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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PAX8

Z-value: 2.13

Motif logo

Transcription factors associated with PAX8

Gene Symbol Gene ID Gene Info
ENSG00000125618.18 PAX8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX8hg38_v1_chr2_-_113235443_1132355210.111.0e-01Click!

Activity profile of PAX8 motif

Sorted Z-values of PAX8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_+_136979042 14.80 ENST00000446677.2
prostaglandin D2 synthase
chr2_-_174847525 12.57 ENST00000295497.12
ENST00000652036.1
ENST00000444394.6
ENST00000650731.1
chimerin 1
chr2_-_174847765 12.26 ENST00000443238.6
chimerin 1
chr12_-_49900250 9.90 ENST00000552669.5
Fas apoptotic inhibitory molecule 2
chr19_+_35140022 9.85 ENST00000588081.5
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr2_+_17539964 9.71 ENST00000457525.5
visinin like 1
chr3_+_319683 9.62 ENST00000620033.4
cell adhesion molecule L1 like
chr22_-_43862480 9.22 ENST00000330884.9
sulfotransferase family 4A member 1
chr19_-_37210484 8.29 ENST00000527838.5
ENST00000591492.5
ENST00000532828.7
zinc finger protein 585B
chr6_+_36885944 7.45 ENST00000480824.7
chromosome 6 open reading frame 89
chr1_-_37692205 7.30 ENST00000477060.1
ENST00000491981.5
ENST00000488137.5
ENST00000619962.1
chromosome 1 open reading frame 109
chr19_+_9087061 6.93 ENST00000641627.1
olfactory receptor family 1 subfamily M member 1
chr1_-_184037695 6.47 ENST00000361927.9
ENST00000649786.1
collagen beta(1-O)galactosyltransferase 2
chr11_-_129192291 6.33 ENST00000682385.1
Rho GTPase activating protein 32
chr15_+_72118392 6.24 ENST00000340912.6
SUMO peptidase family member, NEDD8 specific
chr2_-_2326210 5.98 ENST00000647755.1
myelin transcription factor 1 like
chr4_+_155758990 5.89 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
guanylate cyclase 1 soluble subunit beta 1
chr11_-_129192198 5.76 ENST00000310343.13
Rho GTPase activating protein 32
chr8_+_22057857 5.66 ENST00000517305.4
ENST00000265800.9
ENST00000517418.5
dematin actin binding protein
chr2_+_172860038 5.32 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr11_-_8682619 4.93 ENST00000646038.2
tripartite motif containing 66
chr15_-_72118114 4.70 ENST00000356056.10
ENST00000569314.1
myosin IXA
chr4_-_46909206 4.70 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr18_-_23437927 4.59 ENST00000578520.5
ENST00000383233.8
transmembrane protein 241
chr11_+_123358416 4.51 ENST00000638157.1
GRAM domain containing 1B
chr9_+_135075422 4.49 ENST00000371799.8
ENST00000277415.15
olfactomedin 1
chr2_+_99181173 4.45 ENST00000338148.8
ENST00000409145.5
mitochondrial ribosomal protein L30
chr2_-_2326378 4.35 ENST00000647618.1
myelin transcription factor 1 like
chr5_+_140868945 4.27 ENST00000398640.7
protocadherin alpha 11
chr3_+_150546765 4.19 ENST00000406576.7
ENST00000460851.6
ENST00000482093.5
ENST00000273435.9
eukaryotic translation initiation factor 2A
chr4_+_153152163 4.13 ENST00000676423.1
ENST00000675745.1
ENST00000676348.1
ENST00000676408.1
ENST00000674874.1
ENST00000675315.1
ENST00000675518.1
tripartite motif containing 2
novel protein
chr6_+_160121859 4.12 ENST00000324965.8
ENST00000457470.6
solute carrier family 22 member 1
chr18_+_45825666 3.91 ENST00000389474.8
sialic acid binding Ig like lectin 15
chr7_+_76048036 3.78 ENST00000461263.2
ENST00000443006.5
ENST00000315758.10
malate dehydrogenase 2
chr22_-_50085414 3.75 ENST00000311597.10
modulator of VRAC current 1
chr6_+_160121809 3.65 ENST00000366963.9
solute carrier family 22 member 1
chr22_-_50085331 3.65 ENST00000395876.6
modulator of VRAC current 1
chr2_-_135530561 3.59 ENST00000536680.5
ENST00000401392.5
zinc finger RANBP2-type containing 3
chr19_-_52786742 3.50 ENST00000338230.3
ENST00000648973.1
zinc finger protein 600
chr12_+_133181409 3.44 ENST00000416488.5
ENST00000228289.9
ENST00000541211.6
ENST00000536435.7
ENST00000500625.7
ENST00000539248.6
ENST00000542711.6
ENST00000536899.6
ENST00000542986.6
ENST00000611984.4
ENST00000541975.2
zinc finger protein 268
chr18_-_55401751 3.44 ENST00000537856.7
transcription factor 4
chr7_-_99679987 3.40 ENST00000222982.8
ENST00000439761.3
ENST00000339843.6
cytochrome P450 family 3 subfamily A member 5
chr15_+_23565705 3.40 ENST00000568252.1
ENST00000649065.1
makorin ring finger protein 3
chr7_+_149838365 3.34 ENST00000460379.1
ENST00000223210.5
zinc finger protein 862
chr4_-_185956652 3.34 ENST00000355634.9
sorbin and SH3 domain containing 2
chrM_+_4467 3.31 ENST00000361453.3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr7_+_20615653 3.28 ENST00000404938.7
ATP binding cassette subfamily B member 5
chr19_-_3500664 3.21 ENST00000427575.6
deoxyhypusine hydroxylase
chr4_+_71339014 3.19 ENST00000340595.4
solute carrier family 4 member 4
chr2_+_79025678 3.16 ENST00000393897.6
regenerating family member 3 gamma
chr12_+_77830886 3.14 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr2_+_79025709 3.11 ENST00000409471.1
regenerating family member 3 gamma
chr2_+_79025696 3.06 ENST00000272324.10
regenerating family member 3 gamma
chr10_+_102152169 3.04 ENST00000405356.5
nucleolar and coiled-body phosphoprotein 1
chr19_-_3500625 2.98 ENST00000672935.1
deoxyhypusine hydroxylase
chr11_-_102530738 2.97 ENST00000260227.5
matrix metallopeptidase 7
chr8_-_52409743 2.96 ENST00000276480.11
ST18 C2H2C-type zinc finger transcription factor
chr5_-_88877967 2.91 ENST00000508610.5
ENST00000636294.1
myocyte enhancer factor 2C
chr10_+_102152380 2.91 ENST00000605788.6
ENST00000488254.6
ENST00000461421.5
ENST00000476468.5
ENST00000370007.5
nucleolar and coiled-body phosphoprotein 1
chr19_+_18683656 2.90 ENST00000338797.10
ENST00000321949.13
CREB regulated transcription coactivator 1
chr4_+_8580387 2.89 ENST00000382487.5
G protein-coupled receptor 78
chr10_+_133527355 2.89 ENST00000252945.8
ENST00000421586.5
ENST00000418356.1
cytochrome P450 family 2 subfamily E member 1
chr19_+_15737985 2.66 ENST00000641646.1
olfactory receptor family 10 subfamily H member 3
chr13_+_24764158 2.61 ENST00000255324.10
ENST00000255325.6
ring finger protein 17
chr17_-_8397815 2.58 ENST00000399398.2
ring finger protein 222
chr4_-_185956348 2.56 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr1_+_160739239 2.55 ENST00000368043.8
SLAM family member 7
chr1_+_171314171 2.47 ENST00000367749.4
flavin containing dimethylaniline monoxygenase 4
chr1_+_27773189 2.42 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr2_-_79086847 2.40 ENST00000454188.5
regenerating family member 1 beta
chr16_-_3256587 2.38 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV innate immuity regulator, pyrin
chr1_+_203765168 2.34 ENST00000367217.5
ENST00000442561.7
lymphocyte transmembrane adaptor 1
chr2_-_79159747 2.31 ENST00000409839.7
ENST00000305165.3
ENST00000393878.5
ENST00000490901.2
regenerating family member 3 alpha
chr19_+_41797147 2.26 ENST00000596544.1
CEA cell adhesion molecule 3
chr1_-_153057504 2.25 ENST00000392653.3
small proline rich protein 2A
chr4_+_74365136 2.22 ENST00000244869.3
epiregulin
chr19_+_51225059 2.22 ENST00000436584.6
ENST00000421133.6
ENST00000262262.5
ENST00000391796.7
CD33 molecule
chr4_+_118888829 2.15 ENST00000448416.6
ENST00000307142.9
ENST00000429713.7
synaptopodin 2
chrX_-_72239022 2.13 ENST00000373657.2
ENST00000334463.4
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr17_-_46579651 2.13 ENST00000573185.5
ENST00000570550.5
ENST00000445552.6
ENST00000329240.10
ENST00000622488.6
ENST00000336125.6
ADP ribosylation factor like GTPase 17A
chr3_-_16605416 2.12 ENST00000399444.7
deleted in azoospermia like
chr15_-_55498317 2.11 ENST00000568310.1
ENST00000565113.5
ENST00000448430.6
ENST00000457155.6
DNAAF4-CCPG1 readthrough (NMD candidate)
dynein axonemal assembly factor 4
chr1_-_182604379 2.11 ENST00000367558.6
regulator of G protein signaling 16
chr19_+_7920313 2.01 ENST00000221573.11
ENST00000595637.1
small nuclear RNA activating complex polypeptide 2
chr4_+_70734419 2.00 ENST00000502653.5
RUN and FYVE domain containing 3
chr3_-_49120887 1.94 ENST00000453664.5
ENST00000398888.6
ubiquitin specific peptidase 19
chr12_+_124993633 1.89 ENST00000341446.9
ENST00000671775.2
BRI3 binding protein
chr19_-_38812936 1.89 ENST00000307751.9
ENST00000594209.1
galectin 4
chr6_+_72212802 1.89 ENST00000401910.7
regulating synaptic membrane exocytosis 1
chr11_+_27055215 1.87 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr20_+_4171709 1.86 ENST00000379460.6
spermine oxidase
chr8_+_58411333 1.85 ENST00000399598.7
UBX domain protein 2B
chr2_+_27148997 1.84 ENST00000296096.6
transcription factor 23
chr21_-_26090035 1.82 ENST00000448850.5
amyloid beta precursor protein
chr1_-_153094521 1.80 ENST00000368750.8
small proline rich protein 2E
chr3_-_49120785 1.79 ENST00000417901.5
ENST00000306026.5
ENST00000434032.6
ubiquitin specific peptidase 19
chr6_+_72212887 1.76 ENST00000523963.5
regulating synaptic membrane exocytosis 1
chr20_-_3781440 1.76 ENST00000379756.3
sperm flagellar 1
chr10_-_20897288 1.75 ENST00000377122.9
nebulette
chr19_+_840991 1.74 ENST00000234347.10
proteinase 3
chr4_-_151760977 1.74 ENST00000512306.5
ENST00000508611.1
ENST00000515812.5
ENST00000263985.11
glutamyl-tRNA amidotransferase subunit B
chr2_-_178807415 1.72 ENST00000342992.10
ENST00000460472.6
ENST00000589042.5
ENST00000591111.5
ENST00000360870.10
titin
chr1_+_89524871 1.64 ENST00000639264.1
leucine rich repeat containing 8 VRAC subunit B
chr3_+_186717348 1.61 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
kininogen 1
chr22_+_20774092 1.61 ENST00000215727.10
serpin family D member 1
chr2_-_151734467 1.59 ENST00000397345.8
ENST00000427231.7
ENST00000409198.5
nebulin
chr17_-_46361718 1.58 ENST00000575960.5
ENST00000575698.5
ENST00000571246.5
ENST00000434041.6
ENST00000656849.1
ENST00000570618.5
ENST00000450673.4
ENST00000622877.4
ADP ribosylation factor like GTPase 17B
chr9_+_27109393 1.56 ENST00000406359.8
TEK receptor tyrosine kinase
chr6_-_44265541 1.54 ENST00000619360.6
NFKB inhibitor epsilon
chr6_-_142147122 1.54 ENST00000258042.2
neuromedin B receptor
chr17_+_7558258 1.53 ENST00000483039.5
ENST00000380535.8
ENST00000396542.5
TNF superfamily member 13
chrX_-_48356688 1.53 ENST00000298396.7
ENST00000376893.7
SSX family member 3
chr21_-_34511243 1.52 ENST00000399284.1
potassium voltage-gated channel subfamily E regulatory subunit 1
chr9_-_21228222 1.50 ENST00000413767.2
interferon alpha 17
chrX_-_33211540 1.47 ENST00000357033.9
dystrophin
chr8_+_123416735 1.46 ENST00000524254.5
N-terminal glutamine amidase 1
chr3_-_38794042 1.46 ENST00000643924.1
sodium voltage-gated channel alpha subunit 10
chr14_+_21978440 1.45 ENST00000390443.3
T cell receptor alpha variable 8-6
chr1_-_153541765 1.42 ENST00000368718.5
S100 calcium binding protein A5
chr17_+_7558712 1.42 ENST00000338784.9
ENST00000625791.2
TNF superfamily member 13
chr8_+_123416718 1.40 ENST00000523984.5
N-terminal glutamine amidase 1
chr3_-_114759115 1.39 ENST00000471418.5
zinc finger and BTB domain containing 20
chr19_-_44356664 1.39 ENST00000354340.9
ENST00000337401.8
ENST00000587909.1
zinc finger protein 112
chr15_-_73633310 1.38 ENST00000345330.9
neuroplastin
chr17_+_7558465 1.38 ENST00000349228.8
TNF superfamily member 13
chr19_+_17226662 1.36 ENST00000598068.5
occludin/ELL domain containing 1
chr7_+_7566866 1.35 ENST00000405785.5
ENST00000340080.9
ENST00000433635.1
meiosis regulator for oocyte development
chr9_+_121286586 1.35 ENST00000545652.6
gelsolin
chr8_+_123416766 1.34 ENST00000287387.7
ENST00000650311.1
ENST00000523356.1
N-terminal glutamine amidase 1
chr6_+_160702238 1.33 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chr1_-_27626229 1.33 ENST00000399173.5
FGR proto-oncogene, Src family tyrosine kinase
chr5_-_113434978 1.32 ENST00000390666.4
testis specific serine kinase 1B
chr1_+_86547070 1.31 ENST00000370563.3
chloride channel accessory 4
chr12_-_9208388 1.31 ENST00000261336.7
PZP alpha-2-macroglobulin like
chr7_+_92447426 1.30 ENST00000287957.5
GATA zinc finger domain containing 1
chr4_+_68815991 1.29 ENST00000265403.12
ENST00000458688.2
UDP glucuronosyltransferase family 2 member B10
chr19_+_16185380 1.27 ENST00000589852.5
ENST00000263384.12
ENST00000588367.5
ENST00000587351.1
family with sequence similarity 32 member A
chr6_-_46921926 1.25 ENST00000283296.12
adhesion G protein-coupled receptor F5
chr2_+_87748087 1.23 ENST00000359481.9
plasminogen like B2
chr5_+_70900669 1.21 ENST00000511162.1
ENST00000317633.14
ENST00000354833.7
ENST00000513436.6
ENST00000504458.1
small EDRK-rich factor 1A
chr8_-_7056729 1.21 ENST00000330590.4
defensin alpha 5
chr5_+_70025247 1.19 ENST00000380751.9
ENST00000380750.8
ENST00000503931.5
ENST00000506542.1
small EDRK-rich factor 1B
chr19_+_41796616 1.18 ENST00000344550.4
CEA cell adhesion molecule 3
chr1_+_40450053 1.17 ENST00000484445.5
ENST00000411995.6
ZFP69 zinc finger protein B
chr1_+_89524819 1.17 ENST00000439853.6
ENST00000330947.7
ENST00000449440.5
ENST00000640258.1
leucine rich repeat containing 8 VRAC subunit B
chr10_+_89332484 1.16 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
interferon induced protein with tetratricopeptide repeats 3
chr7_+_90245207 1.10 ENST00000497910.5
cilia and flagella associated protein 69
chr9_-_114074969 1.09 ENST00000466610.6
alpha-1-microglobulin/bikunin precursor
chr19_-_15934410 1.08 ENST00000326742.12
cytochrome P450 family 4 subfamily F member 11
chr2_-_87021844 1.04 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr1_-_169734064 0.99 ENST00000333360.12
selectin E
chr11_+_17260353 0.99 ENST00000530527.5
nucleobindin 2
chrX_+_152714586 0.98 ENST00000331220.6
ENST00000370293.6
ENST00000423993.5
ENST00000447530.5
ENST00000682532.1
ENST00000458057.5
ENST00000422085.5
ENST00000453150.5
ENST00000409560.1
MAGE family member A2B
chr4_-_79408198 0.98 ENST00000358842.5
glycerol kinase 2
chr6_+_167122742 0.95 ENST00000341935.9
ENST00000349984.6
C-C motif chemokine receptor 6
chr2_+_90209873 0.93 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr17_+_69414690 0.91 ENST00000590474.7
mitogen-activated protein kinase kinase 6
chr11_+_61229583 0.89 ENST00000544899.1
pepsinogen A4
chrX_-_153875847 0.89 ENST00000361699.8
ENST00000361981.7
L1 cell adhesion molecule
chr8_+_119067239 0.81 ENST00000332843.3
collectin subfamily member 10
chr5_+_140855882 0.80 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
protocadherin alpha 10
chr19_-_7702139 0.80 ENST00000346664.9
Fc fragment of IgE receptor II
chr6_+_27815010 0.79 ENST00000621112.2
H2B clustered histone 14
chr1_+_100352451 0.78 ENST00000361544.11
ENST00000370124.8
ENST00000336454.5
cell division cycle 14A
chr2_+_62673851 0.77 ENST00000405015.7
ENST00000413434.5
ENST00000426940.5
ENST00000449820.5
EH domain binding protein 1
chr17_+_7558774 0.77 ENST00000396545.4
TNF superfamily member 13
chr4_+_55853639 0.76 ENST00000381295.7
ENST00000346134.11
ENST00000349598.6
exocyst complex component 1
chr17_-_3595831 0.75 ENST00000399759.7
transient receptor potential cation channel subfamily V member 1
chr11_+_68903849 0.75 ENST00000675615.1
ENST00000255078.8
immunoglobulin mu DNA binding protein 2
chr2_-_218659592 0.73 ENST00000411696.7
zinc finger protein 142
chr19_-_7702124 0.73 ENST00000597921.6
Fc fragment of IgE receptor II
chr12_-_10098977 0.72 ENST00000315330.8
ENST00000457018.6
C-type lectin domain family 1 member A
chr14_+_77324557 0.71 ENST00000553586.5
ENST00000555583.1
glutathione S-transferase zeta 1
chr12_-_10420550 0.68 ENST00000381903.2
ENST00000396439.7
killer cell lectin like receptor C3
chr7_+_128672275 0.67 ENST00000684498.1
ENST00000641605.1
ENST00000682356.1
ENST00000477515.3
family with sequence similarity 71 member F2
chr21_-_42395943 0.67 ENST00000398405.5
transmembrane serine protease 3
chr15_-_74082550 0.66 ENST00000290438.3
golgin A6 family member A
chr9_+_128787331 0.65 ENST00000223865.8
TBC1 domain family member 13
chr17_+_7558296 0.61 ENST00000438470.5
ENST00000436057.5
TNF superfamily member 13
chr2_-_2326161 0.60 ENST00000649810.1
ENST00000648318.1
myelin transcription factor 1 like
chr15_+_89088417 0.60 ENST00000569550.5
ENST00000565066.5
ENST00000565973.5
ENST00000352732.10
abhydrolase domain containing 2, acylglycerol lipase
chr10_+_12349685 0.59 ENST00000378845.5
calcium/calmodulin dependent protein kinase ID
chr15_-_43493105 0.56 ENST00000382039.7
ENST00000450115.6
ENST00000382044.9
tumor protein p53 binding protein 1
chr7_+_95485934 0.55 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chr1_-_186680411 0.55 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr22_-_42070778 0.49 ENST00000396398.8
ENST00000403363.5
ENST00000402937.1
alpha-N-acetylgalactosaminidase
chr7_-_144835981 0.49 ENST00000360057.7
ENST00000378099.7
ENST00000639328.1
thiamin pyrophosphokinase 1
chr9_-_27529705 0.46 ENST00000262244.6
MOB kinase activator 3B
chr12_-_55842927 0.45 ENST00000322569.9
ENST00000409200.7
matrix metallopeptidase 19
chr14_+_20781139 0.45 ENST00000304677.3
ribonuclease A family member k6
chr12_-_95996302 0.43 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr1_+_154327737 0.41 ENST00000672630.1
ATPase phospholipid transporting 8B2
chr18_+_63775369 0.40 ENST00000540675.5
serpin family B member 7
chr17_-_76027212 0.40 ENST00000586740.1
envoplakin
chr3_-_114199407 0.39 ENST00000460779.5
dopamine receptor D3
chr12_-_57016517 0.38 ENST00000441881.5
ENST00000458521.7
tachykinin precursor 3
chr6_+_43298326 0.38 ENST00000372574.7
solute carrier family 22 member 7
chr8_-_123737378 0.37 ENST00000419625.6
ENST00000262219.10
annexin A13
chrX_-_152769677 0.36 ENST00000457643.1
ENST00000616035.4
ENST00000412733.1
ENST00000329342.9
MAGE family member A6
chr9_+_27109135 0.35 ENST00000519097.5
ENST00000615002.4
TEK receptor tyrosine kinase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0044278 cell wall disruption in other organism(GO:0044278)
1.6 9.9 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
1.5 4.6 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
1.2 3.6 GO:0036292 DNA rewinding(GO:0036292)
1.1 3.4 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
1.1 7.8 GO:0048241 epinephrine transport(GO:0048241)
1.0 4.2 GO:1990928 response to amino acid starvation(GO:1990928)
1.0 6.2 GO:0016926 protein desumoylation(GO:0016926)
1.0 2.9 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.9 3.4 GO:0009822 alkaloid catabolic process(GO:0009822)
0.8 5.9 GO:0007000 nucleolus organization(GO:0007000)
0.8 5.7 GO:0070560 protein secretion by platelet(GO:0070560)
0.8 2.4 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.7 7.4 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.7 15.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.7 2.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.7 9.9 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.6 24.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.6 1.7 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.6 1.7 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) sarcomerogenesis(GO:0048769)
0.6 6.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.5 1.6 GO:0007525 somatic muscle development(GO:0007525)
0.5 7.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.5 4.5 GO:0003190 atrioventricular valve formation(GO:0003190)
0.4 1.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4 5.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.4 1.9 GO:0046208 polyamine catabolic process(GO:0006598) spermine catabolic process(GO:0046208)
0.4 2.9 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3 3.8 GO:0006108 malate metabolic process(GO:0006108)
0.3 2.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 0.9 GO:0048290 isotype switching to IgA isotypes(GO:0048290)
0.3 1.8 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.3 0.9 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 3.3 GO:0042908 xenobiotic transport(GO:0042908)
0.3 9.2 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.3 10.9 GO:0048665 neuron fate specification(GO:0048665)
0.3 1.7 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.3 1.1 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.3 1.3 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.3 1.6 GO:0008218 bioluminescence(GO:0008218)
0.3 2.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 2.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 2.5 GO:0042737 drug catabolic process(GO:0042737)
0.2 2.1 GO:0007135 meiosis II(GO:0007135)
0.2 3.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 8.9 GO:0035640 exploration behavior(GO:0035640)
0.2 1.5 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 9.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.2 1.4 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 1.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 0.8 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.2 1.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 3.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.2 3.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.2 0.5 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 5.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.3 GO:0043129 surfactant homeostasis(GO:0043129)
0.2 1.5 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.2 2.1 GO:0036158 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.1 0.4 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 1.5 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.1 0.4 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 2.6 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 2.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.5 GO:0032329 serine transport(GO:0032329)
0.1 1.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.6 GO:0001554 luteolysis(GO:0001554)
0.1 4.7 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 9.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 2.3 GO:0044849 estrous cycle(GO:0044849)
0.1 1.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 1.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 1.8 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.8 GO:0051601 exocyst localization(GO:0051601)
0.1 0.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 6.4 GO:0000045 autophagosome assembly(GO:0000045)
0.1 2.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.5 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 5.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 1.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 3.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 2.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 1.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 2.9 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 2.8 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 2.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.0 GO:0050901 activation of phospholipase C activity(GO:0007202) leukocyte tethering or rolling(GO:0050901)
0.0 15.6 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 1.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0006837 serotonin transport(GO:0006837)
0.0 4.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.0 0.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.4 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 2.8 GO:0044070 regulation of anion transport(GO:0044070)
0.0 1.4 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.6 GO:0032570 response to progesterone(GO:0032570)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 1.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 4.1 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 2.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.1 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 2.1 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.7 GO:0006968 cellular defense response(GO:0006968)
0.0 1.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 3.4 GO:0045666 positive regulation of neuron differentiation(GO:0045666)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.6 1.7 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.5 9.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 4.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.2 3.8 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 5.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095)
0.2 1.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 5.4 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.8 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 0.8 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 1.3 GO:0061700 GATOR2 complex(GO:0061700)
0.2 2.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.5 GO:0071439 clathrin complex(GO:0071439)
0.1 14.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.5 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.8 GO:0060091 kinocilium(GO:0060091)
0.1 3.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.7 GO:0032797 SMN complex(GO:0032797)
0.1 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 4.7 GO:0001533 cornified envelope(GO:0001533)
0.1 1.3 GO:0030478 actin cap(GO:0030478)
0.1 14.0 GO:0001650 fibrillar center(GO:0001650)
0.1 5.9 GO:0015030 Cajal body(GO:0015030)
0.1 3.5 GO:0016235 aggresome(GO:0016235)
0.1 8.7 GO:0005901 caveola(GO:0005901)
0.1 14.6 GO:0030018 Z disc(GO:0030018)
0.1 0.9 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 3.6 GO:0043596 nuclear replication fork(GO:0043596)
0.1 3.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 2.6 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.2 GO:0071437 invadopodium(GO:0071437)
0.0 11.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 5.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 6.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 7.4 GO:0030496 midbody(GO:0030496)
0.0 11.7 GO:0045121 membrane raft(GO:0045121)
0.0 2.1 GO:0005844 polysome(GO:0005844)
0.0 11.2 GO:0045177 apical part of cell(GO:0045177)
0.0 2.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.3 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 1.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.4 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 14.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.9 7.8 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.6 6.5 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
1.5 4.6 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
1.0 6.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
1.0 10.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.8 3.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.7 3.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.6 1.9 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 5.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.6 1.7 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.5 24.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.5 9.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.5 1.9 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.4 1.9 GO:0016936 galactoside binding(GO:0016936)
0.4 2.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 3.6 GO:0036310 annealing helicase activity(GO:0036310)
0.3 2.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 3.2 GO:0031433 telethonin binding(GO:0031433)
0.3 1.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 1.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 6.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 5.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 3.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 1.1 GO:0019862 IgA binding(GO:0019862)
0.2 1.6 GO:1990405 protein antigen binding(GO:1990405)
0.2 1.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 1.5 GO:0019863 IgE binding(GO:0019863)
0.2 4.2 GO:0031005 filamin binding(GO:0031005)
0.2 1.8 GO:0051425 PTB domain binding(GO:0051425)
0.2 2.9 GO:0003680 AT DNA binding(GO:0003680)
0.2 2.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 10.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 2.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 3.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 3.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.8 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 0.6 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 3.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 4.9 GO:0000049 tRNA binding(GO:0000049)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 5.7 GO:0030507 spectrin binding(GO:0030507)
0.1 2.1 GO:0008494 translation activator activity(GO:0008494)
0.1 1.3 GO:0045159 myosin II binding(GO:0045159)
0.1 5.3 GO:0030552 cAMP binding(GO:0030552)
0.1 4.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 7.3 GO:0004497 monooxygenase activity(GO:0004497)
0.1 0.5 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 6.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.5 GO:0015925 galactosidase activity(GO:0015925)
0.1 1.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 7.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 12.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 8.9 GO:0002020 protease binding(GO:0002020)
0.0 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 2.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 4.7 GO:0003774 motor activity(GO:0003774)
0.0 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 29.1 GO:0008270 zinc ion binding(GO:0008270)
0.0 2.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 4.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 3.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.7 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 24.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 10.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 12.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 15.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 5.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 4.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 3.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 2.0 PID SHP2 PATHWAY SHP2 signaling
0.1 5.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 1.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.1 PID INSULIN PATHWAY Insulin Pathway
0.0 2.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 8.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.7 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 9.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 6.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 4.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 3.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 6.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 5.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 24.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.2 REACTOME DEFENSINS Genes involved in Defensins
0.1 2.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 8.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 6.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 2.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 2.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 3.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 3.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 5.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 3.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 9.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling