Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for SOX21

Z-value: 1.01

Motif logo

logo of

Transcription factors associated with SOX21

Gene Symbol Gene ID Gene Info
SOX21
ENSG00000125285.6 SOX21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX21hg38_v1_chr13_-_94712505_947125530.283.6e-05Click!

Activity profile of SOX21 motif

Sorted Z-values of SOX21 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX21

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_155806260 7.80 ENST00000534941.2
ENST00000340171.7
C3orf33
chromosome 3 open reading frame 33
chr7_-_16421524 6.97 ENST00000407010.7
CRPPA
CDP-L-ribitol pyrophosphorylase A
chr19_+_41877267 5.82 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule
chr19_+_16197900 4.05 ENST00000429941.6
ENST00000291439.8
ENST00000444449.6
ENST00000589822.5
AP1M1
adaptor related protein complex 1 subunit mu 1
chr14_+_92121953 3.25 ENST00000298875.9
ENST00000553427.5
CPSF2
cleavage and polyadenylation specific factor 2
chr18_+_35241027 3.16 ENST00000330501.12
ENST00000601719.1
ENST00000591206.5
ENST00000261333.10
ENST00000355632.8
ENST00000585800.1
ZNF397
zinc finger protein 397
chr2_+_89851723 2.79 ENST00000429992.2
IGKV2D-40
immunoglobulin kappa variable 2D-40
chr17_+_68259164 2.78 ENST00000448504.6
ARSG
arylsulfatase G
chr1_+_2556361 2.16 ENST00000355716.5
TNFRSF14
TNF receptor superfamily member 14
chr3_-_186570308 2.12 ENST00000446782.5
TBCCD1
TBCC domain containing 1
chr5_-_56233287 2.05 ENST00000513241.2
ENST00000341048.9
ANKRD55
ankyrin repeat domain 55
chr14_-_106470788 1.99 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr9_+_102995308 1.96 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
CYLC2
cylicin 2
chr18_-_49492305 1.94 ENST00000615479.4
ENST00000583637.5
ENST00000618613.5
ENST00000615760.4
ENST00000578528.1
ENST00000578532.5
ENST00000580387.5
ENST00000579248.5
ENST00000580261.6
ENST00000581373.5
ENST00000618619.4
ENST00000617346.4
ENST00000583036.5
ENST00000332968.11
RPL17
RPL17-C18orf32
ribosomal protein L17
RPL17-C18orf32 readthrough
chr1_+_158931539 1.90 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
PYHIN1
pyrin and HIN domain family member 1
chr8_-_142879820 1.84 ENST00000377675.3
ENST00000517471.5
ENST00000292427.10
CYP11B1
cytochrome P450 family 11 subfamily B member 1
chr22_+_22720615 1.84 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr10_-_69409275 1.66 ENST00000373307.5
TACR2
tachykinin receptor 2
chr1_+_152908538 1.65 ENST00000368764.4
IVL
involucrin
chrX_+_11760087 1.61 ENST00000649271.1
MSL3
MSL complex subunit 3
chr7_-_73719629 1.57 ENST00000395155.3
ENST00000395154.7
ENST00000395156.7
ENST00000222812.8
STX1A
syntaxin 1A
chrX_-_153944621 1.57 ENST00000393700.8
RENBP
renin binding protein
chr6_+_151494007 1.51 ENST00000239374.8
CCDC170
coiled-coil domain containing 170
chr3_+_38496467 1.45 ENST00000453767.1
EXOG
exo/endonuclease G
chr15_-_79971164 1.40 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2A1
BCL2 related protein A1
chr9_-_101487120 1.34 ENST00000374848.8
PGAP4
post-GPI attachment to proteins GalNAc transferase 4
chr6_+_42563981 1.28 ENST00000372899.6
ENST00000372901.2
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr11_+_118077067 1.27 ENST00000522307.5
ENST00000523251.5
ENST00000437212.8
ENST00000522824.5
ENST00000522151.5
TMPRSS4
transmembrane serine protease 4
chr1_+_147242654 1.25 ENST00000652587.1
ENST00000361293.10
ENST00000369258.8
ENST00000369259.4
ENST00000650714.1
ENST00000639534.1
CHD1L
chromodomain helicase DNA binding protein 1 like
chr2_+_3658193 1.24 ENST00000252505.4
ALLC
allantoicase
chr4_+_74308463 1.24 ENST00000413830.6
EPGN
epithelial mitogen
chr1_+_203795614 1.18 ENST00000367210.3
ENST00000432282.5
ENST00000453771.5
ENST00000367214.5
ENST00000639812.1
ENST00000367212.7
ENST00000332127.8
ENST00000550078.2
ZC3H11A
ZBED6
zinc finger CCCH-type containing 11A
zinc finger BED-type containing 6
chr11_+_118077009 1.15 ENST00000616579.4
ENST00000534111.5
TMPRSS4
transmembrane serine protease 4
chrX_-_153944655 1.15 ENST00000369997.7
RENBP
renin binding protein
chr18_+_32190033 1.15 ENST00000269202.11
MEP1B
meprin A subunit beta
chrX_+_11760035 1.08 ENST00000482871.6
ENST00000648013.1
MSL3
MSL complex subunit 3
chr18_+_32190015 1.07 ENST00000581447.1
MEP1B
meprin A subunit beta
chr14_+_103529163 1.04 ENST00000389749.9
TRMT61A
tRNA methyltransferase 61A
chr9_-_101487091 1.03 ENST00000374847.5
PGAP4
post-GPI attachment to proteins GalNAc transferase 4
chr19_-_2783308 1.02 ENST00000677562.1
ENST00000677754.1
SGTA
small glutamine rich tetratricopeptide repeat containing alpha
chr8_-_141367276 1.02 ENST00000377741.4
GPR20
G protein-coupled receptor 20
chr17_-_44376169 1.00 ENST00000587295.5
ITGA2B
integrin subunit alpha 2b
chr3_+_36993350 1.00 ENST00000536378.5
ENST00000673899.1
ENST00000231790.8
ENST00000673715.1
ENST00000456676.6
ENST00000673673.1
MLH1
mutL homolog 1
chr12_-_949519 0.99 ENST00000397230.6
ENST00000542785.5
ENST00000544742.5
ENST00000536177.5
ENST00000541619.1
RAD52
RAD52 homolog, DNA repair protein
chr3_+_36993764 0.95 ENST00000674019.1
ENST00000458205.6
MLH1
mutL homolog 1
chr19_-_2783241 0.95 ENST00000676943.1
ENST00000589251.5
ENST00000221566.7
ENST00000676984.1
SGTA
small glutamine rich tetratricopeptide repeat containing alpha
chr12_-_949683 0.94 ENST00000358495.8
RAD52
RAD52 homolog, DNA repair protein
chr6_+_131573219 0.88 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
ARG1
arginase 1
chr20_+_62238479 0.86 ENST00000439951.6
ENST00000642957.1
ENST00000313733.9
ENST00000358053.3
ENST00000645520.1
OSBPL2
oxysterol binding protein like 2
chr3_+_38496329 0.86 ENST00000287675.10
ENST00000630638.1
ENST00000422077.6
EXOG
exo/endonuclease G
chr10_-_17201580 0.80 ENST00000525762.5
ENST00000488990.5
ENST00000377799.8
TRDMT1
tRNA aspartic acid methyltransferase 1
chr11_+_89924064 0.79 ENST00000623787.3
TRIM49D2
tripartite motif containing 49D2
chr2_+_216498831 0.78 ENST00000491306.6
ENST00000600880.5
ENST00000446558.5
RPL37A
ribosomal protein L37a
chr19_+_18571730 0.76 ENST00000596304.5
ENST00000430157.6
ENST00000596273.5
ENST00000442744.7
ENST00000595683.5
ENST00000599256.5
ENST00000595158.5
ENST00000598780.5
UBA52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr4_-_103719980 0.75 ENST00000304883.3
TACR3
tachykinin receptor 3
chr11_-_35360050 0.74 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
SLC1A2
solute carrier family 1 member 2
chr3_-_142028617 0.74 ENST00000477292.5
ENST00000478006.5
ENST00000495310.5
ENST00000486111.5
TFDP2
transcription factor Dp-2
chr8_-_19602484 0.72 ENST00000454498.6
ENST00000520003.5
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr14_+_22226711 0.69 ENST00000390463.3
TRAV36DV7
T cell receptor alpha variable 36/delta variable 7
chr1_+_67166448 0.65 ENST00000347310.10
IL23R
interleukin 23 receptor
chr1_+_151198536 0.60 ENST00000349792.9
ENST00000409426.5
ENST00000368888.9
ENST00000441902.6
ENST00000368890.8
ENST00000424999.1
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
chrX_+_3066833 0.60 ENST00000359361.2
ARSF
arylsulfatase F
chr3_-_155854375 0.54 ENST00000643144.2
ENST00000359479.7
ENST00000646424.1
SLC33A1
solute carrier family 33 member 1
chr6_+_29396555 0.54 ENST00000623183.1
OR12D2
olfactory receptor family 12 subfamily D member 2
chr22_-_40533808 0.53 ENST00000422851.1
ENST00000651694.1
ENST00000652095.2
MRTFA
myocardin related transcription factor A
chr10_-_12042771 0.51 ENST00000357604.10
UPF2
UPF2 regulator of nonsense mediated mRNA decay
chr1_+_200027702 0.49 ENST00000367362.8
NR5A2
nuclear receptor subfamily 5 group A member 2
chrX_-_101291325 0.43 ENST00000356784.2
TAF7L
TATA-box binding protein associated factor 7 like
chr12_+_101280093 0.41 ENST00000261637.5
UTP20
UTP20 small subunit processome component
chr3_+_36993798 0.40 ENST00000455445.6
ENST00000539477.6
ENST00000435176.5
ENST00000429117.5
ENST00000441265.6
MLH1
mutL homolog 1
chr12_-_10435940 0.39 ENST00000381901.5
ENST00000381902.7
ENST00000539033.1
KLRC2
ENSG00000255641.1
killer cell lectin like receptor C2
novel protein
chr1_-_169485931 0.37 ENST00000367804.4
ENST00000646596.1
ENST00000236137.10
SLC19A2
solute carrier family 19 member 2
chr1_+_200027605 0.34 ENST00000236914.7
NR5A2
nuclear receptor subfamily 5 group A member 2
chr4_+_68447453 0.32 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr14_+_21941122 0.29 ENST00000390441.2
TRAV9-2
T cell receptor alpha variable 9-2
chr20_+_44715360 0.28 ENST00000190983.5
CCN5
cellular communication network factor 5
chr12_-_89352395 0.26 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chrX_-_139642518 0.26 ENST00000370573.8
ENST00000338585.6
MCF2
MCF.2 cell line derived transforming sequence
chr3_-_36993103 0.25 ENST00000322716.8
EPM2AIP1
EPM2A interacting protein 1
chrX_+_66164210 0.24 ENST00000343002.7
ENST00000336279.9
HEPH
hephaestin
chr7_-_14903319 0.22 ENST00000403951.6
DGKB
diacylglycerol kinase beta
chr12_+_122527229 0.21 ENST00000450485.6
ENST00000333479.12
KNTC1
kinetochore associated 1
chr8_+_127409026 0.12 ENST00000465342.4
POU5F1B
POU class 5 homeobox 1B
chr1_+_207325629 0.10 ENST00000618707.2
CD55
CD55 molecule (Cromer blood group)
chr3_-_58577648 0.08 ENST00000394481.5
FAM107A
family with sequence similarity 107 member A
chr11_-_8263858 0.07 ENST00000534484.1
ENST00000335790.8
LMO1
LIM domain only 1
chr8_+_66775178 0.07 ENST00000396596.2
ENST00000521960.5
ENST00000522398.5
ENST00000522629.5
ENST00000520976.5
SGK3
serum/glucocorticoid regulated kinase family member 3
chr12_-_89352487 0.02 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chrX_-_48835553 0.02 ENST00000218230.6
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr18_+_11857440 0.00 ENST00000602628.1
GNAL
G protein subunit alpha L

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.6 2.3 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.5 3.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.5 2.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.5 2.7 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.4 2.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.4 1.2 GO:0043605 cellular amide catabolic process(GO:0043605)
0.4 1.7 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.3 1.7 GO:0035106 operant conditioning(GO:0035106)
0.3 1.6 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.3 1.9 GO:2000819 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) regulation of nucleotide-excision repair(GO:2000819)
0.3 1.3 GO:0071233 cellular response to leucine(GO:0071233)
0.2 0.7 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 0.9 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.2 0.7 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.2 4.1 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.2 1.8 GO:0035865 cellular response to potassium ion(GO:0035865)
0.2 0.8 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 0.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.4 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.5 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.4 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 8.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 1.8 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 7.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 1.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.0 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.7 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 1.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 2.2 GO:1901998 toxin transport(GO:1901998)
0.0 3.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 3.4 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 2.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.6 GO:0072661 protein targeting to plasma membrane(GO:0072661) ruffle assembly(GO:0097178)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.8 GO:0019815 B cell receptor complex(GO:0019815)
0.7 2.0 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.6 2.3 GO:0005715 late recombination nodule(GO:0005715)
0.4 1.6 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 1.0 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.3 2.7 GO:0072487 MSL complex(GO:0072487)
0.3 3.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 0.7 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 2.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 4.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.2 GO:0000346 transcription export complex(GO:0000346)
0.1 0.2 GO:1990423 RZZ complex(GO:1990423)
0.1 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 2.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.7 GO:0001533 cornified envelope(GO:0001533)
0.0 3.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 2.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.9 GO:0035580 specific granule lumen(GO:0035580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.6 1.7 GO:0016497 substance K receptor activity(GO:0016497)
0.4 0.8 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 1.0 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.3 2.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 3.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 0.7 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.2 1.3 GO:0070728 leucine binding(GO:0070728)
0.2 0.6 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2 1.0 GO:0070051 fibrinogen binding(GO:0070051)
0.2 2.3 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.2 2.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 0.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.7 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 2.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.4 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 2.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.4 GO:0051400 BH domain binding(GO:0051400)
0.1 2.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 4.6 GO:0003823 antigen binding(GO:0003823)
0.0 1.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.9 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0051184 cofactor transporter activity(GO:0051184)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.2 PID BCR 5PATHWAY BCR signaling pathway
0.1 4.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 3.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 3.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 5.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 2.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 2.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors