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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SMAD4

Z-value: 10.75

Motif logo

Transcription factors associated with SMAD4

Gene Symbol Gene ID Gene Info
ENSG00000141646.14 SMAD4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD4hg38_v1_chr18_+_51030100_510302700.082.2e-01Click!

Activity profile of SMAD4 motif

Sorted Z-values of SMAD4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_117199363 41.22 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
transgelin
chr14_-_105743032 40.45 ENST00000390548.6
ENST00000390549.6
ENST00000390542.6
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_22904850 34.84 ENST00000390324.2
immunoglobulin lambda joining 3
chr6_+_33080445 33.12 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr2_-_88857582 32.86 ENST00000390237.2
immunoglobulin kappa constant
chr11_-_111923722 32.03 ENST00000527950.5
crystallin alpha B
chr6_-_33080710 29.36 ENST00000419277.5
major histocompatibility complex, class II, DP alpha 1
chr2_-_218002988 26.44 ENST00000682258.1
ENST00000446903.5
tensin 1
chr5_-_42825884 25.55 ENST00000506577.5
selenoprotein P
chr14_-_105771405 22.25 ENST00000641136.1
ENST00000390551.6
immunoglobulin heavy constant gamma 3 (G3m marker)
chr7_+_94394886 22.11 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr22_+_22899481 20.86 ENST00000390322.2
immunoglobulin lambda joining 2
chr1_-_30757767 20.29 ENST00000294507.4
lysosomal protein transmembrane 5
chr5_-_151686908 20.03 ENST00000231061.9
secreted protein acidic and cysteine rich
chr8_-_119592954 19.73 ENST00000522167.5
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr22_+_22895368 19.65 ENST00000390321.2
immunoglobulin lambda constant 1
chr6_+_32741382 19.41 ENST00000374940.4
major histocompatibility complex, class II, DQ alpha 2
chr5_+_151025343 19.20 ENST00000521632.1
glutathione peroxidase 3
chr12_-_14950606 19.08 ENST00000536592.5
Rho GDP dissociation inhibitor beta
chr22_+_30356620 19.07 ENST00000399824.6
ENST00000405659.5
coiled-coil domain containing 157
chr6_+_33075952 18.54 ENST00000418931.7
major histocompatibility complex, class II, DP beta 1
chr11_+_57598184 18.53 ENST00000677625.1
ENST00000676670.1
serpin family G member 1
chr2_+_89862438 17.56 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr11_+_72216774 17.42 ENST00000619261.4
ENST00000454954.6
ENST00000541003.5
ENST00000539412.5
ENST00000298223.11
ENST00000536778.5
ENST00000535625.5
ENST00000321324.11
folate receptor beta
chr22_+_22697789 17.35 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr22_+_22431949 17.31 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr2_+_238138661 17.24 ENST00000409223.2
kelch like family member 30
chr12_-_14951106 17.16 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr3_+_52495330 16.97 ENST00000321725.10
stabilin 1
chr11_-_111910790 16.96 ENST00000533280.6
crystallin alpha B
chr19_-_36152427 16.63 ENST00000589154.1
ENST00000292907.8
cytochrome c oxidase subunit 7A1
chr17_+_18225582 16.42 ENST00000316843.9
LLGL scribble cell polarity complex component 1
chr11_-_111910830 16.38 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr2_+_15940537 16.34 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr11_-_111910888 16.30 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chrX_+_38561530 16.13 ENST00000378482.7
ENST00000286824.6
tetraspanin 7
chr19_-_8832286 15.33 ENST00000601372.6
zinc finger protein 558
chr14_-_105863862 15.08 ENST00000488476.1
immunoglobulin heavy joining 5
chr2_+_112275588 15.06 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr10_+_26216665 14.95 ENST00000259271.7
glutamate decarboxylase 2
chr10_-_88952763 14.72 ENST00000224784.10
actin alpha 2, smooth muscle
chr9_+_121268060 14.61 ENST00000373808.8
ENST00000432226.7
ENST00000449733.7
gelsolin
chr1_+_228458095 14.28 ENST00000620438.1
H2B.U histone 1
chr1_-_230745574 14.26 ENST00000681269.1
angiotensinogen
chr22_+_22758698 14.13 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr9_-_107489754 14.13 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr12_+_123671105 13.66 ENST00000680574.1
ENST00000426174.6
ENST00000679504.1
ENST00000303372.7
tectonic family member 2
chr12_-_48971723 13.58 ENST00000301061.9
Wnt family member 10B
chr3_+_184249621 13.36 ENST00000324557.9
ENST00000402825.7
EEF1A lysine methyltransferase 4
EEF1AKMT4-ECE2 readthrough
chr5_+_157269317 13.22 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr1_-_11805924 13.17 ENST00000418034.1
methylenetetrahydrofolate reductase
chr1_-_11805949 12.95 ENST00000376590.9
methylenetetrahydrofolate reductase
chr6_-_32941018 12.93 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chr4_+_54657918 12.57 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr1_+_204870831 12.52 ENST00000404076.5
ENST00000539706.6
neurofascin
chr2_+_241702027 12.51 ENST00000313552.11
ENST00000406941.5
inhibitor of growth family member 5
chr6_-_6320642 12.45 ENST00000451619.1
ENST00000264870.8
coagulation factor XIII A chain
chr22_+_30356974 12.38 ENST00000445005.5
ENST00000430839.5
ENST00000338306.8
coiled-coil domain containing 157
chr22_+_41560973 12.21 ENST00000306149.12
cold shock domain containing C2
chr5_+_179023794 12.15 ENST00000519896.5
ENST00000522442.1
ENST00000444149.7
zinc finger protein 879
chr1_+_46489800 12.05 ENST00000360032.4
diencephalon/mesencephalon homeobox 1
chr22_+_22327298 11.89 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr19_+_51225059 11.88 ENST00000436584.6
ENST00000421133.6
ENST00000262262.5
ENST00000391796.7
CD33 molecule
chr22_+_22792485 11.74 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr5_-_150155828 11.70 ENST00000261799.9
platelet derived growth factor receptor beta
chr11_-_117876719 11.69 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr18_+_13218195 11.67 ENST00000679167.1
low density lipoprotein receptor class A domain containing 4
chr14_-_21023318 11.43 ENST00000298684.9
ENST00000557169.5
ENST00000553563.5
NDRG family member 2
chr17_+_18225672 11.39 ENST00000621229.1
LLGL scribble cell polarity complex component 1
chr7_+_100101657 11.24 ENST00000421755.5
adaptor related protein complex 4 subunit mu 1
chr2_-_88966767 11.22 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr11_-_117876892 11.14 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr8_-_6978634 11.08 ENST00000382679.2
defensin alpha 1
chr19_+_11538844 11.07 ENST00000252456.7
calponin 1
chr19_+_45469841 11.06 ENST00000592811.5
ENST00000586615.5
FosB proto-oncogene, AP-1 transcription factor subunit
chr12_-_11269696 11.04 ENST00000381842.7
proline rich protein BstNI subfamily 3
chr12_-_12338674 11.03 ENST00000545735.1
MANSC domain containing 1
chr19_+_55675191 11.02 ENST00000270460.11
ENST00000085079.11
epsin 1
chr9_-_94639473 11.02 ENST00000375326.9
fructose-bisphosphatase 1
chr4_+_155667096 10.89 ENST00000393832.7
guanylate cyclase 1 soluble subunit alpha 1
chr17_+_42851167 10.87 ENST00000613571.1
ENST00000308423.7
amine oxidase copper containing 3
chr16_+_1533654 10.84 ENST00000566264.2
transmembrane protein 204
chr19_+_35775515 10.84 ENST00000378944.9
Rho GTPase activating protein 33
chr14_-_105940235 10.81 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr19_+_41797147 10.79 ENST00000596544.1
CEA cell adhesion molecule 3
chr9_-_34691204 10.74 ENST00000378800.3
ENST00000311925.7
C-C motif chemokine ligand 19
chrX_+_153494970 10.74 ENST00000331595.9
ENST00000431891.1
biglycan
chr22_+_22720615 10.69 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr2_+_89884740 10.67 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr22_-_29315656 10.62 ENST00000401450.3
ENST00000216101.7
RAS like family 10 member A
chr14_+_92923143 10.56 ENST00000216492.10
ENST00000334654.4
chromogranin A
chr6_-_11807045 10.56 ENST00000379415.6
androgen dependent TFPI regulating protein
chr19_+_35775530 10.43 ENST00000314737.9
ENST00000007510.8
Rho GTPase activating protein 33
chr1_-_153348825 10.33 ENST00000368739.3
ENST00000359650.10
peptidoglycan recognition protein 4
chr18_+_13217676 10.30 ENST00000679177.1
low density lipoprotein receptor class A domain containing 4
chr15_-_82647503 10.27 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr3_-_14178569 10.23 ENST00000285021.12
XPC complex subunit, DNA damage recognition and repair factor
chr14_-_21022817 10.09 ENST00000554104.5
NDRG family member 2
chr11_-_125592448 10.00 ENST00000648911.1
fasciculation and elongation protein zeta 1
chr12_-_48971680 9.99 ENST00000403957.5
Wnt family member 10B
chr17_+_15699577 9.98 ENST00000421016.5
ENST00000593105.5
ENST00000580259.5
ENST00000472486.5
ENST00000395894.6
ENST00000581529.5
ENST00000579694.5
ENST00000580393.5
ENST00000585194.5
ENST00000583566.6
ENST00000583031.5
ENST00000464847.6
zinc finger protein 286A
chr17_-_10697501 9.97 ENST00000577427.1
ENST00000255390.10
synthesis of cytochrome C oxidase 1
chr3_+_133746385 9.96 ENST00000482271.5
ENST00000402696.9
transferrin
chr18_-_55588184 9.86 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr11_-_72674394 9.77 ENST00000418754.6
ENST00000334456.10
ENST00000542969.2
phosphodiesterase 2A
chr19_-_54280498 9.76 ENST00000391746.5
leukocyte immunoglobulin like receptor B2
chr19_+_49335396 9.75 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr16_-_28538951 9.72 ENST00000324873.8
nuclear protein 1, transcriptional regulator
chr4_+_155667198 9.68 ENST00000296518.11
guanylate cyclase 1 soluble subunit alpha 1
chr17_-_42745025 9.65 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr22_-_24245059 9.64 ENST00000398292.3
ENST00000263112.11
ENST00000327365.10
ENST00000424217.1
gamma-glutamyltransferase 5
chr12_-_49843092 9.63 ENST00000333924.6
BCDIN3 domain containing RNA methyltransferase
chr8_+_28890365 9.59 ENST00000519662.5
ENST00000558662.5
ENST00000287701.15
ENST00000523613.5
ENST00000560599.5
ENST00000397358.7
homeobox containing 1
chr4_+_155666963 9.57 ENST00000455639.6
guanylate cyclase 1 soluble subunit alpha 1
chr7_+_100101556 9.57 ENST00000438383.5
ENST00000429084.5
ENST00000439416.5
adaptor related protein complex 4 subunit mu 1
chr2_+_88885397 9.53 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr19_+_41262656 9.53 ENST00000599719.5
ENST00000601309.5
heterogeneous nuclear ribonucleoprotein U like 1
chr15_-_82647960 9.48 ENST00000615198.4
cytoplasmic polyadenylation element binding protein 1
chr18_-_55588535 9.48 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
transcription factor 4
chr7_-_135510074 9.45 ENST00000428680.6
ENST00000423368.6
ENST00000451834.5
ENST00000361528.8
ENST00000541284.5
ENST00000315544.6
CCR4-NOT transcription complex subunit 4
chr2_-_89213917 9.45 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr7_-_99976017 9.42 ENST00000411734.1
ENST00000292401.9
alpha-2-glycoprotein 1, zinc-binding
chr9_-_120714457 9.39 ENST00000373930.4
multiple EGF like domains 9
chr19_-_17847962 9.35 ENST00000458235.7
ENST00000534444.1
Janus kinase 3
chr11_-_117877463 9.33 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr4_+_155666827 9.23 ENST00000511507.5
ENST00000506455.6
guanylate cyclase 1 soluble subunit alpha 1
chr22_+_22811737 9.16 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr19_-_46661132 9.16 ENST00000410105.2
ENST00000391916.7
dishevelled binding antagonist of beta catenin 3
chr7_+_100101632 9.14 ENST00000359593.9
adaptor related protein complex 4 subunit mu 1
chr6_-_32128191 9.09 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
activating transcription factor 6 beta
chr19_+_11538767 9.07 ENST00000592923.5
ENST00000535659.6
calponin 1
chr5_-_115816650 9.05 ENST00000250535.5
cysteine dioxygenase type 1
chrX_-_140505058 9.00 ENST00000370536.5
SRY-box transcription factor 3
chr14_-_106211453 8.98 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr1_-_160711803 8.89 ENST00000368045.3
ENST00000368046.8
ENST00000613788.1
CD48 molecule
chr5_-_150113344 8.81 ENST00000286301.7
ENST00000511344.1
colony stimulating factor 1 receptor
chr12_-_11269805 8.80 ENST00000538488.2
proline rich protein BstNI subfamily 3
chr1_+_26159071 8.78 ENST00000374268.5
family with sequence similarity 110 member D
chr2_-_207165923 8.75 ENST00000309446.11
Kruppel like factor 7
chr19_-_57814878 8.73 ENST00000391701.1
zinc finger protein 552
chr11_-_118342616 8.71 ENST00000392884.2
CD3d molecule
chr16_-_3256587 8.70 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV innate immuity regulator, pyrin
chr4_-_932280 8.67 ENST00000314167.9
ENST00000502656.5
ENST00000628912.1
cyclin G associated kinase
chr22_-_27801712 8.65 ENST00000302326.5
MN1 proto-oncogene, transcriptional regulator
chr1_+_152675295 8.62 ENST00000368783.1
late cornified envelope 2C
chr10_-_79949098 8.51 ENST00000372292.8
surfactant protein D
chr6_-_41895359 8.49 ENST00000373006.5
ENST00000682992.1
ubiquitin specific peptidase 49
chrX_+_18425597 8.49 ENST00000623535.2
ENST00000674046.1
cyclin dependent kinase like 5
chr2_-_217944005 8.49 ENST00000611415.4
ENST00000615025.5
ENST00000449814.1
ENST00000171887.8
tensin 1
chrX_-_66639255 8.44 ENST00000451436.6
ectodysplasin A2 receptor
chrX_+_136197039 8.36 ENST00000370683.6
four and a half LIM domains 1
chr7_+_43112593 8.34 ENST00000453890.5
ENST00000395891.7
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr12_+_53046969 8.30 ENST00000379902.7
tensin 2
chr6_-_169253835 8.30 ENST00000649844.1
ENST00000617924.6
thrombospondin 2
chr16_-_66552460 8.30 ENST00000678015.1
ENST00000569718.6
ENST00000678314.1
ENST00000562484.2
thymidine kinase 2
chr9_+_109780179 8.27 ENST00000314527.9
PALM2 and AKAP2 fusion
chrY_-_13479938 8.26 ENST00000382893.2
ENST00000382896.9
ENST00000545955.6
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr14_+_61187544 8.26 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chr19_-_54360949 8.19 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr15_+_43510945 8.15 ENST00000382031.5
microtubule associated protein 1A
chr14_-_22819721 8.14 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
solute carrier family 7 member 7
chr17_-_63700100 8.14 ENST00000578993.5
ENST00000259006.8
ENST00000583211.5
LIM domain containing 2
chrX_+_54530201 8.09 ENST00000674225.1
ENST00000336470.8
ENST00000360845.3
ENST00000674238.1
ENST00000674420.1
ENST00000674311.1
ENST00000674508.1
G protein nucleolar 3 like
chr21_+_31873010 8.07 ENST00000270112.7
hormonally up-regulated Neu-associated kinase
chr16_+_67164730 8.06 ENST00000521374.6
heat shock transcription factor 4
chr6_-_26189101 8.05 ENST00000614247.2
H4 clustered histone 4
chr12_+_53050179 8.00 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
tensin 2
chr7_+_150800403 7.99 ENST00000484928.5
transmembrane protein 176A
chr12_-_16606795 7.97 ENST00000447609.5
LIM domain only 3
chr1_-_28193873 7.95 ENST00000305392.3
ENST00000539896.1
platelet activating factor receptor
chr12_-_98644733 7.95 ENST00000299157.5
ENST00000393042.3
IKBKB interacting protein
chr7_-_16421524 7.94 ENST00000407010.7
CDP-L-ribitol pyrophosphorylase A
chr10_+_69088096 7.87 ENST00000242465.4
serglycin
chr9_+_133534697 7.87 ENST00000651351.2
ADAMTS like 2
chr12_-_16605939 7.86 ENST00000541295.5
ENST00000535535.5
LIM domain only 3
chr5_-_169301098 7.78 ENST00000519560.6
slit guidance ligand 3
chr13_+_30735523 7.77 ENST00000380490.5
arachidonate 5-lipoxygenase activating protein
chr12_-_16606102 7.77 ENST00000537304.6
LIM domain only 3
chr1_-_151146611 7.73 ENST00000341697.7
ENST00000368914.8
semaphorin 6C
chr10_+_45374204 7.71 ENST00000374391.7
arachidonate 5-lipoxygenase
chr11_+_64230726 7.70 ENST00000321460.5
DnaJ heat shock protein family (Hsp40) member C4
chr1_+_226223618 7.65 ENST00000542034.5
ENST00000366810.6
Mix paired-like homeobox
chr11_+_124622853 7.65 ENST00000441174.8
ENST00000531667.5
transforming growth factor beta regulator 1
chr2_+_30231524 7.65 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr3_+_42502592 7.65 ENST00000438259.6
ENST00000543411.5
ENST00000439731.5
ENST00000325123.5
vasoactive intestinal peptide receptor 1
chr1_-_207052980 7.59 ENST00000367084.1
YOD1 deubiquitinase
chr18_-_55401751 7.58 ENST00000537856.7
transcription factor 4
chr19_+_16888991 7.57 ENST00000248076.4
F2R like thrombin or trypsin receptor 3
chr19_+_40717091 7.53 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr2_+_17878637 7.49 ENST00000304101.9
potassium voltage-gated channel modifier subfamily S member 3
chr16_+_67164780 7.48 ENST00000517685.5
ENST00000584272.5
heat shock transcription factor 4
chr17_+_44308573 7.45 ENST00000590941.5
ENST00000225441.11
ENST00000426726.8
RUN domain containing 3A
chr15_+_32641665 7.42 ENST00000300175.8
ENST00000413748.6
ENST00000494364.5
ENST00000497208.5
secretogranin V
chr3_+_121835197 7.41 ENST00000273668.7
ENST00000451944.2
ELL associated factor 2
chr1_-_11805294 7.41 ENST00000413656.5
ENST00000376592.6
ENST00000376585.6
methylenetetrahydrofolate reductase
chr12_-_16600703 7.40 ENST00000616247.4
LIM domain only 3
chr17_-_58544315 7.31 ENST00000671766.1
ENST00000672673.2
ENST00000321691.3
septin 4
chrX_-_50814095 7.30 ENST00000376020.8
shroom family member 4
chr19_-_54281145 7.30 ENST00000434421.5
ENST00000391749.4
leukocyte immunoglobulin like receptor B2
chr1_+_156153568 7.29 ENST00000368284.5
ENST00000368286.6
ENST00000368285.8
ENST00000438830.5
semaphorin 4A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.1 36.2 GO:0071461 cellular response to redox state(GO:0071461)
7.9 23.6 GO:0071464 cellular response to hydrostatic pressure(GO:0071464)
7.7 7.7 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
6.3 18.8 GO:0006982 response to lipid hydroperoxide(GO:0006982)
6.2 24.9 GO:0071231 cellular response to folic acid(GO:0071231)
6.2 18.5 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
5.6 33.5 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
4.9 19.6 GO:1905224 clathrin-coated pit assembly(GO:1905224)
4.9 14.7 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
4.8 81.7 GO:0007021 tubulin complex assembly(GO:0007021)
4.8 14.3 GO:0014873 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
4.7 14.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
4.4 31.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
4.4 13.2 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
4.3 13.0 GO:0001300 chronological cell aging(GO:0001300)
4.3 13.0 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
4.3 12.9 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
4.2 4.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
4.2 12.6 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662)
3.9 27.4 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
3.7 11.1 GO:0035915 pore formation in membrane of other organism(GO:0035915)
3.6 10.7 GO:2000547 dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
3.4 10.3 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
3.4 20.4 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
3.3 10.0 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
3.2 25.6 GO:0001887 selenium compound metabolic process(GO:0001887)
3.0 9.1 GO:0042412 taurine biosynthetic process(GO:0042412)
2.9 14.7 GO:0090131 mesenchyme migration(GO:0090131)
2.9 14.6 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
2.9 8.7 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
2.9 20.0 GO:0033591 response to L-ascorbic acid(GO:0033591)
2.8 11.0 GO:0005986 sucrose biosynthetic process(GO:0005986)
2.8 13.8 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
2.7 10.9 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
2.6 7.9 GO:0033364 mast cell secretory granule organization(GO:0033364)
2.6 2.6 GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
2.5 7.6 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
2.4 9.8 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
2.4 36.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
2.4 7.3 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
2.3 7.0 GO:0006311 meiotic gene conversion(GO:0006311)
2.3 9.3 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
2.3 6.9 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
2.2 6.7 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859)
2.2 165.5 GO:0006910 phagocytosis, recognition(GO:0006910)
2.2 11.0 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
2.2 6.5 GO:0060005 vestibular reflex(GO:0060005)
2.2 28.1 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
2.1 8.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
2.1 6.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
2.1 8.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
1.9 5.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.9 13.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.9 5.6 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.8 22.1 GO:0043589 skin morphogenesis(GO:0043589)
1.8 10.8 GO:0008218 bioluminescence(GO:0008218)
1.8 5.3 GO:0060018 astrocyte fate commitment(GO:0060018)
1.8 5.3 GO:0090273 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
1.8 3.5 GO:0090264 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
1.8 8.8 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
1.8 5.3 GO:0014016 noradrenergic neuron development(GO:0003358) neuroblast differentiation(GO:0014016) spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) regulation of timing of neuron differentiation(GO:0060164) olfactory pit development(GO:0060166)
1.7 8.7 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.7 5.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
1.7 5.0 GO:0019075 virus maturation(GO:0019075)
1.7 28.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.7 10.0 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
1.6 16.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.6 4.9 GO:0036343 psychomotor behavior(GO:0036343)
1.6 4.9 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.6 14.5 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.6 6.4 GO:1902023 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
1.6 8.0 GO:0042360 vitamin E metabolic process(GO:0042360)
1.6 8.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
1.6 6.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
1.5 10.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
1.5 7.7 GO:2000382 positive regulation of mesoderm development(GO:2000382)
1.5 18.1 GO:0048251 elastic fiber assembly(GO:0048251)
1.5 4.5 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
1.5 4.5 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
1.5 7.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
1.5 4.4 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
1.5 18.9 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
1.4 18.7 GO:0045059 positive thymic T cell selection(GO:0045059)
1.4 7.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.4 8.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.4 12.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.4 2.8 GO:0060431 primary lung bud formation(GO:0060431)
1.4 8.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
1.4 5.5 GO:0002644 negative regulation of tolerance induction(GO:0002644)
1.4 4.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
1.4 23.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.4 5.4 GO:0009822 alkaloid catabolic process(GO:0009822) calcitriol biosynthetic process from calciol(GO:0036378)
1.3 12.1 GO:0008343 adult feeding behavior(GO:0008343)
1.3 2.6 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
1.3 29.9 GO:0006895 Golgi to endosome transport(GO:0006895)
1.3 5.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.3 20.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
1.3 8.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
1.3 1.3 GO:0034756 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) response to iron ion starvation(GO:1990641)
1.2 7.5 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
1.2 8.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.2 2.4 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
1.2 11.7 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
1.2 3.5 GO:0061011 hepatic duct development(GO:0061011)
1.1 6.9 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
1.1 107.8 GO:0006958 complement activation, classical pathway(GO:0006958)
1.1 3.4 GO:0060374 mast cell differentiation(GO:0060374)
1.1 10.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
1.1 119.6 GO:0031295 T cell costimulation(GO:0031295)
1.1 3.2 GO:0097272 ammonia homeostasis(GO:0097272)
1.1 3.2 GO:0071529 cementum mineralization(GO:0071529)
1.1 3.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
1.1 12.7 GO:0006824 cobalt ion transport(GO:0006824)
1.1 3.2 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
1.1 2.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
1.0 3.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
1.0 4.1 GO:2001034 histone H3-K36 dimethylation(GO:0097676) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
1.0 6.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
1.0 3.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
1.0 15.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
1.0 16.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.0 10.7 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.0 15.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.9 7.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.9 4.7 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.9 3.8 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.9 2.8 GO:0051365 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.9 8.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.9 14.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.9 3.6 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.9 4.5 GO:0001555 oocyte growth(GO:0001555)
0.9 6.3 GO:1901509 branch elongation involved in ureteric bud branching(GO:0060681) regulation of endothelial tube morphogenesis(GO:1901509)
0.9 3.6 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.9 2.7 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.9 1.8 GO:0048859 formation of anatomical boundary(GO:0048859)
0.9 6.9 GO:0019732 antifungal humoral response(GO:0019732)
0.9 9.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.9 2.6 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.8 2.5 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.8 1.7 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.8 9.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.8 4.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.8 5.8 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.8 2.5 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.8 1.6 GO:0021834 embryonic olfactory bulb interneuron precursor migration(GO:0021831) chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.8 9.4 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.8 1.6 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.8 1.5 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.8 3.0 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.8 3.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.7 3.7 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.7 3.0 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.7 10.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.7 2.9 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.7 5.8 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.7 4.3 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.7 5.1 GO:0015705 iodide transport(GO:0015705)
0.7 2.9 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.7 24.3 GO:0018149 peptide cross-linking(GO:0018149)
0.7 2.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.7 4.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.7 3.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.7 5.6 GO:0035524 proline transmembrane transport(GO:0035524)
0.7 6.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.7 10.3 GO:0007530 sex determination(GO:0007530)
0.7 2.7 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.7 3.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.7 4.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.7 5.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.7 3.4 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.7 3.3 GO:0007412 axon target recognition(GO:0007412)
0.7 3.9 GO:2001206 positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206)
0.7 3.9 GO:0050893 sensory processing(GO:0050893)
0.6 8.4 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.6 4.5 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.6 4.5 GO:0035093 piRNA metabolic process(GO:0034587) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.6 3.9 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.6 17.2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.6 8.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.6 4.5 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.6 11.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.6 1.9 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.6 1.9 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.6 1.9 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.6 8.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.6 1.8 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.6 6.7 GO:0046689 response to mercury ion(GO:0046689)
0.6 3.0 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.6 3.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.6 1.8 GO:0000103 sulfate assimilation(GO:0000103)
0.6 2.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.6 7.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.6 1.2 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.6 88.2 GO:0002377 immunoglobulin production(GO:0002377)
0.6 1.2 GO:0070428 nitric oxide production involved in inflammatory response(GO:0002537) negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.6 6.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.6 15.7 GO:0014850 response to muscle activity(GO:0014850)
0.6 4.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.6 4.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.6 1.7 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.6 4.5 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6 2.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.6 2.8 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.5 4.9 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.5 2.1 GO:0021759 globus pallidus development(GO:0021759)
0.5 5.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.5 2.7 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.5 2.6 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.5 3.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.5 6.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.5 2.6 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.5 4.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.5 3.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 13.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.5 2.0 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.5 4.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.5 3.0 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 7.0 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.5 10.1 GO:0060019 radial glial cell differentiation(GO:0060019)
0.5 11.4 GO:0006825 copper ion transport(GO:0006825)
0.5 1.0 GO:0046643 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.5 9.7 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.5 4.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.5 1.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.5 3.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.5 8.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.5 3.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.5 4.2 GO:0035542 endosomal vesicle fusion(GO:0034058) regulation of SNARE complex assembly(GO:0035542) positive regulation of early endosome to late endosome transport(GO:2000643)
0.5 2.8 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.5 1.8 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.5 9.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.5 2.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.5 1.8 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.5 6.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.5 2.7 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.5 2.3 GO:0030259 lipid glycosylation(GO:0030259)
0.5 4.1 GO:0070475 rRNA base methylation(GO:0070475)
0.4 27.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.4 1.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 8.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 4.0 GO:0060346 bone trabecula formation(GO:0060346)
0.4 3.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.4 12.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4 3.0 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.4 10.8 GO:0051412 response to corticosterone(GO:0051412)
0.4 1.3 GO:0061743 motor learning(GO:0061743)
0.4 1.7 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.4 3.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.4 9.7 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.4 5.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.4 5.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 4.6 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.4 1.3 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.4 7.1 GO:0007398 ectoderm development(GO:0007398)
0.4 16.7 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.4 12.1 GO:0048665 neuron fate specification(GO:0048665)
0.4 2.1 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.4 2.4 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.4 2.4 GO:0061143 alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.4 7.9 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.4 4.0 GO:0072540 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 cell lineage commitment(GO:0072540)
0.4 9.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.4 13.3 GO:0010165 response to X-ray(GO:0010165)
0.4 9.7 GO:0045730 respiratory burst(GO:0045730)
0.4 3.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.4 7.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.4 25.5 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.4 6.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.4 6.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.4 29.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.4 3.0 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.4 2.9 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4 1.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.4 2.9 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.4 1.4 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.4 3.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.3 1.7 GO:0097155 embryonic heart tube left/right pattern formation(GO:0060971) fasciculation of sensory neuron axon(GO:0097155)
0.3 2.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.3 1.4 GO:0032700 negative regulation of interleukin-17 production(GO:0032700)
0.3 5.7 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.3 2.4 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.3 3.7 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.3 4.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 3.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.3 1.9 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.3 1.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.3 3.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.3 15.6 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.3 6.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.3 2.5 GO:0006013 mannose metabolic process(GO:0006013)
0.3 1.8 GO:0051945 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.3 3.9 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.3 3.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 3.8 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.3 3.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 4.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.3 2.6 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.3 12.8 GO:0010761 fibroblast migration(GO:0010761)
0.3 1.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 1.7 GO:0007506 gonadal mesoderm development(GO:0007506)
0.3 2.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.3 3.0 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.3 5.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.3 5.2 GO:0003170 heart valve development(GO:0003170)
0.3 3.0 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 1.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 3.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.3 4.0 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.3 1.3 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 30.7 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.3 2.6 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.3 2.9 GO:0010572 positive regulation of platelet activation(GO:0010572) regulation of integrin activation(GO:0033623)
0.3 6.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.3 5.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 1.3 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.3 1.0 GO:1901098 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.2 4.7 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.2 7.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.2 7.3 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.2 0.4 GO:0009820 alkaloid metabolic process(GO:0009820)
0.2 5.9 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.2 2.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.2 4.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 2.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.9 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 3.8 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.2 1.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 1.5 GO:0090656 t-circle formation(GO:0090656)
0.2 5.0 GO:0001502 cartilage condensation(GO:0001502)
0.2 2.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.2 2.7 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.2 0.8 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.2 0.6 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.2 3.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 4.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.2 5.0 GO:0014002 astrocyte development(GO:0014002)
0.2 0.8 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.2 7.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 1.7 GO:0007320 insemination(GO:0007320)
0.2 7.0 GO:0016233 telomere capping(GO:0016233)
0.2 5.8 GO:0015695 organic cation transport(GO:0015695)
0.2 9.1 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2 2.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 0.9 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.2 5.0 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.2 3.3 GO:0048536 spleen development(GO:0048536)
0.2 1.0 GO:0072592 oxygen metabolic process(GO:0072592)
0.2 2.0 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 9.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 10.7 GO:0030574 collagen catabolic process(GO:0030574)
0.2 5.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 0.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 6.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 4.8 GO:0015813 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.2 2.8 GO:0006525 arginine metabolic process(GO:0006525)
0.2 3.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 5.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.2 0.6 GO:0002933 lipid hydroxylation(GO:0002933)
0.2 1.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.2 2.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 3.0 GO:0001964 startle response(GO:0001964)
0.1 6.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.7 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 5.2 GO:0045453 bone resorption(GO:0045453)
0.1 1.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 2.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 4.4 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 3.1 GO:0010002 cardioblast differentiation(GO:0010002)
0.1 6.6 GO:0010107 potassium ion import(GO:0010107)
0.1 1.9 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.4 GO:2000302 positive regulation of synaptic vesicle priming(GO:0010808) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 1.6 GO:0006069 ethanol oxidation(GO:0006069)
0.1 2.2 GO:0070207 protein homotrimerization(GO:0070207)
0.1 2.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 8.7 GO:0051899 membrane depolarization(GO:0051899)
0.1 3.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.2 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.1 6.5 GO:0042303 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.1 6.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 3.4 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.2 GO:0006029 proteoglycan metabolic process(GO:0006029)
0.1 0.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 5.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.4 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.1 3.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 6.2 GO:0042073 intraciliary transport(GO:0042073)
0.1 1.8 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.1 1.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 4.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 5.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.7 GO:0006568 tryptophan metabolic process(GO:0006568)
0.1 0.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 2.3 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 2.0 GO:0097352 autophagosome maturation(GO:0097352)
0.1 3.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 3.2 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) negative regulation of leukocyte proliferation(GO:0070664)
0.1 3.0 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.1 4.5 GO:0006968 cellular defense response(GO:0006968)
0.1 0.3 GO:0002829 negative regulation of type 2 immune response(GO:0002829) negative regulation of interleukin-13 production(GO:0032696)
0.1 4.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.6 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 0.8 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 1.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 6.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 2.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.1 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.1 1.1 GO:0048485 sympathetic nervous system development(GO:0048485)
0.1 2.6 GO:0033344 cholesterol efflux(GO:0033344)
0.1 2.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.4 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.1 2.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.8 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.1 0.9 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 0.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 3.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 2.9 GO:0007602 phototransduction(GO:0007602)
0.1 1.8 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 7.9 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 2.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 3.1 GO:0001523 retinoid metabolic process(GO:0001523)
0.1 4.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.1 5.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.9 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 2.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 2.6 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 2.8 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 2.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 2.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 20.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.6 GO:0060612 adipose tissue development(GO:0060612)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.8 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 123.2 GO:0042613 MHC class II protein complex(GO:0042613)
5.1 81.7 GO:0097512 cardiac myofibril(GO:0097512)
4.9 14.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
4.6 27.8 GO:0000137 Golgi cis cisterna(GO:0000137)
4.3 13.0 GO:0072563 endothelial microparticle(GO:0072563)
3.7 29.9 GO:0000138 Golgi trans cisterna(GO:0000138)
3.0 161.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
2.6 10.2 GO:0071942 XPC complex(GO:0071942)
2.5 12.5 GO:0097454 Schwann cell microvillus(GO:0097454)
2.4 14.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
2.0 6.0 GO:0097679 other organism cytoplasm(GO:0097679)
1.9 5.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.8 19.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.8 7.0 GO:0000801 central element(GO:0000801)
1.7 7.0 GO:1990879 CST complex(GO:1990879)
1.7 15.6 GO:0044294 dendritic growth cone(GO:0044294)
1.7 22.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.7 5.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.6 14.2 GO:0071953 elastic fiber(GO:0071953)
1.6 20.4 GO:0060077 inhibitory synapse(GO:0060077)
1.5 8.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.4 10.0 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
1.4 9.7 GO:0032010 phagolysosome(GO:0032010)
1.3 4.0 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
1.3 4.0 GO:0071821 FANCM-MHF complex(GO:0071821)
1.2 6.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
1.2 11.0 GO:0042629 mast cell granule(GO:0042629)
1.2 3.5 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.1 3.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
1.1 10.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.0 15.7 GO:0030478 actin cap(GO:0030478)
1.0 5.2 GO:0070847 core mediator complex(GO:0070847)
1.0 24.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.0 11.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.9 1.8 GO:0042599 lamellar body(GO:0042599)
0.9 17.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.8 5.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.8 20.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.8 4.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.8 3.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.8 14.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.7 13.7 GO:0036038 MKS complex(GO:0036038)
0.7 1.4 GO:0031906 late endosome lumen(GO:0031906)
0.7 10.6 GO:0042583 chromaffin granule(GO:0042583)
0.7 16.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.6 3.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.6 6.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.6 3.6 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.6 4.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.6 2.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.6 3.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 41.8 GO:0005581 collagen trimer(GO:0005581)
0.6 2.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.6 9.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.6 5.0 GO:0000813 ESCRT I complex(GO:0000813)
0.5 2.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.5 3.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.5 4.5 GO:0033391 mRNA cap binding complex(GO:0005845) chromatoid body(GO:0033391)
0.5 4.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.5 17.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.5 30.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5 6.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.5 17.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.5 5.2 GO:0060170 ciliary membrane(GO:0060170)
0.5 4.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.4 9.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.4 5.7 GO:0017119 Golgi transport complex(GO:0017119)
0.4 64.1 GO:0072562 blood microparticle(GO:0072562)
0.4 2.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.4 54.2 GO:0043202 lysosomal lumen(GO:0043202)
0.4 10.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 11.8 GO:0035580 specific granule lumen(GO:0035580)
0.4 7.9 GO:0042588 zymogen granule(GO:0042588)
0.4 3.0 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 4.6 GO:0000815 ESCRT III complex(GO:0000815)
0.3 4.2 GO:0030897 HOPS complex(GO:0030897)
0.3 13.1 GO:0090544 BAF-type complex(GO:0090544)
0.3 9.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.3 3.7 GO:0060171 stereocilium membrane(GO:0060171)
0.3 3.0 GO:0045180 basal cortex(GO:0045180)
0.3 3.2 GO:0005614 interstitial matrix(GO:0005614)
0.3 4.8 GO:0016342 catenin complex(GO:0016342)
0.3 6.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 4.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 2.8 GO:1990909 Wnt signalosome(GO:1990909)
0.3 35.5 GO:0042734 presynaptic membrane(GO:0042734)
0.3 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 6.1 GO:0005605 basal lamina(GO:0005605)
0.3 9.0 GO:0009925 basal plasma membrane(GO:0009925)
0.3 3.5 GO:0042101 T cell receptor complex(GO:0042101)
0.3 5.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.3 3.0 GO:0070449 elongin complex(GO:0070449)
0.3 2.1 GO:0072487 MSL complex(GO:0072487)
0.3 6.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 53.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 16.6 GO:0001772 immunological synapse(GO:0001772)
0.3 8.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 1.3 GO:0045179 apical cortex(GO:0045179)
0.3 14.3 GO:0005604 basement membrane(GO:0005604)
0.2 2.9 GO:0016013 syntrophin complex(GO:0016013)
0.2 14.0 GO:0043235 receptor complex(GO:0043235)
0.2 16.8 GO:0005796 Golgi lumen(GO:0005796)
0.2 15.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 9.1 GO:0001533 cornified envelope(GO:0001533)
0.2 6.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 30.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 14.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 7.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.2 3.5 GO:0000242 pericentriolar material(GO:0000242)
0.2 9.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 7.0 GO:0032590 dendrite membrane(GO:0032590)
0.2 1.5 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.2 15.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 6.6 GO:0045095 keratin filament(GO:0045095)
0.2 3.9 GO:0005682 U5 snRNP(GO:0005682)
0.2 1.3 GO:0072687 meiotic spindle(GO:0072687)
0.2 1.6 GO:0097443 sorting endosome(GO:0097443)
0.2 0.8 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 4.7 GO:0008305 integrin complex(GO:0008305)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.1 1.3 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.0 GO:1990130 Iml1 complex(GO:1990130)
0.1 4.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 15.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 18.9 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.7 GO:0005916 fascia adherens(GO:0005916)
0.1 9.0 GO:0005811 lipid particle(GO:0005811)
0.1 0.3 GO:0033643 host cell part(GO:0033643)
0.1 19.6 GO:0032993 protein-DNA complex(GO:0032993)
0.1 2.2 GO:0071437 invadopodium(GO:0071437)
0.1 2.0 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 2.4 GO:0032982 myosin filament(GO:0032982)
0.1 3.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 10.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 8.2 GO:0035579 specific granule membrane(GO:0035579)
0.1 6.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 2.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 19.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 2.5 GO:0031526 brush border membrane(GO:0031526)
0.1 0.8 GO:0043194 axon initial segment(GO:0043194)
0.1 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.9 GO:0005883 neurofilament(GO:0005883)
0.1 5.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 3.1 GO:0005902 microvillus(GO:0005902)
0.1 0.8 GO:0032039 integrator complex(GO:0032039)
0.1 9.0 GO:0044306 neuron projection terminus(GO:0044306)
0.1 2.5 GO:0016592 mediator complex(GO:0016592)
0.1 5.2 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.2 GO:0046930 pore complex(GO:0046930)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 4.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 7.8 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.1 61.6 GO:0005615 extracellular space(GO:0005615)
0.1 3.7 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.4 GO:0031672 A band(GO:0031672)
0.1 5.7 GO:0043209 myelin sheath(GO:0043209)
0.0 9.0 GO:0009986 cell surface(GO:0009986)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 14.8 GO:0031226 intrinsic component of plasma membrane(GO:0031226)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 24.9 GO:0061714 folic acid receptor activity(GO:0061714)
5.6 33.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
5.1 20.5 GO:0004992 platelet activating factor receptor activity(GO:0004992)
4.9 19.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
4.9 14.7 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
4.6 54.8 GO:0008430 selenium binding(GO:0008430)
4.4 61.2 GO:0032395 MHC class II receptor activity(GO:0032395)
4.1 33.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
3.4 27.4 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
3.3 13.2 GO:0032810 sterol response element binding(GO:0032810)
3.1 9.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
3.1 9.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
2.9 8.8 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
2.8 14.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
2.8 11.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
2.7 81.7 GO:0005212 structural constituent of eye lens(GO:0005212)
2.7 10.9 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
2.6 10.3 GO:0016019 peptidoglycan receptor activity(GO:0016019)
2.6 154.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
2.6 20.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
2.5 7.6 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
2.2 15.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
2.2 6.6 GO:0031849 olfactory receptor binding(GO:0031849)
2.2 28.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
2.0 23.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.9 39.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.8 9.2 GO:0070097 delta-catenin binding(GO:0070097)
1.8 57.9 GO:0042605 peptide antigen binding(GO:0042605)
1.8 5.4 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
1.8 7.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.8 10.7 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.8 31.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.7 3.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.7 10.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
1.7 5.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.7 10.2 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
1.7 15.3 GO:0048495 Roundabout binding(GO:0048495)
1.7 5.1 GO:0005502 11-cis retinal binding(GO:0005502)
1.7 8.3 GO:0050436 microfibril binding(GO:0050436)
1.6 13.0 GO:0005534 galactose binding(GO:0005534)
1.6 4.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.6 7.8 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.5 7.6 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.5 6.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.5 4.5 GO:0019959 interleukin-8 binding(GO:0019959)
1.5 7.4 GO:0070573 metallodipeptidase activity(GO:0070573)
1.4 9.8 GO:0030911 TPR domain binding(GO:0030911)
1.4 9.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.3 14.8 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.3 5.3 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
1.3 6.6 GO:0042610 CD8 receptor binding(GO:0042610)
1.3 3.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
1.3 6.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.3 31.7 GO:0048018 receptor agonist activity(GO:0048018)
1.3 2.5 GO:0001031 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
1.3 7.6 GO:0015057 thrombin receptor activity(GO:0015057)
1.2 6.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.2 4.9 GO:0015375 glycine:sodium symporter activity(GO:0015375)
1.2 7.2 GO:0008131 primary amine oxidase activity(GO:0008131)
1.2 8.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
1.2 8.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.2 3.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.2 15.1 GO:0008199 ferric iron binding(GO:0008199)
1.1 4.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
1.1 5.6 GO:0005298 proline:sodium symporter activity(GO:0005298)
1.1 3.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
1.1 158.9 GO:0003823 antigen binding(GO:0003823)
1.1 7.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.1 2.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
1.0 14.6 GO:0045159 myosin II binding(GO:0045159)
1.0 4.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
1.0 4.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.0 14.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.0 21.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
1.0 3.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
1.0 5.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
1.0 2.9 GO:0042806 fucose binding(GO:0042806)
1.0 5.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.9 4.7 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.9 3.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.9 2.8 GO:0001601 peptide YY receptor activity(GO:0001601)
0.9 7.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.9 12.7 GO:0031419 cobalamin binding(GO:0031419)
0.9 12.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.9 2.7 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.9 6.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.9 4.4 GO:0031893 vasopressin receptor binding(GO:0031893)
0.9 5.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.8 5.0 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.8 1.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.8 3.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.8 2.4 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.8 4.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.8 2.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.8 1.6 GO:0019841 retinol binding(GO:0019841)
0.8 7.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.8 5.3 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.8 3.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.7 2.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.7 10.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.7 12.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.7 3.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.7 2.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.7 2.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.7 8.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.7 2.7 GO:0043273 CTPase activity(GO:0043273)
0.7 4.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.7 2.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.7 3.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.7 8.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.6 41.2 GO:0070412 R-SMAD binding(GO:0070412)
0.6 3.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 2.5 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.6 4.4 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.6 3.8 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.6 12.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.6 3.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.6 3.8 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.6 3.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.6 1.9 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.6 17.0 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.6 4.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.6 4.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.6 7.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.6 16.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.6 10.6 GO:0038191 neuropilin binding(GO:0038191)
0.6 2.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.6 3.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.5 2.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 6.9 GO:0016918 retinal binding(GO:0016918)
0.5 1.6 GO:0005055 laminin receptor activity(GO:0005055)
0.5 2.6 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.5 9.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.5 3.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.5 4.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.5 2.4 GO:0004447 iodide peroxidase activity(GO:0004447)
0.5 9.1 GO:0035497 cAMP response element binding(GO:0035497)
0.5 2.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.5 1.9 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.5 10.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.4 13.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4 18.6 GO:0030332 cyclin binding(GO:0030332)
0.4 5.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 10.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 25.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 13.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.4 5.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.4 6.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 8.4 GO:0008198 ferrous iron binding(GO:0008198)
0.4 7.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.4 5.8 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.4 5.8 GO:0034452 dynactin binding(GO:0034452)
0.4 2.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.4 31.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 4.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.4 1.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.4 5.8 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.4 5.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 27.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.4 3.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.4 2.6 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.4 1.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 1.1 GO:0017129 triglyceride binding(GO:0017129)
0.4 2.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.4 6.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.4 5.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.4 1.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.4 2.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.4 5.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 2.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.3 2.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 5.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 5.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.3 3.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 2.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 2.6 GO:0098821 BMP receptor activity(GO:0098821)
0.3 2.0 GO:0017040 ceramidase activity(GO:0017040)
0.3 2.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 9.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.3 1.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 4.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.3 8.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.3 3.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 1.8 GO:0030172 troponin C binding(GO:0030172)
0.3 4.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 10.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 7.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 4.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 10.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 1.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.3 1.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.3 3.9 GO:0015643 toxic substance binding(GO:0015643)
0.3 4.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 11.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.3 1.8 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.3 9.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 24.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 5.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 24.6 GO:0019905 syntaxin binding(GO:0019905)
0.2 6.4 GO:0008066 glutamate receptor activity(GO:0008066)
0.2 0.7 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.2 5.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 5.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 12.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.2 6.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 8.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 2.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 2.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 4.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 1.0 GO:0008948 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.2 2.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 0.6 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 0.8 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.2 2.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 0.7 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.2 2.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 2.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 4.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 4.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 2.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2 3.5 GO:0071837 HMG box domain binding(GO:0071837)
0.2 11.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 1.8 GO:0050700 CARD domain binding(GO:0050700)
0.2 12.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 3.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 10.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 1.4 GO:0004969 histamine receptor activity(GO:0004969)
0.2 1.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 5.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.9 GO:0019864 IgG binding(GO:0019864)
0.1 5.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 4.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 4.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 3.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.5 GO:0036310 annealing helicase activity(GO:0036310)
0.1 3.0 GO:0031489 myosin V binding(GO:0031489)
0.1 1.8 GO:0043295 glutathione binding(GO:0043295)
0.1 0.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.8 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 4.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 5.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 13.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 13.0 GO:0008201 heparin binding(GO:0008201)
0.1 63.5 GO:0003779 actin binding(GO:0003779)
0.1 3.4 GO:0019894 kinesin binding(GO:0019894)
0.1 7.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 134.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 9.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 6.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 2.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 2.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 22.0 GO:0030246 carbohydrate binding(GO:0030246)
0.1 0.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 2.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 6.6 GO:0005179 hormone activity(GO:0005179)
0.1 3.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.5 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 1.4 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 3.2 GO:0051117 ATPase binding(GO:0051117)
0.0 2.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 1.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 3.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 7.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 7.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 1.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.0 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
1.0 106.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.7 36.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.7 12.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 34.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.5 29.1 PID AURORA A PATHWAY Aurora A signaling
0.5 17.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.5 41.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.5 14.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.5 13.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.4 29.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.4 3.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.4 81.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.4 7.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 2.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 22.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.3 18.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 38.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 14.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 15.5 NABA COLLAGENS Genes encoding collagen proteins
0.3 12.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.3 8.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 5.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3 57.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 1.9 PID IL5 PATHWAY IL5-mediated signaling events
0.3 8.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 6.5 ST GA12 PATHWAY G alpha 12 Pathway
0.3 11.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.3 5.8 ST ADRENERGIC Adrenergic Pathway
0.2 5.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 6.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 14.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 12.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 17.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 8.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.2 23.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 4.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 3.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 5.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 1.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 3.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 14.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.2 PID IL27 PATHWAY IL27-mediated signaling events
0.1 4.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 6.3 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.0 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 19.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.6 PID IGF1 PATHWAY IGF1 pathway
0.1 0.8 PID INSULIN PATHWAY Insulin Pathway
0.1 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 5.1 PID E2F PATHWAY E2F transcription factor network
0.1 2.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 0.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 120.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.7 29.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.2 18.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.1 19.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.9 6.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.8 16.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.7 14.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.7 12.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.7 27.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.7 9.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.7 11.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.6 7.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.6 4.4 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.6 12.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.6 44.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.6 15.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.6 11.1 REACTOME DEFENSINS Genes involved in Defensins
0.5 23.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.5 18.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.5 43.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.5 11.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.5 26.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.5 7.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.5 9.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.5 10.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4 8.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.4 10.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 11.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.4 30.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 22.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 0.8 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.4 13.1 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.4 7.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.4 22.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.4 48.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.4 5.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 35.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 4.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.3 2.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.3 9.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.3 25.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.3 2.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 8.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.3 5.6 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.3 6.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 31.4 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.3 8.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.3 6.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.3 6.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.3 11.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3 12.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.3 4.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.3 4.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 4.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 5.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.3 4.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 15.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 9.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 44.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 14.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 11.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 10.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 5.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 1.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 5.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 3.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 4.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 5.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 6.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 4.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 5.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 8.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 4.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 4.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.7 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.1 4.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 6.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 5.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 2.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 15.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 23.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 1.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 0.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.8 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.1 2.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.3 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport