avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
SHOX
|
ENSG00000185960.14 | SHOX |
SHOX
|
ENSG00000185960.14 | SHOX |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 25.2 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
3.2 | 32.5 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
1.9 | 5.7 | GO:0034769 | basement membrane disassembly(GO:0034769) |
1.7 | 6.7 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
1.7 | 5.0 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
1.5 | 4.4 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
1.1 | 3.4 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
1.0 | 2.9 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.9 | 10.8 | GO:0051612 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.8 | 2.5 | GO:1904397 | retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397) |
0.8 | 13.0 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.7 | 8.2 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
0.7 | 64.4 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
0.7 | 2.1 | GO:0098582 | innate vocalization behavior(GO:0098582) |
0.7 | 15.3 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.7 | 2.0 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
0.7 | 2.6 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
0.6 | 4.7 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
0.6 | 2.3 | GO:0010645 | regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) |
0.5 | 4.2 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
0.5 | 1.5 | GO:0046878 | positive regulation of saliva secretion(GO:0046878) |
0.5 | 3.4 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
0.4 | 10.3 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
0.4 | 4.4 | GO:0009449 | glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449) |
0.4 | 2.4 | GO:0072502 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.4 | 5.3 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.3 | 2.7 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.3 | 4.5 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
0.3 | 1.0 | GO:1904383 | response to sodium phosphate(GO:1904383) |
0.3 | 1.3 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
0.3 | 3.7 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.3 | 0.9 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) |
0.3 | 1.2 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
0.3 | 12.3 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.3 | 1.3 | GO:0048023 | positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378) |
0.3 | 5.1 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
0.3 | 1.5 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
0.2 | 2.1 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.2 | 2.5 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
0.2 | 2.4 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.2 | 1.1 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) |
0.2 | 1.3 | GO:0018343 | protein farnesylation(GO:0018343) |
0.2 | 2.3 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.2 | 1.4 | GO:1902231 | positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.2 | 0.8 | GO:0015722 | canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823) |
0.2 | 1.0 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
0.2 | 0.6 | GO:0002665 | negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017) |
0.2 | 0.6 | GO:1905072 | apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
0.2 | 4.7 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
0.2 | 0.2 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
0.2 | 0.6 | GO:0010159 | specification of organ position(GO:0010159) |
0.2 | 0.5 | GO:0061011 | hepatic duct development(GO:0061011) hepatoblast differentiation(GO:0061017) |
0.2 | 2.8 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.2 | 0.8 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
0.1 | 0.4 | GO:0021530 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.1 | 0.6 | GO:0021759 | globus pallidus development(GO:0021759) |
0.1 | 1.1 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
0.1 | 0.5 | GO:0021764 | amygdala development(GO:0021764) |
0.1 | 3.9 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
0.1 | 0.4 | GO:0045715 | negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
0.1 | 1.2 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.1 | 1.0 | GO:1903961 | positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961) |
0.1 | 0.6 | GO:0089712 | L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712) |
0.1 | 0.8 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.1 | 1.1 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
0.1 | 4.0 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
0.1 | 0.7 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731) |
0.1 | 2.1 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
0.1 | 0.3 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
0.1 | 0.6 | GO:0050955 | thermoception(GO:0050955) |
0.1 | 0.3 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
0.1 | 2.1 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.1 | 1.1 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.1 | 2.1 | GO:0034776 | response to histamine(GO:0034776) cellular response to histamine(GO:0071420) |
0.1 | 2.6 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
0.1 | 0.7 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.1 | 3.2 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
0.1 | 0.8 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.1 | 1.1 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.1 | 0.5 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.1 | 0.2 | GO:0070662 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662) |
0.1 | 0.6 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
0.1 | 0.2 | GO:0042427 | serotonin biosynthetic process(GO:0042427) |
0.1 | 0.3 | GO:0002384 | hepatic immune response(GO:0002384) |
0.1 | 1.0 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
0.1 | 1.6 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
0.1 | 0.7 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.1 | 0.3 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.1 | 9.5 | GO:0002377 | immunoglobulin production(GO:0002377) |
0.1 | 2.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 0.6 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
0.1 | 0.4 | GO:0042713 | sperm ejaculation(GO:0042713) Sertoli cell proliferation(GO:0060011) |
0.1 | 0.3 | GO:0060748 | tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) |
0.0 | 1.3 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
0.0 | 0.1 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
0.0 | 0.3 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.0 | 2.5 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
0.0 | 3.1 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 3.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.0 | 1.0 | GO:0007530 | sex determination(GO:0007530) |
0.0 | 0.9 | GO:0098856 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
0.0 | 6.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.3 | GO:0051573 | negative regulation of histone H3-K9 methylation(GO:0051573) |
0.0 | 1.5 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
0.0 | 0.3 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
0.0 | 0.1 | GO:0033306 | phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173) |
0.0 | 0.6 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
0.0 | 0.6 | GO:0042135 | neurotransmitter catabolic process(GO:0042135) |
0.0 | 0.5 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
0.0 | 0.5 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
0.0 | 0.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.7 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
0.0 | 1.2 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
0.0 | 0.3 | GO:0032196 | transposition(GO:0032196) |
0.0 | 1.1 | GO:0018149 | peptide cross-linking(GO:0018149) |
0.0 | 0.1 | GO:0015692 | lead ion transport(GO:0015692) |
0.0 | 0.4 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
0.0 | 0.8 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
0.0 | 0.5 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 0.2 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
0.0 | 0.6 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
0.0 | 1.3 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.6 | GO:0033081 | regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398) |
0.0 | 0.8 | GO:0039694 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
0.0 | 0.3 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
0.0 | 0.6 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.0 | 2.7 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
0.0 | 0.7 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
0.0 | 1.7 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 8.3 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
0.0 | 0.7 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.9 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
0.0 | 0.3 | GO:0060122 | inner ear receptor stereocilium organization(GO:0060122) |
0.0 | 0.5 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.0 | 0.2 | GO:1901018 | positive regulation of potassium ion transmembrane transporter activity(GO:1901018) |
0.0 | 0.1 | GO:0036269 | swimming behavior(GO:0036269) |
0.0 | 0.9 | GO:0043631 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
0.0 | 0.3 | GO:0007625 | grooming behavior(GO:0007625) |
0.0 | 0.2 | GO:0051382 | kinetochore assembly(GO:0051382) |
0.0 | 0.0 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
0.0 | 0.9 | GO:0006953 | acute-phase response(GO:0006953) |
0.0 | 0.1 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.0 | 0.4 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
0.0 | 1.2 | GO:1901379 | regulation of potassium ion transmembrane transport(GO:1901379) |
0.0 | 0.6 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
0.0 | 0.2 | GO:0040032 | parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
0.0 | 1.6 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
0.0 | 0.0 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.0 | 1.2 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
0.0 | 2.3 | GO:0009408 | response to heat(GO:0009408) |
0.0 | 0.5 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.4 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.0 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
0.0 | 1.2 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 5.3 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.8 | 5.7 | GO:0036021 | endolysosome lumen(GO:0036021) |
0.8 | 13.0 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.8 | 5.3 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
0.7 | 2.6 | GO:0002945 | cyclin K-CDK13 complex(GO:0002945) |
0.6 | 30.6 | GO:0031430 | M band(GO:0031430) |
0.4 | 2.7 | GO:0032584 | growth cone membrane(GO:0032584) |
0.3 | 4.7 | GO:0005869 | dynactin complex(GO:0005869) |
0.3 | 1.3 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.3 | 0.8 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.3 | 4.1 | GO:0043073 | germ cell nucleus(GO:0043073) |
0.2 | 2.7 | GO:0005955 | calcineurin complex(GO:0005955) |
0.2 | 3.5 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.2 | 4.5 | GO:0031045 | dense core granule(GO:0031045) |
0.2 | 2.0 | GO:0005614 | interstitial matrix(GO:0005614) |
0.2 | 0.8 | GO:0071546 | pi-body(GO:0071546) |
0.2 | 1.0 | GO:0014802 | terminal cisterna(GO:0014802) |
0.2 | 1.5 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
0.2 | 3.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.2 | 2.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.2 | 3.4 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.2 | 1.4 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.2 | 2.6 | GO:0030914 | STAGA complex(GO:0030914) |
0.2 | 0.5 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
0.1 | 3.4 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.1 | 1.1 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
0.1 | 5.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.1 | 0.7 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
0.1 | 0.4 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
0.1 | 5.1 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
0.1 | 15.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.1 | 5.0 | GO:0032590 | dendrite membrane(GO:0032590) |
0.1 | 0.8 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
0.1 | 3.1 | GO:1990752 | microtubule end(GO:1990752) |
0.1 | 1.2 | GO:0008091 | spectrin(GO:0008091) |
0.1 | 22.4 | GO:0043209 | myelin sheath(GO:0043209) |
0.1 | 23.8 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.1 | 2.1 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.1 | 0.4 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.1 | 0.7 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.1 | 0.3 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
0.1 | 0.2 | GO:0044307 | dendritic branch(GO:0044307) |
0.1 | 0.6 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.3 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
0.0 | 0.7 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
0.0 | 4.9 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.9 | GO:0031672 | A band(GO:0031672) |
0.0 | 2.0 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 2.3 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 3.6 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.0 | 1.3 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
0.0 | 73.5 | GO:0031226 | intrinsic component of plasma membrane(GO:0031226) |
0.0 | 0.9 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.8 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 4.0 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.4 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 4.0 | GO:0045121 | membrane raft(GO:0045121) |
0.0 | 0.6 | GO:0031904 | endosome lumen(GO:0031904) |
0.0 | 0.3 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.3 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 0.5 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 1.1 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 0.7 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.4 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 0.1 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 4.4 | GO:0019770 | IgG receptor activity(GO:0019770) |
1.1 | 5.3 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
1.0 | 67.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
1.0 | 3.8 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
0.9 | 2.6 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.7 | 2.9 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.6 | 2.5 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
0.5 | 32.5 | GO:0030507 | spectrin binding(GO:0030507) |
0.4 | 2.7 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.4 | 13.0 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.4 | 6.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.4 | 2.3 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) |
0.4 | 10.3 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
0.4 | 4.9 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.3 | 8.2 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
0.3 | 1.0 | GO:0090555 | phosphatidylethanolamine-translocating ATPase activity(GO:0090555) |
0.3 | 1.3 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
0.3 | 4.4 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.3 | 0.9 | GO:1990254 | keratin filament binding(GO:1990254) |
0.3 | 2.7 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.3 | 1.3 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
0.3 | 3.4 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
0.3 | 0.8 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
0.3 | 0.8 | GO:0015265 | urea channel activity(GO:0015265) |
0.2 | 7.3 | GO:0001968 | fibronectin binding(GO:0001968) |
0.2 | 1.4 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.2 | 2.1 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
0.2 | 1.1 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
0.2 | 1.1 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
0.2 | 1.3 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
0.2 | 0.6 | GO:0017098 | sulfonylurea receptor binding(GO:0017098) |
0.2 | 1.1 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.2 | 2.7 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.2 | 5.4 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.1 | 5.0 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.1 | 0.4 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
0.1 | 0.6 | GO:0005148 | prolactin receptor binding(GO:0005148) |
0.1 | 3.6 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.1 | 4.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.1 | 0.9 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.1 | 3.5 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.1 | 5.1 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.1 | 0.4 | GO:0032093 | SAM domain binding(GO:0032093) |
0.1 | 0.5 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.1 | 2.6 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.1 | 0.6 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.1 | 3.4 | GO:0023023 | MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026) |
0.1 | 4.0 | GO:0015248 | sterol transporter activity(GO:0015248) |
0.1 | 4.7 | GO:0070840 | dynein complex binding(GO:0070840) |
0.1 | 0.8 | GO:0030345 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
0.1 | 21.5 | GO:0051015 | actin filament binding(GO:0051015) |
0.1 | 3.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.1 | 2.6 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.1 | 1.5 | GO:0043495 | protein anchor(GO:0043495) |
0.1 | 3.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.1 | 0.3 | GO:0070119 | ciliary neurotrophic factor binding(GO:0070119) |
0.1 | 5.8 | GO:0070888 | E-box binding(GO:0070888) |
0.1 | 0.8 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.1 | 1.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 2.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.1 | 3.4 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.1 | 0.4 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.1 | 1.3 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.1 | 0.6 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.1 | 0.4 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.1 | 1.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.1 | 0.4 | GO:0017002 | activin-activated receptor activity(GO:0017002) BMP receptor activity(GO:0098821) |
0.1 | 0.7 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
0.1 | 0.3 | GO:0004803 | transposase activity(GO:0004803) |
0.1 | 0.7 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.1 | 1.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.1 | 0.8 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.0 | 9.3 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
0.0 | 0.1 | GO:0019166 | 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.0 | 7.9 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.4 | GO:0004969 | histamine receptor activity(GO:0004969) |
0.0 | 0.5 | GO:0003720 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
0.0 | 8.7 | GO:0003823 | antigen binding(GO:0003823) |
0.0 | 2.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.6 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 11.3 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.3 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.0 | 1.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 2.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.6 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
0.0 | 2.3 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.6 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.3 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
0.0 | 0.7 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 3.3 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
0.0 | 0.5 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 1.0 | GO:0008066 | glutamate receptor activity(GO:0008066) |
0.0 | 0.2 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
0.0 | 0.4 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.0 | 0.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.1 | GO:0015639 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.0 | 1.0 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 0.6 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 0.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 4.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 4.7 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 1.0 | GO:0004177 | aminopeptidase activity(GO:0004177) |
0.0 | 0.1 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
0.0 | 1.5 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.1 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.0 | 0.9 | GO:0008374 | O-acyltransferase activity(GO:0008374) |
0.0 | 1.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.0 | 0.5 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.3 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 0.0 | GO:0004773 | steryl-sulfatase activity(GO:0004773) |
0.0 | 1.3 | GO:0008013 | beta-catenin binding(GO:0008013) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 9.7 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
0.1 | 2.1 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
0.1 | 8.5 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
0.1 | 2.5 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
0.1 | 2.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.1 | 2.7 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.1 | 11.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 3.5 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
0.1 | 0.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
0.1 | 1.4 | PID IFNG PATHWAY | IFN-gamma pathway |
0.1 | 4.3 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 2.0 | PID IL23 PATHWAY | IL23-mediated signaling events |
0.0 | 3.5 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
0.0 | 1.3 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
0.0 | 0.6 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 0.4 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 7.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 1.3 | PID LKB1 PATHWAY | LKB1 signaling events |
0.0 | 0.3 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 0.4 | PID ALK1 PATHWAY | ALK1 signaling events |
0.0 | 0.6 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 0.3 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 5.7 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.3 | 6.1 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
0.2 | 3.6 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.1 | 3.2 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
0.1 | 5.7 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 1.4 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.1 | 2.3 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
0.1 | 3.5 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.1 | 12.1 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
0.1 | 3.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
0.1 | 3.4 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
0.1 | 1.0 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
0.1 | 2.5 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
0.1 | 2.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
0.1 | 5.0 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.1 | 0.8 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.1 | 2.1 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
0.1 | 1.2 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
0.1 | 1.0 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.1 | 0.6 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
0.0 | 1.2 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.0 | 0.8 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.0 | 0.6 | REACTOME CTLA4 INHIBITORY SIGNALING | Genes involved in CTLA4 inhibitory signaling |
0.0 | 0.4 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
0.0 | 1.2 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.7 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 4.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.7 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.0 | 1.0 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
0.0 | 1.9 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.0 | 0.5 | REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | Genes involved in Glucagon signaling in metabolic regulation |
0.0 | 0.2 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
0.0 | 0.3 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
0.0 | 1.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 0.3 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
0.0 | 0.6 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.3 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |