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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for OLIG1

Z-value: 0.57

Motif logo

Transcription factors associated with OLIG1

Gene Symbol Gene ID Gene Info
ENSG00000184221.13 OLIG1

Activity profile of OLIG1 motif

Sorted Z-values of OLIG1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_111793871 8.51 ENST00000368667.6
FYN proto-oncogene, Src family tyrosine kinase
chr19_+_18097763 8.42 ENST00000262811.10
microtubule associated serine/threonine kinase 3
chr3_-_39280432 7.99 ENST00000542107.5
ENST00000435290.1
C-X3-C motif chemokine receptor 1
chr3_-_18438767 7.91 ENST00000454909.6
SATB homeobox 1
chr1_+_158930778 7.30 ENST00000458222.5
pyrin and HIN domain family member 1
chr1_+_244051275 7.14 ENST00000358704.4
zinc finger and BTB domain containing 18
chr3_-_39281261 6.49 ENST00000541347.5
ENST00000412814.1
C-X3-C motif chemokine receptor 1
chr5_-_11588842 6.44 ENST00000503622.5
catenin delta 2
chr3_-_121660892 6.35 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr6_-_69699124 6.10 ENST00000651675.1
LMBR1 domain containing 1
chr3_-_98522514 5.90 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr2_+_10368764 5.87 ENST00000620771.4
hippocalcin like 1
chr3_-_33659097 5.87 ENST00000461133.8
ENST00000496954.2
cytoplasmic linker associated protein 2
chr2_+_180981108 5.74 ENST00000602710.5
ubiquitin conjugating enzyme E2 E3
chr2_+_10368645 5.69 ENST00000613496.4
hippocalcin like 1
chr7_-_140479476 5.66 ENST00000443720.6
ENST00000255977.7
makorin ring finger protein 1
chr3_-_108058361 5.59 ENST00000398258.7
CD47 molecule
chr10_+_69278492 5.33 ENST00000643399.2
hexokinase 1
chr2_+_201129318 5.24 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr10_-_46030585 5.08 ENST00000580070.5
ENST00000578454.5
ENST00000585056.5
ENST00000579039.2
ENST00000581486.6
nuclear receptor coactivator 4
chr17_-_42018488 5.07 ENST00000589773.5
ENST00000674214.1
DnaJ heat shock protein family (Hsp40) member C7
chr5_-_11589019 5.01 ENST00000511377.5
catenin delta 2
chr1_+_50103903 4.84 ENST00000371827.5
ELAV like RNA binding protein 4
chr3_+_62319037 4.84 ENST00000494481.5
chromosome 3 open reading frame 14
chr3_+_62318983 4.67 ENST00000232519.9
ENST00000462069.6
ENST00000465142.5
chromosome 3 open reading frame 14
chr7_-_36985060 4.50 ENST00000396040.6
engulfment and cell motility 1
chr19_-_54364983 4.37 ENST00000434277.6
leukocyte associated immunoglobulin like receptor 1
chr5_-_170297746 4.37 ENST00000046794.10
lymphocyte cytosolic protein 2
chr1_-_19484635 4.27 ENST00000433834.5
capping actin protein of muscle Z-line subunit beta
chr3_+_150603279 4.12 ENST00000615547.4
ENST00000477889.5
ENST00000471696.6
ENST00000485923.1
selenoprotein T
chr7_+_107891135 4.11 ENST00000639772.1
ENST00000440410.5
ENST00000437604.6
ENST00000205402.10
dihydrolipoamide dehydrogenase
chr2_+_218245426 4.09 ENST00000456575.1
actin related protein 2/3 complex subunit 2
chr4_-_73223082 4.05 ENST00000509867.6
ankyrin repeat domain 17
chr3_+_9797651 3.92 ENST00000453882.1
ARPC4-TTLL3 readthrough
chr6_-_28923932 3.88 ENST00000377199.4
ENST00000377194.7
tripartite motif containing 27
chr1_-_21050952 3.85 ENST00000264211.12
eukaryotic translation initiation factor 4 gamma 3
chr1_+_153778178 3.81 ENST00000532853.5
solute carrier family 27 member 3
chr3_-_33659441 3.80 ENST00000650653.1
ENST00000480013.6
cytoplasmic linker associated protein 2
chr8_-_23457618 3.71 ENST00000358689.9
ENST00000518718.1
ectonucleoside triphosphate diphosphohydrolase 4
chr11_+_65638085 3.67 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1
chr2_+_129979641 3.61 ENST00000410061.4
RAB6C, member RAS oncogene family
chr3_+_184300564 3.57 ENST00000435761.5
ENST00000439383.5
proteasome 26S subunit, non-ATPase 2
chr2_+_17539964 3.57 ENST00000457525.5
visinin like 1
chr6_+_69232406 3.42 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr5_+_119476530 3.42 ENST00000645099.1
ENST00000513628.5
hydroxysteroid 17-beta dehydrogenase 4
chr17_+_36486629 3.41 ENST00000619730.4
zinc finger HIT-type containing 3
chr2_+_148978361 3.36 ENST00000678720.1
ENST00000678856.1
ENST00000677080.1
kinesin family member 5C
chr4_+_159267737 3.35 ENST00000264431.8
Rap guanine nucleotide exchange factor 2
chr14_+_24070837 3.32 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
copine 6
chr20_-_64079906 3.26 ENST00000332298.9
regulator of G protein signaling 19
chr7_+_65373839 3.21 ENST00000431504.1
ENST00000328747.12
zinc finger protein 92
chr9_-_127873462 2.97 ENST00000223836.10
adenylate kinase 1
chr12_-_7936177 2.95 ENST00000544291.1
ENST00000075120.12
solute carrier family 2 member 3
chrX_+_65667645 2.94 ENST00000360270.7
moesin
chr3_-_197226351 2.89 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr19_+_19458458 2.88 ENST00000358713.7
GATA zinc finger domain containing 2A
chr1_+_9651723 2.84 ENST00000377346.9
ENST00000536656.5
ENST00000628140.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr11_+_17295322 2.82 ENST00000458064.6
ENST00000622082.4
nucleobindin 2
chr4_+_113292838 2.81 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr2_+_171687501 2.81 ENST00000508530.5
dynein cytoplasmic 1 intermediate chain 2
chr4_+_113292925 2.77 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr10_+_134465 2.77 ENST00000439456.5
ENST00000397962.8
ENST00000309776.8
ENST00000397959.7
zinc finger MYND-type containing 11
chr17_+_68035636 2.76 ENST00000676857.1
ENST00000676594.1
ENST00000678388.1
karyopherin subunit alpha 2
chr14_+_88005128 2.76 ENST00000267549.5
G protein-coupled receptor 65
chr1_-_23980345 2.75 ENST00000484146.6
serine and arginine rich splicing factor 10
chr3_-_50350710 2.71 ENST00000232501.8
NPR2 like, GATOR1 complex subunit
chr1_+_12464912 2.69 ENST00000543766.2
vacuolar protein sorting 13 homolog D
chr22_+_37282464 2.68 ENST00000402997.5
ENST00000405206.3
ENST00000248901.11
cytohesin 4
chr15_+_88635626 2.65 ENST00000379224.10
interferon stimulated exonuclease gene 20
chr17_+_47971105 2.62 ENST00000338399.9
ENST00000578018.5
ENST00000579175.5
CDK5 regulatory subunit associated protein 3
chr6_+_31586269 2.55 ENST00000438075.7
leukocyte specific transcript 1
chr8_+_21966215 2.54 ENST00000433566.8
exportin 7
chr6_+_2999984 2.53 ENST00000380441.5
ENST00000380454.8
N-ribosyldihydronicotinamide:quinone reductase 2
chr6_-_34426052 2.40 ENST00000344700.8
ENST00000644700.1
ENST00000648437.1
ENST00000644393.1
ENST00000639725.1
ribosomal protein S10
RPS10-NUDT3 readthrough
chr2_+_171687457 2.37 ENST00000397119.8
ENST00000410079.7
ENST00000438879.5
dynein cytoplasmic 1 intermediate chain 2
chr7_+_116862552 2.34 ENST00000361183.8
ENST00000639546.1
ENST00000490693.5
capping actin protein of muscle Z-line subunit alpha 2
chr22_+_46674593 2.30 ENST00000408031.1
GRAM domain containing 4
chr6_-_34426020 2.23 ENST00000621356.3
ENST00000494077.6
ENST00000639877.1
ribosomal protein S10
RPS10-NUDT3 readthrough
chr6_-_31958852 2.22 ENST00000375425.9
ENST00000426722.5
negative elongation factor complex member E
chr7_+_140696696 2.22 ENST00000247866.9
ENST00000464566.5
NADH:ubiquinone oxidoreductase subunit B2
chr5_+_157180816 2.22 ENST00000422843.8
IL2 inducible T cell kinase
chr9_-_124415421 2.22 ENST00000259457.8
ENST00000441097.1
proteasome 20S subunit beta 7
chr14_-_60165293 2.18 ENST00000554101.5
ENST00000557137.1
dehydrogenase/reductase 7
chr7_+_111091006 2.17 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr19_-_54281082 2.16 ENST00000314446.10
leukocyte immunoglobulin like receptor B2
chr15_+_76995118 2.14 ENST00000558012.6
ENST00000379595.7
proline-serine-threonine phosphatase interacting protein 1
chr6_-_31958935 2.14 ENST00000441998.5
ENST00000444811.6
ENST00000375429.8
negative elongation factor complex member E
chr1_+_110339462 2.11 ENST00000617047.1
RNA binding motif protein 15
chr6_+_12716760 2.11 ENST00000332995.12
phosphatase and actin regulator 1
chr6_+_12716801 2.09 ENST00000674595.1
phosphatase and actin regulator 1
chr6_+_31586124 2.08 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
leukocyte specific transcript 1
chr7_+_111091119 2.06 ENST00000308478.10
leucine rich repeat neuronal 3
chr2_+_190927649 2.05 ENST00000409428.5
ENST00000409215.5
glutaminase
chr17_-_82037677 2.01 ENST00000581584.5
ENST00000577712.5
ENST00000582900.5
ENST00000579155.1
ENST00000306869.7
dicarbonyl and L-xylulose reductase
chr2_+_197453423 2.01 ENST00000263960.6
coenzyme Q10B
chr1_+_110339323 2.00 ENST00000602849.1
ENST00000487146.8
ENST00000618772.4
ENST00000369784.9
ENST00000650953.2
ENST00000652342.2
ENST00000654015.1
RNA binding motif protein 15
chr6_+_30571393 1.98 ENST00000376545.7
ENST00000441867.6
ENST00000468958.1
ENST00000326195.13
ATP binding cassette subfamily F member 1
chrX_+_108045050 1.97 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr5_+_115841878 1.96 ENST00000316788.12
adaptor related protein complex 3 subunit sigma 1
chr1_+_236394268 1.95 ENST00000334232.9
EDAR associated death domain
chr1_+_103750406 1.89 ENST00000370079.3
amylase alpha 1C
chr6_+_2999961 1.84 ENST00000338130.7
N-ribosyldihydronicotinamide:quinone reductase 2
chr15_-_66524518 1.84 ENST00000568588.5
ribosomal protein L4
chr1_+_159302321 1.80 ENST00000368114.1
Fc fragment of IgE receptor Ia
chr1_+_91500827 1.78 ENST00000234626.11
cell division cycle 7
chrX_+_108044967 1.76 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr6_+_2999885 1.76 ENST00000397717.7
ENST00000380455.11
N-ribosyldihydronicotinamide:quinone reductase 2
chr19_-_54281145 1.74 ENST00000434421.5
ENST00000391749.4
leukocyte immunoglobulin like receptor B2
chr1_+_91501097 1.69 ENST00000428239.5
ENST00000426137.1
cell division cycle 7
chr6_+_37433197 1.68 ENST00000455891.5
ENST00000373451.9
cap methyltransferase 1
chr3_+_112990956 1.65 ENST00000383678.8
ENST00000383677.7
ENST00000619116.4
GTP binding protein 8 (putative)
chr13_-_99258366 1.64 ENST00000397470.5
ENST00000397473.7
G protein-coupled receptor 18
chr2_-_182522556 1.63 ENST00000435564.5
phosphodiesterase 1A
chr2_+_135741814 1.63 ENST00000272638.14
UBX domain protein 4
chr8_+_22057857 1.63 ENST00000517305.4
ENST00000265800.9
ENST00000517418.5
dematin actin binding protein
chr19_-_1021114 1.63 ENST00000333175.9
ENST00000356663.8
transmembrane protein 259
chr1_+_147242654 1.62 ENST00000652587.1
ENST00000361293.10
ENST00000369258.8
ENST00000369259.4
ENST00000650714.1
ENST00000639534.1
chromodomain helicase DNA binding protein 1 like
chr3_-_146528750 1.61 ENST00000483300.5
phospholipid scramblase 1
chr14_-_23352872 1.59 ENST00000397267.5
solute carrier family 22 member 17
chr1_+_75786246 1.57 ENST00000319942.8
Rab geranylgeranyltransferase subunit beta
chrX_+_106611930 1.56 ENST00000372544.6
ENST00000372548.9
RPA1 related single stranded DNA binding protein, X-linked
chr5_+_141968886 1.55 ENST00000347642.7
ring finger protein 14
chr15_-_63156774 1.55 ENST00000462430.5
ribosomal protein S27 like
chr7_+_140696665 1.54 ENST00000476279.5
ENST00000461457.1
ENST00000465506.5
NADH:ubiquinone oxidoreductase subunit B2
chr2_-_174598206 1.53 ENST00000392546.6
ENST00000436221.1
WAS/WASL interacting protein family member 1
chr3_-_197183963 1.52 ENST00000653795.1
discs large MAGUK scaffold protein 1
chr5_+_140848360 1.51 ENST00000532602.2
protocadherin alpha 9
chr6_+_292050 1.49 ENST00000344450.9
dual specificity phosphatase 22
chr3_-_197183806 1.47 ENST00000671246.1
ENST00000660553.1
discs large MAGUK scaffold protein 1
chr9_-_93453540 1.47 ENST00000375412.11
family with sequence similarity 120A opposite strand
chr5_+_136160986 1.43 ENST00000507637.1
SMAD family member 5
chr7_+_140696956 1.42 ENST00000460088.5
ENST00000472695.5
NADH:ubiquinone oxidoreductase subunit B2
chr9_-_128190710 1.42 ENST00000415526.5
ENST00000393608.5
ENST00000277465.8
CDKN1A interacting zinc finger protein 1
chr16_-_4846196 1.42 ENST00000589389.5
glyoxylate reductase 1 homolog
chr11_+_118304721 1.38 ENST00000361763.9
CD3e molecule
chr4_+_8229170 1.37 ENST00000511002.6
SH3 domain and tetratricopeptide repeats 1
chr12_+_6789508 1.34 ENST00000011653.9
ENST00000541982.5
ENST00000539492.1
CD4 molecule
chr1_+_148748774 1.33 ENST00000322209.5
nudix hydrolase 4B
chr9_-_127937800 1.32 ENST00000373110.4
ENST00000314392.13
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
chr12_-_16608073 1.31 ENST00000441439.6
LIM domain only 3
chr15_+_65550819 1.25 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr3_+_12557050 1.19 ENST00000411987.5
ENST00000170447.12
ENST00000448482.1
ENST00000677142.1
makorin ring finger protein 2
chr12_-_16608183 1.17 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr2_-_182242031 1.15 ENST00000358139.6
phosphodiesterase 1A
chr17_-_48944772 1.08 ENST00000290330.7
ENST00000502492.6
SNF8 subunit of ESCRT-II
chr11_-_57427078 1.01 ENST00000528187.5
ENST00000524863.5
ENST00000533051.5
ENST00000529494.5
ENST00000395124.6
ENST00000533524.5
ENST00000533245.5
ENST00000530316.5
solute carrier family 43 member 3
chr3_+_113532508 1.01 ENST00000264852.9
SID1 transmembrane family member 1
chr2_+_201129826 0.99 ENST00000457277.5
CASP8 and FADD like apoptosis regulator
chr1_+_103655760 0.98 ENST00000370083.9
amylase alpha 1A
chr19_+_45039509 0.98 ENST00000544944.6
CLK4 associating serine/arginine rich protein
chr2_-_162152239 0.96 ENST00000418842.7
glucagon
chr11_+_118304881 0.96 ENST00000528600.1
CD3e molecule
chr19_+_21142024 0.95 ENST00000600692.5
ENST00000599296.5
ENST00000594425.5
ENST00000311048.11
zinc finger protein 431
chr5_-_177554545 0.93 ENST00000514747.6
family with sequence similarity 193 member B
chr17_+_41689862 0.93 ENST00000586699.1
eukaryotic translation initiation factor 1
chr2_-_182522703 0.91 ENST00000410103.1
phosphodiesterase 1A
chr6_-_52994248 0.90 ENST00000457564.1
ENST00000370960.5
glutathione S-transferase alpha 4
chr19_-_50968966 0.90 ENST00000376851.7
kallikrein related peptidase 6
chr4_+_153257339 0.89 ENST00000676374.1
ENST00000676196.1
ENST00000674935.1
ENST00000674769.1
ENST00000674896.1
ENST00000676191.1
ENST00000675312.1
ENST00000675456.1
ENST00000674847.1
ENST00000675977.1
ENST00000676264.1
ENST00000674726.1
ENST00000676252.1
ENST00000674730.1
ENST00000675738.1
ENST00000482578.3
tripartite motif containing 2
chr7_-_38363476 0.89 ENST00000426402.2
T cell receptor gamma variable 2
chr11_-_72112068 0.87 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
anaphase promoting complex subunit 15
chr2_-_97094882 0.82 ENST00000414820.6
ENST00000272610.3
fumarylacetoacetate hydrolase domain containing 2B
chr12_+_4590075 0.82 ENST00000540757.6
dual specificity tyrosine phosphorylation regulated kinase 4
chr2_+_54115437 0.78 ENST00000303536.8
ENST00000394666.7
acylphosphatase 2
chr10_-_59753444 0.78 ENST00000594536.5
ENST00000414264.6
myoregulin
chr3_-_197573323 0.77 ENST00000358186.6
ENST00000431056.5
3-hydroxybutyrate dehydrogenase 1
chr7_-_22193728 0.74 ENST00000620335.4
Rap guanine nucleotide exchange factor 5
chr16_+_11965234 0.72 ENST00000562385.1
TNF receptor superfamily member 17
chr2_-_79086847 0.69 ENST00000454188.5
regenerating family member 1 beta
chr1_-_205121986 0.67 ENST00000367164.1
RB binding protein 5, histone lysine methyltransferase complex subunit
chr16_-_370514 0.64 ENST00000199706.13
mitochondrial ribosomal protein L28
chr5_-_131796965 0.64 ENST00000514667.1
ENST00000511848.1
ENST00000510461.6
novel protein
folliculin interacting protein 1
chr1_+_6034980 0.63 ENST00000378092.6
ENST00000472700.7
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr1_-_103696209 0.63 ENST00000330330.10
amylase alpha 1B
chr16_-_18900044 0.63 ENST00000565224.5
ENST00000330588.4
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr1_+_197268204 0.61 ENST00000535699.5
ENST00000538660.5
crumbs cell polarity complex component 1
chr1_+_186375813 0.58 ENST00000419367.8
ENST00000287859.11
ENST00000367470.8
odr-4 GPCR localization factor homolog
chr18_-_50287570 0.54 ENST00000586837.1
ENST00000412036.6
ENST00000589940.5
ENST00000587396.1
ENST00000591474.5
ENST00000285106.11
CXXC finger protein 1
chr2_+_89947508 0.53 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr5_-_59430600 0.53 ENST00000636120.1
phosphodiesterase 4D
chr16_-_30894264 0.52 ENST00000380317.8
BAF chromatin remodeling complex subunit BCL7C
chr18_-_50287816 0.50 ENST00000589548.6
ENST00000673786.1
CXXC finger protein 1
chr6_-_31680377 0.50 ENST00000383237.4
lymphocyte antigen 6 family member G5C
chr10_-_95656643 0.48 ENST00000371221.3
ENST00000371224.7
aldehyde dehydrogenase 18 family member A1
chr15_+_90875688 0.46 ENST00000681865.1
furin, paired basic amino acid cleaving enzyme
chr2_+_209580024 0.46 ENST00000392194.5
microtubule associated protein 2
chr9_-_21217311 0.42 ENST00000380216.1
interferon alpha 16
chr11_-_89063631 0.42 ENST00000455756.6
glutamate metabotropic receptor 5
chr18_+_13277351 0.42 ENST00000679091.1
low density lipoprotein receptor class A domain containing 4
chr1_-_23980308 0.41 ENST00000374452.9
ENST00000492112.3
ENST00000343255.9
ENST00000344989.10
serine and arginine rich splicing factor 10
chr19_+_15793951 0.41 ENST00000308940.8
olfactory receptor family 10 subfamily H member 5
chr6_+_135181361 0.40 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chr18_+_34593312 0.40 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr9_-_129642094 0.40 ENST00000277459.8
ENST00000277458.5
ENST00000450050.6
ankyrin repeat and SOCS box containing 6
chr4_+_143433491 0.37 ENST00000512843.1
GRB2 associated binding protein 1
chr11_-_111871271 0.37 ENST00000398006.6
ALG9 alpha-1,2-mannosyltransferase
chr16_+_14632906 0.37 ENST00000563971.5
ENST00000562442.5
ENST00000261658.7
bifunctional apoptosis regulator
chr2_+_201129483 0.35 ENST00000440180.5
CASP8 and FADD like apoptosis regulator
chr4_-_88823306 0.34 ENST00000395002.6
family with sequence similarity 13 member A
chr16_+_11965193 0.34 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.5 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
1.6 9.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.4 4.1 GO:0009106 lipoate metabolic process(GO:0009106)
1.3 3.9 GO:0018094 protein polyglycylation(GO:0018094)
1.1 3.4 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
1.0 6.1 GO:0038016 insulin receptor internalization(GO:0038016)
1.0 2.9 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.9 3.7 GO:0042631 cellular response to water deprivation(GO:0042631)
0.9 2.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.9 3.4 GO:0099558 maintenance of synapse structure(GO:0099558)
0.9 8.5 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.8 4.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.7 2.9 GO:0022614 membrane to membrane docking(GO:0022614)
0.7 2.7 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.7 3.3 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.6 3.9 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.6 9.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.6 4.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.6 1.8 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.6 6.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.6 2.3 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.6 5.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.6 2.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031) mast cell differentiation(GO:0060374)
0.6 5.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 3.9 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.5 5.3 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.4 3.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.4 2.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.4 6.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.4 1.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.4 5.3 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.4 2.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.3 4.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 4.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 2.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.3 2.7 GO:0071569 protein ufmylation(GO:0071569)
0.3 1.6 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 4.4 GO:1900364 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) negative regulation of mRNA polyadenylation(GO:1900364)
0.3 5.6 GO:0008228 opsonization(GO:0008228)
0.3 4.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 1.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.3 6.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 3.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 1.7 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 1.4 GO:0001880 Mullerian duct regression(GO:0001880)
0.2 1.6 GO:0070560 protein secretion by platelet(GO:0070560)
0.2 1.3 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.2 6.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.2 0.4 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2 1.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.2 0.8 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 2.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 2.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 1.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 6.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.4 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 5.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 2.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.8 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 2.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.5 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 2.8 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 2.0 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 10.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 2.0 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.0 GO:0033227 dsRNA transport(GO:0033227)
0.1 2.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 3.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.5 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.9 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 4.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 3.6 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.1 2.8 GO:0010447 response to acidic pH(GO:0010447)
0.1 2.8 GO:0019054 NLS-bearing protein import into nucleus(GO:0006607) modulation by virus of host process(GO:0019054)
0.1 5.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 3.6 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.1 1.6 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 1.1 GO:0016540 protein autoprocessing(GO:0016540)
0.1 2.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 4.6 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 5.7 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.9 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 3.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 2.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 4.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 3.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.6 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 3.9 GO:0045576 mast cell activation(GO:0045576)
0.0 4.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 2.9 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.9 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.4 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 1.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 1.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 4.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 1.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 5.2 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0043159 acrosomal matrix(GO:0043159)
1.4 4.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.2 3.6 GO:0034515 proteasome storage granule(GO:0034515)
1.0 9.7 GO:0045180 basal cortex(GO:0045180)
0.9 2.7 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.9 4.4 GO:0036398 TCR signalosome(GO:0036398)
0.6 4.4 GO:0032021 NELF complex(GO:0032021)
0.6 5.1 GO:0044754 autolysosome(GO:0044754)
0.6 6.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.4 1.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.4 14.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4 1.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.4 2.7 GO:1990130 Iml1 complex(GO:1990130)
0.3 4.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 6.6 GO:0097342 ripoptosome(GO:0097342)
0.3 5.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 5.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 3.4 GO:0035253 ciliary rootlet(GO:0035253)
0.2 3.4 GO:0043083 synaptic cleft(GO:0043083)
0.2 3.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 3.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 5.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 7.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 5.3 GO:0097228 sperm principal piece(GO:0097228)
0.2 2.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 17.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 10.0 GO:0045171 intercellular bridge(GO:0045171)
0.1 3.9 GO:0030904 retromer complex(GO:0030904)
0.1 2.0 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 5.6 GO:0031430 M band(GO:0031430)
0.1 6.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.4 GO:0000786 nucleosome(GO:0000786)
0.1 13.0 GO:0043204 perikaryon(GO:0043204)
0.1 1.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 2.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 5.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 14.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 3.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.1 GO:0036452 ESCRT complex(GO:0036452)
0.0 4.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 2.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 2.8 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 1.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 8.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.5 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
1.7 8.5 GO:0042610 CD8 receptor binding(GO:0042610)
1.5 6.1 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
1.3 3.9 GO:0070735 protein-glycine ligase activity(GO:0070735)
1.1 3.4 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
1.0 2.9 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.9 2.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.8 6.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.6 3.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.6 5.3 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 8.2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.5 3.9 GO:0023029 MHC class Ib protein binding(GO:0023029) inhibitory MHC class I receptor activity(GO:0032396)
0.5 1.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.5 5.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.4 2.7 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.4 1.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.4 3.2 GO:0050733 RS domain binding(GO:0050733)
0.4 9.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 5.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 1.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 2.0 GO:0004359 glutaminase activity(GO:0004359)
0.3 1.7 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.3 1.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.3 1.6 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.3 5.3 GO:0097016 L27 domain binding(GO:0097016)
0.3 2.3 GO:0042608 T cell receptor binding(GO:0042608)
0.3 4.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 2.0 GO:0048039 ubiquinone binding(GO:0048039)
0.3 2.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 0.8 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 0.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 1.8 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.2 3.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 6.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 2.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 3.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 2.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.3 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.2 1.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 3.8 GO:0000339 RNA cap binding(GO:0000339)
0.1 2.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 5.1 GO:0001671 ATPase activator activity(GO:0001671)
0.1 4.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 5.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 7.2 GO:0030507 spectrin binding(GO:0030507)
0.1 1.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 4.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 3.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 5.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 3.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 6.6 GO:0050681 androgen receptor binding(GO:0050681)
0.1 10.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 2.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.5 GO:0008494 translation activator activity(GO:0008494)
0.1 1.5 GO:0005522 profilin binding(GO:0005522)
0.1 2.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 3.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 6.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 7.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.4 GO:0089720 caspase binding(GO:0089720)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 3.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 2.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 4.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 12.1 GO:0003682 chromatin binding(GO:0003682)
0.0 0.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 4.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 3.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 12.9 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 6.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 4.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 2.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 12.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 4.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 7.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 2.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 7.4 PID CDC42 PATHWAY CDC42 signaling events
0.1 2.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 1.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 5.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 4.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 1.0 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.3 3.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 4.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 14.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 1.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 6.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 8.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 3.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 5.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 8.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 5.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 2.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.7 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 7.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 3.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 3.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 6.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 2.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 5.7 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 1.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 2.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 2.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 4.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 5.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 11.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 5.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 3.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 3.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 3.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels