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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SIX5_SMARCC2_HCFC1

Z-value: 5.71

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Transcription factors associated with SIX5_SMARCC2_HCFC1

Gene Symbol Gene ID Gene Info
ENSG00000177045.10 SIX5
ENSG00000139613.12 SMARCC2
ENSG00000172534.14 HCFC1

Activity-expression correlation:

Activity profile of SIX5_SMARCC2_HCFC1 motif

Sorted Z-values of SIX5_SMARCC2_HCFC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX5_SMARCC2_HCFC1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_151057880 47.45 ENST00000485972.6
cyclin dependent kinase 5
chr3_+_184174846 47.17 ENST00000427072.5
ENST00000411763.6
ENST00000292807.9
ENST00000448139.5
ENST00000455925.1
adaptor related protein complex 2 subunit mu 1
chr7_-_151057848 46.83 ENST00000297518.4
cyclin dependent kinase 5
chr15_+_40161003 39.03 ENST00000412359.7
ENST00000287598.11
BUB1 mitotic checkpoint serine/threonine kinase B
chr11_-_83286328 38.55 ENST00000525503.5
coiled-coil domain containing 90B
chr11_-_83285965 37.26 ENST00000529073.5
ENST00000529611.5
coiled-coil domain containing 90B
chr19_-_46850766 36.31 ENST00000601649.1
ENST00000599990.5
ENST00000352203.8
adaptor related protein complex 2 subunit sigma 1
chr11_-_83286377 35.92 ENST00000455220.6
ENST00000529689.5
coiled-coil domain containing 90B
chrX_-_108091520 34.20 ENST00000340200.5
ENST00000217958.8
ENST00000372296.5
ENST00000372295.5
ENST00000361815.9
proteasome 26S subunit, non-ATPase 10
chr19_-_46850825 31.76 ENST00000593442.5
ENST00000263270.11
adaptor related protein complex 2 subunit sigma 1
chr14_+_77457861 30.55 ENST00000555133.5
activator of HSP90 ATPase activity 1
chr11_+_61792878 30.01 ENST00000305885.3
ENST00000535723.1
flap structure-specific endonuclease 1
chr2_+_171687457 29.46 ENST00000397119.8
ENST00000410079.7
ENST00000438879.5
dynein cytoplasmic 1 intermediate chain 2
chr2_+_171687672 28.87 ENST00000409197.5
ENST00000456808.5
ENST00000409317.5
ENST00000409773.5
ENST00000411953.5
ENST00000409453.5
dynein cytoplasmic 1 intermediate chain 2
chr2_+_63589135 28.15 ENST00000432309.6
malate dehydrogenase 1
chr2_+_171687409 27.16 ENST00000452242.5
ENST00000340296.8
dynein cytoplasmic 1 intermediate chain 2
chr22_+_29767351 26.28 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr22_-_41286168 25.97 ENST00000356244.8
Ran GTPase activating protein 1
chr2_+_63588953 25.80 ENST00000409908.5
ENST00000442225.5
ENST00000233114.13
ENST00000539945.7
ENST00000409476.5
ENST00000436321.5
malate dehydrogenase 1
chr7_-_133082032 25.68 ENST00000448878.6
ENST00000262570.10
coiled-coil-helix-coiled-coil-helix domain containing 3
chr19_-_47048559 25.38 ENST00000253047.7
transmembrane protein 160
chr1_-_25906457 25.33 ENST00000426559.6
stathmin 1
chr2_+_171687501 24.82 ENST00000508530.5
dynein cytoplasmic 1 intermediate chain 2
chr8_+_109334317 24.25 ENST00000521662.5
ENST00000520147.5
ENST00000521688.6
ENY2 transcription and export complex 2 subunit
chr14_+_77458032 24.14 ENST00000535854.6
ENST00000555517.1
ENST00000216479.8
activator of HSP90 ATPase activity 1
chr6_-_5004004 23.56 ENST00000319533.9
ENST00000380051.7
ENST00000618533.4
ribonuclease P/MRP subunit p40
chr1_+_155308748 23.47 ENST00000611010.4
ENST00000447866.5
ENST00000368356.9
ENST00000467076.5
ENST00000491013.5
ENST00000356657.10
farnesyl diphosphate synthase
chr6_+_31666128 22.58 ENST00000375865.6
ENST00000375866.2
casein kinase 2 beta
chr6_-_5003604 22.43 ENST00000464646.1
ribonuclease P/MRP subunit p40
chr10_-_102502702 22.42 ENST00000369905.9
actin related protein 1A
chr10_-_102502669 22.33 ENST00000487599.1
actin related protein 1A
chr11_-_134253248 22.31 ENST00000392595.6
ENST00000352327.5
ENST00000341541.8
ENST00000392594.7
thymocyte nuclear protein 1
chr1_+_155308930 21.90 ENST00000465559.5
ENST00000612683.1
farnesyl diphosphate synthase
chr3_+_133805789 21.72 ENST00000678299.1
SRP receptor subunit beta
chr13_-_31161927 21.26 ENST00000380405.7
heat shock protein family H (Hsp110) member 1
chr10_+_123154414 21.21 ENST00000368858.9
BUB3 mitotic checkpoint protein
chr11_+_16738614 20.59 ENST00000524439.5
ENST00000228136.9
ENST00000528634.5
ENST00000525684.1
chromosome 11 open reading frame 58
chr1_+_224356852 20.49 ENST00000366858.7
ENST00000366857.9
ENST00000465271.6
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chr20_+_64063105 20.02 ENST00000395053.7
ENST00000343484.10
ENST00000339217.8
transcription elongation factor A2
chr1_+_156767526 19.65 ENST00000271526.9
proline rich mitotic checkpoint control factor
chr11_+_114439424 19.27 ENST00000544196.5
ENST00000265881.10
ENST00000539754.5
ENST00000539275.5
RNA exonuclease 2
chr3_-_98523013 19.20 ENST00000394181.6
ENST00000508902.5
ENST00000394180.6
claudin domain containing 1
chr8_-_73972248 18.95 ENST00000519082.5
elongin C
chr14_+_96797304 18.87 ENST00000553683.2
ENST00000680538.1
ENST00000681195.1
ENST00000679727.1
ENST00000680509.1
ENST00000557222.6
ENST00000680683.1
ENST00000680335.1
ENST00000216639.8
ENST00000679736.1
ENST00000681176.1
ENST00000557352.2
ENST00000679903.1
ENST00000681419.1
ENST00000680849.1
ENST00000681493.1
ENST00000679770.1
ENST00000681355.1
ENST00000681344.1
VRK serine/threonine kinase 1
chr1_-_25906931 18.53 ENST00000357865.6
stathmin 1
chr16_+_53703963 18.39 ENST00000636218.1
ENST00000637001.1
ENST00000471389.6
ENST00000637969.1
ENST00000640179.1
FTO alpha-ketoglutarate dependent dioxygenase
chr3_-_98522869 18.33 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
claudin domain containing 1
chr20_-_50115935 18.29 ENST00000340309.7
ENST00000415862.6
ENST00000371677.7
ubiquitin conjugating enzyme E2 V1
chr17_-_49414802 18.08 ENST00000511832.6
ENST00000419140.7
ENST00000617874.5
prohibitin
chr5_-_176388629 18.04 ENST00000619979.4
ENST00000621444.4
NOP16 nucleolar protein
chr6_+_31666056 18.03 ENST00000375882.7
ENST00000375880.6
casein kinase 2 beta
novel protein
chr3_-_98522514 17.94 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr20_+_31739260 17.82 ENST00000340513.4
ENST00000300403.11
TPX2 microtubule nucleation factor
chr19_-_2456924 17.75 ENST00000325327.4
lamin B2
chr1_+_156054761 17.59 ENST00000368305.9
ENST00000368304.9
ENST00000368302.3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr22_-_41285868 17.49 ENST00000422838.1
ENST00000405486.5
Ran GTPase activating protein 1
chr17_-_49414871 16.99 ENST00000504124.6
ENST00000300408.8
ENST00000614445.5
prohibitin
chr19_+_6361743 16.98 ENST00000597326.6
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr17_-_48101087 16.96 ENST00000393408.7
chromobox 1
chr12_+_56152579 16.79 ENST00000551834.5
ENST00000552568.5
myosin light chain 6B
chr17_-_48101379 16.73 ENST00000581003.5
ENST00000225603.9
chromobox 1
chr13_-_31161890 16.54 ENST00000320027.10
heat shock protein family H (Hsp110) member 1
chr11_+_114439515 16.53 ENST00000539119.5
RNA exonuclease 2
chr20_-_34303345 16.42 ENST00000217426.7
adenosylhomocysteinase
chr19_-_41959266 16.39 ENST00000600292.5
ENST00000601078.5
ENST00000601891.5
ENST00000222008.11
Rab acceptor 1
chr4_+_1721470 16.35 ENST00000612220.5
ENST00000313288.9
transforming acidic coiled-coil containing protein 3
chr1_+_47333774 16.35 ENST00000371873.10
cytidine/uridine monophosphate kinase 1
chr12_-_56316002 16.16 ENST00000547423.5
ENST00000548360.1
ENST00000551475.5
novel protein
canopy FGF signaling regulator 2
chr2_-_202911621 16.10 ENST00000261015.5
WD repeat domain 12
chr1_-_156741067 15.92 ENST00000361531.6
ENST00000412846.5
mitochondrial ribosomal protein L24
chr6_-_38703066 15.68 ENST00000373365.5
glyoxalase I
chr19_-_54115271 15.67 ENST00000391757.1
TCF3 fusion partner
chr15_-_52568832 15.65 ENST00000561650.5
cAMP regulated phosphoprotein 19
chr10_+_123154364 15.58 ENST00000368859.6
ENST00000368865.9
BUB3 mitotic checkpoint protein
chr15_-_52569197 15.43 ENST00000563277.5
ENST00000566423.5
cAMP regulated phosphoprotein 19
chr12_-_56315890 15.25 ENST00000551286.1
ENST00000549318.5
canopy FGF signaling regulator 2
novel protein
chr5_-_62403506 15.22 ENST00000680062.1
DIMT1 rRNA methyltransferase and ribosome maturation factor
chr12_+_32679200 15.00 ENST00000452533.6
ENST00000414834.6
dynamin 1 like
chr8_-_73972223 14.99 ENST00000522337.5
elongin C
chr13_-_31162341 14.92 ENST00000445273.6
ENST00000630972.2
heat shock protein family H (Hsp110) member 1
chr12_+_32679269 14.86 ENST00000358214.9
ENST00000553257.6
ENST00000549701.6
ENST00000266481.10
ENST00000551476.5
ENST00000550154.5
ENST00000547312.5
ENST00000381000.8
ENST00000548750.5
dynamin 1 like
chr6_+_43014103 14.84 ENST00000244670.12
ENST00000326974.9
ENST00000332245.9
kelch domain containing 3
chr20_-_49188360 14.74 ENST00000371828.7
ENST00000340954.11
ENST00000347458.9
ENST00000360426.8
ENST00000371792.5
ENST00000371802.5
ENST00000437404.2
staufen double-stranded RNA binding protein 1
chr14_-_24232332 14.53 ENST00000534348.5
ENST00000524927.1
ENST00000250495.10
NEDD8-MDP1 readthrough
NEDD8 ubiquitin like modifier
chr11_+_74949241 14.49 ENST00000610881.4
ENST00000530257.5
ENST00000526361.1
ENST00000532972.5
ENST00000263672.11
signal peptidase complex subunit 2
chr20_-_49188323 14.45 ENST00000371856.7
staufen double-stranded RNA binding protein 1
chr1_-_25906411 14.39 ENST00000455785.7
stathmin 1
chr2_-_218270099 14.39 ENST00000248450.9
ENST00000444053.5
angio associated migratory cell protein
chr19_-_1095261 14.34 ENST00000585838.2
ENST00000586746.5
ENST00000619917.4
ENST00000615234.5
ENST00000612655.4
RNA polymerase II, I and III subunit E
chr1_-_156741124 14.30 ENST00000368211.8
mitochondrial ribosomal protein L24
chr19_+_12806550 14.30 ENST00000221486.6
ribonuclease H2 subunit A
chr1_+_44739825 14.23 ENST00000372224.9
kinesin family member 2C
chr14_+_24232892 14.19 ENST00000420554.6
guanosine monophosphate reductase 2
chr1_-_36149450 14.17 ENST00000373163.5
trafficking protein particle complex 3
chr10_+_102132994 13.95 ENST00000413464.6
ENST00000278070.7
PPARG related coactivator 1
chr3_+_170222412 13.88 ENST00000295797.5
protein kinase C iota
chr11_-_47426216 13.82 ENST00000530651.5
ENST00000524447.6
ENST00000531051.6
ENST00000526993.1
ENST00000602866.5
proteasome 26S subunit, ATPase 3
chrX_+_155881306 13.75 ENST00000286448.12
ENST00000262640.11
ENST00000460621.6
vesicle associated membrane protein 7
chr6_+_30908178 13.72 ENST00000259895.9
ENST00000376316.5
general transcription factor IIH subunit 4
chr3_+_159273235 13.58 ENST00000638749.1
IQCJ-SCHIP1 readthrough
chr5_-_132777229 13.57 ENST00000378721.8
ENST00000378719.7
ENST00000378701.5
septin 8
chr1_+_43974902 13.57 ENST00000532642.5
ENST00000236067.8
ENST00000471859.6
ENST00000472174.7
ATPase H+ transporting V0 subunit b
chr5_+_86617967 13.54 ENST00000515763.1
cytochrome c oxidase subunit 7C
chrX_-_49123721 13.44 ENST00000156109.7
G-patch domain and KOW motifs
chr5_-_132777215 13.42 ENST00000458488.2
septin 8
chr19_-_54115626 13.41 ENST00000391759.6
TCF3 fusion partner
chr12_+_56152439 13.36 ENST00000550443.5
myosin light chain 6B
chr14_+_24232921 13.31 ENST00000557854.5
ENST00000399440.7
ENST00000559104.5
ENST00000456667.7
guanosine monophosphate reductase 2
chr6_-_43014254 13.31 ENST00000642748.1
male-enhanced antigen 1
chr19_+_17305801 13.30 ENST00000602206.1
ENST00000252602.2
mitochondrial ribosomal protein L34
chr9_+_113275642 13.27 ENST00000374199.9
ENST00000374198.5
pre-mRNA processing factor 4
chr6_-_110179702 13.27 ENST00000392587.6
WASP family member 1
chr15_-_52569126 13.25 ENST00000569723.5
ENST00000567669.5
ENST00000569281.6
ENST00000563566.5
ENST00000567830.1
cAMP regulated phosphoprotein 19
chr14_-_22929356 13.22 ENST00000397440.8
ENST00000627278.1
ENST00000421938.2
ENST00000324366.13
ENST00000554867.5
ENST00000556616.5
ENST00000216350.12
ENST00000553550.5
ENST00000397441.6
ENST00000553897.5
protein arginine methyltransferase 5
chr19_+_34734155 13.19 ENST00000599244.5
ENST00000392232.7
ENST00000492450.3
ENST00000595708.5
ENST00000593781.5
zinc finger protein 181
chr6_-_43013913 13.07 ENST00000244711.4
ENST00000643776.1
male-enhanced antigen 1
chr11_-_47426419 13.03 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
proteasome 26S subunit, ATPase 3
chr2_-_99336306 13.01 ENST00000264255.8
ENST00000409434.5
ENST00000434323.5
thioredoxin domain containing 9
chr8_-_73972106 12.95 ENST00000284811.12
elongin C
chr7_-_101245056 12.92 ENST00000223136.5
fission, mitochondrial 1
chr6_-_110179995 12.80 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr14_-_67674583 12.67 ENST00000554659.6
vesicle transport through interaction with t-SNAREs 1B
chr3_-_167734915 12.58 ENST00000497056.6
ENST00000473645.6
programmed cell death 10
chr5_+_178859924 12.58 ENST00000322434.8
zinc finger protein 354B
chr2_-_169573766 12.58 ENST00000438035.5
ENST00000453929.6
FAST kinase domains 1
chr16_+_4624811 12.54 ENST00000415496.5
ENST00000262370.12
ENST00000587747.5
ENST00000399577.9
ENST00000588994.5
ENST00000586183.5
mahogunin ring finger 1
chr1_-_10472475 12.52 ENST00000377036.2
ENST00000377038.8
DNA fragmentation factor subunit alpha
chr2_+_231781669 12.47 ENST00000410024.5
ENST00000611614.4
ENST00000409295.5
ENST00000409091.5
COP9 signalosome subunit 7B
chr12_+_93467506 12.35 ENST00000549982.6
ENST00000552217.6
ENST00000393128.8
ENST00000547098.5
mitochondrial ribosomal protein L42
chr12_+_56104527 12.34 ENST00000552766.5
ENST00000303305.11
proliferation-associated 2G4
chr19_+_36214602 12.30 ENST00000456324.5
zinc finger protein 146
chr15_-_52568960 12.27 ENST00000564163.5
ENST00000249822.9
cAMP regulated phosphoprotein 19
chr17_-_42798680 12.26 ENST00000328434.8
cytochrome c oxidase assembly factor 3
chr5_-_176388563 12.13 ENST00000509257.1
ENST00000616685.1
ENST00000614830.5
NOP16 nucleolar protein
chrX_-_119852948 12.10 ENST00000276201.7
ENST00000345865.6
UPF3B regulator of nonsense mediated mRNA decay
chr10_+_110225955 12.07 ENST00000239007.11
MAX interactor 1, dimerization protein
chr12_-_56315952 12.07 ENST00000273308.9
canopy FGF signaling regulator 2
chr16_-_15055969 11.97 ENST00000566419.1
ENST00000568320.5
N-terminal asparagine amidase
chr2_-_231781268 11.95 ENST00000287600.9
ENST00000409772.5
phosphodiesterase 6D
chr8_-_63038788 11.94 ENST00000518113.2
ENST00000260118.7
ENST00000677482.1
gamma-glutamyl hydrolase
chr3_-_167734832 11.93 ENST00000464360.5
ENST00000492139.5
ENST00000471885.5
ENST00000392750.7
ENST00000470131.5
programmed cell death 10
chr7_-_101245032 11.89 ENST00000442303.1
fission, mitochondrial 1
chr5_-_132777866 11.85 ENST00000448933.5
septin 8
chr12_-_56752311 11.78 ENST00000338193.11
ENST00000550770.1
DNA primase subunit 1
chr6_-_110179623 11.75 ENST00000265601.7
ENST00000447287.5
ENST00000392589.6
ENST00000444391.5
WASP family member 1
chrX_+_77899440 11.74 ENST00000373335.4
ENST00000475465.1
ENST00000650309.2
ENST00000647835.1
cytochrome c oxidase subunit 7B
chr14_-_67695747 11.37 ENST00000553384.5
ENST00000381346.9
ENST00000557726.1
retinol dehydrogenase 11
chr17_-_21214122 11.36 ENST00000317635.6
transmembrane protein 11
chr19_+_17267469 11.23 ENST00000596335.5
ENST00000601436.5
ENST00000595632.5
BRISC and BRCA1 A complex member 1
chr1_-_36149464 11.18 ENST00000373166.8
ENST00000373159.1
ENST00000373162.5
ENST00000616074.4
ENST00000616395.4
trafficking protein particle complex 3
chr6_-_17706748 11.09 ENST00000613258.4
ENST00000537253.5
nucleoporin 153
chr19_+_3185911 11.06 ENST00000246117.9
ENST00000588428.5
nicalin
chr5_+_5422665 11.06 ENST00000296564.9
interactor of little elongation complex ELL subunit 1
chr18_+_62715526 11.06 ENST00000262719.10
PH domain and leucine rich repeat protein phosphatase 1
chr11_+_60914139 11.06 ENST00000227525.8
transmembrane protein 109
chr7_+_135557904 11.05 ENST00000285968.11
nucleoporin 205
chr19_+_17267376 11.02 ENST00000447614.6
ENST00000359435.8
ENST00000599474.5
ENST00000599057.5
ENST00000598188.6
ENST00000601043.5
BRISC and BRCA1 A complex member 1
chr8_-_98117110 10.93 ENST00000520507.5
reactive intermediate imine deaminase A homolog
chr3_+_184299198 10.89 ENST00000417952.5
ENST00000310118.9
proteasome 26S subunit, non-ATPase 2
chr4_+_173370908 10.89 ENST00000296504.4
Sin3A associated protein 30
chr11_-_60906564 10.81 ENST00000541371.5
ENST00000227524.9
pre-mRNA processing factor 19
chr1_-_67430320 10.78 ENST00000370990.5
SERPINE1 mRNA binding protein 1
chr3_-_167734510 10.74 ENST00000475915.6
ENST00000462725.6
ENST00000461494.5
programmed cell death 10
chr14_+_101964561 10.67 ENST00000643508.2
ENST00000680137.1
ENST00000644881.2
ENST00000645149.2
ENST00000681574.1
ENST00000360184.10
ENST00000679720.1
ENST00000645114.2
dynein cytoplasmic 1 heavy chain 1
chr2_-_168890368 10.65 ENST00000282074.7
SPC25 component of NDC80 kinetochore complex
chr17_-_41918944 10.65 ENST00000352035.7
ENST00000590770.5
ENST00000590151.5
ATP citrate lyase
chr1_-_53838276 10.65 ENST00000371429.4
NDC1 transmembrane nucleoporin
chr14_+_24232612 10.61 ENST00000560139.5
ENST00000559910.5
ENST00000348719.11
guanosine monophosphate reductase 2
chr6_-_17706852 10.59 ENST00000262077.3
nucleoporin 153
chr1_+_37692506 10.59 ENST00000373055.6
cell division cycle associated 8
chr12_+_752551 10.57 ENST00000315939.11
ENST00000340908.9
ENST00000535572.5
WNK lysine deficient protein kinase 1
chr21_-_33915762 10.54 ENST00000290299.7
ATP synthase peripheral stalk subunit OSCP
chr19_+_6361782 10.49 ENST00000596149.5
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr1_-_67430412 10.46 ENST00000370994.8
SERPINE1 mRNA binding protein 1
chr12_-_56752366 10.43 ENST00000672280.1
DNA primase subunit 1
chr1_+_37692463 10.41 ENST00000327331.2
cell division cycle associated 8
chr10_+_92591733 10.35 ENST00000676647.1
kinesin family member 11
chr5_+_86617919 10.24 ENST00000247655.4
ENST00000509578.1
cytochrome c oxidase subunit 7C
chrX_+_47190836 10.21 ENST00000377351.8
ubiquitin like modifier activating enzyme 1
chr1_-_67430386 10.19 ENST00000370995.6
ENST00000361219.11
SERPINE1 mRNA binding protein 1
chr21_-_14383125 10.15 ENST00000285667.4
heat shock protein family A (Hsp70) member 13
chr12_+_12813316 10.15 ENST00000352940.8
ENST00000358007.7
ENST00000544400.1
DEAD-box helicase 47
chr1_+_38012706 10.15 ENST00000373014.5
UTP11 small subunit processome component
chr11_+_67606894 10.14 ENST00000532303.5
ENST00000532244.5
ENST00000528328.1
ENST00000322776.11
ENST00000529927.5
ENST00000532343.5
ENST00000415352.6
ENST00000533075.5
ENST00000529867.5
ENST00000530638.1
NADH:ubiquinone oxidoreductase core subunit V1
chr9_-_86282511 9.91 ENST00000375991.9
ENST00000326094.4
iron-sulfur cluster assembly 1
chr15_-_65185299 9.83 ENST00000300107.7
caseinolytic mitochondrial matrix peptidase chaperone subunit X
chr8_-_123042122 9.82 ENST00000405944.7
derlin 1
chr16_+_3024000 9.73 ENST00000326266.13
ENST00000574549.5
ENST00000575576.5
ENST00000253952.9
THO complex 6
chr1_-_25905989 9.70 ENST00000399728.5
stathmin 1
chr19_+_49851136 9.66 ENST00000391842.5
PTOV1 extended AT-hook containing adaptor protein
chr19_+_35745613 9.64 ENST00000222266.2
ENST00000587708.7
presenilin enhancer, gamma-secretase subunit
chr14_+_24232422 9.62 ENST00000620807.4
ENST00000355299.8
ENST00000559836.5
guanosine monophosphate reductase 2
chr8_-_73972164 9.62 ENST00000520210.1
ENST00000602840.5
ENST00000520242.6
elongin C
chr1_-_44355061 9.55 ENST00000649995.1
ENST00000457571.1
ENST00000372257.7
ENST00000452396.5
ERI1 exoribonuclease family member 3
chr3_-_50350710 9.55 ENST00000232501.8
NPR2 like, GATOR1 complex subunit
chr7_+_140696696 9.53 ENST00000247866.9
ENST00000464566.5
NADH:ubiquinone oxidoreductase subunit B2
chr19_+_35745590 9.50 ENST00000591949.1
presenilin enhancer, gamma-secretase subunit
chr18_-_36828939 9.38 ENST00000593035.5
ENST00000383056.7
ENST00000588909.1
ENST00000590337.5
ENST00000334295.9
tubulin polyglutamylase complex subunit 2
chr19_+_49851173 9.28 ENST00000599732.5
PTOV1 extended AT-hook containing adaptor protein
chr4_+_2536630 9.20 ENST00000637812.2
family with sequence similarity 193 member A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
13.5 94.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
12.4 49.4 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
12.3 110.3 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
11.4 34.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
10.9 54.7 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
9.3 27.8 GO:1902594 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
8.9 44.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
8.8 35.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
8.7 43.6 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
8.0 39.9 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
7.8 39.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
7.5 52.7 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
6.1 18.4 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
5.9 47.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
5.8 69.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
5.6 16.7 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
5.6 22.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
5.4 38.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
5.3 16.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
4.9 54.0 GO:0006108 malate metabolic process(GO:0006108)
4.6 59.9 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
4.6 13.8 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595) protein localization to vacuolar membrane(GO:1903778)
4.6 4.6 GO:0060623 regulation of chromosome condensation(GO:0060623)
4.4 115.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
4.3 43.5 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
4.3 60.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
4.2 29.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
3.9 15.8 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
3.9 15.7 GO:0009438 methylglyoxal metabolic process(GO:0009438)
3.5 7.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
3.3 16.5 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
3.3 13.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
3.3 13.2 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
3.3 69.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
3.3 16.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
3.3 13.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
3.2 9.7 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.1 18.9 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
3.1 34.2 GO:0042407 cristae formation(GO:0042407)
3.1 27.8 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
3.0 11.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
3.0 11.9 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
2.8 11.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
2.6 15.8 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
2.6 2.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
2.5 7.6 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
2.5 25.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
2.5 12.5 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
2.5 7.4 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
2.5 24.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
2.5 12.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
2.4 24.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
2.4 7.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
2.3 11.7 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
2.3 11.6 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
2.3 16.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
2.3 9.0 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
2.2 13.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
2.2 17.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
2.2 13.1 GO:0048254 snoRNA localization(GO:0048254)
2.1 4.2 GO:0006106 fumarate metabolic process(GO:0006106)
2.1 10.4 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
2.0 16.4 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
1.9 17.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.8 12.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
1.8 8.9 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
1.8 35.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.8 35.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
1.7 47.7 GO:0006144 purine nucleobase metabolic process(GO:0006144)
1.6 8.2 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
1.6 4.9 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
1.6 6.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
1.5 9.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.5 19.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
1.5 7.4 GO:0019348 dolichol metabolic process(GO:0019348)
1.5 16.2 GO:0048194 Golgi vesicle budding(GO:0048194)
1.4 55.1 GO:0071174 mitotic spindle checkpoint(GO:0071174)
1.4 5.7 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
1.4 5.7 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
1.4 107.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
1.4 5.6 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
1.4 23.7 GO:0007220 Notch receptor processing(GO:0007220)
1.4 4.1 GO:0021678 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
1.3 4.0 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
1.3 3.9 GO:0006172 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
1.3 5.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
1.2 14.4 GO:0042373 vitamin K metabolic process(GO:0042373)
1.2 21.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
1.2 7.2 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
1.1 19.5 GO:1902074 G1 to G0 transition(GO:0070314) response to salt(GO:1902074)
1.1 3.4 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
1.1 5.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.1 15.8 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
1.1 16.4 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
1.0 3.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
1.0 12.1 GO:0043248 proteasome assembly(GO:0043248)
1.0 13.9 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
1.0 4.8 GO:0006574 valine catabolic process(GO:0006574)
0.9 13.2 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.9 8.4 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.9 14.8 GO:0045116 protein neddylation(GO:0045116)
0.9 3.6 GO:0031627 telomeric loop formation(GO:0031627)
0.9 14.5 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.9 19.7 GO:0031167 rRNA methylation(GO:0031167)
0.9 3.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.9 2.6 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.9 4.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.8 49.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.8 12.5 GO:0000338 protein deneddylation(GO:0000338)
0.8 4.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.8 9.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.8 29.9 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.8 2.4 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.8 11.0 GO:0051382 kinetochore assembly(GO:0051382)
0.8 11.4 GO:0042574 retinal metabolic process(GO:0042574)
0.8 12.1 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.8 2.3 GO:0072229 proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.7 16.8 GO:0035855 megakaryocyte development(GO:0035855)
0.7 52.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.7 6.5 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
0.7 7.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.7 1.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.7 2.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.7 3.5 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.7 2.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of cell cycle checkpoint(GO:1901977) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) negative regulation of DNA damage checkpoint(GO:2000002)
0.7 9.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.7 2.7 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.7 4.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.7 16.3 GO:0006465 signal peptide processing(GO:0006465)
0.6 4.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.6 5.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.6 5.7 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.6 19.3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.6 3.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.6 20.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.6 4.9 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.6 26.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.6 66.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.6 8.3 GO:0017085 response to insecticide(GO:0017085)
0.6 6.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.6 5.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.6 2.9 GO:0052572 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.6 2.9 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.6 21.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.6 11.1 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.5 37.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.5 2.7 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5 16.9 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.5 6.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.5 3.0 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 4.0 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.5 1.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.5 1.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.5 1.4 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.5 30.2 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.5 3.2 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.5 3.6 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.5 4.1 GO:1905216 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.4 0.9 GO:0040031 snRNA modification(GO:0040031)
0.4 4.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.4 29.5 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.4 3.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.4 5.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.4 4.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.4 5.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.4 2.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.4 10.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 3.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.4 4.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084) DNA integration(GO:0015074)
0.4 3.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.4 10.1 GO:0001825 blastocyst formation(GO:0001825)
0.4 2.2 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.4 2.5 GO:0044036 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.4 1.4 GO:0030047 actin modification(GO:0030047)
0.4 2.8 GO:0072718 response to cisplatin(GO:0072718)
0.3 3.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.3 1.0 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3 14.7 GO:0070423 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.3 3.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.3 1.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.3 5.0 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.3 2.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.3 8.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 4.0 GO:0016180 snRNA processing(GO:0016180)
0.3 3.9 GO:0006449 regulation of translational termination(GO:0006449)
0.3 8.7 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.3 1.5 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3 1.8 GO:0044211 CTP salvage(GO:0044211)
0.3 5.2 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.3 4.0 GO:0000052 citrulline metabolic process(GO:0000052)
0.3 3.7 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.3 8.8 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.3 2.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 1.7 GO:0051012 microtubule sliding(GO:0051012)
0.3 0.8 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.3 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 2.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.3 7.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.3 3.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.3 3.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.2 0.7 GO:0007518 myoblast fate determination(GO:0007518)
0.2 13.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.2 2.6 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.2 2.8 GO:0098792 xenophagy(GO:0098792)
0.2 2.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.2 2.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.2 6.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 25.6 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.2 0.7 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.2 13.4 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.2 1.8 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 12.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.2 4.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.2 2.6 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 1.0 GO:0045176 apical protein localization(GO:0045176)
0.2 3.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 0.8 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.2 7.1 GO:0006101 citrate metabolic process(GO:0006101)
0.2 1.2 GO:1904526 regulation of microtubule binding(GO:1904526)
0.2 0.6 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 5.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 0.8 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.2 4.7 GO:1901661 quinone metabolic process(GO:1901661)
0.2 1.3 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.2 1.1 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.2 2.0 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 0.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.2 18.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.2 5.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 1.5 GO:0051683 establishment of Golgi localization(GO:0051683)
0.2 0.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.2 2.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 8.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 2.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 10.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 3.1 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.1 4.0 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 1.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 36.3 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 0.7 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 3.0 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 4.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.8 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.7 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.8 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 1.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 1.8 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.6 GO:1903286 regulation of potassium ion import(GO:1903286)
0.1 1.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 3.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.6 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
0.1 3.4 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.1 1.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 1.8 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.1 3.0 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 12.0 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 0.7 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 2.3 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 6.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 30.6 GO:0051260 protein homooligomerization(GO:0051260)
0.1 11.6 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.1 1.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 2.8 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.1 2.8 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.1 3.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 2.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 1.3 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 6.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.7 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 9.8 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.1 1.9 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 3.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 5.0 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 1.6 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 0.5 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 0.8 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 10.6 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.8 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 6.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 10.7 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 1.9 GO:0060976 coronary vasculature development(GO:0060976)
0.1 1.3 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.8 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0015847 putrescine transport(GO:0015847)
0.0 4.0 GO:0007338 single fertilization(GO:0007338)
0.0 1.0 GO:0009409 response to cold(GO:0009409)
0.0 4.9 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.0 3.6 GO:0045471 response to ethanol(GO:0045471)
0.0 0.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.7 GO:0015800 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.0 0.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 1.5 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.7 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.1 GO:0046851 negative regulation of tissue remodeling(GO:0034104) negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.0 1.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 3.8 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.6 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.3 GO:0033198 response to ATP(GO:0033198)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.4 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.1 GO:0043305 negative regulation of immunoglobulin production(GO:0002638) negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305)
0.0 0.2 GO:0048278 vesicle docking(GO:0048278)
0.0 0.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.4 GO:0009168 purine nucleoside monophosphate biosynthetic process(GO:0009127) purine ribonucleoside monophosphate biosynthetic process(GO:0009168)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
18.9 94.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
14.5 43.5 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
12.3 36.8 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
9.5 47.7 GO:1902560 GMP reductase complex(GO:1902560)
8.5 25.6 GO:0035370 UBC13-UEV1A complex(GO:0035370)
8.2 49.0 GO:0009368 endopeptidase Clp complex(GO:0009368)
7.5 52.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
7.5 44.7 GO:0002177 manchette(GO:0002177)
7.1 42.9 GO:0061617 MICOS complex(GO:0061617)
6.1 60.6 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
5.8 64.3 GO:0070449 elongin complex(GO:0070449)
5.6 33.7 GO:0001940 male pronucleus(GO:0001940)
5.2 83.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
5.1 112.7 GO:0036020 endolysosome membrane(GO:0036020)
5.1 30.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
4.9 126.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
4.4 13.3 GO:0071001 U4/U6 snRNP(GO:0071001)
4.4 17.6 GO:0071986 Ragulator complex(GO:0071986)
4.2 54.6 GO:0031209 SCAR complex(GO:0031209)
3.9 15.8 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
3.7 11.0 GO:0044611 nuclear pore inner ring(GO:0044611)
3.7 33.1 GO:0032133 chromosome passenger complex(GO:0032133)
3.6 10.7 GO:0031262 Ndc80 complex(GO:0031262)
3.5 39.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
3.5 21.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
3.5 13.9 GO:0020003 symbiont-containing vacuole(GO:0020003)
3.4 13.7 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
3.2 9.7 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
3.0 29.8 GO:0070552 BRISC complex(GO:0070552)
2.9 14.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
2.8 14.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
2.8 8.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
2.8 11.1 GO:0035363 histone locus body(GO:0035363)
2.7 16.1 GO:0070545 PeBoW complex(GO:0070545)
2.6 7.9 GO:0030689 Noc complex(GO:0030689)
2.6 23.7 GO:0070765 gamma-secretase complex(GO:0070765)
2.5 35.5 GO:0045277 respiratory chain complex IV(GO:0045277)
2.4 29.3 GO:0030008 TRAPP complex(GO:0030008)
2.4 19.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
2.4 7.1 GO:0018444 translation release factor complex(GO:0018444)
2.3 29.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
2.3 9.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
2.2 6.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
2.1 8.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
2.0 12.1 GO:0005816 spindle pole body(GO:0005816)
2.0 34.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
1.9 52.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.9 21.0 GO:0005638 lamin filament(GO:0005638)
1.8 16.3 GO:0005787 signal peptidase complex(GO:0005787)
1.8 17.8 GO:0043203 axon hillock(GO:0043203)
1.7 24.3 GO:0000124 SAGA complex(GO:0000124)
1.7 8.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.7 67.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.6 4.9 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.6 30.2 GO:0016461 unconventional myosin complex(GO:0016461)
1.5 29.1 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.5 4.6 GO:0071821 FANCM-MHF complex(GO:0071821)
1.5 16.6 GO:0005686 U2 snRNP(GO:0005686)
1.4 9.6 GO:1990130 Iml1 complex(GO:1990130)
1.4 13.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.3 8.9 GO:0005687 U4 snRNP(GO:0005687)
1.2 8.7 GO:0016272 prefoldin complex(GO:0016272)
1.2 15.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.2 4.6 GO:0071817 MMXD complex(GO:0071817)
1.1 9.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.1 4.3 GO:0033263 CORVET complex(GO:0033263)
1.0 28.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.0 3.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
1.0 3.1 GO:1902636 kinociliary basal body(GO:1902636)
1.0 10.0 GO:0005869 dynactin complex(GO:0005869)
1.0 30.8 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.9 5.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.9 14.0 GO:0034709 methylosome(GO:0034709)
0.9 13.8 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.8 4.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.8 6.6 GO:0070187 telosome(GO:0070187)
0.8 4.1 GO:0097513 myosin II filament(GO:0097513)
0.8 50.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.8 5.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.8 7.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.8 6.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.8 2.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.7 9.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.7 8.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.7 8.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.7 4.9 GO:0090661 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.7 2.8 GO:0071159 NF-kappaB complex(GO:0071159)
0.7 13.7 GO:0070822 Sin3-type complex(GO:0070822)
0.7 5.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.7 2.0 GO:0055087 Ski complex(GO:0055087)
0.6 4.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.6 14.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.6 13.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.6 3.0 GO:0043291 RAVE complex(GO:0043291)
0.6 35.0 GO:0005871 kinesin complex(GO:0005871)
0.6 14.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.6 6.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.6 5.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.6 6.6 GO:0071203 WASH complex(GO:0071203)
0.5 2.2 GO:0070876 SOSS complex(GO:0070876)
0.5 15.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.5 47.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.5 5.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.5 3.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.5 33.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.5 26.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.5 44.3 GO:0005643 nuclear pore(GO:0005643)
0.5 2.0 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.5 4.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.5 4.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.5 12.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.5 4.6 GO:0008278 cohesin complex(GO:0008278)
0.4 3.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.4 2.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.4 101.2 GO:0043209 myelin sheath(GO:0043209)
0.4 17.8 GO:0030684 preribosome(GO:0030684)
0.4 67.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 2.4 GO:0030891 VCB complex(GO:0030891)
0.4 4.0 GO:0032039 integrator complex(GO:0032039)
0.4 4.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.4 5.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.4 44.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.4 5.2 GO:0005685 U1 snRNP(GO:0005685)
0.4 3.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 1.1 GO:0070939 Dsl1p complex(GO:0070939)
0.4 2.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 3.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 1.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 1.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 16.6 GO:0031201 SNARE complex(GO:0031201)
0.3 1.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.3 17.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 19.4 GO:0005811 lipid particle(GO:0005811)
0.3 4.3 GO:0070469 respiratory chain(GO:0070469)
0.2 11.0 GO:0008180 COP9 signalosome(GO:0008180)
0.2 10.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 1.8 GO:0042382 paraspeckles(GO:0042382)
0.2 1.0 GO:0000439 core TFIIH complex(GO:0000439)
0.2 2.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 0.6 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.2 78.8 GO:0031966 mitochondrial membrane(GO:0031966)
0.2 8.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 4.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 7.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.7 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 1.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.8 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 2.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 4.8 GO:0031430 M band(GO:0031430)
0.1 2.7 GO:0032420 stereocilium(GO:0032420)
0.1 1.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 5.7 GO:0072686 mitotic spindle(GO:0072686)
0.1 14.8 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 11.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 7.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 3.4 GO:0002102 podosome(GO:0002102)
0.1 8.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 4.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 26.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 6.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 1.3 GO:0031527 filopodium membrane(GO:0031527)
0.1 2.9 GO:0005840 ribosome(GO:0005840)
0.1 9.6 GO:0070382 exocytic vesicle(GO:0070382)
0.1 3.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.5 GO:0016592 mediator complex(GO:0016592)
0.1 0.8 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 1.8 GO:0045095 keratin filament(GO:0045095)
0.0 1.4 GO:0036379 myofilament(GO:0036379)
0.0 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 99.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 16.5 GO:0009986 cell surface(GO:0009986)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 11.5 GO:0005730 nucleolus(GO:0005730)
0.0 1.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 16.0 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.3 GO:0000791 euchromatin(GO:0000791)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
31.4 94.3 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
10.8 54.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
9.5 47.7 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
8.7 43.6 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
8.0 111.4 GO:0045504 dynein heavy chain binding(GO:0045504)
7.4 22.2 GO:0003896 DNA primase activity(GO:0003896)
7.0 35.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
6.6 19.7 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
5.6 16.7 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
5.5 16.4 GO:0009041 uridylate kinase activity(GO:0009041)
5.2 31.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
5.0 60.6 GO:0004526 ribonuclease P activity(GO:0004526)
5.0 115.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
4.7 18.9 GO:0031493 nucleosomal histone binding(GO:0031493)
4.1 52.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
3.7 33.7 GO:1990226 histone methyltransferase binding(GO:1990226)
3.6 17.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
3.5 21.0 GO:0005047 signal recognition particle binding(GO:0005047)
3.5 27.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
3.4 30.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
3.3 13.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
2.8 8.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
2.8 19.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
2.6 15.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
2.5 15.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.5 22.2 GO:0030621 U4 snRNA binding(GO:0030621)
2.4 14.4 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
2.4 14.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.4 28.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
2.2 6.7 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
2.2 20.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
2.2 6.7 GO:0055100 adiponectin binding(GO:0055100)
2.1 8.5 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
2.0 8.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
1.9 13.6 GO:0000403 Y-form DNA binding(GO:0000403)
1.9 19.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
1.9 15.3 GO:0019237 centromeric DNA binding(GO:0019237)
1.8 54.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.8 10.7 GO:0004594 pantothenate kinase activity(GO:0004594)
1.7 10.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
1.7 89.3 GO:0008536 Ran GTPase binding(GO:0008536)
1.6 8.2 GO:1903135 cupric ion binding(GO:1903135)
1.6 6.5 GO:0070326 lipase binding(GO:0035473) very-low-density lipoprotein particle receptor binding(GO:0070326)
1.6 57.7 GO:0001671 ATPase activator activity(GO:0001671)
1.6 6.4 GO:0042809 vitamin D receptor binding(GO:0042809)
1.6 29.9 GO:0051400 BH domain binding(GO:0051400)
1.6 7.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
1.5 9.0 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.4 5.7 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
1.4 58.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
1.4 11.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.4 4.2 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.3 4.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.3 19.5 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
1.3 34.8 GO:0008198 ferrous iron binding(GO:0008198)
1.3 7.6 GO:0061665 SUMO ligase activity(GO:0061665)
1.2 9.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
1.2 7.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.2 35.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.2 6.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.1 3.4 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
1.1 41.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
1.1 15.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.0 3.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
1.0 5.1 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
1.0 5.1 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.9 49.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.9 20.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.9 7.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.9 10.7 GO:0045503 dynein light chain binding(GO:0045503)
0.9 9.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.8 21.9 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.8 7.6 GO:0070883 pre-miRNA binding(GO:0070883)
0.8 20.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.8 14.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.8 3.1 GO:0002046 opsin binding(GO:0002046)
0.7 28.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.7 34.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.7 4.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.7 13.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.7 2.8 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.7 4.8 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.7 13.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.6 6.5 GO:0017091 AU-rich element binding(GO:0017091)
0.6 14.2 GO:0008242 omega peptidase activity(GO:0008242)
0.6 5.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.6 8.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.6 6.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.6 4.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.6 21.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.6 18.1 GO:0070064 proline-rich region binding(GO:0070064)
0.6 8.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.6 9.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.6 4.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.6 2.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.5 12.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.5 19.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 42.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.5 6.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.5 13.2 GO:0004697 protein kinase C activity(GO:0004697)
0.5 3.5 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.5 2.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 3.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.5 51.1 GO:0003774 motor activity(GO:0003774)
0.4 3.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.4 5.0 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.4 21.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 17.9 GO:0019894 kinesin binding(GO:0019894)
0.4 3.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 2.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.4 79.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 10.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.4 7.4 GO:0030515 snoRNA binding(GO:0030515)
0.3 40.2 GO:0032947 protein complex scaffold(GO:0032947)
0.3 2.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 0.7 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.3 2.6 GO:0015288 porin activity(GO:0015288)
0.3 1.3 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.3 13.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 5.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 2.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 2.4 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.3 1.8 GO:0004849 uridine kinase activity(GO:0004849)
0.3 4.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 14.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 1.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 3.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.3 3.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 21.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 24.3 GO:0051082 unfolded protein binding(GO:0051082)
0.2 2.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 20.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.2 13.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 2.7 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.2 4.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 8.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 1.3 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) ubiquitin-protein transferase activator activity(GO:0097027)
0.2 2.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 0.6 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.2 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 7.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 5.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 5.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 2.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 1.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 5.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 58.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.2 1.7 GO:0031386 protein tag(GO:0031386)
0.2 4.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 23.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.2 5.1 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.2 8.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 4.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 7.5 GO:0004527 exonuclease activity(GO:0004527)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 2.9 GO:0005537 mannose binding(GO:0005537)
0.1 3.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 4.1 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 0.4 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 2.0 GO:0005522 profilin binding(GO:0005522)
0.1 4.6 GO:0050699 WW domain binding(GO:0050699)
0.1 1.1 GO:0034452 dynactin binding(GO:0034452)
0.1 0.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 26.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 4.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 2.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.8 GO:0001848 complement binding(GO:0001848)
0.1 15.5 GO:0051015 actin filament binding(GO:0051015)
0.1 3.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 3.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.1 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 4.7 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 2.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.1 GO:0019239 deaminase activity(GO:0019239)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.4 GO:0051117 ATPase binding(GO:0051117)
0.0 0.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 51.4 GO:0003723 RNA binding(GO:0003723)
0.0 1.5 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 3.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 5.5 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 3.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 2.4 GO:0005125 cytokine activity(GO:0005125)
0.0 4.5 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 66.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
2.6 124.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
1.9 43.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.8 47.2 PID ARF 3PATHWAY Arf1 pathway
1.6 39.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.0 51.2 PID AURORA A PATHWAY Aurora A signaling
0.9 47.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.8 23.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.7 39.5 PID IL1 PATHWAY IL1-mediated signaling events
0.7 28.1 PID AURORA B PATHWAY Aurora B signaling
0.7 12.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6 21.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.6 31.3 PID PLK1 PATHWAY PLK1 signaling events
0.5 16.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.5 10.0 PID MYC PATHWAY C-MYC pathway
0.5 18.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.4 48.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 7.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 19.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 1.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 16.2 PID P53 REGULATION PATHWAY p53 pathway
0.2 8.0 PID ATR PATHWAY ATR signaling pathway
0.2 10.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 24.4 PID P73PATHWAY p73 transcription factor network
0.2 13.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.2 PID BARD1 PATHWAY BARD1 signaling events
0.1 4.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 12.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 5.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 3.9 PID INSULIN PATHWAY Insulin Pathway
0.1 4.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 4.7 PID CDC42 PATHWAY CDC42 signaling events
0.1 2.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.9 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 131.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
3.1 85.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
3.0 6.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
2.6 73.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
2.6 54.8 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
2.0 47.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.8 23.7 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
1.7 13.9 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
1.7 161.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
1.5 108.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.4 46.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
1.3 20.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.2 18.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.1 100.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
1.1 43.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.9 13.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.9 44.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.9 16.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.9 14.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.9 58.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.9 11.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.9 13.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.9 16.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.8 13.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.8 16.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.8 6.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.8 27.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.8 5.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.8 15.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.8 9.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.8 8.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.8 21.9 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.8 63.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.7 27.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.7 19.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.7 15.4 REACTOME KINESINS Genes involved in Kinesins
0.6 18.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.6 1.9 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.6 1.3 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.6 15.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.6 15.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.6 20.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 9.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.6 8.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.6 18.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.5 26.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.5 4.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.5 16.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.4 8.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 10.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 30.6 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.3 11.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 14.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 20.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 8.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 4.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 1.5 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.3 7.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 5.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.2 3.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 26.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 3.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 8.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 5.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 9.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 3.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.2 10.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 5.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 22.9 REACTOME TRANSLATION Genes involved in Translation
0.1 4.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 4.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.1 3.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.4 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.1 2.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.6 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.3 REACTOME S PHASE Genes involved in S Phase
0.0 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 4.0 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)