avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
POU5F1 Links Ensembl NCBI GeneCards UniProt	ENSG00000204531.20	POU5F1
POU2F3 Links Ensembl NCBI GeneCards UniProt	ENSG00000137709.10	POU2F3

Gene	Promoter	Pearson corr. coef.	P-value	Plot
POU2F3	hg38_v1_chr11_+_120236635_120236642, hg38_v1_chr11_+_120240135_120240199	0.33	6.7e-07	Click!
POU5F1	hg38_v1_chr6_-_31170620_31170698	0.20	3.3e-03	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr2_-_89100352 Show fit	92.63	ENST00000479981.1	IGKV1-16 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-16
chr2_+_90100235 Show fit	90.54	ENST00000492446.1	IGKV1D-16 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-16
chr2_+_90021567 Show fit	86.69	ENST00000436451.2	IGKV6D-21 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6D-21 (non-functional)
chr2_+_90209873 Show fit	86.58	ENST00000468879.1	IGKV1D-43 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-43
chr2_-_88992903 Show fit	85.21	ENST00000495489.1	IGKV1-8 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-8
chr2_+_90159840 Show fit	83.58	ENST00000377032.5	IGKV1D-12 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-12
chr2_-_89160329 Show fit	80.22	ENST00000390256.2	IGKV6-21 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6-21 (non-functional)
chr14_-_106593319 Show fit	76.92	ENST00000390627.3	IGHV3-53 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-53
chr2_-_89040745 Show fit	76.61	ENST00000480492.1	IGKV1-12 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-12
chr2_+_90069662 Show fit	75.64	ENST00000390271.2	IGKV6D-41 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6D-41 (non-functional)
chr2_+_90038848 Show fit	73.85	ENST00000390270.2	IGKV3D-20 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-20
chr14_-_106117159 Show fit	70.62	ENST00000390601.3	IGHV3-11 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-11
chr2_+_90082635 Show fit	69.71	ENST00000483379.1	IGKV1D-17 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-17
chr22_+_22758698 Show fit	67.59	ENST00000390312.2	IGLV2-14 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-14
chr2_-_89245596 Show fit	66.02	ENST00000468494.1	IGKV2-30 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2-30
chr1_+_228458095 Show fit	64.52	ENST00000620438.1	H2BU1 Links Ensembl NCBI GeneCards UniProt Show fit	H2B.U histone 1
chr2_+_89936859 Show fit	63.94	ENST00000474213.1	IGKV2D-30 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-30
chr2_+_89959979 Show fit	61.58	ENST00000453166.2	IGKV2D-28 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-28
chr14_-_106675544 Show fit	60.19	ENST00000390632.2	IGHV3-66 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-66
chr22_+_22357739 Show fit	60.10	ENST00000390294.2	IGLV1-47 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-47
chr14_-_106277039 Show fit	59.69	ENST00000390610.2	IGHV1-24 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-24
chr22_+_22734577 Show fit	58.18	ENST00000390310.3	IGLV2-18 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-18
chr22_+_22431949 Show fit	55.85	ENST00000390301.3	IGLV1-36 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-36
chr14_-_106470788 Show fit	55.60	ENST00000434710.1	IGHV3-43 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-43
chr21_-_10649835 Show fit	53.19	ENST00000622028.1	IGHV1OR21-1 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr2_+_89851723 Show fit	52.21	ENST00000429992.2	IGKV2D-40 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-40
chr2_+_89884740 Show fit	51.93	ENST00000509129.1	IGKV1D-37 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-37 (non-functional)
chr2_-_89143133 Show fit	51.28	ENST00000492167.1	IGKV3-20 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-20
chr2_+_90114838 Show fit	50.78	ENST00000417279.3	IGKV3D-15 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-15
chr4_-_70666492 Show fit	49.25	ENST00000254801.9 ENST00000391614.7	JCHAIN Links Ensembl NCBI GeneCards UniProt Show fit	joining chain of multimeric IgA and IgM
chr2_+_89947508 Show fit	48.55	ENST00000491977.1	IGKV2D-29 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-29
chr2_+_89913982 Show fit	47.75	ENST00000390265.2	IGKV1D-33 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-33
chr14_-_106012390 Show fit	47.03	ENST00000455737.2	IGHV4-4 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-4
chr22_+_22720615 Show fit	46.80	ENST00000390309.2	IGLV3-19 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-19
chr2_-_89268506 Show fit	45.79	ENST00000473726.1	IGKV1-33 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-33
chr2_+_90154073 Show fit	45.60	ENST00000611391.1	IGKV1D-13 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-13
chr2_-_89320146 Show fit	45.44	ENST00000498574.1	IGKV1-39 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-39
chr15_-_21742799 Show fit	44.31	ENST00000622410.2	ENSG00000278263.2 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein, identical to IGHV4-4
chr14_-_106658251 Show fit	44.05	ENST00000454421.2	IGHV3-64 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64
chr2_-_89222461 Show fit	43.60	ENST00000482769.1	IGKV2-28 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2-28
chr22_+_22822658 Show fit	43.06	ENST00000620395.2	IGLV2-8 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-8
chr16_+_33802683 Show fit	43.04	ENST00000570121.2	IGHV3OR16-12 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr2_-_89297785 Show fit	42.70	ENST00000465170.1	IGKV1-37 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-37 (non-functional)
chrX_-_107775951 Show fit	42.47	ENST00000315660.8 ENST00000372384.6 ENST00000502650.1 ENST00000506724.1	TSC22D3 Links Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 3
chr16_+_23835946 Show fit	42.35	ENST00000321728.12 ENST00000643927.1	PRKCB Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C beta
chr14_-_106622837 Show fit	42.06	ENST00000390628.3	IGHV1-58 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-58
chr22_+_22792485 Show fit	41.43	ENST00000390314.2	IGLV2-11 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-11
chr14_-_106088573 Show fit	41.39	ENST00000632099.1	IGHV3-64D Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64D
chrX_-_107717054 Show fit	40.72	ENST00000503515.1 ENST00000372397.6	TSC22D3 Links Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 3
chr7_-_100586119 Show fit	40.71	ENST00000310300.11	LRCH4 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeats and calponin homology domain containing 4
chr14_-_106538331 Show fit	40.56	ENST00000390624.3	IGHV3-48 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-48
chr2_-_88947820 Show fit	40.36	ENST00000496168.1	IGKV1-5 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-5
chr16_+_32066065 Show fit	39.96	ENST00000354689.6	IGHV3OR16-9 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr14_-_106715166 Show fit	38.93	ENST00000390633.2	IGHV1-69 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69
chr11_-_5227063 Show fit	38.62	ENST00000335295.4 ENST00000485743.1 ENST00000647020.1	HBB Links Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit beta
chr22_+_22697789 Show fit	38.31	ENST00000390306.2	IGLV2-23 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-23
chr14_-_106762576 Show fit	37.69	ENST00000624687.1	IGHV1-69D Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69D
chr2_+_87338511 Show fit	36.77	ENST00000421835.2	IGKV3OR2-268 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr2_-_89213917 Show fit	36.64	ENST00000498435.1	IGKV1-27 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-27
chr2_-_88857582 Show fit	35.87	ENST00000390237.2	IGKC Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa constant
chr10_-_96271508 Show fit	35.61	ENST00000427367.6 ENST00000413476.6 ENST00000371176.6	BLNK Links Ensembl NCBI GeneCards UniProt Show fit	B cell linker
chr14_-_105987068 Show fit	35.53	ENST00000390594.3	IGHV1-2 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-2
chr15_-_19988117 Show fit	35.43	ENST00000558565.2	IGHV3OR15-7 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_+_89862438 Show fit	34.84	ENST00000448155.2	IGKV1D-39 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-39
chr2_-_88979016 Show fit	34.08	ENST00000390247.2	IGKV3-7 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_90234809 Show fit	34.04	ENST00000443397.5	IGKV3D-7 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-7
chr14_-_106389858 Show fit	33.97	ENST00000390617.2	IGHV3-35 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-35 (non-functional)
chr12_-_91180365 Show fit	33.54	ENST00000547937.5	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr6_-_32589833 Show fit	33.29	ENST00000360004.5	HLA-DRB1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DR beta 1
chr4_+_40192949 Show fit	32.84	ENST00000507851.5 ENST00000615577.4 ENST00000613272.4	RHOH Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member H
chr16_+_33009175 Show fit	32.69	ENST00000565407.2	IGHV3OR16-8 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr1_-_149886652 Show fit	32.52	ENST00000369155.3	H2BC21 Links Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 21
chr14_-_106025628 Show fit	32.32	ENST00000631943.1	IGHV7-4-1 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 7-4-1
chr2_+_88885397 Show fit	32.28	ENST00000390243.2	IGKV4-1 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 4-1
chr2_-_89117844 Show fit	32.07	ENST00000490686.1	IGKV1-17 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-17
chr22_+_22594528 Show fit	31.51	ENST00000390303.3	IGLV3-32 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-32 (non-functional)
chr2_+_113406368 Show fit	30.95	ENST00000453673.3	IGKV1OR2-108 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr3_+_186930759 Show fit	30.66	ENST00000677292.1 ENST00000458216.5	ST6GAL1 Links Ensembl NCBI GeneCards UniProt Show fit	ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr2_+_90172802 Show fit	30.34	ENST00000390277.3	IGKV3D-11 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-11
chr1_-_204411804 Show fit	29.20	ENST00000367188.5	PPP1R15B Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 15B
chr22_+_22747383 Show fit	29.15	ENST00000390311.3	IGLV3-16 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-16
chr12_-_91179355 Show fit	29.04	ENST00000550563.5 ENST00000546370.5	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr14_-_106154113 Show fit	28.85	ENST00000390603.2	IGHV3-15 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-15
chr2_-_88966767 Show fit	28.31	ENST00000464162.1	IGKV1-6 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-6
chr1_-_153390976 Show fit	28.15	ENST00000368732.5 ENST00000368733.4	S100A8 Links Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A8
chr2_-_89085787 Show fit	27.20	ENST00000390252.2	IGKV3-15 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-15
chr14_-_106374129 Show fit	27.14	ENST00000390616.2	IGHV4-34 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-34
chr6_+_37170133 Show fit	26.32	ENST00000373509.6	PIM1 Links Ensembl NCBI GeneCards UniProt Show fit	Pim-1 proto-oncogene, serine/threonine kinase
chr22_+_22686724 Show fit	26.07	ENST00000390305.2	IGLV3-25 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-25
chr6_-_107824294 Show fit	25.82	ENST00000369020.8 ENST00000369022.6	SCML4 Links Ensembl NCBI GeneCards UniProt Show fit	Scm polycomb group protein like 4
chr22_+_22409755 Show fit	25.81	ENST00000390299.2	IGLV1-40 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-40
chr17_-_49764123 Show fit	25.57	ENST00000240364.7 ENST00000506156.1	FAM117A Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 117 member A
chr6_-_32816910 Show fit	25.54	ENST00000447394.1 ENST00000438763.7	HLA-DOB Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DO beta
chr1_+_5992639 Show fit	25.37	ENST00000666163.1 ENST00000671676.1 ENST00000658883.1 ENST00000445501.6 ENST00000668706.1 ENST00000653262.1 ENST00000389632.9 ENST00000341524.6 ENST00000462676.3	KCNAB2 Links Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr3_+_186930518 Show fit	25.28	ENST00000169298.8 ENST00000457772.6 ENST00000455441.5 ENST00000427315.5	ST6GAL1 Links Ensembl NCBI GeneCards UniProt Show fit	ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr14_-_106627685 Show fit	25.04	ENST00000390629.3	IGHV4-59 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-59
chr19_+_19033575 Show fit	24.92	ENST00000392335.6 ENST00000537263.5 ENST00000540707.5 ENST00000535612.6 ENST00000541725.5 ENST00000269932.10 ENST00000546344.5 ENST00000540792.5 ENST00000536098.5 ENST00000541898.5	ARMC6 Links Ensembl NCBI GeneCards UniProt Show fit	armadillo repeat containing 6
chr19_+_21020675 Show fit	24.75	ENST00000595401.1	ZNF430 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 430
chr19_-_19033480 Show fit	24.30	ENST00000452918.7 ENST00000600377.1 ENST00000337018.10	SUGP2 Links Ensembl NCBI GeneCards UniProt Show fit	SURP and G-patch domain containing 2
chr18_-_55422492 Show fit	24.13	ENST00000561992.5 ENST00000630712.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr18_-_55401751 Show fit	24.05	ENST00000537856.7	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr18_-_55589795 Show fit	23.58	ENST00000568740.5 ENST00000629387.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr17_-_63932261 Show fit	23.53	ENST00000349817.2 ENST00000006750.8 ENST00000392795.7	CD79B Links Ensembl NCBI GeneCards UniProt Show fit	CD79b molecule
chr19_-_1021114 Show fit	23.37	ENST00000333175.9 ENST00000356663.8	TMEM259 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 259
chr18_-_55322215 Show fit	23.13	ENST00000457482.7	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr16_+_32995048 Show fit	23.11	ENST00000425181.3	IGHV3OR16-10 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr18_+_44680093 Show fit	22.83	ENST00000426838.8 ENST00000677068.1	SETBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SET binding protein 1
chr18_-_55588535 Show fit	22.76	ENST00000566286.5 ENST00000566279.5 ENST00000626595.2 ENST00000564999.5 ENST00000616053.4 ENST00000356073.8	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr18_-_55321986 Show fit	22.73	ENST00000570287.6	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr22_+_22818994 Show fit	22.54	ENST00000390316.2	IGLV3-9 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-9
chr8_-_133102477 Show fit	22.47	ENST00000522119.5 ENST00000523610.5 ENST00000338087.10 ENST00000521302.5 ENST00000519558.5 ENST00000519747.5 ENST00000517648.5	SLA Links Ensembl NCBI GeneCards UniProt Show fit	Src like adaptor
chr7_-_36985060 Show fit	22.46	ENST00000396040.6	ELMO1 Links Ensembl NCBI GeneCards UniProt Show fit	engulfment and cell motility 1
chr16_-_33845229 Show fit	22.07	ENST00000569103.2	IGHV3OR16-17 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr18_-_55589836 Show fit	21.86	ENST00000537578.5 ENST00000564403.6	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr18_-_55589770 Show fit	21.53	ENST00000565018.6 ENST00000636400.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr17_+_40062810 Show fit	21.40	ENST00000584985.5 ENST00000264637.8	THRA Links Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor alpha
chr22_+_22380766 Show fit	21.28	ENST00000390297.3	IGLV1-44 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-44
chr11_-_62601818 Show fit	21.27	ENST00000278823.7	MTA2 Links Ensembl NCBI GeneCards UniProt Show fit	metastasis associated 1 family member 2
chr17_+_7650916 Show fit	21.02	ENST00000250111.9	ATP1B2 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase Na+/K+ transporting subunit beta 2
chr5_-_172771187 Show fit	20.72	ENST00000239223.4	DUSP1 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 1
chr18_-_55321640 Show fit	20.16	ENST00000637169.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr22_-_23754376 Show fit	20.14	ENST00000398465.3 ENST00000248948.4	VPREB3 Links Ensembl NCBI GeneCards UniProt Show fit	V-set pre-B cell surrogate light chain 3
chr12_-_91182652 Show fit	20.07	ENST00000552145.5 ENST00000546745.5	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr19_-_38617912 Show fit	20.01	ENST00000591517.5	MAP4K1 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 1
chr15_-_19965101 Show fit	19.93	ENST00000338912.5	IGHV1OR15-9 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr22_+_22704265 Show fit	19.86	ENST00000390307.2	IGLV3-22 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-22
chr8_-_133102874 Show fit	19.75	ENST00000395352.7	SLA Links Ensembl NCBI GeneCards UniProt Show fit	Src like adaptor
chr19_+_52269579 Show fit	19.61	ENST00000593703.1 ENST00000439461.6 ENST00000601711.5 ENST00000599581.5	ZNF766 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 766
chr7_-_130440848 Show fit	19.51	ENST00000675803.1 ENST00000223208.10 ENST00000343969.10 ENST00000471201.6 ENST00000675649.1 ENST00000675168.1 ENST00000469826.2 ENST00000334451.6 ENST00000675962.1 ENST00000675563.1 ENST00000480206.2 ENST00000489512.5 ENST00000676243.1 ENST00000674539.1 ENST00000675935.1	CEP41 Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 41
chr12_-_7092422 Show fit	19.43	ENST00000543835.5 ENST00000647956.2 ENST00000535233.6	C1R Links Ensembl NCBI GeneCards UniProt Show fit	complement C1r
chr1_+_156150008 Show fit	19.31	ENST00000355014.6	SEMA4A Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 4A
chr2_-_89010515 Show fit	18.94	ENST00000493819.1	IGKV1-9 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chrX_-_13817027 Show fit	18.86	ENST00000493677.5 ENST00000355135.6 ENST00000316715.9	GPM6B Links Ensembl NCBI GeneCards UniProt Show fit	glycoprotein M6B
chr6_-_159000174 Show fit	18.86	ENST00000367069.7	RSPH3 Links Ensembl NCBI GeneCards UniProt Show fit	radial spoke head 3
chr18_-_55588184 Show fit	18.85	ENST00000354452.8 ENST00000565908.6 ENST00000635822.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr22_-_18936142 Show fit	18.74	ENST00000438924.5 ENST00000457083.1 ENST00000357068.11 ENST00000420436.5 ENST00000334029.6 ENST00000610940.4	PRODH Links Ensembl NCBI GeneCards UniProt Show fit	proline dehydrogenase 1
chr14_-_106811131 Show fit	18.65	ENST00000424969.2	IGHV3-74 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-74
chr14_-_106411021 Show fit	18.55	ENST00000390618.2	IGHV3-38 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-38 (non-functional)
chr18_+_44680875 Show fit	18.36	ENST00000649279.2 ENST00000677699.1	SETBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SET binding protein 1
chr20_+_35968566 Show fit	18.25	ENST00000373973.7 ENST00000349339.5 ENST00000489667.1 ENST00000538900.1	CNBD2 Links Ensembl NCBI GeneCards UniProt Show fit	cyclic nucleotide binding domain containing 2
chr14_-_106360320 Show fit	18.12	ENST00000390615.2	IGHV3-33 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-33
chr12_-_91182784 Show fit	18.07	ENST00000547568.6 ENST00000052754.10 ENST00000552962.5	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr16_+_90022600 Show fit	17.73	ENST00000620723.4 ENST00000268699.9	GAS8 Links Ensembl NCBI GeneCards UniProt Show fit	growth arrest specific 8
chr14_-_106165730 Show fit	17.68	ENST00000390604.2	IGHV3-16 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-16 (non-functional)
chr22_+_22811737 Show fit	17.53	ENST00000390315.3	IGLV3-10 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-10
chr17_-_75779758 Show fit	17.53	ENST00000592643.5 ENST00000591890.5 ENST00000587171.1 ENST00000254810.8 ENST00000589599.5	H3-3B Links Ensembl NCBI GeneCards UniProt Show fit	H3.3 histone B
chr1_-_30757767 Show fit	17.04	ENST00000294507.4	LAPTM5 Links Ensembl NCBI GeneCards UniProt Show fit	lysosomal protein transmembrane 5
chr7_+_100586304 Show fit	16.97	ENST00000241071.11	FBXO24 Links Ensembl NCBI GeneCards UniProt Show fit	F-box protein 24
chr14_-_106422175 Show fit	16.91	ENST00000390619.2	IGHV4-39 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-39
chr1_+_192809031 Show fit	16.63	ENST00000235382.7	RGS2 Links Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 2
chr12_+_25052634 Show fit	16.47	ENST00000548766.5	IRAG2 Links Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr19_-_38617928 Show fit	16.44	ENST00000396857.7 ENST00000586296.5	MAP4K1 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 1
chr12_+_25052512 Show fit	16.34	ENST00000557489.5 ENST00000354454.7 ENST00000536173.5	IRAG2 Links Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr18_+_44700796 Show fit	15.99	ENST00000677130.1	SETBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SET binding protein 1
chr14_-_106062670 Show fit	15.98	ENST00000390598.2	IGHV3-7 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-7
chr9_-_35618367 Show fit	15.95	ENST00000378431.5 ENST00000378430.3 ENST00000259633.9	CD72 Links Ensembl NCBI GeneCards UniProt Show fit	CD72 molecule
chr18_-_55351977 Show fit	15.93	ENST00000643689.1	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr12_-_6663136 Show fit	15.84	ENST00000396807.8 ENST00000619641.4 ENST00000446105.6	ING4 Links Ensembl NCBI GeneCards UniProt Show fit	inhibitor of growth family member 4
chr14_-_106639589 Show fit	15.80	ENST00000390630.3	IGHV4-61 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-61
chr19_-_52786742 Show fit	15.67	ENST00000338230.3 ENST00000648973.1	ZNF600 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 600
chr19_-_893172 Show fit	15.48	ENST00000325464.6 ENST00000312090.10	MED16 Links Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 16
chr22_+_39994926 Show fit	15.43	ENST00000333407.11	FAM83F Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 83 member F
chr13_-_76886397 Show fit	15.38	ENST00000377474.4	KCTD12 Links Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 12
chr13_-_99307387 Show fit	15.20	ENST00000376414.5	GPR183 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 183
chr12_-_16600703 Show fit	15.20	ENST00000616247.4	LMO3 Links Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr9_-_34691204 Show fit	15.16	ENST00000378800.3 ENST00000311925.7	CCL19 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 19
chr12_-_122716790 Show fit	15.12	ENST00000528880.3	HCAR3 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 3
chr12_-_16608073 Show fit	15.07	ENST00000441439.6	LMO3 Links Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr7_-_77199808 Show fit	15.03	ENST00000248598.6	FGL2 Links Ensembl NCBI GeneCards UniProt Show fit	fibrinogen like 2
chr12_+_25052732 Show fit	15.02	ENST00000547044.5	IRAG2 Links Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr8_+_55879818 Show fit	14.81	ENST00000520220.6 ENST00000519728.6	LYN Links Ensembl NCBI GeneCards UniProt Show fit	LYN proto-oncogene, Src family tyrosine kinase
chr12_-_91179517 Show fit	14.71	ENST00000551354.1	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr19_+_35329161 Show fit	14.51	ENST00000341773.10 ENST00000600131.5 ENST00000595780.5 ENST00000597916.5 ENST00000593867.5 ENST00000600424.5 ENST00000599811.5 ENST00000536635.6 ENST00000085219.10 ENST00000544992.6 ENST00000419549.6	CD22 Links Ensembl NCBI GeneCards UniProt Show fit	CD22 molecule
chr12_-_6663083 Show fit	14.50	ENST00000467678.5 ENST00000493873.1 ENST00000412586.6 ENST00000423703.6 ENST00000444704.5 ENST00000341550.9	ING4 Links Ensembl NCBI GeneCards UniProt Show fit	inhibitor of growth family member 4
chr15_-_22185402 Show fit	14.50	ENST00000557788.2	IGHV4OR15-8 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr8_+_19939246 Show fit	14.47	ENST00000650287.1	LPL Links Ensembl NCBI GeneCards UniProt Show fit	lipoprotein lipase
chr12_-_91179472 Show fit	14.44	ENST00000550099.5 ENST00000546391.5	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr11_-_64744102 Show fit	14.44	ENST00000431822.5 ENST00000394432.8 ENST00000377486.7	RASGRP2 Links Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 2
chr12_-_16608183 Show fit	14.24	ENST00000354662.5 ENST00000538051.5	LMO3 Links Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr6_-_152636855 Show fit	14.13	ENST00000367248.7 ENST00000423061.6	SYNE1 Links Ensembl NCBI GeneCards UniProt Show fit	spectrin repeat containing nuclear envelope protein 1
chr9_-_124771304 Show fit	13.91	ENST00000416460.6 ENST00000487099.7	NR6A1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 6 group A member 1
chrX_-_40647509 Show fit	13.51	ENST00000378421.1 ENST00000378426.5 ENST00000327877.10	CXorf38 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome X open reading frame 38
chr5_+_50665899 Show fit	13.50	ENST00000505697.6	PARP8 Links Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 8
chr2_-_50347789 Show fit	13.34	ENST00000628364.2	NRXN1 Links Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr1_+_103655760 Show fit	13.28	ENST00000370083.9	AMY1A Links Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 1A
chr1_+_92080305 Show fit	13.26	ENST00000342818.4 ENST00000636805.2	BTBD8 Links Ensembl NCBI GeneCards UniProt Show fit	BTB domain containing 8
chrX_-_13817346 Show fit	13.25	ENST00000356942.9	GPM6B Links Ensembl NCBI GeneCards UniProt Show fit	glycoprotein M6B
chr6_-_24877262 Show fit	13.09	ENST00000378023.8 ENST00000540914.5	RIPOR2 Links Ensembl NCBI GeneCards UniProt Show fit	RHO family interacting cell polarization regulator 2
chr10_-_96271553 Show fit	13.08	ENST00000224337.10	BLNK Links Ensembl NCBI GeneCards UniProt Show fit	B cell linker
chr1_+_32200587 Show fit	13.06	ENST00000373602.10 ENST00000421922.6 ENST00000681230.1	CCDC28B Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 28B
chr15_-_88256139 Show fit	13.05	ENST00000626019.2	NTRK3 Links Ensembl NCBI GeneCards UniProt Show fit	neurotrophic receptor tyrosine kinase 3
chr2_+_68365274 Show fit	13.01	ENST00000234313.8	PLEK Links Ensembl NCBI GeneCards UniProt Show fit	pleckstrin
chr18_-_55402187 Show fit	12.77	ENST00000630268.2 ENST00000570177.6	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr22_-_42614871 Show fit	12.69	ENST00000252115.10	POLDIP3 Links Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase delta interacting protein 3
chr19_+_53333731 Show fit	12.64	ENST00000595091.6 ENST00000458035.3	ZNF845 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 845
chr16_+_58249910 Show fit	12.55	ENST00000219299.8 ENST00000443128.6 ENST00000616795.1	CCDC113 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 113
chr12_-_11269696 Show fit	12.49	ENST00000381842.7	PRB3 Links Ensembl NCBI GeneCards UniProt Show fit	proline rich protein BstNI subfamily 3
chr1_-_100249815 Show fit	12.47	ENST00000370131.3 ENST00000681617.1 ENST00000681780.1 ENST00000370132.8	DBT Links Ensembl NCBI GeneCards UniProt Show fit	dihydrolipoamide branched chain transacylase E2
chr14_-_106557465 Show fit	12.42	ENST00000390625.3	IGHV3-49 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-49
chr6_-_137219340 Show fit	12.40	ENST00000367739.9 ENST00000458076.5 ENST00000414770.5	IFNGR1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 1

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.7	2615.3	GO:0006958	complement activation, classical pathway(GO:0006958)
12.9	38.6	GO:0030185	nitric oxide transport(GO:0030185)
11.4	57.2	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
10.9	32.7	GO:0052026	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
10.4	83.2	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
10.0	129.9	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
8.5	25.5	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
8.3	33.3	GO:0002399	MHC class II protein complex assembly(GO:0002399)
7.0	49.3	GO:0060267	positive regulation of respiratory burst(GO:0060267)
7.0	21.0	GO:1903288	positive regulation of potassium ion import(GO:1903288)
6.4	44.5	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
6.2	18.7	GO:0010133	proline catabolic process to glutamate(GO:0010133)
5.9	17.8	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
5.8	23.2	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
5.7	1007.7	GO:0002377	immunoglobulin production(GO:0002377)
5.3	21.1	GO:2000639	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
5.1	15.2	GO:0097026	dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
5.0	5.0	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
4.0	12.1	GO:0002305	gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
4.0	16.0	GO:0099558	maintenance of synapse structure(GO:0099558)
3.9	7.9	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
3.9	11.7	GO:0060086	circadian temperature homeostasis(GO:0060086)
3.6	10.9	GO:0071226	response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226)
3.6	18.0	GO:0014807	regulation of somitogenesis(GO:0014807)
3.4	17.1	GO:0045925	positive regulation of female receptivity(GO:0045925)
3.3	16.6	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
3.3	10.0	GO:0099557	trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
3.3	19.7	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
3.2	29.2	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
3.2	12.8	GO:0036269	swimming behavior(GO:0036269)
3.2	25.4	GO:0070995	NADPH oxidation(GO:0070995)
3.1	27.6	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
3.0	36.5	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
3.0	33.0	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
3.0	20.9	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
3.0	8.9	GO:0021593	rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
2.9	8.6	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)
2.8	28.2	GO:0032119	sequestering of zinc ion(GO:0032119)
2.8	19.5	GO:0018095	protein polyglutamylation(GO:0018095)
2.8	8.3	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
2.8	11.0	GO:0003431	growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431)
2.7	8.0	GO:0072709	cellular response to sorbitol(GO:0072709)
2.6	18.5	GO:1904526	regulation of microtubule binding(GO:1904526)
2.6	13.1	GO:0044027	hypermethylation of CpG island(GO:0044027)
2.6	13.1	GO:2001107	negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
2.5	20.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
2.5	4.9	GO:0090264	immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
2.5	44.3	GO:0045199	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
2.4	17.0	GO:0033029	neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
2.3	42.1	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
2.3	30.3	GO:0043983	histone H4-K12 acetylation(GO:0043983)
2.3	18.6	GO:0003190	atrioventricular valve formation(GO:0003190)
2.3	11.3	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.2	26.3	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
2.2	6.6	GO:0019075	virus maturation(GO:0019075)
2.2	13.0	GO:0033625	positive regulation of integrin activation(GO:0033625)
2.2	8.7	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
2.2	6.5	GO:0061026	cardiac muscle tissue regeneration(GO:0061026)
2.1	14.8	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
2.1	6.3	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
2.1	4.1	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
2.0	18.1	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
2.0	20.0	GO:0006957	complement activation, alternative pathway(GO:0006957)
2.0	11.9	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.0	7.8	GO:1900158	positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.9	15.2	GO:0043615	astrocyte cell migration(GO:0043615)
1.9	5.7	GO:0060366	subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
1.9	7.5	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
1.8	7.3	GO:0043375	negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
1.8	9.1	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
1.8	7.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
1.7	3.5	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
1.7	13.7	GO:0019732	antifungal humoral response(GO:0019732)
1.7	5.0	GO:0071934	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.7	8.3	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
1.6	4.9	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
1.6	8.2	GO:0038161	prolactin signaling pathway(GO:0038161)
1.6	14.6	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.6	12.9	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
1.6	6.3	GO:0000023	maltose metabolic process(GO:0000023)
1.5	7.7	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
1.5	4.6	GO:0051946	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
1.5	7.6	GO:0030070	insulin processing(GO:0030070)
1.5	4.6	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621) hepatic duct development(GO:0061011)
1.5	4.5	GO:0097535	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
1.5	10.5	GO:0043696	forebrain anterior/posterior pattern specification(GO:0021797) dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
1.5	7.4	GO:0008050	courtship behavior(GO:0007619) female courtship behavior(GO:0008050)
1.4	1.4	GO:0032752	positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
1.4	9.9	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
1.4	4.2	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
1.4	20.7	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.3	8.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
1.3	4.0	GO:0060661	submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
1.3	1.3	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.3	9.2	GO:0001714	endodermal cell fate specification(GO:0001714)
1.3	9.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
1.3	3.8	GO:0097473	response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
1.3	5.1	GO:0030035	microspike assembly(GO:0030035)
1.3	3.8	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
1.3	6.3	GO:0033058	directional locomotion(GO:0033058)
1.2	4.9	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
1.2	6.0	GO:0002606	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
1.2	7.2	GO:0061737	leukotriene signaling pathway(GO:0061737)
1.2	22.6	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
1.2	4.7	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
1.1	9.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.1	13.3	GO:0048251	elastic fiber assembly(GO:0048251)
1.1	7.6	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
1.1	2.2	GO:0048852	hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
1.1	8.5	GO:0070842	aggresome assembly(GO:0070842)
1.0	7.3	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.0	25.6	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
1.0	9.1	GO:0033088	regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.0	5.0	GO:0007412	axon target recognition(GO:0007412)
1.0	4.0	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
1.0	3.0	GO:1903028	regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
1.0	23.8	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
1.0	2.9	GO:0061386	closure of optic fissure(GO:0061386)
1.0	5.8	GO:0006196	AMP catabolic process(GO:0006196)
1.0	4.8	GO:1903244	positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.0	8.7	GO:0030822	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822)
1.0	6.7	GO:0090324	negative regulation of oxidative phosphorylation(GO:0090324)
0.9	7.5	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.9	2.8	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.9	4.6	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.9	9.1	GO:0001865	NK T cell differentiation(GO:0001865)
0.9	37.2	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.9	3.6	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.9	4.5	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.9	2.7	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.9	2.7	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.9	8.9	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.9	2.7	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.9	3.4	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.9	17.9	GO:0044146	negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.8	3.4	GO:0046485	ether lipid metabolic process(GO:0046485)
0.8	4.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.8	11.7	GO:0048665	neuron fate specification(GO:0048665)
0.8	12.2	GO:0006600	creatine metabolic process(GO:0006600)
0.8	5.7	GO:0034587	piRNA metabolic process(GO:0034587)
0.8	13.0	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.8	8.8	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.8	3.2	GO:0019477	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.8	21.6	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.8	4.6	GO:0060594	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) mammary gland specification(GO:0060594) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915) regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.8	4.6	GO:0021648	thorax and anterior abdomen determination(GO:0007356) vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
0.7	4.5	GO:0006689	ganglioside catabolic process(GO:0006689)
0.7	2.2	GO:0048733	sebaceous gland development(GO:0048733)
0.7	4.4	GO:0030223	neutrophil differentiation(GO:0030223)
0.7	7.1	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.7	0.7	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.7	2.8	GO:0072396	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.7	2.8	GO:1990502	dense core granule maturation(GO:1990502)
0.7	2.8	GO:2000196	positive regulation of female gonad development(GO:2000196)
0.7	2.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.7	2.1	GO:0061590	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.7	9.1	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.7	26.0	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.7	188.3	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.7	10.9	GO:0031033	myosin filament organization(GO:0031033)
0.7	2.7	GO:0021759	globus pallidus development(GO:0021759)
0.7	8.8	GO:1990440	ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.7	6.8	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.7	5.3	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.7	11.9	GO:0015671	oxygen transport(GO:0015671)
0.7	7.9	GO:0042908	xenobiotic transport(GO:0042908)
0.7	7.8	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.7	3.9	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.6	71.3	GO:0030183	B cell differentiation(GO:0030183)
0.6	42.0	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.6	5.2	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.6	8.4	GO:2000811	negative regulation of anoikis(GO:2000811)
0.6	16.6	GO:0050832	defense response to fungus(GO:0050832)
0.6	8.2	GO:0010991	regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.6	5.7	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.6	9.4	GO:0048263	determination of dorsal identity(GO:0048263)
0.6	3.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.6	6.1	GO:0006824	cobalt ion transport(GO:0006824)
0.6	1.2	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.6	3.0	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.6	1.8	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.6	7.2	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.6	5.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.6	4.1	GO:0036343	psychomotor behavior(GO:0036343)
0.6	2.9	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.6	2.2	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.6	2.8	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.6	5.5	GO:0072672	neutrophil extravasation(GO:0072672)
0.5	2.2	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.5	1.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.5	29.3	GO:0021762	substantia nigra development(GO:0021762)
0.5	12.4	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.5	15.9	GO:0016601	Rac protein signal transduction(GO:0016601)
0.5	7.9	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.5	4.2	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.5	8.1	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.5	5.5	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.5	5.8	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.5	21.9	GO:0010762	regulation of fibroblast migration(GO:0010762)
0.5	2.4	GO:0090131	mesenchyme migration(GO:0090131)
0.5	28.3	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.5	5.1	GO:0008343	adult feeding behavior(GO:0008343)
0.5	2.8	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.5	4.6	GO:0086028	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.5	2.3	GO:2000291	regulation of myoblast proliferation(GO:2000291)
0.5	12.3	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.5	10.5	GO:0021542	dentate gyrus development(GO:0021542)
0.5	5.4	GO:0030322	stabilization of membrane potential(GO:0030322)
0.5	8.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.4	0.9	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4	6.2	GO:1990001	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.4	8.3	GO:0036035	osteoclast development(GO:0036035)
0.4	8.8	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.4	10.0	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.4	1.7	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.4	1.3	GO:0098758	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.4	1.3	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.4	7.6	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.4	1.3	GO:0001983	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.4	1.6	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.4	2.4	GO:0046092	deoxycytidine metabolic process(GO:0046092)
0.4	29.9	GO:0071277	cellular response to calcium ion(GO:0071277)
0.4	11.4	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4	9.0	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.4	1.6	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.4	12.5	GO:0009081	branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.4	5.0	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4	3.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.4	8.4	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.4	6.8	GO:0005513	detection of calcium ion(GO:0005513)
0.4	3.7	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.4	3.7	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.4	2.5	GO:0042756	drinking behavior(GO:0042756)
0.4	1.1	GO:0042560	folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.3	7.3	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.3	2.4	GO:0046886	positive regulation of hormone biosynthetic process(GO:0046886)
0.3	4.0	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.3	4.6	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.3	2.6	GO:0006572	tyrosine catabolic process(GO:0006572)
0.3	2.3	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.3	9.7	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.3	75.8	GO:0002250	adaptive immune response(GO:0002250)
0.3	1.2	GO:0034773	histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.3	2.4	GO:0070166	enamel mineralization(GO:0070166)
0.3	2.1	GO:0060452	positive regulation of cardiac muscle contraction(GO:0060452)
0.3	2.9	GO:0097369	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3	0.8	GO:0003139	secondary heart field specification(GO:0003139)
0.3	1.7	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3	20.1	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.3	2.4	GO:0060074	synapse maturation(GO:0060074)
0.3	4.3	GO:0001709	cell fate determination(GO:0001709)
0.3	3.5	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.3	2.6	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.3	2.6	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.3	1.8	GO:0044557	relaxation of smooth muscle(GO:0044557)
0.3	3.1	GO:1904903	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.3	6.0	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.3	4.4	GO:0021854	hypothalamus development(GO:0021854)
0.3	3.0	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.2	1.2	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.2	4.7	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.2	3.5	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.2	24.9	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2	5.9	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.2	7.3	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.2	6.3	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.2	8.7	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.2	1.2	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2	3.5	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	3.1	GO:0036158	outer dynein arm assembly(GO:0036158)
0.2	1.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2	2.4	GO:2000821	regulation of grooming behavior(GO:2000821)
0.2	9.0	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.2	4.9	GO:0046135	pyrimidine nucleoside catabolic process(GO:0046135)
0.2	1.9	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2	2.1	GO:0015870	acetylcholine transport(GO:0015870)
0.2	9.9	GO:0016239	positive regulation of macroautophagy(GO:0016239)
0.2	6.8	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2	4.4	GO:0046069	cGMP catabolic process(GO:0046069)
0.2	1.0	GO:0048539	bone marrow development(GO:0048539)
0.2	1.9	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.2	6.4	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2	1.3	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2	4.2	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2	0.6	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2	5.1	GO:0033198	response to ATP(GO:0033198)
0.2	4.7	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.2	3.6	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2	2.9	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.2	3.2	GO:0006590	thyroid hormone generation(GO:0006590)
0.2	11.9	GO:0048278	vesicle docking(GO:0048278)
0.2	5.5	GO:0006376	mRNA splice site selection(GO:0006376)
0.2	3.4	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.2	4.8	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2	0.3	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.2	5.4	GO:0010107	potassium ion import(GO:0010107)
0.1	1.7	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.1	0.3	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1	4.4	GO:0060976	coronary vasculature development(GO:0060976)
0.1	3.5	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.1	3.2	GO:0007608	sensory perception of smell(GO:0007608)
0.1	3.7	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.1	16.2	GO:0048839	inner ear development(GO:0048839)
0.1	2.3	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	6.9	GO:0006968	cellular defense response(GO:0006968)
0.1	5.9	GO:0019730	antimicrobial humoral response(GO:0019730)
0.1	0.7	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	2.9	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.1	4.9	GO:0019228	neuronal action potential(GO:0019228)
0.1	7.3	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.1	1.9	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.1	0.4	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.1	0.2	GO:0021514	ventral spinal cord interneuron differentiation(GO:0021514)
0.1	3.9	GO:0016486	peptide hormone processing(GO:0016486)
0.1	2.0	GO:0035640	exploration behavior(GO:0035640)
0.1	2.6	GO:0042417	dopamine metabolic process(GO:0042417)
0.1	1.2	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.1	0.9	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.1	0.8	GO:0002507	tolerance induction(GO:0002507)
0.1	0.7	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	2.2	GO:0006706	steroid catabolic process(GO:0006706)
0.1	0.7	GO:0003360	brainstem development(GO:0003360)
0.1	0.7	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	0.2	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1	4.7	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	1.5	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	0.4	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.1	0.7	GO:0043507	positive regulation of JUN kinase activity(GO:0043507)
0.1	0.5	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.1	3.2	GO:0007631	feeding behavior(GO:0007631)
0.1	1.0	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.1	1.5	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	2.2	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0	2.2	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.0	1.3	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	3.3	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0	0.4	GO:0038084	vascular endothelial growth factor signaling pathway(GO:0038084)
0.0	0.9	GO:0003091	renal water homeostasis(GO:0003091)
0.0	1.7	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.5	GO:0060711	labyrinthine layer development(GO:0060711)
0.0	0.5	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.5	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	1.4	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	0.1	GO:0006116	NADH oxidation(GO:0006116)
0.0	1.3	GO:0070268	cornification(GO:0070268)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
33.5	100.5	GO:0071754	IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
15.1	756.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
10.0	129.9	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
9.7	38.6	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
7.4	22.1	GO:0098843	postsynaptic endocytic zone(GO:0098843)
6.9	34.5	GO:0019815	B cell receptor complex(GO:0019815)
5.1	25.4	GO:1990031	pinceau fiber(GO:1990031)
3.4	610.5	GO:0072562	blood microparticle(GO:0072562)
3.1	58.8	GO:0042613	MHC class II protein complex(GO:0042613)
3.0	21.1	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
3.0	14.8	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
2.7	13.6	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
2.7	8.0	GO:0030485	smooth muscle contractile fiber(GO:0030485)
2.5	15.0	GO:0005577	fibrinogen complex(GO:0005577)
2.5	12.5	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
2.4	12.0	GO:0044308	axonal spine(GO:0044308)
2.2	8.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
1.9	20.5	GO:0005955	calcineurin complex(GO:0005955)
1.8	14.6	GO:0035976	AP1 complex(GO:0035976)
1.7	29.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
1.7	13.3	GO:0071953	elastic fiber(GO:0071953)
1.7	18.2	GO:0060171	stereocilium membrane(GO:0060171)
1.6	22.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
1.6	4.7	GO:0032437	cuticular plate(GO:0032437)
1.5	9.1	GO:0045298	tubulin complex(GO:0045298)
1.4	5.7	GO:0071546	pi-body(GO:0071546)
1.4	4.2	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.3	33.1	GO:0044295	axonal growth cone(GO:0044295)
1.3	10.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
1.3	22.6	GO:0000346	transcription export complex(GO:0000346)
1.2	21.0	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
1.1	3.2	GO:0031933	telomeric heterochromatin(GO:0031933)
1.0	7.3	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
1.0	4.0	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
1.0	196.2	GO:0032993	protein-DNA complex(GO:0032993)
0.9	2.8	GO:0043293	apoptosome(GO:0043293)
0.9	11.2	GO:0005687	U4 snRNP(GO:0005687)
0.9	2.8	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.9	2.7	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.9	36.0	GO:0016592	mediator complex(GO:0016592)
0.9	2.7	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.9	17.1	GO:0042627	chylomicron(GO:0042627)
0.8	8.4	GO:0043596	nuclear replication fork(GO:0043596)
0.8	8.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.8	1319.1	GO:0005615	extracellular space(GO:0005615)
0.7	6.6	GO:0000813	ESCRT I complex(GO:0000813)
0.7	3.6	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.7	17.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.7	6.8	GO:0031083	BLOC-1 complex(GO:0031083)
0.7	4.0	GO:0000322	storage vacuole(GO:0000322)
0.7	60.6	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.7	8.7	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.6	19.4	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.6	40.9	GO:0001772	immunological synapse(GO:0001772)
0.6	25.5	GO:0001533	cornified envelope(GO:0001533)
0.6	4.8	GO:0005833	hemoglobin complex(GO:0005833)
0.6	9.5	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.6	11.6	GO:0005657	replication fork(GO:0005657)
0.6	74.0	GO:0016605	PML body(GO:0016605)
0.6	70.3	GO:0042734	presynaptic membrane(GO:0042734)
0.6	33.7	GO:0030426	growth cone(GO:0030426)
0.5	5.9	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.5	4.5	GO:0043083	synaptic cleft(GO:0043083)
0.4	3.1	GO:0036157	outer dynein arm(GO:0036157)
0.4	27.4	GO:0031901	early endosome membrane(GO:0031901)
0.4	5.0	GO:0016013	syntrophin complex(GO:0016013)
0.4	2.4	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.4	12.7	GO:0030027	lamellipodium(GO:0030027)
0.4	12.6	GO:0034451	centriolar satellite(GO:0034451)
0.3	8.5	GO:0016235	aggresome(GO:0016235)
0.3	5.1	GO:0031594	neuromuscular junction(GO:0031594)
0.3	2.3	GO:1990037	Lewy body core(GO:1990037)
0.3	9.0	GO:0043204	perikaryon(GO:0043204)
0.3	13.2	GO:0031430	M band(GO:0031430)
0.3	9.2	GO:0031904	endosome lumen(GO:0031904)
0.3	3.7	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3	1.4	GO:0002080	acrosomal membrane(GO:0002080)
0.3	5.2	GO:0046930	pore complex(GO:0046930)
0.3	7.9	GO:0005859	muscle myosin complex(GO:0005859)
0.3	2.4	GO:0098839	postsynaptic density membrane(GO:0098839)
0.3	17.7	GO:0043195	terminal bouton(GO:0043195)
0.3	8.1	GO:0000791	euchromatin(GO:0000791)
0.2	3.1	GO:0000815	ESCRT III complex(GO:0000815)
0.2	6.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.2	9.7	GO:1904115	axon cytoplasm(GO:1904115)
0.2	19.3	GO:0036064	ciliary basal body(GO:0036064)
0.2	20.4	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.2	4.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2	1.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	5.3	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.2	1.9	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2	2.3	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.2	5.8	GO:0044309	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.2	26.3	GO:0032587	ruffle membrane(GO:0032587)
0.2	6.4	GO:0014704	intercalated disc(GO:0014704)
0.2	2.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	8.8	GO:0016459	myosin complex(GO:0016459)
0.2	2.4	GO:0048786	presynaptic active zone(GO:0048786)
0.2	8.7	GO:0005902	microvillus(GO:0005902)
0.2	11.8	GO:0001726	ruffle(GO:0001726)
0.1	4.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	1.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.1	4.0	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	2.7	GO:0031932	TORC2 complex(GO:0031932)
0.1	2.9	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1	636.6	GO:0005886	plasma membrane(GO:0005886)
0.1	2.9	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	16.8	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	1.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.1	2.7	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	5.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	10.6	GO:0001650	fibrillar center(GO:0001650)
0.1	1.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.8	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	1.2	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.7	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	2.2	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	2.5	GO:0045202	synapse(GO:0045202)
0.0	1.0	GO:0016363	nuclear matrix(GO:0016363)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.4	3656.9	GO:0003823	antigen binding(GO:0003823)
12.5	261.8	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
11.2	55.9	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
10.6	42.4	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
9.4	28.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
8.4	75.7	GO:0043426	MRF binding(GO:0043426)
6.9	20.7	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
6.2	43.7	GO:0030492	hemoglobin binding(GO:0030492)
4.8	14.5	GO:0017129	triglyceride binding(GO:0017129)
4.4	13.3	GO:0004556	alpha-amylase activity(GO:0004556)
4.4	21.8	GO:0010861	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
4.3	34.1	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
3.5	10.6	GO:0004157	dihydropyrimidinase activity(GO:0004157)
3.1	12.4	GO:0004906	interferon-gamma receptor activity(GO:0004906)
3.0	11.9	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
3.0	32.7	GO:0005030	neurotrophin receptor activity(GO:0005030)
2.9	8.7	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
2.9	8.6	GO:0030226	apolipoprotein receptor activity(GO:0030226)
2.9	48.7	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.8	8.3	GO:0008859	exoribonuclease II activity(GO:0008859)
2.7	13.7	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
2.7	8.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
2.5	15.2	GO:0008142	oxysterol binding(GO:0008142)
2.5	15.2	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
2.5	14.8	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
2.5	12.3	GO:0043208	glycosphingolipid binding(GO:0043208)
2.4	9.8	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.4	11.8	GO:0004522	ribonuclease A activity(GO:0004522)
2.3	9.2	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
2.3	9.1	GO:0099609	microtubule lateral binding(GO:0099609)
2.1	6.3	GO:0030158	protein xylosyltransferase activity(GO:0030158)
2.1	8.2	GO:0004925	prolactin receptor activity(GO:0004925)
2.0	4.0	GO:0080084	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
1.9	13.4	GO:0046625	sphingolipid binding(GO:0046625)
1.9	7.5	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
1.8	36.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
1.8	16.2	GO:0050682	AF-2 domain binding(GO:0050682)
1.8	21.0	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
1.7	13.8	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.7	8.6	GO:0030109	HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
1.7	6.8	GO:0004668	protein-arginine deiminase activity(GO:0004668)
1.7	20.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
1.7	5.0	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.6	3.3	GO:0042806	fucose binding(GO:0042806)
1.6	4.9	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
1.6	26.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
1.6	45.5	GO:0097109	neuroligin family protein binding(GO:0097109)
1.6	6.3	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
1.6	7.9	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.5	20.1	GO:0070324	thyroid hormone binding(GO:0070324)
1.5	4.6	GO:1990430	extracellular matrix protein binding(GO:1990430)
1.5	38.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
1.5	9.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
1.5	4.5	GO:0042008	interleukin-18 receptor activity(GO:0042008)
1.5	4.5	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
1.5	4.5	GO:0052795	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.5	14.7	GO:0005549	odorant binding(GO:0005549)
1.4	5.7	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
1.4	2.8	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
1.4	116.8	GO:0050840	extracellular matrix binding(GO:0050840)
1.3	4.0	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
1.3	4.0	GO:0032427	GBD domain binding(GO:0032427)
1.3	19.7	GO:0042809	vitamin D receptor binding(GO:0042809)
1.3	13.8	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
1.2	17.3	GO:0035325	Toll-like receptor binding(GO:0035325)
1.2	4.9	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
1.2	3.6	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
1.2	12.7	GO:0051525	NFAT protein binding(GO:0051525)
1.1	26.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.1	7.7	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.1	22.4	GO:0019992	diacylglycerol binding(GO:0019992)
1.0	6.0	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
1.0	6.0	GO:0016807	cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
1.0	11.9	GO:0005344	oxygen transporter activity(GO:0005344)
1.0	4.9	GO:0070097	delta-catenin binding(GO:0070097)
0.9	3.7	GO:0047291	neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.9	3.7	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.9	3.6	GO:0047708	biotinidase activity(GO:0047708)
0.9	2.7	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.9	11.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.9	3.4	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.9	12.8	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.8	5.9	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.8	5.1	GO:0003998	acylphosphatase activity(GO:0003998)
0.8	5.0	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.8	10.0	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.8	11.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.8	4.9	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.8	2.4	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.8	8.7	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.8	11.7	GO:0001222	transcription corepressor binding(GO:0001222)
0.8	2.3	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.7	4.3	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.7	11.5	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) retinal binding(GO:0016918)
0.7	7.9	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.7	5.0	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.7	4.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.7	22.7	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.7	11.9	GO:0008179	adenylate cyclase binding(GO:0008179)
0.7	13.2	GO:0005112	Notch binding(GO:0005112)
0.7	21.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.6	5.8	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6	1.9	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6	3.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.6	3.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.6	3.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.6	6.3	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.6	18.1	GO:0071949	FAD binding(GO:0071949)
0.6	2.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.6	7.3	GO:0051434	BH3 domain binding(GO:0051434)
0.5	2.2	GO:0004031	aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.5	6.5	GO:0022842	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.5	2.2	GO:0004773	steryl-sulfatase activity(GO:0004773)
0.5	2.1	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.5	1.5	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.5	17.5	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.5	3.0	GO:0003796	lysozyme activity(GO:0003796)
0.5	4.5	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.5	6.0	GO:0042834	peptidoglycan binding(GO:0042834)
0.5	5.5	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.5	16.5	GO:0001671	ATPase activator activity(GO:0001671)
0.5	6.5	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.5	24.2	GO:0030552	cAMP binding(GO:0030552)
0.5	3.4	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.5	9.6	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.5	10.0	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.4	7.5	GO:0048018	receptor agonist activity(GO:0048018)
0.4	36.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.4	9.9	GO:0070403	NAD+ binding(GO:0070403)
0.4	1.3	GO:0019959	interleukin-8 binding(GO:0019959)
0.4	5.6	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.4	4.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.4	4.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.4	4.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.4	7.9	GO:0050786	RAGE receptor binding(GO:0050786)
0.4	8.2	GO:0030553	cGMP binding(GO:0030553)
0.4	12.2	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.4	3.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.4	4.6	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.4	2.7	GO:0008172	S-methyltransferase activity(GO:0008172)
0.4	2.3	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.4	7.0	GO:0038191	neuropilin binding(GO:0038191)
0.4	2.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.4	1.1	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.3	10.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.3	64.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3	2.4	GO:0004137	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.3	3.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3	7.4	GO:0002162	dystroglycan binding(GO:0002162)
0.3	3.4	GO:0004064	arylesterase activity(GO:0004064)
0.3	1.3	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3	5.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3	1.3	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.3	8.5	GO:0005109	frizzled binding(GO:0005109)
0.3	1.3	GO:0031716	calcitonin receptor binding(GO:0031716)
0.3	5.0	GO:0015250	water channel activity(GO:0015250)
0.3	1.2	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.3	0.3	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.3	7.5	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.3	5.7	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.3	4.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.3	5.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.3	1.4	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.3	2.9	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3	9.9	GO:0071889	14-3-3 protein binding(GO:0071889)
0.3	11.3	GO:0050699	WW domain binding(GO:0050699)
0.3	2.7	GO:0031386	protein tag(GO:0031386)
0.3	3.5	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3	7.8	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.3	7.7	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.3	9.2	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.3	3.8	GO:0031432	titin binding(GO:0031432)
0.3	12.3	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3	31.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	12.5	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2	4.7	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.2	2.7	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.2	3.5	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2	4.7	GO:0050811	GABA receptor binding(GO:0050811)
0.2	8.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.2	4.2	GO:0001055	RNA polymerase II activity(GO:0001055)
0.2	5.5	GO:0035198	miRNA binding(GO:0035198)
0.2	1.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.2	4.4	GO:0099589	serotonin receptor activity(GO:0099589)
0.2	4.0	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2	19.8	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2	2.9	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.2	1.0	GO:0004771	sterol esterase activity(GO:0004771)
0.2	3.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.2	4.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.2	0.8	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.2	5.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	2.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.2	7.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.2	6.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2	4.3	GO:0042166	acetylcholine binding(GO:0042166)
0.2	3.9	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.2	4.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2	19.1	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2	30.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	3.7	GO:0005521	lamin binding(GO:0005521)
0.2	1.7	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1	6.8	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	3.6	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	5.6	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	2.4	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	6.7	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	4.8	GO:0004890	GABA-A receptor activity(GO:0004890)
0.1	2.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	31.5	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.1	3.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	2.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1	4.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	4.0	GO:0030332	cyclin binding(GO:0030332)
0.1	4.0	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	0.7	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.1	0.7	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	1.4	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.1	1.5	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	0.3	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1	8.6	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.1	0.4	GO:0003883	CTP synthase activity(GO:0003883)
0.1	1.7	GO:0005522	profilin binding(GO:0005522)
0.1	0.5	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	11.2	GO:0031072	heat shock protein binding(GO:0031072)
0.1	3.4	GO:0008009	chemokine activity(GO:0008009)
0.1	4.1	GO:0032934	cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.1	3.6	GO:0022834	ligand-gated ion channel activity(GO:0015276) ligand-gated channel activity(GO:0022834)
0.1	1.8	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	1.3	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1	0.4	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	5.8	GO:0004984	olfactory receptor activity(GO:0004984)
0.1	11.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	0.7	GO:0031404	chloride ion binding(GO:0031404)
0.1	6.7	GO:0019208	phosphatase regulator activity(GO:0019208)
0.1	1.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	1.1	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	2.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	0.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	1.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.8	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.0	0.1	GO:0061609	fructose-1-phosphate aldolase activity(GO:0061609)
0.0	0.6	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	1.3	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	1.5	GO:0051117	ATPase binding(GO:0051117)
0.0	0.4	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	1.3	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.6	83.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
2.3	116.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
1.7	271.1	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
1.5	61.9	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
1.4	20.2	ST G ALPHA S PATHWAY	G alpha s Pathway
1.4	21.3	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
1.3	26.3	PID IL5 PATHWAY	IL5-mediated signaling events
1.0	31.0	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.9	49.8	PID BCR 5PATHWAY	BCR signaling pathway
0.9	17.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.8	15.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.8	7.2	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.8	34.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.8	60.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.7	8.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.7	21.9	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.6	6.4	PID RAS PATHWAY	Regulation of Ras family activation
0.6	13.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.6	21.1	PID MYC PATHWAY	C-MYC pathway
0.6	21.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.6	21.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.5	17.6	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.5	7.1	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.5	17.7	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.5	63.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.5	26.6	PID MTOR 4PATHWAY	mTOR signaling pathway
0.5	10.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.4	10.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.4	9.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.4	15.0	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.4	2.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.4	7.8	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.3	7.8	PID TRAIL PATHWAY	TRAIL signaling pathway
0.3	4.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.3	4.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.3	5.8	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3	13.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.3	18.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.3	8.0	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.3	13.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.2	4.8	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	5.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	5.6	PID ENDOTHELIN PATHWAY	Endothelins
0.2	8.5	PID ARF6 PATHWAY	Arf6 signaling events
0.2	7.2	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.2	8.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.2	10.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.2	3.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	1.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.2	5.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.2	3.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	2.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	5.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	4.0	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	4.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	5.2	PID SHP2 PATHWAY	SHP2 signaling
0.1	4.0	PID FGF PATHWAY	FGF signaling pathway
0.1	2.8	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	26.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	12.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	1.8	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	2.8	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	7.6	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	19.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	2.4	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	4.2	PID BMP PATHWAY	BMP receptor signaling
0.1	3.9	PID LKB1 PATHWAY	LKB1 signaling events
0.1	1.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	0.8	PID IFNG PATHWAY	IFN-gamma pathway
0.1	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.8	129.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
3.5	261.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
2.9	76.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
2.9	34.6	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
2.4	55.9	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
2.1	70.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
1.6	33.3	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
1.4	13.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
1.1	8.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.1	8.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
1.0	5.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.9	22.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.9	7.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.9	34.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.8	22.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.8	5.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.8	19.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.8	11.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.7	10.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.7	14.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.5	12.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.5	54.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.5	8.8	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.5	30.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.5	4.8	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.4	6.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.4	12.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.4	5.0	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.4	7.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.4	4.0	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.4	8.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.4	15.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.4	31.7	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.4	9.5	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3	7.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.3	6.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.3	9.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.3	4.8	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.3	5.7	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.3	6.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3	54.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.3	5.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.3	8.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.3	6.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.3	18.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3	7.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	9.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	4.6	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3	5.0	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.3	6.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3	26.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2	21.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2	15.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	3.8	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.2	4.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.2	4.4	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.2	43.1	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.2	8.9	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.2	4.0	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.2	1.5	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.2	4.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2	2.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.2	8.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.2	5.8	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.2	3.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	4.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.2	7.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2	14.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.2	4.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.2	3.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	2.8	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.2	1.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	3.1	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	2.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	3.9	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.1	3.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	4.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	3.6	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	1.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	4.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	5.8	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	3.9	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	9.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	2.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	0.6	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.1	2.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	1.1	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	12.7	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.1	2.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	9.0	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.1	15.0	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	2.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	2.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	2.2	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	1.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling