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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PAX3

Z-value: 3.33

Motif logo

Transcription factors associated with PAX3

Gene Symbol Gene ID Gene Info
ENSG00000135903.20 PAX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX3hg38_v1_chr2_-_222298808_2222988950.358.7e-08Click!

Activity profile of PAX3 motif

Sorted Z-values of PAX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_+_38561530 28.23 ENST00000378482.7
ENST00000286824.6
tetraspanin 7
chr22_-_43862480 19.09 ENST00000330884.9
sulfotransferase family 4A member 1
chr11_+_73647549 18.92 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr1_+_50048014 14.97 ENST00000448907.7
ELAV like RNA binding protein 4
chr15_+_99251362 14.61 ENST00000558879.5
ENST00000301981.8
ENST00000447360.6
ENST00000558172.5
ENST00000561276.5
ENST00000331450.9
leucine rich repeat containing 28
chr7_-_103989516 12.23 ENST00000343529.9
ENST00000424685.3
reelin
chr19_-_34677157 12.15 ENST00000601241.6
secretoglobin family 2B member 2
chr1_-_183418364 12.13 ENST00000287713.7
nicotinamide nucleotide adenylyltransferase 2
chr16_-_18358582 10.85 ENST00000327792.6
nuclear pore complex interacting protein family, member A9
chr18_+_26226472 10.45 ENST00000578121.5
TATA-box binding protein associated factor 4b
chr19_+_36916298 10.03 ENST00000427117.5
ENST00000333987.12
ENST00000587130.5
ENST00000415168.5
ENST00000444991.5
zinc finger protein 568
chr4_-_86357722 9.91 ENST00000641341.1
ENST00000642038.1
ENST00000641116.1
ENST00000641767.1
ENST00000639242.1
ENST00000638313.1
mitogen-activated protein kinase 10
chr4_+_8580387 9.81 ENST00000382487.5
G protein-coupled receptor 78
chr1_+_99264275 9.64 ENST00000457765.6
phospholipid phosphatase related 4
chr17_-_69150062 9.60 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr16_+_16350098 9.54 ENST00000331436.6
novel member of the nuclear pore complex interacting protein NPIP gene family
chr18_+_26226417 8.82 ENST00000269142.10
TATA-box binding protein associated factor 4b
chr9_-_89178810 8.74 ENST00000375835.9
SHC adaptor protein 3
chr8_+_116938180 8.37 ENST00000378279.4
alanine and arginine rich domain containing protein
chr4_+_155758990 8.16 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
guanylate cyclase 1 soluble subunit beta 1
chr1_+_35930712 8.06 ENST00000324350.9
argonaute RISC catalytic component 3
chr16_-_18375069 7.95 ENST00000545114.5
nuclear pore complex interacting protein family, member A9
chr11_+_123902167 7.71 ENST00000641687.1
olfactory receptor family 8 subfamily D member 4
chr1_+_84164370 7.52 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
protein kinase cAMP-activated catalytic subunit beta
chr14_+_22495890 7.02 ENST00000390494.1
T cell receptor alpha joining 43
chr2_-_44361485 7.02 ENST00000438314.1
ENST00000409411.6
ENST00000409936.5
prolyl endopeptidase like
chr15_-_52569126 6.93 ENST00000569723.5
ENST00000567669.5
ENST00000569281.6
ENST00000563566.5
ENST00000567830.1
cAMP regulated phosphoprotein 19
chr16_-_21837770 6.86 ENST00000537951.1
nuclear pore complex interacting protein family member B4
chr2_-_44361555 6.75 ENST00000409957.5
prolyl endopeptidase like
chr16_-_29485859 6.67 ENST00000458643.3
nuclear pore complex interacting protein family member B12
chr15_+_51681483 6.29 ENST00000542355.6
ENST00000220478.8
ENST00000558709.1
secretogranin III
chr19_+_52190006 6.06 ENST00000454220.6
ENST00000322088.11
ENST00000477989.1
ENST00000628959.1
protein phosphatase 2 scaffold subunit Aalpha
chr2_-_44361754 6.00 ENST00000409272.5
ENST00000410081.5
ENST00000541738.5
prolyl endopeptidase like
chr14_+_24114627 5.40 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr19_-_2783241 5.40 ENST00000676943.1
ENST00000589251.5
ENST00000221566.7
ENST00000676984.1
small glutamine rich tetratricopeptide repeat containing alpha
chr15_-_34437769 5.36 ENST00000359187.5
golgin A8 family member A
chr8_-_70071226 5.29 ENST00000276594.3
PR/SET domain 14
chr14_-_24114913 5.18 ENST00000561028.6
ENST00000558280.1
neural retina leucine zipper
chr16_-_21405319 5.17 ENST00000542817.1
nuclear pore complex interacting protein family member B3
chr8_-_30912998 5.09 ENST00000643185.2
testis expressed 15, meiosis and synapsis associated
chrX_-_104076194 4.85 ENST00000620307.4
ENST00000598087.3
thymosin beta 15B
chr19_-_2783308 4.84 ENST00000677562.1
ENST00000677754.1
small glutamine rich tetratricopeptide repeat containing alpha
chr7_+_100219236 4.79 ENST00000317271.2
PVR related immunoglobulin domain containing
chr6_+_14117764 4.66 ENST00000379153.4
CD83 molecule
chr6_+_163414637 4.66 ENST00000453779.6
ENST00000275262.11
ENST00000392127.6
QKI, KH domain containing RNA binding
chr18_-_57803307 4.55 ENST00000648908.2
ATPase phospholipid transporting 8B1
chr15_-_52568960 4.46 ENST00000564163.5
ENST00000249822.9
cAMP regulated phosphoprotein 19
chrX_-_49073989 4.42 ENST00000376386.3
ENST00000553851.3
PRA1 domain family member 2
chr7_+_29479712 4.40 ENST00000412711.6
chimerin 2
chr10_-_102419693 4.39 ENST00000611678.4
pleckstrin and Sec7 domain containing
chr12_+_112125531 4.14 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr10_+_94402486 4.13 ENST00000225235.5
TBC1 domain family member 12
chrX_+_71144818 4.12 ENST00000536169.5
ENST00000358741.4
ENST00000395855.6
ENST00000374051.7
neuroligin 3
chr7_+_142384328 3.98 ENST00000390361.3
T cell receptor beta variable 7-3
chr9_+_101398841 3.98 ENST00000339664.7
ENST00000374861.7
ENST00000259395.4
ENST00000615466.1
zinc finger protein 189
chr3_+_179322984 3.93 ENST00000496856.6
ENST00000491818.5
zinc finger protein 639
chr10_-_124744280 3.89 ENST00000337318.8
family with sequence similarity 53 member B
chr19_+_34677639 3.79 ENST00000627982.2
ENST00000613363.4
ENST00000502743.5
ENST00000509528.5
ENST00000506901.5
ENST00000457781.6
ENST00000505163.5
ENST00000505242.6
ENST00000423823.6
ENST00000507959.5
ENST00000446502.6
zinc finger protein 302
chr16_-_71489276 3.74 ENST00000564230.5
ENST00000565637.5
ENST00000288177.10
zinc finger protein 19
chr9_-_21202205 3.69 ENST00000239347.3
interferon alpha 7
chr22_+_18110802 3.68 ENST00000330423.8
tubulin alpha 8
chr19_+_34677723 3.67 ENST00000505365.2
zinc finger protein 302
chr17_-_3557798 3.65 ENST00000301365.8
ENST00000572519.1
ENST00000576742.6
transient receptor potential cation channel subfamily V member 3
chr4_+_112145445 3.65 ENST00000309733.6
family with sequence similarity 241 member A
chr2_+_170178136 3.54 ENST00000409044.7
ENST00000408978.9
myosin IIIB
chr15_+_90265634 3.52 ENST00000379095.5
neugrin, neurite outgrowth associated
chr2_-_113756604 3.45 ENST00000409342.1
solute carrier family 35 member F5
chr1_-_51878799 3.38 ENST00000354831.11
ENST00000544028.5
nardilysin convertase
chr9_-_70414657 3.35 ENST00000377126.4
Kruppel like factor 9
chr9_-_35650902 3.28 ENST00000259608.8
ENST00000618781.1
signaling threshold regulating transmembrane adaptor 1
chr5_-_181261078 3.27 ENST00000611618.1
tripartite motif containing 52
chrY_-_6911752 3.23 ENST00000651267.2
amelogenin Y-linked
chrX_+_37990773 3.17 ENST00000341016.5
H2A.P histone
chr2_-_216860042 3.14 ENST00000236979.2
transition protein 1
chr1_+_171314171 3.13 ENST00000367749.4
flavin containing dimethylaniline monoxygenase 4
chr12_-_53200443 3.13 ENST00000550743.6
integrin subunit beta 7
chr16_+_27203480 3.12 ENST00000286096.9
lysine demethylase 8
chr21_-_37267511 3.11 ENST00000398998.1
VPS26 endosomal protein sorting factor C
chr19_+_53538128 3.09 ENST00000511154.5
ENST00000449416.6
zinc finger protein 331
chr12_+_10307818 3.09 ENST00000350274.9
ENST00000336164.9
killer cell lectin like receptor D1
chr18_-_62186970 2.99 ENST00000639902.1
ENST00000639174.1
ENST00000638167.1
ENST00000639758.1
ENST00000638183.1
ENST00000638591.1
ENST00000589720.6
ENST00000639912.1
ENST00000639342.1
ENST00000640540.1
ENST00000638435.1
ENST00000589339.6
ENST00000586566.2
ENST00000585458.2
ENST00000357637.10
ENST00000400334.7
ENST00000638329.1
ENST00000585923.6
ENST00000590765.5
ENST00000640252.2
ENST00000640876.1
ENST00000638977.1
ENST00000638369.1
ENST00000588571.6
ENST00000640145.1
ENST00000638936.1
ENST00000585344.6
phosphatidylinositol glycan anchor biosynthesis class N
chr9_-_97922487 2.98 ENST00000455506.1
ENST00000375117.8
ENST00000375119.8
ENST00000611338.4
tRNA methyltransferase O
chr5_+_50665899 2.95 ENST00000505697.6
poly(ADP-ribose) polymerase family member 8
chr1_-_51331315 2.93 ENST00000262676.9
tetratricopeptide repeat domain 39A
chr9_-_21368962 2.80 ENST00000610660.1
interferon alpha 13
chr12_+_8989612 2.74 ENST00000266551.8
killer cell lectin like receptor G1
chr6_+_127266832 2.62 ENST00000356799.6
ENST00000368314.6
ring finger protein 146
chr6_-_69699124 2.57 ENST00000651675.1
LMBR1 domain containing 1
chr16_-_74985070 2.46 ENST00000616369.4
ENST00000262144.11
WD repeat domain 59
chr1_-_203351115 2.40 ENST00000354955.5
fibromodulin
chr15_-_52569197 2.38 ENST00000563277.5
ENST00000566423.5
cAMP regulated phosphoprotein 19
chr6_+_127266875 2.31 ENST00000610162.5
ENST00000608991.5
ENST00000610153.1
ring finger protein 146
chr14_+_24115299 2.31 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr6_+_35259703 2.29 ENST00000373953.8
ENST00000339411.5
zinc finger protein 76
chr11_+_112167366 2.26 ENST00000530752.5
ENST00000280358.5
testis expressed 12
chr20_-_25585517 2.25 ENST00000422516.5
ENST00000278886.11
ninein like
chr12_+_8989535 2.25 ENST00000356986.8
killer cell lectin like receptor G1
chr5_+_141370236 2.18 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr6_-_31972123 2.15 ENST00000337523.10
decapping exoribonuclease
chr1_+_1287109 2.10 ENST00000379099.3
sodium channel epithelial 1 subunit delta
chr2_+_44361897 2.06 ENST00000378494.8
ENST00000402247.5
ENST00000407131.5
ENST00000403853.7
calmodulin-lysine N-methyltransferase
chr10_+_89327989 2.04 ENST00000679923.1
ENST00000680085.1
ENST00000371818.9
ENST00000680779.1
interferon induced protein with tetratricopeptide repeats 3
chr2_+_167868948 2.02 ENST00000392690.3
beta-1,3-galactosyltransferase 1
chr10_+_89327977 2.01 ENST00000681277.1
interferon induced protein with tetratricopeptide repeats 3
chr14_-_59465327 1.90 ENST00000395116.1
G protein-coupled receptor 135
chr3_-_50345665 1.86 ENST00000442887.1
ENST00000231749.8
ENST00000360165.7
zinc finger MYND-type containing 10
chr19_+_54497879 1.79 ENST00000412608.5
ENST00000610651.1
leukocyte associated immunoglobulin like receptor 2
chr2_-_68252482 1.79 ENST00000234310.8
protein phosphatase 3 regulatory subunit B, alpha
chr10_+_116545907 1.75 ENST00000369221.2
pancreatic lipase
chr14_+_69191475 1.71 ENST00000409018.7
ENST00000409014.5
ENST00000409675.5
exonuclease 3'-5' domain containing 2
chr3_-_119660580 1.71 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
popeye domain containing 2
chrX_-_119565362 1.67 ENST00000320339.8
ENST00000536133.2
ENST00000644802.2
STING1 ER exit protein 1
chr19_+_51225059 1.65 ENST00000436584.6
ENST00000421133.6
ENST00000262262.5
ENST00000391796.7
CD33 molecule
chr18_+_58362467 1.63 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr12_+_10307950 1.56 ENST00000543420.5
ENST00000543777.5
killer cell lectin like receptor D1
chr2_-_218659592 1.54 ENST00000411696.7
zinc finger protein 142
chr1_-_51878711 1.52 ENST00000352171.12
nardilysin convertase
chr20_-_17531366 1.47 ENST00000377873.8
beaded filament structural protein 1
chr1_+_6034980 1.40 ENST00000378092.6
ENST00000472700.7
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr2_-_182522556 1.40 ENST00000435564.5
phosphodiesterase 1A
chr1_-_13198130 1.39 ENST00000638454.1
PRAME family member 13
chr17_-_61591192 1.29 ENST00000521764.3
nascent polypeptide associated complex subunit alpha 2
chr1_+_145719483 1.28 ENST00000369288.7
CD160 molecule
chr5_-_157652432 1.24 ENST00000265007.11
SRY-box transcription factor 30
chr19_-_40090860 1.23 ENST00000599972.1
ENST00000450241.6
ENST00000595687.6
ENST00000340963.9
zinc finger protein 780A
chr2_-_218659468 1.21 ENST00000450560.1
ENST00000449707.5
ENST00000440934.2
zinc finger protein 142
chr2_-_182522703 1.15 ENST00000410103.1
phosphodiesterase 1A
chrY_+_22992344 1.14 ENST00000382585.2
basic charge Y-linked 2
chr4_-_140568958 1.12 ENST00000262999.4
uncoupling protein 1
chr7_+_107660819 1.10 ENST00000644269.2
solute carrier family 26 member 4
chr3_+_49689531 1.08 ENST00000432042.5
ENST00000454491.5
ENST00000327697.11
ring finger protein 123
chr1_-_101025763 1.02 ENST00000342173.11
ENST00000488176.1
ENST00000370109.8
diphthamide biosynthesis 5
chr1_+_145719468 1.01 ENST00000616463.1
CD160 molecule
chr7_+_142598016 0.98 ENST00000620773.1
T cell receptor beta variable 16
chr9_-_21217311 0.96 ENST00000380216.1
interferon alpha 16
chr19_-_20565769 0.91 ENST00000427401.9
zinc finger protein 737
chr19_-_40090921 0.88 ENST00000595508.1
ENST00000414720.6
ENST00000455521.5
ENST00000595773.5
ENST00000683561.1
novel transcript
zinc finger protein 780A
chr9_-_36401198 0.85 ENST00000377885.6
ring finger protein 38
chr15_-_52191387 0.83 ENST00000261837.12
G protein subunit beta 5
chr9_+_128787243 0.83 ENST00000372648.10
TBC1 domain family member 13
chrX_+_30247139 0.83 ENST00000397548.4
MAGE family member B1
chr3_+_50155305 0.82 ENST00000002829.8
ENST00000426511.5
semaphorin 3F
chr10_-_100529854 0.81 ENST00000370320.4
ENST00000299166.9
ENST00000370322.5
NADH:ubiquinone oxidoreductase subunit B8
chr22_+_38705922 0.80 ENST00000216044.10
GTP binding protein 1
chr3_+_38265802 0.73 ENST00000311856.9
solute carrier family 22 member 13
chr4_-_170003738 0.72 ENST00000502832.1
ENST00000393704.3
microfibril associated protein 3 like
chr14_-_64338096 0.72 ENST00000554572.5
ENST00000358599.9
estrogen receptor 2
chr21_-_37267300 0.68 ENST00000309117.11
ENST00000476950.5
ENST00000399001.5
VPS26 endosomal protein sorting factor C
chrX_-_15854791 0.66 ENST00000545766.7
ENST00000380291.5
ENST00000672987.1
ENST00000329235.6
adaptor related protein complex 1 subunit sigma 2
chrX_+_103628692 0.56 ENST00000372626.7
transcription elongation factor A like 1
chrX_+_136148440 0.49 ENST00000627383.2
ENST00000630084.2
four and a half LIM domains 1
chr9_-_13175824 0.46 ENST00000545857.5
multiple PDZ domain crumbs cell polarity complex component
chr6_+_133241318 0.44 ENST00000430974.6
ENST00000355286.12
ENST00000355167.8
ENST00000431403.3
EYA transcriptional coactivator and phosphatase 4
chr2_-_182242031 0.42 ENST00000358139.6
phosphodiesterase 1A
chr12_-_10409757 0.36 ENST00000309384.2
killer cell lectin like receptor C4
chr3_-_54967088 0.31 ENST00000493075.1
leucine rich repeats and transmembrane domains 1
chrX_+_1615049 0.26 ENST00000381241.9
acetylserotonin O-methyltransferase
chr21_-_28992947 0.20 ENST00000389194.7
ENST00000389195.7
ENST00000614971.4
listerin E3 ubiquitin protein ligase 1
chr11_+_31369834 0.17 ENST00000465995.6
DnaJ heat shock protein family (Hsp40) member C24
chr2_+_73385811 0.14 ENST00000613296.6
ENST00000614410.4
ALMS1 centrosome and basal body associated protein
chr6_+_28525986 0.14 ENST00000469384.1
glutathione peroxidase 5
chr9_+_128787331 0.10 ENST00000223865.8
TBC1 domain family member 13
chr6_+_133241566 0.04 ENST00000531901.5
EYA transcriptional coactivator and phosphatase 4
chr4_-_167234426 0.03 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chrX_+_43656289 0.02 ENST00000338702.4
monoamine oxidase A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
3.0 12.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
2.6 10.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
2.0 6.1 GO:0051232 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
1.4 4.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.3 8.1 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
1.3 7.5 GO:0097338 response to clozapine(GO:0097338)
1.1 13.8 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
1.1 5.3 GO:1902093 positive regulation of sperm motility(GO:1902093)
1.0 5.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.8 2.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.8 3.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.8 4.6 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.7 9.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.6 19.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.6 3.7 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.5 4.7 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.4 3.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 2.6 GO:0038016 insulin receptor internalization(GO:0038016)
0.4 3.4 GO:0051414 response to cortisol(GO:0051414)
0.4 19.8 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.4 19.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.3 21.0 GO:0007602 phototransduction(GO:0007602)
0.3 4.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.3 1.1 GO:0019532 oxalate transport(GO:0019532)
0.3 4.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 2.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 3.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.2 4.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 3.6 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 5.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.2 9.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.2 1.4 GO:0070995 NADPH oxidation(GO:0070995)
0.2 3.1 GO:0042737 drug catabolic process(GO:0042737)
0.1 3.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 4.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 2.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 1.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 3.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.9 GO:0036158 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.1 3.2 GO:0034505 tooth mineralization(GO:0034505)
0.1 3.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.2 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 0.8 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 4.4 GO:0015813 L-glutamate transport(GO:0015813)
0.1 1.1 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 3.9 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 1.5 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.8 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 9.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 0.7 GO:0015747 urate transport(GO:0015747)
0.1 8.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 7.6 GO:0006968 cellular defense response(GO:0006968)
0.1 0.3 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 4.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 2.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 3.3 GO:0043029 T cell homeostasis(GO:0043029)
0.1 4.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.8 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 1.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 4.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.8 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 2.0 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.7 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 8.4 GO:0030324 lung development(GO:0030324)
0.0 0.9 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 7.9 GO:0006869 lipid transport(GO:0006869)
0.0 3.7 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.8 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 3.5 GO:0007601 visual perception(GO:0007601)
0.0 1.7 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 7.8 GO:0006397 mRNA processing(GO:0006397)
0.0 4.4 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.8 3.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.6 2.3 GO:0000801 central element(GO:0000801)
0.4 3.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 19.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.4 7.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 2.5 GO:0061700 GATOR2 complex(GO:0061700)
0.3 1.4 GO:1990031 pinceau fiber(GO:1990031)
0.3 1.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 7.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 1.8 GO:0005955 calcineurin complex(GO:0005955)
0.2 6.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 5.6 GO:0031526 brush border membrane(GO:0031526)
0.1 4.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 5.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 13.8 GO:0005770 late endosome(GO:0005770)
0.0 1.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 3.5 GO:0016459 myosin complex(GO:0016459)
0.0 14.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 57.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 70.9 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.9 GO:0036126 sperm flagellum(GO:0036126)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
3.0 12.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
1.5 10.2 GO:1904288 BAT3 complex binding(GO:1904288)
1.4 19.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.1 19.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.0 3.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.9 4.7 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.8 7.7 GO:0005549 odorant binding(GO:0005549)
0.8 9.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.7 3.0 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.7 19.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.7 4.9 GO:0048408 epidermal growth factor binding(GO:0048408)
0.6 9.6 GO:0042577 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.5 2.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.5 3.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5 7.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 3.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 3.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.4 15.0 GO:0017091 AU-rich element binding(GO:0017091)
0.4 5.7 GO:1901612 cardiolipin binding(GO:1901612)
0.3 5.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 8.1 GO:0035198 miRNA binding(GO:0035198)
0.3 2.6 GO:0015235 cobalamin transporter activity(GO:0015235)
0.3 13.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.3 4.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.3 1.7 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 1.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 4.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 3.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 2.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 2.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.8 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 2.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.7 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 3.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 8.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 1.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 6.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 3.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 9.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 1.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 2.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.9 GO:0043621 protein self-association(GO:0043621)
0.0 4.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 1.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 3.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 3.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 5.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 6.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 3.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 26.4 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 8.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 2.1 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 9.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 7.5 PID IL3 PATHWAY IL3-mediated signaling events
0.1 19.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 10.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 6.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 3.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 4.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 19.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 9.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 8.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 9.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 6.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.3 19.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 7.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 12.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 5.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 3.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 3.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 7.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 4.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 6.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 2.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 2.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 10.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 4.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels