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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for POU1F1

Z-value: 1.15

Motif logo

Transcription factors associated with POU1F1

Gene Symbol Gene ID Gene Info
ENSG00000064835.12 POU1F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU1F1hg38_v1_chr3_-_87276462_872764940.221.2e-03Click!

Activity profile of POU1F1 motif

Sorted Z-values of POU1F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU1F1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_30387064 7.06 ENST00000523115.5
ENST00000519647.5
RNA binding protein, mRNA processing factor
chr15_-_60398733 6.67 ENST00000559818.6
annexin A2
chr3_+_138621225 6.62 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr4_+_25160631 6.56 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr5_-_126595237 6.02 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr7_-_45921264 5.91 ENST00000613132.5
ENST00000381083.9
ENST00000381086.9
insulin like growth factor binding protein 3
chr18_+_23689439 5.71 ENST00000313654.14
laminin subunit alpha 3
chr15_-_60397964 5.43 ENST00000558998.5
ENST00000560165.5
ENST00000557986.5
ENST00000559467.5
ENST00000677968.1
ENST00000678450.1
ENST00000332680.8
ENST00000396024.7
ENST00000557906.6
ENST00000558558.6
ENST00000559113.6
ENST00000559780.6
ENST00000559956.6
ENST00000560468.6
ENST00000678870.1
ENST00000678061.1
ENST00000451270.7
ENST00000421017.6
ENST00000560466.5
ENST00000558132.5
ENST00000559370.5
ENST00000559725.5
ENST00000558985.6
ENST00000679109.1
annexin A2
chr19_+_9087061 5.42 ENST00000641627.1
olfactory receptor family 1 subfamily M member 1
chr1_+_232950580 5.39 ENST00000366628.10
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr19_-_9219589 5.29 ENST00000641244.1
ENST00000641669.1
olfactory receptor family 7 subfamily D member 4
chr18_+_23689609 5.25 ENST00000399516.7
laminin subunit alpha 3
chr2_-_189179754 5.07 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr1_-_45522870 4.94 ENST00000424390.2
peroxiredoxin 1
chr8_+_30442602 4.93 ENST00000520191.5
RNA binding protein, mRNA processing factor
chr6_+_29301701 4.88 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr7_+_107583919 4.87 ENST00000491150.5
B cell receptor associated protein 29
chrX_-_103688090 4.70 ENST00000433176.6
mortality factor 4 like 2
chrX_-_103688033 4.55 ENST00000434230.5
ENST00000418819.5
ENST00000360458.5
mortality factor 4 like 2
chr15_+_41286011 4.51 ENST00000661438.1
novel protein
chr3_+_138621207 4.45 ENST00000464668.5
Fas apoptotic inhibitory molecule
chr2_-_86105839 4.33 ENST00000263857.11
RNA polymerase I subunit A
chr10_-_28282086 4.12 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr10_+_60778331 4.03 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
cyclin dependent kinase 1
chr13_+_30422487 3.89 ENST00000638137.1
ENST00000635918.2
ubiquitin conjugating enzyme E2 L5
chr15_+_65550819 3.87 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr7_+_130486324 3.85 ENST00000427521.6
ENST00000378576.9
mesoderm specific transcript
chr7_+_130486171 3.84 ENST00000341441.9
ENST00000416162.7
mesoderm specific transcript
chr19_+_9185594 3.46 ENST00000344248.4
olfactory receptor family 7 subfamily D member 2
chr10_+_17228215 3.35 ENST00000544301.7
vimentin
chr3_+_52211442 3.30 ENST00000459884.1
5'-aminolevulinate synthase 1
chr14_+_61697622 3.30 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chr15_-_56465130 3.25 ENST00000260453.4
meiosis specific nuclear structural 1
chr5_+_154941063 3.22 ENST00000523037.6
ENST00000265229.12
ENST00000439747.7
ENST00000522038.5
mitochondrial ribosomal protein L22
chr7_+_130293134 3.20 ENST00000445470.6
ENST00000492072.5
ENST00000222482.10
ENST00000473956.5
ENST00000493259.5
ENST00000486598.1
carboxypeptidase A4
chr9_+_69145463 3.11 ENST00000636438.1
tight junction protein 2
chr15_-_66356672 3.09 ENST00000261881.9
TIMELESS interacting protein
chr1_-_93681829 3.06 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr11_-_107858777 3.03 ENST00000525815.6
solute carrier family 35 member F2
chr1_-_53945584 2.99 ENST00000371377.3
heat shock protein family B (small) member 11
chr1_-_53945567 2.98 ENST00000371378.6
heat shock protein family B (small) member 11
chr14_+_34993240 2.94 ENST00000677647.1
signal recognition particle 54
chr14_-_89954518 2.88 ENST00000556005.1
ENST00000555872.5
EF-hand calcium binding domain 11
chr5_+_151020438 2.87 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
glutathione peroxidase 3
chr1_+_81306096 2.84 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr15_-_55917080 2.80 ENST00000506154.1
NEDD4 E3 ubiquitin protein ligase
chr7_-_16833411 2.75 ENST00000412973.1
anterior gradient 2, protein disulphide isomerase family member
chr21_-_26051023 2.75 ENST00000415997.1
amyloid beta precursor protein
chr3_+_161221280 2.70 ENST00000472947.5
ENST00000351193.7
ENST00000463518.5
NMD3 ribosome export adaptor
chr10_-_125881282 2.68 ENST00000284690.4
DEAH-box helicase 32 (putative)
chr5_+_120531464 2.63 ENST00000505123.5
proline rich 16
chrX_-_103686687 2.59 ENST00000441076.7
ENST00000422355.5
ENST00000442614.5
ENST00000451301.5
mortality factor 4 like 2
chr15_-_55917129 2.52 ENST00000338963.6
ENST00000508342.5
NEDD4 E3 ubiquitin protein ligase
chr19_-_10587219 2.52 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
adaptor related protein complex 1 subunit mu 2
chr11_+_112025968 2.51 ENST00000680411.1
dihydrolipoamide S-acetyltransferase
chr14_-_67412112 2.44 ENST00000216446.9
pleckstrin 2
chr1_+_115029823 2.43 ENST00000256592.3
thyroid stimulating hormone subunit beta
chr15_+_67125707 2.30 ENST00000540846.6
SMAD family member 3
chr17_+_47651061 2.20 ENST00000540627.5
karyopherin subunit beta 1
chr14_-_89954659 2.13 ENST00000555070.1
ENST00000316738.12
ENST00000538485.6
ENST00000556609.5
novel transcript
EF-hand calcium binding domain 11
chr14_+_88594406 2.13 ENST00000555900.5
zinc finger CCCH-type containing 14
chr8_-_140764386 2.13 ENST00000520151.5
ENST00000519024.5
ENST00000519465.5
protein tyrosine kinase 2
chr10_+_92593112 2.12 ENST00000260731.5
kinesin family member 11
chr8_-_48921419 2.10 ENST00000020945.4
snail family transcriptional repressor 2
chr14_+_19743571 2.08 ENST00000642117.2
olfactory receptor family 4 subfamily Q member 3
chr14_+_88594430 2.04 ENST00000406216.7
ENST00000557737.1
zinc finger CCCH-type containing 14
chr4_+_41935114 1.98 ENST00000508448.5
ENST00000513702.5
ENST00000325094.9
transmembrane protein 33
chr12_-_86256299 1.98 ENST00000552808.6
ENST00000547225.5
MGAT4 family member C
chr6_+_26087417 1.97 ENST00000357618.10
ENST00000309234.10
homeostatic iron regulator
chr17_-_42798680 1.94 ENST00000328434.8
cytochrome c oxidase assembly factor 3
chr19_+_53962925 1.94 ENST00000270458.4
calcium voltage-gated channel auxiliary subunit gamma 8
chr11_-_27700447 1.93 ENST00000356660.9
brain derived neurotrophic factor
chr14_+_88594395 1.92 ENST00000318308.10
zinc finger CCCH-type containing 14
chr12_-_86256267 1.84 ENST00000620241.4
MGAT4 family member C
chr17_-_44066595 1.83 ENST00000585388.2
ENST00000293406.8
LSM12 homolog
chrX_+_85003863 1.81 ENST00000373173.7
apolipoprotein O like
chr19_+_572529 1.74 ENST00000679472.1
ENST00000680552.1
ENST00000680065.1
ENST00000573216.5
basigin (Ok blood group)
chr19_-_51417791 1.73 ENST00000353836.9
sialic acid binding Ig like lectin 10
chr2_-_219399981 1.71 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
aspartyl aminopeptidase
chr6_+_113857333 1.70 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr14_+_103121457 1.61 ENST00000333007.8
TNF alpha induced protein 2
chr1_-_248277976 1.58 ENST00000641220.1
olfactory receptor family 2 subfamily T member 33
chr16_+_15395745 1.54 ENST00000287594.7
ENST00000396385.4
ENST00000568766.1
MPV17 mitochondrial inner membrane protein like
novel protein
chr5_+_141382702 1.53 ENST00000617050.1
ENST00000518325.2
protocadherin gamma subfamily A, 7
chr17_+_7252502 1.50 ENST00000570322.5
ENST00000576496.5
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr1_-_74733253 1.50 ENST00000417775.5
crystallin zeta
chr7_+_134843884 1.47 ENST00000445569.6
caldesmon 1
chr1_-_35641498 1.45 ENST00000373237.4
proteasome 20S subunit beta 2
chr9_+_12693327 1.43 ENST00000388918.10
tyrosinase related protein 1
chr2_+_102473219 1.40 ENST00000295269.5
solute carrier family 9 member A4
chr2_+_43774033 1.36 ENST00000260605.12
ENST00000406852.7
ENST00000398823.6
ENST00000605786.5
dynein cytoplasmic 2 light intermediate chain 1
chr4_-_152679984 1.34 ENST00000304385.8
ENST00000504064.1
transmembrane protein 154
chr4_+_70430487 1.33 ENST00000413702.5
mucin 7, secreted
chr11_+_35180279 1.32 ENST00000531873.5
CD44 molecule (Indian blood group)
chr5_-_56116946 1.31 ENST00000434982.2
ankyrin repeat domain 55
chr2_+_151357583 1.31 ENST00000243347.5
TNF alpha induced protein 6
chr11_-_113773668 1.29 ENST00000200135.8
zw10 kinetochore protein
chr9_+_108862255 1.29 ENST00000333999.5
actin like 7A
chr18_+_58341038 1.27 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr6_-_49744434 1.27 ENST00000433368.6
ENST00000354620.4
cysteine rich secretory protein 3
chr19_+_14583076 1.25 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chr12_+_26011713 1.23 ENST00000542004.5
Ras association domain family member 8
chr8_+_69492793 1.23 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr9_+_122370523 1.23 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr3_+_141738263 1.20 ENST00000480908.1
ENST00000393000.3
ENST00000273480.4
ring finger protein 7
chr3_-_194351290 1.19 ENST00000429275.1
ENST00000323830.4
carboxypeptidase N subunit 2
chr2_-_151261839 1.17 ENST00000331426.6
RNA binding motif protein 43
chr4_+_112647059 1.17 ENST00000511529.1
La ribonucleoprotein 7, transcriptional regulator
chr3_-_64019334 1.12 ENST00000480205.5
proteasome 26S subunit, non-ATPase 6
chr16_-_70801131 1.11 ENST00000261776.10
VAC14 component of PIKFYVE complex
chr1_+_119414931 1.11 ENST00000543831.5
ENST00000433745.5
ENST00000369416.4
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chrX_-_72239022 1.11 ENST00000373657.2
ENST00000334463.4
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr4_+_186069144 1.10 ENST00000513189.1
ENST00000296795.8
toll like receptor 3
chr9_+_122371014 1.06 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chrX_-_77969638 1.05 ENST00000458128.3
phosphoglycerate mutase family member 4
chr10_-_77637902 1.05 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr17_+_1771688 0.98 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr6_+_29461440 0.96 ENST00000396792.2
olfactory receptor family 2 subfamily H member 1
chr12_-_10826358 0.95 ENST00000240619.2
taste 2 receptor member 10
chr1_-_53945661 0.95 ENST00000194214.10
heat shock protein family B (small) member 11
chr2_-_17800195 0.94 ENST00000402989.5
ENST00000428868.1
structural maintenance of chromosomes 6
chr12_-_21941402 0.94 ENST00000326684.8
ENST00000682068.1
ENST00000621589.2
ENST00000261200.9
ENST00000683676.1
ATP binding cassette subfamily C member 9
chr1_-_34985288 0.91 ENST00000417456.1
ENST00000373337.3
novel protein
transmembrane protein 35B
chr11_-_63608542 0.90 ENST00000540943.1
phospholipase A and acyltransferase 3
chr1_-_13285154 0.89 ENST00000357367.6
ENST00000614831.1
PRAME family member 8
chr6_+_27957241 0.89 ENST00000244623.1
olfactory receptor family 2 subfamily B member 6
chr9_+_122371036 0.89 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr3_-_27456743 0.89 ENST00000295736.9
ENST00000428386.5
ENST00000428179.1
solute carrier family 4 member 7
chr2_+_11556337 0.88 ENST00000234142.9
growth regulating estrogen receptor binding 1
chr1_-_114695533 0.87 ENST00000520113.7
adenosine monophosphate deaminase 1
chr6_-_49744378 0.86 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr1_-_114695613 0.85 ENST00000369538.4
adenosine monophosphate deaminase 1
chr10_-_77637789 0.85 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr3_+_136930469 0.83 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr4_+_87832917 0.83 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr4_+_70397931 0.82 ENST00000399575.7
opiorphin prepropeptide
chr14_-_80231052 0.80 ENST00000557010.5
iodothyronine deiodinase 2
chr11_+_110429898 0.80 ENST00000260270.3
ferredoxin 1
chr18_+_6834473 0.78 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
Rho GTPase activating protein 28
chrX_+_15507302 0.77 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr2_+_176157293 0.77 ENST00000683222.1
homeobox D3
chr11_-_102780620 0.77 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chrX_+_71283577 0.75 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
non-POU domain containing octamer binding
chr8_-_90082871 0.72 ENST00000265431.7
calbindin 1
chr7_+_117014881 0.72 ENST00000422922.5
ENST00000432298.5
suppression of tumorigenicity 7
chr17_+_68515399 0.71 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr19_-_9107475 0.71 ENST00000641081.1
olfactory receptor family 7 subfamily G member 2
chrX_+_83861126 0.71 ENST00000621735.4
ENST00000329312.5
cylicin 1
chr7_-_83649097 0.70 ENST00000643230.2
semaphorin 3E
chr12_+_69359673 0.69 ENST00000548020.5
ENST00000549685.5
ENST00000247843.7
ENST00000552955.1
YEATS domain containing 4
chr11_+_73787853 0.68 ENST00000310614.12
ENST00000497094.6
ENST00000411840.6
ENST00000535277.5
ENST00000398483.7
ENST00000542303.5
mitochondrial ribosomal protein L48
chr10_+_52128343 0.68 ENST00000672084.1
protein kinase cGMP-dependent 1
chr6_+_29111560 0.68 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr11_-_18526885 0.67 ENST00000251968.4
ENST00000536719.5
tumor susceptibility 101
chr1_+_16367088 0.66 ENST00000471507.5
ENST00000401089.3
ENST00000401088.9
ENST00000492354.1
SUZ RNA binding domain containing 1
chr19_-_43465596 0.65 ENST00000244333.4
LY6/PLAUR domain containing 3
chr14_+_94026314 0.65 ENST00000203664.10
ENST00000553723.1
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr13_-_109786567 0.64 ENST00000375856.5
insulin receptor substrate 2
chr3_+_38496467 0.63 ENST00000453767.1
exo/endonuclease G
chr4_+_48831217 0.63 ENST00000510824.5
ENST00000425583.6
OCIA domain containing 1
chr2_-_164773733 0.62 ENST00000480873.1
cordon-bleu WH2 repeat protein like 1
chr12_-_56741535 0.62 ENST00000647707.1
novel protein
chr18_+_57352541 0.62 ENST00000324000.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr1_+_92832065 0.62 ENST00000315741.5
ribosomal protein L5
chr15_+_64387828 0.62 ENST00000261884.8
thyroid hormone receptor interactor 4
chr11_-_59845496 0.60 ENST00000257248.3
cobalamin binding intrinsic factor
chr7_-_13986439 0.58 ENST00000443608.5
ENST00000438956.5
ETS variant transcription factor 1
chr17_-_3292600 0.58 ENST00000615105.1
olfactory receptor family 3 subfamily A member 1
chr7_-_122098831 0.54 ENST00000681213.1
ENST00000679419.1
aminoadipate-semialdehyde synthase
chr14_+_21918161 0.54 ENST00000390439.2
T cell receptor alpha variable 13-2
chr18_-_13915531 0.51 ENST00000327606.4
melanocortin 2 receptor
chr14_+_96797304 0.51 ENST00000553683.2
ENST00000680538.1
ENST00000681195.1
ENST00000679727.1
ENST00000680509.1
ENST00000557222.6
ENST00000680683.1
ENST00000680335.1
ENST00000216639.8
ENST00000679736.1
ENST00000681176.1
ENST00000557352.2
ENST00000679903.1
ENST00000681419.1
ENST00000680849.1
ENST00000681493.1
ENST00000679770.1
ENST00000681355.1
ENST00000681344.1
VRK serine/threonine kinase 1
chr2_+_11534039 0.51 ENST00000381486.7
growth regulating estrogen receptor binding 1
chr19_-_4535221 0.50 ENST00000381848.7
ENST00000586133.1
perilipin 5
chr19_+_51225059 0.49 ENST00000436584.6
ENST00000421133.6
ENST00000262262.5
ENST00000391796.7
CD33 molecule
chr3_-_161105399 0.48 ENST00000652593.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr6_-_89217339 0.48 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr1_+_197268222 0.47 ENST00000367400.8
ENST00000638467.1
ENST00000367399.6
crumbs cell polarity complex component 1
chr5_+_141172637 0.47 ENST00000231137.6
protocadherin beta 7
chr14_-_36521149 0.47 ENST00000518149.5
NK2 homeobox 1
chr16_-_66730216 0.47 ENST00000569320.5
dynein cytoplasmic 1 light intermediate chain 2
chr10_-_77637721 0.47 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chr7_-_13986498 0.46 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETS variant transcription factor 1
chr11_+_122882683 0.46 ENST00000307257.10
ENST00000227349.7
junctional cadherin complex regulator
chr11_-_4697831 0.44 ENST00000641159.1
ENST00000396950.4
ENST00000532598.1
olfactory receptor family 51 subfamily C member 1 pseudogene
olfactory receptor family 51 subfamily E member 2
chr1_-_66801276 0.44 ENST00000304526.3
insulin like 5
chr6_+_154039333 0.44 ENST00000428397.6
opioid receptor mu 1
chr12_-_70754631 0.43 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
protein tyrosine phosphatase receptor type R
chr3_-_167380270 0.42 ENST00000392764.5
ENST00000675490.1
ENST00000474464.5
ENST00000392766.6
ENST00000485651.5
zinc finger B-box domain containing
chr4_+_174918355 0.41 ENST00000505141.5
ENST00000359240.7
ENST00000615367.4
ENST00000445694.5
ENST00000618444.1
ADAM metallopeptidase domain 29
chr2_-_26478032 0.40 ENST00000338581.10
ENST00000402415.8
otoferlin
chr4_-_102825526 0.40 ENST00000504211.5
ENST00000508476.5
ubiquitin conjugating enzyme E2 D3
chr12_-_118359105 0.39 ENST00000541186.5
ENST00000539872.5
TAO kinase 3
chr7_+_138460238 0.39 ENST00000343526.9
tripartite motif containing 24
chr12_-_57826295 0.39 ENST00000549039.5
CTD small phosphatase 2
chr2_+_161136901 0.37 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr12_-_10807286 0.36 ENST00000240615.3
taste 2 receptor member 8
chr7_+_120273129 0.35 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr16_+_16340328 0.35 ENST00000524823.6
novel member of the nuclear pore complex interacting protein NPIP gene family
chr11_-_89808575 0.35 ENST00000329758.5
tripartite motif containing 49

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 17.4 GO:0044111 development involved in symbiotic interaction(GO:0044111)
2.0 6.0 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
1.8 7.0 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
1.0 5.1 GO:2000542 negative regulation of gastrulation(GO:2000542)
1.0 2.9 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.8 4.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.8 4.7 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.7 2.9 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.7 2.2 GO:1904432 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.7 12.0 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.7 2.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.7 4.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.6 4.5 GO:0090166 Golgi disassembly(GO:0090166)
0.6 1.9 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.6 8.9 GO:0070986 left/right axis specification(GO:0070986)
0.6 3.9 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.6 3.3 GO:0070101 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.5 1.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.5 12.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 2.8 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.4 2.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.4 11.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 3.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.4 3.1 GO:0048478 replication fork protection(GO:0048478)
0.4 2.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.4 6.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.3 1.9 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.3 5.9 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.3 0.8 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.3 1.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.3 26.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3 3.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.2 1.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 0.7 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086) positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.2 1.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.2 2.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 0.8 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 0.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 2.4 GO:0034465 response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.2 0.5 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 0.7 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.2 1.2 GO:0060686 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.2 3.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 1.7 GO:0032264 IMP salvage(GO:0032264)
0.2 2.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 1.0 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 4.9 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 1.4 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.2 3.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 2.5 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 1.8 GO:0042407 cristae formation(GO:0042407)
0.1 0.6 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 1.7 GO:0046689 response to mercury ion(GO:0046689)
0.1 0.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 1.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 1.2 GO:0051601 exocyst localization(GO:0051601)
0.1 0.5 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.6 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 1.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 2.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 1.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 1.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.1 0.7 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 3.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.9 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 6.6 GO:0007032 endosome organization(GO:0007032)
0.1 0.7 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.3 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 2.4 GO:0033189 response to vitamin A(GO:0033189)
0.1 0.8 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 1.1 GO:0006702 androgen biosynthetic process(GO:0006702)
0.1 0.8 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 1.7 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.8 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.8 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.4 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 2.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 8.4 GO:0007498 mesoderm development(GO:0007498)
0.1 1.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
0.0 1.3 GO:0030728 ovulation(GO:0030728)
0.0 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 3.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.9 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.7 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.2 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0042420 catechol-containing compound catabolic process(GO:0019614) dopamine catabolic process(GO:0042420) catecholamine catabolic process(GO:0042424)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.8 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 1.6 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.2 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.4 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.7 GO:1901998 toxin transport(GO:1901998)
0.0 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 3.1 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 12.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
1.7 5.1 GO:0005588 collagen type V trimer(GO:0005588)
1.6 11.0 GO:0005610 laminin-5 complex(GO:0005610)
1.0 4.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.6 5.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.5 12.0 GO:0005685 U1 snRNP(GO:0005685)
0.4 1.3 GO:0097679 other organism cytoplasm(GO:0097679)
0.4 1.3 GO:0070939 Dsl1p complex(GO:0070939)
0.4 2.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.4 12.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4 2.2 GO:1990357 terminal web(GO:1990357)
0.3 3.1 GO:0031298 replication fork protection complex(GO:0031298)
0.3 2.9 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.3 2.8 GO:1990761 growth cone lamellipodium(GO:1990761)
0.3 1.8 GO:0061617 MICOS complex(GO:0061617)
0.3 6.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 4.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 2.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.9 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 0.7 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.2 4.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.2 3.0 GO:0043073 germ cell nucleus(GO:0043073)
0.2 5.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 1.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.4 GO:0030990 intraciliary transport particle(GO:0030990)
0.1 1.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 1.0 GO:0043203 axon hillock(GO:0043203)
0.1 1.5 GO:0030478 actin cap(GO:0030478)
0.1 2.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 3.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 1.9 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.2 GO:0000145 exocyst(GO:0000145)
0.1 2.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 2.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.7 GO:0002080 acrosomal membrane(GO:0002080)
0.1 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 7.6 GO:0031514 motile cilium(GO:0031514)
0.1 1.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 3.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 6.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 3.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 5.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 7.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.0 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 12.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
2.4 12.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.8 5.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.2 5.9 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
1.1 6.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.8 5.3 GO:0050815 phosphoserine binding(GO:0050815)
0.7 2.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.7 3.4 GO:1990254 keratin filament binding(GO:1990254)
0.7 3.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.6 3.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.6 2.5 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.6 4.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.6 3.9 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.5 3.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.5 2.9 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.5 4.9 GO:0005549 odorant binding(GO:0005549)
0.5 1.9 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.5 2.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.4 1.3 GO:0042806 fucose binding(GO:0042806)
0.4 2.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.4 1.5 GO:0070404 NADH binding(GO:0070404)
0.3 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 3.7 GO:0008430 selenium binding(GO:0008430)
0.3 1.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 2.8 GO:0051425 PTB domain binding(GO:0051425)
0.3 4.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 2.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 21.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 6.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 1.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 2.2 GO:0039706 co-receptor binding(GO:0039706)
0.2 4.5 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.7 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.2 1.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 6.1 GO:0008143 poly(A) binding(GO:0008143)
0.2 1.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.8 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 4.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.4 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.5 GO:0035473 lipase binding(GO:0035473)
0.1 1.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.1 GO:0008432 JUN kinase binding(GO:0008432)
0.1 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 5.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.5 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 1.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.7 GO:0005537 mannose binding(GO:0005537)
0.1 2.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 2.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 3.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 5.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 1.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 7.4 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.0 2.7 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 1.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.4 GO:0005507 copper ion binding(GO:0005507)
0.0 14.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0000149 SNARE binding(GO:0000149)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 1.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 4.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 4.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 13.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.1 NABA COLLAGENS Genes encoding collagen proteins
0.1 5.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 5.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 3.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.4 PID AURORA B PATHWAY Aurora B signaling
0.1 3.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 10.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.1 PID ATR PATHWAY ATR signaling pathway
0.1 3.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 4.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.3 4.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3 25.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 5.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 4.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 2.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 2.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 4.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 3.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 3.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 3.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.7 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 11.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 3.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 5.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.1 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.7 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 2.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 4.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 7.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 3.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport