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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SOX1

Z-value: 1.06

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Transcription factors associated with SOX1

Gene Symbol Gene ID Gene Info
SOX1
ENSG00000182968.5 SOX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX1hg38_v1_chr13_+_112067143_112067160-0.045.5e-01Click!

Activity profile of SOX1 motif

Sorted Z-values of SOX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_106285898 8.60 ENST00000424768.2
ENST00000681255.1
NAMPT
nicotinamide phosphoribosyltransferase
chr17_-_15265230 5.29 ENST00000676161.1
ENST00000646419.2
ENST00000312280.9
ENST00000494511.7
ENST00000580584.3
ENST00000676221.1
PMP22
peripheral myelin protein 22
chr1_-_43172504 4.67 ENST00000431635.6
EBNA1BP2
EBNA1 binding protein 2
chr3_-_190122317 3.81 ENST00000427335.6
P3H2
prolyl 3-hydroxylase 2
chr7_+_142760398 3.58 ENST00000632998.1
PRSS2
serine protease 2
chr12_-_120325936 3.43 ENST00000549767.1
PLA2G1B
phospholipase A2 group IB
chr7_+_142749465 3.27 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
PRSS1
serine protease 1
chr13_+_53028806 2.55 ENST00000219022.3
OLFM4
olfactomedin 4
chr3_+_138608700 2.46 ENST00000360570.7
FAIM
Fas apoptotic inhibitory molecule
chr9_-_2844058 2.44 ENST00000397885.3
PUM3
pumilio RNA binding family member 3
chr3_+_138608851 2.41 ENST00000393035.6
FAIM
Fas apoptotic inhibitory molecule
chr3_+_138608575 2.28 ENST00000338446.8
FAIM
Fas apoptotic inhibitory molecule
chr8_-_109680812 2.21 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
SYBU
syntabulin
chr8_+_144078590 1.93 ENST00000525936.1
EXOSC4
exosome component 4
chr9_+_5890872 1.88 ENST00000381477.8
ENST00000381476.5
ENST00000381471.1
MLANA
melan-A
chrX_+_49171889 1.85 ENST00000376327.6
PLP2
proteolipid protein 2
chr13_-_21604145 1.82 ENST00000382374.9
ENST00000468222.2
MICU2
mitochondrial calcium uptake 2
chr14_+_61697622 1.79 ENST00000539097.2
HIF1A
hypoxia inducible factor 1 subunit alpha
chr16_-_11782552 1.78 ENST00000396516.6
ZC3H7A
zinc finger CCCH-type containing 7A
chr1_-_53940100 1.72 ENST00000371376.1
HSPB11
heat shock protein family B (small) member 11
chr3_-_58627596 1.67 ENST00000474531.5
ENST00000465970.1
FAM107A
family with sequence similarity 107 member A
chr1_+_65147657 1.64 ENST00000546702.5
AK4
adenylate kinase 4
chr20_-_50958520 1.64 ENST00000371588.10
ENST00000371584.9
ENST00000413082.1
ENST00000371582.8
DPM1
dolichyl-phosphate mannosyltransferase subunit 1, catalytic
chr14_-_60165363 1.60 ENST00000557185.6
DHRS7
dehydrogenase/reductase 7
chrX_-_32412220 1.49 ENST00000619831.5
DMD
dystrophin
chr16_+_11965234 1.44 ENST00000562385.1
TNFRSF17
TNF receptor superfamily member 17
chr12_-_10454485 1.40 ENST00000408006.7
ENST00000544822.2
ENST00000536188.5
KLRC1
killer cell lectin like receptor C1
chr12_+_9827517 1.25 ENST00000537723.5
KLRF1
killer cell lectin like receptor F1
chr10_-_72216267 1.23 ENST00000342444.8
ENST00000533958.1
ENST00000672957.1
ENST00000527593.5
ENST00000672940.1
ENST00000530461.5
ENST00000317168.11
ENST00000524829.5
ASCC1
activating signal cointegrator 1 complex subunit 1
chr8_+_144078661 1.22 ENST00000316052.6
EXOSC4
exosome component 4
chr11_+_6863057 1.21 ENST00000641461.1
OR10A2
olfactory receptor family 10 subfamily A member 2
chrX_+_129906146 1.19 ENST00000394422.8
UTP14A
UTP14A small subunit processome component
chr17_-_31297231 1.16 ENST00000247271.5
OMG
oligodendrocyte myelin glycoprotein
chr8_-_98942557 1.10 ENST00000523601.5
STK3
serine/threonine kinase 3
chr2_+_11724333 1.07 ENST00000425416.6
ENST00000396097.5
LPIN1
lipin 1
chrX_+_11111291 1.05 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
HCCS
holocytochrome c synthase
chrX_+_129906118 1.04 ENST00000425117.6
UTP14A
UTP14A small subunit processome component
chr11_-_33753394 1.03 ENST00000532057.5
ENST00000531080.5
FBXO3
F-box protein 3
chr2_-_162318129 1.02 ENST00000679938.1
IFIH1
interferon induced with helicase C domain 1
chr12_+_9827472 1.02 ENST00000617793.4
ENST00000617889.5
ENST00000354855.7
ENST00000279545.7
KLRF1
killer cell lectin like receptor F1
chr8_-_109608055 0.96 ENST00000529690.5
SYBU
syntabulin
chr1_+_84479239 0.93 ENST00000370656.5
ENST00000370654.6
RPF1
ribosome production factor 1 homolog
chr6_+_26183750 0.93 ENST00000614097.3
H2BC6
H2B clustered histone 6
chr1_-_12616762 0.88 ENST00000464917.5
DHRS3
dehydrogenase/reductase 3
chr5_-_16916400 0.87 ENST00000513882.5
MYO10
myosin X
chr10_+_93993897 0.86 ENST00000371380.8
PLCE1
phospholipase C epsilon 1
chr2_-_162318475 0.84 ENST00000648433.1
IFIH1
interferon induced with helicase C domain 1
chr2_-_162318613 0.84 ENST00000649979.2
ENST00000421365.2
IFIH1
interferon induced with helicase C domain 1
chr16_+_11965193 0.83 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chr14_-_20333306 0.81 ENST00000353689.8
ENST00000437553.6
CCNB1IP1
cyclin B1 interacting protein 1
chrX_-_63755032 0.79 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9
chr1_-_169485931 0.78 ENST00000367804.4
ENST00000646596.1
ENST00000236137.10
SLC19A2
solute carrier family 19 member 2
chr4_+_155758990 0.77 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
GUCY1B1
guanylate cyclase 1 soluble subunit beta 1
chr14_-_20333268 0.77 ENST00000358932.9
ENST00000557665.5
CCNB1IP1
cyclin B1 interacting protein 1
chr14_-_73950393 0.76 ENST00000651776.1
FAM161B
FAM161 centrosomal protein B
chr1_+_65147514 0.75 ENST00000545314.5
AK4
adenylate kinase 4
chr9_-_13165442 0.74 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr3_+_11011640 0.71 ENST00000643396.1
SLC6A1
solute carrier family 6 member 1
chr4_-_170003738 0.69 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibril associated protein 3 like
chrX_-_63755187 0.65 ENST00000635729.1
ENST00000623566.3
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9
chr11_-_47378494 0.62 ENST00000533030.1
SPI1
Spi-1 proto-oncogene
chr2_+_101998955 0.60 ENST00000393414.6
IL1R2
interleukin 1 receptor type 2
chr4_+_68815991 0.58 ENST00000265403.12
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase family 2 member B10
chr2_+_201116396 0.57 ENST00000395148.6
CFLAR
CASP8 and FADD like apoptosis regulator
chr17_-_81166160 0.57 ENST00000326724.9
AATK
apoptosis associated tyrosine kinase
chr10_-_95069489 0.54 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
CYP2C8
cytochrome P450 family 2 subfamily C member 8
chr11_+_125626229 0.51 ENST00000532449.6
ENST00000534070.5
CHEK1
checkpoint kinase 1
chr10_-_13972355 0.49 ENST00000264546.10
FRMD4A
FERM domain containing 4A
chr3_+_132597260 0.47 ENST00000249887.3
ACKR4
atypical chemokine receptor 4
chr1_-_200409976 0.45 ENST00000367352.3
ZNF281
zinc finger protein 281
chr9_-_101487120 0.43 ENST00000374848.8
PGAP4
post-GPI attachment to proteins GalNAc transferase 4
chr17_-_17281232 0.43 ENST00000417352.5
ENST00000268717.10
COPS3
COP9 signalosome subunit 3
chr12_-_64752871 0.43 ENST00000418919.6
GNS
glucosamine (N-acetyl)-6-sulfatase
chr7_-_26200734 0.40 ENST00000354667.8
ENST00000618183.5
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr10_-_90921079 0.39 ENST00000371697.4
ANKRD1
ankyrin repeat domain 1
chr2_+_209580024 0.37 ENST00000392194.5
MAP2
microtubule associated protein 2
chr1_+_70411241 0.33 ENST00000370938.8
ENST00000346806.2
CTH
cystathionine gamma-lyase
chr14_-_24609660 0.32 ENST00000557220.6
ENST00000216338.9
ENST00000382548.4
GZMH
granzyme H
chr6_+_63635792 0.32 ENST00000262043.8
ENST00000506783.5
ENST00000481385.6
ENST00000515594.5
ENST00000494284.6
PHF3
PHD finger protein 3
chr1_-_200410001 0.31 ENST00000367353.2
ZNF281
zinc finger protein 281
chr11_-_47378391 0.27 ENST00000227163.8
SPI1
Spi-1 proto-oncogene
chr19_+_54874218 0.25 ENST00000355524.8
ENST00000391726.7
FCAR
Fc fragment of IgA receptor
chr4_-_74794514 0.22 ENST00000395743.8
BTC
betacellulin
chr17_+_19282979 0.22 ENST00000395626.5
ENST00000571254.1
EPN2
epsin 2
chr1_-_200410052 0.22 ENST00000294740.3
ZNF281
zinc finger protein 281
chr11_+_103109398 0.20 ENST00000648198.1
ENST00000375735.7
ENST00000650373.2
DYNC2H1
dynein cytoplasmic 2 heavy chain 1
chr11_-_134253248 0.20 ENST00000392595.6
ENST00000352327.5
ENST00000341541.8
ENST00000392594.7
THYN1
thymocyte nuclear protein 1
chr1_-_19251509 0.19 ENST00000375199.7
ENST00000375208.7
ENST00000477853.6
EMC1
ER membrane protein complex subunit 1
chr1_+_174799895 0.18 ENST00000489615.5
RABGAP1L
RAB GTPase activating protein 1 like
chr13_+_32316063 0.17 ENST00000680887.1
BRCA2
BRCA2 DNA repair associated
chr6_+_27865308 0.17 ENST00000613174.2
H2AC16
H2A clustered histone 16
chr19_+_51761167 0.17 ENST00000340023.7
ENST00000599326.1
ENST00000598953.1
FPR2
formyl peptide receptor 2
chr1_-_144456805 0.14 ENST00000581897.6
ENST00000577412.5
NBPF15
NBPF member 15
chr19_+_17719471 0.03 ENST00000600186.5
ENST00000597735.5
ENST00000324096.9
MAP1S
microtubule associated protein 1S

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.6 3.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.5 2.7 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.5 8.6 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3 1.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.3 1.8 GO:0070101 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.3 2.4 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.3 2.4 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.3 0.8 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.3 5.3 GO:0032060 bleb assembly(GO:0032060)
0.2 0.7 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.2 1.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 1.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 2.5 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.2 3.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 0.9 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 1.6 GO:0051026 chiasma assembly(GO:0051026)
0.2 1.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 1.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.6 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 3.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.7 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.5 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 5.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 2.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 3.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 3.2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.2 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 1.0 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 2.3 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 1.2 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.5 1.8 GO:1990246 uniplex complex(GO:1990246)
0.2 3.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 3.2 GO:0097433 dense body(GO:0097433)
0.2 6.0 GO:0043218 compact myelin(GO:0043218)
0.2 5.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.5 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 2.2 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.2 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.0 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.9 GO:0032433 filopodium tip(GO:0032433)
0.0 1.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 2.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 4.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 3.8 GO:0005604 basement membrane(GO:0005604)
0.0 1.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.6 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 9.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.6 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
1.0 3.8 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.5 1.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.5 2.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 3.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 1.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 0.8 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 0.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 2.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.6 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.9 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.5 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 3.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.7 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 3.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.9 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.3 GO:0019956 chemokine binding(GO:0019956)
0.1 0.3 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157) N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.8 GO:0035035 histone acetyltransferase binding(GO:0035035) Hsp90 protein binding(GO:0051879)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 2.4 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 7.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 3.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 10.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 3.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 6.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism