acid type A receptor subunit delta
chr21_+_25734948 9.55 ENST00000400075.4
GA binding protein transcription factor subunit alpha
chr10_-_102419934 9.52 ENST00000406432.5
pleckstrin and Sec7 domain containing
chr19_+_48270079 9.48 ENST00000595607.6
zinc finger protein 114
chr12_+_48119787 9.43 ENST00000551804.5
phosphofructokinase, muscle
chr5_+_34929820 9.41 ENST00000642851.1
DnaJ heat shock protein family (Hsp40) member C21
chr5_-_218136 9.29 ENST00000296824.4
coiled-coil domain containing 127
chr7_-_101200912 9.22 ENST00000440203.6
ENST00000379423.3
ENST00000223114.9
monoacylglycerol O-acyltransferase 3
chr9_-_127950716 9.21 ENST00000373084.8
family with sequence similarity 102 member A
chr17_+_32487686 9.20 ENST00000584792.5
cyclin dependent kinase 5 regulatory subunit 1
chr4_-_170026371 9.19 ENST00000361618.4
ENST00000506764.1
microfibril associated protein 3 like
chr7_+_44606578 9.19 ENST00000443864.6
ENST00000447398.5
ENST00000449767.5
ENST00000419661.5
oxoglutarate dehydrogenase
chr20_+_56358938 9.15 ENST00000371384.4
ENST00000437418.1
family with sequence similarity 210 member B
chr16_-_18332662 9.13 ENST00000541810.5
nuclear pore complex interacting protein family member A8
chr1_-_203186677 9.09 ENST00000255409.8
chitinase 3 like 1
chr16_+_67660946 9.04 ENST00000602551.5
ENST00000219255.3
ENST00000458121.7
par-6 family cell polarity regulator alpha
chr3_+_4493471 9.00 ENST00000544951.6
ENST00000650294.1
inositol 1,4,5-trisphosphate receptor type 1
chr5_-_132866884 8.97 ENST00000624492.3
ENST00000621295.4
growth differentiation factor 9
chr5_-_88883420 8.93 ENST00000437473.6
myocyte enhancer factor 2C
chr8_+_141391989 8.92 ENST00000520105.5
ENST00000523147.5
ENST00000521578.6
protein tyrosine phosphatase 4A3
chr12_+_48119323 8.91 ENST00000551339.6
ENST00000629846.2
ENST00000359794.11
ENST00000548345.5
phosphofructokinase, muscle
chr6_-_136792466 8.85 ENST00000359015.5
mitogen-activated protein kinase kinase kinase 5
chr17_-_40100569 8.85 ENST00000246672.4
nuclear receptor subfamily 1 group D member 1
chr8_-_143160015 8.83 ENST00000430474.6
lymphocyte antigen 6 family member H
chr5_+_65722190 8.82 ENST00000380985.10
ENST00000502464.5
neurolysin
chr16_+_14937443 8.82 ENST00000328085.10
nuclear pore complex interacting protein family member A1
chr19_-_49808639 8.79 ENST00000529634.2
fuzzy planar cell polarity protein
chr11_+_1390273 8.76 ENST00000526678.5
BR serine/threonine kinase 2
chr2_-_27495185 8.75 ENST00000264703.4
fibronectin type III domain containing 4
chr6_+_27893411 8.68 ENST00000616182.2
H2B clustered histone 17
chr22_+_30396991 8.65 ENST00000617837.4
ENST00000615189.5
ENST00000405717.7
ENST00000402592.7
SEC14 like lipid binding 2
chr15_-_90932517 8.60 ENST00000330334.7
ENST00000394272.8
ENST00000559898.5
HD domain containing 3
chr5_+_34929572 8.58 ENST00000382021.2
DnaJ heat shock protein family (Hsp40) member C21
chr3_-_184017863 8.51 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr19_+_45079195 8.43 ENST00000591607.1
ENST00000591747.5
ENST00000270257.9
ENST00000391951.2
ENST00000587566.5
gem nuclear organelle associated protein 7
microtubule affinity regulating kinase 4
chr1_+_15438435 8.40 ENST00000375943.6
ENST00000375949.5
chymotrypsin C
chr12_-_11310420 8.40 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
proline rich protein BstNI subfamily 4
chr1_+_54998927 8.36 ENST00000651561.1
barttin CLCNK type accessory subunit beta
chr1_+_28887166 8.34 ENST00000347529.7
erythrocyte membrane protein band 4.1
chr20_-_46651452 8.32 ENST00000279027.9
ENST00000413164.6
solute carrier family 13 member 3
chr1_+_148889403 8.30 ENST00000464103.5
ENST00000534536.5
ENST00000369356.8
ENST00000369354.7
ENST00000369347.8
ENST00000369349.7
ENST00000369351.7
phosphodiesterase 4D interacting protein
chr5_-_108367860 8.27 ENST00000496714.2
F-box and leucine rich repeat protein 17
chr11_-_56292254 8.21 ENST00000641600.1
olfactory receptor family 8 subfamily H member 1
chr16_+_8720706 8.18 ENST00000425191.6
ENST00000569156.5
4-aminobutyrate aminotransferase
chr3_-_49120887 8.15 ENST00000453664.5
ENST00000398888.6
ubiquitin specific peptidase 19
chr12_+_120438107 8.15 ENST00000229379.3
ENST00000551806.1
cytochrome c oxidase subunit 6A1
novel protein
chr20_+_13785017 8.13 ENST00000378106.10
ENST00000463598.1
NADH:ubiquinone oxidoreductase complex assembly factor 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
18.8 320.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
12.4 37.3 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
9.2 55.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
8.1 32.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
6.8 20.3 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
5.9 23.5 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
5.7 17.0 GO:1903028 positive regulation of opsonization(GO:1903028)
5.5 16.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
5.4 16.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
5.3 31.7 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
5.0 34.8 GO:0070560 protein secretion by platelet(GO:0070560)
4.9 14.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
4.9 24.3 GO:1901909 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
4.6 13.9 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
4.5 36.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
3.7 11.1 GO:0009720 detection of hormone stimulus(GO:0009720)
3.7 18.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
3.6 14.6 GO:0030035 microspike assembly(GO:0030035) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
3.5 24.8 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
3.5 10.4 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
3.3 62.3 GO:0015671 oxygen transport(GO:0015671)
3.3 29.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
3.2 19.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
3.1 53.2 GO:0007021 tubulin complex assembly(GO:0007021)
3.1 9.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
3.0 63.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
3.0 14.9 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
3.0 8.9 GO:0060086 circadian temperature homeostasis(GO:0060086)
2.9 8.8 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
2.9 23.4 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
2.9 11.6 GO:0035627 ceramide transport(GO:0035627)
2.9 14.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
2.8 19.5 GO:0071321 cellular response to cGMP(GO:0071321)
2.8 8.3 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
2.8 16.6 GO:0006543 glutamine catabolic process(GO:0006543)
2.7 32.8 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
2.7 21.5 GO:0061709 reticulophagy(GO:0061709)
2.7 50.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
2.6 49.8 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
2.6 10.5 GO:0030242 pexophagy(GO:0030242)
2.6 13.0 GO:0032971 regulation of muscle filament sliding(GO:0032971)
2.6 10.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.5 53.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
2.5 7.6 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
2.5 7.5 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
2.5 9.8 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.5 7.4 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
2.4 14.5 GO:0097338 response to clozapine(GO:0097338)
2.3 6.8 GO:0071529 cementum mineralization(GO:0071529)
2.2 6.6 GO:1905237 cellular response to mycotoxin(GO:0036146) response to antineoplastic agent(GO:0097327) response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
2.2 8.8 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
2.1 19.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
2.1 2.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.1 33.7 GO:0038003 opioid receptor signaling pathway(GO:0038003)
2.1 21.0 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
2.0 6.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
2.0 8.1 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
2.0 4.0 GO:0046110 xanthine metabolic process(GO:0046110)
2.0 6.0 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
2.0 5.9 GO:1905073 uterine wall breakdown(GO:0042704) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.9 5.8 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
1.9 24.7 GO:0006600 creatine metabolic process(GO:0006600)
1.9 5.7 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.9 9.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
1.9 5.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.8 11.0 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
1.8 10.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
1.8 9.0 GO:2000870 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
1.8 10.7 GO:0035063 nuclear speck organization(GO:0035063)
1.8 10.6 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
1.8 7.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
1.7 5.2 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.7 6.9 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
1.7 3.4 GO:0046959 habituation(GO:0046959)
1.7 6.8 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
1.7 16.7 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.7 5.0 GO:0048073 regulation of eye pigmentation(GO:0048073)
1.6 93.1 GO:0015701 bicarbonate transport(GO:0015701)
1.6 6.4 GO:0007538 primary sex determination(GO:0007538)
1.6 7.9 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
1.5 7.7 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.5 4.6 GO:0061760 antifungal innate immune response(GO:0061760)
1.5 15.1 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
1.5 7.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
1.4 4.3 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.4 5.8 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.4 5.8 GO:0021571 rhombomere 5 development(GO:0021571)
1.4 4.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.4 15.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
1.4 9.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
1.4 4.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
1.3 14.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.3 6.7 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.3 5.3 GO:0046952 ketone body catabolic process(GO:0046952)
1.3 7.8 GO:0042636 negative regulation of hair cycle(GO:0042636)
1.3 7.7 GO:0007341 penetration of zona pellucida(GO:0007341)
1.3 22.9 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
1.2 18.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
1.2 9.6 GO:0046684 response to pyrethroid(GO:0046684)
1.2 3.6 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
1.2 17.9 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
1.2 4.8 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
1.2 7.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.2 7.0 GO:0006196 AMP catabolic process(GO:0006196)
1.1 9.1 GO:0006572 tyrosine catabolic process(GO:0006572)
1.1 5.7 GO:0042415 norepinephrine metabolic process(GO:0042415)
1.1 9.0 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
1.1 15.7 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
1.1 8.7 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
1.1 2.2 GO:0033058 directional locomotion(GO:0033058)
1.1 4.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
1.1 10.7 GO:2000773 negative regulation of cellular senescence(GO:2000773)
1.1 14.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.0 15.7 GO:0007258 JUN phosphorylation(GO:0007258)
1.0 4.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.0 5.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
1.0 5.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
1.0 4.0 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
1.0 6.9 GO:0006662 glycerol ether metabolic process(GO:0006662)
1.0 4.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
1.0 2.9 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.0 14.3 GO:0001842 neural fold formation(GO:0001842)
0.9 14.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.9 4.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.9 2.7 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.9 20.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.9 2.6 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.9 3.5 GO:0072014 proximal tubule development(GO:0072014)
0.9 3.4 GO:0052330 induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.8 15.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.8 5.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.8 9.9 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.8 3.3 GO:1902938 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.8 4.1 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.8 19.5 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.8 8.9 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.8 3.2 GO:0009822 alkaloid catabolic process(GO:0009822) calcitriol biosynthetic process from calciol(GO:0036378)
0.8 17.4 GO:0048820 hair follicle maturation(GO:0048820)
0.8 8.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.8 7.0 GO:0016198 axon choice point recognition(GO:0016198)
0.7 9.7 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.7 20.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.7 6.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.7 2.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.7 2.8 GO:0050957 equilibrioception(GO:0050957)
0.7 7.6 GO:0001787 natural killer cell proliferation(GO:0001787) T-helper 17 cell lineage commitment(GO:0072540)
0.7 2.0 GO:0044266 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.7 9.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.7 8.8 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.7 13.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.7 6.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.6 8.4 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.6 16.2 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.6 5.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.6 13.9 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.6 13.8 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.6 11.5 GO:0032098 regulation of appetite(GO:0032098)
0.6 3.0 GO:0071316 olfactory nerve development(GO:0021553) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) cellular response to nicotine(GO:0071316)
0.6 5.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.6 13.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.6 5.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.6 4.0 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.6 10.0 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.6 8.9 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.5 21.6 GO:0042417 dopamine metabolic process(GO:0042417)
0.5 4.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.5 1.6 GO:0060974 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.5 4.6 GO:0032790 ribosome disassembly(GO:0032790)
0.5 3.5 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.5 6.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.5 1.9 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.5 7.7 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.5 16.1 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.5 4.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.5 32.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.5 12.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.4 10.2 GO:0070207 protein homotrimerization(GO:0070207)
0.4 16.6 GO:0014047 glutamate secretion(GO:0014047)
0.4 9.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.4 2.2 GO:0051971 response to L-ascorbic acid(GO:0033591) positive regulation of transmission of nerve impulse(GO:0051971)
0.4 1.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.4 5.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 11.2 GO:0007618 mating(GO:0007618)
0.4 7.9 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.4 2.9 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.4 11.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.4 3.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.4 13.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.4 1.5 GO:0072180 pronephric nephron tubule development(GO:0039020) regulation of endodermal cell fate specification(GO:0042663) hepatoblast differentiation(GO:0061017) mesonephric duct morphogenesis(GO:0072180)
0.4 1.5 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.4 5.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.4 28.0 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.4 1.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4 3.0 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.4 6.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 4.4 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.4 5.0 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.4 13.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.4 3.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.4 7.7 GO:0070932 histone H3 deacetylation(GO:0070932)
0.3 2.7 GO:0044062 regulation of excretion(GO:0044062)
0.3 6.2 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.3 0.7 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.3 7.1 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.3 9.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 5.3 GO:0031033 myosin filament organization(GO:0031033)
0.3 1.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.3 18.2 GO:0010107 potassium ion import(GO:0010107)
0.3 2.6 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 3.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.3 1.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.3 10.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.3 6.0 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.3 20.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3 2.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 0.3 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.3 1.7 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.3 3.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.3 0.8 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.3 0.5 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.3 6.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.3 7.1 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.3 7.2 GO:0060384 innervation(GO:0060384)
0.3 7.7 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.2 5.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 5.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 3.7 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2 4.6 GO:0006972 hyperosmotic response(GO:0006972)
0.2 8.6 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.2 1.6 GO:1902166 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.2 3.8 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.2 1.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 3.1 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.2 5.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 6.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 0.4 GO:0071554 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.2 5.7 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 32.9 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.2 4.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 1.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 14.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 163.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.2 4.7 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2 2.7 GO:0032196 transposition(GO:0032196)
0.2 0.7 GO:0098711 iron ion import into cell(GO:0097459) iron ion import across plasma membrane(GO:0098711)
0.2 11.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 10.0 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.2 6.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 0.8 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 11.1 GO:0046323 glucose import(GO:0046323)
0.1 2.7 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 4.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 4.8 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 1.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 2.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.4 GO:0097237 cellular response to toxic substance(GO:0097237)
0.1 12.6 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 6.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 5.3 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.1 5.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.7 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 8.3 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 2.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 15.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.3 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 3.5 GO:0010761 fibroblast migration(GO:0010761)
0.1 5.9 GO:0050909 sensory perception of taste(GO:0050909)
0.1 27.7 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.1 2.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 2.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 10.4 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 5.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 2.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.9 GO:1904469 regulation of tumor necrosis factor secretion(GO:1904467) positive regulation of tumor necrosis factor secretion(GO:1904469) tumor necrosis factor secretion(GO:1990774)
0.1 5.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 1.2 GO:0007100 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.1 1.3 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 1.1 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.6 GO:0015695 organic cation transport(GO:0015695)
0.1 4.0 GO:0042472 inner ear morphogenesis(GO:0042472)
0.1 0.6 GO:0036315 cellular response to sterol(GO:0036315)
0.1 0.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.5 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.3 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.9 GO:0007032 endosome organization(GO:0007032)
0.0 1.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 2.6 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 3.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.4 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.2 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.7 GO:0031529 ruffle organization(GO:0031529)
0.0 1.2 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.2 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.4 GO:0009584 detection of visible light(GO:0009584)
0.0 0.5 GO:0016266 O-glycan processing(GO:0016266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
14.1 56.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
9.1 36.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
5.3 31.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
5.2 83.4 GO:0097512 cardiac myofibril(GO:0097512)
4.7 71.1 GO:0097433 dense body(GO:0097433)
4.7 37.3 GO:0097450 astrocyte end-foot(GO:0097450)
3.7 7.5 GO:0043159 acrosomal matrix(GO:0043159)
3.4 84.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
3.3 52.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
3.1 18.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
3.0 15.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
2.1 14.8 GO:1990130 Iml1 complex(GO:1990130)
2.0 8.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
1.9 13.4 GO:0042584 chromaffin granule membrane(GO:0042584)
1.8 9.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.8 26.7 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
1.8 8.9 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.7 13.4 GO:0032593 insulin-responsive compartment(GO:0032593)
1.7 5.0 GO:0031085 BLOC-3 complex(GO:0031085)
1.6 14.7 GO:0032133 chromosome passenger complex(GO:0032133)
1.4 4.2 GO:0098536 deuterosome(GO:0098536)
1.4 72.3 GO:0048786 presynaptic active zone(GO:0048786)
1.4 313.1 GO:0030426 growth cone(GO:0030426)
1.3 20.7 GO:0030914 STAGA complex(GO:0030914)
1.2 3.7 GO:0097224 sperm connecting piece(GO:0097224)
1.1 7.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.1 8.9 GO:0005579 membrane attack complex(GO:0005579)
1.1 7.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.1 14.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.1 5.3 GO:0019815 B cell receptor complex(GO:0019815)
1.1 51.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.0 4.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.0 3.0 GO:0070701 mucus layer(GO:0070701)
1.0 6.8 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
1.0 67.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.9 13.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.9 8.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.8 6.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.7 13.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.7 2.8 GO:0002139 stereocilia coupling link(GO:0002139)
0.7 5.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.7 6.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.6 12.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.6 10.6 GO:0031045 dense core granule(GO:0031045)
0.6 18.5 GO:0042629 mast cell granule(GO:0042629)
0.6 41.8 GO:0042734 presynaptic membrane(GO:0042734)
0.6 76.5 GO:0043679 axon terminus(GO:0043679)
0.6 3.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.6 3.5 GO:0005927 muscle tendon junction(GO:0005927)
0.6 14.6 GO:0031143 pseudopodium(GO:0031143)
0.6 11.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.5 8.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.5 14.3 GO:0002080 acrosomal membrane(GO:0002080)
0.5 6.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 14.9 GO:0030673 axolemma(GO:0030673)
0.5 5.9 GO:0005833 hemoglobin complex(GO:0005833)
0.5 16.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.4 5.8 GO:0036020 endolysosome membrane(GO:0036020)
0.4 26.7 GO:0005801 cis-Golgi network(GO:0005801)
0.4 4.9 GO:0005869 dynactin complex(GO:0005869)
0.4 1.2 GO:0016939 plus-end kinesin complex(GO:0005873) kinesin II complex(GO:0016939)
0.4 9.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 3.4 GO:0097452 GAIT complex(GO:0097452)
0.4 20.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.4 55.6 GO:0032587 ruffle membrane(GO:0032587)
0.3 6.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 10.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.3 21.8 GO:0005802 trans-Golgi network(GO:0005802)
0.3 2.7 GO:0000813 ESCRT I complex(GO:0000813)
0.3 5.1 GO:0005861 troponin complex(GO:0005861)
0.3 4.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 2.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 18.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 2.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 4.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 4.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 8.0 GO:0034451 centriolar satellite(GO:0034451)
0.2 3.8 GO:0036038 MKS complex(GO:0036038)
0.2 21.6 GO:0035579 specific granule membrane(GO:0035579)
0.2 25.2 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.2 GO:0097504 SMN complex(GO:0032797) Gemini of coiled bodies(GO:0097504)
0.2 2.1 GO:0097440 apical dendrite(GO:0097440)
0.2 7.8 GO:0016592 mediator complex(GO:0016592)
0.2 19.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 81.5 GO:0043025 neuronal cell body(GO:0043025)
0.2 1.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 2.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 5.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 3.7 GO:0032420 stereocilium(GO:0032420)
0.2 8.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 11.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 7.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 17.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 3.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 4.0 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.7 GO:0001741 XY body(GO:0001741)
0.1 6.5 GO:0001533 cornified envelope(GO:0001533)
0.1 4.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 6.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 11.5 GO:0016234 inclusion body(GO:0016234)
0.1 3.6 GO:0008305 integrin complex(GO:0008305)
0.1 0.6 GO:0031905 early endosome lumen(GO:0031905)
0.1 15.3 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 10.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 4.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 2.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 10.0 GO:0098794 postsynapse(GO:0098794)
0.1 9.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 160.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 2.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 5.3 GO:0005884 actin filament(GO:0005884)
0.1 3.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 28.9 GO:0000790 nuclear chromatin(GO:0000790)
0.1 4.0 GO:0034703 cation channel complex(GO:0034703)
0.1 5.0 GO:0043235 receptor complex(GO:0043235)
0.1 5.1 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 4.3 GO:0031902 late endosome membrane(GO:0031902)
0.1 2.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 3.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.2 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 3.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.7 GO:0005604 basement membrane(GO:0005604)
0.0 33.2 GO:0005730 nucleolus(GO:0005730)
0.0 3.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.4 GO:0030496 midbody(GO:0030496)
0.0 61.4 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.0 79.7 GO:0004111 creatine kinase activity(GO:0004111)
5.5 65.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
5.0 15.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
4.9 29.5 GO:0030172 troponin C binding(GO:0030172)
4.9 14.7 GO:0019959 interleukin-8 binding(GO:0019959)
4.9 24.3 GO:0052847 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
4.7 61.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
4.6 13.8 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
4.5 18.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
4.4 88.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
4.2 62.3 GO:0005344 oxygen transporter activity(GO:0005344)
3.9 19.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
3.8 49.8 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
3.7 14.9 GO:0005163 nerve growth factor receptor binding(GO:0005163)
3.7 29.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
3.5 24.6 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
3.4 17.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
3.2 38.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
3.1 9.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
3.1 9.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
3.1 107.0 GO:0017075 syntaxin-1 binding(GO:0017075)
3.0 14.8 GO:0001594 trace-amine receptor activity(GO:0001594)
2.9 14.6 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
2.9 11.6 GO:0097001 ceramide binding(GO:0097001)
2.9 8.6 GO:0008431 vitamin E binding(GO:0008431)
2.8 8.3 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
2.8 11.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
2.8 16.6 GO:0004359 glutaminase activity(GO:0004359)
2.6 23.5 GO:0016015 morphogen activity(GO:0016015)
2.5 10.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
2.5 7.5 GO:0042806 amidase activity(GO:0004040) fucose binding(GO:0042806)
2.5 32.2 GO:0046870 cadmium ion binding(GO:0046870)
2.4 31.7 GO:0008199 ferric iron binding(GO:0008199)
2.4 14.3 GO:0003796 lysozyme activity(GO:0003796)
2.4 7.1 GO:0004967 glucagon receptor activity(GO:0004967)
2.3 18.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
2.2 15.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
2.0 8.2 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
2.0 7.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.0 58.5 GO:0005212 structural constituent of eye lens(GO:0005212)
1.8 10.8 GO:0008443 6-phosphofructo-2-kinase activity(GO:0003873) phosphofructokinase activity(GO:0008443)
1.8 26.9 GO:1903136 cuprous ion binding(GO:1903136)
1.7 6.9 GO:0035473 lipase binding(GO:0035473)
1.7 5.1 GO:0033142 progesterone receptor binding(GO:0033142)
1.7 48.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.6 14.7 GO:0035174 histone serine kinase activity(GO:0035174)
1.6 7.8 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
1.5 4.6 GO:0004047 aminomethyltransferase activity(GO:0004047)
1.5 6.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
1.5 44.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.5 7.6 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.5 7.3 GO:0004370 glycerol kinase activity(GO:0004370)
1.4 4.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
1.4 6.9 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113) peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.4 23.4 GO:0003680 AT DNA binding(GO:0003680)
1.3 25.4 GO:0031005 filamin binding(GO:0031005)
1.3 10.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.3 12.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.2 3.7 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.2 5.0 GO:0004773 steryl-sulfatase activity(GO:0004773)
1.2 15.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.2 9.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.2 6.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.2 5.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.2 7.1 GO:0009378 four-way junction helicase activity(GO:0009378)
1.1 3.4 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
1.1 6.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.1 7.7 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
1.1 6.6 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
1.1 8.5 GO:0038064 collagen receptor activity(GO:0038064)
1.1 14.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.1 3.2 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
1.1 7.4 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
1.1 5.3 GO:0008410 CoA-transferase activity(GO:0008410)
1.0 5.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
1.0 3.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.0 9.1 GO:0034235 GPI anchor binding(GO:0034235)
1.0 4.0 GO:0004031 aldehyde oxidase activity(GO:0004031)
1.0 8.9 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
1.0 7.9 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
1.0 2.9 GO:0005137 interleukin-5 receptor binding(GO:0005137)
1.0 5.8 GO:0016361 activin receptor activity, type I(GO:0016361)
0.9 17.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.9 9.1 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.9 9.8 GO:0051525 NFAT protein binding(GO:0051525)
0.9 3.5 GO:0035939 microsatellite binding(GO:0035939)
0.9 5.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.9 6.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.9 6.9 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.9 17.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.9 10.2 GO:0004075 biotin carboxylase activity(GO:0004075)
0.8 8.2 GO:0005549 odorant binding(GO:0005549)
0.8 5.6 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.8 4.0 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.8 30.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.8 4.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.8 13.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.8 4.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.7 62.6 GO:0043621 protein self-association(GO:0043621)
0.7 7.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.7 5.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.7 3.5 GO:0004920 type I interferon receptor activity(GO:0004905) interleukin-10 receptor activity(GO:0004920)
0.7 55.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.7 2.0 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.7 3.3 GO:0004771 sterol esterase activity(GO:0004771)
0.7 17.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.7 24.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 8.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.6 7.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.6 3.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.6 10.3 GO:0032052 bile acid binding(GO:0032052)
0.6 12.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.6 3.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.6 1.8 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.6 7.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.6 1.7 GO:0008142 oxysterol binding(GO:0008142)
0.6 7.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.6 3.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.6 8.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.6 5.1 GO:0048495 Roundabout binding(GO:0048495)
0.5 5.9 GO:0004985 opioid receptor activity(GO:0004985)
0.5 13.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.5 30.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.5 3.7 GO:0005497 androgen binding(GO:0005497)
0.5 14.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.5 10.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.5 7.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.5 8.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.5 2.6 GO:0004803 transposase activity(GO:0004803)
0.5 4.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.5 1.4 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.5 9.4 GO:0016805 dipeptidase activity(GO:0016805)
0.5 4.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.5 3.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 1.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 4.0 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 5.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.4 2.6 GO:0004977 melanocortin receptor activity(GO:0004977)
0.4 6.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 1.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.4 2.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.4 14.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.4 1.6 GO:0061714 folic acid receptor activity(GO:0061714)
0.4 8.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.4 4.5 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.4 3.7 GO:0032027 myosin light chain binding(GO:0032027)
0.4 8.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 5.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.4 3.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.4 2.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 8.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 5.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.4 4.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.4 3.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.4 5.3 GO:0043522 cAMP response element binding protein binding(GO:0008140) leucine zipper domain binding(GO:0043522)
0.4 12.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 19.6 GO:0005158 insulin receptor binding(GO:0005158)
0.3 9.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.3 42.0 GO:0035591 signaling adaptor activity(GO:0035591)
0.3 5.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 6.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 3.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.3 1.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 1.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 5.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 19.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.3 3.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 9.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 9.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 16.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 7.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 2.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 20.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 15.1 GO:0070412 R-SMAD binding(GO:0070412)
0.2 6.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 4.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 5.8 GO:0071837 HMG box domain binding(GO:0071837)
0.2 2.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 2.6 GO:0015266 protein channel activity(GO:0015266)
0.2 11.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 3.0 GO:0031432 titin binding(GO:0031432)
0.2 0.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 0.7 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 6.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.4 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 1.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 0.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 3.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 9.4 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
0.2 3.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 8.6 GO:0043531 ADP binding(GO:0043531)
0.2 17.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.6 GO:0019534 toxin transporter activity(GO:0019534)
0.1 13.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 2.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.5 GO:0032183 SUMO binding(GO:0032183)
0.1 3.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 22.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.8 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 35.2 GO:0005096 GTPase activator activity(GO:0005096)
0.1 9.1 GO:0002039 p53 binding(GO:0002039)
0.1 5.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 3.7 GO:0004601 peroxidase activity(GO:0004601)
0.1 3.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 28.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 6.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 3.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 7.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 21.0 GO:0008017 microtubule binding(GO:0008017)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.6 GO:0035326 enhancer binding(GO:0035326)
0.1 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 5.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 4.3 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)
0.1 6.1 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 13.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 3.6 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 3.7 GO:0001159 core promoter proximal region DNA binding(GO:0001159)
0.0 13.1 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 8.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 111.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
1.6 241.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.8 35.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.7 19.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.6 43.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.6 2.9 PID IL5 PATHWAY IL5-mediated signaling events
0.6 25.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.5 20.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.5 8.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.4 16.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 11.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.4 32.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.4 23.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 10.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.4 20.5 PID LKB1 PATHWAY LKB1 signaling events
0.4 16.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.4 8.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.4 7.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 2.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 7.9 PID CONE PATHWAY Visual signal transduction: Cones
0.4 1.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4 9.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 9.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 25.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.3 14.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.3 11.7 PID ALK1 PATHWAY ALK1 signaling events
0.3 10.9 PID RAS PATHWAY Regulation of Ras family activation
0.3 3.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 7.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 11.2 PID ARF6 PATHWAY Arf6 signaling events
0.2 11.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 7.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 5.1 PID IL27 PATHWAY IL27-mediated signaling events
0.2 6.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 1.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 19.2 PID AP1 PATHWAY AP-1 transcription factor network
0.2 10.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 9.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 5.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 5.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 4.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2 4.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 5.0 PID TNF PATHWAY TNF receptor signaling pathway
0.1 3.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 8.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 6.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 4.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 13.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.3 ST GA12 PATHWAY G alpha 12 Pathway
0.1 2.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.5 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 84.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
1.6 44.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.4 33.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.4 16.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.2 15.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
1.1 16.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.1 14.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.0 44.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.9 34.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.9 20.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.8 23.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.7 20.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.7 48.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.7 8.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.7 12.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.6 20.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.6 13.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.6 44.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.6 80.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.6 15.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.6 9.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 4.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.5 64.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.5 9.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 18.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 16.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.5 5.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.4 9.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.4 8.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.4 12.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.4 9.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.4 22.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 15.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 2.7 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 4.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 10.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.3 7.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.3 9.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 7.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.3 17.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3 4.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 7.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 3.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 6.7 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 9.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 2.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 5.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 6.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 33.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 7.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 2.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 4.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 3.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 33.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 4.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 6.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 5.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 3.5 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.2 3.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 4.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 2.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 5.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 5.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 49.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 4.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 10.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 2.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 30.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 4.0 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 10.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 4.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 4.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 0.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 2.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins