avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
PPARG Links Ensembl NCBI GeneCards UniProt	ENSG00000132170.24	PPARG

Gene	Promoter	Pearson corr. coef.	P-value	Plot
PPARG	hg38_v1_chr3_+_12289061_12289080	-0.12	8.7e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr22_+_22899481 Show fit	34.22	ENST00000390322.2	IGLJ2 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda joining 2
chr22_+_22922594 Show fit	33.88	ENST00000390331.3	IGLC7 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 7
chr19_-_10334723 Show fit	29.99	ENST00000592945.1	ICAM3 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr19_+_49513154 Show fit	29.54	ENST00000426395.7 ENST00000600273.5 ENST00000599988.5	FCGRT Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG receptor and transporter
chr11_+_308408 Show fit	23.67	ENST00000399815.2	ENSG00000288681.1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr22_+_22906342 Show fit	23.24	ENST00000390325.2	IGLC3 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr7_-_150801325 Show fit	21.67	ENST00000447204.6	TMEM176B Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 176B
chr1_+_203305510 Show fit	21.58	ENST00000290551.5	BTG2 Links Ensembl NCBI GeneCards UniProt Show fit	BTG anti-proliferation factor 2
chr22_+_22887780 Show fit	18.72	ENST00000532223.2 ENST00000526893.6 ENST00000531372.1	IGLL5 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda like polypeptide 5
chr19_-_35908247 Show fit	18.10	ENST00000585901.6 ENST00000544690.6 ENST00000424586.7 ENST00000262629.9 ENST00000589517.1	TYROBP Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane immune signaling adaptor TYROBP
chr11_+_308188 Show fit	17.65	ENST00000680619.1 ENST00000681833.1 ENST00000680261.1	IFITM2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced transmembrane protein 2
chr11_+_308106 Show fit	17.60	ENST00000399817.9 ENST00000680344.1	IFITM2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced transmembrane protein 2
chr11_+_314010 Show fit	17.18	ENST00000680699.1 ENST00000681938.1 ENST00000679380.1 ENST00000680938.1 ENST00000408968.4 ENST00000681180.1 ENST00000681426.1 ENST00000680696.1	IFITM1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced transmembrane protein 1
chr11_+_308217 Show fit	16.99	ENST00000602569.2	IFITM2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced transmembrane protein 2
chr17_-_64020566 Show fit	15.79	ENST00000578313.5 ENST00000584084.1 ENST00000579687.5 ENST00000578379.5 ENST00000578892.5 ENST00000579788.6 ENST00000412356.5 ENST00000418105.5	ICAM2 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 2
chr17_+_44350437 Show fit	15.67	ENST00000586443.1	GRN Links Ensembl NCBI GeneCards UniProt Show fit	granulin precursor
chr7_+_150801695 Show fit	15.31	ENST00000475536.5 ENST00000468689.2	TMEM176A Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 176A
chr22_+_22792485 Show fit	14.25	ENST00000390314.2	IGLV2-11 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-11
chr7_+_150801522 Show fit	13.93	ENST00000461345.5	TMEM176A Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 176A
chr19_+_49513353 Show fit	13.84	ENST00000596975.5	FCGRT Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG receptor and transporter
chr2_-_89010515 Show fit	13.70	ENST00000493819.1	IGKV1-9 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr22_+_22822658 Show fit	13.57	ENST00000620395.2	IGLV2-8 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-8
chr22_+_22588155 Show fit	13.52	ENST00000390302.3	IGLV2-33 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-33 (non-functional)
chr2_-_89143133 Show fit	13.06	ENST00000492167.1	IGKV3-20 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-20
chr10_-_70602759 Show fit	12.94	ENST00000373209.2	PRF1 Links Ensembl NCBI GeneCards UniProt Show fit	perforin 1
chr10_-_70602687 Show fit	12.30	ENST00000638674.1	PRF1 Links Ensembl NCBI GeneCards UniProt Show fit	perforin 1
chr22_+_22357739 Show fit	12.24	ENST00000390294.2	IGLV1-47 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-47
chr17_-_35880350 Show fit	12.20	ENST00000605140.6 ENST00000651122.1 ENST00000603197.6	CCL5 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 5
chr22_+_49918733 Show fit	12.01	ENST00000407217.7 ENST00000403427.3	CRELD2 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine rich with EGF like domains 2
chr14_+_105486867 Show fit	11.99	ENST00000409393.6 ENST00000392531.4	CRIP1 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine rich protein 1
chr10_-_70602731 Show fit	11.66	ENST00000441259.2	PRF1 Links Ensembl NCBI GeneCards UniProt Show fit	perforin 1
chr19_+_18173804 Show fit	11.58	ENST00000407280.4	IFI30 Links Ensembl NCBI GeneCards UniProt Show fit	IFI30 lysosomal thiol reductase
chr22_+_22758698 Show fit	11.21	ENST00000390312.2	IGLV2-14 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-14
chr14_+_105486311 Show fit	11.07	ENST00000330233.11	CRIP1 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine rich protein 1
chr22_+_49918626 Show fit	10.27	ENST00000328268.9 ENST00000404488.7	CRELD2 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine rich with EGF like domains 2
chr14_-_106875069 Show fit	10.18	ENST00000390639.2	IGHV7-81 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 7-81 (non-functional)
chr17_-_7394800 Show fit	10.06	ENST00000574401.5	PLSCR3 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 3
chr8_-_11868043 Show fit	9.98	ENST00000676843.1 ENST00000534510.6 ENST00000676825.1 ENST00000678145.1 ENST00000533455.6 ENST00000353047.11 ENST00000677650.1 ENST00000526195.6 ENST00000676691.1 ENST00000678598.1 ENST00000505496.7 ENST00000527215.7 ENST00000345125.8 ENST00000532656.7 ENST00000678067.1 ENST00000453527.7 ENST00000677415.1 ENST00000530640.7 ENST00000677418.1 ENST00000531089.6 ENST00000677544.1 ENST00000676502.1 ENST00000524500.6 ENST00000677873.1 ENST00000678629.1 ENST00000678929.1 ENST00000677819.1 ENST00000678357.1 ENST00000679051.1 ENST00000677082.1 ENST00000531502.6 ENST00000530296.6 ENST00000534636.6 ENST00000534149.6 ENST00000677366.1 ENST00000676755.1 ENST00000679140.1 ENST00000527243.6 ENST00000677047.1 ENST00000678242.1	CTSB Links Ensembl NCBI GeneCards UniProt Show fit	cathepsin B
chr2_-_89268506 Show fit	9.97	ENST00000473726.1	IGKV1-33 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-33
chr10_-_45594760 Show fit	9.96	ENST00000319836.7	MARCHF8 Links Ensembl NCBI GeneCards UniProt Show fit	membrane associated ring-CH-type finger 8
chr14_-_106411021 Show fit	9.91	ENST00000390618.2	IGHV3-38 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-38 (non-functional)
chr14_+_24161257 Show fit	9.63	ENST00000396864.8 ENST00000557894.5 ENST00000559284.5 ENST00000560275.5	IRF9 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 9
chr17_-_64020544 Show fit	9.51	ENST00000583366.5	ICAM2 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 2
chr1_+_158845798 Show fit	9.36	ENST00000438394.1	MNDA Links Ensembl NCBI GeneCards UniProt Show fit	myeloid cell nuclear differentiation antigen
chr14_-_105864247 Show fit	9.34	ENST00000461719.1	IGHJ4 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy joining 4
chr5_-_151080978 Show fit	9.32	ENST00000520931.5 ENST00000521591.6 ENST00000520695.5 ENST00000610535.5 ENST00000518977.5 ENST00000389378.6 ENST00000610874.4	TNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	TNFAIP3 interacting protein 1
chr14_-_106762576 Show fit	8.81	ENST00000624687.1	IGHV1-69D Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69D
chrX_-_107716401 Show fit	8.69	ENST00000486554.1 ENST00000372390.8	TSC22D3 Links Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 3
chr11_-_82901594 Show fit	8.43	ENST00000679623.1	PRCP Links Ensembl NCBI GeneCards UniProt Show fit	prolylcarboxypeptidase
chr2_+_85695368 Show fit	8.39	ENST00000526018.1	GNLY Links Ensembl NCBI GeneCards UniProt Show fit	granulysin
chr11_-_82901623 Show fit	8.32	ENST00000681637.1 ENST00000679387.1	PRCP Links Ensembl NCBI GeneCards UniProt Show fit	prolylcarboxypeptidase
chr17_-_7394514 Show fit	8.25	ENST00000571802.1 ENST00000619711.5 ENST00000576201.5 ENST00000573213.1 ENST00000324822.15	PLSCR3 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 3
chr6_-_158644709 Show fit	8.15	ENST00000367089.8	DYNLT1 Links Ensembl NCBI GeneCards UniProt Show fit	dynein light chain Tctex-type 1
chr1_-_159925496 Show fit	8.08	ENST00000368097.9	TAGLN2 Links Ensembl NCBI GeneCards UniProt Show fit	transgelin 2
chr17_-_7394240 Show fit	7.92	ENST00000576362.5 ENST00000571078.5	PLSCR3 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 3
chr19_+_18571730 Show fit	7.84	ENST00000596304.5 ENST00000430157.6 ENST00000596273.5 ENST00000442744.7 ENST00000595683.5 ENST00000599256.5 ENST00000595158.5 ENST00000598780.5	UBA52 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin A-52 residue ribosomal protein fusion product 1
chr9_+_99222258 Show fit	7.80	ENST00000223641.5	SEC61B Links Ensembl NCBI GeneCards UniProt Show fit	SEC61 translocon subunit beta
chr6_+_31815532 Show fit	7.72	ENST00000375651.7 ENST00000608703.1	HSPA1A Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family A (Hsp70) member 1A
chr11_-_5234475 Show fit	7.70	ENST00000292901.7 ENST00000650601.1 ENST00000417377.1	HBD Links Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit delta
chr16_+_29820394 Show fit	7.52	ENST00000563915.5 ENST00000395353.5	MVP Links Ensembl NCBI GeneCards UniProt Show fit	major vault protein
chr19_+_41884370 Show fit	7.47	ENST00000378152.8 ENST00000337665.8	ARHGEF1 Links Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 1
chr15_+_69452811 Show fit	7.46	ENST00000357790.5 ENST00000260379.11 ENST00000560274.1	RPLP1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein lateral stalk subunit P1
chr22_+_22380766 Show fit	6.82	ENST00000390297.3	IGLV1-44 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-44
chr16_+_55479188 Show fit	6.76	ENST00000219070.9	MMP2 Links Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 2
chr22_-_36387949 Show fit	6.61	ENST00000216181.11	MYH9 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 9
chr17_+_47209375 Show fit	6.59	ENST00000572303.1	MYL4 Links Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr22_+_22327298 Show fit	6.51	ENST00000390291.2	IGLV1-50 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-50 (non-functional)
chr14_-_100376251 Show fit	6.47	ENST00000556645.5 ENST00000556209.5 ENST00000556504.5 ENST00000556435.5 ENST00000554772.5 ENST00000553581.1 ENST00000553769.6 ENST00000554605.5 ENST00000557722.5 ENST00000553413.5 ENST00000553524.5 ENST00000358655.8	WARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr11_-_60952067 Show fit	6.42	ENST00000681275.1	SLC15A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 15 member 3
chr19_+_1407517 Show fit	6.36	ENST00000336761.10 ENST00000233078.9 ENST00000592522.5	DAZAP1 Links Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 1
chr16_+_29820436 Show fit	6.15	ENST00000357402.10 ENST00000566066.5 ENST00000563558.5	MVP Links Ensembl NCBI GeneCards UniProt Show fit	major vault protein
chr17_-_82333751 Show fit	6.03	ENST00000580437.5 ENST00000583093.5 ENST00000269389.8 ENST00000582290.5 ENST00000582563.5	SECTM1 Links Ensembl NCBI GeneCards UniProt Show fit	secreted and transmembrane 1
chr1_+_159015665 Show fit	5.90	ENST00000567661.5 ENST00000474473.1	IFI16 Links Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr11_+_117199363 Show fit	5.58	ENST00000392951.9 ENST00000525531.5 ENST00000278968.10	TAGLN Links Ensembl NCBI GeneCards UniProt Show fit	transgelin
chr19_+_17859885 Show fit	5.55	ENST00000222247.10 ENST00000600147.5 ENST00000599898.5	RPL18A Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L18a
chr11_+_2902388 Show fit	5.48	ENST00000380574.5	SLC22A18 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 18
chr22_+_22322452 Show fit	5.37	ENST00000390290.3	IGLV1-51 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-51
chr4_+_15703057 Show fit	5.34	ENST00000265016.9 ENST00000382346.7	BST1 Links Ensembl NCBI GeneCards UniProt Show fit	bone marrow stromal cell antigen 1
chr6_+_292050 Show fit	5.32	ENST00000344450.9	DUSP22 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 22
chr12_+_49741544 Show fit	5.32	ENST00000549966.5 ENST00000547832.5 ENST00000547187.5 ENST00000548894.5 ENST00000546914.5 ENST00000552699.5 ENST00000267115.10	TMBIM6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr11_-_60952559 Show fit	5.30	ENST00000538739.2	SLC15A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 15 member 3
chr3_-_146544701 Show fit	5.27	ENST00000487389.5	PLSCR1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr22_+_22409755 Show fit	5.14	ENST00000390299.2	IGLV1-40 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-40
chr16_+_30372291 Show fit	5.12	ENST00000568749.5	MYLPF Links Ensembl NCBI GeneCards UniProt Show fit	myosin light chain, phosphorylatable, fast skeletal muscle
chr11_+_75815180 Show fit	5.11	ENST00000356136.8	UVRAG Links Ensembl NCBI GeneCards UniProt Show fit	UV radiation resistance associated
chr1_+_207321532 Show fit	5.11	ENST00000367063.6 ENST00000391921.9 ENST00000645323.1	CD55 Links Ensembl NCBI GeneCards UniProt Show fit	CD55 molecule (Cromer blood group)
chr9_+_137086857 Show fit	5.05	ENST00000682881.1 ENST00000683324.1 ENST00000542372.2 ENST00000683355.1 ENST00000682117.1 ENST00000682212.1 ENST00000684144.1 ENST00000683987.1 ENST00000371589.9 ENST00000535144.6 ENST00000475449.7 ENST00000684759.1	MAN1B1 Links Ensembl NCBI GeneCards UniProt Show fit	mannosidase alpha class 1B member 1
chr2_+_201129483 Show fit	5.01	ENST00000440180.5	CFLAR Links Ensembl NCBI GeneCards UniProt Show fit	CASP8 and FADD like apoptosis regulator
chr19_+_544034 Show fit	5.01	ENST00000592501.5 ENST00000264553.6	GZMM Links Ensembl NCBI GeneCards UniProt Show fit	granzyme M
chr2_+_30146993 Show fit	5.01	ENST00000261353.9 ENST00000402003.7	YPEL5 Links Ensembl NCBI GeneCards UniProt Show fit	yippee like 5
chr1_+_207752046 Show fit	5.00	ENST00000367042.6 ENST00000322875.8 ENST00000322918.9 ENST00000354848.5 ENST00000357714.5 ENST00000358170.6 ENST00000367041.5 ENST00000367047.5 ENST00000360212.6 ENST00000480003.5	CD46 Links Ensembl NCBI GeneCards UniProt Show fit	CD46 molecule
chr19_-_43527189 Show fit	4.99	ENST00000292147.7 ENST00000600651.5	ETHE1 Links Ensembl NCBI GeneCards UniProt Show fit	ETHE1 persulfide dioxygenase
chr2_-_218286763 Show fit	4.98	ENST00000444881.5	TMBIM1 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 1
chr1_+_207321668 Show fit	4.96	ENST00000367064.9 ENST00000314754.12 ENST00000367067.8 ENST00000644836.1 ENST00000343420.6	CD55 Links Ensembl NCBI GeneCards UniProt Show fit	CD55 molecule (Cromer blood group)
chr11_-_60952134 Show fit	4.94	ENST00000679573.1 ENST00000681882.1 ENST00000681951.1 ENST00000227880.8	SLC15A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 15 member 3
chr19_-_13102848 Show fit	4.88	ENST00000264824.5	LYL1 Links Ensembl NCBI GeneCards UniProt Show fit	LYL1 basic helix-loop-helix family member
chr17_+_47209338 Show fit	4.79	ENST00000393450.5	MYL4 Links Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr2_+_201129318 Show fit	4.75	ENST00000417748.1	CFLAR Links Ensembl NCBI GeneCards UniProt Show fit	CASP8 and FADD like apoptosis regulator
chr2_+_30146941 Show fit	4.73	ENST00000379520.7 ENST00000379519.7	YPEL5 Links Ensembl NCBI GeneCards UniProt Show fit	yippee like 5
chr12_-_55728994 Show fit	4.68	ENST00000257857.9	CD63 Links Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chr4_-_867162 Show fit	4.67	ENST00000511980.5 ENST00000510799.1	GAK Links Ensembl NCBI GeneCards UniProt Show fit	cyclin G associated kinase
chr7_-_99971845 Show fit	4.63	ENST00000419575.1	AZGP1 Links Ensembl NCBI GeneCards UniProt Show fit	alpha-2-glycoprotein 1, zinc-binding
chr9_-_127916978 Show fit	4.62	ENST00000361444.3 ENST00000335791.10	ST6GALNAC4 Links Ensembl NCBI GeneCards UniProt Show fit	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr3_+_33798557 Show fit	4.60	ENST00000457054.6 ENST00000413073.1 ENST00000307296.8	PDCD6IP Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 6 interacting protein
chr7_+_76303547 Show fit	4.52	ENST00000429938.1	HSPB1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 1
chr17_-_41786688 Show fit	4.50	ENST00000310706.9 ENST00000393931.8 ENST00000424457.5 ENST00000591690.5	JUP Links Ensembl NCBI GeneCards UniProt Show fit	junction plakoglobin
chr20_+_833734 Show fit	4.42	ENST00000304189.6	FAM110A Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 110 member A
chr12_+_49741565 Show fit	4.41	ENST00000549445.5 ENST00000550951.5 ENST00000549385.5 ENST00000548713.5 ENST00000548201.5	TMBIM6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr4_+_86934976 Show fit	4.40	ENST00000507468.5 ENST00000395146.9	AFF1 Links Ensembl NCBI GeneCards UniProt Show fit	AF4/FMR2 family member 1
chr17_+_42289213 Show fit	4.30	ENST00000677301.1	STAT5A Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr15_+_90388234 Show fit	4.28	ENST00000268182.10 ENST00000560738.1 ENST00000560418.1	IQGAP1 Links Ensembl NCBI GeneCards UniProt Show fit	IQ motif containing GTPase activating protein 1
chr19_-_50837213 Show fit	4.06	ENST00000326856.8	KLK15 Links Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 15
chr14_+_22494810 Show fit	4.04	ENST00000390493.1	TRAJ44 Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 44
chr17_-_64506616 Show fit	3.94	ENST00000581697.5 ENST00000450599.7 ENST00000577922.6	DDX5 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 5
chr6_-_111793871 Show fit	3.85	ENST00000368667.6	FYN Links Ensembl NCBI GeneCards UniProt Show fit	FYN proto-oncogene, Src family tyrosine kinase
chr1_-_19484635 Show fit	3.82	ENST00000433834.5	CAPZB Links Ensembl NCBI GeneCards UniProt Show fit	capping actin protein of muscle Z-line subunit beta
chr6_+_31827730 Show fit	3.74	ENST00000375650.5	HSPA1B Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family A (Hsp70) member 1B
chr19_+_49361783 Show fit	3.74	ENST00000594268.1	DKKL1 Links Ensembl NCBI GeneCards UniProt Show fit	dickkopf like acrosomal protein 1
chr6_-_112254555 Show fit	3.72	ENST00000230538.12 ENST00000389463.9 ENST00000368638.5 ENST00000431543.6 ENST00000453937.2	LAMA4 Links Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 4
chr10_+_112376193 Show fit	3.69	ENST00000433418.6 ENST00000356116.6 ENST00000354273.5	ACSL5 Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long chain family member 5
chr9_-_136203183 Show fit	3.69	ENST00000371746.9	LHX3 Links Ensembl NCBI GeneCards UniProt Show fit	LIM homeobox 3
chr3_+_48466222 Show fit	3.64	ENST00000625293.3 ENST00000492235.2 ENST00000635452.2 ENST00000456089.1	TREX1 Links Ensembl NCBI GeneCards UniProt Show fit	three prime repair exonuclease 1
chr6_-_112254647 Show fit	3.60	ENST00000455073.1 ENST00000522006.5 ENST00000519932.5	LAMA4 Links Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 4
chr16_-_4416621 Show fit	3.58	ENST00000570645.5 ENST00000574025.5 ENST00000572898.1 ENST00000537233.6 ENST00000571059.5	CORO7 Links Ensembl NCBI GeneCards UniProt Show fit	coronin 7
chr19_-_5622768 Show fit	3.44	ENST00000252542.9	SAFB2 Links Ensembl NCBI GeneCards UniProt Show fit	scaffold attachment factor B2
chr17_+_48831021 Show fit	3.43	ENST00000509507.5 ENST00000448105.6 ENST00000570513.5 ENST00000509415.5 ENST00000513119.5 ENST00000416445.6 ENST00000508679.5 ENST00000258947.8 ENST00000505071.5	CALCOCO2 Links Ensembl NCBI GeneCards UniProt Show fit	calcium binding and coiled-coil domain 2
chr3_+_48465811 Show fit	3.33	ENST00000433541.1 ENST00000444177.1	TREX1 Links Ensembl NCBI GeneCards UniProt Show fit	three prime repair exonuclease 1
chr10_+_133379238 Show fit	3.29	ENST00000357296.7 ENST00000278060.10	PAOX Links Ensembl NCBI GeneCards UniProt Show fit	polyamine oxidase
chr18_+_58671517 Show fit	3.27	ENST00000345724.7	MALT1 Links Ensembl NCBI GeneCards UniProt Show fit	MALT1 paracaspase
chr4_-_932373 Show fit	3.25	ENST00000511163.5	GAK Links Ensembl NCBI GeneCards UniProt Show fit	cyclin G associated kinase
chr1_+_10399054 Show fit	3.22	ENST00000270776.13 ENST00000483936.5	PGD Links Ensembl NCBI GeneCards UniProt Show fit	phosphogluconate dehydrogenase
chr14_-_100375602 Show fit	3.19	ENST00000553395.5 ENST00000553545.5 ENST00000344102.9 ENST00000556338.5 ENST00000553934.1	WARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr16_-_4937064 Show fit	3.11	ENST00000590782.6 ENST00000345988.7	PPL Links Ensembl NCBI GeneCards UniProt Show fit	periplakin
chr19_+_2269520 Show fit	3.08	ENST00000602676.6 ENST00000582888.8	OAZ1 Links Ensembl NCBI GeneCards UniProt Show fit	ornithine decarboxylase antizyme 1
chr6_-_31815244 Show fit	3.04	ENST00000375654.5	HSPA1L Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family A (Hsp70) member 1 like
chr6_+_26383176 Show fit	3.02	ENST00000416795.6 ENST00000494184.1	BTN2A2 Links Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 2 member A2
chr9_+_121286115 Show fit	3.01	ENST00000477104.2 ENST00000394353.7	GSN Links Ensembl NCBI GeneCards UniProt Show fit	gelsolin
chr8_+_30095400 Show fit	2.96	ENST00000321250.13 ENST00000518001.1 ENST00000520682.5 ENST00000442880.6 ENST00000523116.5	LEPROTL1 Links Ensembl NCBI GeneCards UniProt Show fit	leptin receptor overlapping transcript like 1
chr19_+_7903843 Show fit	2.96	ENST00000397981.7 ENST00000397979.4 ENST00000397983.7	MAP2K7 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase 7
chr11_-_67443459 Show fit	2.96	ENST00000341356.10 ENST00000627576.2	CORO1B Links Ensembl NCBI GeneCards UniProt Show fit	coronin 1B
chr8_+_69492793 Show fit	2.95	ENST00000616868.1 ENST00000419716.7 ENST00000402687.9	SULF1 Links Ensembl NCBI GeneCards UniProt Show fit	sulfatase 1
chr11_-_14643617 Show fit	2.83	ENST00000418988.2	PSMA1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 1
chr6_-_112254485 Show fit	2.77	ENST00000521398.5 ENST00000424408.6 ENST00000243219.7	LAMA4 Links Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 4
chr9_-_71768386 Show fit	2.74	ENST00000377066.9 ENST00000377044.9	CEMIP2 Links Ensembl NCBI GeneCards UniProt Show fit	cell migration inducing hyaluronidase 2
chr20_+_45934670 Show fit	2.73	ENST00000372409.8	PCIF1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphorylated CTD interacting factor 1
chr8_+_11494367 Show fit	2.66	ENST00000259089.9 ENST00000529894.1	BLK Links Ensembl NCBI GeneCards UniProt Show fit	BLK proto-oncogene, Src family tyrosine kinase
chr6_-_168101506 Show fit	2.65	ENST00000644440.1	FRMD1 Links Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 1
chr19_+_51142299 Show fit	2.63	ENST00000601682.1 ENST00000317643.10 ENST00000305628.7 ENST00000600577.1	SIGLEC7 Links Ensembl NCBI GeneCards UniProt Show fit	sialic acid binding Ig like lectin 7
chr14_+_24429932 Show fit	2.60	ENST00000556842.5 ENST00000553935.6	KHNYN Links Ensembl NCBI GeneCards UniProt Show fit	KH and NYN domain containing
chrX_+_9543103 Show fit	2.60	ENST00000683056.1	TBL1X Links Ensembl NCBI GeneCards UniProt Show fit	transducin beta like 1 X-linked
chr20_+_36236433 Show fit	2.57	ENST00000397286.7 ENST00000679519.1 ENST00000679667.1 ENST00000680933.1 ENST00000680247.1 ENST00000320849.9 ENST00000680811.1 ENST00000373932.3	AAR2 Links Ensembl NCBI GeneCards UniProt Show fit	AAR2 splicing factor
chr3_-_146544578 Show fit	2.54	ENST00000342435.9 ENST00000448787.6	PLSCR1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr22_+_22747383 Show fit	2.53	ENST00000390311.3	IGLV3-16 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-16
chr6_+_31498136 Show fit	2.52	ENST00000252229.7	MICB Links Ensembl NCBI GeneCards UniProt Show fit	MHC class I polypeptide-related sequence B
chr16_-_18896874 Show fit	2.50	ENST00000565324.5 ENST00000561947.5	SMG1 Links Ensembl NCBI GeneCards UniProt Show fit	SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr19_+_1438384 Show fit	2.50	ENST00000586686.6 ENST00000592588.7 ENST00000591032.1 ENST00000592623.5 ENST00000586656.5 ENST00000589656.6 ENST00000591804.6 ENST00000593052.5 ENST00000586096.3 ENST00000617694.4 ENST00000585665.2	RPS15 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S15
chr19_-_50823778 Show fit	2.49	ENST00000301420.3	KLK1 Links Ensembl NCBI GeneCards UniProt Show fit	kallikrein 1
chr3_+_52777580 Show fit	2.48	ENST00000273283.7	ITIH1 Links Ensembl NCBI GeneCards UniProt Show fit	inter-alpha-trypsin inhibitor heavy chain 1
chr17_+_28744034 Show fit	2.48	ENST00000444415.7 ENST00000262396.10	TRAF4 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 4
chr19_+_850985 Show fit	2.46	ENST00000590230.5	ELANE Links Ensembl NCBI GeneCards UniProt Show fit	elastase, neutrophil expressed
chr19_+_35118456 Show fit	2.38	ENST00000604621.5	FXYD3 Links Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 3
chr22_-_21225554 Show fit	2.38	ENST00000405188.8	GGT2 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyltransferase 2
chr9_-_127854636 Show fit	2.33	ENST00000344849.4 ENST00000373203.9	ENG Links Ensembl NCBI GeneCards UniProt Show fit	endoglin
chr3_+_9917074 Show fit	2.33	ENST00000416074.6 ENST00000383812.9 ENST00000438091.5 ENST00000295981.7 ENST00000403601.8 ENST00000436503.5 ENST00000455057.5	IL17RC Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 17 receptor C
chr3_+_48241046 Show fit	2.32	ENST00000427617.6 ENST00000412564.5 ENST00000354698.8 ENST00000440261.6	ZNF589 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 589
chr2_+_233354474 Show fit	2.31	ENST00000264057.7 ENST00000427930.5 ENST00000442524.4	DGKD Links Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase delta
chr13_-_43879696 Show fit	2.30	ENST00000444614.8	CCDC122 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 122
chr19_-_51387955 Show fit	2.27	ENST00000221973.7 ENST00000596399.2	LIM2 Links Ensembl NCBI GeneCards UniProt Show fit	lens intrinsic membrane protein 2
chr3_-_146544636 Show fit	2.26	ENST00000486631.5	PLSCR1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr1_-_112704921 Show fit	2.26	ENST00000414971.1 ENST00000534717.5	RHOC Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member C
chr2_-_216860042 Show fit	2.26	ENST00000236979.2	TNP1 Links Ensembl NCBI GeneCards UniProt Show fit	transition protein 1
chr10_-_97292625 Show fit	2.25	ENST00000466484.1 ENST00000358531.9 ENST00000358308.7	ARHGAP19 Links Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 19
chr19_-_1592794 Show fit	2.24	ENST00000156825.5	MBD3 Links Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding domain protein 3
chr8_+_144504131 Show fit	2.23	ENST00000394955.3	GPT Links Ensembl NCBI GeneCards UniProt Show fit	glutamic--pyruvic transaminase
chr19_+_1438351 Show fit	2.23	ENST00000233609.8	RPS15 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S15
chr16_+_20901059 Show fit	2.22	ENST00000396052.3	LYRM1 Links Ensembl NCBI GeneCards UniProt Show fit	LYR motif containing 1
chr19_-_51723968 Show fit	2.21	ENST00000222115.5 ENST00000540069.7	HAS1 Links Ensembl NCBI GeneCards UniProt Show fit	hyaluronan synthase 1
chr6_+_43427535 Show fit	2.18	ENST00000372530.9	ABCC10 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily C member 10
chr6_+_31498071 Show fit	2.17	ENST00000399150.7	MICB Links Ensembl NCBI GeneCards UniProt Show fit	MHC class I polypeptide-related sequence B
chr17_-_18258556 Show fit	2.14	ENST00000579294.5 ENST00000628188.1 ENST00000545457.6 ENST00000578558.5 ENST00000327031.9	FLII Links Ensembl NCBI GeneCards UniProt Show fit	FLII actin remodeling protein
chr3_+_9917185 Show fit	2.10	ENST00000413608.2 ENST00000451165.6	IL17RC Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 17 receptor C
chr19_-_1592829 Show fit	2.08	ENST00000434436.8	MBD3 Links Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding domain protein 3
chr17_-_7179348 Show fit	2.05	ENST00000573083.1 ENST00000574388.5 ENST00000269299.8	ASGR1 Links Ensembl NCBI GeneCards UniProt Show fit	asialoglycoprotein receptor 1
chr2_+_232550643 Show fit	2.04	ENST00000409514.5 ENST00000409098.5 ENST00000409495.5 ENST00000409167.7 ENST00000258416.8 ENST00000409322.5 ENST00000409394.5 ENST00000454501.1	EIF4E2 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4E family member 2
chr1_-_160862880 Show fit	2.04	ENST00000368034.9	CD244 Links Ensembl NCBI GeneCards UniProt Show fit	CD244 molecule
chr5_-_179623659 Show fit	2.03	ENST00000519056.5 ENST00000506721.5 ENST00000503105.5 ENST00000504348.5 ENST00000508103.5 ENST00000510431.5 ENST00000515158.5 ENST00000393432.8 ENST00000442819.6	HNRNPH1 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein H1
chr16_+_20900753 Show fit	2.01	ENST00000219168.8 ENST00000567954.6	LYRM1 Links Ensembl NCBI GeneCards UniProt Show fit	LYR motif containing 1
chr3_+_46354072 Show fit	1.96	ENST00000445132.3 ENST00000421659.1	CCR2 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine receptor 2
chr3_+_8733779 Show fit	1.96	ENST00000343849.3 ENST00000397368.2	CAV3 Links Ensembl NCBI GeneCards UniProt Show fit	caveolin 3
chr6_-_49744434 Show fit	1.92	ENST00000433368.6 ENST00000354620.4	CRISP3 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine rich secretory protein 3
chr16_+_85613252 Show fit	1.91	ENST00000253458.12 ENST00000393243.5	GSE1 Links Ensembl NCBI GeneCards UniProt Show fit	Gse1 coiled-coil protein
chr20_+_45174894 Show fit	1.87	ENST00000243924.4	PI3 Links Ensembl NCBI GeneCards UniProt Show fit	peptidase inhibitor 3
chr17_-_7179544 Show fit	1.86	ENST00000619926.4	ASGR1 Links Ensembl NCBI GeneCards UniProt Show fit	asialoglycoprotein receptor 1
chr14_-_100375333 Show fit	1.85	ENST00000557297.5 ENST00000555813.5 ENST00000392882.7 ENST00000557135.5 ENST00000556698.5 ENST00000554509.5 ENST00000555410.5	WARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr16_+_68264501 Show fit	1.85	ENST00000618043.4 ENST00000219343.11 ENST00000566834.5 ENST00000566454.5	SLC7A6 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 6
chr1_+_170664121 Show fit	1.84	ENST00000239461.11	PRRX1 Links Ensembl NCBI GeneCards UniProt Show fit	paired related homeobox 1
chr11_+_14643826 Show fit	1.83	ENST00000455098.2	PDE3B Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 3B
chr17_+_82752042 Show fit	1.80	ENST00000682479.1 ENST00000682722.1 ENST00000684464.1 ENST00000684544.1 ENST00000683282.1 ENST00000684408.1 ENST00000355528.9 ENST00000684760.1 ENST00000684349.1 ENST00000539345.6 ENST00000684000.1	TBCD Links Ensembl NCBI GeneCards UniProt Show fit	tubulin folding cofactor D
chr17_+_28744002 Show fit	1.79	ENST00000618771.1 ENST00000262395.10 ENST00000422344.5	TRAF4 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 4
chr8_-_144901414 Show fit	1.73	ENST00000533221.5 ENST00000525694.5 ENST00000533622.5 ENST00000417550.7 ENST00000292579.11	ZNF250 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 250

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.5	43.4	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
9.2	36.9	GO:0002357	defense response to tumor cell(GO:0002357)
6.6	6.6	GO:1903923	protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
5.8	23.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
3.9	50.9	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
3.0	12.2	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.9	11.5	GO:0070426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.8	8.4	GO:0002818	intracellular defense response(GO:0002818)
2.5	72.4	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
2.1	38.7	GO:0017121	phospholipid scrambling(GO:0017121)
2.1	16.7	GO:0002254	kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
2.0	7.9	GO:1905224	clathrin-coated pit assembly(GO:1905224)
1.7	5.1	GO:0051684	maintenance of Golgi location(GO:0051684)
1.7	5.1	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
1.7	5.1	GO:0036510	trimming of terminal mannose on C branch(GO:0036510)
1.7	10.1	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
1.6	9.7	GO:1904720	regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.6	7.8	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
1.5	4.6	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
1.4	8.2	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.4	6.8	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.2	5.0	GO:0070221	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
1.2	4.9	GO:0099640	axo-dendritic protein transport(GO:0099640)
1.2	175.7	GO:0006958	complement activation, classical pathway(GO:0006958)
1.1	18.1	GO:2001204	regulation of osteoclast development(GO:2001204)
1.1	3.3	GO:0009447	putrescine catabolic process(GO:0009447)
1.1	3.3	GO:0001923	B-1 B cell differentiation(GO:0001923)
1.1	8.7	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.0	2.0	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
1.0	5.0	GO:2000504	regulation of Fas signaling pathway(GO:1902044) positive regulation of blood vessel remodeling(GO:2000504)
1.0	21.6	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
1.0	2.0	GO:0002436	immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.9	16.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.9	9.8	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.8	9.3	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.8	3.2	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.8	5.5	GO:0046618	drug export(GO:0046618)
0.7	2.2	GO:0009080	alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.7	3.0	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.7	4.7	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.7	4.0	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.6	4.4	GO:0097396	response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.6	3.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.6	4.3	GO:0000255	allantoin metabolic process(GO:0000255)
0.6	3.7	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.6	3.4	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.5	3.8	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.5	1.5	GO:0002461	tolerance induction dependent upon immune response(GO:0002461) regulation of thymocyte migration(GO:2000410)
0.5	7.8	GO:0017085	response to insecticide(GO:0017085)
0.5	1.4	GO:2000360	negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.5	2.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.4	4.9	GO:0001955	blood vessel maturation(GO:0001955)
0.4	4.7	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.4	9.4	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.4	3.0	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.4	1.7	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.4	10.3	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.4	7.7	GO:0015671	oxygen transport(GO:0015671)
0.4	2.4	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.4	2.0	GO:0035995	detection of muscle stretch(GO:0035995)
0.4	16.3	GO:0001893	maternal placenta development(GO:0001893)
0.4	0.8	GO:0043605	cellular amide catabolic process(GO:0043605)
0.4	5.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.4	1.5	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.4	1.1	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.4	1.1	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.4	2.9	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.3	1.4	GO:0006542	glutamine biosynthetic process(GO:0006542)
0.3	1.0	GO:0098758	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.3	4.7	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.3	1.3	GO:0003095	pressure natriuresis(GO:0003095)
0.3	3.0	GO:0035897	proteolysis in other organism(GO:0035897)
0.3	2.3	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3	55.0	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.3	3.9	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3	11.4	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.3	0.9	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.3	11.6	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.3	4.3	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.3	1.8	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.3	3.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.3	4.3	GO:0090073	activation of NF-kappaB-inducing kinase activity(GO:0007250) positive regulation of protein homodimerization activity(GO:0090073)
0.2	35.7	GO:0002377	immunoglobulin production(GO:0002377)
0.2	0.9	GO:0060023	soft palate development(GO:0060023)
0.2	2.6	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2	5.3	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
0.2	2.4	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2	7.8	GO:0006298	mismatch repair(GO:0006298)
0.2	4.6	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	0.5	GO:0032679	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.2	0.3	GO:0035419	activation of MAPK activity involved in innate immune response(GO:0035419)
0.2	3.6	GO:0006895	Golgi to endosome transport(GO:0006895)
0.2	1.8	GO:0048664	neuron fate determination(GO:0048664)
0.2	1.2	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.1	5.9	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
0.1	7.0	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.7	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1	0.5	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	3.4	GO:0060008	Sertoli cell differentiation(GO:0060008)
0.1	3.7	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	2.7	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.1	1.0	GO:0051014	actin filament severing(GO:0051014)
0.1	1.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	2.3	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	12.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	3.0	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.1	9.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.1	0.9	GO:0060992	response to fungicide(GO:0060992)
0.1	3.1	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1	3.8	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	0.9	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.1	2.5	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	0.4	GO:0034587	piRNA metabolic process(GO:0034587)
0.1	1.1	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.1	3.1	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.1	0.6	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.2	GO:0036047	protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
0.0	0.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	1.7	GO:0019835	cytolysis(GO:0019835)
0.0	2.5	GO:0006968	cellular defense response(GO:0006968)
0.0	5.2	GO:0070268	cornification(GO:0070268)
0.0	0.8	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	2.1	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.0	0.4	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.6	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	21.0	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	1.8	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	0.6	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	2.5	GO:0032204	regulation of telomere maintenance(GO:0032204)
0.0	5.2	GO:0007498	mesoderm development(GO:0007498)
0.0	2.1	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0	0.3	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	6.0	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.0	0.2	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.8	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.5	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	1.4	GO:0042733	embryonic digit morphogenesis(GO:0042733)
0.0	2.4	GO:0016575	histone deacetylation(GO:0016575)
0.0	3.1	GO:0002576	platelet degranulation(GO:0002576)
0.0	0.4	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.5	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.5	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.7	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0	0.3	GO:0030728	ovulation(GO:0030728)
0.0	1.6	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0	0.3	GO:0014850	response to muscle activity(GO:0014850)
0.0	2.1	GO:0006413	translational initiation(GO:0006413)
0.0	0.8	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.2	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.5	45.3	GO:0044194	cytolytic granule(GO:0044194)
4.4	13.1	GO:0071753	IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
1.7	37.3	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
1.7	5.0	GO:0002079	inner acrosomal membrane(GO:0002079)
1.6	79.1	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
1.6	7.8	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
1.4	10.0	GO:0036021	endolysosome lumen(GO:0036021)
0.8	2.3	GO:0072563	endothelial microparticle(GO:0072563)
0.7	3.3	GO:0032449	CBM complex(GO:0032449)
0.5	3.8	GO:0008290	F-actin capping protein complex(GO:0008290)
0.5	7.7	GO:0005833	hemoglobin complex(GO:0005833)
0.5	1.4	GO:0030312	external encapsulating structure(GO:0030312)
0.5	9.8	GO:0097342	ripoptosome(GO:0097342)
0.4	12.9	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.4	5.1	GO:0030897	HOPS complex(GO:0030897)
0.4	4.7	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.4	62.7	GO:0072562	blood microparticle(GO:0072562)
0.3	4.5	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.3	4.3	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3	4.6	GO:0090543	Flemming body(GO:0090543)
0.3	2.3	GO:0000788	nuclear nucleosome(GO:0000788)
0.3	8.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.3	0.9	GO:0032426	stereocilium tip(GO:0032426)
0.3	1.2	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.3	0.9	GO:0005592	collagen type XI trimer(GO:0005592)
0.3	16.7	GO:0035577	azurophil granule membrane(GO:0035577)
0.3	0.8	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2	3.1	GO:0017119	Golgi transport complex(GO:0017119)
0.2	2.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.2	2.8	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.2	5.1	GO:0005859	muscle myosin complex(GO:0005859)
0.2	24.6	GO:0035578	azurophil granule lumen(GO:0035578)
0.2	1.1	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2	3.9	GO:0071141	SMAD protein complex(GO:0071141)
0.2	13.4	GO:1904724	tertiary granule lumen(GO:1904724)
0.2	4.9	GO:0000421	autophagosome membrane(GO:0000421)
0.1	1.8	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	11.4	GO:0031672	A band(GO:0031672)
0.1	2.0	GO:0005845	mRNA cap binding complex(GO:0005845)
0.1	13.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	4.3	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	13.7	GO:0005643	nuclear pore(GO:0005643)
0.1	5.0	GO:0001533	cornified envelope(GO:0001533)
0.1	0.6	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1	9.6	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	0.4	GO:1990075	periciliary membrane compartment(GO:1990075)
0.1	0.4	GO:0071546	pi-body(GO:0071546)
0.1	2.3	GO:0032420	stereocilium(GO:0032420)
0.1	0.5	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	4.5	GO:1904115	axon cytoplasm(GO:1904115)
0.1	1.4	GO:0005662	DNA replication factor A complex(GO:0005662)
0.1	5.5	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	4.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	3.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	18.7	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1	2.0	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.9	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.5	GO:0005614	interstitial matrix(GO:0005614)
0.0	62.9	GO:0005615	extracellular space(GO:0005615)
0.0	17.1	GO:0031965	nuclear membrane(GO:0031965)
0.0	6.4	GO:0005884	actin filament(GO:0005884)
0.0	0.8	GO:0031528	microvillus membrane(GO:0031528)
0.0	13.4	GO:0030667	secretory granule membrane(GO:0030667)
0.0	2.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.2	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	4.4	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	7.5	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	2.7	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	2.0	GO:0043204	perikaryon(GO:0043204)
0.0	0.6	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.7	GO:0048786	presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.8	43.4	GO:0019770	IgG receptor activity(GO:0019770)
2.8	16.7	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
2.4	12.2	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
2.4	38.7	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.9	11.4	GO:0032038	myosin II heavy chain binding(GO:0032038)
1.5	4.6	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.5	4.5	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
1.4	9.7	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
1.4	5.5	GO:0015307	drug:proton antiporter activity(GO:0015307)
1.4	23.1	GO:0003680	AT DNA binding(GO:0003680)
1.3	79.1	GO:0034987	immunoglobulin receptor binding(GO:0034987)
1.2	7.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
1.1	7.8	GO:0048408	epidermal growth factor binding(GO:0048408)
1.1	3.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.0	11.5	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
1.0	26.4	GO:0022829	wide pore channel activity(GO:0022829)
1.0	3.9	GO:0035500	MH2 domain binding(GO:0035500)
1.0	8.7	GO:0043426	MRF binding(GO:0043426)
0.9	4.6	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.8	3.3	GO:0046592	polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.8	16.7	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.8	3.9	GO:0042610	CD8 receptor binding(GO:0042610)
0.7	2.9	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7	2.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.7	127.6	GO:0003823	antigen binding(GO:0003823)
0.7	2.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.6	4.4	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.6	5.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6	3.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.6	1.8	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.6	4.7	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.6	4.5	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.6	3.9	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.5	7.7	GO:0005344	oxygen transporter activity(GO:0005344)
0.5	2.0	GO:0071253	connexin binding(GO:0071253)
0.4	14.7	GO:0005123	death receptor binding(GO:0005123)
0.4	3.0	GO:0045159	myosin II binding(GO:0045159)
0.4	3.0	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.3	1.4	GO:0004356	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3	1.0	GO:0019959	interleukin-8 binding(GO:0019959)
0.3	6.6	GO:0043495	protein anchor(GO:0043495)
0.3	1.2	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.3	6.4	GO:0035613	RNA stem-loop binding(GO:0035613)
0.3	13.6	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.3	2.3	GO:0005534	galactose binding(GO:0005534)
0.3	50.1	GO:0005178	integrin binding(GO:0005178)
0.3	1.1	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.3	11.1	GO:0043394	proteoglycan binding(GO:0043394)
0.3	0.8	GO:0070573	metallodipeptidase activity(GO:0070573)
0.3	4.3	GO:0031996	thioesterase binding(GO:0031996)
0.2	4.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.2	1.3	GO:0050051	alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.2	3.0	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.2	2.4	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.2	7.9	GO:0030332	cyclin binding(GO:0030332)
0.2	3.3	GO:0016849	phosphorus-oxygen lyase activity(GO:0016849)
0.2	11.6	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.2	5.0	GO:0001848	complement binding(GO:0001848)
0.2	0.6	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.2	36.9	GO:0005057	receptor signaling protein activity(GO:0005057)
0.2	1.9	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	4.6	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1	3.7	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	25.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	0.9	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	1.4	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1	1.5	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	1.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	1.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1	25.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	1.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	2.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	9.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.6	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	10.1	GO:0001618	virus receptor activity(GO:0001618)
0.1	0.9	GO:0004565	beta-galactosidase activity(GO:0004565)
0.1	2.8	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.9	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	2.7	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	0.5	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	2.0	GO:0000339	RNA cap binding(GO:0000339)
0.1	2.0	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	18.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	0.2	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	0.7	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	1.1	GO:0019841	retinol binding(GO:0019841)
0.1	3.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.1	13.6	GO:0008083	growth factor activity(GO:0008083)
0.1	13.7	GO:0019903	protein phosphatase binding(GO:0019903)
0.1	0.6	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1	0.4	GO:0005497	androgen binding(GO:0005497)
0.1	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.5	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.2	GO:0061697	protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.1	3.3	GO:0043621	protein self-association(GO:0043621)
0.0	0.6	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	4.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	10.1	GO:0001047	core promoter binding(GO:0001047)
0.0	1.2	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	1.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	5.3	GO:0000149	SNARE binding(GO:0000149)
0.0	4.4	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	4.0	GO:0004540	ribonuclease activity(GO:0004540)
0.0	6.4	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.0	0.8	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	1.5	GO:0045182	translation regulator activity(GO:0045182)
0.0	5.7	GO:0051015	actin filament binding(GO:0051015)
0.0	4.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.2	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	1.8	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.0	3.4	GO:0031072	heat shock protein binding(GO:0031072)
0.0	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	2.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	14.2	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.5	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.7	GO:0043022	ribosome binding(GO:0043022)
0.0	0.4	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.8	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	55.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.9	36.9	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.7	9.6	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.4	9.8	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	3.6	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.3	13.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.3	12.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.2	10.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.2	11.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	13.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	4.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.2	8.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	4.5	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	23.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	7.5	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	2.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	2.8	PID REELIN PATHWAY	Reelin signaling pathway
0.1	23.3	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	2.5	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	1.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	5.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.1	3.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	1.6	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	18.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	2.3	PID ALK1 PATHWAY	ALK1 signaling events
0.1	2.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	1.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	1.9	NABA COLLAGENS	Genes encoding collagen proteins
0.0	4.5	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	1.9	PID AURORA A PATHWAY	Aurora A signaling
0.0	1.8	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	1.9	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.8	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.7	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.8	PID FANCONI PATHWAY	Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	90.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.8	18.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.7	7.8	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.7	10.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.6	15.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.5	52.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.5	3.9	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.3	8.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.3	5.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.3	3.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.3	9.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	5.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.3	6.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	4.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	19.6	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.2	15.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	8.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2	4.6	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.2	11.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	10.6	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.2	2.5	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	4.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	0.8	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	2.9	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.1	3.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	3.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	17.7	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	7.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	7.5	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	2.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	2.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	2.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	2.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	2.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	2.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	1.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	0.8	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	1.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	4.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.2	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	1.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	2.5	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	2.0	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.7	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	2.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	3.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway