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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SMAD1

Z-value: 8.58

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Transcription factors associated with SMAD1

Gene Symbol Gene ID Gene Info
ENSG00000170365.10 SMAD1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD1hg38_v1_chr4_+_145481845_145481871,
hg38_v1_chr4_+_145482761_145482820
-0.521.3e-16Click!

Activity profile of SMAD1 motif

Sorted Z-values of SMAD1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_105771405 147.99 ENST00000641136.1
ENST00000390551.6
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_105644790 124.35 ENST00000641095.1
ENST00000390545.3
immunoglobulin heavy constant gamma 2 (G2m marker)
chr14_-_105626066 112.60 ENST00000641978.1
ENST00000390543.3
immunoglobulin heavy constant gamma 4 (G4m marker)
chr6_+_33080445 89.61 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr22_+_22895368 85.51 ENST00000390321.2
immunoglobulin lambda constant 1
chr6_+_33075952 83.33 ENST00000418931.7
major histocompatibility complex, class II, DP beta 1
chr19_+_49335396 80.83 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr22_+_22899481 77.44 ENST00000390322.2
immunoglobulin lambda joining 2
chr14_-_105743032 72.21 ENST00000390548.6
ENST00000390549.6
ENST00000390542.6
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_107775951 71.76 ENST00000315660.8
ENST00000372384.6
ENST00000502650.1
ENST00000506724.1
TSC22 domain family member 3
chr22_+_22904850 62.61 ENST00000390324.2
immunoglobulin lambda joining 3
chr2_-_89160329 58.64 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr2_-_88992903 55.90 ENST00000495489.1
immunoglobulin kappa variable 1-8
chrX_-_107775740 54.24 ENST00000372383.9
TSC22 domain family member 3
chr2_+_90038848 49.00 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr6_-_33080710 48.57 ENST00000419277.5
major histocompatibility complex, class II, DP alpha 1
chr9_+_136980211 48.16 ENST00000444903.2
prostaglandin D2 synthase
chr4_-_1208825 45.62 ENST00000511679.5
ENST00000617421.4
spondin 2
chr14_-_106507476 40.26 ENST00000390621.3
immunoglobulin heavy variable 1-45
chr14_-_105708627 40.22 ENST00000641837.1
ENST00000390547.3
immunoglobulin heavy constant alpha 1
chr6_+_31615984 39.35 ENST00000376049.4
allograft inflammatory factor 1
chr11_+_1870252 38.37 ENST00000612798.4
lymphocyte specific protein 1
chr4_-_1172575 37.59 ENST00000290902.10
spondin 2
chr6_-_31272069 37.52 ENST00000415537.1
ENST00000376228.9
ENST00000383329.7
major histocompatibility complex, class I, C
chr21_-_44910630 37.51 ENST00000320216.10
ENST00000397852.5
integrin subunit beta 2
chr19_+_1067493 36.53 ENST00000586866.5
Rho GTPase activating protein 45
chr6_-_31582415 35.82 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr22_+_22697789 35.37 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr22_-_19525369 34.98 ENST00000403084.1
ENST00000413119.2
claudin 5
chr4_-_1173168 34.61 ENST00000514490.5
ENST00000431380.5
ENST00000503765.5
spondin 2
chr6_+_31615215 34.23 ENST00000337917.11
ENST00000376059.8
allograft inflammatory factor 1
chr11_+_1870150 34.14 ENST00000429923.5
ENST00000418975.1
ENST00000406638.6
lymphocyte specific protein 1
chr16_+_30472733 34.11 ENST00000356798.11
ENST00000433423.2
integrin subunit alpha L
chr18_-_50287816 33.37 ENST00000589548.6
ENST00000673786.1
CXXC finger protein 1
chr2_+_90069662 33.00 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_-_89040745 32.75 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr6_+_32637419 32.51 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr4_-_56656507 32.39 ENST00000381255.7
ENST00000317745.11
ENST00000555760.6
ENST00000556614.6
HOP homeobox
chr16_+_172869 31.83 ENST00000251595.11
ENST00000397806.1
ENST00000484216.1
hemoglobin subunit alpha 2
chr1_-_30757767 31.74 ENST00000294507.4
lysosomal protein transmembrane 5
chr13_+_30735523 31.71 ENST00000380490.5
arachidonate 5-lipoxygenase activating protein
chr12_-_14951106 31.49 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr19_+_1067144 31.42 ENST00000313093.7
Rho GTPase activating protein 45
chr12_-_108633864 30.89 ENST00000550948.2
selectin P ligand
chr9_+_136977496 30.71 ENST00000371625.8
ENST00000457950.5
prostaglandin D2 synthase
chr11_+_121590388 30.43 ENST00000527934.1
sortilin related receptor 1
chr22_+_22887780 29.94 ENST00000532223.2
ENST00000526893.6
ENST00000531372.1
immunoglobulin lambda like polypeptide 5
chr21_-_44920855 29.66 ENST00000397854.7
integrin subunit beta 2
chr19_+_45469841 29.66 ENST00000592811.5
ENST00000586615.5
FosB proto-oncogene, AP-1 transcription factor subunit
chr6_+_29942523 29.24 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr6_+_31587268 28.28 ENST00000396101.7
ENST00000490742.5
leukocyte specific transcript 1
chr19_+_1077394 27.97 ENST00000590577.2
Rho GTPase activating protein 45
chr14_-_105856183 27.74 ENST00000637539.2
ENST00000390559.6
immunoglobulin heavy constant mu
chr2_+_89862438 27.11 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr7_+_74209386 27.11 ENST00000344995.9
linker for activation of T cells family member 2
chr2_-_89143133 26.98 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr17_+_39927724 26.86 ENST00000377924.6
ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
leucine rich repeat containing 3C
novel transcript
chr11_+_2302119 26.67 ENST00000381121.7
tetraspanin 32
chr12_+_6946468 26.10 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr13_+_30713477 25.56 ENST00000617770.4
arachidonate 5-lipoxygenase activating protein
chr11_-_2301859 25.17 ENST00000456145.2
ENST00000381153.8
chromosome 11 open reading frame 21
chr2_+_89851723 24.99 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr14_-_105940235 24.93 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr1_+_27879638 24.92 ENST00000456990.1
thymocyte selection associated family member 2
chr2_-_88979016 24.62 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_238138661 24.46 ENST00000409223.2
kelch like family member 30
chr18_-_50287570 24.35 ENST00000586837.1
ENST00000412036.6
ENST00000589940.5
ENST00000587396.1
ENST00000591474.5
ENST00000285106.11
CXXC finger protein 1
chr2_+_68365274 24.31 ENST00000234313.8
pleckstrin
chr22_+_22734577 23.93 ENST00000390310.3
immunoglobulin lambda variable 2-18
chr2_-_89100352 23.78 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr19_+_41877267 23.65 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79a molecule
chr1_+_161215242 23.49 ENST00000367992.7
ENST00000289902.2
Fc fragment of IgE receptor Ig
chr11_-_5234475 23.44 ENST00000292901.7
ENST00000650601.1
ENST00000417377.1
hemoglobin subunit delta
chr22_+_22431949 23.14 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr2_-_136118142 23.00 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr17_-_64390852 22.85 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr17_-_82317589 22.81 ENST00000312648.8
CD7 molecule
chr6_+_32741382 22.74 ENST00000374940.4
major histocompatibility complex, class II, DQ alpha 2
chr22_+_22822658 22.36 ENST00000620395.2
immunoglobulin lambda variable 2-8
chr6_-_25042003 22.36 ENST00000510784.8
RHO family interacting cell polarization regulator 2
chr14_-_94390650 22.33 ENST00000449399.7
ENST00000404814.8
serpin family A member 1
chr17_-_82317523 22.32 ENST00000583376.1
ENST00000578509.1
ENST00000584284.5
ENST00000582480.1
CD7 molecule
chr16_+_3065297 22.13 ENST00000325568.9
interleukin 32
chr1_+_152663378 22.00 ENST00000368784.2
late cornified envelope 2D
chr16_+_3065311 21.76 ENST00000534507.5
ENST00000613483.4
ENST00000531965.5
ENST00000396887.7
interleukin 32
chr2_-_89010515 21.74 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr19_+_39406831 21.66 ENST00000597629.3
ENST00000594442.2
ENST00000594045.2
ZFP36 ring finger protein
chr14_-_95714088 21.62 ENST00000556450.5
TCL1 family AKT coactivator A
chr11_+_314010 21.56 ENST00000680699.1
ENST00000681938.1
ENST00000679380.1
ENST00000680938.1
ENST00000408968.4
ENST00000681180.1
ENST00000681426.1
ENST00000680696.1
interferon induced transmembrane protein 1
chr6_-_24877262 21.43 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr4_-_56656448 21.42 ENST00000553379.6
HOP homeobox
chr10_+_45374204 21.20 ENST00000374391.7
arachidonate 5-lipoxygenase
chr22_+_22758698 21.15 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr6_-_31357171 21.11 ENST00000412585.7
ENST00000434333.1
major histocompatibility complex, class I, B
chr6_+_30489501 21.07 ENST00000376630.5
major histocompatibility complex, class I, E
chr2_+_90159840 21.03 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr2_+_87338511 21.02 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr11_+_2301987 20.91 ENST00000612299.4
ENST00000182290.9
tetraspanin 32
chr3_-_41961989 20.83 ENST00000420927.5
ENST00000301831.9
ENST00000414606.1
unc-51 like kinase 4
chr2_+_90172802 20.76 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr7_+_74209989 20.75 ENST00000361082.7
ENST00000275635.11
ENST00000460943.6
ENST00000470709.1
linker for activation of T cells family member 2
chr14_-_95714146 20.60 ENST00000554012.5
TCL1 family AKT coactivator A
chr14_-_95714114 20.57 ENST00000402399.6
ENST00000555202.1
TCL1 family AKT coactivator A
chr22_-_37149900 20.48 ENST00000216223.10
interleukin 2 receptor subunit beta
chr3_-_121660892 20.37 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr1_-_161631152 20.29 ENST00000421702.3
ENST00000650385.1
Fc fragment of IgG receptor IIIb
chr20_-_23086316 20.26 ENST00000246006.5
CD93 molecule
chr11_+_1868673 20.22 ENST00000405957.6
lymphocyte specific protein 1
chr14_-_106658251 20.22 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr2_+_90234809 20.02 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr19_+_44914588 20.00 ENST00000592535.6
apolipoprotein C1
chr1_+_153357846 19.94 ENST00000368738.4
S100 calcium binding protein A9
chr2_-_86790825 19.81 ENST00000409781.1
ENST00000352580.7
CD8a molecule
chr6_+_32637396 19.81 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr16_+_30472700 19.75 ENST00000358164.9
integrin subunit alpha L
chr14_-_94390667 19.74 ENST00000557492.5
ENST00000355814.8
ENST00000437397.5
ENST00000448921.5
ENST00000393088.8
serpin family A member 1
chr22_+_36863091 19.73 ENST00000650698.1
neutrophil cytosolic factor 4
chr1_+_32274111 19.59 ENST00000619559.4
ENST00000461712.6
ENST00000373562.7
ENST00000477031.6
ENST00000373557.6
ENST00000333070.4
LCK proto-oncogene, Src family tyrosine kinase
chr1_-_202159977 19.42 ENST00000367279.8
protein tyrosine phosphatase non-receptor type 7
chr14_-_106185387 19.41 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr19_-_54280498 19.38 ENST00000391746.5
leukocyte immunoglobulin like receptor B2
chr10_+_38010617 19.29 ENST00000307441.13
ENST00000374618.7
ENST00000628825.2
ENST00000458705.6
ENST00000432900.7
ENST00000469037.2
zinc finger protein 33A
chr6_-_73452124 19.19 ENST00000680833.1
cyclic GMP-AMP synthase
chr14_+_22547495 19.07 ENST00000611116.2
T cell receptor alpha constant
chr5_-_150113344 18.97 ENST00000286301.7
ENST00000511344.1
colony stimulating factor 1 receptor
chr19_+_1067272 18.84 ENST00000590214.5
Rho GTPase activating protein 45
chr11_-_5227063 18.80 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr2_-_89320146 18.71 ENST00000498574.1
immunoglobulin kappa variable 1-39
chr11_+_308408 18.66 ENST00000399815.2
novel protein
chr11_+_2400488 18.56 ENST00000380996.9
ENST00000380992.5
ENST00000333256.11
ENST00000437110.5
ENST00000435795.5
tumor suppressing subtransferable candidate 4
chr2_-_86790900 18.50 ENST00000283635.8
CD8a molecule
chr14_-_106715166 18.49 ENST00000390633.2
immunoglobulin heavy variable 1-69
chr1_+_12019460 18.46 ENST00000235332.6
migration and invasion inhibitory protein
chr6_-_166956561 18.44 ENST00000366855.10
ribonuclease T2
chr19_-_35740535 18.42 ENST00000591748.1
IGF like family receptor 1
chr19_+_47309853 18.42 ENST00000355085.4
complement C5a receptor 1
chr16_+_3065348 18.36 ENST00000529699.5
ENST00000526464.6
ENST00000440815.7
ENST00000529550.5
interleukin 32
chr6_+_31586835 18.09 ENST00000211921.11
leukocyte specific transcript 1
chr22_+_22327298 18.09 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr14_-_94390614 18.07 ENST00000553327.5
ENST00000556955.5
ENST00000557118.5
ENST00000440909.5
serpin family A member 1
chr12_+_6789508 18.04 ENST00000011653.9
ENST00000541982.5
ENST00000539492.1
CD4 molecule
chr19_-_3801791 18.04 ENST00000590849.1
ENST00000395045.6
megakaryocyte-associated tyrosine kinase
chr7_-_150800320 17.96 ENST00000492607.5
ENST00000326442.10
ENST00000450753.2
transmembrane protein 176B
chr5_-_170297746 17.71 ENST00000046794.10
lymphocyte cytosolic protein 2
chr11_-_61917490 17.53 ENST00000394836.7
RAB3A interacting protein like 1
chr14_-_106422175 17.53 ENST00000390619.2
immunoglobulin heavy variable 4-39
chr9_+_136979042 17.49 ENST00000446677.2
prostaglandin D2 synthase
chr22_+_22792485 17.37 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr19_+_18173804 17.36 ENST00000407280.4
IFI30 lysosomal thiol reductase
chr14_-_106737547 17.28 ENST00000632209.1
immunoglobulin heavy variable 1-69-2
chr15_+_81299416 17.27 ENST00000558332.3
interleukin 16
chr12_+_6951345 17.23 ENST00000318974.14
ENST00000541698.5
ENST00000542462.1
protein tyrosine phosphatase non-receptor type 6
chr1_-_169711603 17.16 ENST00000236147.6
ENST00000650983.1
selectin L
chr19_-_51372640 17.11 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr15_+_81296913 17.10 ENST00000394652.6
interleukin 16
chr16_-_66552460 17.07 ENST00000678015.1
ENST00000569718.6
ENST00000678314.1
ENST00000562484.2
thymidine kinase 2
chr16_+_1240698 17.01 ENST00000561736.2
ENST00000338844.8
ENST00000461509.6
tryptase alpha/beta 1
chr12_+_120725796 16.88 ENST00000242592.9
ENST00000411593.2
acyl-CoA dehydrogenase short chain
chr10_+_80408503 16.74 ENST00000606162.6
peroxiredoxin like 2A
chr15_-_78944985 16.57 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
cathepsin H
chr15_-_21742799 16.52 ENST00000622410.2
novel protein, identical to IGHV4-4
chr3_+_88059231 16.49 ENST00000636215.2
zinc finger protein 654
chr3_-_50338226 16.46 ENST00000395126.7
Ras association domain family member 1
chr10_+_11165475 16.43 ENST00000609692.5
ENST00000354897.3
CUGBP Elav-like family member 2
chr19_-_51372269 16.43 ENST00000593572.5
ENST00000595157.1
natural killer cell granule protein 7
chr15_+_88638947 16.37 ENST00000559876.2
interferon stimulated exonuclease gene 20
chrX_+_71366290 16.31 ENST00000683782.1
ENST00000423759.6
TATA-box binding protein associated factor 1
chrX_-_107777038 16.30 ENST00000480691.2
ENST00000506081.5
ENST00000514426.1
TSC22 domain family member 3
chr18_+_79679775 16.29 ENST00000613122.5
ENST00000075430.11
CTD phosphatase subunit 1
chr22_+_22922594 16.26 ENST00000390331.3
immunoglobulin lambda constant 7
chr10_+_45374167 16.07 ENST00000542434.5
arachidonate 5-lipoxygenase
chr11_+_121576760 15.96 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr5_-_42825884 15.95 ENST00000506577.5
selenoprotein P
chr2_+_68774782 15.92 ENST00000409030.7
ENST00000409220.5
Rho GTPase activating protein 25
chr13_+_41457543 15.89 ENST00000379359.4
regulator of cell cycle
chr14_-_106025628 15.88 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr14_-_106277039 15.87 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr2_-_89213917 15.78 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr2_+_90082635 15.77 ENST00000483379.1
immunoglobulin kappa variable 1D-17
chr1_-_27635176 15.75 ENST00000374005.8
FGR proto-oncogene, Src family tyrosine kinase
chr9_-_134917872 15.74 ENST00000616356.4
ENST00000371806.4
ficolin 1
chr1_+_192575765 15.72 ENST00000469578.2
ENST00000367459.8
regulator of G protein signaling 1
chr19_+_8413270 15.70 ENST00000381035.8
ENST00000595142.5
ENST00000601724.5
ENST00000601283.5
ENST00000215555.7
ENST00000595213.1
membrane associated ring-CH-type finger 2
chr19_-_35908247 15.70 ENST00000585901.6
ENST00000544690.6
ENST00000424586.7
ENST00000262629.9
ENST00000589517.1
transmembrane immune signaling adaptor TYROBP
chr1_+_152675295 15.64 ENST00000368783.1
late cornified envelope 2C
chrX_+_47078330 15.60 ENST00000457380.5
regucalcin
chr6_-_166956537 15.60 ENST00000508775.6
ribonuclease T2
chr15_-_19988117 15.57 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr17_-_17972374 15.50 ENST00000318094.14
ENST00000540946.5
ENST00000379504.8
ENST00000542206.5
ENST00000395739.8
ENST00000581396.5
ENST00000535933.5
ENST00000579586.1
target of myb1 like 2 membrane trafficking protein
chr5_+_55102635 15.49 ENST00000274306.7
granzyme A
chr12_-_3873346 15.47 ENST00000427057.6
poly(ADP-ribose) polymerase family member 11
chr11_-_67437670 15.42 ENST00000326294.4
protein tyrosine phosphatase receptor type C associated protein
chr9_-_94639473 15.41 ENST00000375326.9
fructose-bisphosphatase 1
chr16_+_33802683 15.37 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr16_+_3065380 15.36 ENST00000551122.5
ENST00000548807.5
ENST00000528163.6
interleukin 32
chr10_-_133276836 15.32 ENST00000415217.7
ADAM metallopeptidase domain 8
chr15_-_21718245 15.29 ENST00000630556.1
novel gene identicle to IGHV1OR15-1
chr19_-_54364863 15.23 ENST00000348231.8
leukocyte associated immunoglobulin like receptor 1
chr14_-_105588322 15.20 ENST00000497872.4
ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chrX_-_153926220 15.06 ENST00000370016.5
Rho GTPase activating protein 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
18.6 149.0 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
15.5 46.4 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
13.7 137.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
13.7 68.5 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
13.7 1027.8 GO:0006910 phagocytosis, recognition(GO:0006910)
12.8 64.1 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
12.2 36.7 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
11.8 129.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
11.7 58.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
10.8 43.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
10.6 42.4 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
10.5 31.5 GO:0071461 cellular response to redox state(GO:0071461)
10.3 10.3 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
10.1 30.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
10.1 80.5 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
10.0 39.9 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
9.8 39.3 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
9.4 37.6 GO:0050902 leukocyte adhesive activation(GO:0050902)
9.3 46.3 GO:0072535 tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307)
9.2 27.5 GO:0030185 nitric oxide transport(GO:0030185)
9.0 36.2 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
9.0 9.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
8.9 26.7 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
8.9 8.9 GO:1903004 regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
8.9 26.6 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
8.6 25.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
8.4 67.4 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
8.3 24.8 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
8.1 32.4 GO:0036369 transcription factor catabolic process(GO:0036369)
8.1 32.3 GO:1903631 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
7.9 71.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
7.6 22.9 GO:0038178 complement component C5a signaling pathway(GO:0038178)
7.6 30.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
7.4 29.6 GO:1905224 clathrin-coated pit assembly(GO:1905224)
7.4 22.1 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
7.2 136.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
7.1 21.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
6.8 6.8 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
6.8 6.8 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
6.8 635.3 GO:0006958 complement activation, classical pathway(GO:0006958)
6.7 20.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
6.5 13.0 GO:0032661 regulation of interleukin-18 production(GO:0032661)
6.5 25.9 GO:0002357 defense response to tumor cell(GO:0002357)
6.5 45.2 GO:0070560 protein secretion by platelet(GO:0070560)
6.4 6.4 GO:0002442 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
6.2 24.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
6.2 24.7 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
6.1 12.3 GO:1905237 response to cyclosporin A(GO:1905237)
6.1 61.0 GO:2001300 lipoxin metabolic process(GO:2001300)
6.1 6.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
5.9 17.8 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
5.8 11.5 GO:0001812 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
5.7 22.8 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
5.6 39.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
5.5 16.6 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
5.5 16.4 GO:2000754 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
5.4 16.2 GO:0002818 intracellular defense response(GO:0002818)
5.4 16.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
5.3 37.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
5.3 15.9 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
5.2 20.8 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
5.2 5.2 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
5.2 31.0 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
5.1 106.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
5.0 5.0 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
4.9 4.9 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
4.9 4.9 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
4.9 4.9 GO:0010872 regulation of cholesterol esterification(GO:0010872)
4.9 14.6 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
4.8 24.1 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
4.5 17.9 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
4.4 22.0 GO:0044027 hypermethylation of CpG island(GO:0044027)
4.4 13.2 GO:0061011 hepatic duct development(GO:0061011)
4.4 13.2 GO:0051673 pore formation in membrane of other organism(GO:0035915) membrane disruption in other organism(GO:0051673)
4.3 17.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
4.3 4.3 GO:0060290 transdifferentiation(GO:0060290)
4.3 12.8 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
4.2 12.7 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
4.2 12.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
4.2 8.4 GO:0006258 UDP-glucose catabolic process(GO:0006258)
4.2 12.5 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
4.2 4.2 GO:0070662 mast cell proliferation(GO:0070662)
4.1 8.2 GO:0071464 cellular response to hydrostatic pressure(GO:0071464)
4.1 4.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
4.1 4.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
4.1 16.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
4.0 24.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
4.0 60.4 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
4.0 15.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
3.9 15.7 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
3.9 11.8 GO:0006982 response to lipid hydroperoxide(GO:0006982)
3.9 3.9 GO:0006498 N-terminal protein lipidation(GO:0006498)
3.8 11.5 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
3.8 23.0 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
3.8 15.2 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
3.8 15.2 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
3.8 7.6 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
3.8 3.8 GO:0032058 positive regulation of translation in response to stress(GO:0032056) positive regulation of translational initiation in response to stress(GO:0032058)
3.8 3.8 GO:0036245 cellular response to menadione(GO:0036245)
3.7 22.4 GO:0038016 insulin receptor internalization(GO:0038016)
3.7 14.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
3.7 11.1 GO:0030573 bile acid catabolic process(GO:0030573)
3.7 22.0 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
3.6 10.9 GO:0006683 galactosylceramide catabolic process(GO:0006683)
3.6 47.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
3.6 79.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
3.6 10.7 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
3.5 14.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
3.5 3.5 GO:0032423 regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
3.5 21.1 GO:0019732 antifungal humoral response(GO:0019732)
3.5 20.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
3.5 13.8 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
3.4 10.3 GO:0071529 cementum mineralization(GO:0071529)
3.4 34.4 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
3.4 17.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
3.3 6.7 GO:0002314 germinal center B cell differentiation(GO:0002314)
3.3 10.0 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
3.3 10.0 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
3.3 13.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
3.3 9.9 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
3.3 6.6 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
3.3 9.9 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
3.3 13.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
3.3 3.3 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
3.3 32.8 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
3.3 3.3 GO:2000410 regulation of thymocyte migration(GO:2000410)
3.3 9.8 GO:0010046 response to mycotoxin(GO:0010046)
3.3 6.5 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
3.2 19.5 GO:0015680 intracellular copper ion transport(GO:0015680)
3.2 376.7 GO:0031295 T cell costimulation(GO:0031295)
3.2 25.3 GO:0015705 iodide transport(GO:0015705)
3.2 31.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
3.2 25.2 GO:0001887 selenium compound metabolic process(GO:0001887)
3.1 6.3 GO:0071421 manganese ion transmembrane transport(GO:0071421)
3.1 9.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
3.1 6.2 GO:1903236 regulation of leukocyte tethering or rolling(GO:1903236)
3.1 12.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
3.1 3.1 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
3.1 24.7 GO:0070995 NADPH oxidation(GO:0070995)
3.1 3.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
3.1 9.2 GO:0034769 basement membrane disassembly(GO:0034769)
3.0 3.0 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
3.0 3.0 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
3.0 9.0 GO:0009720 detection of hormone stimulus(GO:0009720) detection of endogenous stimulus(GO:0009726)
3.0 9.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
3.0 18.0 GO:1903936 cellular response to sodium arsenite(GO:1903936)
3.0 8.9 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
3.0 3.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
3.0 53.4 GO:0015671 oxygen transport(GO:0015671)
2.9 5.9 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
2.9 29.1 GO:0006116 NADH oxidation(GO:0006116)
2.9 14.4 GO:0032494 response to peptidoglycan(GO:0032494)
2.9 20.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
2.9 2.9 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
2.9 20.0 GO:0015811 L-cystine transport(GO:0015811)
2.8 14.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
2.8 8.5 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
2.8 2.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
2.8 5.6 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
2.8 16.6 GO:0043366 beta selection(GO:0043366)
2.8 19.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
2.8 2.8 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
2.7 2.7 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
2.7 8.2 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
2.7 10.9 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
2.7 19.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
2.7 8.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.7 8.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
2.7 10.7 GO:0035900 response to isolation stress(GO:0035900)
2.7 8.0 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
2.6 13.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
2.6 5.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
2.6 76.3 GO:0045730 respiratory burst(GO:0045730)
2.6 13.1 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
2.6 18.2 GO:0045007 depurination(GO:0045007)
2.6 20.8 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
2.6 7.8 GO:0060366 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
2.6 2.6 GO:0007060 male meiosis chromosome segregation(GO:0007060)
2.6 5.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
2.6 7.7 GO:1901097 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of autophagosome maturation(GO:1901097)
2.5 17.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
2.5 7.5 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) positive regulation of fibril organization(GO:1902905)
2.5 12.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
2.5 5.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
2.5 138.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
2.5 12.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
2.4 4.9 GO:0071104 response to interleukin-9(GO:0071104)
2.4 9.5 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
2.4 33.2 GO:2001204 regulation of osteoclast development(GO:2001204)
2.4 21.3 GO:0045217 cell-cell junction maintenance(GO:0045217)
2.4 7.1 GO:0002384 hepatic immune response(GO:0002384)
2.4 4.7 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
2.3 16.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
2.3 7.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
2.3 32.8 GO:0043117 positive regulation of vascular permeability(GO:0043117)
2.3 11.7 GO:1901563 response to camptothecin(GO:1901563)
2.3 14.0 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
2.3 2.3 GO:0007183 SMAD protein complex assembly(GO:0007183)
2.3 4.7 GO:0061582 intestinal epithelial cell migration(GO:0061582)
2.3 4.7 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.3 9.3 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
2.3 9.3 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
2.3 2.3 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
2.3 9.3 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
2.3 4.6 GO:0070842 aggresome assembly(GO:0070842)
2.3 27.7 GO:0048251 elastic fiber assembly(GO:0048251)
2.3 2.3 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
2.3 13.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
2.3 4.6 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
2.3 6.9 GO:0018094 protein polyglycylation(GO:0018094)
2.3 4.6 GO:0060374 mast cell differentiation(GO:0060374)
2.3 6.9 GO:0036090 cleavage furrow ingression(GO:0036090)
2.3 20.6 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
2.3 11.3 GO:0045023 G0 to G1 transition(GO:0045023)
2.3 4.5 GO:0036269 swimming behavior(GO:0036269)
2.2 15.7 GO:0034587 piRNA metabolic process(GO:0034587)
2.2 6.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
2.2 9.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
2.2 49.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
2.2 6.7 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
2.2 8.9 GO:0071918 urea transmembrane transport(GO:0071918)
2.2 13.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
2.2 4.4 GO:0015840 urea transport(GO:0015840)
2.2 10.9 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
2.2 2.2 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
2.2 47.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
2.2 19.6 GO:0002227 innate immune response in mucosa(GO:0002227)
2.2 6.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
2.2 15.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
2.2 6.5 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
2.1 17.1 GO:0006013 mannose metabolic process(GO:0006013)
2.1 6.4 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
2.1 21.3 GO:0018377 protein myristoylation(GO:0018377)
2.1 4.2 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
2.1 14.8 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
2.1 10.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
2.1 2.1 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
2.1 14.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
2.0 8.1 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
2.0 6.1 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
2.0 26.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
2.0 4.0 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
2.0 2.0 GO:0072209 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
2.0 9.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
2.0 19.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
2.0 5.9 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
1.9 5.8 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.9 13.5 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
1.9 5.7 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.9 3.8 GO:1903413 cellular response to bile acid(GO:1903413)
1.9 32.5 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
1.9 34.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
1.9 1.9 GO:1902410 mitotic cytokinetic process(GO:1902410)
1.9 20.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.9 5.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
1.9 31.6 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
1.8 5.5 GO:0043379 memory T cell differentiation(GO:0043379)
1.8 9.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
1.8 5.5 GO:0071504 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
1.8 29.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
1.8 5.5 GO:0042631 cellular response to water deprivation(GO:0042631)
1.8 3.6 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
1.8 112.5 GO:0006968 cellular defense response(GO:0006968)
1.8 1.8 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
1.8 7.2 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.8 7.2 GO:0009822 alkaloid catabolic process(GO:0009822)
1.8 257.4 GO:0002377 immunoglobulin production(GO:0002377)
1.8 5.4 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.8 7.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
1.8 1.8 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
1.8 1.8 GO:0046110 purine nucleobase catabolic process(GO:0006145) xanthine metabolic process(GO:0046110)
1.8 3.5 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
1.8 8.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.8 8.8 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
1.8 7.0 GO:0043335 protein unfolding(GO:0043335)
1.7 7.0 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
1.7 5.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
1.7 5.2 GO:0070269 pyroptosis(GO:0070269)
1.7 3.4 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
1.7 20.6 GO:0006824 cobalt ion transport(GO:0006824)
1.7 6.9 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
1.7 6.9 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
1.7 12.0 GO:0018095 protein polyglutamylation(GO:0018095)
1.7 20.5 GO:0042738 exogenous drug catabolic process(GO:0042738)
1.7 15.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
1.7 13.6 GO:0072719 cellular response to cisplatin(GO:0072719)
1.7 1.7 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
1.7 11.9 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
1.7 6.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.6 6.6 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
1.6 14.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
1.6 8.2 GO:0044245 polysaccharide digestion(GO:0044245)
1.6 22.9 GO:0032495 response to muramyl dipeptide(GO:0032495)
1.6 1.6 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
1.6 3.3 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
1.6 9.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.6 3.3 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
1.6 3.2 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
1.6 6.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.6 8.0 GO:1900121 negative regulation of receptor binding(GO:1900121)
1.6 8.0 GO:0072708 response to sorbitol(GO:0072708)
1.6 38.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
1.6 11.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
1.6 6.4 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
1.6 8.0 GO:0030259 lipid glycosylation(GO:0030259)
1.6 14.3 GO:0001661 conditioned taste aversion(GO:0001661)
1.6 4.7 GO:0016256 N-glycan processing to lysosome(GO:0016256)
1.6 22.1 GO:1990845 adaptive thermogenesis(GO:1990845)
1.6 6.3 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.6 10.9 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
1.6 4.7 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
1.6 3.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
1.6 9.4 GO:0007000 nucleolus organization(GO:0007000)
1.6 1.6 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
1.6 7.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.5 3.1 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
1.5 1.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
1.5 6.2 GO:1905229 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
1.5 3.1 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.5 9.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.5 6.1 GO:0030910 optic placode formation(GO:0001743) olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.5 12.2 GO:0001554 luteolysis(GO:0001554)
1.5 7.6 GO:0030242 pexophagy(GO:0030242)
1.5 4.6 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
1.5 6.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
1.5 3.0 GO:0002215 defense response to nematode(GO:0002215)
1.5 1.5 GO:0042137 sequestering of neurotransmitter(GO:0042137)
1.5 3.0 GO:0061056 sclerotome development(GO:0061056)
1.5 4.4 GO:0033700 phospholipid efflux(GO:0033700)
1.5 4.4 GO:1905063 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) regulation of vascular smooth muscle cell differentiation(GO:1905063) negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
1.5 4.4 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
1.5 11.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
1.5 4.4 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
1.5 4.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.5 14.6 GO:0007320 insemination(GO:0007320)
1.4 8.7 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
1.4 10.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.4 4.3 GO:0046968 peptide antigen transport(GO:0046968)
1.4 8.6 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
1.4 1.4 GO:0035634 response to stilbenoid(GO:0035634)
1.4 7.1 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
1.4 11.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
1.4 7.1 GO:2000870 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
1.4 5.6 GO:0032306 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
1.4 2.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
1.4 9.8 GO:0061370 testosterone biosynthetic process(GO:0061370)
1.4 2.8 GO:0051464 positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
1.4 22.3 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
1.4 9.7 GO:0045910 negative regulation of DNA recombination(GO:0045910)
1.4 5.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.4 19.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.4 4.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.4 13.9 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.4 6.9 GO:0006041 glucosamine metabolic process(GO:0006041)
1.4 4.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.4 55.0 GO:0018149 peptide cross-linking(GO:0018149)
1.4 6.9 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.4 2.7 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.3 2.7 GO:0042133 neurotransmitter metabolic process(GO:0042133)
1.3 18.9 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
1.3 5.4 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
1.3 5.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
1.3 1.3 GO:0007521 muscle cell fate determination(GO:0007521)
1.3 5.3 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
1.3 2.7 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
1.3 13.3 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.3 6.6 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
1.3 7.9 GO:0072672 neutrophil extravasation(GO:0072672)
1.3 4.0 GO:1904640 response to methionine(GO:1904640)
1.3 2.6 GO:0021558 trochlear nerve development(GO:0021558)
1.3 69.9 GO:0006953 acute-phase response(GO:0006953)
1.3 2.6 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
1.3 2.6 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
1.3 6.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
1.3 3.9 GO:0030327 prenylated protein catabolic process(GO:0030327)
1.3 20.8 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
1.3 13.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
1.3 9.1 GO:0071265 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
1.3 9.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.3 3.9 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.3 6.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.3 2.6 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
1.3 6.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.3 5.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
1.3 2.6 GO:1901079 positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899)
1.3 6.4 GO:0048102 autophagic cell death(GO:0048102)
1.3 5.1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
1.3 1.3 GO:0035963 cellular response to interleukin-13(GO:0035963)
1.3 7.6 GO:0060481 lobar bronchus epithelium development(GO:0060481)
1.3 3.8 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.3 3.8 GO:0018343 protein farnesylation(GO:0018343)
1.3 3.8 GO:2000252 negative regulation of feeding behavior(GO:2000252)
1.3 7.5 GO:0033088 immature T cell proliferation in thymus(GO:0033080) regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.3 5.0 GO:0006477 protein sulfation(GO:0006477)
1.2 2.5 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
1.2 2.5 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
1.2 4.9 GO:0009305 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
1.2 7.4 GO:0035617 stress granule disassembly(GO:0035617)
1.2 4.9 GO:0015942 formate metabolic process(GO:0015942)
1.2 20.9 GO:0097186 amelogenesis(GO:0097186)
1.2 3.7 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
1.2 8.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.2 4.9 GO:0050957 equilibrioception(GO:0050957)
1.2 16.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
1.2 30.2 GO:0006706 steroid catabolic process(GO:0006706)
1.2 2.4 GO:0009438 methylglyoxal metabolic process(GO:0009438)
1.2 2.4 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
1.2 10.7 GO:0098535 de novo centriole assembly(GO:0098535)
1.2 15.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.2 16.5 GO:2000291 regulation of myoblast proliferation(GO:2000291)
1.2 4.7 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
1.2 3.5 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
1.2 10.6 GO:0060075 regulation of resting membrane potential(GO:0060075)
1.2 9.4 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
1.2 65.6 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
1.2 12.9 GO:0086103 G-protein coupled receptor signaling pathway involved in heart process(GO:0086103)
1.2 5.8 GO:0002286 T cell activation involved in immune response(GO:0002286)
1.2 8.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
1.2 3.5 GO:0045554 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
1.2 54.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
1.2 3.5 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
1.1 14.9 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
1.1 4.6 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
1.1 8.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.1 2.3 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.1 3.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
1.1 3.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.1 6.8 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
1.1 5.6 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.1 1.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
1.1 2.3 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
1.1 18.0 GO:0019835 cytolysis(GO:0019835)
1.1 19.1 GO:0007398 ectoderm development(GO:0007398)
1.1 4.5 GO:0090230 regulation of centromere complex assembly(GO:0090230)
1.1 4.5 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
1.1 1.1 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
1.1 12.3 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
1.1 2.2 GO:0015819 lysine transport(GO:0015819) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transport(GO:1902022) L-lysine import into cell(GO:1903410)
1.1 3.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
1.1 4.4 GO:0033602 gamma-aminobutyric acid catabolic process(GO:0009450) negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of dopamine secretion(GO:0033602) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
1.1 2.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
1.1 10.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
1.1 3.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
1.1 4.4 GO:1990502 dense core granule maturation(GO:1990502)
1.1 2.2 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
1.1 5.5 GO:0035995 detection of muscle stretch(GO:0035995)
1.1 9.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
1.1 3.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
1.1 3.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431)
1.1 1.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
1.1 1.1 GO:0019376 galactolipid catabolic process(GO:0019376)
1.1 7.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
1.1 3.3 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
1.1 1.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
1.1 3.2 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
1.1 3.2 GO:0051918 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of fibrinolysis(GO:0051918)
1.1 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
1.1 5.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
1.1 2.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.1 10.7 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
1.1 2.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
1.1 29.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.1 4.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
1.1 2.1 GO:1990637 response to prolactin(GO:1990637)
1.1 4.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
1.0 27.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
1.0 4.2 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.0 2.1 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
1.0 31.2 GO:0097503 sialylation(GO:0097503)
1.0 2.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
1.0 6.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.0 4.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.0 4.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
1.0 6.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.0 9.2 GO:0051567 histone H3-K9 methylation(GO:0051567)
1.0 6.1 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
1.0 2.0 GO:0051599 response to hydrostatic pressure(GO:0051599)
1.0 4.1 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
1.0 4.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.0 5.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
1.0 5.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.0 9.1 GO:0045054 constitutive secretory pathway(GO:0045054)
1.0 1.0 GO:0042737 drug catabolic process(GO:0042737)
1.0 6.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
1.0 10.1 GO:0015074 DNA integration(GO:0015074)
1.0 3.0 GO:0051941 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) regulation of calcium:sodium antiporter activity(GO:1903279)
1.0 6.0 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
1.0 1.0 GO:0032971 regulation of muscle filament sliding(GO:0032971)
1.0 9.0 GO:0006069 ethanol oxidation(GO:0006069)
1.0 3.0 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
1.0 3.9 GO:0046618 drug export(GO:0046618)
1.0 17.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
1.0 1.0 GO:0023035 CD40 signaling pathway(GO:0023035)
1.0 3.9 GO:0048266 behavioral response to pain(GO:0048266)
1.0 19.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
1.0 4.8 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.0 7.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
1.0 1.9 GO:0090135 actin filament branching(GO:0090135)
1.0 16.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
1.0 3.8 GO:0007512 adult heart development(GO:0007512)
1.0 1.0 GO:0000023 maltose metabolic process(GO:0000023)
1.0 17.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
1.0 5.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.0 6.7 GO:0060452 positive regulation of cardiac muscle contraction(GO:0060452)
1.0 7.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.9 2.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.9 4.7 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.9 2.8 GO:0036233 glycine import(GO:0036233)
0.9 4.7 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.9 30.0 GO:0016601 Rac protein signal transduction(GO:0016601)
0.9 1.9 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.9 2.8 GO:0002933 lipid hydroxylation(GO:0002933)
0.9 7.4 GO:0060973 cell migration involved in heart development(GO:0060973)
0.9 7.4 GO:0007506 gonadal mesoderm development(GO:0007506)
0.9 7.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.9 4.6 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.9 40.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.9 5.5 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.9 4.6 GO:0035624 receptor transactivation(GO:0035624)
0.9 2.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.9 7.3 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.9 7.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.9 2.7 GO:0021571 rhombomere 5 development(GO:0021571) rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.9 3.6 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.9 5.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.9 1.8 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.9 14.3 GO:0055026 negative regulation of cardiac muscle tissue development(GO:0055026)
0.9 2.7 GO:0061107 seminal vesicle development(GO:0061107)
0.9 4.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.9 4.4 GO:2000169 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.9 6.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483)
0.9 4.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.9 9.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.9 4.4 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.9 2.6 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.9 2.6 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.9 47.9 GO:0015701 bicarbonate transport(GO:0015701)
0.9 5.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.9 28.6 GO:0032570 response to progesterone(GO:0032570)
0.9 1.7 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.9 13.7 GO:0042116 macrophage activation(GO:0042116)
0.9 13.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.9 6.9 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.9 1.7 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.8 3.4 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.8 3.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.8 1.7 GO:1902218 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.8 4.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.8 144.1 GO:0002250 adaptive immune response(GO:0002250)
0.8 11.6 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.8 9.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.8 1.7 GO:0001757 somite specification(GO:0001757)
0.8 1.7 GO:0003064 regulation of heart rate by hormone(GO:0003064)
0.8 14.8 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.8 4.9 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.8 19.7 GO:0009994 oocyte differentiation(GO:0009994)
0.8 2.5 GO:1902988 neurofibrillary tangle assembly(GO:1902988)
0.8 7.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.8 1.6 GO:0001575 globoside metabolic process(GO:0001575)
0.8 4.9 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.8 0.8 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.8 1.6 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.8 21.9 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.8 5.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.8 7.3 GO:0001675 acrosome assembly(GO:0001675)
0.8 8.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.8 7.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.8 3.2 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.8 4.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.8 7.2 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.8 8.0 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.8 11.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.8 10.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.8 2.4 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.8 8.7 GO:0014029 neural crest formation(GO:0014029)
0.8 3.2 GO:0010157 response to chlorate(GO:0010157)
0.8 4.7 GO:0021633 optic nerve structural organization(GO:0021633)
0.8 2.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.8 2.4 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.8 19.5 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.8 3.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.8 38.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.8 3.9 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.8 11.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.8 0.8 GO:0042938 dipeptide transport(GO:0042938)
0.8 3.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.8 16.8 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.8 26.7 GO:0010107 potassium ion import(GO:0010107)
0.8 6.9 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.8 2.3 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.8 16.6 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.8 18.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.8 9.8 GO:0035641 locomotory exploration behavior(GO:0035641)
0.8 4.5 GO:0015816 glycine transport(GO:0015816)
0.8 6.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.8 3.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.8 7.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.8 2.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.7 10.5 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.7 14.2 GO:0006853 carnitine shuttle(GO:0006853)
0.7 33.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.7 9.0 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.7 4.5 GO:0060081 membrane hyperpolarization(GO:0060081)
0.7 8.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.7 1.5 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.7 1.5 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.7 2.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.7 2.9 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.7 14.5 GO:0035456 response to interferon-beta(GO:0035456)
0.7 2.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.7 2.2 GO:1903347 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.7 5.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.7 2.2 GO:0035483 negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.7 12.2 GO:0009299 mRNA transcription(GO:0009299)
0.7 3.6 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.7 3.6 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.7 7.8 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.7 43.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.7 5.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.7 3.5 GO:0001714 endodermal cell fate specification(GO:0001714)
0.7 16.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.7 4.9 GO:0060215 primitive hemopoiesis(GO:0060215)
0.7 2.8 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.7 3.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.7 1.4 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.7 5.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.7 2.7 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.7 2.0 GO:0032364 oxygen homeostasis(GO:0032364)
0.7 9.5 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.7 1.4 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.7 4.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.7 6.7 GO:0051014 actin filament severing(GO:0051014)
0.7 4.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.7 4.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.7 1.3 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.7 1.3 GO:0002507 tolerance induction(GO:0002507)
0.7 1.3 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.7 12.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.7 6.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.7 6.0 GO:0060033 anatomical structure regression(GO:0060033)
0.7 3.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.7 19.8 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.7 4.6 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.7 1.3 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.7 10.5 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.7 1.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.7 2.6 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.7 11.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.6 5.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.6 3.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.6 1.9 GO:0042412 taurine biosynthetic process(GO:0042412)
0.6 1.9 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.6 5.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.6 1.9 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.6 3.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.6 5.7 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.6 1.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.6 9.5 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.6 3.1 GO:0033058 directional locomotion(GO:0033058)
0.6 4.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.6 3.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049) cardiolipin acyl-chain remodeling(GO:0035965)
0.6 8.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.6 2.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6 3.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.6 4.3 GO:0007143 female meiotic division(GO:0007143)
0.6 10.4 GO:0005513 detection of calcium ion(GO:0005513)
0.6 1.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.6 4.2 GO:0006568 tryptophan metabolic process(GO:0006568)
0.6 4.2 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.6 4.2 GO:1903003 regulation of protein deubiquitination(GO:0090085) positive regulation of protein deubiquitination(GO:1903003)
0.6 3.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.6 4.2 GO:0080009 mRNA methylation(GO:0080009)
0.6 5.4 GO:0031053 primary miRNA processing(GO:0031053)
0.6 44.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.6 4.1 GO:0090527 actin filament reorganization(GO:0090527)
0.6 18.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.6 2.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.6 4.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.6 2.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of metalloendopeptidase activity(GO:1904683)
0.6 4.6 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.6 6.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.6 8.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.6 2.3 GO:0060039 pericardium development(GO:0060039)
0.6 5.7 GO:0010225 response to UV-C(GO:0010225)
0.6 10.2 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.6 1.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.6 1.7 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.6 1.7 GO:0051541 elastin metabolic process(GO:0051541)
0.6 2.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.6 1.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.6 2.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.6 8.4 GO:0060736 prostate gland growth(GO:0060736)
0.6 2.2 GO:0060017 parathyroid gland development(GO:0060017)
0.6 6.1 GO:0030238 male sex determination(GO:0030238)
0.6 2.8 GO:0036337 Fas signaling pathway(GO:0036337)
0.6 2.8 GO:1904526 regulation of microtubule binding(GO:1904526)
0.6 1.7 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.6 0.6 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533) negative regulation of oligodendrocyte differentiation(GO:0048715)
0.5 2.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.5 8.1 GO:0045821 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.5 3.8 GO:0061709 reticulophagy(GO:0061709)
0.5 6.5 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.5 5.4 GO:0039536 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) negative regulation of RIG-I signaling pathway(GO:0039536)
0.5 3.8 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.5 1.1 GO:0019323 pentose catabolic process(GO:0019323)
0.5 1.1 GO:0035564 regulation of kidney size(GO:0035564) regulation of pronephros size(GO:0035565)
0.5 1.6 GO:2000706 dense core granule biogenesis(GO:0061110) amniotic stem cell differentiation(GO:0097086) regulation of dense core granule biogenesis(GO:2000705) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.5 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.5 2.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5 33.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.5 5.2 GO:1900451 positive regulation of glutamate receptor signaling pathway(GO:1900451)
0.5 10.4 GO:0050909 sensory perception of taste(GO:0050909)
0.5 3.6 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.5 2.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.5 2.0 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.5 10.2 GO:0046710 GDP metabolic process(GO:0046710)
0.5 10.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.5 4.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.5 2.0 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.5 1.0 GO:0051450 myoblast proliferation(GO:0051450)
0.5 6.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.5 2.0 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.5 1.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.5 16.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.5 2.0 GO:0030916 otic vesicle formation(GO:0030916)
0.5 2.4 GO:0072553 terminal button organization(GO:0072553)
0.5 12.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.5 1.5 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.5 6.8 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.5 1.9 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.5 1.9 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.5 6.6 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.5 5.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.5 3.8 GO:0010002 cardioblast differentiation(GO:0010002)
0.5 2.8 GO:0006543 glutamine catabolic process(GO:0006543)
0.5 0.9 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.5 5.2 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.5 2.8 GO:0035063 nuclear speck organization(GO:0035063)
0.5 3.2 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.5 3.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.5 1.4 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.4 0.9 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.4 1.8 GO:0045760 positive regulation of action potential(GO:0045760)
0.4 6.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.4 2.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.4 2.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.4 1.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.4 2.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.4 4.4 GO:0051923 sulfation(GO:0051923)
0.4 2.2 GO:0030903 notochord development(GO:0030903)
0.4 10.5 GO:0030488 tRNA methylation(GO:0030488)
0.4 1.3 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.4 1.3 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.4 5.1 GO:0032094 response to food(GO:0032094)
0.4 0.8 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.4 1.7 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.4 5.1 GO:0019731 antibacterial humoral response(GO:0019731)
0.4 3.0 GO:0018342 protein prenylation(GO:0018342) protein geranylgeranylation(GO:0018344) prenylation(GO:0097354)
0.4 2.1 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.4 12.8 GO:0031641 regulation of myelination(GO:0031641)
0.4 2.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.4 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.4 0.8 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.4 0.8 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.4 1.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.4 2.4 GO:0022605 ovarian cumulus expansion(GO:0001550) oogenesis stage(GO:0022605) fused antrum stage(GO:0048165)
0.4 1.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.4 1.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.4 5.2 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.4 2.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.4 5.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 4.3 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.4 3.9 GO:0035095 behavioral response to nicotine(GO:0035095)
0.4 1.2 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.4 2.7 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.4 2.7 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.4 126.0 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.4 2.3 GO:0008218 bioluminescence(GO:0008218)
0.4 2.3 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.4 3.8 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 1.1 GO:0006857 oligopeptide transport(GO:0006857)
0.4 7.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.4 1.1 GO:0010744 positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.4 3.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.4 1.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.4 2.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.4 21.2 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.4 9.3 GO:0030279 negative regulation of ossification(GO:0030279)
0.4 7.1 GO:0043171 peptide catabolic process(GO:0043171)
0.4 4.2 GO:0003338 metanephros morphogenesis(GO:0003338)
0.4 1.8 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.3 3.5 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.3 1.4 GO:0015813 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.3 2.1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.3 11.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 8.3 GO:0015698 inorganic anion transport(GO:0015698)
0.3 3.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.3 33.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3 3.0 GO:0032790 ribosome disassembly(GO:0032790)
0.3 4.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 2.7 GO:0015693 magnesium ion transport(GO:0015693)
0.3 11.2 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.3 4.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 3.5 GO:0048665 neuron fate specification(GO:0048665)
0.3 2.6 GO:0045124 regulation of bone resorption(GO:0045124)
0.3 1.0 GO:0090131 mesenchyme migration(GO:0090131)
0.3 1.9 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3 3.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 1.2 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.3 1.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.3 4.0 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.3 3.0 GO:0019730 antimicrobial humoral response(GO:0019730)
0.3 3.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.3 3.0 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.3 0.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.3 5.7 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.3 2.1 GO:0044065 regulation of respiratory system process(GO:0044065)
0.3 5.1 GO:0007140 male meiosis(GO:0007140)
0.3 4.1 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.3 1.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.3 2.2 GO:0002021 response to dietary excess(GO:0002021)
0.3 1.7 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.3 3.3 GO:0034389 lipid particle organization(GO:0034389)
0.3 3.6 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.3 0.5 GO:0001659 temperature homeostasis(GO:0001659)
0.3 3.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 3.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 0.8 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.3 0.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.3 13.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 6.4 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.3 1.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.3 7.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 13.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 2.0 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.2 1.0 GO:0006004 fucose metabolic process(GO:0006004)
0.2 0.7 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.2 0.7 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2 0.9 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 1.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 1.2 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.2 4.8 GO:0046849 bone remodeling(GO:0046849)
0.2 1.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.7 GO:0098911 regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.2 0.9 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959) regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2 7.3 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.2 0.9 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 4.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 6.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.2 3.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.2 1.1 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.2 0.8 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2 1.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 1.2 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.2 0.4 GO:1901018 positive regulation of potassium ion transmembrane transporter activity(GO:1901018)
0.2 3.4 GO:0097264 self proteolysis(GO:0097264)
0.2 1.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 2.3 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.2 1.1 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.2 1.3 GO:0072319 synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319)
0.2 0.4 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.2 3.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.2 1.4 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.2 0.7 GO:2000194 regulation of female gonad development(GO:2000194)
0.2 0.2 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.2 1.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 1.9 GO:0042417 dopamine metabolic process(GO:0042417)
0.2 18.5 GO:0007265 Ras protein signal transduction(GO:0007265)
0.2 0.3 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2 2.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 0.5 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 1.2 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.9 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 2.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.7 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 1.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.4 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 2.3 GO:0048753 pigment granule organization(GO:0048753)
0.1 0.9 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.4 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 0.4 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.3 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 0.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.5 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.1 2.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.9 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.5 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.1 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.1 0.1 GO:1902474 regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
0.1 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 4.8 GO:0070268 cornification(GO:0070268)
0.1 0.2 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.2 GO:0030043 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) actin filament fragmentation(GO:0030043) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.5 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 1.0 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0001947 heart looping(GO:0001947) embryonic heart tube morphogenesis(GO:0003143)
0.0 0.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.0 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.0 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
27.7 27.7 GO:0071753 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
24.8 149.0 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
20.6 82.4 GO:0071748 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
19.0 913.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
17.9 340.2 GO:0042613 MHC class II protein complex(GO:0042613)
12.0 132.3 GO:0042612 MHC class I protein complex(GO:0042612)
8.8 26.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
8.5 33.9 GO:0005602 complement component C1 complex(GO:0005602)
7.4 52.0 GO:0032010 phagolysosome(GO:0032010)
7.4 7.4 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
7.1 35.5 GO:0019815 B cell receptor complex(GO:0019815)
7.1 42.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
6.8 74.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
5.9 29.5 GO:0036398 TCR signalosome(GO:0036398)
5.9 64.8 GO:0060171 stereocilium membrane(GO:0060171)
5.1 15.3 GO:0070701 mucus layer(GO:0070701)
5.0 15.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
5.0 29.8 GO:1990584 cardiac Troponin complex(GO:1990584)
5.0 24.9 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
4.9 24.7 GO:1990031 pinceau fiber(GO:1990031)
4.9 29.2 GO:0044194 cytolytic granule(GO:0044194)
4.7 18.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
4.5 63.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
4.2 71.2 GO:0042101 T cell receptor complex(GO:0042101)
4.2 25.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
4.1 77.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
4.0 15.9 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
4.0 98.9 GO:0001891 phagocytic cup(GO:0001891)
3.9 15.7 GO:0071546 pi-body(GO:0071546)
3.8 15.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
3.5 46.1 GO:0005833 hemoglobin complex(GO:0005833)
3.4 65.4 GO:0005641 nuclear envelope lumen(GO:0005641)
3.3 63.6 GO:0042629 mast cell granule(GO:0042629)
3.2 15.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
3.2 19.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
3.1 15.7 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
3.1 12.5 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
3.1 21.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
2.9 5.8 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
2.8 33.8 GO:0097486 multivesicular body lumen(GO:0097486)
2.8 2.8 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
2.7 10.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
2.7 37.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
2.7 8.0 GO:0070195 growth hormone receptor complex(GO:0070195)
2.6 23.8 GO:0071953 elastic fiber(GO:0071953)
2.6 10.5 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
2.6 142.2 GO:0001772 immunological synapse(GO:0001772)
2.6 12.9 GO:0001652 granular component(GO:0001652)
2.4 12.2 GO:1990761 growth cone lamellipodium(GO:1990761)
2.4 19.5 GO:0035976 AP1 complex(GO:0035976)
2.4 17.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
2.4 4.8 GO:0061689 tricellular tight junction(GO:0061689)
2.3 53.5 GO:0042627 chylomicron(GO:0042627)
2.3 16.2 GO:0033391 chromatoid body(GO:0033391)
2.2 4.4 GO:0030991 intraciliary transport particle A(GO:0030991)
2.2 8.7 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
2.1 12.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
2.1 313.2 GO:0072562 blood microparticle(GO:0072562)
2.1 6.2 GO:0000805 X chromosome(GO:0000805)
2.1 33.0 GO:0031089 platelet dense granule lumen(GO:0031089)
2.0 14.3 GO:1990745 EARP complex(GO:1990745)
2.0 18.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
2.0 2.0 GO:0035061 interchromatin granule(GO:0035061)
2.0 5.9 GO:0031251 PAN complex(GO:0031251)
1.9 13.5 GO:1990111 spermatoproteasome complex(GO:1990111)
1.9 69.2 GO:0008305 integrin complex(GO:0008305)
1.9 17.1 GO:0070652 HAUS complex(GO:0070652)
1.8 11.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.8 10.9 GO:0033553 rDNA heterochromatin(GO:0033553)
1.8 5.4 GO:0033263 CORVET complex(GO:0033263)
1.8 7.1 GO:0070876 SOSS complex(GO:0070876)
1.8 5.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
1.7 10.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.7 8.6 GO:0005577 fibrinogen complex(GO:0005577)
1.7 57.9 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
1.7 5.0 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
1.6 6.6 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
1.6 159.4 GO:0070821 tertiary granule membrane(GO:0070821)
1.6 6.5 GO:1990879 CST complex(GO:1990879)
1.6 19.2 GO:0097512 cardiac myofibril(GO:0097512)
1.6 9.4 GO:1990769 proximal neuron projection(GO:1990769)
1.5 4.6 GO:0030312 external encapsulating structure(GO:0030312)
1.5 187.8 GO:0035578 azurophil granule lumen(GO:0035578)
1.5 3.0 GO:0032797 SMN complex(GO:0032797)
1.5 13.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.5 37.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.5 7.3 GO:0034464 BBSome(GO:0034464)
1.4 10.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
1.4 7.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.4 14.1 GO:0035253 ciliary rootlet(GO:0035253)
1.4 7.0 GO:0032302 MutSbeta complex(GO:0032302)
1.4 24.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.4 11.0 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
1.4 20.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.4 5.5 GO:0000801 central element(GO:0000801)
1.4 13.5 GO:0046581 intercellular canaliculus(GO:0046581)
1.3 10.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.3 9.2 GO:0072687 meiotic spindle(GO:0072687)
1.3 11.5 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
1.3 44.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.3 7.6 GO:0070545 PeBoW complex(GO:0070545)
1.3 2.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.3 7.5 GO:0032584 growth cone membrane(GO:0032584)
1.3 6.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
1.2 6.2 GO:0089701 U2AF(GO:0089701)
1.2 3.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.2 56.8 GO:0001533 cornified envelope(GO:0001533)
1.2 4.9 GO:0097443 sorting endosome(GO:0097443)
1.2 9.8 GO:0043203 axon hillock(GO:0043203)
1.2 15.6 GO:0097413 Lewy body(GO:0097413)
1.2 3.6 GO:0032590 dendrite membrane(GO:0032590)
1.2 4.7 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
1.2 11.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.2 5.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.2 22.2 GO:0030014 CCR4-NOT complex(GO:0030014)
1.2 41.7 GO:0034451 centriolar satellite(GO:0034451)
1.2 5.8 GO:0045179 apical cortex(GO:0045179)
1.1 17.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.1 4.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.1 4.5 GO:0031905 early endosome lumen(GO:0031905)
1.1 3.3 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
1.1 4.4 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
1.1 2.2 GO:0097209 epidermal lamellar body(GO:0097209)
1.1 6.5 GO:0044327 dendritic spine head(GO:0044327)
1.1 48.2 GO:0016235 aggresome(GO:0016235)
1.1 17.0 GO:0031904 endosome lumen(GO:0031904)
1.0 119.9 GO:0005796 Golgi lumen(GO:0005796)
1.0 3.1 GO:0034657 GID complex(GO:0034657)
1.0 1.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.0 4.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
1.0 5.0 GO:0032444 activin responsive factor complex(GO:0032444)
1.0 3.0 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
1.0 3.0 GO:0097165 nuclear stress granule(GO:0097165)
1.0 4.9 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
1.0 8.7 GO:0032059 bleb(GO:0032059)
1.0 70.4 GO:0043202 lysosomal lumen(GO:0043202)
1.0 5.8 GO:0005594 collagen type IX trimer(GO:0005594)
1.0 68.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.9 13.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.9 37.7 GO:0016592 mediator complex(GO:0016592)
0.9 5.6 GO:0002177 manchette(GO:0002177)
0.9 3.7 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.9 4.6 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.9 5.4 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.9 15.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.9 2.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.9 2.6 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.9 4.4 GO:0031310 intrinsic component of vacuolar membrane(GO:0031310)
0.9 2.6 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.9 0.9 GO:0014802 terminal cisterna(GO:0014802)
0.9 2.6 GO:0071821 FANCM-MHF complex(GO:0071821)
0.8 15.1 GO:0036038 MKS complex(GO:0036038)
0.8 25.8 GO:0034706 sodium channel complex(GO:0034706)
0.8 2.5 GO:0097224 sperm connecting piece(GO:0097224)
0.8 2.5 GO:0098536 deuterosome(GO:0098536)
0.8 5.7 GO:0060077 inhibitory synapse(GO:0060077)
0.8 3.2 GO:0036449 microtubule minus-end(GO:0036449)
0.8 20.1 GO:0032982 myosin filament(GO:0032982)
0.8 15.7 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.8 3.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.8 4.6 GO:0097452 GAIT complex(GO:0097452)
0.8 3.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.7 3.0 GO:1990393 3M complex(GO:1990393)
0.7 179.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.7 3.0 GO:0044307 dendritic branch(GO:0044307)
0.7 2.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.7 8.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.7 3.7 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.7 5.1 GO:0000974 Prp19 complex(GO:0000974)
0.7 3.7 GO:0030314 junctional membrane complex(GO:0030314)
0.7 10.8 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.7 2.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.7 5.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.7 2.0 GO:0005745 m-AAA complex(GO:0005745)
0.7 7.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.7 3.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.6 28.6 GO:0035579 specific granule membrane(GO:0035579)
0.6 10.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.6 16.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.6 2.5 GO:0045298 tubulin complex(GO:0045298)
0.6 1.8 GO:0035189 Rb-E2F complex(GO:0035189)
0.6 5.5 GO:0044294 dendritic growth cone(GO:0044294)
0.6 10.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.6 9.7 GO:0031528 microvillus membrane(GO:0031528)
0.6 3.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.6 2.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.6 1.8 GO:0070695 FHF complex(GO:0070695)
0.6 65.8 GO:0031225 anchored component of membrane(GO:0031225)
0.6 8.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.6 2.3 GO:0005879 axonemal microtubule(GO:0005879)
0.6 8.6 GO:0097225 sperm midpiece(GO:0097225)
0.6 3.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.6 2.2 GO:0035363 histone locus body(GO:0035363)
0.6 2.8 GO:0036157 outer dynein arm(GO:0036157)
0.6 39.0 GO:0005581 collagen trimer(GO:0005581)
0.6 2.2 GO:0036128 CatSper complex(GO:0036128)
0.6 2.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.6 31.4 GO:0016459 myosin complex(GO:0016459)
0.5 642.5 GO:0005615 extracellular space(GO:0005615)
0.5 1.6 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.5 3.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.5 3.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.5 1.5 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.5 5.5 GO:0030870 Mre11 complex(GO:0030870)
0.5 4.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.5 11.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 5.2 GO:0097427 microtubule bundle(GO:0097427)
0.5 49.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.5 11.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5 14.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.5 2.3 GO:0030897 HOPS complex(GO:0030897)
0.5 4.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 2.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 1.8 GO:0005579 membrane attack complex(GO:0005579)
0.4 3.1 GO:0042788 polysomal ribosome(GO:0042788)
0.4 6.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 5.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 1.7 GO:0071564 npBAF complex(GO:0071564)
0.4 74.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.4 15.6 GO:0005902 microvillus(GO:0005902)
0.4 5.0 GO:0016013 syntrophin complex(GO:0016013)
0.4 5.3 GO:0017119 Golgi transport complex(GO:0017119)
0.4 2.9 GO:0032280 symmetric synapse(GO:0032280)
0.4 2.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 8.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 8.3 GO:0005801 cis-Golgi network(GO:0005801)
0.4 2.0 GO:0002080 acrosomal membrane(GO:0002080)
0.4 2.3 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.4 1.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4 3.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.4 1.8 GO:0071565 nBAF complex(GO:0071565)
0.3 1.7 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.3 43.2 GO:0016605 PML body(GO:0016605)
0.3 6.2 GO:0005922 connexon complex(GO:0005922)
0.3 23.5 GO:0005814 centriole(GO:0005814)
0.3 4.0 GO:0030008 TRAPP complex(GO:0030008)
0.3 3.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 3.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.3 23.7 GO:0034707 chloride channel complex(GO:0034707)
0.3 3.9 GO:0009925 basal plasma membrane(GO:0009925)
0.3 5.9 GO:0097546 ciliary base(GO:0097546)
0.3 36.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 1.9 GO:0030891 VCB complex(GO:0030891)
0.3 1.8 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 7.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 3.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 0.7 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 2.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 1.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 0.7 GO:0071438 invadopodium membrane(GO:0071438)
0.2 1.8 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2 5.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 11.0 GO:0036064 ciliary basal body(GO:0036064)
0.2 0.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 0.6 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.2 10.9 GO:0005811 lipid particle(GO:0005811)
0.2 1.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 2.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 1.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 1.8 GO:0005915 zonula adherens(GO:0005915)
0.2 3.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 4.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.2 7.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.2 2.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 8.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 9.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 329.8 GO:0031224 intrinsic component of membrane(GO:0031224)
0.1 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.0 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
24.7 98.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
21.9 153.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
19.2 57.7 GO:0045322 unmethylated CpG binding(GO:0045322)
17.1 51.3 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
17.0 1018.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
16.7 150.2 GO:0043426 MRF binding(GO:0043426)
12.5 50.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
12.1 460.5 GO:0042605 peptide antigen binding(GO:0042605)
11.7 58.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
10.4 83.4 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
10.1 30.3 GO:0008859 exoribonuclease II activity(GO:0008859)
10.0 39.9 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
9.0 36.2 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
8.9 26.8 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
8.5 119.4 GO:0019864 IgG binding(GO:0019864)
8.1 40.4 GO:0042610 CD8 receptor binding(GO:0042610)
8.1 32.3 GO:0004341 gluconolactonase activity(GO:0004341)
7.7 23.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
7.6 22.9 GO:0004878 complement component C5a receptor activity(GO:0004878)
7.6 30.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
7.5 30.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
7.4 7.4 GO:0001851 complement component C3b binding(GO:0001851)
6.3 19.0 GO:0016154 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
6.3 19.0 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
6.2 50.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
6.1 892.8 GO:0003823 antigen binding(GO:0003823)
6.0 54.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
6.0 18.0 GO:0042289 MHC class II protein binding(GO:0042289)
5.9 17.8 GO:0004912 interleukin-3 receptor activity(GO:0004912)
5.9 29.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
5.7 22.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
5.6 33.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
5.3 21.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
5.3 15.9 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
5.2 31.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
5.2 77.7 GO:0005344 oxygen transporter activity(GO:0005344)
5.2 31.0 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
5.1 15.4 GO:0033749 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
5.1 20.5 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
4.9 24.3 GO:0004771 sterol esterase activity(GO:0004771)
4.8 14.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
4.7 28.4 GO:0030172 troponin C binding(GO:0030172)
4.7 14.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
4.7 14.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
4.6 37.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
4.5 22.7 GO:0032395 MHC class II receptor activity(GO:0032395)
4.4 17.7 GO:0004773 steryl-sulfatase activity(GO:0004773)
4.2 12.7 GO:0030350 iron-responsive element binding(GO:0030350)
4.2 21.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
4.2 12.6 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
4.2 20.9 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
4.1 20.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
4.0 63.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
3.8 11.5 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
3.8 22.6 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
3.7 18.6 GO:0004803 transposase activity(GO:0004803)
3.6 10.9 GO:0004336 galactosylceramidase activity(GO:0004336)
3.6 47.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
3.6 21.8 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
3.6 43.0 GO:0008430 selenium binding(GO:0008430)
3.6 28.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
3.5 42.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
3.5 24.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
3.5 3.5 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
3.4 17.2 GO:0043208 glycosphingolipid binding(GO:0043208)
3.4 20.2 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
3.4 30.2 GO:0004875 complement receptor activity(GO:0004875)
3.3 10.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
3.2 9.7 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
3.2 32.4 GO:0008131 primary amine oxidase activity(GO:0008131)
3.2 9.6 GO:0016497 substance K receptor activity(GO:0016497)
3.1 18.7 GO:0004882 androgen receptor activity(GO:0004882)
3.1 12.3 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
3.1 12.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
3.0 6.1 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
3.0 12.1 GO:0031716 calcitonin receptor binding(GO:0031716)
3.0 6.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
2.9 14.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
2.9 11.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.9 40.7 GO:0031419 cobalamin binding(GO:0031419)
2.9 11.5 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
2.8 14.2 GO:0004522 ribonuclease A activity(GO:0004522)
2.8 8.5 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
2.8 39.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.8 103.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
2.7 16.3 GO:0008420 CTD phosphatase activity(GO:0008420)
2.7 8.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
2.7 8.1 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
2.7 8.1 GO:0001601 peptide YY receptor activity(GO:0001601)
2.7 2.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
2.6 7.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
2.6 2.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
2.5 7.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
2.5 10.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
2.5 15.0 GO:0071723 lipopeptide binding(GO:0071723)
2.5 19.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
2.5 14.7 GO:0008172 S-methyltransferase activity(GO:0008172)
2.4 7.3 GO:0016936 galactoside binding(GO:0016936)
2.4 26.6 GO:0051525 NFAT protein binding(GO:0051525)
2.4 7.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
2.4 14.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
2.4 12.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
2.4 14.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
2.4 4.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
2.4 21.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
2.4 16.6 GO:0032393 MHC class I receptor activity(GO:0032393)
2.4 7.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
2.3 9.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
2.3 7.0 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
2.3 9.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
2.3 11.6 GO:0042296 ISG15 transferase activity(GO:0042296)
2.3 6.9 GO:0035473 lipase binding(GO:0035473)
2.3 16.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
2.3 6.9 GO:0048030 disaccharide binding(GO:0048030)
2.3 6.9 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
2.3 6.9 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
2.3 6.9 GO:0070735 protein-glycine ligase activity(GO:0070735)
2.3 22.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
2.3 20.3 GO:0034235 GPI anchor binding(GO:0034235)
2.2 15.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
2.2 6.7 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
2.2 11.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
2.2 8.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
2.2 2.2 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
2.2 6.6 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
2.2 6.6 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
2.2 23.7 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
2.1 21.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
2.1 8.5 GO:0061714 folic acid receptor activity(GO:0061714)
2.1 10.4 GO:0004905 type I interferon receptor activity(GO:0004905)
2.1 18.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.0 79.3 GO:0071889 14-3-3 protein binding(GO:0071889)
2.0 8.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
2.0 14.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
2.0 9.9 GO:0003796 lysozyme activity(GO:0003796)
2.0 5.9 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
2.0 15.8 GO:0098821 BMP receptor activity(GO:0098821)
2.0 7.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.9 5.8 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
1.9 13.6 GO:0019863 IgE binding(GO:0019863)
1.9 5.8 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
1.9 21.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.9 5.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.9 20.8 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
1.9 7.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.9 5.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.8 7.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
1.8 12.9 GO:0001849 complement component C1q binding(GO:0001849)
1.8 7.3 GO:0005148 prolactin receptor binding(GO:0005148)
1.8 5.5 GO:0017129 triglyceride binding(GO:0017129)
1.8 27.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.8 1.8 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
1.8 5.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.8 1.8 GO:0004031 aldehyde oxidase activity(GO:0004031)
1.8 56.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.8 5.3 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
1.8 5.3 GO:0015204 urea transmembrane transporter activity(GO:0015204)
1.8 7.0 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.8 24.6 GO:0042609 CD4 receptor binding(GO:0042609)
1.8 35.1 GO:0042288 MHC class I protein binding(GO:0042288)
1.7 7.0 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
1.7 7.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.7 43.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
1.7 8.6 GO:0030348 syntaxin-3 binding(GO:0030348)
1.7 8.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.7 17.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.7 15.3 GO:0000403 Y-form DNA binding(GO:0000403)
1.7 5.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
1.7 5.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.7 5.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
1.7 15.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.7 10.0 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
1.7 6.7 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
1.7 30.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.7 11.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.7 371.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.6 6.6 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
1.6 1.6 GO:0046978 TAP binding(GO:0046977) TAP1 binding(GO:0046978)
1.6 8.2 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
1.6 9.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.6 6.4 GO:0004992 platelet activating factor receptor activity(GO:0004992)
1.6 3.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.6 12.7 GO:0097642 calcitonin family receptor activity(GO:0097642)
1.6 29.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.6 11.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
1.6 17.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
1.6 14.0 GO:0048019 receptor antagonist activity(GO:0048019)
1.6 6.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.6 4.7 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
1.6 4.7 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
1.5 21.7 GO:0045159 myosin II binding(GO:0045159)
1.5 24.8 GO:0003680 AT DNA binding(GO:0003680)
1.5 7.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.5 4.6 GO:0070573 metallodipeptidase activity(GO:0070573)
1.5 7.6 GO:0050436 microfibril binding(GO:0050436)
1.5 7.6 GO:0001594 trace-amine receptor activity(GO:0001594)
1.5 4.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.5 8.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.5 4.5 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
1.5 14.9 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
1.5 13.2 GO:0004565 beta-galactosidase activity(GO:0004565)
1.5 10.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.4 11.6 GO:0004126 cytidine deaminase activity(GO:0004126)
1.4 10.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.4 8.4 GO:0022821 calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
1.4 19.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
1.4 5.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.4 2.8 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
1.4 4.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.4 8.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
1.4 5.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.4 4.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
1.4 17.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
1.3 9.4 GO:0030911 TPR domain binding(GO:0030911)
1.3 6.7 GO:0003909 DNA ligase activity(GO:0003909)
1.3 25.3 GO:0038191 neuropilin binding(GO:0038191)
1.3 5.3 GO:0045569 TRAIL binding(GO:0045569)
1.3 38.2 GO:0042169 SH2 domain binding(GO:0042169)
1.3 3.9 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
1.3 10.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.3 15.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.3 3.9 GO:0033142 progesterone receptor binding(GO:0033142)
1.3 5.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
1.3 7.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.3 6.4 GO:0016160 amylase activity(GO:0016160)
1.3 5.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.3 5.0 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.3 10.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
1.2 9.9 GO:0004000 adenosine deaminase activity(GO:0004000)
1.2 100.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.2 4.9 GO:0004079 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
1.2 18.5 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
1.2 9.8 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.2 3.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
1.2 3.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.2 10.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
1.2 8.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.2 6.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
1.2 30.6 GO:0071837 HMG box domain binding(GO:0071837)
1.2 2.4 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
1.2 4.7 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
1.2 3.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.2 4.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
1.2 39.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.1 4.6 GO:0002046 opsin binding(GO:0002046)
1.1 2.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.1 5.7 GO:1990254 keratin filament binding(GO:1990254)
1.1 6.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
1.1 3.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.1 59.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.1 7.8 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.1 10.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.1 3.3 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.1 4.4 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
1.1 5.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.1 6.6 GO:0019865 immunoglobulin binding(GO:0019865)
1.1 5.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.1 5.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.1 3.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.1 19.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.1 10.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
1.1 31.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
1.1 1.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.1 3.2 GO:0002113 interleukin-33 binding(GO:0002113)
1.1 25.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.1 8.4 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
1.0 7.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.0 3.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.0 6.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.0 2.1 GO:0004995 tachykinin receptor activity(GO:0004995)
1.0 1.0 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.0 42.3 GO:0030332 cyclin binding(GO:0030332)
1.0 17.1 GO:0042809 vitamin D receptor binding(GO:0042809)
1.0 59.4 GO:0004180 carboxypeptidase activity(GO:0004180)
1.0 10.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
1.0 4.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
1.0 3.0 GO:0008431 vitamin E binding(GO:0008431)
1.0 3.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.0 6.9 GO:0001515 opioid peptide activity(GO:0001515)
1.0 3.9 GO:0015307 drug:proton antiporter activity(GO:0015307)
1.0 3.9 GO:0008422 beta-glucosidase activity(GO:0008422)
1.0 5.9 GO:0070728 leucine binding(GO:0070728)
1.0 3.9 GO:0009378 four-way junction helicase activity(GO:0009378)
1.0 3.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.0 10.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
1.0 2.9 GO:0004630 phospholipase D activity(GO:0004630)
0.9 26.5 GO:0071949 FAD binding(GO:0071949)
0.9 3.7 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.9 2.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.9 6.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.9 6.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.9 8.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.9 1.8 GO:0032427 GBD domain binding(GO:0032427)
0.9 18.0 GO:0050811 GABA receptor binding(GO:0050811)
0.9 2.7 GO:0005042 netrin receptor activity(GO:0005042)
0.9 4.4 GO:0008410 CoA-transferase activity(GO:0008410)
0.9 4.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.9 18.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.9 3.5 GO:0030492 hemoglobin binding(GO:0030492)
0.9 13.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.9 12.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.9 17.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.9 4.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.9 7.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.9 2.6 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.9 13.7 GO:0051787 misfolded protein binding(GO:0051787)
0.9 12.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.8 6.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.8 2.5 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.8 9.3 GO:0050700 CARD domain binding(GO:0050700)
0.8 5.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.8 4.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.8 4.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8 2.5 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.8 3.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.8 6.5 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.8 8.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.8 278.0 GO:0005096 GTPase activator activity(GO:0005096)
0.8 9.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.8 6.3 GO:0031433 telethonin binding(GO:0031433)
0.8 2.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.8 3.1 GO:0001031 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.8 3.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.8 15.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.8 14.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.8 2.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.8 15.3 GO:0005522 profilin binding(GO:0005522)
0.8 8.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.8 6.9 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.8 6.1 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.8 7.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.8 15.0 GO:0042056 chemoattractant activity(GO:0042056)
0.7 9.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.7 72.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.7 2.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.7 5.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.7 1.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.7 7.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.7 3.7 GO:0016841 ammonia-lyase activity(GO:0016841)
0.7 2.9 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.7 15.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7 8.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.7 4.3 GO:0042608 T cell receptor binding(GO:0042608)
0.7 8.6 GO:0008097 5S rRNA binding(GO:0008097)
0.7 24.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.7 9.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.7 43.7 GO:0070412 R-SMAD binding(GO:0070412)
0.7 7.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.7 4.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.7 3.5 GO:0017018 myosin phosphatase activity(GO:0017018)
0.7 3.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.7 6.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.7 4.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.7 8.8 GO:0008199 ferric iron binding(GO:0008199)
0.7 8.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.7 12.8 GO:0048156 tau protein binding(GO:0048156)
0.7 4.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.7 18.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.7 5.3 GO:0000405 bubble DNA binding(GO:0000405)
0.7 7.9 GO:1990239 steroid hormone binding(GO:1990239)
0.7 12.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.7 2.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.7 2.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.6 3.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 10.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.6 16.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.6 3.8 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.6 1.9 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.6 120.0 GO:0005057 receptor signaling protein activity(GO:0005057)
0.6 2.5 GO:0043237 laminin-1 binding(GO:0043237)
0.6 17.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.6 2.5 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.6 7.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.6 2.5 GO:0099609 microtubule lateral binding(GO:0099609)
0.6 6.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.6 3.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.6 7.3 GO:0051434 BH3 domain binding(GO:0051434)
0.6 3.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.6 9.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.6 12.7 GO:0031005 filamin binding(GO:0031005)
0.6 4.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.6 11.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.6 13.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.6 3.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 9.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.6 6.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.6 2.9 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.6 1.7 GO:0004967 glucagon receptor activity(GO:0004967)
0.6 2.3 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.6 1.7 GO:0031711 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.6 2.2 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.6 3.9 GO:0008417 fucosyltransferase activity(GO:0008417)
0.6 2.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.6 5.0 GO:0004969 histamine receptor activity(GO:0004969)
0.6 10.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.6 1.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.5 2.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.5 11.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.5 26.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.5 12.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.5 61.1 GO:0005179 hormone activity(GO:0005179)
0.5 10.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.5 12.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.5 2.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.5 1.6 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.5 2.1 GO:0004966 galanin receptor activity(GO:0004966)
0.5 6.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.5 1.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.5 1.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.5 4.1 GO:0015232 heme transporter activity(GO:0015232)
0.5 29.4 GO:0043621 protein self-association(GO:0043621)
0.5 1.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.5 11.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.5 14.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 6.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 9.3 GO:0005272 sodium channel activity(GO:0005272)
0.5 1.5 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.5 5.3 GO:0015643 toxic substance binding(GO:0015643)
0.5 1.9 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.5 1.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.5 6.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.5 2.8 GO:0004359 glutaminase activity(GO:0004359)
0.5 11.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.5 3.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.5 7.4 GO:0016594 glycine binding(GO:0016594)
0.5 8.3 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.5 6.8 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.4 1.8 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.4 2.6 GO:0039552 RIG-I binding(GO:0039552)
0.4 4.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.4 11.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.4 2.6 GO:0004111 creatine kinase activity(GO:0004111)
0.4 0.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.4 1.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4 2.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.4 5.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.4 8.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.4 1.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 1.7 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.4 4.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.4 2.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.4 5.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 0.8 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.4 10.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 3.6 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 1.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.4 1.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 3.1 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.4 0.4 GO:1902271 D3 vitamins binding(GO:1902271)
0.4 5.1 GO:0070700 BMP receptor binding(GO:0070700)
0.4 1.9 GO:0031996 thioesterase binding(GO:0031996)
0.4 7.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.4 1.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.4 2.6 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.4 4.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.4 6.3 GO:0001614 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4 24.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.4 4.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 20.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.4 4.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 2.5 GO:0032027 myosin light chain binding(GO:0032027)
0.4 0.7 GO:0004040 amidase activity(GO:0004040)
0.4 1.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.4 14.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.4 58.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 1.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 30.3 GO:0019210 kinase inhibitor activity(GO:0019210)
0.3 3.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 33.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 5.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 1.7 GO:0070097 delta-catenin binding(GO:0070097)
0.3 4.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 5.4 GO:0000150 recombinase activity(GO:0000150)
0.3 0.7 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.3 1.7 GO:0030553 cGMP binding(GO:0030553)
0.3 2.3 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.3 6.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.3 7.9 GO:0032451 demethylase activity(GO:0032451)
0.3 5.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 11.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 1.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.3 3.4 GO:0048018 receptor agonist activity(GO:0048018)
0.3 7.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 1.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.3 4.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3 0.9 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.3 0.6 GO:0022824 transmitter-gated ion channel activity(GO:0022824) transmitter-gated channel activity(GO:0022835)
0.3 1.4 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.3 2.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.3 354.3 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.3 13.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 1.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.3 4.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.3 5.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 18.9 GO:0035004 phosphatidylinositol 3-kinase activity(GO:0035004)
0.3 1.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 1.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.3 4.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.2 22.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 0.7 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2 2.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2 1.4 GO:0031013 troponin I binding(GO:0031013)
0.2 0.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 35.4 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.2 3.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 0.7 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.7 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 4.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 1.8 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2 0.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 1.2 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 26.3 GO:0005516 calmodulin binding(GO:0005516)
0.2 3.7 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.2 0.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 0.6 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.2 1.1 GO:0004046 aminoacylase activity(GO:0004046)
0.2 0.6 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.2 0.6 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 9.7 GO:0005254 chloride channel activity(GO:0005254)
0.2 0.9 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 2.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 1.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 2.3 GO:0019841 retinol binding(GO:0019841)
0.2 1.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 0.5 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.2 2.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 4.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 1.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 2.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 4.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 3.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.2 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.5 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.2 GO:0070888 E-box binding(GO:0070888)
0.1 9.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.4 GO:0008480 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 1.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.1 GO:0099589 serotonin receptor activity(GO:0099589)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 3.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.7 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 2.5 GO:0022829 wide pore channel activity(GO:0022829)
0.1 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.4 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 1.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 3.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 2.8 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0 0.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 344.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
5.2 15.5 PID S1P S1P2 PATHWAY S1P2 pathway
4.4 13.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
3.7 324.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
3.5 10.6 PID S1P S1P4 PATHWAY S1P4 pathway
3.4 325.8 PID IL4 2PATHWAY IL4-mediated signaling events
3.3 6.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
2.6 23.7 PID IL27 PATHWAY IL27-mediated signaling events
2.4 29.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
2.4 7.1 ST STAT3 PATHWAY STAT3 Pathway
2.2 32.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
2.1 51.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
2.0 27.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
1.8 29.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.8 77.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
1.7 106.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
1.7 6.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
1.7 17.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
1.7 13.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
1.6 6.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
1.6 1.6 ST GAQ PATHWAY G alpha q Pathway
1.5 47.5 PID IL1 PATHWAY IL1-mediated signaling events
1.5 3.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
1.5 10.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
1.5 37.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
1.5 7.4 ST JAK STAT PATHWAY Jak-STAT Pathway
1.5 56.6 PID BCR 5PATHWAY BCR signaling pathway
1.4 15.8 PID ALK1 PATHWAY ALK1 signaling events
1.4 12.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
1.4 19.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
1.4 9.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
1.4 73.0 PID IL12 2PATHWAY IL12-mediated signaling events
1.3 12.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
1.2 41.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
1.2 82.9 PID HNF3A PATHWAY FOXA1 transcription factor network
1.0 51.4 PID ARF6 PATHWAY Arf6 signaling events
1.0 44.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.0 13.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
1.0 35.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.9 20.8 PID IFNG PATHWAY IFN-gamma pathway
0.9 17.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.9 2.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.9 14.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.8 149.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.8 15.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.8 4.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.8 26.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.8 8.1 PID EPO PATHWAY EPO signaling pathway
0.8 19.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.7 14.2 PID IL3 PATHWAY IL3-mediated signaling events
0.7 8.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.7 12.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.7 16.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.7 16.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.7 3.3 NABA COLLAGENS Genes encoding collagen proteins
0.6 5.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.6 3.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6 15.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.6 2.4 PID IL23 PATHWAY IL23-mediated signaling events
0.6 25.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.6 23.8 PID P53 REGULATION PATHWAY p53 pathway
0.6 17.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5 5.4 PID CONE PATHWAY Visual signal transduction: Cones
0.5 35.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.5 132.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5 8.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.5 32.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.5 33.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.5 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.5 29.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.5 12.6 ST GA13 PATHWAY G alpha 13 Pathway
0.5 7.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.5 2.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5 25.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.4 2.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 8.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.4 14.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.4 3.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.4 6.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.4 3.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.4 22.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 7.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.4 28.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.4 4.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 18.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.3 2.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.3 8.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 1.7 PID CD40 PATHWAY CD40/CD40L signaling
0.3 9.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 1.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.3 31.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.3 12.6 PID LKB1 PATHWAY LKB1 signaling events
0.3 2.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.3 4.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 20.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 14.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 1.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 2.7 PID RAS PATHWAY Regulation of Ras family activation
0.2 10.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 1.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 4.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 2.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 2.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 5.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 7.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 7.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 43.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 4.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 5.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 5.8 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.0 PID CDC42 PATHWAY CDC42 signaling events
0.1 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
18.3 384.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
11.2 123.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
10.5 73.7 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
6.8 13.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
5.5 27.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
5.3 457.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
3.6 7.2 REACTOME SIGNALING BY NOTCH Genes involved in Signaling by NOTCH
3.2 6.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
3.2 6.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
3.1 55.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
2.7 53.8 REACTOME DEFENSINS Genes involved in Defensins
2.6 49.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.6 36.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
2.4 35.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
2.4 58.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
2.2 10.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
2.1 33.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
2.0 26.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
1.9 28.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.8 24.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
1.8 3.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.8 42.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.7 5.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
1.6 70.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
1.6 3.3 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
1.6 4.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.6 20.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.5 7.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.5 6.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
1.5 48.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
1.5 26.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
1.5 45.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
1.5 8.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
1.4 5.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.4 15.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
1.4 32.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
1.4 14.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.4 63.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
1.3 80.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
1.3 21.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
1.3 29.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
1.3 55.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
1.3 27.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
1.3 33.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.2 12.5 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
1.1 29.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
1.1 9.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
1.1 9.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.1 10.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.1 18.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
1.1 8.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.1 22.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.0 25.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
1.0 59.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
1.0 21.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.0 7.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.0 3.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
1.0 33.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.9 5.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.9 4.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.9 4.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.9 3.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.9 16.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.9 4.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.9 34.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.9 14.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.9 38.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.9 21.4 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.8 24.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.8 31.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.8 8.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.8 40.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.8 7.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.8 73.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.8 11.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.8 6.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.8 4.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.8 9.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.7 11.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.7 11.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 32.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.7 9.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.7 15.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.7 305.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.7 7.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.7 6.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.7 10.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.7 16.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.7 28.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.6 36.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.6 90.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.6 4.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.6 3.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.6 11.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.6 13.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.6 5.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.6 15.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.5 6.0 REACTOME OPSINS Genes involved in Opsins
0.5 20.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 3.6 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.5 92.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.5 10.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.5 65.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.5 3.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.5 10.7 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.5 12.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 9.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.5 13.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.4 31.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.4 4.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.4 21.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.4 8.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.4 13.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.4 5.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.4 9.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 5.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 29.8 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.4 2.6 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.4 7.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.4 31.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.3 5.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 6.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 10.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 1.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.3 21.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 2.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 1.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.3 4.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 9.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3 13.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 5.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 9.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 2.8 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.2 5.4 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 8.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 1.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 2.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 1.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.2 5.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 1.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 1.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 3.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 3.8 REACTOME PI3K CASCADE Genes involved in PI3K Cascade
0.2 3.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 0.7 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.2 4.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 2.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 1.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 0.8 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 3.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 8.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 14.0 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling
0.1 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 4.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 6.4 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.1 0.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 3.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 3.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.8 REACTOME NEUROTRANSMITTER RELEASE CYCLE Genes involved in Neurotransmitter Release Cycle