avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
RELA Links Ensembl NCBI GeneCards UniProt	ENSG00000173039.19	RELA

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RELA	hg38_v1_chr11_-_65663083_65663108	0.55	2.0e-18	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr6_+_137867241 Show fit	38.36	ENST00000612899.5 ENST00000420009.5	TNFAIP3 Links Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chr6_+_137867414 Show fit	37.21	ENST00000237289.8 ENST00000433680.1	TNFAIP3 Links Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chr14_-_35404650 Show fit	33.04	ENST00000553342.1 ENST00000557140.5 ENST00000216797.10	NFKBIA Links Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor alpha
chr17_-_4949037 Show fit	21.95	ENST00000572383.1	PFN1 Links Ensembl NCBI GeneCards UniProt Show fit	profilin 1
chr6_+_29723421 Show fit	21.13	ENST00000259951.12 ENST00000434407.6	HLA-F Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, F
chr6_+_29723340 Show fit	21.02	ENST00000334668.8	HLA-F Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, F
chr6_+_32637419 Show fit	18.75	ENST00000374949.2	HLA-DQA1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ alpha 1
chr5_-_151087131 Show fit	18.35	ENST00000315050.11 ENST00000523338.5 ENST00000522100.5	TNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	TNFAIP3 interacting protein 1
chr6_-_31582415 Show fit	17.82	ENST00000429299.3 ENST00000446745.2	LTB Links Ensembl NCBI GeneCards UniProt Show fit	lymphotoxin beta
chr22_-_37244237 Show fit	17.17	ENST00000401529.3 ENST00000249071.11	RAC2 Links Ensembl NCBI GeneCards UniProt Show fit	Rac family small GTPase 2
chr5_-_150412743 Show fit	17.01	ENST00000353334.11 ENST00000009530.12 ENST00000377795.7	CD74 Links Ensembl NCBI GeneCards UniProt Show fit	CD74 molecule
chr11_-_58578096 Show fit	16.41	ENST00000528954.5 ENST00000528489.1	LPXN Links Ensembl NCBI GeneCards UniProt Show fit	leupaxin
chr11_+_102317450 Show fit	15.67	ENST00000615299.4 ENST00000527309.2 ENST00000526421.6 ENST00000263464.9	BIRC3 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr11_+_102317542 Show fit	15.66	ENST00000532808.5	BIRC3 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr5_-_151080978 Show fit	14.82	ENST00000520931.5 ENST00000521591.6 ENST00000520695.5 ENST00000610535.5 ENST00000518977.5 ENST00000389378.6 ENST00000610874.4	TNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	TNFAIP3 interacting protein 1
chr6_-_30744537 Show fit	14.01	ENST00000259874.6 ENST00000376377.2	IER3 Links Ensembl NCBI GeneCards UniProt Show fit	immediate early response 3
chr6_+_32637396 Show fit	13.02	ENST00000395363.5 ENST00000496318.5 ENST00000343139.11	HLA-DQA1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ alpha 1
chr17_+_78168565 Show fit	12.88	ENST00000225777.8 ENST00000585591.5 ENST00000589711.1 ENST00000588282.5 ENST00000589168.1	SYNGR2 Links Ensembl NCBI GeneCards UniProt Show fit	synaptogyrin 2
chr17_+_78169127 Show fit	12.79	ENST00000590201.1	SYNGR2 Links Ensembl NCBI GeneCards UniProt Show fit	synaptogyrin 2
chr12_-_9760893 Show fit	12.65	ENST00000228434.7 ENST00000536709.1	CD69 Links Ensembl NCBI GeneCards UniProt Show fit	CD69 molecule
chr4_+_102501298 Show fit	11.29	ENST00000394820.8 ENST00000226574.9 ENST00000511926.5 ENST00000507079.5	NFKB1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 1
chr4_+_73869385 Show fit	11.18	ENST00000395761.4	CXCL1 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 1
chr16_+_50742110 Show fit	11.14	ENST00000566679.6 ENST00000564634.5 ENST00000398568.6	CYLD Links Ensembl NCBI GeneCards UniProt Show fit	CYLD lysine 63 deubiquitinase
chr1_-_159925496 Show fit	10.89	ENST00000368097.9	TAGLN2 Links Ensembl NCBI GeneCards UniProt Show fit	transgelin 2
chr16_+_50742037 Show fit	10.60	ENST00000569418.5	CYLD Links Ensembl NCBI GeneCards UniProt Show fit	CYLD lysine 63 deubiquitinase
chr10_+_102394488 Show fit	10.45	ENST00000369966.8	NFKB2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 2
chr4_-_74099187 Show fit	10.43	ENST00000508487.3	CXCL2 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 2
chr18_+_3252267 Show fit	10.39	ENST00000536605.1 ENST00000580887.5	MYL12A Links Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12A
chr22_-_37244417 Show fit	10.24	ENST00000405484.5 ENST00000441619.5 ENST00000406508.5	RAC2 Links Ensembl NCBI GeneCards UniProt Show fit	Rac family small GTPase 2
chr11_+_102317492 Show fit	10.23	ENST00000673846.1	BIRC3 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr21_+_33403466 Show fit	9.96	ENST00000405436.5	IFNGR2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr17_+_42288429 Show fit	9.87	ENST00000676631.1 ENST00000677893.1	STAT5A Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr4_-_102828022 Show fit	9.70	ENST00000502690.5	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr1_-_64966488 Show fit	9.69	ENST00000342505.5 ENST00000673254.1	JAK1 Links Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 1
chr1_+_44405247 Show fit	9.65	ENST00000361799.7 ENST00000372247.6	RNF220 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 220
chr4_-_102828048 Show fit	9.64	ENST00000508249.1	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr6_-_32853618 Show fit	9.62	ENST00000354258.5	TAP1 Links Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP binding cassette subfamily B member
chr1_-_64966284 Show fit	9.48	ENST00000671929.1 ENST00000673046.1 ENST00000672247.1	JAK1 Links Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 1
chr4_-_40629842 Show fit	9.37	ENST00000295971.12	RBM47 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 47
chr17_+_16415553 Show fit	9.27	ENST00000338560.12	TRPV2 Links Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily V member 2
chr6_-_32853813 Show fit	9.27	ENST00000643049.2	TAP1 Links Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP binding cassette subfamily B member
chr4_-_184474518 Show fit	9.17	ENST00000393593.8	IRF2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 2
chr1_-_1891056 Show fit	8.98	ENST00000378609.9 ENST00000610897.4 ENST00000615252.4	GNB1 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit beta 1
chr21_+_33403391 Show fit	8.86	ENST00000290219.11 ENST00000381995.5	IFNGR2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr11_-_73142308 Show fit	8.60	ENST00000409418.9	FCHSD2 Links Ensembl NCBI GeneCards UniProt Show fit	FCH and double SH3 domains 2
chr15_+_52019206 Show fit	8.53	ENST00000681888.1 ENST00000261845.7 ENST00000680066.1 ENST00000680777.1 ENST00000680652.1	MAPK6 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 6
chr7_-_93890744 Show fit	8.45	ENST00000650573.1 ENST00000222543.11 ENST00000649913.1 ENST00000647793.1	TFPI2 Links Ensembl NCBI GeneCards UniProt Show fit	tissue factor pathway inhibitor 2
chr1_+_44405164 Show fit	8.42	ENST00000355387.6	RNF220 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 220
chr1_+_155687946 Show fit	8.35	ENST00000471642.6 ENST00000471214.5	DAP3 Links Ensembl NCBI GeneCards UniProt Show fit	death associated protein 3
chr8_-_102655707 Show fit	8.17	ENST00000285407.11	KLF10 Links Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 10
chr14_+_103123452 Show fit	8.15	ENST00000558056.1 ENST00000560869.6	TNFAIP2 Links Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 2
chr16_-_28211476 Show fit	8.04	ENST00000569951.1 ENST00000565698.5	XPO6 Links Ensembl NCBI GeneCards UniProt Show fit	exportin 6
chr3_+_53161241 Show fit	7.99	ENST00000477794.2 ENST00000650739.1	PRKCD Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C delta
chr6_-_32668368 Show fit	7.85	ENST00000399084.5	HLA-DQB1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ beta 1
chr12_+_6946468 Show fit	7.80	ENST00000543115.5 ENST00000399448.5	PTPN6 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr3_+_53161120 Show fit	7.64	ENST00000394729.6 ENST00000330452.8 ENST00000652449.1	PRKCD Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C delta
chr1_-_209652329 Show fit	7.40	ENST00000367030.7 ENST00000356082.9	LAMB3 Links Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 3
chr17_+_42288464 Show fit	7.38	ENST00000590726.7 ENST00000678903.1 ENST00000590949.6 ENST00000676585.1 ENST00000588868.5	STAT5A Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr11_-_73142032 Show fit	7.19	ENST00000311172.11 ENST00000409314.5	FCHSD2 Links Ensembl NCBI GeneCards UniProt Show fit	FCH and double SH3 domains 2
chr7_+_143381561 Show fit	7.06	ENST00000354434.8	ZYX Links Ensembl NCBI GeneCards UniProt Show fit	zyxin
chr20_-_2470749 Show fit	7.02	ENST00000381342.7 ENST00000438552.6	SNRPB Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptides B and B1
chr2_-_89143133 Show fit	6.98	ENST00000492167.1	IGKV3-20 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-20
chr22_-_37149900 Show fit	6.95	ENST00000216223.10	IL2RB Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 2 receptor subunit beta
chr19_+_2476118 Show fit	6.91	ENST00000215631.9 ENST00000587345.1	GADD45B Links Ensembl NCBI GeneCards UniProt Show fit	growth arrest and DNA damage inducible beta
chr20_+_1135217 Show fit	6.90	ENST00000381898.5	PSMF1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome inhibitor subunit 1
chr20_+_1135178 Show fit	6.86	ENST00000435720.5	PSMF1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome inhibitor subunit 1
chr10_+_102395693 Show fit	6.71	ENST00000652277.1 ENST00000189444.11 ENST00000661543.1	NFKB2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 2
chr1_+_26543106 Show fit	6.67	ENST00000530003.5	RPS6KA1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A1
chr3_+_157436842 Show fit	6.63	ENST00000295927.4	PTX3 Links Ensembl NCBI GeneCards UniProt Show fit	pentraxin 3
chr3_-_182980531 Show fit	6.58	ENST00000292782.9 ENST00000632685.1	DCUN1D1 Links Ensembl NCBI GeneCards UniProt Show fit	defective in cullin neddylation 1 domain containing 1
chr10_-_43408787 Show fit	6.57	ENST00000356053.7	HNRNPF Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr2_+_227813834 Show fit	6.25	ENST00000358813.5 ENST00000409189.7	CCL20 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 20
chr17_-_7687427 Show fit	6.18	ENST00000514944.5 ENST00000503591.1 ENST00000610292.4 ENST00000420246.6 ENST00000455263.6 ENST00000610538.4 ENST00000622645.4 ENST00000445888.6 ENST00000619485.4 ENST00000509690.5 ENST00000604348.5 ENST00000269305.9 ENST00000620739.4	TP53 Links Ensembl NCBI GeneCards UniProt Show fit	tumor protein p53
chrX_-_20266606 Show fit	6.12	ENST00000643085.1 ENST00000645270.1 ENST00000644368.1	RPS6KA3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr1_-_31938302 Show fit	6.08	ENST00000647444.2	PTP4A2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A2
chr16_-_28211908 Show fit	6.07	ENST00000566073.1 ENST00000304658.10	XPO6 Links Ensembl NCBI GeneCards UniProt Show fit	exportin 6
chr2_+_161136901 Show fit	5.94	ENST00000259075.6 ENST00000432002.5	TANK Links Ensembl NCBI GeneCards UniProt Show fit	TRAF family member associated NFKB activator
chr17_-_35880350 Show fit	5.73	ENST00000605140.6 ENST00000651122.1 ENST00000603197.6	CCL5 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 5
chr4_-_102828159 Show fit	5.73	ENST00000394803.9	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr19_-_49640092 Show fit	5.65	ENST00000246792.4	RRAS Links Ensembl NCBI GeneCards UniProt Show fit	RAS related
chr14_-_68979436 Show fit	5.64	ENST00000193403.10	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr7_+_143381286 Show fit	5.54	ENST00000449630.5 ENST00000322764.10 ENST00000457235.5	ZYX Links Ensembl NCBI GeneCards UniProt Show fit	zyxin
chr1_-_186680411 Show fit	5.51	ENST00000367468.10	PTGS2 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 2
chr11_+_121452291 Show fit	5.46	ENST00000260197.12	SORL1 Links Ensembl NCBI GeneCards UniProt Show fit	sortilin related receptor 1
chr6_+_144150492 Show fit	5.43	ENST00000367568.5	STX11 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 11
chr4_-_102827948 Show fit	5.43	ENST00000394804.6 ENST00000394801.8	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr7_-_16804987 Show fit	5.40	ENST00000401412.5 ENST00000419304.7	AGR2 Links Ensembl NCBI GeneCards UniProt Show fit	anterior gradient 2, protein disulphide isomerase family member
chr11_-_6612141 Show fit	5.33	ENST00000527248.2 ENST00000299424.9	TAF10 Links Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 10
chr5_+_177592182 Show fit	5.16	ENST00000332598.7	TMED9 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane p24 trafficking protein 9
chr7_+_22727147 Show fit	5.16	ENST00000426291.5 ENST00000401651.5 ENST00000258743.10 ENST00000407492.5 ENST00000401630.7 ENST00000406575.1	IL6 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 6
chr2_+_161308407 Show fit	5.07	ENST00000409682.8	PSMD14 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 14
chr7_-_101237791 Show fit	4.99	ENST00000308344.10	CLDN15 Links Ensembl NCBI GeneCards UniProt Show fit	claudin 15
chr11_-_3840942 Show fit	4.96	ENST00000351018.5	RHOG Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member G
chr11_-_57530714 Show fit	4.96	ENST00000525158.1 ENST00000257245.9 ENST00000525587.1	TIMM10 Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 10
chr7_-_101237827 Show fit	4.90	ENST00000611078.4	CLDN15 Links Ensembl NCBI GeneCards UniProt Show fit	claudin 15
chr1_-_36149450 Show fit	4.90	ENST00000373163.5	TRAPPC3 Links Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3
chr9_-_125189721 Show fit	4.73	ENST00000456642.1 ENST00000373547.9 ENST00000415905.5 ENST00000451402.5	PPP6C Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 6 catalytic subunit
chr2_+_162318884 Show fit	4.71	ENST00000446271.5 ENST00000429691.6	GCA Links Ensembl NCBI GeneCards UniProt Show fit	grancalcin
chr14_+_64503943 Show fit	4.64	ENST00000556965.1 ENST00000554015.5	ZBTB1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 1
chr12_-_57110284 Show fit	4.62	ENST00000543873.6 ENST00000554663.5 ENST00000557635.5	STAT6 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 6
chr3_+_172039556 Show fit	4.61	ENST00000415807.7 ENST00000421757.5	FNDC3B Links Ensembl NCBI GeneCards UniProt Show fit	fibronectin type III domain containing 3B
chr3_-_177197210 Show fit	4.59	ENST00000431421.5 ENST00000422066.5 ENST00000413084.5 ENST00000673974.1 ENST00000422442.6	TBL1XR1 Links Ensembl NCBI GeneCards UniProt Show fit	TBL1X receptor 1
chr10_-_124092445 Show fit	4.52	ENST00000346248.7	CHST15 Links Ensembl NCBI GeneCards UniProt Show fit	carbohydrate sulfotransferase 15
chr4_-_102827723 Show fit	4.50	ENST00000349311.12	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr1_-_205775449 Show fit	4.45	ENST00000235932.8 ENST00000437324.6 ENST00000414729.1 ENST00000367139.8	RAB29 Links Ensembl NCBI GeneCards UniProt Show fit	RAB29, member RAS oncogene family
chr20_-_4815100 Show fit	4.35	ENST00000379376.2	RASSF2 Links Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 2
chr14_-_68979251 Show fit	4.34	ENST00000438964.6 ENST00000679147.1	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr3_-_177197429 Show fit	4.28	ENST00000457928.7	TBL1XR1 Links Ensembl NCBI GeneCards UniProt Show fit	TBL1X receptor 1
chr22_-_27919199 Show fit	4.28	ENST00000634017.1 ENST00000436663.1 ENST00000320996.14 ENST00000335272.10 ENST00000455418.7	PITPNB Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol transfer protein beta
chr17_-_63699730 Show fit	4.23	ENST00000578061.5	LIMD2 Links Ensembl NCBI GeneCards UniProt Show fit	LIM domain containing 2
chr2_-_191020960 Show fit	4.15	ENST00000432058.1	STAT1 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 1
chr1_-_209651291 Show fit	4.14	ENST00000391911.5 ENST00000415782.1	LAMB3 Links Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 3
chr17_+_21288029 Show fit	4.12	ENST00000526076.6 ENST00000361818.9 ENST00000316920.10	MAP2K3 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase 3
chr14_-_68979076 Show fit	4.11	ENST00000538545.6 ENST00000684639.1	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr4_+_41612702 Show fit	4.07	ENST00000509277.5	LIMCH1 Links Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr12_-_6607334 Show fit	4.00	ENST00000645645.1 ENST00000357008.7 ENST00000544484.6 ENST00000544040.7	CHD4 Links Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 4
chr2_-_43226594 Show fit	3.95	ENST00000282388.4	ZFP36L2 Links Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein like 2
chrX_-_15854743 Show fit	3.87	ENST00000450644.2	AP1S2 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit sigma 2
chr19_+_45001430 Show fit	3.85	ENST00000625761.2 ENST00000505236.1 ENST00000221452.13	RELB Links Ensembl NCBI GeneCards UniProt Show fit	RELB proto-oncogene, NF-kB subunit
chrX_-_132218124 Show fit	3.83	ENST00000342983.6	RAP2C Links Ensembl NCBI GeneCards UniProt Show fit	RAP2C, member of RAS oncogene family
chrX_-_132219439 Show fit	3.80	ENST00000370874.2	RAP2C Links Ensembl NCBI GeneCards UniProt Show fit	RAP2C, member of RAS oncogene family
chr12_-_6607397 Show fit	3.75	ENST00000645005.1 ENST00000646806.1	CHD4 Links Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 4
chr13_-_51453015 Show fit	3.69	ENST00000442263.4 ENST00000311234.9	INTS6 Links Ensembl NCBI GeneCards UniProt Show fit	integrator complex subunit 6
chrX_-_132219473 Show fit	3.68	ENST00000620646.4	RAP2C Links Ensembl NCBI GeneCards UniProt Show fit	RAP2C, member of RAS oncogene family
chr6_+_292050 Show fit	3.61	ENST00000344450.9	DUSP22 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 22
chr3_+_184315347 Show fit	3.58	ENST00000424196.5	EIF4G1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4 gamma 1
chr4_+_139301478 Show fit	3.56	ENST00000296543.10 ENST00000398947.1	NAA15 Links Ensembl NCBI GeneCards UniProt Show fit	N-alpha-acetyltransferase 15, NatA auxiliary subunit
chr15_-_51622613 Show fit	3.54	ENST00000543779.6 ENST00000449909.7	DMXL2 Links Ensembl NCBI GeneCards UniProt Show fit	Dmx like 2
chr10_+_22316445 Show fit	3.43	ENST00000448361.5	COMMD3 Links Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 3
chr15_-_51622738 Show fit	3.42	ENST00000560891.6	DMXL2 Links Ensembl NCBI GeneCards UniProt Show fit	Dmx like 2
chr19_-_6591103 Show fit	3.39	ENST00000423145.7 ENST00000245903.4	CD70 Links Ensembl NCBI GeneCards UniProt Show fit	CD70 molecule
chr19_+_4229502 Show fit	3.38	ENST00000221847.6	EBI3 Links Ensembl NCBI GeneCards UniProt Show fit	Epstein-Barr virus induced 3
chr19_-_7702124 Show fit	3.36	ENST00000597921.6	FCER2 Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgE receptor II
chr2_+_236569817 Show fit	3.36	ENST00000272928.4	ACKR3 Links Ensembl NCBI GeneCards UniProt Show fit	atypical chemokine receptor 3
chr1_-_112707056 Show fit	3.34	ENST00000369633.6 ENST00000425265.6 ENST00000369632.6 ENST00000436685.6 ENST00000484054.3 ENST00000369636.6 ENST00000369637.5 ENST00000339083.12 ENST00000285735.6 ENST00000369638.6	RHOC Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member C
chr1_-_205775182 Show fit	3.33	ENST00000446390.6	RAB29 Links Ensembl NCBI GeneCards UniProt Show fit	RAB29, member RAS oncogene family
chr19_-_7702139 Show fit	3.24	ENST00000346664.9	FCER2 Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgE receptor II
chr5_+_112976757 Show fit	3.22	ENST00000389063.3	DCP2 Links Ensembl NCBI GeneCards UniProt Show fit	decapping mRNA 2
chr1_-_36149464 Show fit	3.13	ENST00000373166.8 ENST00000373159.1 ENST00000373162.5 ENST00000616074.4 ENST00000616395.4	TRAPPC3 Links Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3
chr19_+_41877267 Show fit	3.12	ENST00000221972.8 ENST00000597454.1 ENST00000444740.2	CD79A Links Ensembl NCBI GeneCards UniProt Show fit	CD79a molecule
chr3_+_52198086 Show fit	3.09	ENST00000469224.5 ENST00000394965.6	ALAS1 Links Ensembl NCBI GeneCards UniProt Show fit	5'-aminolevulinate synthase 1
chr1_+_203305510 Show fit	3.08	ENST00000290551.5	BTG2 Links Ensembl NCBI GeneCards UniProt Show fit	BTG anti-proliferation factor 2
chr3_+_52198113 Show fit	3.07	ENST00000310271.6	ALAS1 Links Ensembl NCBI GeneCards UniProt Show fit	5'-aminolevulinate synthase 1
chr3_+_52198152 Show fit	2.99	ENST00000484952.6	ALAS1 Links Ensembl NCBI GeneCards UniProt Show fit	5'-aminolevulinate synthase 1
chr6_-_29559724 Show fit	2.96	ENST00000377050.5	UBD Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin D
chr20_-_37527891 Show fit	2.93	ENST00000414542.6	BLCAP Links Ensembl NCBI GeneCards UniProt Show fit	BLCAP apoptosis inducing factor
chr2_+_161160420 Show fit	2.92	ENST00000392749.7 ENST00000405852.5	TANK Links Ensembl NCBI GeneCards UniProt Show fit	TRAF family member associated NFKB activator
chr10_+_22316375 Show fit	2.91	ENST00000376836.8 ENST00000456711.5 ENST00000444869.5 ENST00000475460.6 ENST00000602390.5 ENST00000489125.2	COMMD3 Links Ensembl NCBI GeneCards UniProt Show fit COMMD3-BMI1 Links Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 3 COMMD3-BMI1 readthrough
chr5_+_140401808 Show fit	2.90	ENST00000616482.4 ENST00000297183.10 ENST00000360839.7 ENST00000421134.5 ENST00000394723.7 ENST00000511151.5	ANKHD1 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and KH domain containing 1
chrX_-_48897747 Show fit	2.87	ENST00000490755.2 ENST00000465150.6 ENST00000495490.6	TIMM17B Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 17B
chr15_+_85380565 Show fit	2.86	ENST00000559362.5 ENST00000394518.7	AKAP13 Links Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 13
chr14_-_68979274 Show fit	2.80	ENST00000394419.9	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr3_+_5122276 Show fit	2.77	ENST00000256496.8 ENST00000419534.2	ARL8B Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 8B
chr6_+_31572279 Show fit	2.72	ENST00000418386.3	LTA Links Ensembl NCBI GeneCards UniProt Show fit	lymphotoxin alpha
chr19_+_41219177 Show fit	2.70	ENST00000301178.9	AXL Links Ensembl NCBI GeneCards UniProt Show fit	AXL receptor tyrosine kinase
chr11_+_10455292 Show fit	2.68	ENST00000396553.6	AMPD3 Links Ensembl NCBI GeneCards UniProt Show fit	adenosine monophosphate deaminase 3
chr14_-_68979314 Show fit	2.67	ENST00000684713.1 ENST00000683198.1 ENST00000684598.1 ENST00000682331.1 ENST00000682291.1 ENST00000683342.1	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr19_+_41860236 Show fit	2.65	ENST00000601492.5 ENST00000600467.6 ENST00000598742.6 ENST00000221975.6 ENST00000598261.2	RPS19 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S19
chr7_+_17298642 Show fit	2.64	ENST00000242057.9	AHR Links Ensembl NCBI GeneCards UniProt Show fit	aryl hydrocarbon receptor
chr15_-_51622798 Show fit	2.63	ENST00000251076.9	DMXL2 Links Ensembl NCBI GeneCards UniProt Show fit	Dmx like 2
chr1_+_7961894 Show fit	2.60	ENST00000377491.5 ENST00000377488.5	PARK7 Links Ensembl NCBI GeneCards UniProt Show fit	Parkinsonism associated deglycase
chr1_-_155688294 Show fit	2.59	ENST00000311573.9	YY1AP1 Links Ensembl NCBI GeneCards UniProt Show fit	YY1 associated protein 1
chr4_-_73998669 Show fit	2.59	ENST00000296027.5	CXCL5 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 5
chr6_-_73520985 Show fit	2.58	ENST00000676710.1 ENST00000316292.13 ENST00000309268.11 ENST00000610520.5 ENST00000678515.1 ENST00000678703.1	EEF1A1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 alpha 1
chr7_+_101817601 Show fit	2.54	ENST00000292535.12 ENST00000546411.7 ENST00000549414.6 ENST00000550008.6 ENST00000556210.1	CUX1 Links Ensembl NCBI GeneCards UniProt Show fit	cut like homeobox 1
chr16_+_1309136 Show fit	2.47	ENST00000325437.9	UBE2I Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 I
chr15_+_43792305 Show fit	2.46	ENST00000249786.9 ENST00000409960.6 ENST00000409646.5 ENST00000339624.9 ENST00000409291.5 ENST00000402131.5 ENST00000403425.5 ENST00000430901.1	SERF2 Links Ensembl NCBI GeneCards UniProt Show fit	small EDRK-rich factor 2
chr2_-_135985568 Show fit	2.38	ENST00000264161.9	DARS1 Links Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 1
chr1_-_93614091 Show fit	2.36	ENST00000370247.7	BCAR3 Links Ensembl NCBI GeneCards UniProt Show fit	BCAR3 adaptor protein, NSP family member
chr20_-_31722533 Show fit	2.35	ENST00000677194.1 ENST00000434194.2 ENST00000376062.6	BCL2L1 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2 like 1
chr18_-_12884151 Show fit	2.33	ENST00000591115.5 ENST00000309660.10 ENST00000353319.8 ENST00000327283.7	PTPN2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 2
chr20_-_37527723 Show fit	2.32	ENST00000397135.1 ENST00000397137.5	BLCAP Links Ensembl NCBI GeneCards UniProt Show fit	BLCAP apoptosis inducing factor
chr6_+_135181323 Show fit	2.32	ENST00000367814.8	MYB Links Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene, transcription factor
chr5_+_140401860 Show fit	2.28	ENST00000532219.5 ENST00000394722.7	ANKHD1-EIF4EBP3 Links Ensembl NCBI GeneCards UniProt Show fit ANKHD1 Links Ensembl NCBI GeneCards UniProt Show fit	ANKHD1-EIF4EBP3 readthrough ankyrin repeat and KH domain containing 1
chr3_+_9397831 Show fit	2.27	ENST00000682536.1 ENST00000406341.5	SETD5 Links Ensembl NCBI GeneCards UniProt Show fit	SET domain containing 5
chr7_-_24757926 Show fit	2.26	ENST00000342947.9 ENST00000419307.6	GSDME Links Ensembl NCBI GeneCards UniProt Show fit	gasdermin E
chr18_+_34710307 Show fit	2.24	ENST00000679796.1	DTNA Links Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin alpha
chr4_-_74038681 Show fit	2.22	ENST00000296026.4	CXCL3 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 3
chr22_+_40951364 Show fit	2.16	ENST00000216225.9	RBX1 Links Ensembl NCBI GeneCards UniProt Show fit	ring-box 1
chr11_-_128522189 Show fit	2.12	ENST00000526145.6	ETS1 Links Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr16_+_50696999 Show fit	2.09	ENST00000300589.6	NOD2 Links Ensembl NCBI GeneCards UniProt Show fit	nucleotide binding oligomerization domain containing 2
chr2_+_60881515 Show fit	2.08	ENST00000295025.12	REL Links Ensembl NCBI GeneCards UniProt Show fit	REL proto-oncogene, NF-kB subunit
chr17_-_7251691 Show fit	2.07	ENST00000574322.6	CTDNEP1 Links Ensembl NCBI GeneCards UniProt Show fit	CTD nuclear envelope phosphatase 1
chr2_+_207529731 Show fit	2.06	ENST00000430624.5	CREB1 Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 1
chr1_-_155978144 Show fit	2.03	ENST00000313695.11 ENST00000497907.5	ARHGEF2 Links Ensembl NCBI GeneCards UniProt Show fit	Rho/Rac guanine nucleotide exchange factor 2
chr19_-_4831689 Show fit	2.02	ENST00000248244.6	TICAM1 Links Ensembl NCBI GeneCards UniProt Show fit	toll like receptor adaptor molecule 1
chr14_+_75522531 Show fit	2.00	ENST00000555504.1	BATF Links Ensembl NCBI GeneCards UniProt Show fit	basic leucine zipper ATF-like transcription factor
chr3_+_9397602 Show fit	2.00	ENST00000402198.7	SETD5 Links Ensembl NCBI GeneCards UniProt Show fit	SET domain containing 5
chr19_+_10271093 Show fit	1.96	ENST00000423829.2 ENST00000588645.1 ENST00000264832.8	ICAM1 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 1
chr17_+_7834200 Show fit	1.95	ENST00000448097.7	KDM6B Links Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 6B
chr7_-_24757413 Show fit	1.90	ENST00000645220.1 ENST00000409970.6	GSDME Links Ensembl NCBI GeneCards UniProt Show fit	gasdermin E
chr15_+_57592003 Show fit	1.89	ENST00000587652.5 ENST00000649429.1 ENST00000380568.7 ENST00000380565.8	GCOM1 Links Ensembl NCBI GeneCards UniProt Show fit MYZAP Links Ensembl NCBI GeneCards UniProt Show fit	GRINL1A complex locus 1 myocardial zonula adherens protein
chr14_+_75522427 Show fit	1.89	ENST00000286639.8	BATF Links Ensembl NCBI GeneCards UniProt Show fit	basic leucine zipper ATF-like transcription factor
chr14_-_21383989 Show fit	1.88	ENST00000216297.7	SUPT16H Links Ensembl NCBI GeneCards UniProt Show fit	SPT16 homolog, facilitates chromatin remodeling subunit
chr2_+_60881553 Show fit	1.86	ENST00000394479.4	REL Links Ensembl NCBI GeneCards UniProt Show fit	REL proto-oncogene, NF-kB subunit
chr1_+_100719734 Show fit	1.83	ENST00000370119.8 ENST00000294728.7 ENST00000347652.6 ENST00000370115.1	VCAM1 Links Ensembl NCBI GeneCards UniProt Show fit	vascular cell adhesion molecule 1
chr12_-_54259531 Show fit	1.77	ENST00000550411.5 ENST00000439541.6	CBX5 Links Ensembl NCBI GeneCards UniProt Show fit	chromobox 5
chr12_-_56333693 Show fit	1.76	ENST00000425394.7 ENST00000548043.5	PAN2 Links Ensembl NCBI GeneCards UniProt Show fit	poly(A) specific ribonuclease subunit PAN2
chrX_-_120575783 Show fit	1.76	ENST00000680673.1	CUL4B Links Ensembl NCBI GeneCards UniProt Show fit	cullin 4B
chr19_-_11577632 Show fit	1.71	ENST00000590420.1 ENST00000648477.1	ACP5 Links Ensembl NCBI GeneCards UniProt Show fit	acid phosphatase 5, tartrate resistant

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
25.2	75.6	GO:0034147	regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
8.3	33.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
6.8	20.5	GO:1990108	protein linear deubiquitination(GO:1990108)
6.3	18.9	GO:0046967	cytosol to ER transport(GO:0046967)
5.7	17.0	GO:0035691	macrophage migration inhibitory factor signaling pathway(GO:0035691)
5.2	15.6	GO:2000753	regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
4.3	17.2	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
4.2	42.2	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
3.8	42.0	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
3.5	41.6	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
3.0	24.2	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
2.9	26.2	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
2.6	29.1	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
2.5	27.4	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
2.5	17.2	GO:0000255	allantoin metabolic process(GO:0000255)
2.2	6.6	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
2.1	6.2	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
2.1	6.2	GO:0051097	negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
1.8	5.5	GO:1902769	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.7	22.0	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
1.6	9.4	GO:0016554	cytidine to uridine editing(GO:0016554)
1.5	4.6	GO:2000174	regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
1.5	10.7	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
1.5	10.3	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
1.4	4.3	GO:1903093	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of ubiquitin-specific protease activity(GO:2000152) negative regulation of ubiquitin-specific protease activity(GO:2000157)
1.4	5.7	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.4	4.2	GO:0046725	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
1.4	5.5	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.4	5.4	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
1.3	5.2	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.3	5.2	GO:2000364	hepatic immune response(GO:0002384) response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
1.3	2.5	GO:2000669	negative regulation of dendritic cell apoptotic process(GO:2000669)
1.2	4.6	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
1.1	7.8	GO:0072553	terminal button organization(GO:0072553)
1.0	2.1	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
1.0	8.9	GO:0060613	fat pad development(GO:0060613)
0.9	19.6	GO:0051639	actin filament network formation(GO:0051639)
0.9	3.6	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.9	2.6	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.8	8.1	GO:0051601	exocyst localization(GO:0051601)
0.7	35.0	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.7	2.9	GO:1904550	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.7	4.2	GO:0030578	PML body organization(GO:0030578)
0.7	2.0	GO:0045350	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.7	3.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.6	3.8	GO:0022614	membrane to membrane docking(GO:0022614)
0.6	18.8	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.6	2.5	GO:1903182	regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.6	19.7	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.6	9.6	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.6	7.8	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.6	3.0	GO:0070842	aggresome assembly(GO:0070842)
0.6	3.9	GO:1904628	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.6	5.0	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.5	8.7	GO:0045116	protein neddylation(GO:0045116)
0.5	9.5	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.5	2.6	GO:0032621	interleukin-18 production(GO:0032621)
0.5	11.3	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.5	3.6	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.5	1.5	GO:0033386	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.5	48.9	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.5	9.2	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.5	9.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.5	4.1	GO:0035897	proteolysis in other organism(GO:0035897)
0.4	2.7	GO:0006196	AMP catabolic process(GO:0006196)
0.4	4.4	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4	3.8	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.4	11.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.4	18.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.4	3.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3	1.7	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.3	3.4	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.3	2.4	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.3	16.6	GO:0051865	protein autoubiquitination(GO:0051865)
0.3	6.9	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.3	5.4	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.3	5.3	GO:0070365	hepatocyte differentiation(GO:0070365)
0.3	1.5	GO:0050915	sensory perception of sour taste(GO:0050915)
0.3	0.8	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3	0.6	GO:0070343	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.3	2.0	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.3	1.1	GO:0043375	negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.2	7.0	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.2	8.4	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.2	7.0	GO:0003094	glomerular filtration(GO:0003094)
0.2	0.7	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2	18.8	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.2	4.4	GO:0045064	T-helper 2 cell differentiation(GO:0045064)
0.2	5.0	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.2	6.1	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.2	3.7	GO:0016180	snRNA processing(GO:0016180)
0.2	1.7	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.2	1.1	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.2	2.9	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.2	1.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.1	2.5	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.1	1.0	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1	3.1	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1	3.4	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1	11.5	GO:0006611	protein export from nucleus(GO:0006611)
0.1	2.1	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	11.8	GO:0006901	vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	2.7	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	8.5	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.1	9.6	GO:0045773	positive regulation of axon extension(GO:0045773)
0.1	4.5	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	4.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	5.3	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.1	8.3	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.1	0.9	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	12.7	GO:0030038	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1	1.8	GO:0070914	UV-damage excision repair(GO:0070914)
0.1	0.8	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1	1.9	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1	8.2	GO:0070527	platelet aggregation(GO:0070527)
0.1	8.2	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.1	1.7	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	2.4	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	3.0	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	1.8	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.1	11.4	GO:0002576	platelet degranulation(GO:0002576)
0.1	0.7	GO:0048535	lymph node development(GO:0048535)
0.1	1.3	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.1	0.1	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.1	0.3	GO:2001205	TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.1	0.9	GO:0003334	keratinocyte development(GO:0003334)
0.1	1.6	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1	9.2	GO:2001020	regulation of response to DNA damage stimulus(GO:2001020)
0.1	0.7	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.9	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.0	3.5	GO:0015914	phospholipid transport(GO:0015914)
0.0	1.2	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.9	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	2.8	GO:0032418	lysosome localization(GO:0032418)
0.0	1.0	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.1	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	3.1	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	1.5	GO:0048814	regulation of dendrite morphogenesis(GO:0048814)
0.0	3.2	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	0.8	GO:0002076	osteoblast development(GO:0002076)
0.0	1.3	GO:0035065	regulation of histone acetylation(GO:0035065)
0.0	5.6	GO:0070372	regulation of ERK1 and ERK2 cascade(GO:0070372)
0.0	0.2	GO:0039530	MDA-5 signaling pathway(GO:0039530)
0.0	0.6	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	1.0	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.9	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	0.7	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	2.1	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.3	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.5	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	5.5	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.3	69.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
3.8	42.2	GO:0042612	MHC class I protein complex(GO:0042612)
3.8	18.9	GO:0042825	TAP complex(GO:0042825)
3.0	56.6	GO:0042611	MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
2.3	7.0	GO:0071753	IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
1.9	7.8	GO:0020003	symbiont-containing vacuole(GO:0020003)
1.9	9.6	GO:0043291	RAVE complex(GO:0043291)
1.6	11.5	GO:0005610	laminin-5 complex(GO:0005610)
1.1	3.4	GO:0031251	PAN complex(GO:0031251)
1.0	7.0	GO:0005683	U7 snRNP(GO:0005683)
0.8	4.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.8	19.6	GO:0005916	fascia adherens(GO:0005916)
0.7	7.8	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.7	2.7	GO:0032584	growth cone membrane(GO:0032584)
0.7	8.0	GO:0030008	TRAPP complex(GO:0030008)
0.6	3.1	GO:0019815	B cell receptor complex(GO:0019815)
0.6	2.5	GO:1990356	sumoylated E2 ligase complex(GO:1990356)
0.6	1.8	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.6	7.8	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.6	5.3	GO:0000125	PCAF complex(GO:0000125)
0.6	2.9	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.5	2.1	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.5	3.6	GO:0031415	NatA complex(GO:0031415)
0.5	9.0	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.5	8.1	GO:0000145	exocyst(GO:0000145)
0.5	5.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4	2.6	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.4	13.8	GO:0005839	proteasome core complex(GO:0005839)
0.4	20.5	GO:0097542	ciliary tip(GO:0097542)
0.4	21.6	GO:0002102	podosome(GO:0002102)
0.4	4.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.4	27.4	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.4	41.5	GO:0031594	neuromuscular junction(GO:0031594)
0.4	5.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.4	2.2	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.3	3.7	GO:0032039	integrator complex(GO:0032039)
0.3	1.5	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.3	8.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3	2.6	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.2	2.7	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2	2.5	GO:0033643	host cell part(GO:0033643)
0.2	1.3	GO:0005816	spindle pole body(GO:0005816)
0.2	0.9	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2	3.8	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	2.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.2	3.2	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2	15.1	GO:1904724	tertiary granule lumen(GO:1904724)
0.2	1.8	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2	20.3	GO:0035578	azurophil granule lumen(GO:0035578)
0.2	5.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	12.6	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	4.8	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	10.6	GO:0016328	lateral plasma membrane(GO:0016328)
0.1	2.6	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1	1.8	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	11.6	GO:0070821	tertiary granule membrane(GO:0070821)
0.1	6.2	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.1	1.1	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	10.4	GO:0016459	myosin complex(GO:0016459)
0.1	78.7	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1	3.3	GO:0032420	stereocilium(GO:0032420)
0.1	0.9	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	5.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	9.0	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1	51.1	GO:0005925	focal adhesion(GO:0005925)
0.1	28.8	GO:0010008	endosome membrane(GO:0010008)
0.1	3.0	GO:0016235	aggresome(GO:0016235)
0.1	0.8	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	24.2	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	3.4	GO:0005905	clathrin-coated pit(GO:0005905)
0.1	2.1	GO:0008180	COP9 signalosome(GO:0008180)
0.1	1.1	GO:0046930	pore complex(GO:0046930)
0.1	2.3	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.7	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	4.8	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	4.6	GO:0005769	early endosome(GO:0005769)
0.0	1.9	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	3.5	GO:0030018	Z disc(GO:0030018)
0.0	3.7	GO:0016363	nuclear matrix(GO:0016363)
0.0	6.8	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	18.2	GO:0000139	Golgi membrane(GO:0000139)
0.0	1.3	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	1.0	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	1.8	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.3	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	4.7	GO:0005759	mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.2	61.0	GO:0046979	TAP2 binding(GO:0046979)
7.2	101.1	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
4.7	18.8	GO:0004906	interferon-gamma receptor activity(GO:0004906)
3.4	17.0	GO:0042289	MHC class II protein binding(GO:0042289)
2.8	39.6	GO:0032395	MHC class II receptor activity(GO:0032395)
2.8	24.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
2.6	15.6	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
2.2	9.0	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
2.1	6.2	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
1.8	9.2	GO:0003870	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
1.8	7.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
1.7	22.0	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
1.5	8.9	GO:0035800	deubiquitinase activator activity(GO:0035800)
1.4	5.5	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
1.2	18.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
1.2	4.7	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
1.1	56.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
1.1	4.5	GO:0050659	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
1.1	3.2	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.9	6.6	GO:0001849	complement component C1q binding(GO:0001849)
0.9	2.6	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.8	6.6	GO:0019863	IgE binding(GO:0019863)
0.8	33.0	GO:0051059	NF-kappaB binding(GO:0051059)
0.8	2.3	GO:0097677	STAT family protein binding(GO:0097677)
0.7	35.0	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.7	2.9	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
0.7	33.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.7	3.5	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532) cupric ion binding(GO:1903135)
0.7	19.6	GO:0017166	vinculin binding(GO:0017166)
0.7	16.7	GO:0070628	proteasome binding(GO:0070628)
0.7	6.2	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.7	6.1	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.6	2.5	GO:0061650	ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.5	8.7	GO:0097602	cullin family protein binding(GO:0097602)
0.4	4.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.4	2.9	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3	8.5	GO:0004707	MAP kinase activity(GO:0004707)
0.3	5.5	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.3	5.4	GO:0002162	dystroglycan binding(GO:0002162)
0.3	3.7	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3	27.5	GO:0019003	GDP binding(GO:0019003)
0.3	4.7	GO:0042834	peptidoglycan binding(GO:0042834)
0.3	3.4	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.3	1.5	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3	2.7	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3	4.6	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.3	15.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3	0.9	GO:0030290	sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.3	3.4	GO:0051434	BH3 domain binding(GO:0051434)
0.3	2.0	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3	4.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.3	3.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3	13.5	GO:0008536	Ran GTPase binding(GO:0008536)
0.2	7.8	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2	3.9	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2	0.8	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.2	6.5	GO:0017025	TBP-class protein binding(GO:0017025)
0.2	3.8	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.2	3.4	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.2	1.1	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.2	1.8	GO:0008131	primary amine oxidase activity(GO:0008131)
0.2	7.8	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.2	7.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	2.5	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	1.7	GO:0008199	ferric iron binding(GO:0008199)
0.1	5.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	4.7	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	1.5	GO:0008527	taste receptor activity(GO:0008527)
0.1	34.2	GO:0003924	GTPase activity(GO:0003924)
0.1	3.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	1.7	GO:0046527	glucosyltransferase activity(GO:0046527)
0.1	9.8	GO:0008565	protein transporter activity(GO:0008565)
0.1	5.5	GO:0030331	estrogen receptor binding(GO:0030331)
0.1	1.9	GO:0031491	nucleosome binding(GO:0031491)
0.1	1.8	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	8.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	8.4	GO:0005525	GTP binding(GO:0005525)
0.1	2.6	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	1.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	8.0	GO:0008013	beta-catenin binding(GO:0008013)
0.1	0.5	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.1	1.2	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	12.0	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.1	1.3	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	10.8	GO:0001047	core promoter binding(GO:0001047)
0.0	0.3	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.9	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.8	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.6	GO:0008198	ferrous iron binding(GO:0008198)
0.0	1.7	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.9	GO:0042056	chemoattractant activity(GO:0042056)
0.0	2.3	GO:0000149	SNARE binding(GO:0000149)
0.0	0.7	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	2.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	4.7	GO:0003823	antigen binding(GO:0003823)
0.0	1.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.6	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	1.0	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	1.0	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	2.0	GO:0001618	virus receptor activity(GO:0001618)
0.0	1.7	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	4.3	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.0	0.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	1.6	GO:0017137	Rab GTPase binding(GO:0017137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	176.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
1.7	19.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
1.2	58.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.8	25.6	PID IL27 PATHWAY	IL27-mediated signaling events
0.7	34.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.7	41.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.6	11.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.5	8.9	PID IL23 PATHWAY	IL23-mediated signaling events
0.4	6.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.4	24.5	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.4	12.8	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3	24.2	PID IL12 2PATHWAY	IL12-mediated signaling events
0.3	24.1	PID IL4 2PATHWAY	IL4-mediated signaling events
0.3	3.9	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.3	9.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.3	13.4	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3	9.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.2	5.5	PID S1P S1P1 PATHWAY	S1P1 pathway
0.2	6.6	ST ADRENERGIC	Adrenergic Pathway
0.2	2.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	1.8	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	9.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	5.3	PID MYC PATHWAY	C-MYC pathway
0.1	0.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	2.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	22.1	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	4.1	PID RAS PATHWAY	Regulation of Ras family activation
0.1	3.1	PID BCR 5PATHWAY	BCR signaling pathway
0.1	2.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	2.3	PID IFNG PATHWAY	IFN-gamma pathway
0.1	5.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	8.9	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	2.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	3.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	2.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	2.0	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	1.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.8	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	42.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
3.0	33.0	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
2.8	138.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
2.3	52.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
1.5	31.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
1.2	37.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.0	17.6	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.9	18.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.8	4.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.8	37.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.7	12.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.6	19.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.5	7.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.5	4.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.5	30.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.4	22.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.4	4.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4	28.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.4	25.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.4	15.7	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.3	2.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.3	9.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	3.9	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.2	8.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	6.0	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.2	3.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.2	5.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2	3.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2	3.7	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	4.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	7.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	3.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	2.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	2.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	3.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	7.2	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.1	1.8	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.7	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1	8.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	13.6	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	4.3	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.1	1.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	5.7	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	1.7	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	2.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	6.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	1.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	2.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	2.7	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	2.2	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	1.7	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	2.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.5	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	2.6	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport