ISMARA results: POU3F3

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for POU3F3_POU3F4

Z-value: 0.26

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Transcription factors associated with POU3F3_POU3F4

Gene Symbol	Gene ID	Gene Info
POU3F3 Ensembl NCBI GeneCards UniProt	ENSG00000198914.5	POU3F3
POU3F4 Ensembl NCBI GeneCards UniProt	ENSG00000196767.9	POU3F4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
POU3F4	hg38_v1_chrX_+_83508284_83508309	0.11	1.1e-01	Click!
POU3F3	hg38_v1_chr2_+_104854104_104854124	0.07	3.1e-01	Click!

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr15_-_45378519 Show fit	19.22	ENST00000558163.1 ENST00000396659.8 ENST00000675323.1 ENST00000558336.5	GATM Ensembl NCBI GeneCards UniProt Show fit	glycine amidinotransferase
chr14_-_20802402 Show fit	14.79	ENST00000412779.2	RNASE1 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 1, pancreatic
chr5_+_141382702 Show fit	14.34	ENST00000617050.1 ENST00000518325.2	PCDHGA7 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily A, 7
chr14_-_20802836 Show fit	13.89	ENST00000397967.5 ENST00000555698.5 ENST00000397970.4 ENST00000340900.3	RNASE1 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 1, pancreatic
chr3_-_58627596 Show fit	13.66	ENST00000474531.5 ENST00000465970.1	FAM107A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 107 member A
chr1_+_103655760 Show fit	12.75	ENST00000370083.9	AMY1A Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 1A
chr5_+_126423176 Show fit	10.25	ENST00000542322.5 ENST00000544396.5	GRAMD2B Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr1_-_103696209 Show fit	10.16	ENST00000330330.10	AMY1B Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 1B
chr1_+_103750406 Show fit	10.01	ENST00000370079.3	AMY1C Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 1C
chr1_+_103749898 Show fit	9.93	ENST00000622339.5	AMY1C Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 1C
chr5_+_126423122 Show fit	9.69	ENST00000515200.5	GRAMD2B Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr5_+_126423363 Show fit	9.59	ENST00000285689.8	GRAMD2B Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr2_+_188974364 Show fit	9.39	ENST00000304636.9 ENST00000317840.9	COL3A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type III alpha 1 chain
chr5_-_42811884 Show fit	9.31	ENST00000514985.6 ENST00000511224.5 ENST00000507920.5 ENST00000510965.1	SELENOP Ensembl NCBI GeneCards UniProt Show fit	selenoprotein P
chr1_+_103617427 Show fit	9.30	ENST00000423678.2 ENST00000414303.7	AMY2A Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 2A
chr3_+_159069252 Show fit	8.68	ENST00000640015.1 ENST00000476809.7 ENST00000485419.7	IQCJ-SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	IQCJ-SCHIP1 readthrough
chr6_-_46491956 Show fit	7.48	ENST00000306764.11	RCAN2 Ensembl NCBI GeneCards UniProt Show fit	regulator of calcineurin 2
chr17_-_40937641 Show fit	6.98	ENST00000209718.8	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23
chr8_-_90082871 Show fit	6.95	ENST00000265431.7	CALB1 Ensembl NCBI GeneCards UniProt Show fit	calbindin 1
chr17_+_3475959 Show fit	6.76	ENST00000263080.3	ASPA Ensembl NCBI GeneCards UniProt Show fit	aspartoacylase
chr5_+_141373878 Show fit	6.69	ENST00000517434.3 ENST00000610583.1	PCDHGA6 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily A, 6
chr12_-_111488538 Show fit	6.67	ENST00000389154.7	ATXN2 Ensembl NCBI GeneCards UniProt Show fit	ataxin 2
chr1_+_19596960 Show fit	6.63	ENST00000617872.4 ENST00000322753.7 ENST00000602662.1	MICOS10 Ensembl NCBI GeneCards UniProt Show fit NBL1 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial contact site and cristae organizing system subunit 10 NBL1, DAN family BMP antagonist
chr1_-_151372683 Show fit	6.52	ENST00000458566.5 ENST00000447402.7 ENST00000426705.6 ENST00000368868.10	SELENBP1 Ensembl NCBI GeneCards UniProt Show fit	selenium binding protein 1
chr17_-_40937445 Show fit	6.35	ENST00000436344.7 ENST00000485751.1	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23
chrX_+_47193796 Show fit	6.19	ENST00000442035.5 ENST00000335972.11 ENST00000457753.5	UBA1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin like modifier activating enzyme 1
chr17_-_68955332 Show fit	6.05	ENST00000269080.6 ENST00000615593.4 ENST00000586539.6 ENST00000430352.6	ABCA8 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 8
chr16_-_10559135 Show fit	5.92	ENST00000536829.1	EMP2 Ensembl NCBI GeneCards UniProt Show fit	epithelial membrane protein 2
chr2_+_200305873 Show fit	5.81	ENST00000439084.5 ENST00000409718.5	SPATS2L Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated serine rich 2 like
chr2_-_100417608 Show fit	5.64	ENST00000264249.8	CHST10 Ensembl NCBI GeneCards UniProt Show fit	carbohydrate sulfotransferase 10
chr19_+_735026 Show fit	5.60	ENST00000592155.5 ENST00000590161.2	PALM Ensembl NCBI GeneCards UniProt Show fit	paralemmin
chr3_+_35680994 Show fit	5.40	ENST00000441454.5	ARPP21 Ensembl NCBI GeneCards UniProt Show fit	cAMP regulated phosphoprotein 21
chr1_+_103571077 Show fit	5.15	ENST00000610648.1	AMY2B Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 2B
chr3_+_148791058 Show fit	5.14	ENST00000491148.5	CPB1 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase B1
chr2_+_200306048 Show fit	5.05	ENST00000409988.7 ENST00000409385.5	SPATS2L Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated serine rich 2 like
chr17_-_63911236 Show fit	4.93	ENST00000438387.6 ENST00000346606.10 ENST00000309894.6 ENST00000561003.5 ENST00000450719.3 ENST00000259003.14	CSHL1 Ensembl NCBI GeneCards UniProt Show fit	chorionic somatomammotropin hormone like 1
chr2_-_55010348 Show fit	4.83	ENST00000394609.6	RTN4 Ensembl NCBI GeneCards UniProt Show fit	reticulon 4
chrX_+_23664251 Show fit	4.78	ENST00000379349.5	PRDX4 Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin 4
chr8_-_66178455 Show fit	4.65	ENST00000276571.5	CRH Ensembl NCBI GeneCards UniProt Show fit	corticotropin releasing hormone
chr18_+_49562049 Show fit	4.60	ENST00000261292.9 ENST00000427224.6 ENST00000580036.5	LIPG Ensembl NCBI GeneCards UniProt Show fit	lipase G, endothelial type
chr6_-_52994248 Show fit	4.36	ENST00000457564.1 ENST00000370960.5	GSTA4 Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase alpha 4
chr12_-_91179472 Show fit	4.26	ENST00000550099.5 ENST00000546391.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr15_-_52295792 Show fit	4.12	ENST00000261839.12	MYO5C Ensembl NCBI GeneCards UniProt Show fit	myosin VC
chr5_+_141121793 Show fit	3.87	ENST00000194152.4	PCDHB4 Ensembl NCBI GeneCards UniProt Show fit	protocadherin beta 4
chr16_-_70801131 Show fit	3.85	ENST00000261776.10	VAC14 Ensembl NCBI GeneCards UniProt Show fit	VAC14 component of PIKFYVE complex
chr1_+_212432891 Show fit	3.65	ENST00000366988.5	NENF Ensembl NCBI GeneCards UniProt Show fit	neudesin neurotrophic factor
chr12_-_91180365 Show fit	3.61	ENST00000547937.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr3_-_127736329 Show fit	3.60	ENST00000398101.7	MGLL Ensembl NCBI GeneCards UniProt Show fit	monoglyceride lipase
chr18_-_36067524 Show fit	3.57	ENST00000590898.5 ENST00000357384.8 ENST00000399022.9 ENST00000588737.5	RPRD1A Ensembl NCBI GeneCards UniProt Show fit	regulation of nuclear pre-mRNA domain containing 1A
chr10_+_112950240 Show fit	3.49	ENST00000627217.3 ENST00000534894.5 ENST00000538897.5 ENST00000536810.5 ENST00000355995.8 ENST00000542695.5 ENST00000543371.5	TCF7L2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr10_-_88952763 Show fit	3.41	ENST00000224784.10	ACTA2 Ensembl NCBI GeneCards UniProt Show fit	actin alpha 2, smooth muscle
chr5_-_79514127 Show fit	3.39	ENST00000334082.11	HOMER1 Ensembl NCBI GeneCards UniProt Show fit	homer scaffold protein 1
chr5_-_160852200 Show fit	3.37	ENST00000327245.10	ATP10B Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 10B (putative)
chr15_-_29821473 Show fit	3.36	ENST00000400011.6	TJP1 Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 1
chr4_-_86360071 Show fit	3.19	ENST00000641677.1 ENST00000639234.1 ENST00000641553.1 ENST00000641826.1 ENST00000641537.1 ENST00000395169.9 ENST00000641408.1 ENST00000638225.1 ENST00000641052.1	MAPK10 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 10
chr10_+_112950452 Show fit	3.11	ENST00000369397.8	TCF7L2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr6_+_125153793 Show fit	3.10	ENST00000527711.5	TPD52L1 Ensembl NCBI GeneCards UniProt Show fit	TPD52 like 1
chr5_-_11588842 Show fit	3.04	ENST00000503622.5	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr5_-_134174765 Show fit	2.96	ENST00000520417.1	SKP1 Ensembl NCBI GeneCards UniProt Show fit	S-phase kinase associated protein 1
chr17_-_66220630 Show fit	2.91	ENST00000585162.1	APOH Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein H
chr3_-_149657996 Show fit	2.88	ENST00000360632.8 ENST00000467467.5 ENST00000460517.1	WWTR1 Ensembl NCBI GeneCards UniProt Show fit	WW domain containing transcription regulator 1
chr4_+_186069144 Show fit	2.80	ENST00000513189.1 ENST00000296795.8	TLR3 Ensembl NCBI GeneCards UniProt Show fit	toll like receptor 3
chr1_-_1361777 Show fit	2.77	ENST00000477278.3	MXRA8 Ensembl NCBI GeneCards UniProt Show fit	matrix remodeling associated 8
chr12_-_91179355 Show fit	2.71	ENST00000550563.5 ENST00000546370.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr17_-_40822604 Show fit	2.68	ENST00000269576.6 ENST00000635956.2	KRT10 Ensembl NCBI GeneCards UniProt Show fit	keratin 10
chr5_+_36608146 Show fit	2.67	ENST00000381918.4 ENST00000513646.1	SLC1A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 3
chr7_+_48924559 Show fit	2.65	ENST00000650262.1	CDC14C Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14C
chr2_-_166149204 Show fit	2.62	ENST00000635750.1	SCN1A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 1
chr7_-_14841267 Show fit	2.61	ENST00000406247.7 ENST00000399322.7	DGKB Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase beta
chr5_-_11589019 Show fit	2.61	ENST00000511377.5	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr3_-_186109067 Show fit	2.59	ENST00000306376.10	ETV5 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 5
chr2_-_166149120 Show fit	2.55	ENST00000641575.1 ENST00000641603.1	SCN1A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 1
chr12_+_18262730 Show fit	2.55	ENST00000675017.1	PIK3C2G Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr6_+_29461440 Show fit	2.55	ENST00000396792.2	OR2H1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily H member 1
chr9_-_14322320 Show fit	2.50	ENST00000606230.2	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr12_-_91179517 Show fit	2.45	ENST00000551354.1	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr9_-_14180779 Show fit	2.43	ENST00000380924.1 ENST00000543693.5	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr12_-_102480552 Show fit	2.39	ENST00000337514.11 ENST00000307046.8	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr11_-_57237183 Show fit	2.37	ENST00000606794.1	APLNR Ensembl NCBI GeneCards UniProt Show fit	apelin receptor
chr2_-_182242031 Show fit	2.29	ENST00000358139.6	PDE1A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1A
chr17_+_41966787 Show fit	2.25	ENST00000393892.8 ENST00000587679.1	CNP Ensembl NCBI GeneCards UniProt Show fit	2',3'-cyclic nucleotide 3' phosphodiesterase
chr6_+_125153846 Show fit	2.21	ENST00000528193.5	TPD52L1 Ensembl NCBI GeneCards UniProt Show fit	TPD52 like 1
chr8_-_85341659 Show fit	2.18	ENST00000522389.5	CA1 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 1
chr19_-_43619591 Show fit	2.17	ENST00000598676.1 ENST00000300811.8	ZNF428 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 428
chr19_-_8308287 Show fit	2.17	ENST00000537716.6 ENST00000301458.10	CD320 Ensembl NCBI GeneCards UniProt Show fit	CD320 molecule
chr12_-_10172117 Show fit	2.14	ENST00000545927.5 ENST00000309539.8 ENST00000432556.6 ENST00000544577.5	OLR1 Ensembl NCBI GeneCards UniProt Show fit	oxidized low density lipoprotein receptor 1
chr10_+_69801874 Show fit	2.12	ENST00000357811.8	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr22_+_44752552 Show fit	2.11	ENST00000389774.6 ENST00000356099.11 ENST00000396119.6 ENST00000336963.8 ENST00000412433.5	ARHGAP8 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 8
chr5_+_93583212 Show fit	2.08	ENST00000327111.8	NR2F1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group F member 1
chr1_-_48400826 Show fit	2.07	ENST00000371841.1	SPATA6 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 6
chr7_+_100428782 Show fit	2.07	ENST00000414441.5	MEPCE Ensembl NCBI GeneCards UniProt Show fit	methylphosphate capping enzyme
chr21_-_41926680 Show fit	2.07	ENST00000329623.11	C2CD2 Ensembl NCBI GeneCards UniProt Show fit	C2 calcium dependent domain containing 2
chr6_+_36676455 Show fit	2.03	ENST00000615513.4	CDKN1A Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 1A
chr5_+_140875299 Show fit	2.01	ENST00000613593.1 ENST00000398631.3	PCDHA12 Ensembl NCBI GeneCards UniProt Show fit	protocadherin alpha 12
chr4_-_167234426 Show fit	2.01	ENST00000541354.5 ENST00000509854.5 ENST00000512681.5 ENST00000357545.9 ENST00000510741.5 ENST00000510403.5	SPOCK3 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr12_-_11310420 Show fit	2.00	ENST00000621732.4 ENST00000445719.2 ENST00000279575.7	PRB4 Ensembl NCBI GeneCards UniProt Show fit	proline rich protein BstNI subfamily 4
chr12_-_84892120 Show fit	1.98	ENST00000680379.1	SLC6A15 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 15
chr12_-_102480638 Show fit	1.96	ENST00000392904.5	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr2_-_182522703 Show fit	1.95	ENST00000410103.1	PDE1A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1A
chr5_+_141968886 Show fit	1.93	ENST00000347642.7	RNF14 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 14
chr8_-_63026179 Show fit	1.93	ENST00000677919.1	GGH Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyl hydrolase
chr2_-_58241259 Show fit	1.92	ENST00000481670.2 ENST00000403676.5 ENST00000427708.6 ENST00000403295.7 ENST00000233741.9 ENST00000446381.5 ENST00000417361.1 ENST00000402135.7 ENST00000449070.5	FANCL Ensembl NCBI GeneCards UniProt Show fit	FA complementation group L
chr2_+_200305976 Show fit	1.91	ENST00000358677.9	SPATS2L Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated serine rich 2 like
chr10_+_69801892 Show fit	1.89	ENST00000398978.8 ENST00000645393.2 ENST00000354547.7 ENST00000674121.1 ENST00000673842.1 ENST00000520267.5	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr6_-_136526177 Show fit	1.83	ENST00000617204.4	MAP7 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 7
chr7_+_116953379 Show fit	1.79	ENST00000393449.5	ST7 Ensembl NCBI GeneCards UniProt Show fit	suppression of tumorigenicity 7
chr1_-_193186599 Show fit	1.76	ENST00000367434.5	B3GALT2 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-galactosyltransferase 2
chr1_+_27773189 Show fit	1.74	ENST00000373943.9 ENST00000440806.2	STX12 Ensembl NCBI GeneCards UniProt Show fit	syntaxin 12
chr10_+_93757831 Show fit	1.73	ENST00000629035.2	LGI1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich glioma inactivated 1
chr2_-_174846405 Show fit	1.70	ENST00000409597.5 ENST00000413882.6	CHN1 Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr15_-_74366178 Show fit	1.68	ENST00000450547.1 ENST00000358632.8	CYP11A1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 11 subfamily A member 1
chr2_-_113235443 Show fit	1.68	ENST00000465084.1	PAX8 Ensembl NCBI GeneCards UniProt Show fit	paired box 8
chr16_+_56191476 Show fit	1.63	ENST00000262493.12	GNAO1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha o1
chr8_-_27837765 Show fit	1.58	ENST00000521226.2 ENST00000301905.9	PBK Ensembl NCBI GeneCards UniProt Show fit	PDZ binding kinase
chr14_-_80231052 Show fit	1.58	ENST00000557010.5	DIO2 Ensembl NCBI GeneCards UniProt Show fit	iodothyronine deiodinase 2
chr6_-_47309898 Show fit	1.54	ENST00000296861.2	TNFRSF21 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 21
chr1_+_101237009 Show fit	1.51	ENST00000305352.7	S1PR1 Ensembl NCBI GeneCards UniProt Show fit	sphingosine-1-phosphate receptor 1
chr17_-_63918817 Show fit	1.50	ENST00000458650.6 ENST00000351388.8 ENST00000342364.8 ENST00000617086.1 ENST00000323322.10 ENST00000392824.8	GH1 Ensembl NCBI GeneCards UniProt Show fit CSHL1 Ensembl NCBI GeneCards UniProt Show fit	growth hormone 1 chorionic somatomammotropin hormone like 1
chr2_+_33134620 Show fit	1.49	ENST00000402934.5 ENST00000404525.5 ENST00000407925.5	LTBP1 Ensembl NCBI GeneCards UniProt Show fit	latent transforming growth factor beta binding protein 1
chr3_+_40100007 Show fit	1.46	ENST00000539167.2	MYRIP Ensembl NCBI GeneCards UniProt Show fit	myosin VIIA and Rab interacting protein
chr11_+_31650024 Show fit	1.46	ENST00000638317.1	ELP4 Ensembl NCBI GeneCards UniProt Show fit	elongator acetyltransferase complex subunit 4
chr6_+_36676489 Show fit	1.44	ENST00000448526.6	CDKN1A Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 1A
chr12_-_102480604 Show fit	1.43	ENST00000392905.7	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr2_+_33134579 Show fit	1.42	ENST00000418533.6	LTBP1 Ensembl NCBI GeneCards UniProt Show fit	latent transforming growth factor beta binding protein 1
chr20_+_49936371 Show fit	1.39	ENST00000244061.6 ENST00000625177.3 ENST00000622920.1	RNF114 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 114
chr17_-_63873676 Show fit	1.38	ENST00000613718.3 ENST00000392886.7 ENST00000345366.8 ENST00000336844.9 ENST00000560142.5	CSH2 Ensembl NCBI GeneCards UniProt Show fit	chorionic somatomammotropin hormone 2
chr4_-_99352754 Show fit	1.32	ENST00000639454.1	ADH1B Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 1B (class I), beta polypeptide
chr14_+_69191475 Show fit	1.30	ENST00000409018.7 ENST00000409014.5 ENST00000409675.5	EXD2 Ensembl NCBI GeneCards UniProt Show fit	exonuclease 3'-5' domain containing 2
chr16_+_83971451 Show fit	1.28	ENST00000565691.5	NECAB2 Ensembl NCBI GeneCards UniProt Show fit	N-terminal EF-hand calcium binding protein 2
chr5_+_141402764 Show fit	1.26	ENST00000573521.2 ENST00000616887.1	PCDHGA9 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily A, 9
chr4_-_167234579 Show fit	1.26	ENST00000502330.5 ENST00000357154.7 ENST00000421836.6	SPOCK3 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr6_-_136526472 Show fit	1.25	ENST00000454590.5 ENST00000432797.6	MAP7 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 7
chr4_-_144019287 Show fit	1.22	ENST00000638448.1 ENST00000513128.5 ENST00000506516.6 ENST00000429670.3 ENST00000502664.6	GYPB Ensembl NCBI GeneCards UniProt Show fit	glycophorin B (MNS blood group)
chr16_+_30053123 Show fit	1.21	ENST00000395248.6 ENST00000575627.5 ENST00000566897.6 ENST00000568435.6 ENST00000338110.11 ENST00000562240.1	ENSG00000285043.3 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr14_-_25010604 Show fit	1.14	ENST00000550887.5	STXBP6 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 6
chr22_-_30246739 Show fit	1.12	ENST00000403987.3 ENST00000249075.4	LIF Ensembl NCBI GeneCards UniProt Show fit	LIF interleukin 6 family cytokine
chr17_-_10549612 Show fit	1.09	ENST00000532183.6 ENST00000397183.6 ENST00000420805.1	MYH2 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr11_-_28108109 Show fit	1.08	ENST00000263181.7	KIF18A Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 18A
chr16_-_21303036 Show fit	1.06	ENST00000219599.8 ENST00000576703.5	CRYM Ensembl NCBI GeneCards UniProt Show fit	crystallin mu
chr6_-_11778781 Show fit	1.05	ENST00000414691.8 ENST00000229583.9	ADTRP Ensembl NCBI GeneCards UniProt Show fit	androgen dependent TFPI regulating protein
chr10_+_112950586 Show fit	1.05	ENST00000355717.9 ENST00000352065.10 ENST00000369395.6 ENST00000545257.6	TCF7L2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr4_-_99352730 Show fit	1.05	ENST00000510055.5 ENST00000515683.6 ENST00000511397.3	ADH1C Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 1C (class I), gamma polypeptide
chr4_+_145482761 Show fit	1.04	ENST00000507367.1 ENST00000394092.6 ENST00000515385.1	SMAD1 Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 1
chr7_-_50561048 Show fit	1.03	ENST00000380984.4 ENST00000357936.9 ENST00000426377.5 ENST00000615193.4 ENST00000617822.4 ENST00000622873.4	DDC Ensembl NCBI GeneCards UniProt Show fit	dopa decarboxylase
chr4_+_174918400 Show fit	1.01	ENST00000404450.8 ENST00000514159.1	ADAM29 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 29
chr11_+_22338333 Show fit	1.01	ENST00000263160.4	SLC17A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 member 6
chr7_+_134843884 Show fit	0.98	ENST00000445569.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr14_+_70452161 Show fit	0.98	ENST00000603540.2	ADAM21 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 21
chr4_-_139084289 Show fit	0.97	ENST00000510408.5 ENST00000379549.7 ENST00000358635.7	ELF2 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 2
chr5_+_141966820 Show fit	0.95	ENST00000513019.5 ENST00000394519.5 ENST00000356143.5	RNF14 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 14
chr14_-_74493275 Show fit	0.95	ENST00000541064.5	NPC2 Ensembl NCBI GeneCards UniProt Show fit	NPC intracellular cholesterol transporter 2
chr11_+_120236635 Show fit	0.88	ENST00000260264.8	POU2F3 Ensembl NCBI GeneCards UniProt Show fit	POU class 2 homeobox 3
chr1_+_196774813 Show fit	0.87	ENST00000471440.6 ENST00000391985.7 ENST00000617219.1 ENST00000367425.9	CFHR3 Ensembl NCBI GeneCards UniProt Show fit	complement factor H related 3
chr14_+_21280077 Show fit	0.86	ENST00000400017.7	RPGRIP1 Ensembl NCBI GeneCards UniProt Show fit	RPGR interacting protein 1
chr8_-_85341705 Show fit	0.86	ENST00000517618.5	CA1 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 1
chrX_-_124963768 Show fit	0.86	ENST00000371130.7 ENST00000422452.2	TENM1 Ensembl NCBI GeneCards UniProt Show fit	teneurin transmembrane protein 1
chr6_-_131000722 Show fit	0.86	ENST00000528282.5	EPB41L2 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr12_+_27022543 Show fit	0.86	ENST00000546323.5 ENST00000282892.4	MED21 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 21
chr3_+_130850585 Show fit	0.83	ENST00000505330.5 ENST00000504381.5 ENST00000507488.6	ATP2C1 Ensembl NCBI GeneCards UniProt Show fit	ATPase secretory pathway Ca2+ transporting 1
chr6_+_30163188 Show fit	0.83	ENST00000619857.4	TRIM15 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 15
chr1_-_216805367 Show fit	0.81	ENST00000360012.7	ESRRG Ensembl NCBI GeneCards UniProt Show fit	estrogen related receptor gamma
chr9_+_34458752 Show fit	0.79	ENST00000614641.4 ENST00000242317.9 ENST00000437363.5	DNAI1 Ensembl NCBI GeneCards UniProt Show fit	dynein axonemal intermediate chain 1
chrX_-_112840815 Show fit	0.76	ENST00000304758.5 ENST00000371959.9	AMOT Ensembl NCBI GeneCards UniProt Show fit	angiomotin
chr5_+_141330494 Show fit	0.75	ENST00000517417.3 ENST00000378105.4	PCDHGA1 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily A, 1
chr19_+_38647679 Show fit	0.73	ENST00000390009.7 ENST00000589528.1	ACTN4 Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 4
chr17_-_52158678 Show fit	0.73	ENST00000451037.7	CA10 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 10
chr1_-_109393197 Show fit	0.72	ENST00000538502.5 ENST00000482236.5	SORT1 Ensembl NCBI GeneCards UniProt Show fit	sortilin 1
chr17_+_7252502 Show fit	0.71	ENST00000570322.5 ENST00000576496.5 ENST00000574841.2	ELP5 Ensembl NCBI GeneCards UniProt Show fit	elongator acetyltransferase complex subunit 5
chrX_-_81201886 Show fit	0.71	ENST00000451455.1 ENST00000358130.7 ENST00000436386.5	HMGN5 Ensembl NCBI GeneCards UniProt Show fit	high mobility group nucleosome binding domain 5
chrX_+_135893703 Show fit	0.71	ENST00000370709.4	SAGE1 Ensembl NCBI GeneCards UniProt Show fit	sarcoma antigen 1
chr19_+_38647614 Show fit	0.71	ENST00000252699.7 ENST00000424234.7 ENST00000440400.2	ACTN4 Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 4
chr12_-_10909562 Show fit	0.71	ENST00000390677.2	TAS2R13 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 13
chr7_+_106865474 Show fit	0.70	ENST00000359195.3	PIK3CG Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr17_-_10549694 Show fit	0.69	ENST00000622564.4	MYH2 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr12_-_70754631 Show fit	0.69	ENST00000440835.6 ENST00000549308.5 ENST00000550661.1 ENST00000378778.5	PTPRR Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type R
chr10_-_125881282 Show fit	0.68	ENST00000284690.4	DHX32 Ensembl NCBI GeneCards UniProt Show fit	DEAH-box helicase 32 (putative)
chr6_-_136525961 Show fit	0.68	ENST00000438100.6	MAP7 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 7
chr14_-_74493322 Show fit	0.68	ENST00000553490.5 ENST00000557510.5	NPC2 Ensembl NCBI GeneCards UniProt Show fit	NPC intracellular cholesterol transporter 2
chr9_+_21440437 Show fit	0.67	ENST00000276927.3	IFNA1 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 1
chr13_-_70108441 Show fit	0.65	ENST00000377844.9 ENST00000545028.2	KLHL1 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 1
chr4_-_16083714 Show fit	0.65	ENST00000508167.5	PROM1 Ensembl NCBI GeneCards UniProt Show fit	prominin 1
chr4_-_16083695 Show fit	0.65	ENST00000510224.5	PROM1 Ensembl NCBI GeneCards UniProt Show fit	prominin 1
chr3_+_112086335 Show fit	0.63	ENST00000431717.6 ENST00000480282.5	C3orf52 Ensembl NCBI GeneCards UniProt Show fit	chromosome 3 open reading frame 52
chr10_-_92243246 Show fit	0.62	ENST00000412050.8 ENST00000614585.4	CPEB3 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic polyadenylation element binding protein 3
chr20_+_1118590 Show fit	0.62	ENST00000246015.8 ENST00000335877.11	PSMF1 Ensembl NCBI GeneCards UniProt Show fit	proteasome inhibitor subunit 1
chr3_-_52897541 Show fit	0.61	ENST00000355083.11 ENST00000504329.1	STIMATE Ensembl NCBI GeneCards UniProt Show fit STIMATE-MUSTN1 Ensembl NCBI GeneCards UniProt Show fit	STIM activating enhancer STIMATE-MUSTN1 readthrough
chr5_-_161546708 Show fit	0.60	ENST00000393959.6	GABRB2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit beta2
chr19_+_35995176 Show fit	0.59	ENST00000378887.4	SDHAF1 Ensembl NCBI GeneCards UniProt Show fit	succinate dehydrogenase complex assembly factor 1
chr5_+_140794832 Show fit	0.57	ENST00000378132.2 ENST00000526136.2 ENST00000520672.2	PCDHA2 Ensembl NCBI GeneCards UniProt Show fit	protocadherin alpha 2
chr1_-_179143044 Show fit	0.56	ENST00000504405.5 ENST00000512653.5 ENST00000344730.7	ABL2 Ensembl NCBI GeneCards UniProt Show fit	ABL proto-oncogene 2, non-receptor tyrosine kinase
chrX_+_54807599 Show fit	0.56	ENST00000375053.6 ENST00000627068.2 ENST00000375068.6 ENST00000347546.8	MAGED2 Ensembl NCBI GeneCards UniProt Show fit	MAGE family member D2
chr13_+_101489940 Show fit	0.55	ENST00000376162.7	ITGBL1 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta like 1
chr14_+_21868822 Show fit	0.55	ENST00000390436.2	TRAV13-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 13-1
chr19_+_47745534 Show fit	0.54	ENST00000246802.10	NOP53 Ensembl NCBI GeneCards UniProt Show fit	NOP53 ribosome biogenesis factor
chr9_-_92536031 Show fit	0.53	ENST00000344604.9 ENST00000375540.5	ECM2 Ensembl NCBI GeneCards UniProt Show fit	extracellular matrix protein 2
chr9_-_15472732 Show fit	0.52	ENST00000481862.1	PSIP1 Ensembl NCBI GeneCards UniProt Show fit	PC4 and SFRS1 interacting protein 1
chr19_-_18522051 Show fit	0.52	ENST00000262809.9	ELL Ensembl NCBI GeneCards UniProt Show fit	elongation factor for RNA polymerase II
chrX_+_15507302 Show fit	0.52	ENST00000342014.6	BMX Ensembl NCBI GeneCards UniProt Show fit	BMX non-receptor tyrosine kinase
chr3_+_189789734 Show fit	0.51	ENST00000437221.5 ENST00000392463.6 ENST00000392461.7 ENST00000449992.5 ENST00000456148.1	TP63 Ensembl NCBI GeneCards UniProt Show fit	tumor protein p63
chr12_-_91058016 Show fit	0.51	ENST00000266719.4	KERA Ensembl NCBI GeneCards UniProt Show fit	keratocan

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	6.8	GO:0006533	aspartate catabolic process(GO:0006533)
1.7	6.6	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
1.6	9.4	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
1.6	4.7	GO:0071314	positive regulation of corticotropin secretion(GO:0051461) positive regulation of cortisol secretion(GO:0051464) negative regulation of glucagon secretion(GO:0070093) cellular response to cocaine(GO:0071314)
1.3	9.3	GO:0044245	polysaccharide digestion(GO:0044245)
1.3	19.2	GO:0006600	creatine metabolic process(GO:0006600)
1.2	4.8	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
1.2	9.3	GO:0001887	selenium compound metabolic process(GO:0001887)
1.2	5.8	GO:1904075	regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
1.2	4.6	GO:0010986	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
1.0	13.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.9	3.6	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.9	6.9	GO:0035502	metanephric part of ureteric bud development(GO:0035502)
0.8	3.4	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.8	5.6	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.7	2.8	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.7	3.4	GO:0072143	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.7	3.4	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.6	7.7	GO:0044334	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.6	5.9	GO:0070836	caveola assembly(GO:0070836)
0.5	1.5	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.5	1.5	GO:0003241	growth involved in heart morphogenesis(GO:0003241) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.5	4.8	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.5	1.9	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.5	6.1	GO:0042908	xenobiotic transport(GO:0042908)
0.5	3.6	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4	4.9	GO:2000795	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4	1.7	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.4	6.7	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.4	2.9	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.4	2.9	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.4	3.6	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.4	1.1	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.4	2.6	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3	28.1	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.3	1.0	GO:0052314	serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314)
0.3	3.7	GO:0032099	negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.3	3.0	GO:0010265	SCF complex assembly(GO:0010265)
0.3	1.6	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.3	1.3	GO:1904021	regulation of G-protein coupled receptor internalization(GO:1904020) negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.3	4.6	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3	2.1	GO:0040031	snRNA modification(GO:0040031)
0.3	3.5	GO:0090400	stress-induced premature senescence(GO:0090400)
0.3	0.8	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.3	2.7	GO:0009449	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2	2.0	GO:0035524	proline transmembrane transport(GO:0035524)
0.2	1.4	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.2	2.4	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.2	0.7	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.2	3.5	GO:0034391	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.2	1.5	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.2	3.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	0.6	GO:1900365	positive regulation of mRNA polyadenylation(GO:1900365)
0.2	0.6	GO:0034553	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2	1.8	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2	1.3	GO:2000768	glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.2	0.5	GO:1903006	regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.2	30.1	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2	1.0	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2	2.2	GO:0015889	cobalamin transport(GO:0015889)
0.2	2.7	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.2	2.8	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.2	2.3	GO:0001778	plasma membrane repair(GO:0001778)
0.1	1.0	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	4.4	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1	1.6	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1	0.8	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	1.6	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	3.4	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	5.7	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1	1.5	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.1	13.8	GO:0070268	cornification(GO:0070268)
0.1	1.1	GO:0051601	exocyst localization(GO:0051601)
0.1	0.8	GO:0036158	outer dynein arm assembly(GO:0036158)
0.1	0.6	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.4	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
0.1	0.5	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1	0.5	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	0.7	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	0.8	GO:0001865	NK T cell differentiation(GO:0001865)
0.1	0.5	GO:0043697	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1	14.9	GO:0007586	digestion(GO:0007586)
0.1	1.1	GO:0006554	lysine catabolic process(GO:0006554) thyroid hormone transport(GO:0070327)
0.1	0.9	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	2.1	GO:0044458	motile cilium assembly(GO:0044458)
0.1	0.2	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	2.6	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	1.0	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1	4.0	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	2.8	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.1	2.6	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1	3.5	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	0.3	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.1	1.7	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.1	3.8	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	1.1	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1	1.7	GO:0033344	cholesterol efflux(GO:0033344)
0.1	0.5	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	1.1	GO:0072520	seminiferous tubule development(GO:0072520)
0.1	5.3	GO:0060997	dendritic spine morphogenesis(GO:0060997)
0.1	0.2	GO:0043091	regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.1	0.8	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	1.7	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	1.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.5	GO:0006069	ethanol oxidation(GO:0006069)
0.0	0.5	GO:0097070	ductus arteriosus closure(GO:0097070)
0.0	0.4	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.9	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.2	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.0	1.3	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	2.3	GO:0021762	substantia nigra development(GO:0021762)
0.0	0.5	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.9	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	1.6	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.3	GO:0022605	ovarian cumulus expansion(GO:0001550) oogenesis stage(GO:0022605) fused antrum stage(GO:0048165)
0.0	0.7	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.5	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0061743	motor learning(GO:0061743)
0.0	0.3	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	4.9	GO:0046330	positive regulation of JNK cascade(GO:0046330)
0.0	0.5	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.2	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	1.9	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.5	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.4	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	4.4	GO:0034605	cellular response to heat(GO:0034605)
0.0	2.6	GO:0006970	response to osmotic stress(GO:0006970)
0.0	0.3	GO:0023058	adaptation of signaling pathway(GO:0023058)
0.0	5.6	GO:0016051	carbohydrate biosynthetic process(GO:0016051)
0.0	0.7	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
0.0	0.8	GO:0010863	positive regulation of phospholipase C activity(GO:0010863)
0.0	1.7	GO:1901799	negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0	0.3	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.7	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	1.9	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	1.2	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.7	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	1.5	GO:0050806	positive regulation of synaptic transmission(GO:0050806)
0.0	0.4	GO:0046850	regulation of bone remodeling(GO:0046850)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	4.0	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.1	3.4	GO:0030485	smooth muscle contractile fiber(GO:0030485)
1.0	13.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.7	5.8	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.7	9.4	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.7	3.5	GO:0070557	PCNA-p21 complex(GO:0070557)
0.7	2.1	GO:0097224	sperm connecting piece(GO:0097224)
0.7	4.7	GO:0043196	varicosity(GO:0043196)
0.6	7.7	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.6	11.9	GO:0031089	platelet dense granule lumen(GO:0031089)
0.5	1.5	GO:0070195	growth hormone receptor complex(GO:0070195)
0.5	3.0	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.5	3.8	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.5	2.3	GO:0005826	actomyosin contractile ring(GO:0005826)
0.4	29.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.3	5.6	GO:0032591	dendritic spine membrane(GO:0032591)
0.2	4.9	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	0.7	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2	6.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.2	2.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.2	4.8	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.2	1.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.2	4.4	GO:0043194	axon initial segment(GO:0043194)
0.2	2.3	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.2	2.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.2	1.9	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.2	2.6	GO:0000145	exocyst(GO:0000145)
0.1	2.9	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.1	1.7	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	15.6	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.1	0.5	GO:0035363	histone locus body(GO:0035363)
0.1	2.8	GO:0036020	endolysosome membrane(GO:0036020)
0.1	4.8	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.8	GO:0036157	outer dynein arm(GO:0036157)
0.1	3.4	GO:0005921	gap junction(GO:0005921)
0.1	13.8	GO:0005882	intermediate filament(GO:0005882)
0.1	0.5	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	5.6	GO:0005844	polysome(GO:0005844)
0.1	7.3	GO:0043195	terminal bouton(GO:0043195)
0.1	3.3	GO:0043034	costamere(GO:0043034)
0.1	1.3	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	1.0	GO:0043219	lateral loop(GO:0043219)
0.1	1.0	GO:0030478	actin cap(GO:0030478)
0.1	0.3	GO:0071920	cleavage body(GO:0071920)
0.1	0.5	GO:1990037	Lewy body core(GO:1990037)
0.1	1.4	GO:0031143	pseudopodium(GO:0031143)
0.1	0.9	GO:0008091	spectrin(GO:0008091)
0.1	0.5	GO:0005614	interstitial matrix(GO:0005614)
0.1	6.1	GO:0005901	caveola(GO:0005901)
0.0	1.0	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.4	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	5.7	GO:0001650	fibrillar center(GO:0001650)
0.0	0.6	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.9	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	2.7	GO:0072686	mitotic spindle(GO:0072686)
0.0	3.7	GO:0005875	microtubule associated complex(GO:0005875)
0.0	0.5	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	1.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	2.1	GO:0035580	specific granule lumen(GO:0035580)
0.0	3.3	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0	0.7	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.9	GO:0016592	mediator complex(GO:0016592)
0.0	0.6	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.8	GO:0008180	COP9 signalosome(GO:0008180)
0.0	1.9	GO:0016459	myosin complex(GO:0016459)
0.0	0.9	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	1.0	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.4	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	1.4	GO:0043202	lysosomal lumen(GO:0043202)
0.0	5.0	GO:0016607	nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.1	27.2	GO:0004556	alpha-amylase activity(GO:0004556)
5.7	28.7	GO:0004522	ribonuclease A activity(GO:0004522)
1.5	17.4	GO:0008430	selenium binding(GO:0008430)
1.1	6.8	GO:0004046	aminoacylase activity(GO:0004046)
1.0	6.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
1.0	6.9	GO:0005499	vitamin D binding(GO:0005499)
0.8	7.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7	6.6	GO:0016015	morphogen activity(GO:0016015)
0.7	2.9	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.7	9.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.7	3.5	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.7	4.6	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.6	19.2	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.6	4.8	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.6	3.5	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.6	2.9	GO:0050436	microfibril binding(GO:0050436)
0.6	6.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.4	1.3	GO:0031687	A2A adenosine receptor binding(GO:0031687)
0.4	2.0	GO:0005298	proline:sodium symporter activity(GO:0005298)
0.4	1.5	GO:0005148	prolactin receptor binding(GO:0005148)
0.4	2.2	GO:0015235	cobalamin transporter activity(GO:0015235)
0.4	3.5	GO:0004064	arylesterase activity(GO:0004064)
0.3	3.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3	7.7	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.3	1.1	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3	6.3	GO:0051429	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3	2.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.2	3.2	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	3.6	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.2	5.6	GO:0050780	dopamine receptor binding(GO:0050780)
0.2	2.7	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	1.3	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2	3.4	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.2	1.7	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.2	2.1	GO:0032027	myosin light chain binding(GO:0032027)
0.2	0.5	GO:0070052	collagen V binding(GO:0070052)
0.2	5.1	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.2	3.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	5.8	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.2	13.0	GO:0050840	extracellular matrix binding(GO:0050840)
0.2	3.0	GO:0097602	cullin family protein binding(GO:0097602)
0.2	2.6	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.2	4.3	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	3.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.4	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	1.7	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1	2.7	GO:0016595	glutamate binding(GO:0016595)
0.1	1.5	GO:0046625	sphingolipid binding(GO:0046625)
0.1	1.5	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.5	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1	0.7	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	7.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	3.8	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	1.8	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1	0.4	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.1	1.1	GO:0033038	bitter taste receptor activity(GO:0033038)
0.1	5.6	GO:0008146	sulfotransferase activity(GO:0008146)
0.1	0.8	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	4.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	1.9	GO:0008242	omega peptidase activity(GO:0008242)
0.1	0.9	GO:0042731	PH domain binding(GO:0042731)
0.1	0.5	GO:0017040	ceramidase activity(GO:0017040)
0.1	1.0	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	1.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	0.4	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.1	0.5	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	1.9	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	0.3	GO:0033677	DNA/RNA helicase activity(GO:0033677)
0.1	0.5	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	2.3	GO:0000146	microfilament motor activity(GO:0000146)
0.1	0.4	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	1.0	GO:0097016	L27 domain binding(GO:0097016)
0.1	1.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	1.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	6.6	GO:0005179	hormone activity(GO:0005179)
0.1	13.9	GO:0005516	calmodulin binding(GO:0005516)
0.1	1.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	5.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.8	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.4	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	2.3	GO:0004112	cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0	0.5	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	1.7	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	5.5	GO:0005178	integrin binding(GO:0005178)
0.0	0.6	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	2.7	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	4.9	GO:0008201	heparin binding(GO:0008201)
0.0	1.6	GO:0015485	cholesterol binding(GO:0015485)
0.0	3.9	GO:0008083	growth factor activity(GO:0008083)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.7	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	1.0	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.2	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	2.8	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	1.3	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.6	GO:0070628	proteasome binding(GO:0070628)
0.0	1.3	GO:0042805	actinin binding(GO:0042805)
0.0	1.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	1.9	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.1	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	1.3	GO:0017022	myosin binding(GO:0017022)
0.0	0.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.4	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.6	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.7	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.0	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	15.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.3	13.4	NABA COLLAGENS	Genes encoding collagen proteins
0.2	3.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	5.8	PID IGF1 PATHWAY	IGF1 pathway
0.1	7.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	6.6	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	2.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	3.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	3.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	4.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	5.8	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	3.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	1.0	PID ALK2 PATHWAY	ALK2 signaling events
0.1	2.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	1.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	1.8	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	2.8	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	1.8	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	1.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.7	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	3.5	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	2.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	1.1	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.0	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	5.0	NABA SECRETED FACTORS	Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.8	57.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.5	13.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	7.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	3.8	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	3.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	2.8	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	13.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	0.7	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.2	3.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.2	4.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	4.9	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	6.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	6.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	4.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	2.6	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	3.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	4.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	4.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.9	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	18.7	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.1	1.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	3.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	5.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	2.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	1.7	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.5	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	4.7	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	4.8	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	1.6	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	1.1	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	3.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.5	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	1.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	2.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.2	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	2.7	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins

Results for POU3F3_POU3F4

Z-value: 0.26

Motif logo

Transcription factors associated with POU3F3_POU3F4

Activity-expression correlation:

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: