ISMARA results: REL

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for REL

Z-value: 1.94

Motif logo

Transcription factors associated with REL

Gene Symbol	Gene ID	Gene Info
REL Ensembl NCBI GeneCards UniProt	ENSG00000162924.15	REL

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
REL	hg38_v1_chr2_+_60881515_60881552, hg38_v1_chr2_+_60881553_60881619	0.29	1.5e-05	Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr6_+_137867241 Show fit	43.50	ENST00000612899.5 ENST00000420009.5	TNFAIP3 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chr6_+_137867414 Show fit	42.53	ENST00000237289.8 ENST00000433680.1	TNFAIP3 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chrX_-_154371210 Show fit	25.03	ENST00000369856.8 ENST00000422373.6 ENST00000360319.9	FLNA Ensembl NCBI GeneCards UniProt Show fit	filamin A
chr1_-_159924529 Show fit	24.43	ENST00000320307.8	TAGLN2 Ensembl NCBI GeneCards UniProt Show fit	transgelin 2
chr17_-_4949037 Show fit	24.00	ENST00000572383.1	PFN1 Ensembl NCBI GeneCards UniProt Show fit	profilin 1
chr12_+_51238854 Show fit	22.57	ENST00000549732.6 ENST00000604900.5	DAZAP2 Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 2
chr11_-_58578096 Show fit	22.49	ENST00000528954.5 ENST00000528489.1	LPXN Ensembl NCBI GeneCards UniProt Show fit	leupaxin
chr10_+_17229267 Show fit	22.26	ENST00000224237.9	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr5_-_151087131 Show fit	21.11	ENST00000315050.11 ENST00000523338.5 ENST00000522100.5	TNIP1 Ensembl NCBI GeneCards UniProt Show fit	TNFAIP3 interacting protein 1
chr1_-_159925496 Show fit	20.75	ENST00000368097.9	TAGLN2 Ensembl NCBI GeneCards UniProt Show fit	transgelin 2
chr18_+_3252267 Show fit	18.27	ENST00000536605.1 ENST00000580887.5	MYL12A Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12A
chr2_-_89143133 Show fit	17.61	ENST00000492167.1	IGKV3-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-20
chr2_-_89085787 Show fit	15.94	ENST00000390252.2	IGKV3-15 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-15
chr12_+_51238724 Show fit	14.15	ENST00000449723.7 ENST00000549555.5 ENST00000439799.6 ENST00000412716.8 ENST00000425012.6	DAZAP2 Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 2
chr2_+_90114838 Show fit	14.05	ENST00000417279.3	IGKV3D-15 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-15
chr6_-_31582415 Show fit	13.90	ENST00000429299.3 ENST00000446745.2	LTB Ensembl NCBI GeneCards UniProt Show fit	lymphotoxin beta
chr12_-_48924919 Show fit	13.65	ENST00000444214.6	FKBP11 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 11
chr10_+_17228215 Show fit	13.36	ENST00000544301.7	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr2_-_88979016 Show fit	12.77	ENST00000390247.2	IGKV3-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-7 (non-functional)
chr14_-_68979436 Show fit	12.58	ENST00000193403.10	ACTN1 Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr1_+_16440700 Show fit	12.52	ENST00000504551.6 ENST00000457722.6 ENST00000337132.10 ENST00000443980.6	NECAP2 Ensembl NCBI GeneCards UniProt Show fit	NECAP endocytosis associated 2
chr15_-_60397964 Show fit	12.29	ENST00000558998.5 ENST00000560165.5 ENST00000557986.5 ENST00000559467.5 ENST00000677968.1 ENST00000678450.1 ENST00000332680.8 ENST00000396024.7 ENST00000557906.6 ENST00000558558.6 ENST00000559113.6 ENST00000559780.6 ENST00000559956.6 ENST00000560468.6 ENST00000678870.1 ENST00000678061.1 ENST00000451270.7 ENST00000421017.6 ENST00000560466.5 ENST00000558132.5 ENST00000559370.5 ENST00000559725.5 ENST00000558985.6 ENST00000679109.1	ANXA2 Ensembl NCBI GeneCards UniProt Show fit	annexin A2
chr11_+_102317450 Show fit	11.91	ENST00000615299.4 ENST00000527309.2 ENST00000526421.6 ENST00000263464.9	BIRC3 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr6_+_32854179 Show fit	11.90	ENST00000374859.3	PSMB9 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 9
chr2_-_89010515 Show fit	11.77	ENST00000493819.1	IGKV1-9 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr1_-_112707314 Show fit	11.66	ENST00000369642.7	RHOC Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member C
chr19_-_49640092 Show fit	11.54	ENST00000246792.4	RRAS Ensembl NCBI GeneCards UniProt Show fit	RAS related
chr1_-_64966488 Show fit	11.48	ENST00000342505.5 ENST00000673254.1	JAK1 Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 1
chr12_+_55818033 Show fit	11.41	ENST00000552672.5 ENST00000243045.10 ENST00000550836.1	ORMDL2 Ensembl NCBI GeneCards UniProt Show fit	ORMDL sphingolipid biosynthesis regulator 2
chr11_+_102317542 Show fit	11.13	ENST00000532808.5	BIRC3 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr17_-_7687427 Show fit	10.91	ENST00000514944.5 ENST00000503591.1 ENST00000610292.4 ENST00000420246.6 ENST00000455263.6 ENST00000610538.4 ENST00000622645.4 ENST00000445888.6 ENST00000619485.4 ENST00000509690.5 ENST00000604348.5 ENST00000269305.9 ENST00000620739.4	TP53 Ensembl NCBI GeneCards UniProt Show fit	tumor protein p53
chr3_-_49104745 Show fit	10.48	ENST00000635194.1 ENST00000306125.12 ENST00000634602.1 ENST00000414533.5 ENST00000635443.1 ENST00000452739.5 ENST00000635231.1	QARS1 Ensembl NCBI GeneCards UniProt Show fit	glutaminyl-tRNA synthetase 1
chr2_+_69742125 Show fit	10.48	ENST00000394295.6	ANXA4 Ensembl NCBI GeneCards UniProt Show fit	annexin A4
chr20_-_35284745 Show fit	10.45	ENST00000374443.7 ENST00000374450.8	EIF6 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 6
chr18_+_23949847 Show fit	10.40	ENST00000588004.1	LAMA3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 3
chr20_-_35284715 Show fit	10.27	ENST00000374436.7 ENST00000675032.1	EIF6 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 6
chr12_-_9760893 Show fit	10.22	ENST00000228434.7 ENST00000536709.1	CD69 Ensembl NCBI GeneCards UniProt Show fit	CD69 molecule
chr2_+_90038848 Show fit	10.20	ENST00000390270.2	IGKV3D-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-20
chr8_-_47738153 Show fit	10.08	ENST00000408965.4	CEBPD Ensembl NCBI GeneCards UniProt Show fit	CCAAT enhancer binding protein delta
chr19_+_41219177 Show fit	10.01	ENST00000301178.9	AXL Ensembl NCBI GeneCards UniProt Show fit	AXL receptor tyrosine kinase
chr3_+_172039556 Show fit	9.98	ENST00000415807.7 ENST00000421757.5	FNDC3B Ensembl NCBI GeneCards UniProt Show fit	fibronectin type III domain containing 3B
chr14_-_35404650 Show fit	9.67	ENST00000553342.1 ENST00000557140.5 ENST00000216797.10	NFKBIA Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor alpha
chr4_-_102828022 Show fit	9.63	ENST00000502690.5	UBE2D3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr9_-_130043154 Show fit	9.49	ENST00000355681.3 ENST00000446176.7 ENST00000443566.6 ENST00000420781.5	FNBP1 Ensembl NCBI GeneCards UniProt Show fit	formin binding protein 1
chr3_-_49104457 Show fit	9.49	ENST00000635292.1 ENST00000635541.1 ENST00000464962.6	QARS1 Ensembl NCBI GeneCards UniProt Show fit	glutaminyl-tRNA synthetase 1
chr9_-_115118145 Show fit	9.30	ENST00000350763.9	TNC Ensembl NCBI GeneCards UniProt Show fit	tenascin C
chr4_+_73869385 Show fit	9.14	ENST00000395761.4	CXCL1 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 1
chr14_+_103123452 Show fit	9.14	ENST00000558056.1 ENST00000560869.6	TNFAIP2 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 2
chr4_-_102828048 Show fit	9.09	ENST00000508249.1	UBE2D3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr21_+_33403391 Show fit	9.05	ENST00000290219.11 ENST00000381995.5	IFNGR2 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr9_-_115118198 Show fit	9.03	ENST00000534839.1 ENST00000535648.5	TNC Ensembl NCBI GeneCards UniProt Show fit	tenascin C
chr14_-_106658251 Show fit	8.96	ENST00000454421.2	IGHV3-64 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64
chr21_+_33403466 Show fit	8.39	ENST00000405436.5	IFNGR2 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr13_-_98577131 Show fit	8.37	ENST00000397517.6	STK24 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 24
chr3_-_177197210 Show fit	8.14	ENST00000431421.5 ENST00000422066.5 ENST00000413084.5 ENST00000673974.1 ENST00000422442.6	TBL1XR1 Ensembl NCBI GeneCards UniProt Show fit	TBL1X receptor 1
chr17_+_36211055 Show fit	8.12	ENST00000617405.5 ENST00000617416.4 ENST00000613173.4 ENST00000620732.4 ENST00000620098.4 ENST00000620576.4 ENST00000620055.4 ENST00000610565.4 ENST00000620250.1	CCL4L2 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 4 like 2
chr17_-_75182536 Show fit	8.06	ENST00000578238.2	SUMO2 Ensembl NCBI GeneCards UniProt Show fit	small ubiquitin like modifier 2
chr16_+_27313879 Show fit	8.02	ENST00000562142.5 ENST00000561742.5 ENST00000543915.6 ENST00000395762.7 ENST00000563002.5	IL4R Ensembl NCBI GeneCards UniProt Show fit	interleukin 4 receptor
chr11_-_64245816 Show fit	8.02	ENST00000542235.1	PPP1R14B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 14B
chr12_+_6946468 Show fit	7.95	ENST00000543115.5 ENST00000399448.5	PTPN6 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr12_-_122500520 Show fit	7.89	ENST00000540586.1 ENST00000543897.5	ZCCHC8 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCHC-type containing 8
chr8_-_48921419 Show fit	7.58	ENST00000020945.4	SNAI2 Ensembl NCBI GeneCards UniProt Show fit	snail family transcriptional repressor 2
chr4_-_184474518 Show fit	7.49	ENST00000393593.8	IRF2 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 2
chr5_-_150412743 Show fit	7.46	ENST00000353334.11 ENST00000009530.12 ENST00000377795.7	CD74 Ensembl NCBI GeneCards UniProt Show fit	CD74 molecule
chr14_-_34630109 Show fit	7.29	ENST00000396526.7	SNX6 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 6
chr10_+_102395693 Show fit	7.26	ENST00000652277.1 ENST00000189444.11 ENST00000661543.1	NFKB2 Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 2
chr14_-_68979314 Show fit	7.24	ENST00000684713.1 ENST00000683198.1 ENST00000684598.1 ENST00000682331.1 ENST00000682291.1 ENST00000683342.1	ACTN1 Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr3_+_52685995 Show fit	7.20	ENST00000394799.6 ENST00000418458.6	GNL3 Ensembl NCBI GeneCards UniProt Show fit	G protein nucleolar 3
chr19_+_33373694 Show fit	7.15	ENST00000284000.9	CEBPG Ensembl NCBI GeneCards UniProt Show fit	CCAAT enhancer binding protein gamma
chr2_-_88947820 Show fit	7.14	ENST00000496168.1	IGKV1-5 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-5
chr17_-_63842663 Show fit	7.07	ENST00000613943.4 ENST00000448276.7	SMARCD2 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr11_+_102317492 Show fit	7.07	ENST00000673846.1	BIRC3 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr10_+_88990531 Show fit	6.97	ENST00000355740.7	FAS Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr7_+_26201705 Show fit	6.90	ENST00000396386.7 ENST00000456948.5 ENST00000409747.5	CBX3 Ensembl NCBI GeneCards UniProt Show fit	chromobox 3
chr2_+_161308407 Show fit	6.89	ENST00000409682.8	PSMD14 Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 14
chr4_+_168497044 Show fit	6.82	ENST00000505667.6	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr4_+_168497066 Show fit	6.77	ENST00000261509.10	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr10_+_88990621 Show fit	6.66	ENST00000352159.8	FAS Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr14_-_34630124 Show fit	6.58	ENST00000362031.10 ENST00000557265.6 ENST00000652385.1	SNX6 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 6
chr10_-_29634964 Show fit	6.49	ENST00000375398.6 ENST00000355867.8	SVIL Ensembl NCBI GeneCards UniProt Show fit	supervillin
chr4_-_74099187 Show fit	6.13	ENST00000508487.3	CXCL2 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 2
chr2_+_227813834 Show fit	6.12	ENST00000358813.5 ENST00000409189.7	CCL20 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 20
chr7_-_16804987 Show fit	6.05	ENST00000401412.5 ENST00000419304.7	AGR2 Ensembl NCBI GeneCards UniProt Show fit	anterior gradient 2, protein disulphide isomerase family member
chr21_+_33266350 Show fit	6.03	ENST00000290200.7	IL10RB Ensembl NCBI GeneCards UniProt Show fit	interleukin 10 receptor subunit beta
chr2_-_43226594 Show fit	6.00	ENST00000282388.4	ZFP36L2 Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein like 2
chr11_+_66638661 Show fit	5.97	ENST00000396053.9 ENST00000408993.6	RBM4 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 4
chr2_-_191020960 Show fit	5.88	ENST00000432058.1	STAT1 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 1
chr11_+_114296347 Show fit	5.86	ENST00000299964.4	NNMT Ensembl NCBI GeneCards UniProt Show fit	nicotinamide N-methyltransferase
chr1_-_29181809 Show fit	5.82	ENST00000466448.4 ENST00000373795.7	SRSF4 Ensembl NCBI GeneCards UniProt Show fit	serine and arginine rich splicing factor 4
chr1_-_35193135 Show fit	5.73	ENST00000357214.6	SFPQ Ensembl NCBI GeneCards UniProt Show fit	splicing factor proline and glutamine rich
chr17_+_36210924 Show fit	5.72	ENST00000615418.4	CCL4L2 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 4 like 2
chr12_+_51239278 Show fit	5.70	ENST00000551313.1	DAZAP2 Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 2
chr6_-_31806937 Show fit	5.64	ENST00000375661.6	LSM2 Ensembl NCBI GeneCards UniProt Show fit	LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr10_-_26860922 Show fit	5.47	ENST00000376142.6 ENST00000359188.8 ENST00000376140.4 ENST00000376139.6 ENST00000376160.5	ABI1 Ensembl NCBI GeneCards UniProt Show fit	abl interactor 1
chr3_-_177197429 Show fit	5.40	ENST00000457928.7	TBL1XR1 Ensembl NCBI GeneCards UniProt Show fit	TBL1X receptor 1
chr14_+_64503943 Show fit	5.28	ENST00000556965.1 ENST00000554015.5	ZBTB1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 1
chr22_-_27919199 Show fit	5.24	ENST00000634017.1 ENST00000436663.1 ENST00000320996.14 ENST00000335272.10 ENST00000455418.7	PITPNB Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol transfer protein beta
chr1_-_31938302 Show fit	5.17	ENST00000647444.2	PTP4A2 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A2
chr7_+_150368189 Show fit	5.15	ENST00000519397.1 ENST00000479668.5	REPIN1 Ensembl NCBI GeneCards UniProt Show fit	replication initiator 1
chr5_-_131165272 Show fit	5.10	ENST00000675491.1 ENST00000506908.2	HINT1 Ensembl NCBI GeneCards UniProt Show fit	histidine triad nucleotide binding protein 1
chr10_+_88990736 Show fit	5.08	ENST00000357339.6 ENST00000652046.1 ENST00000355279.2	FAS Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr12_-_122500924 Show fit	5.04	ENST00000633063.3	ZCCHC8 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCHC-type containing 8
chr1_-_27490130 Show fit	5.03	ENST00000618852.5	WASF2 Ensembl NCBI GeneCards UniProt Show fit	WASP family member 2
chr3_+_153162196 Show fit	5.02	ENST00000323534.5	RAP2B Ensembl NCBI GeneCards UniProt Show fit	RAP2B, member of RAS oncogene family
chr11_-_65614195 Show fit	4.95	ENST00000309100.8 ENST00000529839.1 ENST00000526293.1	MAP3K11 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 11
chr1_+_24745396 Show fit	4.92	ENST00000374379.9	CLIC4 Ensembl NCBI GeneCards UniProt Show fit	chloride intracellular channel 4
chr4_-_102827723 Show fit	4.87	ENST00000349311.12	UBE2D3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr12_-_122500947 Show fit	4.79	ENST00000672018.1	ZCCHC8 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCHC-type containing 8
chr10_-_94362925 Show fit	4.72	ENST00000371361.3	NOC3L Ensembl NCBI GeneCards UniProt Show fit	NOC3 like DNA replication regulator
chr19_+_14031746 Show fit	4.69	ENST00000263379.4	IL27RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 27 receptor subunit alpha
chr2_+_207529892 Show fit	4.64	ENST00000432329.6 ENST00000445803.5	CREB1 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 1
chr3_-_69080350 Show fit	4.61	ENST00000630585.1 ENST00000361055.9 ENST00000415609.6 ENST00000349511.8	UBA3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin like modifier activating enzyme 3
chr1_-_209651291 Show fit	4.58	ENST00000391911.5 ENST00000415782.1	LAMB3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 3
chr4_-_102828159 Show fit	4.50	ENST00000394803.9	UBE2D3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr2_+_161160420 Show fit	4.39	ENST00000392749.7 ENST00000405852.5	TANK Ensembl NCBI GeneCards UniProt Show fit	TRAF family member associated NFKB activator
chr5_-_131165231 Show fit	4.35	ENST00000675100.1 ENST00000304043.10 ENST00000513012.2	HINT1 Ensembl NCBI GeneCards UniProt Show fit	histidine triad nucleotide binding protein 1
chr19_-_6591103 Show fit	4.35	ENST00000423145.7 ENST00000245903.4	CD70 Ensembl NCBI GeneCards UniProt Show fit	CD70 molecule
chr4_-_102827948 Show fit	4.33	ENST00000394804.6 ENST00000394801.8	UBE2D3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr12_+_101877571 Show fit	4.13	ENST00000258534.13	DRAM1 Ensembl NCBI GeneCards UniProt Show fit	DNA damage regulated autophagy modulator 1
chr12_-_6607397 Show fit	4.06	ENST00000645005.1 ENST00000646806.1	CHD4 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 4
chr13_-_51453015 Show fit	4.03	ENST00000442263.4 ENST00000311234.9	INTS6 Ensembl NCBI GeneCards UniProt Show fit	integrator complex subunit 6
chr5_+_112976757 Show fit	3.97	ENST00000389063.3	DCP2 Ensembl NCBI GeneCards UniProt Show fit	decapping mRNA 2
chr8_+_69492793 Show fit	3.96	ENST00000616868.1 ENST00000419716.7 ENST00000402687.9	SULF1 Ensembl NCBI GeneCards UniProt Show fit	sulfatase 1
chr2_+_207529731 Show fit	3.93	ENST00000430624.5	CREB1 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 1
chrX_+_118727575 Show fit	3.93	ENST00000371642.1 ENST00000371666.8	IL13RA1 Ensembl NCBI GeneCards UniProt Show fit	interleukin 13 receptor subunit alpha 1
chr6_-_29559724 Show fit	3.90	ENST00000377050.5	UBD Ensembl NCBI GeneCards UniProt Show fit	ubiquitin D
chr12_-_6607334 Show fit	3.53	ENST00000645645.1 ENST00000357008.7 ENST00000544484.6 ENST00000544040.7	CHD4 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 4
chr4_-_73998669 Show fit	3.50	ENST00000296027.5	CXCL5 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 5
chr17_+_51260520 Show fit	3.47	ENST00000225298.12	UTP18 Ensembl NCBI GeneCards UniProt Show fit	UTP18 small subunit processome component
chr16_+_2770911 Show fit	3.39	ENST00000570539.1	SRRM2 Ensembl NCBI GeneCards UniProt Show fit	serine/arginine repetitive matrix 2
chr1_-_26890237 Show fit	3.34	ENST00000431781.2 ENST00000374135.9	GPN2 Ensembl NCBI GeneCards UniProt Show fit	GPN-loop GTPase 2
chr1_-_36149450 Show fit	3.28	ENST00000373163.5	TRAPPC3 Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3
chr2_-_88055722 Show fit	3.19	ENST00000347055.4	KRCC1 Ensembl NCBI GeneCards UniProt Show fit	lysine rich coiled-coil 1
chr2_+_219229783 Show fit	3.18	ENST00000453432.5 ENST00000409849.5 ENST00000323348.10 ENST00000416565.1 ENST00000410034.7 ENST00000447157.5	ANKZF1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
chr1_+_63367619 Show fit	3.16	ENST00000263440.6	ALG6 Ensembl NCBI GeneCards UniProt Show fit	ALG6 alpha-1,3-glucosyltransferase
chr8_-_23854796 Show fit	3.15	ENST00000290271.7	STC1 Ensembl NCBI GeneCards UniProt Show fit	stanniocalcin 1
chr15_+_52019206 Show fit	3.07	ENST00000681888.1 ENST00000261845.7 ENST00000680066.1 ENST00000680777.1 ENST00000680652.1	MAPK6 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 6
chr15_+_85380565 Show fit	3.07	ENST00000559362.5 ENST00000394518.7	AKAP13 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 13
chrX_-_48897747 Show fit	3.05	ENST00000490755.2 ENST00000465150.6 ENST00000495490.6	TIMM17B Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 17B
chr17_+_42288429 Show fit	3.02	ENST00000676631.1 ENST00000677893.1	STAT5A Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr1_-_31644866 Show fit	2.98	ENST00000373703.5	PEF1 Ensembl NCBI GeneCards UniProt Show fit	penta-EF-hand domain containing 1
chr13_-_48095096 Show fit	2.98	ENST00000258648.7 ENST00000378586.5	MED4 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 4
chr5_+_50667405 Show fit	2.96	ENST00000505554.5	PARP8 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 8
chr19_+_41219235 Show fit	2.86	ENST00000359092.7	AXL Ensembl NCBI GeneCards UniProt Show fit	AXL receptor tyrosine kinase
chr10_+_102394488 Show fit	2.85	ENST00000369966.8	NFKB2 Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 2
chrX_+_48897900 Show fit	2.84	ENST00000376566.8 ENST00000376563.5	PQBP1 Ensembl NCBI GeneCards UniProt Show fit	polyglutamine binding protein 1
chr17_-_8383164 Show fit	2.76	ENST00000584164.6 ENST00000582556.5 ENST00000648839.1 ENST00000578812.5 ENST00000583011.6	RPL26 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L26
chr2_-_74465162 Show fit	2.70	ENST00000649854.1 ENST00000650523.1 ENST00000649601.1 ENST00000448666.7 ENST00000409065.5 ENST00000414701.1 ENST00000452063.7 ENST00000649075.1 ENST00000648810.1 ENST00000462443.2	MOGS Ensembl NCBI GeneCards UniProt Show fit	mannosyl-oligosaccharide glucosidase
chr22_+_22195753 Show fit	2.67	ENST00000390285.4	IGLV6-57 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 6-57
chr2_-_98663464 Show fit	2.67	ENST00000414521.6	MGAT4A Ensembl NCBI GeneCards UniProt Show fit	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr11_+_10455292 Show fit	2.58	ENST00000396553.6	AMPD3 Ensembl NCBI GeneCards UniProt Show fit	adenosine monophosphate deaminase 3
chr3_+_184363351 Show fit	2.56	ENST00000443489.5	POLR2H Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II, I and III subunit H
chr12_-_57110284 Show fit	2.56	ENST00000543873.6 ENST00000554663.5 ENST00000557635.5	STAT6 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 6
chr10_+_87659839 Show fit	2.54	ENST00000456849.2	PAPSS2 Ensembl NCBI GeneCards UniProt Show fit	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr6_-_130970428 Show fit	2.51	ENST00000529208.5	EPB41L2 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr4_+_73836667 Show fit	2.47	ENST00000226317.10	CXCL6 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 6
chr14_-_73458519 Show fit	2.45	ENST00000356296.8 ENST00000557597.5 ENST00000554394.5 ENST00000555238.6 ENST00000555987.5 ENST00000555394.5 ENST00000554546.5	NUMB Ensembl NCBI GeneCards UniProt Show fit	NUMB endocytic adaptor protein
chr11_-_128522189 Show fit	2.40	ENST00000526145.6	ETS1 Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr2_-_28870266 Show fit	2.35	ENST00000306108.10	TRMT61B Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 61B
chr7_-_82443715 Show fit	2.30	ENST00000356253.9 ENST00000423588.1	CACNA2D1 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr19_+_2476118 Show fit	2.29	ENST00000215631.9 ENST00000587345.1	GADD45B Ensembl NCBI GeneCards UniProt Show fit	growth arrest and DNA damage inducible beta
chr14_-_21383989 Show fit	2.20	ENST00000216297.7	SUPT16H Ensembl NCBI GeneCards UniProt Show fit	SPT16 homolog, facilitates chromatin remodeling subunit
chr2_+_60881553 Show fit	2.17	ENST00000394479.4	REL Ensembl NCBI GeneCards UniProt Show fit	REL proto-oncogene, NF-kB subunit
chr9_+_128149447 Show fit	2.17	ENST00000277480.7 ENST00000372998.1	LCN2 Ensembl NCBI GeneCards UniProt Show fit	lipocalin 2
chr15_+_85380672 Show fit	2.13	ENST00000361243.6 ENST00000560256.1	AKAP13 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 13
chr17_+_42288464 Show fit	2.12	ENST00000590726.7 ENST00000678903.1 ENST00000590949.6 ENST00000676585.1 ENST00000588868.5	STAT5A Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr2_+_207529934 Show fit	2.12	ENST00000421139.5 ENST00000353267.8	CREB1 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 1
chr1_-_36149464 Show fit	2.11	ENST00000373166.8 ENST00000373159.1 ENST00000373162.5 ENST00000616074.4 ENST00000616395.4	TRAPPC3 Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3
chr3_-_184249520 Show fit	2.08	ENST00000455059.5 ENST00000445626.6	ALG3 Ensembl NCBI GeneCards UniProt Show fit	ALG3 alpha-1,3- mannosyltransferase
chr22_+_22162155 Show fit	2.03	ENST00000390284.2	IGLV4-60 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 4-60
chr1_+_200894892 Show fit	1.89	ENST00000413687.3	INAVA Ensembl NCBI GeneCards UniProt Show fit	innate immunity activator
chr6_+_10694916 Show fit	1.87	ENST00000379568.4	PAK1IP1 Ensembl NCBI GeneCards UniProt Show fit	PAK1 interacting protein 1
chr16_-_15643024 Show fit	1.82	ENST00000540441.6	MARF1 Ensembl NCBI GeneCards UniProt Show fit	meiosis regulator and mRNA stability factor 1
chr18_+_23873000 Show fit	1.79	ENST00000269217.11 ENST00000587184.5	LAMA3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 3
chr2_+_60881515 Show fit	1.68	ENST00000295025.12	REL Ensembl NCBI GeneCards UniProt Show fit	REL proto-oncogene, NF-kB subunit
chr12_+_122980060 Show fit	1.68	ENST00000543566.6 ENST00000453766.7 ENST00000392435.7 ENST00000413381.6 ENST00000426960.6	ARL6IP4 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 6 interacting protein 4
chr6_+_31715339 Show fit	1.68	ENST00000375824.1 ENST00000375825.7	LY6G6D Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 6 family member G6D
chr11_-_128522285 Show fit	1.64	ENST00000319397.6 ENST00000535549.5	ETS1 Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr15_-_39920248 Show fit	1.59	ENST00000561100.2	GPR176 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 176
chr14_-_54489003 Show fit	1.57	ENST00000554908.5 ENST00000616146.4	GMFB Ensembl NCBI GeneCards UniProt Show fit	glia maturation factor beta
chr12_+_122980486 Show fit	1.40	ENST00000454885.6	ARL6IP4 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 6 interacting protein 4
chr5_+_43603163 Show fit	1.35	ENST00000660752.1 ENST00000654405.1 ENST00000344920.9 ENST00000657172.1 ENST00000512996.6 ENST00000671668.1	NNT Ensembl NCBI GeneCards UniProt Show fit	nicotinamide nucleotide transhydrogenase
chr11_-_128522264 Show fit	1.31	ENST00000531611.5	ETS1 Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr6_+_292050 Show fit	1.30	ENST00000344450.9	DUSP22 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 22
chr6_+_144150492 Show fit	1.26	ENST00000367568.5	STX11 Ensembl NCBI GeneCards UniProt Show fit	syntaxin 11
chr20_+_45174894 Show fit	1.25	ENST00000243924.4	PI3 Ensembl NCBI GeneCards UniProt Show fit	peptidase inhibitor 3
chr12_-_66678934 Show fit	1.24	ENST00000545666.5 ENST00000398016.7 ENST00000359742.9 ENST00000538211.5	GRIP1 Ensembl NCBI GeneCards UniProt Show fit	glutamate receptor interacting protein 1
chr16_-_15643105 Show fit	1.23	ENST00000548025.5 ENST00000551742.5 ENST00000396368.8	MARF1 Ensembl NCBI GeneCards UniProt Show fit	meiosis regulator and mRNA stability factor 1
chr14_-_25010604 Show fit	1.20	ENST00000550887.5	STXBP6 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 6
chr3_+_179604785 Show fit	1.20	ENST00000611971.4 ENST00000493866.5 ENST00000259037.8 ENST00000472629.5 ENST00000482604.5	NDUFB5 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B5
chr11_+_105610066 Show fit	1.15	ENST00000282499.10 ENST00000393127.6 ENST00000527669.1	GRIA4 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 4
chr14_-_67674583 Show fit	1.14	ENST00000554659.6	VTI1B Ensembl NCBI GeneCards UniProt Show fit	vesicle transport through interaction with t-SNAREs 1B
chr3_+_89107613 Show fit	1.14	ENST00000336596.7	EPHA3 Ensembl NCBI GeneCards UniProt Show fit	EPH receptor A3
chr2_-_18560616 Show fit	1.10	ENST00000381249.4	RDH14 Ensembl NCBI GeneCards UniProt Show fit	retinol dehydrogenase 14
chr10_-_95693936 Show fit	1.00	ENST00000680709.1 ENST00000680353.1 ENST00000679566.1 ENST00000614499.5	TCTN3 Ensembl NCBI GeneCards UniProt Show fit	tectonic family member 3
chr4_-_74038681 Show fit	0.98	ENST00000296026.4	CXCL3 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 3
chr5_-_37840035 Show fit	0.95	ENST00000326524.7	GDNF Ensembl NCBI GeneCards UniProt Show fit	glial cell derived neurotrophic factor
chr5_-_59768631 Show fit	0.94	ENST00000502575.1 ENST00000507116.5	PDE4D Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D
chrX_+_116436599 Show fit	0.91	ENST00000598581.3	SLC6A14 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 14
chr10_+_30434021 Show fit	0.90	ENST00000542547.5	MAP3K8 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
28.7	86.0	GO:0034147	regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
8.3	25.0	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
6.1	18.3	GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
4.1	20.7	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
3.8	30.4	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
3.8	11.4	GO:1900060	negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
3.8	7.6	GO:1901420	negative regulation of response to alcohol(GO:1901420)
3.6	10.9	GO:0051097	negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
2.7	35.6	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
2.7	10.7	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
2.5	10.1	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
2.5	30.1	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
2.5	7.5	GO:0035691	macrophage migration inhibitory factor signaling pathway(GO:0035691)
2.5	12.3	GO:0044111	development involved in symbiotic interaction(GO:0044111)
2.4	9.7	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
2.3	18.7	GO:0036337	Fas signaling pathway(GO:0036337)
2.3	11.7	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
2.3	25.1	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
2.1	12.9	GO:0048549	positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
2.0	6.1	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
2.0	8.0	GO:1990834	response to odorant(GO:1990834)
2.0	13.9	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
2.0	5.9	GO:2000697	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
1.8	24.0	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
1.8	5.3	GO:2000176	regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
1.7	13.9	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
1.5	13.5	GO:0060613	fat pad development(GO:0060613)
1.5	10.5	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
1.2	6.0	GO:0060480	lung goblet cell differentiation(GO:0060480)
1.2	6.0	GO:0097167	circadian regulation of translation(GO:0097167)
1.2	4.6	GO:0007113	endomitotic cell cycle(GO:0007113)
1.1	3.3	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
1.1	7.6	GO:0072553	terminal button organization(GO:0072553)
1.0	10.3	GO:0051601	exocyst localization(GO:0051601)
1.0	3.0	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
1.0	5.7	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.9	19.8	GO:0051764	actin crosslink formation(GO:0051764)
0.9	6.0	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.8	2.5	GO:0000103	sulfate assimilation(GO:0000103)
0.8	28.8	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.8	3.2	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.8	7.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.8	2.4	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
0.7	5.1	GO:0000255	allantoin metabolic process(GO:0000255)
0.7	13.6	GO:0003334	keratinocyte development(GO:0003334)
0.7	19.7	GO:0003094	glomerular filtration(GO:0003094)
0.7	2.7	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.6	3.9	GO:0070842	aggresome assembly(GO:0070842)
0.6	2.6	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.6	8.1	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.6	5.0	GO:0007256	activation of JNKK activity(GO:0007256)
0.6	10.5	GO:0035855	megakaryocyte development(GO:0035855)
0.6	2.5	GO:0030862	positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.6	27.6	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.6	16.8	GO:0031581	hemidesmosome assembly(GO:0031581)
0.6	5.3	GO:0030578	PML body organization(GO:0030578)
0.6	2.8	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.5	7.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.5	16.3	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.5	4.7	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.5	2.3	GO:0086048	membrane depolarization during bundle of His cell action potential(GO:0086048)
0.4	10.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.4	4.0	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.4	2.2	GO:0015891	response to mycotoxin(GO:0010046) iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4	2.6	GO:0006196	AMP catabolic process(GO:0006196)
0.4	1.8	GO:0006740	NADPH regeneration(GO:0006740)
0.3	5.9	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3	54.1	GO:0002377	immunoglobulin production(GO:0002377)
0.3	0.6	GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) negative regulation of osteoclast proliferation(GO:0090291) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.3	9.3	GO:0006337	nucleosome disassembly(GO:0006337)
0.3	0.5	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.3	5.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3	3.5	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.2	13.6	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.2	17.8	GO:0070527	platelet aggregation(GO:0070527)
0.2	1.0	GO:0060676	ureteric bud formation(GO:0060676) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.2	5.0	GO:0032486	Rap protein signal transduction(GO:0032486)
0.2	46.3	GO:0002576	platelet degranulation(GO:0002576)
0.2	5.6	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2	28.0	GO:0006958	complement activation, classical pathway(GO:0006958)
0.2	6.9	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.2	0.8	GO:0046671	negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.2	1.6	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2	0.8	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.2	3.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.2	4.0	GO:0016180	snRNA processing(GO:0016180)
0.2	8.1	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.2	9.5	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.1	0.4	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1	11.8	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.1	6.5	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	4.8	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1	0.8	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.1	1.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	2.5	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.5	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
0.1	3.1	GO:0007143	female meiotic division(GO:0007143)
0.1	0.5	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.1	0.5	GO:0061084	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1	2.7	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.9	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	0.2	GO:0032499	detection of peptidoglycan(GO:0032499) positive regulation of gamma-delta T cell activation(GO:0046645) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1	0.4	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	3.5	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	0.3	GO:1903412	response to bile acid(GO:1903412)
0.1	2.6	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1	7.7	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.1	1.3	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1	7.4	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.1	0.2	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.1	0.6	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.7	GO:0015884	folic acid transport(GO:0015884)
0.1	5.2	GO:0015914	phospholipid transport(GO:0015914)
0.1	1.2	GO:0007620	copulation(GO:0007620)
0.1	5.0	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	24.0	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1	1.7	GO:0098926	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1	9.5	GO:0051896	regulation of protein kinase B signaling(GO:0051896)
0.1	0.4	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1	0.5	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.6	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	3.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	2.7	GO:0009311	oligosaccharide metabolic process(GO:0009311)
0.0	0.1	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0	0.6	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	1.1	GO:0042572	retinol metabolic process(GO:0042572)
0.0	1.2	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	1.6	GO:0030818	negative regulation of cAMP biosynthetic process(GO:0030818)
0.0	1.7	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	5.6	GO:0006338	chromatin remodeling(GO:0006338)
0.0	3.9	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	3.1	GO:0008380	RNA splicing(GO:0008380)
0.0	1.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	3.3	GO:0097191	extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.9	17.6	GO:0071756	IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
5.0	25.0	GO:0031523	Myb complex(GO:0031523)
2.9	11.4	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
2.5	10.1	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
2.4	16.8	GO:0005610	laminin-5 complex(GO:0005610)
2.3	13.9	GO:0097422	tubular endosome(GO:0097422)
2.1	10.7	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
1.8	12.3	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
1.7	11.9	GO:1990111	spermatoproteasome complex(GO:1990111)
1.5	15.4	GO:0005614	interstitial matrix(GO:0005614)
1.5	13.5	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
1.4	2.8	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.8	10.5	GO:0031209	SCAR complex(GO:0031209)
0.8	5.6	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.8	2.4	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.8	41.5	GO:0002102	podosome(GO:0002102)
0.8	19.8	GO:0005916	fascia adherens(GO:0005916)
0.7	8.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.7	12.9	GO:0033643	host cell part(GO:0033643)
0.7	3.5	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.7	7.5	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.6	5.7	GO:0042382	paraspeckles(GO:0042382)
0.6	6.9	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.6	10.3	GO:0000145	exocyst(GO:0000145)
0.6	12.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.5	6.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.5	16.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.4	5.4	GO:0030008	TRAPP complex(GO:0030008)
0.4	4.0	GO:0032039	integrator complex(GO:0032039)
0.3	3.7	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3	12.5	GO:0030125	clathrin vesicle coat(GO:0030125)
0.3	30.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.3	3.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.3	35.6	GO:0005882	intermediate filament(GO:0005882)
0.3	11.7	GO:0032420	stereocilium(GO:0032420)
0.3	56.5	GO:0072562	blood microparticle(GO:0072562)
0.2	3.0	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2	4.0	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2	10.9	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.2	7.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.2	0.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.2	18.3	GO:0016459	myosin complex(GO:0016459)
0.2	21.1	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.2	2.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	2.5	GO:0008091	spectrin(GO:0008091)
0.1	2.6	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.6	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1	10.7	GO:0035580	specific granule lumen(GO:0035580)
0.1	0.5	GO:0031905	early endosome lumen(GO:0031905)
0.1	2.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	8.6	GO:0005905	clathrin-coated pit(GO:0005905)
0.1	3.9	GO:0016235	aggresome(GO:0016235)
0.1	0.4	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1	6.0	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	73.2	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1	4.9	GO:0005902	microvillus(GO:0005902)
0.1	0.2	GO:0005760	gamma DNA polymerase complex(GO:0005760)
0.1	7.9	GO:0016605	PML body(GO:0016605)
0.1	19.1	GO:0010008	endosome membrane(GO:0010008)
0.1	22.4	GO:0016607	nuclear speck(GO:0016607)
0.1	7.8	GO:0005769	early endosome(GO:0005769)
0.0	0.8	GO:0046930	pore complex(GO:0046930)
0.0	14.3	GO:0031965	nuclear membrane(GO:0031965)
0.0	1.2	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.6	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	4.7	GO:0005795	Golgi stack(GO:0005795)
0.0	18.8	GO:0000139	Golgi membrane(GO:0000139)
0.0	2.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	1.2	GO:0055037	recycling endosome(GO:0055037)
0.0	3.0	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.0	2.7	GO:0005884	actin filament(GO:0005884)
0.0	2.6	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	2.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.5	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	5.2	GO:0016604	nuclear body(GO:0016604)
0.0	0.1	GO:0031251	PAN complex(GO:0031251)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.7	GO:0031526	brush border membrane(GO:0031526)
0.0	0.5	GO:0044216	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	6.2	GO:0005925	focal adhesion(GO:0005925)
0.0	1.7	GO:0031225	anchored component of membrane(GO:0031225)
0.0	14.7	GO:0005615	extracellular space(GO:0005615)
0.0	33.8	GO:0005654	nucleoplasm(GO:0005654)
0.0	3.1	GO:0030529	intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.1	35.6	GO:1990254	keratin filament binding(GO:1990254)
6.6	92.9	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
5.0	25.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
4.7	23.5	GO:0004920	interleukin-10 receptor activity(GO:0004920)
3.5	20.7	GO:0043023	ribosomal large subunit binding(GO:0043023)
3.1	18.7	GO:0043120	tumor necrosis factor binding(GO:0043120)
2.5	12.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
2.0	6.1	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
2.0	18.3	GO:0045545	syndecan binding(GO:0045545)
1.8	24.0	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
1.8	10.7	GO:1990763	arrestin family protein binding(GO:1990763)
1.5	21.8	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
1.3	4.0	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
1.3	11.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
1.2	5.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
1.2	10.9	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
1.1	7.5	GO:0042289	MHC class II protein binding(GO:0042289)
1.0	4.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.9	42.4	GO:0050699	WW domain binding(GO:0050699)
0.8	13.9	GO:0034452	dynactin binding(GO:0034452)
0.8	2.4	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.8	6.9	GO:1990226	histone methyltransferase binding(GO:1990226)
0.7	19.8	GO:0017166	vinculin binding(GO:0017166)
0.7	4.9	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.7	2.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.7	32.4	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.7	4.0	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.7	4.6	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.7	10.5	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.6	12.9	GO:0032036	myosin heavy chain binding(GO:0032036)
0.6	13.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.6	30.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.6	8.1	GO:0031386	protein tag(GO:0031386)
0.6	5.2	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.5	13.6	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.5	6.0	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.5	21.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.4	5.8	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.4	11.9	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4	8.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.4	2.7	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4	3.0	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.4	6.0	GO:0002162	dystroglycan binding(GO:0002162)
0.4	5.6	GO:0017160	Ral GTPase binding(GO:0017160)
0.4	2.6	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4	85.7	GO:0003823	antigen binding(GO:0003823)
0.3	6.0	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3	9.7	GO:0051059	NF-kappaB binding(GO:0051059)
0.3	14.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.3	0.5	GO:0032564	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.3	10.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.3	7.1	GO:0008301	DNA binding, bending(GO:0008301)
0.3	2.5	GO:0042731	PH domain binding(GO:0042731)
0.2	8.0	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2	1.7	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2	3.2	GO:0046527	glucosyltransferase activity(GO:0046527)
0.2	1.6	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.2	16.6	GO:0019003	GDP binding(GO:0019003)
0.2	0.6	GO:0032428	sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.2	6.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.2	2.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.2	10.2	GO:0005080	protein kinase C binding(GO:0005080)
0.2	3.9	GO:0070628	proteasome binding(GO:0070628)
0.2	2.6	GO:0001054	RNA polymerase I activity(GO:0001054)
0.1	2.5	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	1.2	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	2.3	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1	1.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	4.5	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	3.1	GO:0004707	MAP kinase activity(GO:0004707)
0.1	14.1	GO:0008013	beta-catenin binding(GO:0008013)
0.1	2.4	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.1	50.1	GO:0045296	cadherin binding(GO:0045296)
0.1	2.2	GO:0031491	nucleosome binding(GO:0031491)
0.1	1.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	1.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	2.8	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.1	4.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	3.8	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	3.0	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	2.5	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	0.9	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.1	0.8	GO:0051434	BH3 domain binding(GO:0051434)
0.1	5.9	GO:0008170	N-methyltransferase activity(GO:0008170)
0.1	1.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	3.2	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1	2.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.7	GO:0005542	folic acid binding(GO:0005542)
0.0	0.4	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.8	GO:0031701	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	6.5	GO:0051015	actin filament binding(GO:0051015)
0.0	0.6	GO:0004985	opioid receptor activity(GO:0004985)
0.0	1.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.5	GO:0015926	glucosidase activity(GO:0015926)
0.0	0.9	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	9.3	GO:0030246	carbohydrate binding(GO:0030246)
0.0	4.3	GO:0002020	protease binding(GO:0002020)
0.0	3.7	GO:0005057	receptor signaling protein activity(GO:0005057)
0.0	1.8	GO:0050661	NADP binding(GO:0050661)
0.0	3.2	GO:0005179	hormone activity(GO:0005179)
0.0	0.5	GO:0050811	GABA receptor binding(GO:0050811)
0.0	1.2	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.5	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	6.0	GO:0003924	GTPase activity(GO:0003924)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.5	GO:0001848	complement binding(GO:0001848)
0.0	28.8	GO:0003723	RNA binding(GO:0003723)
0.0	2.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	128.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
2.1	23.4	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
1.1	42.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.9	16.8	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.8	49.0	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.6	35.6	PID AURORA B PATHWAY	Aurora B signaling
0.6	38.9	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.6	5.9	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.5	16.8	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.5	10.9	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.5	11.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.3	9.8	PID IL27 PATHWAY	IL27-mediated signaling events
0.3	9.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.3	23.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.2	16.9	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	16.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2	15.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.2	9.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.2	6.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2	1.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	3.8	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.2	4.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	8.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	19.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	13.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	2.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	7.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	6.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	1.0	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	2.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	1.2	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	1.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	116.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
1.9	42.6	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
1.4	9.7	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
1.2	35.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.9	32.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.6	19.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.6	11.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5	9.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5	9.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.5	24.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.5	10.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.4	12.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.4	27.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.3	10.7	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.3	18.8	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.3	10.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3	5.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.2	3.8	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.2	8.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.2	8.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	9.5	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.2	5.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2	8.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.2	2.7	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1	18.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	2.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	2.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	2.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	2.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	4.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.1	7.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	2.2	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.1	5.9	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	1.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	0.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	7.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	3.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	3.2	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.0	0.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	2.6	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.8	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.9	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	2.8	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	1.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism

Results for REL

Z-value: 1.94

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Transcription factors associated with REL

Activity-expression correlation:

Activity profile of REL motif

Sorted Z-values of REL motif

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: