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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for RBPJ

Z-value: 1.91

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Transcription factors associated with RBPJ

Gene Symbol Gene ID Gene Info
RBPJ
ENSG00000168214.21 RBPJ

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RBPJhg38_v1_chr4_+_26320563_26320665,
hg38_v1_chr4_+_26321365_26321410		-0.091.7e-01Click!

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_-_79767843 11.77 ENST00000337919.9
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr17_-_58529277 11.41 ENST00000579371.5
SEPTIN4
septin 4
chr17_-_58529344 11.38 ENST00000317268.7
SEPTIN4
septin 4
chr17_-_58529303 11.13 ENST00000580844.5
SEPTIN4
septin 4
chr8_-_79767462 10.46 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr4_-_175812746 9.02 ENST00000393658.6
GPM6A
glycoprotein M6A
chr4_+_155667654 8.86 ENST00000513574.1
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
chr9_-_137028878 8.42 ENST00000625103.1
ENST00000614293.4
ABCA2
ATP binding cassette subfamily A member 2
chr12_+_12785652 8.02 ENST00000356591.5
APOLD1
apolipoprotein L domain containing 1
chr12_-_16606795 7.63 ENST00000447609.5
LMO3
LIM domain only 3
chr3_+_142723999 7.59 ENST00000476941.6
ENST00000273482.10
TRPC1
transient receptor potential cation channel subfamily C member 1
chr8_-_22232020 7.28 ENST00000454243.7
ENST00000321613.7
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr16_-_70685975 7.22 ENST00000338779.11
MTSS2
MTSS I-BAR domain containing 2
chr10_-_37857582 6.92 ENST00000395867.8
ENST00000611278.4
ZNF248
zinc finger protein 248
chr4_-_86594037 6.91 ENST00000641050.1
ENST00000641831.1
ENST00000515400.3
ENST00000641391.1
ENST00000641157.1
ENST00000641737.1
ENST00000502302.6
ENST00000640527.1
ENST00000512046.2
ENST00000513186.7
MAPK10
mitogen-activated protein kinase 10
chr4_+_155667198 6.77 ENST00000296518.11
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
chr19_+_50203607 6.60 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
MYH14
myosin heavy chain 14
chr10_-_37858037 6.06 ENST00000395873.7
ENST00000357328.8
ENST00000395874.2
ZNF248
zinc finger protein 248
chr6_+_30884353 6.02 ENST00000428153.6
ENST00000376568.8
ENST00000452441.5
ENST00000515219.5
DDR1
discoidin domain receptor tyrosine kinase 1
chr20_-_49278416 5.89 ENST00000371754.8
ZNFX1
zinc finger NFX1-type containing 1
chr4_+_155667096 5.73 ENST00000393832.7
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
chr4_-_73069696 5.71 ENST00000507544.3
ENST00000295890.8
COX18
cytochrome c oxidase assembly factor COX18
chr17_-_35930727 5.29 ENST00000616596.4
ENST00000612980.4
ENST00000613308.4
ENST00000619876.4
RDM1
RAD52 motif containing 1
chr19_-_38899800 5.28 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
SIRT2
sirtuin 2
chr5_-_140564245 5.23 ENST00000412920.7
ENST00000511201.2
ENST00000354402.9
ENST00000356738.6
APBB3
amyloid beta precursor protein binding family B member 3
chr6_+_30884063 4.99 ENST00000511510.5
ENST00000376569.7
ENST00000376570.8
ENST00000504927.5
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_+_2796404 4.98 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr8_-_126557691 4.86 ENST00000652209.1
LRATD2
LRAT domain containing 2
chr1_-_223363337 4.78 ENST00000608996.5
SUSD4
sushi domain containing 4
chr2_+_218959635 4.72 ENST00000302625.6
CDK5R2
cyclin dependent kinase 5 regulatory subunit 2
chr3_+_159852933 4.61 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr1_+_14945775 4.52 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr20_+_44582549 4.52 ENST00000372886.6
PKIG
cAMP-dependent protein kinase inhibitor gamma
chr11_+_112961480 4.44 ENST00000621850.4
NCAM1
neural cell adhesion molecule 1
chr14_-_52791597 4.39 ENST00000216410.8
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr19_-_38899529 4.34 ENST00000249396.12
ENST00000437828.5
SIRT2
sirtuin 2
chr19_-_42242526 4.31 ENST00000222330.8
ENST00000676537.1
GSK3A
glycogen synthase kinase 3 alpha
chr20_-_46308485 4.30 ENST00000537909.4
CDH22
cadherin 22
chr11_+_112961402 4.25 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
NCAM1
neural cell adhesion molecule 1
chr16_+_1612337 4.24 ENST00000674071.1
ENST00000397412.8
CRAMP1
cramped chromatin regulator homolog 1
chr1_-_223364059 4.24 ENST00000343846.7
ENST00000484758.6
ENST00000344029.6
ENST00000366878.9
ENST00000494793.6
ENST00000681285.1
ENST00000680429.1
ENST00000681669.1
ENST00000681305.1
SUSD4
sushi domain containing 4
chr16_-_30091226 4.17 ENST00000279386.6
ENST00000627355.2
TBX6
T-box transcription factor 6
chr6_+_42564060 4.11 ENST00000372903.6
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_+_36224410 4.09 ENST00000469141.6
ENST00000648638.1
ENST00000354618.10
THRAP3
thyroid hormone receptor associated protein 3
chr11_+_112961247 3.99 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
NCAM1
neural cell adhesion molecule 1
chr11_-_31817904 3.96 ENST00000423822.7
PAX6
paired box 6
chr11_-_31817937 3.92 ENST00000638965.1
ENST00000241001.13
ENST00000638914.3
ENST00000379132.8
ENST00000379129.7
PAX6
paired box 6
chr19_-_45792755 3.91 ENST00000377735.7
ENST00000270223.7
DMWD
DM1 locus, WD repeat containing
chr19_-_55179390 3.77 ENST00000590851.5
SYT5
synaptotagmin 5
chr16_-_1611985 3.63 ENST00000426508.7
IFT140
intraflagellar transport 140
chr14_-_52791462 3.60 ENST00000650397.1
ENST00000554230.5
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr11_+_66744618 3.60 ENST00000524551.5
ENST00000525908.6
ENST00000540737.7
ENST00000527634.5
C11orf80
chromosome 11 open reading frame 80
chrX_-_153971169 3.53 ENST00000369984.4
HCFC1
host cell factor C1
chr10_-_97445850 3.51 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
EXOSC1
exosome component 1
chr1_+_50106265 3.40 ENST00000357083.8
ELAVL4
ELAV like RNA binding protein 4
chr12_-_48865863 3.34 ENST00000309739.6
RND1
Rho family GTPase 1
chr21_+_6499203 3.32 ENST00000619537.5
CRYAA2
crystallin alpha A2
chr10_+_116545907 3.32 ENST00000369221.2
PNLIP
pancreatic lipase
chr7_-_120858066 3.16 ENST00000222747.8
TSPAN12
tetraspanin 12
chr21_-_31558977 3.12 ENST00000286827.7
ENST00000541036.5
TIAM1
TIAM Rac1 associated GEF 1
chr5_-_116536458 3.05 ENST00000510263.5
SEMA6A
semaphorin 6A
chr11_+_66744831 2.99 ENST00000642265.1
ENST00000532565.6
C11orf80
chromosome 11 open reading frame 80
chr7_+_74209947 2.91 ENST00000475494.5
ENST00000398475.5
LAT2
linker for activation of T cells family member 2
chrX_+_16123544 2.88 ENST00000380289.3
GRPR
gastrin releasing peptide receptor
chr16_-_10182394 2.84 ENST00000330684.4
GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
chrX_+_123859807 2.82 ENST00000434753.7
ENST00000430625.1
XIAP
X-linked inhibitor of apoptosis
chr10_+_111077021 2.81 ENST00000280155.4
ADRA2A
adrenoceptor alpha 2A
chr10_+_73168111 2.79 ENST00000242505.11
FAM149B1
family with sequence similarity 149 member B1
chr11_-_32430811 2.77 ENST00000379079.8
ENST00000530998.5
WT1
WT1 transcription factor
chr9_-_127950716 2.70 ENST00000373084.8
FAM102A
family with sequence similarity 102 member A
chr13_-_24922788 2.66 ENST00000381884.9
CENPJ
centromere protein J
chr11_+_118607598 2.66 ENST00000600882.6
ENST00000356063.9
PHLDB1
pleckstrin homology like domain family B member 1
chr9_+_99821876 2.62 ENST00000395097.7
NR4A3
nuclear receptor subfamily 4 group A member 3
chr14_-_21526312 2.54 ENST00000537235.2
SALL2
spalt like transcription factor 2
chr3_-_184017863 2.54 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ABCC5
ATP binding cassette subfamily C member 5
chr19_-_36379185 2.51 ENST00000270001.12
ZFP14
ZFP14 zinc finger protein
chr5_+_178941186 2.51 ENST00000320129.7
ENST00000519564.2
ZNF454
zinc finger protein 454
chr16_-_10182754 2.50 ENST00000396573.6
ENST00000675398.1
GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
chr3_+_156142962 2.48 ENST00000471742.5
KCNAB1
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chrX_+_123859976 2.41 ENST00000371199.8
XIAP
X-linked inhibitor of apoptosis
chr4_+_70195719 2.36 ENST00000683306.1
ODAM
odontogenic, ameloblast associated
chr6_+_125749623 2.34 ENST00000368364.4
HEY2
hes related family bHLH transcription factor with YRPW motif 2
chr10_+_122560679 2.27 ENST00000657942.1
DMBT1
deleted in malignant brain tumors 1
chr17_-_16215520 2.21 ENST00000582357.5
ENST00000436828.5
ENST00000268712.8
ENST00000411510.5
ENST00000395857.7
NCOR1
nuclear receptor corepressor 1
chr10_+_122560639 2.18 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
DMBT1
deleted in malignant brain tumors 1
chr17_+_31094880 2.18 ENST00000487476.5
ENST00000356175.7
NF1
neurofibromin 1
chr19_+_39997031 2.11 ENST00000599504.5
ENST00000596894.5
ENST00000601138.5
ENST00000347077.9
ENST00000600094.5
ZNF546
zinc finger protein 546
chr15_-_33194696 2.06 ENST00000320930.7
ENST00000616417.5
FMN1
formin 1
chr14_-_92748570 2.05 ENST00000553918.1
ENST00000555699.5
ENST00000334869.9
ENST00000553802.5
ENST00000554397.5
ENST00000554919.5
ENST00000554080.5
ENST00000553371.1
ENST00000557434.5
ENST00000393218.6
LGMN
legumain
chr7_+_90709816 2.04 ENST00000436577.3
CDK14
cyclin dependent kinase 14
chr3_+_169773384 2.00 ENST00000349841.10
ENST00000356716.8
MYNN
myoneurin
chr7_+_94394886 1.96 ENST00000297268.11
ENST00000620463.1
COL1A2
collagen type I alpha 2 chain
chr10_+_122560751 1.86 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
DMBT1
deleted in malignant brain tumors 1
chr7_+_90709530 1.85 ENST00000406263.5
CDK14
cyclin dependent kinase 14
chr19_+_3094348 1.82 ENST00000078429.9
GNA11
G protein subunit alpha 11
chr3_+_46407558 1.81 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
C-C motif chemokine receptor like 2
chr1_+_43389889 1.68 ENST00000562955.2
ENST00000634258.3
SZT2
SZT2 subunit of KICSTOR complex
chr9_+_99821846 1.61 ENST00000338488.8
ENST00000618101.4
NR4A3
nuclear receptor subfamily 4 group A member 3
chr1_-_147172456 1.61 ENST00000254101.4
PRKAB2
protein kinase AMP-activated non-catalytic subunit beta 2
chr2_+_48568981 1.60 ENST00000394754.5
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr5_+_141412979 1.60 ENST00000612503.1
ENST00000398610.3
PCDHGA10
protocadherin gamma subfamily A, 10
chr2_+_3595049 1.59 ENST00000236693.11
ENST00000349077.9
COLEC11
collectin subfamily member 11
chr9_-_95507416 1.54 ENST00000429896.6
PTCH1
patched 1
chr7_+_90709231 1.52 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr1_-_151008365 1.46 ENST00000361936.9
ENST00000361738.11
MINDY1
MINDY lysine 48 deubiquitinase 1
chr2_-_79087986 1.46 ENST00000305089.8
REG1B
regenerating family member 1 beta
chr3_+_171843337 1.44 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
TMEM212
transmembrane protein 212
chr6_-_32224060 1.40 ENST00000375023.3
NOTCH4
notch receptor 4
chr5_+_178895892 1.39 ENST00000520660.5
ENST00000361362.7
ENST00000520805.5
ZFP2
ZFP2 zinc finger protein
chr12_+_57772587 1.37 ENST00000300209.13
EEF1AKMT3
EEF1A lysine methyltransferase 3
chr18_+_13218195 1.32 ENST00000679167.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr9_-_14722725 1.30 ENST00000380911.4
CER1
cerberus 1, DAN family BMP antagonist
chr17_+_31094969 1.30 ENST00000431387.8
ENST00000358273.9
NF1
neurofibromin 1
chr3_-_45915698 1.27 ENST00000539217.5
LZTFL1
leucine zipper transcription factor like 1
chr21_-_30166782 1.27 ENST00000286808.5
CLDN17
claudin 17
chr14_-_52950992 1.26 ENST00000343279.8
ENST00000399304.7
ENST00000395631.6
ENST00000341590.8
FERMT2
fermitin family member 2
chr16_+_53703963 1.25 ENST00000636218.1
ENST00000637001.1
ENST00000471389.6
ENST00000637969.1
ENST00000640179.1
FTO
FTO alpha-ketoglutarate dependent dioxygenase
chr12_-_89656093 1.23 ENST00000359142.7
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr12_-_89656051 1.23 ENST00000261173.6
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr2_-_144516154 1.19 ENST00000637304.1
ZEB2
zinc finger E-box binding homeobox 2
chrX_-_119605870 1.16 ENST00000542113.3
NKRF
NFKB repressing factor
chr12_+_6200759 1.16 ENST00000645565.1
ENST00000382515.7
CD9
CD9 molecule
chr8_+_106726012 1.13 ENST00000449762.6
ENST00000297447.10
OXR1
oxidation resistance 1
chr9_+_706841 1.13 ENST00000382293.7
KANK1
KN motif and ankyrin repeat domains 1
chr16_-_70685791 1.11 ENST00000616026.4
MTSS2
MTSS I-BAR domain containing 2
chr19_+_50025714 1.10 ENST00000598809.5
ENST00000595661.5
ENST00000391821.6
ZNF473
zinc finger protein 473
chr20_+_31475278 1.04 ENST00000201979.3
REM1
RRAD and GEM like GTPase 1
chrX_-_70260199 1.03 ENST00000374519.4
P2RY4
pyrimidinergic receptor P2Y4
chr10_-_95441015 1.01 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
SORBS1
sorbin and SH3 domain containing 1
chr19_+_38899946 1.01 ENST00000572515.5
ENST00000313582.6
ENST00000575359.5
NFKBIB
NFKB inhibitor beta
chr16_-_53703883 1.00 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1L
RPGRIP1 like
chr22_+_39901075 0.97 ENST00000344138.9
GRAP2
GRB2 related adaptor protein 2
chr2_-_144516397 0.96 ENST00000638128.1
ZEB2
zinc finger E-box binding homeobox 2
chr5_-_138178599 0.94 ENST00000454473.5
ENST00000418329.5
ENST00000254900.10
ENST00000230901.9
ENST00000402931.5
ENST00000411594.6
ENST00000430331.1
BRD8
bromodomain containing 8
chr4_-_119628007 0.94 ENST00000420633.1
ENST00000394439.5
PDE5A
phosphodiesterase 5A
chr3_+_194136138 0.93 ENST00000232424.4
HES1
hes family bHLH transcription factor 1
chr17_-_41624541 0.93 ENST00000540235.5
ENST00000311208.13
KRT17
keratin 17
chr5_-_88877967 0.93 ENST00000508610.5
ENST00000636294.1
MEF2C
myocyte enhancer factor 2C
chrX_-_49264668 0.85 ENST00000455775.7
ENST00000652559.1
ENST00000376207.10
ENST00000557224.6
ENST00000684155.1
ENST00000376199.7
FOXP3
forkhead box P3
chr1_-_7940825 0.84 ENST00000377507.8
TNFRSF9
TNF receptor superfamily member 9
chr1_-_92486049 0.83 ENST00000427103.5
GFI1
growth factor independent 1 transcriptional repressor
chr16_-_53703810 0.83 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1L
RPGRIP1 like
chrX_+_19343893 0.82 ENST00000540249.5
ENST00000545074.5
ENST00000379806.9
ENST00000423505.5
ENST00000422285.7
ENST00000417819.5
ENST00000355808.9
ENST00000379805.3
PDHA1
pyruvate dehydrogenase E1 subunit alpha 1
chr6_-_75493629 0.80 ENST00000393004.6
FILIP1
filamin A interacting protein 1
chr11_+_118607579 0.78 ENST00000530708.4
PHLDB1
pleckstrin homology like domain family B member 1
chr4_+_26319636 0.77 ENST00000342295.6
ENST00000506956.5
ENST00000512671.6
ENST00000345843.8
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chrX_+_147911910 0.77 ENST00000370475.9
FMR1
FMRP translational regulator 1
chr16_+_23302292 0.73 ENST00000343070.7
SCNN1B
sodium channel epithelial 1 subunit beta
chr11_-_8938211 0.66 ENST00000531618.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr3_-_87276577 0.63 ENST00000344265.8
ENST00000350375.7
POU1F1
POU class 1 homeobox 1
chr1_-_39639626 0.61 ENST00000372852.4
HEYL
hes related family bHLH transcription factor with YRPW motif like
chr15_+_40405787 0.58 ENST00000610693.5
ENST00000479013.7
ENST00000487418.8
IVD
isovaleryl-CoA dehydrogenase
chr1_+_174799895 0.56 ENST00000489615.5
RABGAP1L
RAB GTPase activating protein 1 like
chr3_+_69763549 0.56 ENST00000472437.5
MITF
melanocyte inducing transcription factor
chrX_+_147911943 0.55 ENST00000621453.4
ENST00000218200.12
ENST00000370471.7
ENST00000440235.6
ENST00000370477.5
ENST00000621987.4
FMR1
FMRP translational regulator 1
chr20_+_2652622 0.54 ENST00000329276.10
ENST00000445139.1
NOP56
NOP56 ribonucleoprotein
chr11_-_124935973 0.53 ENST00000298251.5
HEPACAM
hepatic and glial cell adhesion molecule
chr5_+_132673983 0.52 ENST00000622422.1
ENST00000231449.7
ENST00000350025.2
IL4
interleukin 4
chr12_-_4649043 0.50 ENST00000545990.6
ENST00000228850.6
AKAP3
A-kinase anchoring protein 3
chr7_-_16465728 0.50 ENST00000307068.5
SOSTDC1
sclerostin domain containing 1
chr21_+_37420299 0.50 ENST00000455097.6
ENST00000643854.1
ENST00000645424.1
ENST00000642309.1
ENST00000645774.1
ENST00000398956.2
DYRK1A
dual specificity tyrosine phosphorylation regulated kinase 1A
chr12_-_7695752 0.48 ENST00000329913.4
GDF3
growth differentiation factor 3
chr11_-_64744993 0.44 ENST00000377485.5
RASGRP2
RAS guanyl releasing protein 2
chr17_-_2336435 0.44 ENST00000301364.10
ENST00000576112.2
TSR1
TSR1 ribosome maturation factor
chr7_+_76461676 0.43 ENST00000425780.5
ENST00000456590.5
ENST00000451769.5
ENST00000324432.9
ENST00000457529.5
ENST00000446600.5
ENST00000430490.7
ENST00000413936.6
ENST00000423646.5
ENST00000438930.5
DTX2
deltex E3 ubiquitin ligase 2
chr7_-_27130182 0.42 ENST00000511914.1
HOXA4
homeobox A4
chr14_-_21526391 0.36 ENST00000611430.4
SALL2
spalt like transcription factor 2
chr12_-_12684490 0.35 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr1_-_84893166 0.27 ENST00000370611.4
LPAR3
lysophosphatidic acid receptor 3
chr2_-_144430934 0.23 ENST00000638087.1
ENST00000638007.1
ZEB2
zinc finger E-box binding homeobox 2
chr1_+_147902789 0.23 ENST00000369235.2
GJA8
gap junction protein alpha 8
chr15_-_52529050 0.21 ENST00000399231.7
MYO5A
myosin VA
chr6_+_106087580 0.18 ENST00000424894.1
ENST00000648754.1
PRDM1
PR/SET domain 1
chr20_+_46008900 0.18 ENST00000372330.3
MMP9
matrix metallopeptidase 9
chr17_+_40318237 0.13 ENST00000394089.6
ENST00000425707.7
RARA
retinoic acid receptor alpha
chr10_+_31319125 0.11 ENST00000320985.14
ENST00000560721.6
ENST00000558440.5
ENST00000424869.6
ENST00000542815.7
ZEB1
zinc finger E-box binding homeobox 1
chrX_-_53686710 0.06 ENST00000262854.11
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
chr7_-_95324524 0.04 ENST00000222381.8
PON1
paraoxonase 1
chr1_-_43389768 0.04 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
MED8
mediator complex subunit 8
chr11_-_83682385 0.03 ENST00000426717.6
DLG2
discs large MAGUK scaffold protein 2
chr19_+_38899680 0.02 ENST00000576510.5
ENST00000392079.7
NFKBIB
NFKB inhibitor beta
chr11_-_83682414 0.01 ENST00000404783.7
DLG2
discs large MAGUK scaffold protein 2
chr8_-_100336184 0.01 ENST00000519527.5
ENST00000522369.5
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 24.6 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
3.2 9.6 GO:1900195 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
1.6 8.0 GO:0006041 glucosamine metabolic process(GO:0006041)
1.6 4.7 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
1.4 4.2 GO:0060005 vestibular reflex(GO:0060005)
1.4 8.4 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.3 5.2 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
1.2 11.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.2 3.5 GO:0019046 release from viral latency(GO:0019046)
1.2 3.5 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
1.1 7.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.1 4.3 GO:0006258 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of type B pancreatic cell development(GO:2000077)
1.1 5.3 GO:0033058 directional locomotion(GO:0033058)
0.9 8.0 GO:0042118 endothelial cell activation(GO:0042118)
0.8 3.1 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.8 4.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.7 2.8 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) negative regulation of adrenergic receptor signaling pathway(GO:0071878)
0.7 2.8 GO:0072302 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.6 1.8 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.6 6.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.5 2.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.5 1.5 GO:0021997 neural plate axis specification(GO:0021997)
0.5 7.9 GO:0003322 pancreatic A cell development(GO:0003322)
0.5 6.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 2.3 GO:0071233 cellular response to leucine(GO:0071233)
0.4 2.7 GO:0061511 centriole elongation(GO:0061511)
0.4 1.3 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.4 1.3 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.4 2.9 GO:0036343 psychomotor behavior(GO:0036343)
0.4 2.5 GO:1990034 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.4 2.4 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.4 7.0 GO:0006828 manganese ion transport(GO:0006828)
0.4 1.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.4 2.2 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.3 1.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 1.3 GO:1900175 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.3 3.4 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.3 0.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.3 0.9 GO:0021558 midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164)
0.3 3.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.3 0.9 GO:0002461 tolerance induction dependent upon immune response(GO:0002461) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of immature T cell proliferation(GO:0033091) negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.3 4.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 0.8 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.3 5.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.3 1.8 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.2 3.5 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.2 3.3 GO:0016322 neuron remodeling(GO:0016322)
0.2 3.3 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.2 1.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 2.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 2.5 GO:0060539 diaphragm development(GO:0060539)
0.2 4.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 1.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 6.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 2.0 GO:0043589 skin morphogenesis(GO:0043589)
0.2 3.0 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 11.1 GO:0003407 neural retina development(GO:0003407)
0.2 0.6 GO:0072014 proximal tubule development(GO:0072014)
0.1 1.8 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.8 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 2.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 4.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.1 1.2 GO:0009414 response to water deprivation(GO:0009414)
0.1 1.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 3.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 3.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 12.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 0.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 9.0 GO:0030449 regulation of complement activation(GO:0030449)
0.1 1.4 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.3 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.2 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 0.9 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 1.3 GO:0033622 integrin activation(GO:0033622)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.0 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 4.1 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.4 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.5 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 2.9 GO:0021915 neural tube development(GO:0021915)
0.0 0.5 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.5 GO:0000154 rRNA modification(GO:0000154)
0.0 0.0 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) response to fluoride(GO:1902617)
0.0 2.0 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.4 GO:0018022 peptidyl-lysine methylation(GO:0018022)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
1.3 6.6 GO:0097513 myosin II filament(GO:0097513)
1.1 9.6 GO:0072687 meiotic spindle(GO:0072687)
0.9 4.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.8 7.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.7 2.7 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.6 3.8 GO:1990769 proximal neuron projection(GO:1990769)
0.5 13.7 GO:0044295 axonal growth cone(GO:0044295)
0.5 3.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 1.3 GO:1902737 dendritic filopodium(GO:1902737)
0.4 5.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.4 2.5 GO:1990635 proximal dendrite(GO:1990635)
0.3 3.4 GO:0045180 basal cortex(GO:0045180)
0.3 6.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 1.8 GO:0005879 axonemal microtubule(GO:0005879)
0.3 2.1 GO:0036021 endolysosome lumen(GO:0036021)
0.3 3.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.3 1.0 GO:0005899 insulin receptor complex(GO:0005899)
0.3 3.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 1.7 GO:1990130 Iml1 complex(GO:1990130)
0.2 4.6 GO:0016580 Sin3 complex(GO:0016580)
0.2 4.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 3.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 5.7 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 2.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 4.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 4.5 GO:0030057 desmosome(GO:0030057)
0.1 2.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 3.9 GO:0042629 mast cell granule(GO:0042629)
0.1 6.4 GO:0015030 Cajal body(GO:0015030)
0.1 12.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.8 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.9 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 12.9 GO:0043235 receptor complex(GO:0043235)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0034706 sodium channel complex(GO:0034706)
0.0 6.7 GO:0005770 late endosome(GO:0005770)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 2.1 GO:0005884 actin filament(GO:0005884)
0.0 4.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 4.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 5.7 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 25.2 GO:0035939 microsatellite binding(GO:0035939)
3.2 9.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
2.1 6.3 GO:0035375 zymogen binding(GO:0035375)
1.8 11.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.6 4.7 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.9 2.8 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938) alpha-2C adrenergic receptor binding(GO:0031696)
0.8 7.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.6 1.8 GO:0031862 prostanoid receptor binding(GO:0031862)
0.6 2.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.5 5.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.5 6.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.5 1.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.4 3.5 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.4 1.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.4 2.3 GO:0070728 leucine binding(GO:0070728)
0.3 6.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 4.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 1.3 GO:0034046 poly(G) binding(GO:0034046)
0.2 3.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 1.5 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.2 1.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 4.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 4.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 0.8 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 4.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 0.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.5 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 2.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 2.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 1.3 GO:0016015 morphogen activity(GO:0016015)
0.1 9.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 3.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 5.4 GO:0030332 cyclin binding(GO:0030332)
0.1 3.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 6.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 5.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.5 GO:0070402 NADPH binding(GO:0070402)
0.1 3.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 12.7 GO:0001618 virus receptor activity(GO:0001618)
0.1 3.5 GO:0004532 exoribonuclease activity(GO:0004532)
0.1 7.7 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 10.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 3.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.6 GO:0005537 mannose binding(GO:0005537)
0.1 3.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.9 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 2.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.5 GO:0036122 BMP binding(GO:0036122)
0.1 5.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 7.9 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 4.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.4 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 5.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 4.4 GO:0003924 GTPase activity(GO:0003924)
0.0 2.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.3 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.0 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 22.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 9.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 12.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 6.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 3.9 PID REELIN PATHWAY Reelin signaling pathway
0.1 12.9 PID FGF PATHWAY FGF signaling pathway
0.1 1.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 3.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 2.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 4.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 7.9 PID CDC42 PATHWAY CDC42 signaling events
0.1 7.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 ST GAQ PATHWAY G alpha q Pathway
0.0 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 6.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 4.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.4 6.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4 8.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 3.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3 6.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 20.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 9.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 7.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 4.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 5.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 11.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 1.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 2.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 3.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.8 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.1 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 3.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing