Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for PITX3
Z-value: 9.89
Motif logo
Transcription factors associated with PITX3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
PITX3
|
ENSG00000107859.10 | PITX3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PITX3 | hg38_v1_chr10_-_102241502_102241517 | -0.67 | 7.8e-30 | Click! |
Activity profile of PITX3 motif
Sorted Z-values of PITX3 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of PITX3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.6 | 62.8 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 12.0 | 48.2 | GO:0019860 | uracil metabolic process(GO:0019860) |
| 11.7 | 35.1 | GO:0036292 | DNA rewinding(GO:0036292) |
| 8.4 | 25.1 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
| 7.8 | 54.7 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 7.6 | 68.0 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 6.6 | 19.8 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) |
| 6.4 | 25.6 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 6.2 | 24.7 | GO:0009224 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 6.0 | 84.7 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 5.8 | 17.3 | GO:1903722 | regulation of centriole elongation(GO:1903722) |
| 5.4 | 59.0 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 5.0 | 20.0 | GO:0051311 | meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 4.8 | 14.4 | GO:0097698 | telomere maintenance via base-excision repair(GO:0097698) |
| 4.7 | 14.1 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 4.7 | 28.1 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 4.5 | 13.5 | GO:0005999 | xylulose biosynthetic process(GO:0005999) |
| 4.4 | 13.3 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
| 4.4 | 13.1 | GO:0051821 | negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821) |
| 4.3 | 8.6 | GO:0071733 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 4.3 | 21.3 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 4.3 | 42.6 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 4.1 | 12.4 | GO:0006311 | meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520) |
| 4.1 | 12.2 | GO:0034473 | U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) |
| 4.0 | 15.9 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 3.9 | 11.8 | GO:0045337 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 3.9 | 15.5 | GO:0097102 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 3.9 | 11.6 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 3.7 | 22.3 | GO:1900369 | regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) |
| 3.7 | 11.0 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 3.6 | 21.7 | GO:0051563 | smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) |
| 3.5 | 14.1 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 3.5 | 10.4 | GO:0071314 | cellular response to cocaine(GO:0071314) |
| 3.5 | 24.2 | GO:0008215 | spermine metabolic process(GO:0008215) |
| 3.4 | 20.6 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 3.4 | 10.3 | GO:1904772 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 3.4 | 20.2 | GO:1904688 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 3.3 | 6.7 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) |
| 3.3 | 13.3 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 3.3 | 10.0 | GO:0060739 | mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739) |
| 3.3 | 46.3 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 3.2 | 9.7 | GO:1903015 | regulation of exo-alpha-sialidase activity(GO:1903015) |
| 3.2 | 9.6 | GO:1902594 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 3.2 | 16.0 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 3.2 | 12.7 | GO:0002270 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 3.1 | 18.9 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 3.1 | 6.2 | GO:0071029 | polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046) |
| 3.0 | 12.1 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 3.0 | 18.0 | GO:0097052 | L-kynurenine metabolic process(GO:0097052) |
| 3.0 | 17.8 | GO:0048478 | replication fork protection(GO:0048478) |
| 2.9 | 26.3 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 2.9 | 11.5 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 2.9 | 14.3 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 2.8 | 11.4 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 2.8 | 14.0 | GO:2000542 | negative regulation of gastrulation(GO:2000542) |
| 2.8 | 33.3 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 2.8 | 11.1 | GO:2000077 | UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of type B pancreatic cell development(GO:2000077) |
| 2.8 | 8.3 | GO:0031990 | mRNA export from nucleus in response to heat stress(GO:0031990) recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402) |
| 2.8 | 8.3 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 2.7 | 16.4 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 2.7 | 16.1 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 2.6 | 7.9 | GO:1903925 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 2.6 | 5.3 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 2.6 | 7.8 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
| 2.6 | 10.4 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 2.6 | 15.4 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 2.6 | 43.5 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 2.6 | 186.7 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 2.6 | 10.2 | GO:0061450 | trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163) |
| 2.5 | 20.4 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 2.5 | 10.2 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
| 2.5 | 7.6 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 2.5 | 5.1 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 2.5 | 22.3 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 2.5 | 7.4 | GO:1903006 | flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006) |
| 2.5 | 19.8 | GO:1903027 | regulation of opsonization(GO:1903027) |
| 2.5 | 9.9 | GO:2000354 | regulation of ovarian follicle development(GO:2000354) |
| 2.5 | 12.3 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 2.4 | 4.8 | GO:1903719 | regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) |
| 2.3 | 23.3 | GO:2000576 | positive regulation of microtubule motor activity(GO:2000576) |
| 2.3 | 9.3 | GO:0032595 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
| 2.3 | 32.3 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 2.3 | 6.9 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
| 2.3 | 45.6 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 2.3 | 29.6 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 2.3 | 9.1 | GO:0003285 | septum secundum development(GO:0003285) atrial septum secundum morphogenesis(GO:0003290) |
| 2.3 | 6.8 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 2.3 | 29.3 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 2.2 | 15.4 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 2.2 | 17.6 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 2.2 | 6.6 | GO:1903862 | positive regulation of oxidative phosphorylation(GO:1903862) |
| 2.2 | 30.6 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 2.2 | 8.6 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 2.1 | 17.0 | GO:0002353 | kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) |
| 2.1 | 12.6 | GO:0050668 | cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668) |
| 2.1 | 27.1 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 2.1 | 33.3 | GO:0043248 | proteasome assembly(GO:0043248) |
| 2.1 | 6.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 2.0 | 6.1 | GO:0001300 | chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 2.0 | 14.3 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
| 2.0 | 10.2 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 2.0 | 12.0 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) meiotic sister chromatid cohesion(GO:0051177) |
| 2.0 | 7.9 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 2.0 | 5.9 | GO:0034729 | histone H3-K79 methylation(GO:0034729) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 2.0 | 21.7 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 2.0 | 21.6 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 1.9 | 5.8 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 1.9 | 9.6 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 1.9 | 13.4 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 1.9 | 5.7 | GO:0044752 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 1.9 | 24.5 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 1.9 | 11.3 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
| 1.9 | 9.3 | GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 1.9 | 79.8 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 1.9 | 31.5 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 1.8 | 36.7 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 1.8 | 20.1 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 1.8 | 14.6 | GO:2000373 | phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 1.8 | 30.9 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 1.8 | 9.1 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 1.8 | 9.1 | GO:0015862 | uridine transport(GO:0015862) |
| 1.8 | 10.9 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 1.8 | 5.4 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 1.8 | 5.4 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 1.8 | 3.6 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 1.8 | 7.2 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 1.8 | 12.5 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 1.8 | 10.7 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 1.8 | 15.9 | GO:0007070 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) positive regulation of glucose mediated signaling pathway(GO:1902661) |
| 1.7 | 8.7 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 1.7 | 13.7 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 1.7 | 10.2 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 1.7 | 5.1 | GO:0010040 | response to iron(II) ion(GO:0010040) |
| 1.7 | 6.8 | GO:0060620 | regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910) |
| 1.7 | 10.2 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 1.7 | 5.1 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) |
| 1.7 | 20.0 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 1.7 | 10.0 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 1.7 | 8.3 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 1.6 | 13.2 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 1.6 | 8.2 | GO:0006231 | dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073) |
| 1.6 | 18.0 | GO:2000645 | negative regulation of receptor catabolic process(GO:2000645) |
| 1.6 | 22.8 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 1.6 | 3.3 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 1.6 | 4.8 | GO:0048254 | snoRNA localization(GO:0048254) |
| 1.6 | 22.5 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 1.6 | 39.9 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 1.6 | 4.8 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 1.6 | 30.1 | GO:0003334 | keratinocyte development(GO:0003334) |
| 1.6 | 6.3 | GO:0035803 | egg coat formation(GO:0035803) |
| 1.6 | 4.7 | GO:0097086 | amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798) |
| 1.6 | 7.8 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 1.6 | 153.9 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
| 1.5 | 6.2 | GO:1904504 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
| 1.5 | 24.7 | GO:0051383 | kinetochore organization(GO:0051383) |
| 1.5 | 4.6 | GO:0016487 | sesquiterpenoid metabolic process(GO:0006714) polyprenol catabolic process(GO:0016095) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) |
| 1.5 | 13.8 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 1.5 | 46.0 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 1.5 | 10.4 | GO:0098881 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 1.5 | 7.4 | GO:0001971 | negative regulation of activation of membrane attack complex(GO:0001971) |
| 1.5 | 2.9 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
| 1.4 | 10.1 | GO:0030423 | targeting of mRNA for destruction involved in RNA interference(GO:0030423) |
| 1.4 | 5.8 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 1.4 | 5.7 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 1.4 | 28.3 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 1.4 | 5.7 | GO:0006408 | snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833) |
| 1.4 | 19.7 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
| 1.4 | 22.5 | GO:1903764 | regulation of potassium ion import(GO:1903286) regulation of potassium ion export across plasma membrane(GO:1903764) |
| 1.4 | 4.2 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
| 1.4 | 8.3 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 1.4 | 54.7 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 1.4 | 17.7 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 1.4 | 9.5 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 1.4 | 19.0 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 1.3 | 11.9 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 1.3 | 5.3 | GO:0009956 | radial pattern formation(GO:0009956) |
| 1.3 | 11.6 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 1.3 | 43.8 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 1.3 | 3.8 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 1.3 | 22.8 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 1.3 | 59.4 | GO:0006301 | postreplication repair(GO:0006301) |
| 1.3 | 2.5 | GO:0014806 | smooth muscle hyperplasia(GO:0014806) |
| 1.2 | 8.7 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 1.2 | 7.4 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 1.2 | 29.6 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 1.2 | 6.1 | GO:0019640 | glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159) |
| 1.2 | 29.1 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 1.2 | 4.8 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 1.2 | 10.7 | GO:0043382 | positive regulation of memory T cell differentiation(GO:0043382) |
| 1.2 | 9.5 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 1.2 | 3.5 | GO:0030961 | peptidyl-arginine hydroxylation(GO:0030961) |
| 1.2 | 3.5 | GO:0000478 | endonucleolytic cleavage involved in rRNA processing(GO:0000478) |
| 1.2 | 8.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 1.2 | 23.1 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 1.2 | 30.0 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 1.1 | 9.2 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 1.1 | 3.4 | GO:0072708 | response to sorbitol(GO:0072708) cellular response to sorbitol(GO:0072709) |
| 1.1 | 7.9 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 1.1 | 6.8 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 1.1 | 7.8 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 1.1 | 3.3 | GO:1901253 | regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253) |
| 1.1 | 11.1 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 1.1 | 17.6 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 1.1 | 33.0 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 1.1 | 14.1 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 1.1 | 11.8 | GO:0070900 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 1.1 | 9.6 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 1.1 | 3.2 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 1.1 | 7.5 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 1.1 | 14.8 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 1.0 | 5.2 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 1.0 | 40.4 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 1.0 | 4.1 | GO:0009181 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 1.0 | 12.3 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 1.0 | 2.0 | GO:0019249 | lactate biosynthetic process(GO:0019249) |
| 1.0 | 7.0 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 1.0 | 1.0 | GO:1903625 | negative regulation of DNA catabolic process(GO:1903625) |
| 1.0 | 2.0 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
| 1.0 | 2.9 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 1.0 | 7.7 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 1.0 | 2.9 | GO:1904578 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
| 0.9 | 39.7 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.9 | 4.7 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.9 | 7.5 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.9 | 41.3 | GO:0019430 | removal of superoxide radicals(GO:0019430) |
| 0.9 | 2.8 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 0.9 | 12.0 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.9 | 4.6 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.9 | 12.7 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.9 | 27.9 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.9 | 4.5 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.9 | 7.1 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.9 | 7.1 | GO:0010917 | negative regulation of mitochondrial membrane potential(GO:0010917) |
| 0.9 | 5.3 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.9 | 1.8 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.9 | 10.5 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.9 | 12.0 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.8 | 3.4 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 0.8 | 17.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.8 | 2.5 | GO:0045082 | positive regulation of interleukin-10 biosynthetic process(GO:0045082) |
| 0.8 | 14.8 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.8 | 6.5 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.8 | 5.7 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.8 | 7.3 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.8 | 10.5 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.8 | 15.3 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 0.8 | 25.8 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.8 | 2.4 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 0.8 | 24.1 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.8 | 3.1 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.8 | 7.7 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 0.8 | 9.9 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
| 0.8 | 8.4 | GO:2000795 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.8 | 9.8 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.7 | 16.4 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 0.7 | 5.9 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 0.7 | 2.2 | GO:1903978 | regulation of microglial cell activation(GO:1903978) |
| 0.7 | 4.3 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.7 | 6.3 | GO:0003402 | planar cell polarity pathway involved in axis elongation(GO:0003402) |
| 0.7 | 2.8 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.7 | 6.2 | GO:0042407 | cristae formation(GO:0042407) |
| 0.7 | 3.4 | GO:0051510 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 0.7 | 8.8 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.7 | 17.4 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
| 0.7 | 11.3 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.7 | 2.0 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.7 | 10.6 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.7 | 35.8 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.6 | 2.6 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
| 0.6 | 48.8 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.6 | 3.2 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.6 | 4.5 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.6 | 2.5 | GO:0097021 | lymphocyte migration into lymphoid organs(GO:0097021) |
| 0.6 | 1.9 | GO:0002304 | gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305) |
| 0.6 | 9.4 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 0.6 | 24.3 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.6 | 3.1 | GO:0061622 | glycolytic process through glucose-1-phosphate(GO:0061622) |
| 0.6 | 10.6 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 0.6 | 4.9 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.6 | 6.8 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.6 | 3.0 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.6 | 5.9 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.6 | 3.0 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.6 | 40.1 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.6 | 2.4 | GO:1900127 | positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 0.6 | 1.8 | GO:0036233 | glycine import(GO:0036233) |
| 0.6 | 1.2 | GO:1900126 | regulation of hyaluronan biosynthetic process(GO:1900125) negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.6 | 2.9 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.6 | 2.9 | GO:0046532 | regulation of photoreceptor cell differentiation(GO:0046532) |
| 0.6 | 1.7 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) |
| 0.6 | 1.1 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) |
| 0.6 | 3.9 | GO:0060574 | intestinal epithelial cell maturation(GO:0060574) |
| 0.6 | 17.4 | GO:0015988 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.6 | 3.9 | GO:0060694 | regulation of cholesterol transporter activity(GO:0060694) |
| 0.5 | 1.1 | GO:0036518 | chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643) |
| 0.5 | 2.2 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 0.5 | 1.6 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.5 | 9.2 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.5 | 1.6 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.5 | 2.7 | GO:0006574 | valine catabolic process(GO:0006574) |
| 0.5 | 5.3 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 0.5 | 7.9 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.5 | 6.8 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
| 0.5 | 2.1 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.5 | 4.6 | GO:1903599 | positive regulation of mitophagy(GO:1903599) |
| 0.5 | 3.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.5 | 9.1 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.5 | 2.5 | GO:1905146 | lysosomal protein catabolic process(GO:1905146) |
| 0.5 | 4.0 | GO:0009597 | detection of virus(GO:0009597) |
| 0.5 | 3.0 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.5 | 3.5 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.5 | 9.3 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.5 | 13.1 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
| 0.5 | 7.1 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.5 | 17.1 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.5 | 3.3 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.5 | 20.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.5 | 8.5 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.5 | 1.8 | GO:1903421 | regulation of synaptic vesicle recycling(GO:1903421) |
| 0.4 | 6.7 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.4 | 5.8 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.4 | 8.0 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.4 | 3.9 | GO:0015886 | heme transport(GO:0015886) |
| 0.4 | 8.2 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.4 | 1.7 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.4 | 12.0 | GO:0097340 | inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) |
| 0.4 | 6.8 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.4 | 6.3 | GO:0007567 | parturition(GO:0007567) |
| 0.4 | 0.8 | GO:0018963 | phthalate metabolic process(GO:0018963) |
| 0.4 | 0.8 | GO:0097325 | melanocyte proliferation(GO:0097325) |
| 0.4 | 2.0 | GO:0043126 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.4 | 8.7 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.4 | 4.3 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.4 | 7.5 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.4 | 10.2 | GO:0035456 | response to interferon-beta(GO:0035456) |
| 0.4 | 16.4 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.4 | 3.1 | GO:0072733 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 0.4 | 2.7 | GO:0036476 | neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
| 0.4 | 1.1 | GO:1902739 | interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
| 0.4 | 1.9 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.4 | 2.6 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.4 | 1.1 | GO:1903121 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.4 | 3.3 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
| 0.4 | 1.8 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.4 | 8.0 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.4 | 9.8 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.4 | 1.4 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.4 | 1.8 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.4 | 1.8 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.4 | 1.8 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.4 | 6.1 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.4 | 10.9 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 0.4 | 4.6 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.4 | 2.8 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.3 | 2.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.3 | 2.1 | GO:0019321 | pentose metabolic process(GO:0019321) |
| 0.3 | 1.0 | GO:0008582 | regulation of synaptic growth at neuromuscular junction(GO:0008582) |
| 0.3 | 13.2 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.3 | 8.4 | GO:0075733 | transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) |
| 0.3 | 0.7 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.3 | 3.0 | GO:0008228 | opsonization(GO:0008228) |
| 0.3 | 1.3 | GO:0032079 | positive regulation of deoxyribonuclease activity(GO:0032077) positive regulation of endodeoxyribonuclease activity(GO:0032079) |
| 0.3 | 2.0 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202) |
| 0.3 | 3.6 | GO:0043486 | histone exchange(GO:0043486) |
| 0.3 | 1.0 | GO:0034163 | negative regulation of interferon-alpha production(GO:0032687) regulation of toll-like receptor 9 signaling pathway(GO:0034163) |
| 0.3 | 13.1 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.3 | 3.5 | GO:0007379 | segment specification(GO:0007379) |
| 0.3 | 2.5 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.3 | 5.0 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.3 | 23.4 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.3 | 0.6 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.3 | 13.2 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.3 | 4.6 | GO:0033622 | integrin activation(GO:0033622) |
| 0.3 | 3.4 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.3 | 15.1 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.3 | 1.2 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.3 | 1.5 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 0.3 | 3.5 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.3 | 8.5 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.3 | 27.2 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.3 | 2.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.3 | 0.8 | GO:0038109 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) |
| 0.3 | 2.8 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.3 | 2.8 | GO:0035413 | positive regulation of catenin import into nucleus(GO:0035413) |
| 0.3 | 22.7 | GO:0071427 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.3 | 2.5 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.3 | 11.1 | GO:0043277 | apoptotic cell clearance(GO:0043277) |
| 0.3 | 3.3 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.3 | 12.4 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.3 | 1.1 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.3 | 6.5 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.3 | 11.1 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.3 | 16.5 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.3 | 2.5 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
| 0.2 | 3.2 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.2 | 1.7 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.2 | 2.7 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.2 | 1.9 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.2 | 1.9 | GO:0071374 | cellular response to parathyroid hormone stimulus(GO:0071374) |
| 0.2 | 6.0 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.2 | 2.8 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.2 | 3.0 | GO:0045794 | negative regulation of cell volume(GO:0045794) |
| 0.2 | 8.4 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.2 | 6.1 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.2 | 0.4 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.2 | 3.6 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
| 0.2 | 0.7 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.2 | 3.5 | GO:0042226 | interleukin-6 biosynthetic process(GO:0042226) |
| 0.2 | 6.8 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.2 | 25.4 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.2 | 28.0 | GO:0030705 | cytoskeleton-dependent intracellular transport(GO:0030705) |
| 0.2 | 1.7 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.2 | 9.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.2 | 3.9 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.2 | 1.0 | GO:0061087 | regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.2 | 8.7 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.2 | 6.6 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.2 | 1.4 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.2 | 1.3 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.2 | 3.3 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.2 | 0.5 | GO:0061743 | motor learning(GO:0061743) |
| 0.2 | 1.2 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.2 | 1.2 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.2 | 4.4 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 0.2 | 5.2 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.2 | 5.2 | GO:0051972 | regulation of telomerase activity(GO:0051972) |
| 0.2 | 9.2 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.2 | 0.3 | GO:2001267 | regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001267) |
| 0.2 | 0.5 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.2 | 12.1 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.2 | 0.5 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.2 | 9.1 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.2 | 0.6 | GO:0034629 | cellular protein complex localization(GO:0034629) |
| 0.2 | 3.7 | GO:0030890 | positive regulation of B cell proliferation(GO:0030890) |
| 0.2 | 1.1 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.2 | 0.5 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.2 | 1.7 | GO:2000650 | negative regulation of sodium ion transport(GO:0010766) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650) |
| 0.2 | 1.4 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 0.8 | GO:1904417 | regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417) |
| 0.2 | 0.9 | GO:0060356 | leucine import(GO:0060356) |
| 0.1 | 5.8 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
| 0.1 | 2.8 | GO:0071354 | cellular response to interleukin-6(GO:0071354) |
| 0.1 | 1.2 | GO:2000641 | regulation of early endosome to late endosome transport(GO:2000641) |
| 0.1 | 16.2 | GO:0060348 | bone development(GO:0060348) |
| 0.1 | 0.4 | GO:0045656 | negative regulation of monocyte differentiation(GO:0045656) |
| 0.1 | 2.4 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.1 | 1.3 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 3.9 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 1.4 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.1 | 1.2 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 0.1 | 1.5 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.1 | 2.5 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186) |
| 0.1 | 0.4 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
| 0.1 | 8.5 | GO:0060337 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.1 | 4.4 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.1 | 10.5 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.1 | 0.4 | GO:0034442 | regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) |
| 0.1 | 2.6 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 2.8 | GO:0006414 | translational elongation(GO:0006414) |
| 0.1 | 0.8 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.1 | 4.0 | GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) |
| 0.1 | 1.4 | GO:0045577 | regulation of B cell differentiation(GO:0045577) |
| 0.1 | 0.6 | GO:0071569 | protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 2.6 | GO:0006754 | ATP biosynthetic process(GO:0006754) |
| 0.1 | 2.1 | GO:0042438 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
| 0.1 | 2.6 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 0.4 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.1 | 2.6 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.1 | 0.4 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 0.1 | 0.3 | GO:0050428 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.1 | 6.2 | GO:0050772 | positive regulation of axonogenesis(GO:0050772) |
| 0.1 | 1.1 | GO:0060117 | auditory receptor cell development(GO:0060117) |
| 0.1 | 1.9 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 1.3 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.1 | 0.4 | GO:0098704 | fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.1 | 2.0 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
| 0.1 | 0.3 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.1 | 0.5 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 0.1 | 0.3 | GO:2000563 | positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
| 0.1 | 0.1 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.1 | 0.8 | GO:0006337 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) |
| 0.1 | 5.6 | GO:0006364 | rRNA processing(GO:0006364) |
| 0.0 | 0.7 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.0 | 2.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 7.3 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.0 | 0.3 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.0 | 0.6 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 2.2 | GO:0002220 | innate immune response activating cell surface receptor signaling pathway(GO:0002220) |
| 0.0 | 0.1 | GO:0061043 | regulation of vascular wound healing(GO:0061043) |
| 0.0 | 0.1 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.0 | 0.6 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.0 | 1.6 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.0 | 2.1 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.0 | 0.2 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.0 | 0.1 | GO:0015871 | choline transport(GO:0015871) |
| 0.0 | 0.3 | GO:0086069 | bundle of His cell to Purkinje myocyte communication(GO:0086069) |
| 0.0 | 0.2 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.3 | 68.0 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 10.8 | 53.8 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 9.2 | 27.6 | GO:0036194 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 9.1 | 36.5 | GO:0071986 | Ragulator complex(GO:0071986) |
| 7.4 | 51.6 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 7.1 | 42.4 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 6.8 | 6.8 | GO:0034665 | integrin alpha1-beta1 complex(GO:0034665) |
| 6.6 | 19.7 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
| 6.5 | 84.7 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 5.7 | 17.1 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 5.6 | 44.9 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 5.6 | 22.3 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 5.4 | 38.0 | GO:0032021 | NELF complex(GO:0032021) |
| 5.4 | 75.7 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 5.0 | 20.0 | GO:0005715 | late recombination nodule(GO:0005715) |
| 4.7 | 14.2 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 4.7 | 18.9 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 4.7 | 14.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 4.5 | 27.0 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 4.5 | 22.5 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 4.5 | 13.4 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 4.4 | 13.2 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 4.4 | 43.8 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 4.2 | 8.4 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 3.9 | 63.0 | GO:0005642 | annulate lamellae(GO:0005642) |
| 3.8 | 30.6 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 3.8 | 15.3 | GO:0000811 | GINS complex(GO:0000811) |
| 3.6 | 10.7 | GO:0034455 | t-UTP complex(GO:0034455) |
| 3.5 | 10.6 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 3.4 | 10.2 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 3.2 | 9.6 | GO:0036284 | tubulobulbar complex(GO:0036284) |
| 2.9 | 11.5 | GO:1990423 | RZZ complex(GO:1990423) |
| 2.8 | 42.6 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 2.8 | 19.7 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 2.8 | 33.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 2.8 | 11.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 2.8 | 8.3 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 2.7 | 46.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 2.7 | 13.5 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 2.7 | 29.5 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 2.6 | 40.9 | GO:0097470 | ribbon synapse(GO:0097470) |
| 2.5 | 22.7 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 2.5 | 32.2 | GO:0005688 | U6 snRNP(GO:0005688) |
| 2.5 | 12.4 | GO:0032301 | MutSalpha complex(GO:0032301) MutSbeta complex(GO:0032302) |
| 2.4 | 9.7 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 2.4 | 9.7 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 2.4 | 26.4 | GO:0005638 | lamin filament(GO:0005638) |
| 2.4 | 35.9 | GO:0045120 | pronucleus(GO:0045120) |
| 2.4 | 19.1 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 2.4 | 23.6 | GO:0070552 | BRISC complex(GO:0070552) |
| 2.4 | 23.6 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 2.4 | 11.8 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 2.3 | 23.2 | GO:0044754 | autolysosome(GO:0044754) |
| 2.2 | 23.9 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 2.1 | 16.8 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 2.0 | 10.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 2.0 | 16.1 | GO:0000796 | condensin complex(GO:0000796) |
| 2.0 | 12.0 | GO:0033063 | DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 2.0 | 12.0 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 1.9 | 7.7 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 1.9 | 11.5 | GO:0005955 | calcineurin complex(GO:0005955) |
| 1.9 | 5.7 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 1.9 | 22.5 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 1.9 | 16.8 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 1.9 | 7.4 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 1.8 | 17.5 | GO:0097443 | sorting endosome(GO:0097443) |
| 1.7 | 25.9 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 1.7 | 6.8 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 1.6 | 4.9 | GO:0005606 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 1.6 | 14.7 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 1.6 | 30.9 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 1.6 | 31.7 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 1.6 | 18.9 | GO:0097427 | microtubule bundle(GO:0097427) |
| 1.6 | 11.0 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 1.5 | 6.2 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 1.5 | 4.6 | GO:0097409 | glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038) |
| 1.5 | 27.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 1.5 | 18.2 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 1.5 | 10.6 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 1.5 | 16.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 1.5 | 86.2 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 1.5 | 11.7 | GO:0005827 | polar microtubule(GO:0005827) |
| 1.4 | 4.3 | GO:0005592 | collagen type XI trimer(GO:0005592) |
| 1.4 | 5.7 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 1.4 | 14.0 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 1.4 | 21.8 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 1.4 | 10.9 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 1.3 | 4.0 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 1.3 | 17.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 1.3 | 6.6 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 1.3 | 6.6 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 1.3 | 80.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 1.3 | 9.1 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 1.2 | 33.7 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 1.2 | 6.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 1.2 | 22.2 | GO:0005839 | proteasome core complex(GO:0005839) |
| 1.2 | 9.8 | GO:0097255 | R2TP complex(GO:0097255) |
| 1.2 | 3.6 | GO:0030689 | Noc complex(GO:0030689) |
| 1.2 | 5.9 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 1.2 | 15.2 | GO:0030478 | actin cap(GO:0030478) |
| 1.2 | 12.7 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 1.1 | 12.6 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 1.1 | 5.4 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 1.1 | 9.7 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 1.1 | 22.5 | GO:0043219 | lateral loop(GO:0043219) |
| 1.1 | 7.5 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 1.0 | 29.3 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 1.0 | 31.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 1.0 | 6.2 | GO:0061617 | MICOS complex(GO:0061617) |
| 1.0 | 22.4 | GO:0030686 | 90S preribosome(GO:0030686) |
| 1.0 | 11.1 | GO:0030870 | Mre11 complex(GO:0030870) |
| 1.0 | 99.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 1.0 | 7.8 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 1.0 | 11.6 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 1.0 | 6.7 | GO:0000243 | commitment complex(GO:0000243) |
| 0.9 | 44.2 | GO:0002102 | podosome(GO:0002102) |
| 0.9 | 7.5 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.9 | 27.6 | GO:0016469 | proton-transporting two-sector ATPase complex(GO:0016469) |
| 0.9 | 9.1 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.9 | 22.6 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.9 | 5.3 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 0.9 | 10.6 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.9 | 14.9 | GO:0008091 | spectrin(GO:0008091) |
| 0.9 | 8.7 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.9 | 12.0 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.8 | 4.2 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.8 | 27.8 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.8 | 7.2 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.8 | 8.8 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.8 | 3.9 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.8 | 7.6 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.7 | 22.7 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.7 | 16.0 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.7 | 1.4 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 0.7 | 81.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.7 | 11.9 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.7 | 12.5 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.6 | 2.5 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.6 | 8.0 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.6 | 1.2 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.6 | 13.0 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.6 | 25.8 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.6 | 9.6 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.6 | 7.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.5 | 4.3 | GO:1905202 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 0.5 | 12.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.5 | 8.0 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.5 | 16.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.5 | 3.1 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.5 | 3.1 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.5 | 3.6 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.5 | 6.5 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.5 | 2.5 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.5 | 7.4 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.5 | 4.4 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.5 | 2.4 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.5 | 32.2 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.5 | 5.8 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.5 | 4.3 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.5 | 63.3 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.5 | 2.3 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.5 | 2.8 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.4 | 40.7 | GO:0031970 | organelle envelope lumen(GO:0031970) |
| 0.4 | 1.3 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 0.4 | 12.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.4 | 11.1 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.4 | 1.3 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.4 | 5.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.4 | 50.6 | GO:0005840 | ribosome(GO:0005840) |
| 0.4 | 13.7 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.4 | 12.0 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.4 | 7.2 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.4 | 1.7 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.4 | 11.2 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.4 | 8.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.4 | 47.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.4 | 12.0 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.4 | 3.0 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.4 | 4.8 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.4 | 1.1 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.4 | 20.4 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.4 | 0.7 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.4 | 3.9 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.4 | 24.6 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.3 | 4.6 | GO:0000145 | exocyst(GO:0000145) |
| 0.3 | 0.7 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.3 | 14.7 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.3 | 6.8 | GO:0005861 | troponin complex(GO:0005861) |
| 0.3 | 4.1 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.3 | 5.9 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.3 | 42.4 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.3 | 18.2 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.3 | 6.1 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.3 | 27.0 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.3 | 4.9 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.3 | 18.5 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.3 | 1.7 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.3 | 69.2 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.3 | 40.0 | GO:0005903 | brush border(GO:0005903) |
| 0.3 | 8.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.2 | 2.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.2 | 9.1 | GO:0016235 | aggresome(GO:0016235) |
| 0.2 | 23.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.2 | 1.2 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.2 | 5.1 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.2 | 2.1 | GO:0032059 | bleb(GO:0032059) |
| 0.2 | 2.9 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 2.9 | GO:0042555 | MCM complex(GO:0042555) |
| 0.2 | 2.4 | GO:0071203 | WASH complex(GO:0071203) |
| 0.2 | 7.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.2 | 31.9 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.2 | 1.5 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.2 | 0.5 | GO:0030684 | preribosome(GO:0030684) |
| 0.2 | 5.8 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.2 | 5.6 | GO:0044215 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.2 | 3.0 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.2 | 0.5 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.2 | 3.4 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.2 | 4.6 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.2 | 20.7 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.2 | 10.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.2 | 6.0 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.2 | 5.0 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.2 | 3.4 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.1 | 4.1 | GO:0005844 | polysome(GO:0005844) |
| 0.1 | 2.2 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.1 | 0.5 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.1 | 7.5 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 2.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 1.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 1.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 50.8 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.1 | 4.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 36.6 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 0.6 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 26.5 | GO:0030529 | intracellular ribonucleoprotein complex(GO:0030529) |
| 0.1 | 2.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 37.8 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 6.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 12.3 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 8.7 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 7.0 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 13.2 | GO:0005741 | mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968) |
| 0.1 | 8.4 | GO:0005819 | spindle(GO:0005819) |
| 0.1 | 1.0 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 4.8 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 19.4 | GO:0005874 | microtubule(GO:0005874) |
| 0.1 | 0.2 | GO:0032300 | mismatch repair complex(GO:0032300) MutLalpha complex(GO:0032389) |
| 0.0 | 1.4 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 2.4 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 0.1 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.4 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 13.0 | GO:0005730 | nucleolus(GO:0005730) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.5 | 42.3 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 6.8 | 20.3 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) |
| 6.0 | 18.0 | GO:0047315 | kynurenine-glyoxylate transaminase activity(GO:0047315) |
| 5.9 | 35.6 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 5.9 | 17.7 | GO:0000035 | acyl binding(GO:0000035) |
| 4.9 | 43.8 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 4.7 | 14.1 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 4.7 | 32.6 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 4.5 | 18.1 | GO:0004487 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 4.5 | 17.9 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 4.4 | 30.5 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 4.3 | 34.6 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 4.2 | 12.7 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 4.1 | 52.8 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 4.0 | 12.0 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 3.9 | 59.0 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 3.8 | 11.3 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 3.7 | 22.3 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 3.7 | 37.0 | GO:0042731 | PH domain binding(GO:0042731) |
| 3.7 | 11.0 | GO:0031208 | POZ domain binding(GO:0031208) |
| 3.7 | 14.6 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 3.6 | 25.5 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 3.6 | 14.4 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 3.5 | 17.6 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 3.4 | 10.2 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 3.4 | 27.2 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 3.3 | 33.2 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 3.3 | 13.2 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 3.3 | 62.0 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 3.2 | 88.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 3.1 | 15.4 | GO:0004082 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 3.0 | 35.7 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 2.8 | 14.2 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 2.8 | 19.8 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 2.8 | 8.3 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 2.8 | 8.3 | GO:0004750 | ribulose-phosphate 3-epimerase activity(GO:0004750) |
| 2.7 | 13.5 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
| 2.7 | 10.7 | GO:0030622 | U4atac snRNA binding(GO:0030622) |
| 2.6 | 47.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 2.6 | 20.8 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 2.6 | 90.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 2.6 | 15.5 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 2.6 | 7.7 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 2.4 | 12.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 2.4 | 21.3 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 2.4 | 11.8 | GO:0004161 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 2.3 | 9.1 | GO:0043515 | kinetochore binding(GO:0043515) |
| 2.2 | 17.6 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 2.2 | 60.9 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 2.1 | 55.8 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 2.1 | 8.5 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 2.1 | 8.3 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 2.1 | 6.2 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 2.0 | 10.2 | GO:0004905 | type I interferon receptor activity(GO:0004905) |
| 2.0 | 8.1 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 2.0 | 6.1 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 2.0 | 6.0 | GO:0043035 | chromatin insulator sequence binding(GO:0043035) |
| 2.0 | 20.0 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 2.0 | 8.0 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 2.0 | 7.9 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 2.0 | 9.8 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 2.0 | 17.6 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 1.9 | 9.7 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 1.9 | 7.8 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 1.9 | 9.5 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 1.9 | 7.6 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 1.9 | 7.6 | GO:0051748 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 1.9 | 5.7 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 1.9 | 18.9 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 1.9 | 13.1 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 1.9 | 9.3 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 1.9 | 5.6 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 1.9 | 20.4 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 1.8 | 11.0 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 1.8 | 12.7 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 1.8 | 12.7 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 1.8 | 10.5 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 1.7 | 12.0 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 1.7 | 6.8 | GO:0032357 | oxidized purine DNA binding(GO:0032357) |
| 1.7 | 30.5 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 1.7 | 37.0 | GO:0008494 | translation activator activity(GO:0008494) |
| 1.7 | 16.7 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 1.7 | 5.0 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 1.7 | 21.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 1.6 | 11.4 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 1.6 | 13.0 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 1.6 | 4.8 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 1.6 | 70.2 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 1.6 | 63.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 1.6 | 11.1 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 1.6 | 7.8 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 1.6 | 74.6 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 1.5 | 4.6 | GO:0045550 | geranylgeranyl reductase activity(GO:0045550) |
| 1.5 | 31.8 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 1.5 | 12.0 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 1.5 | 7.5 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 1.5 | 26.3 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 1.5 | 8.8 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 1.4 | 5.7 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 1.4 | 7.1 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 1.4 | 31.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 1.4 | 10.0 | GO:0045545 | syndecan binding(GO:0045545) |
| 1.4 | 25.4 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 1.4 | 12.6 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 1.4 | 4.1 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 1.4 | 4.1 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 1.4 | 12.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 1.4 | 6.8 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 1.4 | 5.4 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 1.4 | 29.8 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 1.3 | 10.7 | GO:0051425 | PTB domain binding(GO:0051425) |
| 1.3 | 6.7 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 1.3 | 18.4 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 1.3 | 3.9 | GO:0080101 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 1.3 | 6.5 | GO:0097617 | annealing helicase activity(GO:0036310) annealing activity(GO:0097617) |
| 1.3 | 19.5 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 1.3 | 9.1 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 1.3 | 6.5 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 1.2 | 27.8 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 1.2 | 23.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 1.2 | 31.0 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 1.2 | 34.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 1.2 | 3.5 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 1.1 | 6.7 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 1.1 | 4.3 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 1.1 | 6.4 | GO:0000182 | rDNA binding(GO:0000182) |
| 1.1 | 26.7 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 1.1 | 27.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 1.1 | 23.2 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 1.1 | 27.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 1.1 | 7.4 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 1.0 | 5.2 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 1.0 | 9.2 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 1.0 | 34.2 | GO:0000049 | tRNA binding(GO:0000049) |
| 1.0 | 12.0 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 1.0 | 9.8 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 1.0 | 34.3 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 1.0 | 42.1 | GO:0061650 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.9 | 15.9 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.9 | 5.6 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.9 | 6.5 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.9 | 3.7 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.9 | 14.6 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.9 | 105.2 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.9 | 3.5 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.9 | 7.0 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.9 | 6.1 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.9 | 21.0 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.9 | 2.6 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
| 0.9 | 12.9 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 0.9 | 6.8 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.8 | 8.5 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.8 | 4.2 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.8 | 2.5 | GO:0016822 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.8 | 8.4 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 0.8 | 21.2 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.8 | 3.3 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.8 | 11.3 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.8 | 8.0 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.8 | 3.2 | GO:0004335 | galactokinase activity(GO:0004335) |
| 0.8 | 6.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.8 | 7.0 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.8 | 21.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.8 | 2.3 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.8 | 10.6 | GO:0050542 | icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
| 0.7 | 1.5 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.7 | 12.2 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 0.7 | 2.9 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.7 | 13.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.7 | 13.4 | GO:1901611 | phosphatidylglycerol binding(GO:1901611) |
| 0.7 | 8.4 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.7 | 4.2 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.7 | 2.1 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
| 0.7 | 6.2 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.7 | 17.7 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.7 | 27.6 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.7 | 14.7 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.7 | 26.8 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.7 | 2.0 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.6 | 18.2 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.6 | 50.0 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.6 | 10.1 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.6 | 5.7 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.6 | 13.7 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 0.6 | 3.7 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.6 | 18.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.6 | 16.3 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.6 | 2.4 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.6 | 15.7 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.6 | 3.0 | GO:0004549 | tRNA-specific ribonuclease activity(GO:0004549) |
| 0.6 | 4.8 | GO:0003909 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.6 | 4.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.6 | 23.8 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.6 | 14.2 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.6 | 15.9 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.6 | 42.3 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.6 | 8.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.6 | 5.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.6 | 2.3 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.6 | 4.0 | GO:0034594 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
| 0.6 | 2.2 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.6 | 12.3 | GO:0044769 | hydrogen-exporting ATPase activity(GO:0036442) ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.6 | 232.9 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.6 | 16.6 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.5 | 90.7 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.5 | 16.7 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.5 | 27.5 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.5 | 3.1 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.5 | 11.3 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.5 | 2.5 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.5 | 4.5 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.5 | 0.5 | GO:0005350 | pyrimidine nucleobase transmembrane transporter activity(GO:0005350) |
| 0.5 | 3.9 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.5 | 20.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.5 | 6.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.5 | 9.0 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.5 | 7.4 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.5 | 3.2 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.4 | 10.7 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.4 | 2.2 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.4 | 2.1 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.4 | 33.9 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.4 | 26.6 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.4 | 10.3 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.4 | 5.9 | GO:0016208 | AMP binding(GO:0016208) |
| 0.4 | 7.5 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.4 | 6.4 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.4 | 27.7 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.4 | 1.8 | GO:0016723 | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
| 0.4 | 21.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.4 | 2.2 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.4 | 12.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.4 | 11.1 | GO:0033558 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
| 0.4 | 13.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.3 | 6.2 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.3 | 1.0 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.3 | 19.4 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
| 0.3 | 4.0 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.3 | 5.7 | GO:0016859 | cis-trans isomerase activity(GO:0016859) |
| 0.3 | 10.2 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.3 | 10.1 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.3 | 14.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.3 | 1.2 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.3 | 54.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.3 | 1.2 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.3 | 9.7 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.3 | 9.6 | GO:0004386 | helicase activity(GO:0004386) |
| 0.3 | 2.7 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.3 | 8.6 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.3 | 7.8 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.3 | 4.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.3 | 1.1 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.3 | 25.7 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.3 | 6.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.3 | 0.8 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.3 | 2.9 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.3 | 3.1 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 0.3 | 5.6 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.3 | 2.8 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.3 | 2.5 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.3 | 1.8 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.3 | 3.3 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.2 | 1.7 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.2 | 1.0 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.2 | 1.2 | GO:0034481 | chondroitin sulfotransferase activity(GO:0034481) |
| 0.2 | 11.2 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.2 | 1.2 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.2 | 2.5 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.2 | 1.1 | GO:0071253 | connexin binding(GO:0071253) |
| 0.2 | 0.7 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.2 | 5.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.2 | 0.4 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.2 | 2.9 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.2 | 2.4 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.2 | 4.8 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.2 | 3.6 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.2 | 3.8 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.2 | 0.6 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 0.2 | 2.8 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.2 | 11.8 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.2 | 214.4 | GO:0003723 | RNA binding(GO:0003723) |
| 0.2 | 1.9 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.2 | 1.7 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.2 | 2.7 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.2 | 1.2 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.2 | 4.3 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.2 | 18.4 | GO:0042393 | histone binding(GO:0042393) |
| 0.2 | 1.9 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.2 | 1.1 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.2 | 2.0 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.2 | 0.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 3.0 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 42.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 5.1 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.1 | 3.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.7 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 1.2 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 1.5 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 0.4 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.1 | 2.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 5.3 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.1 | 1.7 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 0.7 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 1.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 4.4 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.9 | GO:0031386 | protein tag(GO:0031386) |
| 0.1 | 0.6 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.1 | 4.5 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.1 | 0.4 | GO:0070061 | fructose binding(GO:0070061) |
| 0.1 | 0.3 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.1 | 1.0 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 2.8 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.1 | 0.6 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 0.1 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.1 | 0.2 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.1 | 1.1 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.1 | 0.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.1 | 0.5 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.0 | 4.1 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.4 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 2.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.3 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 1.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.1 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.0 | 0.2 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.0 | 2.7 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.1 | GO:0015199 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
| 0.0 | 3.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.2 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.0 | 0.2 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.0 | 0.1 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.0 | 3.4 | GO:0061659 | ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 0.8 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.4 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.1 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.0 | 0.3 | GO:0048185 | activin binding(GO:0048185) |
| 0.0 | 0.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.6 | 13.2 | ST ADRENERGIC | Adrenergic Pathway |
| 2.6 | 59.0 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 1.5 | 106.1 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 1.2 | 15.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 1.2 | 70.7 | PID AURORA B PATHWAY | Aurora B signaling |
| 1.1 | 47.5 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 1.0 | 27.3 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.9 | 33.3 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.8 | 19.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.8 | 28.6 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.8 | 8.6 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.8 | 25.6 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.8 | 12.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.8 | 34.9 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.8 | 5.3 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.7 | 7.7 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.7 | 58.0 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.7 | 80.1 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.7 | 32.6 | PID MYC PATHWAY | C-MYC pathway |
| 0.6 | 6.2 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.6 | 21.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.5 | 45.9 | PID E2F PATHWAY | E2F transcription factor network |
| 0.5 | 30.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.5 | 18.9 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.5 | 30.1 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.5 | 12.3 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.5 | 22.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.5 | 9.2 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.5 | 10.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.4 | 42.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.4 | 13.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.4 | 44.1 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.4 | 33.6 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.4 | 12.1 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.4 | 8.8 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.3 | 7.9 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.3 | 13.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.3 | 14.3 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.3 | 3.0 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.3 | 3.0 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.3 | 10.3 | PID ATR PATHWAY | ATR signaling pathway |
| 0.3 | 42.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.3 | 2.5 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.3 | 15.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.3 | 3.1 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.3 | 14.6 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.3 | 6.1 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.3 | 9.0 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.3 | 6.4 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.2 | 18.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.2 | 14.6 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.2 | 3.0 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.2 | 5.7 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.2 | 8.6 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.2 | 2.1 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.2 | 6.9 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.2 | 8.0 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.2 | 4.1 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.2 | 5.4 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.2 | 9.8 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 1.6 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.1 | 4.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 9.6 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 1.2 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.1 | 2.2 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 1.1 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 4.2 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 3.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 1.8 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 3.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 3.0 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 1.7 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 5.0 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 3.1 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 0.3 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 2.0 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 1.5 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.4 | 142.0 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 4.1 | 36.8 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 3.4 | 64.0 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 2.9 | 117.6 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 2.9 | 82.0 | REACTOME KINESINS | Genes involved in Kinesins |
| 2.6 | 7.9 | REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
| 2.6 | 163.7 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 2.5 | 10.2 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 2.5 | 211.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 2.4 | 26.3 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 2.1 | 64.2 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 1.9 | 30.4 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 1.8 | 26.5 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 1.7 | 32.2 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 1.7 | 66.0 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 1.6 | 14.4 | REACTOME ORC1 REMOVAL FROM CHROMATIN | Genes involved in Orc1 removal from chromatin |
| 1.5 | 86.4 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 1.4 | 35.8 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 1.4 | 14.0 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 1.4 | 37.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 1.4 | 13.7 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 1.3 | 24.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 1.3 | 16.8 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 1.3 | 20.2 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 1.3 | 72.7 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 1.2 | 22.3 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 1.2 | 14.8 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 1.2 | 25.2 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 1.1 | 41.2 | REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| 1.1 | 25.8 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 1.0 | 12.2 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 1.0 | 33.3 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 1.0 | 30.0 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 1.0 | 18.9 | REACTOME DEADENYLATION DEPENDENT MRNA DECAY | Genes involved in Deadenylation-dependent mRNA decay |
| 1.0 | 44.5 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 1.0 | 27.6 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 1.0 | 22.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 1.0 | 22.1 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 1.0 | 24.7 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.9 | 218.3 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.9 | 25.1 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.9 | 8.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.9 | 24.2 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.8 | 96.3 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.8 | 12.5 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.7 | 29.7 | REACTOME RNA POL III TRANSCRIPTION | Genes involved in RNA Polymerase III Transcription |
| 0.7 | 16.6 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.7 | 16.5 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.7 | 26.1 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.6 | 47.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.6 | 14.8 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.6 | 19.9 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.6 | 20.5 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.6 | 14.0 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.6 | 13.9 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.5 | 27.4 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.5 | 12.7 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.5 | 11.2 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.5 | 20.5 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.5 | 13.8 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.4 | 6.9 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.4 | 13.3 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.4 | 11.9 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.4 | 9.4 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.4 | 9.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.4 | 17.4 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.4 | 9.8 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.4 | 11.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.4 | 13.0 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.4 | 9.4 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.3 | 18.6 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.3 | 3.4 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.3 | 5.7 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.3 | 12.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.3 | 1.2 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.3 | 20.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.3 | 3.8 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.3 | 21.3 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.3 | 0.8 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.3 | 3.0 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.3 | 1.3 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.3 | 6.8 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.2 | 7.7 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.2 | 8.3 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 7.0 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.2 | 7.4 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.2 | 10.7 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.2 | 12.3 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.2 | 6.3 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.2 | 10.0 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.2 | 2.5 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.2 | 3.6 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.2 | 20.0 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.2 | 4.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.2 | 28.8 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 5.2 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.2 | 3.5 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.2 | 2.6 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.2 | 0.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.2 | 11.7 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.2 | 5.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.2 | 2.8 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 4.0 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 2.5 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 0.4 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 3.5 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.1 | 4.1 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 1.2 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 6.3 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 2.1 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.1 | 1.1 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 0.7 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 0.7 | REACTOME DAG AND IP3 SIGNALING | Genes involved in DAG and IP3 signaling |
| 0.1 | 3.1 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.1 | 6.7 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.1 | 1.1 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.1 | 3.3 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 3.3 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 2.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 2.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.2 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 0.4 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.6 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 2.2 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.0 | 0.4 | REACTOME GAP JUNCTION TRAFFICKING | Genes involved in Gap junction trafficking |
| 0.0 | 0.8 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.0 | 0.2 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |