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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SOX17

Z-value: 2.69

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Transcription factors associated with SOX17

Gene Symbol Gene ID Gene Info
SOX17
ENSG00000164736.6 SOX17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX17hg38_v1_chr8_+_54457927_544579430.127.7e-02Click!

Activity profile of SOX17 motif

Sorted Z-values of SOX17 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrX_+_49331616 15.64 ENST00000612958.1
GAGE13
G antigen 13
chrX_+_49341192 15.45 ENST00000621907.1
GAGE2E
G antigen 2E
chrY_+_2841864 12.49 ENST00000430575.1
RPS4Y1
ribosomal protein S4 Y-linked 1
chr2_-_89040745 11.75 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr3_-_123992046 11.21 ENST00000467907.5
ENST00000459660.5
ENST00000495093.1
ENST00000460743.5
ENST00000405845.7
ENST00000484329.1
ENST00000479867.1
ENST00000496145.5
ROPN1
rhophilin associated tail protein 1
chr19_+_6135635 10.22 ENST00000588304.5
ENST00000588722.5
ENST00000588485.6
ENST00000591403.5
ENST00000586696.5
ENST00000681525.1
ENST00000589401.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr6_-_32953017 9.43 ENST00000395305.7
ENST00000374843.9
ENST00000395303.7
ENST00000429234.1
HLA-DMA
ENSG00000248993.1
major histocompatibility complex, class II, DM alpha
novel protein
chrX_-_6535118 9.41 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
VCX3A
variable charge X-linked 3A
chrX_+_49322057 9.39 ENST00000442437.2
GAGE12J
G antigen 12J
chr3_-_123991352 9.36 ENST00000184183.8
ROPN1
rhophilin associated tail protein 1
chr2_-_89222461 9.13 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr1_-_48472166 8.72 ENST00000371847.8
ENST00000396199.7
SPATA6
spermatogenesis associated 6
chr2_-_88992903 8.71 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr2_+_90082635 8.51 ENST00000483379.1
IGKV1D-17
immunoglobulin kappa variable 1D-17
chr3_+_125969172 8.46 ENST00000514116.6
ENST00000513830.5
ROPN1B
rhophilin associated tail protein 1B
chr3_+_125969152 8.45 ENST00000251776.8
ENST00000504401.1
ROPN1B
rhophilin associated tail protein 1B
chr12_+_10929229 8.30 ENST00000381847.7
ENST00000396400.4
PRH2
proline rich protein HaeIII subfamily 2
chr3_+_125969214 7.84 ENST00000508088.1
ROPN1B
rhophilin associated tail protein 1B
chr2_-_89117844 7.84 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr6_-_49787265 7.52 ENST00000304801.6
PGK2
phosphoglycerate kinase 2
chr11_-_7674206 7.39 ENST00000533558.5
ENST00000527542.5
CYB5R2
cytochrome b5 reductase 2
chr12_-_110920710 7.35 ENST00000546404.1
MYL2
myosin light chain 2
chr16_+_10386049 7.18 ENST00000562527.5
ENST00000396559.5
ENST00000396560.6
ENST00000562102.5
ENST00000543967.5
ENST00000569939.5
ENST00000569900.5
ATF7IP2
activating transcription factor 7 interacting protein 2
chr6_-_52803807 7.11 ENST00000334575.6
GSTA1
glutathione S-transferase alpha 1
chr16_+_2817230 7.08 ENST00000005995.8
ENST00000574813.5
PRSS21
serine protease 21
chr6_+_32637419 7.04 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr8_+_132919403 6.90 ENST00000519178.5
TG
thyroglobulin
chr7_-_29146527 6.78 ENST00000265394.10
CPVL
carboxypeptidase vitellogenic like
chr7_-_29146436 6.38 ENST00000396276.7
CPVL
carboxypeptidase vitellogenic like
chr12_+_69348372 6.02 ENST00000261267.7
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr12_-_110920568 5.67 ENST00000548438.1
ENST00000228841.15
MYL2
myosin light chain 2
chr3_-_122564253 5.65 ENST00000492382.5
ENST00000682323.1
ENST00000462315.5
PARP9
poly(ADP-ribose) polymerase family member 9
chr12_+_25052634 5.59 ENST00000548766.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr19_+_47745534 5.58 ENST00000246802.10
NOP53
NOP53 ribosome biogenesis factor
chr4_+_70028452 5.57 ENST00000530128.5
ENST00000381057.3
ENST00000673563.1
HTN3
histatin 3
chr13_-_46182136 5.49 ENST00000323076.7
LCP1
lymphocyte cytosolic protein 1
chr17_-_5234801 5.49 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr12_+_25052512 5.42 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chrX_-_8171267 5.37 ENST00000317103.5
VCX2
variable charge X-linked 2
chr11_-_116837586 5.36 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
APOA1
apolipoprotein A1
chr5_-_178187364 5.34 ENST00000463439.3
GMCL2
germ cell-less 2, spermatogenesis associated
chr12_+_25052732 5.30 ENST00000547044.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr19_+_10654261 5.18 ENST00000449870.5
ILF3
interleukin enhancer binding factor 3
chr15_-_19988117 5.05 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr17_-_59964714 4.95 ENST00000589113.1
ENST00000305783.13
RNFT1
ring finger protein, transmembrane 1
chr1_+_103617427 4.88 ENST00000423678.2
ENST00000414303.7
AMY2A
amylase alpha 2A
chr1_+_174875505 4.83 ENST00000486220.5
RABGAP1L
RAB GTPase activating protein 1 like
chr2_+_90172802 4.82 ENST00000390277.3
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr6_+_32637396 4.78 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chrX_+_8464830 4.69 ENST00000453306.4
ENST00000381032.6
ENST00000444481.3
VCX3B
variable charge X-linked 3B
chr3_+_39051990 4.48 ENST00000302313.10
WDR48
WD repeat domain 48
chr6_-_39934450 4.47 ENST00000340692.10
ENST00000373195.7
ENST00000373188.6
MOCS1
molybdenum cofactor synthesis 1
chr1_-_145995713 4.44 ENST00000425134.2
TXNIP
thioredoxin interacting protein
chr14_-_106557465 4.35 ENST00000390625.3
IGHV3-49
immunoglobulin heavy variable 3-49
chr16_+_84175933 4.29 ENST00000569735.1
DNAAF1
dynein axonemal assembly factor 1
chr12_-_11310420 4.13 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
PRB4
proline rich protein BstNI subfamily 4
chr2_-_219245465 4.13 ENST00000392089.6
GLB1L
galactosidase beta 1 like
chr16_-_5065911 3.99 ENST00000472572.8
ENST00000474471.7
C16orf89
chromosome 16 open reading frame 89
chr1_+_53894181 3.93 ENST00000361921.8
ENST00000322679.10
ENST00000613679.4
ENST00000617230.2
ENST00000610607.4
ENST00000532493.5
ENST00000525202.5
ENST00000524406.5
ENST00000388876.3
DIO1
iodothyronine deiodinase 1
chr3_+_46370854 3.88 ENST00000292303.4
CCR5
C-C motif chemokine receptor 5
chr2_-_88947820 3.81 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr2_+_86441341 3.62 ENST00000312912.10
ENST00000409064.5
KDM3A
lysine demethylase 3A
chr12_+_21527017 3.54 ENST00000535033.5
SPX
spexin hormone
chr11_+_62337424 3.32 ENST00000415229.6
ENST00000301776.9
ENST00000628829.2
ENST00000534571.5
ENST00000526096.2
ASRGL1
asparaginase and isoaspartyl peptidase 1
chr2_-_229921316 3.26 ENST00000428959.5
ENST00000675423.1
TRIP12
thyroid hormone receptor interactor 12
chr9_-_113056670 3.25 ENST00000553380.1
ENST00000374227.8
ZFP37
ZFP37 zinc finger protein
chr2_-_156342348 3.22 ENST00000409572.5
NR4A2
nuclear receptor subfamily 4 group A member 2
chr1_+_172452885 3.21 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr20_+_35968566 3.21 ENST00000373973.7
ENST00000349339.5
ENST00000489667.1
ENST00000538900.1
CNBD2
cyclic nucleotide binding domain containing 2
chr16_-_15094008 3.17 ENST00000327307.11
RRN3
RRN3 homolog, RNA polymerase I transcription factor
chr6_+_142147162 3.15 ENST00000452973.6
ENST00000620996.4
ENST00000367621.1
ENST00000367630.9
VTA1
vesicle trafficking 1
chr19_+_3933059 3.14 ENST00000616156.4
ENST00000168977.6
ENST00000599576.5
NMRK2
nicotinamide riboside kinase 2
chr3_+_111542178 3.07 ENST00000283285.10
ENST00000352690.9
CD96
CD96 molecule
chr7_+_139341311 3.07 ENST00000297534.7
ENST00000541515.3
FMC1
FMC1-LUC7L2
formation of mitochondrial complex V assembly factor 1 homolog
FMC1-LUC7L2 readthrough
chr3_+_121567924 3.03 ENST00000334384.5
ARGFX
arginine-fifty homeobox
chr14_-_106811131 3.03 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr9_-_35650902 2.99 ENST00000259608.8
ENST00000618781.1
SIT1
signaling threshold regulating transmembrane adaptor 1
chr1_+_45551031 2.98 ENST00000481885.5
ENST00000471651.1
AKR1A1
aldo-keto reductase family 1 member A1
chr14_-_91946989 2.94 ENST00000556154.5
FBLN5
fibulin 5
chr1_+_13315581 2.93 ENST00000376152.2
PRAMEF15
PRAME family member 15
chr6_+_88047822 2.93 ENST00000237201.2
SPACA1
sperm acrosome associated 1
chr16_+_590056 2.89 ENST00000248139.8
ENST00000568586.5
ENST00000538492.5
RAB40C
RAB40C, member RAS oncogene family
chr6_-_42142604 2.88 ENST00000356542.5
ENST00000341865.9
C6orf132
chromosome 6 open reading frame 132
chr14_-_106235582 2.88 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr1_+_24643264 2.87 ENST00000374389.8
ENST00000323848.14
ENST00000447431.6
SRRM1
serine and arginine repetitive matrix 1
chr11_+_65027402 2.84 ENST00000377244.8
ENST00000534637.5
ENST00000524831.5
SNX15
sorting nexin 15
chr14_-_106088573 2.73 ENST00000632099.1
IGHV3-64D
immunoglobulin heavy variable 3-64D
chr1_-_173824856 2.72 ENST00000682279.1
CENPL
centromere protein L
chr3_-_58214671 2.71 ENST00000460422.1
ENST00000483681.5
DNASE1L3
deoxyribonuclease 1 like 3
chr10_+_75111476 2.69 ENST00000671730.1
SAMD8
sterile alpha motif domain containing 8
chr19_+_43716070 2.65 ENST00000244314.6
IRGC
immunity related GTPase cinema
chr4_-_185956652 2.65 ENST00000355634.9
SORBS2
sorbin and SH3 domain containing 2
chr19_+_43716095 2.61 ENST00000596627.1
IRGC
immunity related GTPase cinema
chr7_+_57450171 2.58 ENST00000420713.2
ZNF716
zinc finger protein 716
chr2_-_151971750 2.54 ENST00000636598.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr19_+_10654327 2.52 ENST00000407004.7
ENST00000589998.5
ENST00000589600.5
ILF3
interleukin enhancer binding factor 3
chr1_-_150808251 2.49 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
CTSK
cathepsin K
chr1_+_158931539 2.46 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
PYHIN1
pyrin and HIN domain family member 1
chr10_+_75111595 2.45 ENST00000671800.1
ENST00000542569.6
ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr1_-_9072252 2.38 ENST00000474145.5
SLC2A5
solute carrier family 2 member 5
chr1_+_13254212 2.38 ENST00000622421.2
PRAMEF5
PRAME family member 5
chr1_+_22007450 2.38 ENST00000400271.2
CELA3A
chymotrypsin like elastase 3A
chr11_-_85665077 2.38 ENST00000527447.2
CREBZF
CREB/ATF bZIP transcription factor
chrX_+_102247167 2.35 ENST00000625106.4
NXF2
nuclear RNA export factor 2
chr2_-_157444044 2.26 ENST00000264192.8
CYTIP
cytohesin 1 interacting protein
chr4_+_154743993 2.21 ENST00000336356.4
LRAT
lecithin retinol acyltransferase
chr19_-_58002761 2.21 ENST00000552184.1
ENST00000546715.5
ENST00000547828.5
ENST00000547121.5
ENST00000551380.6
ZNF606
zinc finger protein 606
chr1_-_13155961 2.17 ENST00000624207.1
PRAMEF26
PRAME family member 26
chr1_+_75796867 2.12 ENST00000263187.4
MSH4
mutS homolog 4
chr19_+_3933581 2.11 ENST00000593949.1
NMRK2
nicotinamide riboside kinase 2
chr6_+_125919296 2.10 ENST00000444128.2
NCOA7
nuclear receptor coactivator 7
chr16_+_31355165 2.09 ENST00000562918.5
ENST00000268296.9
ITGAX
integrin subunit alpha X
chr6_+_125919210 2.06 ENST00000438495.6
NCOA7
nuclear receptor coactivator 7
chr8_-_7452365 2.06 ENST00000458665.5
ENST00000528168.3
SPAG11B
sperm associated antigen 11B
chr16_+_33827140 2.06 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr19_-_53254841 2.04 ENST00000601828.5
ENST00000599012.5
ENST00000598513.6
ENST00000598806.5
ZNF677
zinc finger protein 677
chr11_+_60378524 2.03 ENST00000530614.5
ENST00000530027.5
ENST00000300184.8
ENST00000530234.2
ENST00000528215.1
ENST00000531787.5
MS4A7
MS4A14
membrane spanning 4-domains A7
membrane spanning 4-domains A14
chr22_+_32357867 2.01 ENST00000249007.4
RFPL3
ret finger protein like 3
chr2_+_1414382 2.00 ENST00000423320.5
ENST00000346956.7
ENST00000382198.5
TPO
thyroid peroxidase
chr3_+_73061659 2.00 ENST00000533473.1
EBLN2
endogenous Bornavirus like nucleoprotein 2
chr6_+_135851681 1.99 ENST00000308191.11
PDE7B
phosphodiesterase 7B
chr17_-_45060988 1.94 ENST00000342350.9
DCAKD
dephospho-CoA kinase domain containing
chr19_-_3626746 1.94 ENST00000429344.7
ENST00000248420.9
ENST00000221899.7
CACTIN
cactin, spliceosome C complex subunit
chr3_+_98732688 1.93 ENST00000486334.6
ENST00000394162.5
ENST00000613264.4
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr11_+_60378475 1.92 ENST00000358246.5
MS4A7
membrane spanning 4-domains A7
chr1_-_154956086 1.92 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBXIP1
PBX homeobox interacting protein 1
chr14_-_106511856 1.92 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr3_-_52454032 1.87 ENST00000232975.8
TNNC1
troponin C1, slow skeletal and cardiac type
chr2_+_43838963 1.86 ENST00000272286.4
ABCG8
ATP binding cassette subfamily G member 8
chr2_+_181457342 1.85 ENST00000397033.7
ENST00000233573.6
ITGA4
integrin subunit alpha 4
chr17_+_3420568 1.84 ENST00000574571.4
OR3A3
olfactory receptor family 3 subfamily A member 3
chr19_+_54769785 1.83 ENST00000336077.11
KIR2DL1
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
chr1_+_15617415 1.82 ENST00000480945.6
DDI2
DNA damage inducible 1 homolog 2
chr2_+_216633411 1.81 ENST00000233809.9
IGFBP2
insulin like growth factor binding protein 2
chr6_+_29301701 1.80 ENST00000641895.1
OR14J1
olfactory receptor family 14 subfamily J member 1
chr2_+_33436304 1.80 ENST00000402538.7
RASGRP3
RAS guanyl releasing protein 3
chr4_+_70197924 1.80 ENST00000514097.5
ODAM
odontogenic, ameloblast associated
chr16_+_31355215 1.77 ENST00000562522.2
ITGAX
integrin subunit alpha X
chr13_+_24764158 1.77 ENST00000255324.10
ENST00000255325.6
RNF17
ring finger protein 17
chr1_-_92483947 1.76 ENST00000370332.5
GFI1
growth factor independent 1 transcriptional repressor
chr12_-_7502730 1.73 ENST00000541972.5
CD163
CD163 molecule
chrY_-_17880220 1.73 ENST00000382867.4
CDY2B
chromodomain Y-linked 2B
chr18_+_24460630 1.71 ENST00000256906.5
HRH4
histamine receptor H4
chr18_+_54828406 1.70 ENST00000262094.10
RAB27B
RAB27B, member RAS oncogene family
chr1_-_12831410 1.69 ENST00000619922.1
PRAMEF11
PRAME family member 11
chr18_+_24460655 1.68 ENST00000426880.2
HRH4
histamine receptor H4
chr6_-_118935146 1.68 ENST00000619706.5
ENST00000316316.10
MCM9
minichromosome maintenance 9 homologous recombination repair factor
chrY_-_23694579 1.66 ENST00000343584.10
PRYP3
PTPN13 like Y-linked pseudogene 3
chr6_-_45377860 1.65 ENST00000371460.5
ENST00000371459.6
SUPT3H
SPT3 homolog, SAGA and STAGA complex component
chrY_+_24834127 1.64 ENST00000382296.4
ENST00000634662.1
DAZ4
deleted in azoospermia 4
chr4_+_139454070 1.62 ENST00000305626.6
RAB33B
RAB33B, member RAS oncogene family
chr7_-_115968302 1.60 ENST00000457268.5
TFEC
transcription factor EC
chr8_-_94208548 1.58 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
CDH17
cadherin 17
chr19_+_54630497 1.57 ENST00000396332.8
ENST00000427581.6
LILRB1
leukocyte immunoglobulin like receptor B1
chr17_+_27471999 1.54 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
KSR1
kinase suppressor of ras 1
chr7_-_77199808 1.53 ENST00000248598.6
FGL2
fibrinogen like 2
chr1_+_171248471 1.52 ENST00000402921.6
ENST00000617670.6
ENST00000367750.7
FMO1
flavin containing dimethylaniline monoxygenase 1
chr14_+_21825453 1.50 ENST00000390432.2
TRAV10
T cell receptor alpha variable 10
chr19_+_2163915 1.49 ENST00000398665.8
DOT1L
DOT1 like histone lysine methyltransferase
chr9_-_113056759 1.47 ENST00000555206.5
ZFP37
ZFP37 zinc finger protein
chr17_-_3063607 1.44 ENST00000575751.1
OR1D5
olfactory receptor family 1 subfamily D member 5
chr12_-_56360084 1.44 ENST00000314128.9
ENST00000557235.5
ENST00000651915.1
STAT2
signal transducer and activator of transcription 2
chr2_+_102418642 1.44 ENST00000264260.6
IL18RAP
interleukin 18 receptor accessory protein
chr1_-_12945416 1.43 ENST00000415464.6
PRAMEF6
PRAME family member 6
chr1_-_45339995 1.43 ENST00000488731.6
ENST00000435155.1
MUTYH
mutY DNA glycosylase
chr1_-_12886201 1.39 ENST00000235349.6
PRAMEF4
PRAME family member 4
chr19_-_44304968 1.38 ENST00000591609.1
ENST00000589799.5
ENST00000291182.9
ENST00000650576.1
ENST00000589248.5
ZNF235
zinc finger protein 235
chr3_+_122564327 1.38 ENST00000296161.9
ENST00000383661.3
DTX3L
deltex E3 ubiquitin ligase 3L
chr16_-_20697680 1.37 ENST00000520010.6
ACSM1
acyl-CoA synthetase medium chain family member 1
chr1_+_158831323 1.33 ENST00000368141.5
MNDA
myeloid cell nuclear differentiation antigen
chr3_+_98732236 1.33 ENST00000265261.10
ENST00000483910.5
ENST00000460774.5
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr6_+_83859640 1.32 ENST00000369679.4
ENST00000369681.10
CYB5R4
cytochrome b5 reductase 4
chr17_+_59220446 1.30 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr12_-_8662808 1.29 ENST00000359478.7
ENST00000396549.6
MFAP5
microfibril associated protein 5
chr6_-_142147122 1.28 ENST00000258042.2
NMBR
neuromedin B receptor
chr5_+_141208697 1.27 ENST00000624949.1
ENST00000622978.1
ENST00000239450.4
PCDHB12
protocadherin beta 12
chr5_-_16508858 1.27 ENST00000684456.1
RETREG1
reticulophagy regulator 1
chr8_-_17895487 1.26 ENST00000427924.5
ENST00000381841.4
FGL1
fibrinogen like 1
chr3_+_185586270 1.24 ENST00000296257.10
SENP2
SUMO specific peptidase 2
chr12_+_26011713 1.24 ENST00000542004.5
RASSF8
Ras association domain family member 8
chr6_-_42722590 1.21 ENST00000230381.7
PRPH2
peripherin 2
chr6_-_31777319 1.21 ENST00000375688.5
VWA7
von Willebrand factor A domain containing 7
chr5_-_10307821 1.20 ENST00000296658.4
CMBL
carboxymethylenebutenolidase homolog
chr7_+_95485934 1.20 ENST00000325885.6
ASB4
ankyrin repeat and SOCS box containing 4
chr12_-_8662703 1.18 ENST00000535336.5
MFAP5
microfibril associated protein 5
chr2_-_215138603 1.18 ENST00000272895.12
ABCA12
ATP binding cassette subfamily A member 12
chrX_-_13319952 1.17 ENST00000622204.1
ENST00000380622.5
ATXN3L
ataxin 3 like
chr1_+_86468902 1.17 ENST00000394711.2
CLCA1
chloride channel accessory 1
chr12_-_68253502 1.16 ENST00000328087.6
ENST00000538666.6
IL22
interleukin 22
chr15_-_33067884 1.16 ENST00000334528.13
FMN1
formin 1
chr14_+_39233908 1.16 ENST00000280082.4
MIA2
MIA SH3 domain ER export factor 2
chr5_+_170861990 1.14 ENST00000523189.6
RANBP17
RAN binding protein 17
chr1_+_15247267 1.14 ENST00000358897.8
ENST00000433640.7
FHAD1
forkhead associated phosphopeptide binding domain 1
chr19_+_16661121 1.13 ENST00000187762.7
ENST00000599479.1
TMEM38A
transmembrane protein 38A
chr5_-_168883333 1.10 ENST00000404867.7
SLIT3
slit guidance ligand 3
chr11_+_17295322 1.09 ENST00000458064.6
ENST00000622082.4
NUCB2
nucleobindin 2
chr10_-_27100463 1.08 ENST00000436985.7
ENST00000376087.5
ANKRD26
ankyrin repeat domain 26
chr15_-_42920638 1.06 ENST00000566931.1
ENST00000564431.5
ENST00000567274.5
ENST00000267890.11
TTBK2
tau tubulin kinase 2
chr21_-_32603237 1.03 ENST00000431599.1
CFAP298
cilia and flagella associated protein 298
chr12_+_52274610 1.02 ENST00000423955.7
KRT86
keratin 86

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.4 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.9 5.6 GO:1903004 regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
1.8 9.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.6 1.6 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
1.3 24.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
1.2 3.6 GO:0046292 formaldehyde metabolic process(GO:0046292)
1.2 13.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
1.1 5.4 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.1 3.2 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.9 6.9 GO:0015705 iodide transport(GO:0015705)
0.8 5.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.8 3.1 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.7 4.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.7 4.9 GO:0044245 polysaccharide digestion(GO:0044245)
0.6 5.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.6 3.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.6 1.9 GO:0002086 diaphragm contraction(GO:0002086)
0.6 1.9 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.6 1.9 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.6 3.5 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.6 1.8 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.6 4.5 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.5 1.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.5 1.5 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.5 2.5 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5 1.5 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.5 3.3 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.5 1.4 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.4 4.5 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.4 2.4 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.4 1.6 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.4 3.9 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4 8.7 GO:0044458 motile cilium assembly(GO:0044458)
0.4 0.8 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.4 3.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.4 51.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 10.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.4 1.1 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.3 3.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 1.2 GO:0035627 ceramide transport(GO:0035627)
0.3 1.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.3 4.8 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.3 7.1 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.3 5.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 5.9 GO:0006590 thyroid hormone generation(GO:0006590)
0.3 1.8 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.3 1.8 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 1.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 2.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 2.1 GO:0051026 chiasma assembly(GO:0051026)
0.2 0.7 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 0.9 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.2 1.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.2 4.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 1.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 1.2 GO:0016926 protein desumoylation(GO:0016926)
0.2 1.4 GO:0045007 depurination(GO:0045007)
0.2 1.9 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2 1.5 GO:0070995 NADPH oxidation(GO:0070995)
0.2 5.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 0.9 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.2 2.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 4.4 GO:0002347 response to tumor cell(GO:0002347)
0.2 7.5 GO:0030317 sperm motility(GO:0030317)
0.2 1.4 GO:0015816 glycine transport(GO:0015816)
0.2 9.2 GO:0015701 bicarbonate transport(GO:0015701)
0.2 5.6 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.9 GO:1901098 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.1 0.7 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 0.4 GO:1903383 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 0.4 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 2.6 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 1.0 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 2.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 3.0 GO:0097503 sialylation(GO:0097503)
0.1 11.8 GO:0031295 T cell costimulation(GO:0031295)
0.1 0.9 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.9 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 3.0 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.3 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 8.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.7 GO:0061709 reticulophagy(GO:0061709)
0.1 1.8 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 6.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 2.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 1.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.6 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 1.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 2.7 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.7 GO:0051601 exocyst localization(GO:0051601)
0.1 1.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 1.6 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.3 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 3.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 5.5 GO:0007127 meiosis I(GO:0007127)
0.1 6.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 9.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 2.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 3.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.6 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 6.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.0 GO:0043691 reverse cholesterol transport(GO:0043691)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.9 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 3.9 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 1.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 2.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 2.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 4.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.7 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 2.9 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166) regulation of tooth mineralization(GO:0070170)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.5 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.7 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 2.0 GO:0007586 digestion(GO:0007586)
0.0 1.1 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 1.3 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
0.0 5.2 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 1.5 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 1.1 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:0097224 sperm connecting piece(GO:0097224)
1.3 5.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.1 21.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.9 1.9 GO:1990584 cardiac Troponin complex(GO:1990584)
0.9 5.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.8 13.0 GO:0097512 cardiac myofibril(GO:0097512)
0.8 7.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.6 2.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.5 5.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.5 1.9 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.4 2.1 GO:0005713 recombination nodule(GO:0005713)
0.4 2.5 GO:0036021 endolysosome lumen(GO:0036021)
0.3 3.8 GO:0005577 fibrinogen complex(GO:0005577)
0.3 17.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 2.9 GO:0071953 elastic fiber(GO:0071953)
0.2 5.5 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.6 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 2.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 12.5 GO:0005844 polysome(GO:0005844)
0.2 0.7 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 1.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 3.5 GO:0031045 dense core granule(GO:0031045)
0.1 0.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 5.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 17.2 GO:0031514 motile cilium(GO:0031514)
0.1 2.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.6 GO:0000124 SAGA complex(GO:0000124)
0.1 2.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 3.9 GO:0008305 integrin complex(GO:0008305)
0.1 2.1 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.7 GO:0072687 meiotic spindle(GO:0072687)
0.1 5.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.7 GO:0042611 MHC protein complex(GO:0042611)
0.1 4.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 1.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.4 GO:0005827 polar microtubule(GO:0005827)
0.1 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 7.8 GO:0072562 blood microparticle(GO:0072562)
0.0 1.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 7.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 5.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 40.8 GO:0005615 extracellular space(GO:0005615)
0.0 2.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.4 GO:0035579 specific granule membrane(GO:0035579)
0.0 4.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 3.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.7 5.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.6 4.9 GO:0004556 alpha-amylase activity(GO:0004556)
1.5 9.0 GO:0003796 lysozyme activity(GO:0003796)
1.3 5.3 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.1 6.5 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
1.1 3.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.9 8.7 GO:0032027 myosin light chain binding(GO:0032027)
0.8 11.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.8 3.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.8 8.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.8 3.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.6 13.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.6 13.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.6 10.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 24.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.5 1.5 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.5 4.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.4 2.0 GO:0004447 iodide peroxidase activity(GO:0004447)
0.4 5.6 GO:0008097 5S rRNA binding(GO:0008097)
0.4 2.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.4 1.6 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.4 1.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.4 86.4 GO:0003823 antigen binding(GO:0003823)
0.4 2.2 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.4 1.4 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.4 3.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.4 3.2 GO:0004969 histamine receptor activity(GO:0004969)
0.3 1.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.3 3.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 1.5 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 4.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 0.7 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.2 7.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 5.7 GO:0070403 NAD+ binding(GO:0070403)
0.2 1.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.9 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2 1.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 1.9 GO:0031013 troponin I binding(GO:0031013)
0.2 12.5 GO:0019843 rRNA binding(GO:0019843)
0.2 0.6 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 1.8 GO:0005549 odorant binding(GO:0005549)
0.2 0.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 1.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 3.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 2.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 2.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 3.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 4.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 3.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 2.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 2.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 7.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 3.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 3.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 3.2 GO:0030552 cAMP binding(GO:0030552)
0.1 0.9 GO:0031432 titin binding(GO:0031432)
0.1 5.5 GO:0005179 hormone activity(GO:0005179)
0.1 5.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 1.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 4.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 8.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 4.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.5 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 2.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 2.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 2.1 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 5.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 2.2 PID CONE PATHWAY Visual signal transduction: Cones
0.1 5.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 4.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 4.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 6.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 9.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID MYC PATHWAY C-MYC pathway
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 3.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.6 11.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4 4.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 8.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 5.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 4.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 14.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 7.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 2.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 12.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 3.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 7.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 4.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 5.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 2.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 6.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.6 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 3.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 3.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.8 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 3.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling