Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for RFX7_RFX4_RFX1

Z-value: 10.59

Motif logo

Transcription factors associated with RFX7_RFX4_RFX1

Gene Symbol Gene ID Gene Info
ENSG00000181827.16 RFX7
ENSG00000111783.13 RFX4
ENSG00000132005.9 RFX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX1hg38_v1_chr19_-_14006262_140063300.429.6e-11Click!
RFX7hg38_v1_chr15_-_56243829_56243891,
hg38_v1_chr15_-_56245074_56245088
0.312.2e-06Click!

Activity profile of RFX7_RFX4_RFX1 motif

Sorted Z-values of RFX7_RFX4_RFX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX7_RFX4_RFX1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr19_+_16197900 263.39 ENST00000429941.6
ENST00000291439.8
ENST00000444449.6
ENST00000589822.5
adaptor related protein complex 1 subunit mu 1
chr19_-_49813259 120.46 ENST00000313777.9
fuzzy planar cell polarity protein
chr19_-_49813223 109.93 ENST00000533418.5
fuzzy planar cell polarity protein
chr11_+_72080313 103.21 ENST00000307198.11
ENST00000538413.6
ENST00000642648.1
ENST00000289488.7
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr11_+_72080803 98.05 ENST00000423494.6
ENST00000539587.6
ENST00000536917.2
ENST00000538478.5
ENST00000324866.11
ENST00000643715.1
ENST00000439209.5
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr19_-_49813151 94.91 ENST00000528094.5
ENST00000526575.1
fuzzy planar cell polarity protein
chr11_+_72080595 93.22 ENST00000647530.1
ENST00000539271.6
ENST00000642510.1
leucine rich transmembrane and O-methyltransferase domain containing
chr3_-_128994111 81.90 ENST00000645291.2
ENST00000265068.9
cilia and flagella associated protein 92 (putative)
chr17_-_15341577 71.22 ENST00000543896.1
ENST00000395930.6
ENST00000539245.5
ENST00000539316.1
tektin 3
chr8_+_10672646 67.22 ENST00000521818.1
chromosome 8 open reading frame 74
chr8_+_93754879 63.15 ENST00000453906.6
ENST00000683362.1
ENST00000682036.1
ENST00000453321.8
ENST00000409623.8
ENST00000520680.2
ENST00000521517.6
ENST00000452276.6
transmembrane protein 67
chr19_+_2096960 63.14 ENST00000588003.5
IZUMO family member 4
chr17_+_17972813 61.07 ENST00000582416.5
ENST00000313838.12
ENST00000399187.6
ENST00000581264.5
ENST00000479684.2
ENST00000584166.5
ENST00000585108.5
ENST00000399182.5
ENST00000579977.1
dynein regulatory complex subunit 3
chr8_+_93754844 58.54 ENST00000684064.1
ENST00000498673.5
ENST00000518319.5
transmembrane protein 67
chr2_-_196068812 55.97 ENST00000410072.5
ENST00000312428.11
dynein axonemal heavy chain 7
chr19_+_2097010 55.07 ENST00000610800.1
IZUMO family member 4
chr13_-_30307539 52.67 ENST00000380615.8
katanin catalytic subunit A1 like 1
chr19_-_45792755 52.45 ENST00000377735.7
ENST00000270223.7
DM1 locus, WD repeat containing
chr8_+_143734133 49.80 ENST00000527139.7
ENST00000533004.5
IQ motif and ankyrin repeat containing 1
chr19_+_2096937 46.09 ENST00000395296.5
IZUMO family member 4
chr15_+_85380625 45.71 ENST00000560302.5
A-kinase anchoring protein 13
chr4_+_176065827 44.82 ENST00000508596.6
WD repeat domain 17
chr2_-_219245389 44.46 ENST00000428427.1
ENST00000432839.1
ENST00000295759.12
ENST00000424620.1
galactosidase beta 1 like
chr2_-_219245465 43.51 ENST00000392089.6
galactosidase beta 1 like
chr6_-_158999748 41.58 ENST00000449822.5
radial spoke head 3
chr1_+_207053229 41.36 ENST00000367080.8
ENST00000367079.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr20_+_50958805 41.17 ENST00000244051.3
molybdenum cofactor synthesis 3
chr1_-_207052980 40.40 ENST00000367084.1
YOD1 deubiquitinase
chr6_+_142147162 40.28 ENST00000452973.6
ENST00000620996.4
ENST00000367621.1
ENST00000367630.9
vesicle trafficking 1
chr19_-_46471484 39.87 ENST00000313683.15
ENST00000602246.1
PNMA family member 8A
chr7_-_130205348 39.41 ENST00000462753.5
ENST00000471077.2
ENST00000473456.5
ENST00000397622.7
transmembrane protein 209
chr17_-_7915929 39.14 ENST00000635932.1
ENST00000640240.1
ring finger protein 227
chr19_+_2096873 38.09 ENST00000395307.6
ENST00000395301.8
ENST00000620263.4
IZUMO family member 4
chr19_-_46471407 35.84 ENST00000438932.2
PNMA family member 8A
chr6_-_159000174 35.42 ENST00000367069.7
radial spoke head 3
chr2_+_61065863 34.53 ENST00000402291.6
KIAA1841
chr14_+_102777555 34.23 ENST00000539721.5
ENST00000560463.5
TNF receptor associated factor 3
chr8_-_27258414 34.17 ENST00000523048.5
stathmin 4
chr10_-_116849686 34.04 ENST00000674167.1
ENST00000674401.1
ENST00000674326.1
ENST00000674267.1
ENST00000635765.1
heat shock protein family A (Hsp70) member 12A
chr11_-_47715344 33.60 ENST00000525123.6
ENST00000528244.5
ENST00000532595.5
ENST00000529154.5
ENST00000530969.1
ATP/GTP binding protein like 2
chr6_-_162727748 33.24 ENST00000366892.5
ENST00000366898.6
ENST00000366897.5
ENST00000366896.5
ENST00000674250.1
parkin RBR E3 ubiquitin protein ligase
chr2_-_63588390 32.55 ENST00000272321.12
ENST00000409562.7
WD repeat containing planar cell polarity effector
chr6_+_162727941 32.35 ENST00000366888.6
parkin coregulated
chr2_-_61854119 32.25 ENST00000405894.3
FAM161 centrosomal protein A
chr3_+_111999326 31.79 ENST00000494932.1
transgelin 3
chr19_-_39833615 30.85 ENST00000593685.5
ENST00000600611.5
dual specificity tyrosine phosphorylation regulated kinase 1B
chr22_+_38057371 30.78 ENST00000437453.5
ENST00000356976.8
protein interacting with PRKCA 1
chr2_-_61854013 29.88 ENST00000404929.6
FAM161 centrosomal protein A
chr8_-_27258386 29.71 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
stathmin 4
chr19_+_48469354 29.70 ENST00000452733.7
ENST00000641098.1
cytohesin 2
chr1_+_206635772 29.67 ENST00000441486.5
ENST00000367106.1
dual specificity tyrosine phosphorylation regulated kinase 3
chr1_-_11805977 29.16 ENST00000376486.3
methylenetetrahydrofolate reductase
chr1_-_34859717 28.98 ENST00000423898.1
ENST00000521580.3
ENST00000456842.1
small integral membrane protein 12
chr15_-_64356047 28.83 ENST00000634654.1
casein kinase 1 gamma 1
chr14_+_70452161 28.67 ENST00000603540.2
ADAM metallopeptidase domain 21
chr1_+_206635573 28.63 ENST00000367108.7
dual specificity tyrosine phosphorylation regulated kinase 3
chr1_+_206635703 28.18 ENST00000649163.1
dual specificity tyrosine phosphorylation regulated kinase 3
chr1_+_206635521 27.71 ENST00000367109.8
dual specificity tyrosine phosphorylation regulated kinase 3
chr22_+_38057200 27.46 ENST00000404072.7
ENST00000424694.5
protein interacting with PRKCA 1
chr1_-_11805949 27.44 ENST00000376590.9
methylenetetrahydrofolate reductase
chr1_-_11805924 27.29 ENST00000418034.1
methylenetetrahydrofolate reductase
chr19_+_5681000 26.88 ENST00000581893.5
ENST00000411793.6
ENST00000301382.8
ENST00000581773.5
ENST00000339423.7
ENST00000423665.6
ENST00000583928.5
ENST00000342970.6
ENST00000422535.6
ENST00000581521.5
hydroxysteroid 11-beta dehydrogenase 1 like
chr19_+_43575801 26.83 ENST00000599207.6
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr1_-_84690255 26.56 ENST00000603677.1
SSX family member 2 interacting protein
chr9_-_87974487 25.92 ENST00000375871.8
ENST00000605159.5
ENST00000325303.9
ENST00000336654.9
cyclin dependent kinase 20
chr7_+_103075123 25.92 ENST00000323716.8
ENST00000434153.1
armadillo repeat containing 10
chr2_+_84516438 25.82 ENST00000389394.8
dynein axonemal heavy chain 6
chr15_-_64356074 25.66 ENST00000634811.1
ENST00000303052.13
ENST00000607537.6
casein kinase 1 gamma 1
chr9_-_132669969 25.50 ENST00000438527.7
DEAD-box helicase 31
chr20_+_31514410 25.43 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chr8_-_97277890 25.18 ENST00000322128.5
TSPY like 5
chr13_+_20567131 25.01 ENST00000319980.10
ENST00000351808.10
ENST00000389373.3
intraflagellar transport 88
chr1_+_11806096 24.96 ENST00000312413.10
ENST00000346436.11
chloride voltage-gated channel 6
chr20_+_833734 24.77 ENST00000304189.6
family with sequence similarity 110 member A
chr9_-_113340248 24.42 ENST00000341761.8
ENST00000374195.7
ENST00000374193.9
WD repeat domain 31
chr17_-_5500997 24.31 ENST00000568641.2
novel protein
chr5_-_138139382 23.88 ENST00000265191.4
NME/NM23 family member 5
chr14_+_104985758 23.58 ENST00000551606.5
ENST00000547315.6
clathrin binding box of aftiphilin containing 1
chr22_+_45413679 23.41 ENST00000614167.2
RIB43A domain with coiled-coils 2
chr1_+_36084079 23.23 ENST00000207457.8
tektin 2
chr1_-_235650748 22.85 ENST00000450593.5
ENST00000366598.8
G protein subunit gamma 4
chr3_-_105869035 22.78 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr19_-_3801791 22.78 ENST00000590849.1
ENST00000395045.6
megakaryocyte-associated tyrosine kinase
chr6_+_111259474 22.76 ENST00000672554.1
ENST00000673024.1
major facilitator superfamily domain containing 4B
chr16_-_72093598 22.57 ENST00000268483.8
thioredoxin like 4B
chr19_-_39834127 22.53 ENST00000601972.1
ENST00000430012.6
ENST00000323039.10
ENST00000348817.7
dual specificity tyrosine phosphorylation regulated kinase 1B
chr11_+_113314569 22.26 ENST00000429951.5
ENST00000442859.5
ENST00000531164.5
ENST00000529850.5
ENST00000529221.6
ENST00000525965.5
tetratricopeptide repeat domain 12
chr4_+_105710809 21.95 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
glutathione S-transferase C-terminal domain containing
chr19_-_38899800 21.66 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
sirtuin 2
chr9_-_135499846 21.22 ENST00000429260.7
chromosome 9 open reading frame 116
chr9_-_127715633 21.13 ENST00000335223.5
ENST00000416214.1
ENST00000543175.5
peptidyl-tRNA hydrolase 1 homolog
chr6_+_111259294 20.99 ENST00000672303.1
ENST00000671876.2
ENST00000368847.5
major facilitator superfamily domain containing 4B
chr1_-_20717996 20.95 ENST00000400463.8
ENST00000247986.2
kinesin family member 17
chr12_+_106774630 20.84 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8 guanine nucleotide exchange factor B
chr3_+_111999189 20.82 ENST00000455401.6
transgelin 3
chr17_-_17972374 20.62 ENST00000318094.14
ENST00000540946.5
ENST00000379504.8
ENST00000542206.5
ENST00000395739.8
ENST00000581396.5
ENST00000535933.5
ENST00000579586.1
target of myb1 like 2 membrane trafficking protein
chr17_+_74274229 20.44 ENST00000311014.11
dynein axonemal intermediate chain 2
chr19_+_55675191 20.40 ENST00000270460.11
ENST00000085079.11
epsin 1
chr5_-_134367144 20.40 ENST00000265334.9
cyclin dependent kinase like 3
chr17_+_74274241 20.17 ENST00000582036.5
dynein axonemal intermediate chain 2
chr17_-_66192125 19.98 ENST00000535342.7
centrosomal protein 112
chr11_-_236821 19.75 ENST00000529382.5
ENST00000528469.1
sirtuin 3
chr19_+_37469337 19.70 ENST00000330173.6
zinc finger protein 570
chr7_-_4883683 19.70 ENST00000399583.4
Rap associating with DIL domain
chr19_+_36605292 19.60 ENST00000460670.5
ENST00000292928.7
ENST00000439428.5
zinc finger protein 382
chr14_+_96392095 19.23 ENST00000267584.9
ENST00000555570.1
adenylate kinase 7
chr16_+_90022600 19.22 ENST00000620723.4
ENST00000268699.9
growth arrest specific 8
chr14_+_73644875 19.10 ENST00000554113.5
ENST00000553645.7
ENST00000555631.6
ENST00000311089.7
ENST00000555919.7
ENST00000554339.5
ENST00000554871.5
dynein axonemal light chain 1
chr12_+_100267162 19.09 ENST00000548392.5
ENST00000360820.7
SCY1 like pseudokinase 2
chr11_-_6405405 18.90 ENST00000608645.5
ENST00000618005.4
ENST00000610474.4
ENST00000608394.5
ENST00000529519.5
amyloid beta precursor protein binding family B member 1
chr4_+_127632926 18.89 ENST00000335251.11
inturned planar cell polarity protein
chr15_+_67254776 18.88 ENST00000335894.9
ENST00000512104.5
IQ motif containing H
chr2_-_27628975 18.55 ENST00000324364.4
coiled-coil domain containing 121
chr16_+_19718264 18.25 ENST00000564186.5
IQ motif containing K
chr16_+_89657855 18.25 ENST00000564238.2
spermatogenesis associated 33
chr11_+_36594369 18.18 ENST00000678060.1
ENST00000446510.6
ENST00000676979.1
ENST00000677808.1
ENST00000617650.5
ENST00000334307.10
ENST00000531554.6
ENST00000679022.1
ENST00000347206.8
ENST00000534635.5
ENST00000676921.1
ENST00000678950.1
ENST00000530697.6
ENST00000527108.6
ENST00000532470.3
intraflagellar transport associated protein
chr11_+_113314811 18.13 ENST00000393020.5
tetratricopeptide repeat domain 12
chr19_-_38899529 18.04 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr17_-_66191855 18.00 ENST00000583358.1
ENST00000392769.6
centrosomal protein 112
chr15_+_70892443 17.98 ENST00000443425.6
ENST00000560369.5
leucine rich repeat containing 49
chr12_+_100267131 17.94 ENST00000549687.5
SCY1 like pseudokinase 2
chr15_+_100602519 17.91 ENST00000332783.12
ENST00000558747.5
ENST00000343276.4
ankyrin repeat and SOCS box containing 7
chr22_-_23141980 17.35 ENST00000216036.9
radial spoke head 14 homolog
chr17_+_17476980 17.27 ENST00000580462.1
ENST00000268711.4
mediator complex subunit 9
chr14_+_75069577 17.05 ENST00000238686.8
zinc finger C2HC-type containing 1C
chr15_-_72118114 16.98 ENST00000356056.10
ENST00000569314.1
myosin IXA
chr8_+_42152946 16.40 ENST00000518421.5
ENST00000174653.3
ENST00000396926.8
ENST00000521280.5
ENST00000522288.5
adaptor related protein complex 3 subunit mu 2
chr21_-_46323806 16.21 ENST00000397680.5
ENST00000445935.5
ENST00000291691.12
ENST00000397682.7
chromosome 21 open reading frame 58
chr1_-_2391535 16.16 ENST00000378531.8
MORN repeat containing 1
chrX_-_13817346 16.08 ENST00000356942.9
glycoprotein M6B
chr14_+_75069632 15.60 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
zinc finger C2HC-type containing 1C
chr6_+_78867524 15.55 ENST00000369940.7
interleukin 1 receptor associated kinase 1 binding protein 1
chr15_+_72118392 15.48 ENST00000340912.6
SUMO peptidase family member, NEDD8 specific
chr11_+_450255 15.41 ENST00000308020.6
phosphatidylserine synthase 2
chr2_-_68157470 15.26 ENST00000406245.6
ENST00000409164.1
ENST00000295121.11
WD repeat domain 92
chr9_+_132670458 15.15 ENST00000372146.5
general transcription factor IIIC subunit 4
chr10_-_51699559 15.12 ENST00000331173.6
cleavage stimulation factor subunit 2 tau variant
chr15_-_55498317 15.05 ENST00000568310.1
ENST00000565113.5
ENST00000448430.6
ENST00000457155.6
DNAAF4-CCPG1 readthrough (NMD candidate)
dynein axonemal assembly factor 4
chr1_-_169427408 15.00 ENST00000367806.7
coiled-coil domain containing 181
chr9_+_77177511 14.99 ENST00000360280.8
ENST00000645632.1
ENST00000643348.1
vacuolar protein sorting 13 homolog A
chr18_+_35041387 14.98 ENST00000538170.6
ENST00000300249.10
ENST00000588910.5
microtubule associated protein RP/EB family member 2
chr20_-_3173516 14.89 ENST00000360342.7
ENST00000645462.1
ENST00000337576.7
leucine zipper tumor suppressor family member 3
chr19_-_45815228 14.69 ENST00000597055.1
radial spoke head 6 homolog A
chr1_+_117606040 14.61 ENST00000369448.4
terminal nucleotidyltransferase 5C
chr19_-_4723749 14.58 ENST00000597849.5
ENST00000598800.5
ENST00000602161.5
ENST00000262960.14
ENST00000597726.5
ENST00000601130.5
dipeptidyl peptidase 9
chr11_-_62754141 14.52 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
zinc finger and BTB domain containing 3
chr3_-_45842066 14.50 ENST00000445698.1
ENST00000296135.11
leucine zipper transcription factor like 1
chr12_+_110614027 14.40 ENST00000550703.6
ENST00000551590.5
tectonic family member 1
chr7_+_156640879 14.31 ENST00000311822.12
ring finger protein 32
chr14_-_21536928 14.06 ENST00000613414.4
spalt like transcription factor 2
chrX_+_136169891 14.00 ENST00000449474.5
four and a half LIM domains 1
chr1_+_27726005 13.97 ENST00000530324.5
ENST00000234549.11
ENST00000373949.5
ENST00000010299.10
family with sequence similarity 76 member A
chr1_+_27725945 13.91 ENST00000373954.11
ENST00000419687.6
family with sequence similarity 76 member A
chr7_+_2559101 13.79 ENST00000404984.5
ENST00000611775.4
IQ motif containing E
chr19_+_49818271 13.77 ENST00000312865.10
ENST00000593767.3
ENST00000538643.5
ENST00000595185.5
mediator complex subunit 25
chr19_+_58451607 13.73 ENST00000545523.5
ENST00000599194.5
ENST00000336614.9
ENST00000598244.5
ENST00000599193.5
ENST00000594214.1
zinc finger protein 324B
chr9_-_87974667 13.63 ENST00000375883.7
cyclin dependent kinase 20
chr6_+_146598961 13.63 ENST00000522242.5
ENST00000397944.8
androglobin
chr19_-_10569022 13.62 ENST00000335766.2
cyclin dependent kinase inhibitor 2D
chr2_-_175005357 13.61 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr6_-_142147122 13.60 ENST00000258042.2
neuromedin B receptor
chr19_+_2328663 13.58 ENST00000614794.4
ENST00000613503.5
ENST00000610743.4
ENST00000618220.4
signal peptide peptidase like 2B
chr13_+_42272134 13.56 ENST00000025301.4
A-kinase anchoring protein 11
chr11_-_72080389 13.54 ENST00000351960.10
ENST00000541719.5
ENST00000535111.5
nuclear mitotic apparatus protein 1
chr1_-_39691450 13.50 ENST00000612703.3
ENST00000617690.2
hippocalcin like 4
chr19_-_10568968 13.47 ENST00000393599.3
cyclin dependent kinase inhibitor 2D
chrX_-_132489954 13.45 ENST00000370844.5
muscleblind like splicing regulator 3
chr1_-_39691393 13.45 ENST00000372844.8
hippocalcin like 4
chr3_+_111998739 13.26 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr7_+_158856551 13.16 ENST00000407559.8
dynein 2 intermediate chain 1
chr15_+_70892809 13.07 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr1_-_169427428 13.06 ENST00000456107.1
ENST00000367805.7
ENST00000491570.2
coiled-coil domain containing 181
chr19_+_58476156 13.01 ENST00000600013.5
ENST00000594369.6
zinc finger protein 446
chr10_-_122954184 12.98 ENST00000481909.2
chromosome 10 open reading frame 88
chr1_-_84690406 12.98 ENST00000605755.5
ENST00000342203.8
ENST00000437941.6
SSX family member 2 interacting protein
chr7_+_149838365 12.94 ENST00000460379.1
ENST00000223210.5
zinc finger protein 862
chr10_-_97401277 12.90 ENST00000315563.10
ENST00000370992.9
ENST00000414986.5
ribosomal RNA processing 12 homolog
chr19_+_52274443 12.80 ENST00000600821.5
ENST00000595149.5
ENST00000595000.5
ENST00000593612.1
zinc finger protein 766
chr18_-_35377296 12.80 ENST00000587422.1
ENST00000589332.7
ENST00000306346.5
ENST00000586687.5
ENST00000585522.1
zinc finger protein 396
chr20_-_49915509 12.70 ENST00000289431.10
spermatogenesis associated 2
chr1_-_86396253 12.67 ENST00000394733.2
ENST00000359242.7
ENST00000294678.6
ENST00000479890.5
ENST00000478286.2
ENST00000370566.7
ENST00000317336.11
outer dense fiber of sperm tails 2 like
chr2_-_218671975 12.61 ENST00000295704.7
ring finger protein 25
chr14_-_87993143 12.58 ENST00000622264.4
galactosylceramidase
chr19_+_10106688 12.45 ENST00000430370.1
peter pan homolog
chr6_-_119149124 12.33 ENST00000368475.8
family with sequence similarity 184 member A
chr17_-_7204502 12.19 ENST00000486626.8
ENST00000648263.1
discs large MAGUK scaffold protein 4
chr3_-_28348805 12.14 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr14_-_87992838 12.13 ENST00000544807.6
galactosylceramidase
chr11_-_6419051 12.10 ENST00000299402.10
ENST00000532020.2
ENST00000609360.6
ENST00000389906.6
amyloid beta precursor protein binding family B member 1
chr2_+_218710821 12.07 ENST00000392102.6
ENST00000457313.5
ENST00000415717.5
tubulin tyrosine ligase like 4
chr15_-_55408245 12.06 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
cell cycle progression 1
chr22_+_23145366 12.03 ENST00000341989.9
ENST00000263116.8
RAB36, member RAS oncogene family
chr19_+_48469202 12.02 ENST00000427476.4
cytohesin 2
chr3_+_111998915 12.00 ENST00000478951.6
transgelin 3
chr7_+_156640702 11.96 ENST00000432459.6
ring finger protein 32
chr16_+_57372465 11.87 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr17_-_7205116 11.84 ENST00000649520.1
ENST00000649186.1
discs large MAGUK scaffold protein 4
chr4_-_145180496 11.82 ENST00000447906.8
OTU deubiquitinase 4
chr11_-_72080472 11.76 ENST00000537217.5
ENST00000366394.7
ENST00000358965.10
ENST00000546131.1
ENST00000393695.8
ENST00000543937.5
ENST00000368959.9
ENST00000541641.5
nuclear mitotic apparatus protein 1
chrX_+_136169833 11.59 ENST00000628032.2
four and a half LIM domains 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
81.3 325.3 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
19.0 114.2 GO:0035617 stress granule disassembly(GO:0035617)
17.8 71.2 GO:0080154 regulation of fertilization(GO:0080154)
15.5 294.5 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
14.0 83.9 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
13.7 41.2 GO:0018307 tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
13.5 40.4 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
13.2 39.7 GO:2000777 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
13.2 263.4 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
11.4 45.7 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
11.2 33.5 GO:0055048 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
11.1 33.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
10.9 32.6 GO:0016476 regulation of embryonic cell shape(GO:0016476) glomerular visceral epithelial cell migration(GO:0090521)
10.5 31.4 GO:0006683 galactosylceramide catabolic process(GO:0006683)
10.3 31.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
9.6 48.0 GO:0008063 Toll signaling pathway(GO:0008063)
8.4 33.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
7.9 165.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
7.5 52.7 GO:0051013 microtubule severing(GO:0051013)
7.2 21.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
7.0 20.9 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
6.9 41.4 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
6.8 121.7 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
6.4 19.1 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
5.9 71.0 GO:0003351 epithelial cilium movement(GO:0003351)
5.8 58.2 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
5.1 46.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
4.8 14.5 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
4.8 19.3 GO:0018095 protein polyglutamylation(GO:0018095)
4.6 18.4 GO:0061511 centriole elongation(GO:0061511)
4.0 12.1 GO:0044565 dendritic cell proliferation(GO:0044565)
3.9 35.5 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
3.8 3.8 GO:0061551 trigeminal ganglion development(GO:0061551)
3.6 14.3 GO:1905224 clathrin-coated pit assembly(GO:1905224)
3.6 10.7 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
3.3 9.9 GO:1905154 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154)
3.3 9.8 GO:1903538 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
3.1 9.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
2.8 8.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
2.7 27.1 GO:0048102 autophagic cell death(GO:0048102)
2.7 37.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
2.6 15.3 GO:0016926 protein desumoylation(GO:0016926)
2.5 39.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
2.4 7.3 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
2.4 7.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
2.3 27.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.2 11.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
2.2 6.7 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
2.2 6.6 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
2.1 6.4 GO:0039023 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
2.1 8.4 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
2.0 14.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
2.0 24.0 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
2.0 7.9 GO:0071918 urea transmembrane transport(GO:0071918)
1.9 13.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.9 15.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
1.9 28.4 GO:0035082 axoneme assembly(GO:0035082)
1.8 5.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
1.8 14.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.8 19.8 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
1.8 22.8 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
1.7 15.6 GO:0098535 de novo centriole assembly(GO:0098535)
1.7 6.9 GO:0098904 regulation of AV node cell action potential(GO:0098904)
1.7 39.0 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
1.7 16.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.6 4.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.6 14.5 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) fat pad development(GO:0060613) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
1.6 71.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
1.6 9.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.6 43.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.6 63.9 GO:0007019 microtubule depolymerization(GO:0007019)
1.5 6.1 GO:0072092 ureteric bud invasion(GO:0072092)
1.5 43.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
1.5 4.5 GO:0061074 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
1.5 4.5 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
1.4 15.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
1.4 4.1 GO:0030573 bile acid catabolic process(GO:0030573)
1.4 1.4 GO:0003341 cilium movement(GO:0003341)
1.4 4.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.4 9.5 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
1.3 24.9 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.3 10.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.3 3.9 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
1.3 3.8 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.2 48.0 GO:0060612 adipose tissue development(GO:0060612)
1.2 8.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
1.2 18.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
1.2 4.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
1.1 14.0 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
1.0 11.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
1.0 11.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
1.0 11.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.0 38.0 GO:0097120 receptor localization to synapse(GO:0097120)
1.0 16.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.0 8.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
1.0 8.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
1.0 4.0 GO:0050893 sensory processing(GO:0050893)
1.0 16.7 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.9 3.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.9 2.7 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.9 5.4 GO:0007341 penetration of zona pellucida(GO:0007341) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.9 24.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.9 4.4 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.9 3.5 GO:0006288 base-excision repair, DNA ligation(GO:0006288) negative regulation of protein ADP-ribosylation(GO:0010836)
0.9 30.6 GO:0030517 negative regulation of axon extension(GO:0030517)
0.9 13.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.9 2.6 GO:0044805 late nucleophagy(GO:0044805)
0.9 3.4 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.8 10.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.8 8.3 GO:0015871 choline transport(GO:0015871)
0.8 21.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.8 3.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.8 7.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.8 2.4 GO:0051026 chiasma assembly(GO:0051026)
0.8 2.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.8 6.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.7 0.7 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.7 10.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 4.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.6 6.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.6 6.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.6 10.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.6 38.8 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.6 21.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.6 8.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.6 3.5 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.6 1.7 GO:0099404 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.6 17.9 GO:0015695 organic cation transport(GO:0015695)
0.6 6.3 GO:0007099 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.6 4.0 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.6 2.8 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.5 3.2 GO:0006548 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.5 2.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.5 3.2 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.5 2.1 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.5 1.6 GO:0043605 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.5 9.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.5 3.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.5 1.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.5 13.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.5 20.8 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.5 20.6 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.5 1.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.5 18.5 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.5 6.8 GO:0045475 locomotor rhythm(GO:0045475)
0.5 8.1 GO:0097264 self proteolysis(GO:0097264)
0.4 26.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.4 7.4 GO:0006004 fucose metabolic process(GO:0006004)
0.4 7.4 GO:0090344 negative regulation of cell aging(GO:0090344)
0.4 3.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.4 22.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.4 4.5 GO:0030916 otic vesicle formation(GO:0030916)
0.4 7.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.4 45.6 GO:0007286 spermatid development(GO:0007286)
0.4 5.1 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.4 5.8 GO:0002021 response to dietary excess(GO:0002021)
0.4 2.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.4 8.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.4 2.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.4 1.4 GO:0044240 activation of phospholipase A2 activity(GO:0032431) multicellular organism lipid catabolic process(GO:0044240)
0.3 6.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.3 52.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.3 4.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.3 8.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.3 17.1 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.3 8.2 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.3 10.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.3 5.6 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.3 3.1 GO:0015074 DNA integration(GO:0015074)
0.3 1.9 GO:0002638 negative regulation of immunoglobulin production(GO:0002638)
0.3 11.6 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.3 1.6 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.3 1.6 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.3 24.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3 10.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 7.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.2 4.2 GO:0035411 catenin import into nucleus(GO:0035411)
0.2 2.4 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111) negative regulation of microtubule polymerization(GO:0031115)
0.2 25.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.2 12.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.2 11.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.2 4.6 GO:0051412 response to corticosterone(GO:0051412)
0.2 3.8 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889)
0.2 2.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 3.2 GO:0001759 organ induction(GO:0001759)
0.2 0.6 GO:0035811 negative regulation of urine volume(GO:0035811)
0.2 13.1 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2 7.4 GO:0018149 peptide cross-linking(GO:0018149)
0.2 9.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.2 2.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2 1.3 GO:0023021 termination of signal transduction(GO:0023021)
0.2 2.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 5.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 4.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 7.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 8.5 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 6.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 3.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 3.7 GO:0030317 sperm motility(GO:0030317)
0.1 2.4 GO:0097503 sialylation(GO:0097503)
0.1 2.1 GO:0003094 glomerular filtration(GO:0003094)
0.1 6.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 3.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 13.6 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1 12.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 2.9 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.1 7.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 2.5 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 8.1 GO:0030282 bone mineralization(GO:0030282)
0.1 4.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 3.0 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 1.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 5.3 GO:0016486 peptide hormone processing(GO:0016486)
0.1 2.5 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 4.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 3.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.2 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) positive regulation of cardiac muscle cell differentiation(GO:2000727)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 3.0 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 3.0 GO:0032418 lysosome localization(GO:0032418)
0.1 8.6 GO:0007219 Notch signaling pathway(GO:0007219)
0.1 4.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 5.0 GO:0060996 dendritic spine development(GO:0060996)
0.1 3.4 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 4.0 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 1.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 2.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.7 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 1.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 4.9 GO:0019827 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.0 2.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.7 GO:0032620 interleukin-17 production(GO:0032620)
0.0 3.1 GO:0070268 cornification(GO:0070268)
0.0 1.7 GO:0070830 epithelial cell morphogenesis(GO:0003382) bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 1.5 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 5.7 GO:0007601 visual perception(GO:0007601)
0.0 1.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 1.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 2.0 GO:0044243 multicellular organism catabolic process(GO:0044243)
0.0 19.9 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 2.7 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.2 GO:0009060 aerobic respiration(GO:0009060)
0.0 1.4 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.2 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
12.5 150.0 GO:0005858 axonemal dynein complex(GO:0005858)
11.2 33.5 GO:0061673 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
8.7 164.4 GO:0036038 MKS complex(GO:0036038)
7.8 39.0 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
5.9 41.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
5.5 279.8 GO:0030131 clathrin adaptor complex(GO:0030131)
5.5 32.8 GO:0002177 manchette(GO:0002177)
5.2 15.6 GO:0098536 deuterosome(GO:0098536)
4.7 14.0 GO:0044609 DBIRD complex(GO:0044609)
4.5 27.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
4.5 13.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
4.4 39.7 GO:0072687 meiotic spindle(GO:0072687)
3.7 47.9 GO:0060077 inhibitory synapse(GO:0060077)
3.5 31.3 GO:0044447 axoneme part(GO:0044447)
3.4 31.0 GO:1990761 growth cone lamellipodium(GO:1990761)
3.4 78.8 GO:0030992 intraciliary transport particle B(GO:0030992)
3.3 10.0 GO:0016939 kinesin II complex(GO:0016939)
2.9 214.7 GO:0036126 sperm flagellum(GO:0036126)
2.7 48.0 GO:0035631 CD40 receptor complex(GO:0035631)
2.3 11.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
2.1 52.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
2.1 6.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
2.1 14.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
2.0 14.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
2.0 79.0 GO:0034451 centriolar satellite(GO:0034451)
1.9 95.0 GO:0016235 aggresome(GO:0016235)
1.8 10.7 GO:1990769 proximal neuron projection(GO:1990769)
1.8 8.9 GO:0070847 core mediator complex(GO:0070847)
1.7 24.0 GO:0098839 postsynaptic density membrane(GO:0098839)
1.5 21.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
1.4 110.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
1.4 11.2 GO:0045179 apical cortex(GO:0045179)
1.3 3.8 GO:0034464 BBSome(GO:0034464)
1.3 18.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.1 10.1 GO:0097427 microtubule bundle(GO:0097427)
1.1 29.2 GO:0005682 U5 snRNP(GO:0005682)
1.0 17.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.9 5.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.9 44.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.9 13.9 GO:0031045 dense core granule(GO:0031045)
0.8 11.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.8 10.4 GO:0031209 SCAR complex(GO:0031209)
0.7 8.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.7 36.6 GO:0036064 ciliary basal body(GO:0036064)
0.7 2.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.6 1.7 GO:0031933 telomeric heterochromatin(GO:0031933)
0.6 7.3 GO:0016600 flotillin complex(GO:0016600)
0.5 17.3 GO:0016592 mediator complex(GO:0016592)
0.5 2.5 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.5 4.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 32.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 10.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.4 5.3 GO:0000242 pericentriolar material(GO:0000242)
0.4 3.5 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.4 77.2 GO:0030426 growth cone(GO:0030426)
0.4 56.0 GO:0005884 actin filament(GO:0005884)
0.4 3.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 5.0 GO:0033010 paranodal junction(GO:0033010)
0.3 13.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 22.9 GO:0008021 synaptic vesicle(GO:0008021)
0.3 71.9 GO:0005929 cilium(GO:0005929)
0.3 18.3 GO:0005902 microvillus(GO:0005902)
0.3 87.6 GO:0045202 synapse(GO:0045202)
0.3 3.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 20.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 6.8 GO:0034707 chloride channel complex(GO:0034707)
0.3 7.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 26.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 6.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 58.2 GO:0016324 apical plasma membrane(GO:0016324)
0.2 0.7 GO:0042611 MHC protein complex(GO:0042611)
0.2 119.3 GO:0010008 endosome membrane(GO:0010008)
0.2 35.3 GO:0043202 lysosomal lumen(GO:0043202)
0.2 7.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 4.6 GO:0035371 microtubule plus-end(GO:0035371)
0.2 1.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 8.7 GO:0001533 cornified envelope(GO:0001533)
0.2 2.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 302.1 GO:0042995 cell projection(GO:0042995)
0.2 12.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 2.4 GO:0032300 mismatch repair complex(GO:0032300)
0.1 5.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 7.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 4.2 GO:0045095 keratin filament(GO:0045095)
0.1 4.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 6.1 GO:0009986 cell surface(GO:0009986)
0.1 6.8 GO:0036477 somatodendritic compartment(GO:0036477)
0.1 1.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 9.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 100.3 GO:0005615 extracellular space(GO:0005615)
0.1 7.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 1.4 GO:0031672 A band(GO:0031672)
0.0 0.6 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 81.0 GO:0005886 plasma membrane(GO:0005886)
0.0 3.5 GO:0001650 fibrillar center(GO:0001650)
0.0 2.3 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
32.7 294.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
14.0 83.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
13.5 40.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
13.2 39.7 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
10.5 31.4 GO:0004336 galactosylceramidase activity(GO:0004336)
9.8 88.0 GO:0004565 beta-galactosidase activity(GO:0004565)
8.2 41.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
7.9 39.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
7.5 52.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
7.1 21.2 GO:0045322 unmethylated CpG binding(GO:0045322)
6.9 41.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
6.6 132.3 GO:0045503 dynein light chain binding(GO:0045503)
5.8 29.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
5.6 39.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
5.4 43.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
5.3 121.7 GO:0031005 filamin binding(GO:0031005)
4.2 21.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
3.8 11.5 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
3.8 38.1 GO:0051011 microtubule minus-end binding(GO:0051011)
3.6 10.7 GO:0005137 interleukin-5 receptor binding(GO:0005137)
3.5 10.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
3.3 10.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
3.3 45.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
3.1 40.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
3.0 24.0 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
2.9 17.3 GO:0045504 dynein heavy chain binding(GO:0045504)
2.7 13.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
2.6 7.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
2.6 15.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
2.4 7.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938) alpha-2C adrenergic receptor binding(GO:0031696)
2.4 9.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.4 7.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
2.2 2.2 GO:0097108 hedgehog family protein binding(GO:0097108)
2.1 35.8 GO:0031996 thioesterase binding(GO:0031996)
2.1 178.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
2.0 10.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
2.0 35.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
2.0 7.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
1.9 27.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.8 5.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
1.7 15.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
1.7 5.0 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.6 6.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.5 30.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.5 43.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
1.4 5.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.4 8.3 GO:0039552 RIG-I binding(GO:0039552)
1.4 4.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
1.3 15.8 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
1.2 7.4 GO:0070568 guanylyltransferase activity(GO:0070568)
1.2 20.8 GO:0048156 tau protein binding(GO:0048156)
1.2 8.5 GO:0000182 rDNA binding(GO:0000182)
1.2 19.8 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
1.1 47.6 GO:0048487 beta-tubulin binding(GO:0048487)
1.1 33.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.1 4.5 GO:0035939 microsatellite binding(GO:0035939)
1.1 3.2 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
1.1 10.5 GO:0005549 odorant binding(GO:0005549)
1.0 9.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.0 26.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
1.0 20.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
1.0 20.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.9 8.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.9 5.6 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.9 19.2 GO:0019206 nucleoside kinase activity(GO:0019206)
0.9 3.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.9 6.9 GO:0071253 connexin binding(GO:0071253)
0.8 5.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.8 6.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.7 11.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.7 13.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.7 7.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.7 17.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 2.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.6 11.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.6 2.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.6 30.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.6 8.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 21.2 GO:0030332 cyclin binding(GO:0030332)
0.6 3.5 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.6 14.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.6 1.7 GO:0015616 DNA translocase activity(GO:0015616)
0.6 3.4 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.6 17.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.6 34.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.5 15.4 GO:0071949 FAD binding(GO:0071949)
0.5 6.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.5 10.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.5 8.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.5 26.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.5 19.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.5 7.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.5 15.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.5 5.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.4 3.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 29.5 GO:0030276 clathrin binding(GO:0030276)
0.4 3.5 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.4 5.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 13.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.4 128.9 GO:0015631 tubulin binding(GO:0015631)
0.4 13.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 9.8 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.4 3.2 GO:0016015 morphogen activity(GO:0016015)
0.4 6.8 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.3 4.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 38.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 8.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 8.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.3 4.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 3.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 4.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 5.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 6.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 10.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 2.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 15.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 7.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 6.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.2 8.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 8.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 2.9 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 2.3 GO:0051434 BH3 domain binding(GO:0051434)
0.2 1.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 3.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 27.4 GO:0044325 ion channel binding(GO:0044325)
0.2 3.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 2.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 1.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 2.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 1.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 6.2 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 4.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 13.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 1.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 2.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 9.1 GO:0001618 virus receptor activity(GO:0001618)
0.1 2.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 3.4 GO:0030507 spectrin binding(GO:0030507)
0.1 8.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 13.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 19.9 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 2.3 GO:0050681 androgen receptor binding(GO:0050681)
0.1 3.7 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 3.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 18.9 GO:0005096 GTPase activator activity(GO:0005096)
0.1 4.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 3.6 GO:0030165 PDZ domain binding(GO:0030165)
0.1 8.3 GO:0003823 antigen binding(GO:0003823)
0.0 1.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 3.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 9.6 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 2.6 GO:0004497 monooxygenase activity(GO:0004497)
0.0 3.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 10.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 4.6 GO:0051015 actin filament binding(GO:0051015)
0.0 1.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 5.3 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.1 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 244.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
1.7 54.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
1.4 36.6 PID ARF 3PATHWAY Arf1 pathway
1.4 90.6 PID CD40 PATHWAY CD40/CD40L signaling
1.2 18.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
1.1 42.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
1.1 5.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.9 10.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.7 48.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.6 10.9 PID IL5 PATHWAY IL5-mediated signaling events
0.6 24.0 ST GA12 PATHWAY G alpha 12 Pathway
0.6 17.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.6 7.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.5 11.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.5 32.7 PID PLK1 PATHWAY PLK1 signaling events
0.5 23.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.5 20.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.4 26.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.4 13.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.4 33.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 16.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.3 9.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 8.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 4.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 6.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 13.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 12.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 8.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 1.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 7.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 4.0 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 7.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 0.8 ST GAQ PATHWAY G alpha q Pathway
0.1 4.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 4.0 PID BMP PATHWAY BMP receptor signaling
0.1 1.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 3.8 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 18.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 14.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.4 ST ADRENERGIC Adrenergic Pathway
0.0 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 5.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
18.8 263.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
2.6 33.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
2.2 58.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
2.2 48.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
1.9 40.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.6 125.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
1.5 4.6 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
1.2 27.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
1.0 22.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.9 51.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.8 15.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.8 10.7 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.8 31.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.6 11.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 28.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.5 10.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5 14.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 8.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.4 10.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 7.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 3.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 4.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 6.7 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3 51.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.3 7.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 4.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.3 6.9 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.3 10.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 12.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.3 7.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 17.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3 8.9 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.3 6.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 7.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 16.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 6.8 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.2 6.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 13.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 3.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 1.4 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.2 6.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 10.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 4.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 58.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.2 10.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 3.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 12.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 6.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 14.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.4 REACTOME MEIOSIS Genes involved in Meiosis
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 3.8 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 2.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 5.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 6.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 8.4 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.1 1.4 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.1 1.7 REACTOME KINESINS Genes involved in Kinesins
0.1 3.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 5.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 2.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 3.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives