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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PROX1

Z-value: 0.25

Motif logo

Transcription factors associated with PROX1

Gene Symbol Gene ID Gene Info
ENSG00000117707.16 PROX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROX1hg38_v1_chr1_+_213988501_213988549,
hg38_v1_chr1_+_213987929_213987979
0.211.7e-03Click!

Activity profile of PROX1 motif

Sorted Z-values of PROX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PROX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_+_49529869 20.81 ENST00000361446.5
G antigen 12B
chr3_+_52410635 15.26 ENST00000327906.8
PHD finger protein 7
chr2_+_86942118 11.80 ENST00000641458.2
RANBP2 like and GRIP domain containing 1
chr3_+_158571215 10.24 ENST00000498592.6
ENST00000478894.7
myeloid leukemia factor 1
chr4_+_127965394 7.54 ENST00000645843.2
ENST00000388795.9
abhydrolase domain containing 18
chr11_-_72434604 7.02 ENST00000543042.6
caseinolytic mitochondrial matrix peptidase chaperone subunit B
chr15_-_58065703 6.69 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chr13_-_36214521 6.50 ENST00000379881.8
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr2_-_106468326 6.19 ENST00000304514.11
ENST00000409886.4
RANBP2 like and GRIP domain containing 3
chr15_-_58065734 6.02 ENST00000347587.7
aldehyde dehydrogenase 1 family member A2
chr11_-_72434626 5.75 ENST00000646117.1
ENST00000437826.6
caseinolytic mitochondrial matrix peptidase chaperone subunit B
chr3_+_158571153 5.71 ENST00000491767.6
ENST00000618075.4
myeloid leukemia factor 1
chr11_-_72434330 5.44 ENST00000542555.2
ENST00000535990.5
ENST00000294053.9
ENST00000538039.6
ENST00000340729.9
caseinolytic mitochondrial matrix peptidase chaperone subunit B
chr3_+_158571171 5.42 ENST00000484955.5
ENST00000359117.9
ENST00000619577.5
ENST00000471745.5
ENST00000477042.6
ENST00000650753.1
ENST00000651984.1
ENST00000355893.11
ENST00000466246.7
ENST00000469452.5
ENST00000482628.5
myeloid leukemia factor 1
chr7_+_100177897 5.40 ENST00000317296.9
ENST00000615138.5
ENST00000620100.5
ENST00000422690.5
ENST00000439782.1
stromal antigen 3
chr6_+_88047822 5.37 ENST00000237201.2
sperm acrosome associated 1
chr2_-_224569782 5.14 ENST00000409096.5
cullin 3
chr19_+_1354931 5.05 ENST00000591337.7
PWWP domain containing 3A, DNA repair factor
chr5_-_35230332 4.71 ENST00000504500.5
prolactin receptor
chr4_-_120922648 4.67 ENST00000264808.8
PR/SET domain 5
chr20_+_21126074 4.31 ENST00000619189.5
kizuna centrosomal protein
chr20_+_21126037 4.22 ENST00000611685.4
ENST00000616848.4
kizuna centrosomal protein
chr16_+_11976709 4.22 ENST00000566228.6
sorting nexin 29
chr10_+_102714595 4.06 ENST00000602647.5
ENST00000602439.5
ENST00000602764.5
ENST00000369893.10
sideroflexin 2
chr20_+_21125999 4.04 ENST00000620891.4
kizuna centrosomal protein
chr19_+_9178979 4.04 ENST00000642043.1
ENST00000641288.2
olfactory receptor family 7 subfamily D member 2
chr3_+_122564327 4.00 ENST00000296161.9
ENST00000383661.3
deltex E3 ubiquitin ligase 3L
chr20_+_21125981 3.98 ENST00000619574.4
kizuna centrosomal protein
chr1_-_202808464 3.97 ENST00000648469.1
ENST00000648338.1
ENST00000367264.7
ENST00000648473.1
ENST00000648056.1
ENST00000650368.1
lysine demethylase 5B
chr1_-_202808406 3.96 ENST00000650569.1
ENST00000367265.9
ENST00000649770.1
lysine demethylase 5B
chr4_+_127965429 3.91 ENST00000513371.1
ENST00000611882.1
abhydrolase domain containing 18
chr11_+_60842095 3.85 ENST00000227520.10
coiled-coil domain containing 86
chr16_-_11976611 3.75 ENST00000538896.5
ENST00000673243.1
nuclear pore complex interacting protein family member B2
chr2_+_17754116 3.74 ENST00000381254.7
ENST00000524465.5
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr3_-_52770856 3.60 ENST00000461689.5
ENST00000535191.5
ENST00000383721.8
ENST00000233027.10
NIMA related kinase 4
chr7_+_23105747 3.56 ENST00000322275.9
ENST00000339077.10
kelch like family member 7
chr19_-_53103351 3.49 ENST00000599056.5
ENST00000599247.5
ENST00000355147.9
ENST00000683776.1
ENST00000418871.5
ENST00000429604.5
zinc finger protein 160
chr19_-_12156710 3.42 ENST00000455799.1
ENST00000439556.3
zinc finger protein 625
chr6_-_158999748 3.15 ENST00000449822.5
radial spoke head 3
chr16_+_4795357 3.13 ENST00000586005.6
small integral membrane protein 22
chr17_+_16690223 3.07 ENST00000340621.9
ENST00000399273.5
ENST00000456009.4
ENST00000360524.12
coiled-coil domain containing 144A
chr5_-_157142839 2.64 ENST00000286317.6
ENST00000524219.1
mediator complex subunit 7
hepatitis A virus cellular receptor 2
chr6_+_111259474 2.55 ENST00000672554.1
ENST00000673024.1
major facilitator superfamily domain containing 4B
chr3_+_121567924 2.54 ENST00000334384.5
arginine-fifty homeobox
chr19_+_4007714 2.53 ENST00000262971.3
protein inhibitor of activated STAT 4
chr1_+_222644247 2.52 ENST00000340535.11
MIA SH3 domain ER export factor 3
chr4_-_170026333 2.47 ENST00000504999.1
microfibril associated protein 3 like
chr6_+_111259294 2.45 ENST00000672303.1
ENST00000671876.2
ENST00000368847.5
major facilitator superfamily domain containing 4B
chr6_+_37354046 2.44 ENST00000487950.1
ENST00000469731.5
ring finger protein 8
chr12_+_54008961 2.38 ENST00000040584.6
homeobox C8
chr9_+_127397129 2.37 ENST00000610552.4
solute carrier family 2 member 8
chr21_-_33491386 2.36 ENST00000617313.4
ENST00000314399.3
DnaJ heat shock protein family (Hsp40) member C28
chr11_-_62689523 2.29 ENST00000317449.5
LRRN4 C-terminal like
chr17_+_57105899 2.26 ENST00000576295.5
A-kinase anchoring protein 1
chr11_+_61955157 2.24 ENST00000526988.1
bestrophin 1
chr11_-_45286265 2.23 ENST00000020926.8
synaptotagmin 13
chr17_+_28319149 2.23 ENST00000226230.8
ENST00000583381.5
ENST00000582113.1
ENST00000582384.1
transmembrane protein 97
chr12_-_66130702 2.22 ENST00000446587.2
ENST00000266604.7
LLP homolog, long-term synaptic facilitation factor
chr6_-_8102046 2.18 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr12_-_7873027 2.17 ENST00000542782.5
ENST00000396589.6
ENST00000535266.5
ENST00000542505.5
solute carrier family 2 member 14
chr4_-_170026371 2.15 ENST00000361618.4
ENST00000506764.1
microfibril associated protein 3 like
chr10_-_43574555 2.14 ENST00000374446.7
ENST00000535642.5
ENST00000426961.1
zinc finger protein 239
chr11_-_83285965 2.13 ENST00000529073.5
ENST00000529611.5
coiled-coil domain containing 90B
chr1_-_84997079 2.12 ENST00000284027.5
ENST00000370608.8
mucolipin TRP cation channel 2
chr10_-_67696115 2.09 ENST00000433211.7
catenin alpha 3
chr9_+_128504655 2.08 ENST00000683748.1
ENST00000684314.1
ENST00000684331.1
ENST00000684646.1
ENST00000309971.9
ENST00000684139.1
ENST00000372770.4
GLE1 RNA export mediator
chr5_-_132556809 2.02 ENST00000450655.1
interleukin 5
chr7_-_73578558 1.99 ENST00000610724.4
ENST00000305632.11
transducin beta like 2
chr1_-_228416841 1.98 ENST00000366698.7
ENST00000457345.2
tripartite motif containing 17
chr7_+_66629078 1.95 ENST00000449064.6
ENST00000638540.1
ENST00000640234.1
potassium channel tetramerization domain containing 7
chr3_+_196712298 1.88 ENST00000392391.9
ENST00000296333.10
phosphatidylinositol glycan anchor biosynthesis class X
chr1_-_27914717 1.88 ENST00000373909.7
replication protein A2
chr9_-_83956677 1.88 ENST00000376344.8
chromosome 9 open reading frame 64
chr14_+_23372809 1.84 ENST00000397242.2
ENST00000329715.2
interleukin 25
chr6_+_125781108 1.84 ENST00000368357.7
nuclear receptor coactivator 7
chr7_+_66628864 1.82 ENST00000639828.2
ENST00000275532.8
ENST00000640385.1
potassium channel tetramerization domain containing 7
chr11_-_83286328 1.81 ENST00000525503.5
coiled-coil domain containing 90B
chr1_-_27914513 1.75 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
replication protein A2
chr3_-_196287649 1.74 ENST00000441879.5
ENST00000292823.6
ENST00000431016.6
ENST00000411591.5
phosphate cytidylyltransferase 1, choline, alpha
chr7_-_143408848 1.71 ENST00000275815.4
EPH receptor A1
chr1_-_149842736 1.71 ENST00000369159.2
H2A clustered histone 18
chr6_-_89819699 1.68 ENST00000439638.1
ENST00000629399.2
ENST00000369393.8
midasin AAA ATPase 1
chr6_-_46921926 1.65 ENST00000283296.12
adhesion G protein-coupled receptor F5
chr2_-_151973991 1.65 ENST00000534999.6
ENST00000637217.1
ENST00000360283.11
calcium voltage-gated channel auxiliary subunit beta 4
chr6_+_44387686 1.60 ENST00000371477.4
cell division cycle 5 like
chr21_+_34364003 1.59 ENST00000290310.4
potassium voltage-gated channel subfamily E regulatory subunit 2
chr19_-_39032525 1.58 ENST00000509137.6
ENST00000292853.9
F-box protein 27
chr5_-_157142745 1.58 ENST00000420343.1
mediator complex subunit 7
chr7_+_100612102 1.55 ENST00000223054.8
motile sperm domain containing 3
chr19_+_15641280 1.51 ENST00000585846.1
cytochrome P450 family 4 subfamily F member 3
chr1_-_159076742 1.50 ENST00000368130.9
absent in melanoma 2
chrX_-_52517213 1.50 ENST00000375616.5
X antigen family member 1B
chr7_+_100612372 1.45 ENST00000493970.5
motile sperm domain containing 3
chr10_+_14878848 1.45 ENST00000433779.5
ENST00000378325.7
ENST00000354919.11
ENST00000313519.9
ENST00000420416.1
suppressor of variegation 3-9 homolog 2
chr7_+_100612522 1.45 ENST00000393950.7
ENST00000424091.2
motile sperm domain containing 3
chr16_-_31074193 1.44 ENST00000300849.5
zinc finger protein 668
chr19_+_52570268 1.43 ENST00000596514.5
ENST00000391785.8
ENST00000301093.6
zinc finger protein 701
chr7_+_100612430 1.43 ENST00000379527.6
motile sperm domain containing 3
chr17_+_4807119 1.43 ENST00000263088.11
ENST00000572940.5
phospholipase D2
chr5_-_22853320 1.42 ENST00000504376.6
ENST00000382254.6
cadherin 12
chr11_-_59615673 1.41 ENST00000263847.6
oxysterol binding protein
chr13_+_43023577 1.40 ENST00000379221.4
DnaJ heat shock protein family (Hsp40) member C15
chr1_-_211133945 1.39 ENST00000640044.1
ENST00000640566.1
potassium voltage-gated channel subfamily H member 1
chr19_-_45406327 1.36 ENST00000593226.5
ENST00000418234.6
protein phosphatase 1 regulatory subunit 13 like
chr11_+_28110275 1.33 ENST00000303459.10
ENST00000634762.1
ENST00000634721.1
methyltransferase like 15
chr7_+_66629023 1.33 ENST00000639879.1
ENST00000640851.1
potassium channel tetramerization domain containing 7
chr5_+_180988840 1.30 ENST00000342868.7
butyrophilin like 3
chr7_-_91880672 1.30 ENST00000456229.1
ENST00000442961.1
ENST00000406735.6
ENST00000419292.1
ENST00000351870.8
mitochondrial transcription termination factor 1
chr4_+_127965267 1.27 ENST00000398965.5
abhydrolase domain containing 18
chrX_+_102307022 1.27 ENST00000604790.2
nuclear RNA export factor 2
chr3_-_129893551 1.24 ENST00000505616.5
ENST00000426664.6
ENST00000648771.1
ENST00000393238.8
transmembrane and coiled-coil domain family 1
chr15_+_84980440 1.23 ENST00000310298.8
ENST00000557957.5
phosphodiesterase 8A
chr4_+_127965361 1.18 ENST00000444616.5
abhydrolase domain containing 18
chr11_-_30016945 1.18 ENST00000328224.7
potassium voltage-gated channel subfamily A member 4
chrX_-_120561424 1.17 ENST00000681206.1
ENST00000679927.1
ENST00000336592.11
cullin 4B
chr4_-_170027209 1.16 ENST00000393702.7
microfibril associated protein 3 like
chrX_+_153179276 1.15 ENST00000356661.7
MAGE family member A1
chr12_+_52274610 1.15 ENST00000423955.7
keratin 86
chr1_+_70411180 1.12 ENST00000411986.6
cystathionine gamma-lyase
chr1_-_202808432 1.11 ENST00000649200.1
ENST00000650493.1
lysine demethylase 5B
chr15_-_31161157 1.10 ENST00000542188.5
transient receptor potential cation channel subfamily M member 1
chr16_-_14694308 1.10 ENST00000438167.8
phospholipase A2 group X
chr16_+_31873772 1.09 ENST00000394846.7
ENST00000300870.15
zinc finger protein 267
chr3_-_197298092 1.08 ENST00000392382.6
discs large MAGUK scaffold protein 1
chr11_-_74170792 1.08 ENST00000680231.1
ENST00000681143.1
ENST00000679906.1
ENST00000681310.1
ENST00000414160.7
ENST00000538361.2
C2 domain containing 3 centriole elongation regulator
chr1_+_35079374 1.07 ENST00000359858.9
ENST00000373330.1
zinc finger MYM-type containing 1
chr12_-_11269805 1.05 ENST00000538488.2
proline rich protein BstNI subfamily 3
chr19_-_16472003 1.05 ENST00000248070.10
ENST00000594975.5
epidermal growth factor receptor pathway substrate 15 like 1
chr2_-_53859929 1.04 ENST00000394705.3
ENST00000406625.6
G protein-coupled receptor 75
ankyrin repeat and SOCS box containing 3
chr16_-_66552460 1.01 ENST00000678015.1
ENST00000569718.6
ENST00000678314.1
ENST00000562484.2
thymidine kinase 2
chr5_+_50665899 1.00 ENST00000505697.6
poly(ADP-ribose) polymerase family member 8
chr3_-_131026726 0.97 ENST00000514044.5
ENST00000264992.8
asteroid homolog 1
chr19_-_44304968 0.96 ENST00000591609.1
ENST00000589799.5
ENST00000291182.9
ENST00000650576.1
ENST00000589248.5
zinc finger protein 235
chr11_+_1838970 0.95 ENST00000381911.6
troponin I2, fast skeletal type
chr19_+_11814256 0.94 ENST00000304060.10
ENST00000457526.1
ENST00000427505.5
zinc finger protein 440
chr19_+_45406630 0.94 ENST00000309424.8
RNA polymerase I subunit G
chr5_+_132556911 0.92 ENST00000651541.1
ENST00000378823.8
ENST00000652485.1
RAD50 double strand break repair protein
chr5_-_178996184 0.92 ENST00000650031.1
glutamate metabotropic receptor 6
chr7_-_102517755 0.91 ENST00000306682.6
ENST00000465829.6
ENST00000541662.5
RAS p21 protein activator 4B
chr11_-_74170975 0.89 ENST00000539061.6
ENST00000680645.1
ENST00000334126.12
ENST00000680718.1
C2 domain containing 3 centriole elongation regulator
chr5_-_157575767 0.89 ENST00000257527.9
ADAM metallopeptidase domain 19
chr7_-_102616692 0.89 ENST00000521076.5
ENST00000462172.5
ENST00000522801.5
ENST00000262940.12
ENST00000449970.6
RAS p21 protein activator 4
chr1_-_211134135 0.89 ENST00000638983.1
ENST00000271751.10
ENST00000639952.1
novel protein
potassium voltage-gated channel subfamily H member 1
chr10_-_121598234 0.86 ENST00000369058.7
ENST00000369060.8
ENST00000359354.6
fibroblast growth factor receptor 2
chr10_+_102245371 0.85 ENST00000676513.1
ENST00000676939.1
ENST00000677947.1
ENST00000677247.1
ENST00000369983.4
ENST00000678351.1
ENST00000679238.1
ENST00000677439.1
ENST00000677240.1
ENST00000677618.1
ENST00000673650.1
ENST00000674034.1
ENST00000676993.1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr1_+_241532370 0.85 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr12_+_63779894 0.84 ENST00000261234.11
ribitol xylosyltransferase 1
chr1_+_6579986 0.80 ENST00000377674.9
ENST00000319084.9
ENST00000435905.5
zinc finger and BTB domain containing 48
chr4_-_165279679 0.80 ENST00000505354.2
glycerol kinase 3 pseudogene
chr15_+_43517590 0.79 ENST00000300231.6
microtubule associated protein 1A
chrX_+_71366290 0.79 ENST00000683782.1
ENST00000423759.6
TATA-box binding protein associated factor 1
chr13_+_49247905 0.76 ENST00000251108.10
ENST00000429346.1
cytidine and dCMP deaminase domain containing 1
chrX_+_152714586 0.76 ENST00000331220.6
ENST00000370293.6
ENST00000423993.5
ENST00000447530.5
ENST00000682532.1
ENST00000458057.5
ENST00000422085.5
ENST00000453150.5
ENST00000409560.1
MAGE family member A2B
chr1_+_207496229 0.76 ENST00000367051.6
ENST00000367053.6
ENST00000367052.6
complement C3b/C4b receptor 1 (Knops blood group)
chr5_-_157575741 0.75 ENST00000517905.1
ADAM metallopeptidase domain 19
chr1_+_207053229 0.75 ENST00000367080.8
ENST00000367079.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr4_+_150582119 0.74 ENST00000317605.6
mab-21 like 2
chr3_+_138347648 0.73 ENST00000614350.4
ENST00000289104.8
muscle RAS oncogene homolog
chr3_+_152835122 0.73 ENST00000305097.6
purinergic receptor P2Y1
chrX_-_152753840 0.73 ENST00000617505.1
ENST00000684311.1
ENST00000617846.4
ENST00000595583.5
ENST00000620710.4
ENST00000611557.4
ENST00000623806.3
ENST00000623438.3
ENST00000598543.5
ENST00000611674.4
MAGE family member A2
chr19_+_53395125 0.71 ENST00000396408.8
ENST00000505866.1
ENST00000594030.2
zinc finger protein 765
chr8_+_143990047 0.70 ENST00000395068.9
ENST00000313269.5
glutamate ionotropic receptor NMDA type subunit associated protein 1
chr12_+_63780126 0.69 ENST00000537373.5
ribitol xylosyltransferase 1
chr1_-_173207322 0.69 ENST00000281834.4
TNF superfamily member 4
chr3_-_49903863 0.68 ENST00000296474.8
ENST00000621387.4
macrophage stimulating 1 receptor
chr2_-_162152239 0.67 ENST00000418842.7
glucagon
chr1_+_154993581 0.67 ENST00000392487.1
lens epithelial protein
chr13_+_26557659 0.67 ENST00000335327.6
ENST00000361042.8
ENST00000671038.1
WASP family member 3
chr2_+_96335752 0.67 ENST00000240423.9
ENST00000427946.5
ENST00000435975.5
ENST00000456906.5
ENST00000455200.5
non-SMC condensin I complex subunit H
chr7_+_151048526 0.65 ENST00000349064.10
acid sensing ion channel subunit 3
chr8_-_86743626 0.64 ENST00000320005.6
cyclic nucleotide gated channel subunit beta 3
chr10_+_43138435 0.64 ENST00000374466.4
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr17_-_50468871 0.63 ENST00000508540.6
ENST00000258969.4
chondroadherin
chr6_+_37353972 0.63 ENST00000373479.9
ring finger protein 8
chr22_+_17638584 0.63 ENST00000337612.9
ENST00000418951.6
ENST00000538149.5
ENST00000543133.5
ENST00000611738.4
ENST00000616863.4
ENST00000618481.4
ENST00000317582.10
ENST00000493680.5
BCL2 like 13
chr1_+_179293760 0.57 ENST00000367619.8
sterol O-acyltransferase 1
chr18_+_32190015 0.57 ENST00000581447.1
meprin A subunit beta
chr1_+_179293714 0.56 ENST00000540564.5
ENST00000539888.5
sterol O-acyltransferase 1
chr21_-_25607474 0.56 ENST00000352957.9
ENST00000419219.1
ENST00000307301.11
mitochondrial ribosomal protein L39
chr10_+_30434176 0.55 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr22_+_17638796 0.54 ENST00000355028.4
BCL2 like 13
chr12_+_49346885 0.54 ENST00000549441.7
DnaJ heat shock protein family (Hsp40) member C22
chr22_+_45163910 0.53 ENST00000347635.9
ENST00000407019.6
ENST00000424634.5
ENST00000417702.5
ENST00000430547.5
nucleoporin 50
chr3_+_138348570 0.52 ENST00000423968.7
muscle RAS oncogene homolog
chr18_+_32190033 0.51 ENST00000269202.11
meprin A subunit beta
chr1_-_160862880 0.51 ENST00000368034.9
CD244 molecule
chr12_-_121858849 0.50 ENST00000289004.8
4-hydroxyphenylpyruvate dioxygenase
chr1_+_6624842 0.50 ENST00000054650.8
THAP domain containing 3
chr1_-_207052980 0.49 ENST00000367084.1
YOD1 deubiquitinase
chrX_+_118727575 0.48 ENST00000371642.1
ENST00000371666.8
interleukin 13 receptor subunit alpha 1
chr2_-_151973780 0.47 ENST00000637514.1
ENST00000636350.1
ENST00000434468.2
ENST00000637762.1
ENST00000637779.1
ENST00000637547.1
ENST00000636901.1
ENST00000397327.7
ENST00000636721.1
ENST00000636380.1
ENST00000637284.1
ENST00000636617.1
ENST00000636947.1
ENST00000638091.1
ENST00000636108.1
ENST00000638040.1
ENST00000636773.1
ENST00000637418.1
ENST00000637216.1
calcium voltage-gated channel auxiliary subunit beta 4
chr8_-_33599935 0.45 ENST00000523956.1
ENST00000256261.9
dual specificity phosphatase 26
chr19_+_54738503 0.44 ENST00000342376.4
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
chr3_+_12484540 0.42 ENST00000680943.1
ENST00000680421.1
ENST00000679367.1
ENST00000679876.1
ENST00000444864.6
ENST00000680986.1
tRNA splicing endonuclease subunit 2
chrX_-_153971810 0.40 ENST00000310441.12
host cell factor C1
chr19_-_15418979 0.40 ENST00000397410.10
ENST00000596195.5
ENST00000595067.1
ENST00000595465.6
ENST00000680649.1
ENST00000679638.1
ENST00000600247.5
A-kinase anchoring protein 8 like
chr7_+_91940970 0.40 ENST00000359028.7
A-kinase anchoring protein 9
chr12_+_49346911 0.39 ENST00000395069.3
DnaJ heat shock protein family (Hsp40) member C22
chr10_+_45374235 0.37 ENST00000612635.4
arachidonate 5-lipoxygenase
chr3_+_138348592 0.36 ENST00000621127.4
ENST00000494949.5
muscle RAS oncogene homolog

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 21.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.8 9.0 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
1.7 5.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
1.4 12.7 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.2 3.7 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.1 5.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.9 4.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.9 2.6 GO:2000521 tolerance induction dependent upon immune response(GO:0002461) negative regulation of immunological synapse formation(GO:2000521)
0.8 2.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.7 2.0 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.6 18.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.5 2.5 GO:0009624 response to nematode(GO:0009624)
0.4 3.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 1.6 GO:1990637 response to prolactin(GO:1990637)
0.4 1.6 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.4 2.0 GO:0021997 neural plate axis specification(GO:0021997)
0.4 2.5 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 9.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.3 5.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 0.9 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.3 1.5 GO:0070269 pyroptosis(GO:0070269)
0.3 1.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 2.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.3 1.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 2.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.3 1.5 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.2 3.6 GO:0001302 replicative cell aging(GO:0001302)
0.2 1.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2 1.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 0.7 GO:0019046 release from viral latency(GO:0019046)
0.2 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 0.6 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 1.5 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.2 1.4 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.2 2.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 0.8 GO:0036369 transcription factor catabolic process(GO:0036369)
0.2 2.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 0.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 0.5 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.2 1.0 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.2 0.5 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.2 0.8 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 2.1 GO:0006449 regulation of translational termination(GO:0006449)
0.2 1.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 3.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 2.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.5 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 1.7 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 1.3 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 5.2 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 0.9 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.7 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891) sensory perception of sour taste(GO:0050915)
0.1 4.7 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.1 1.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.4 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 1.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 18.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 2.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.7 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 6.5 GO:0048477 oogenesis(GO:0048477)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.4 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.1 2.2 GO:0097484 dendrite extension(GO:0097484)
0.1 0.3 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 2.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.4 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 1.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.7 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 3.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.7 GO:1901984 negative regulation of protein acetylation(GO:1901984)
0.0 1.2 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.3 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.4 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 1.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 1.9 GO:0006400 tRNA modification(GO:0006400)
0.0 7.1 GO:0007051 spindle organization(GO:0007051)
0.0 1.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.7 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 2.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 1.3 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 1.0 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 1.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 6.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.6 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.9 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.1 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 1.2 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.8 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.6 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.1 GO:0070268 cornification(GO:0070268)
0.0 1.4 GO:0034332 adherens junction organization(GO:0034332)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.6 GO:0030893 meiotic cohesin complex(GO:0030893)
0.6 5.1 GO:0005827 polar microtubule(GO:0005827)
0.5 2.0 GO:0035841 new growing cell tip(GO:0035841)
0.4 2.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 1.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.3 1.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.3 2.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.3 5.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 0.7 GO:0000799 nuclear condensin complex(GO:0000799)
0.2 5.4 GO:0002080 acrosomal membrane(GO:0002080)
0.2 2.4 GO:0017119 Golgi transport complex(GO:0017119)
0.2 1.7 GO:0042587 glycogen granule(GO:0042587)
0.1 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 4.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 4.2 GO:0016592 mediator complex(GO:0016592)
0.1 0.4 GO:0044307 dendritic branch(GO:0044307)
0.1 1.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 2.1 GO:0005916 fascia adherens(GO:0005916)
0.1 4.7 GO:0031904 endosome lumen(GO:0031904)
0.1 3.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.0 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 5.0 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 11.1 GO:0016607 nuclear speck(GO:0016607)
0.0 2.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 2.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.6 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 9.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
1.7 5.1 GO:0031208 POZ domain binding(GO:0031208)
1.2 4.7 GO:0004925 prolactin receptor activity(GO:0004925)
1.1 12.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.9 5.4 GO:0003796 lysozyme activity(GO:0003796)
0.7 2.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.6 2.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.5 3.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.5 2.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.5 1.5 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.5 1.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.4 2.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.4 1.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 1.1 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.3 1.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 1.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3 9.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.3 2.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 0.9 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.3 2.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 4.6 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.2 1.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.2 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.7 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.2 0.8 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 0.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.2 0.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2 0.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 0.8 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 2.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.0 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 1.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.9 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 0.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 3.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.6 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 1.6 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 1.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.7 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) adenosine receptor binding(GO:0031685)
0.1 1.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.9 GO:0031014 troponin T binding(GO:0031014)
0.1 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 3.6 GO:0030145 manganese ion binding(GO:0030145)
0.1 1.2 GO:0030955 potassium ion binding(GO:0030955)
0.1 0.8 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 1.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 2.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 8.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 3.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 20.2 GO:0016887 ATPase activity(GO:0016887)
0.0 2.2 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 7.1 GO:0042393 histone binding(GO:0042393)
0.0 5.8 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 3.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.1 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 11.1 GO:0019901 protein kinase binding(GO:0019901)
0.0 2.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 13.2 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 2.0 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 3.3 PID ATM PATHWAY ATM pathway
0.1 4.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 2.0 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.9 PID ARF 3PATHWAY Arf1 pathway
0.1 2.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 3.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 5.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 3.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 4.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 4.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 1.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 6.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis