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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SOX4

Z-value: 3.27

Motif logo

Transcription factors associated with SOX4

Gene Symbol Gene ID Gene Info
ENSG00000124766.7 SOX4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX4hg38_v1_chr6_+_21593742_21593757-0.073.1e-01Click!

Activity profile of SOX4 motif

Sorted Z-values of SOX4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_244835616 21.08 ENST00000366528.3
ENST00000411948.7
cytochrome c oxidase assembly factor COX20
chr17_-_64390852 10.01 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr14_-_59630582 9.97 ENST00000395090.5
reticulon 1
chr8_+_79611727 9.78 ENST00000518491.1
stathmin 2
chr14_+_75280078 9.32 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr14_-_21048431 8.92 ENST00000555026.5
NDRG family member 2
chr18_-_77017042 8.88 ENST00000359645.7
ENST00000397875.7
ENST00000397869.7
ENST00000578193.5
ENST00000578873.5
ENST00000397866.8
ENST00000528160.1
ENST00000527041.1
ENST00000526111.5
ENST00000397865.9
ENST00000382582.7
myelin basic protein
chr8_+_79611036 7.98 ENST00000220876.12
ENST00000518111.5
stathmin 2
chr5_+_141359970 7.77 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr3_+_39467672 6.73 ENST00000436143.6
ENST00000441980.6
ENST00000682069.1
ENST00000311042.10
myelin associated oligodendrocyte basic protein
chr11_+_114060204 6.61 ENST00000683318.1
zinc finger and BTB domain containing 16
chr15_+_24954912 6.49 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr15_+_78438279 6.40 ENST00000560440.5
iron responsive element binding protein 2
chr13_-_110307131 6.32 ENST00000543140.6
ENST00000375820.10
collagen type IV alpha 1 chain
chr3_+_39467598 6.11 ENST00000428261.5
ENST00000420739.5
ENST00000415443.5
ENST00000447324.5
ENST00000383754.7
myelin associated oligodendrocyte basic protein
chr14_+_96039328 5.91 ENST00000553764.1
ENST00000555004.3
ENST00000556728.1
ENST00000553782.1
chromosome 14 open reading frame 132
chrX_+_12975083 5.59 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr6_-_166627244 5.46 ENST00000265678.9
ribosomal protein S6 kinase A2
chr9_+_98943705 5.38 ENST00000610452.1
collagen type XV alpha 1 chain
chr19_+_57584131 5.32 ENST00000536878.6
ENST00000597219.1
ENST00000598689.1
ENST00000597850.2
zinc finger protein interacting with K protein 1
chr2_-_1744442 5.28 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr7_-_103989649 4.94 ENST00000428762.6
reelin
chr16_+_6019585 4.83 ENST00000547372.5
RNA binding fox-1 homolog 1
chr6_+_41072939 4.83 ENST00000341376.11
ENST00000353205.5
nuclear transcription factor Y subunit alpha
chr15_+_80404320 4.77 ENST00000303329.9
ENST00000622346.4
aryl hydrocarbon receptor nuclear translocator 2
chr11_-_5254741 4.58 ENST00000444587.1
ENST00000336906.6
ENST00000642908.1
ENST00000647543.1
hemoglobin subunit gamma 2
novel protein
chrX_+_12975216 4.52 ENST00000380635.5
thymosin beta 4 X-linked
chr1_+_151060357 4.46 ENST00000368921.5
MLLT11 transcription factor 7 cofactor
chr20_-_40689228 4.31 ENST00000373313.3
MAF bZIP transcription factor B
chr4_+_77157189 4.27 ENST00000316355.10
ENST00000502280.5
cyclin G2
chr6_+_125919296 4.18 ENST00000444128.2
nuclear receptor coactivator 7
chr7_+_100101657 4.16 ENST00000421755.5
adaptor related protein complex 4 subunit mu 1
chr1_+_42463221 4.12 ENST00000654683.1
ENST00000667205.1
ENST00000655164.1
ENST00000657597.1
ENST00000667947.1
ENST00000668663.1
ENST00000660083.1
ENST00000655845.1
ENST00000671281.1
ENST00000664805.1
ENST00000654604.1
ENST00000655447.1
ENST00000661864.1
ENST00000665176.1
ENST00000670982.1
ENST00000668036.1
coiled-coil domain containing 30
chr5_+_141370236 4.06 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr10_+_11165475 3.88 ENST00000609692.5
ENST00000354897.3
CUGBP Elav-like family member 2
chr10_+_68721012 3.79 ENST00000536391.5
ENST00000630771.2
cell division cycle and apoptosis regulator 1
chr8_+_78666056 3.77 ENST00000263849.9
zinc finger C2HC-type containing 1A
chr16_+_6019016 3.75 ENST00000550418.6
RNA binding fox-1 homolog 1
chr6_+_125919210 3.65 ENST00000438495.6
nuclear receptor coactivator 7
chr7_+_100101632 3.63 ENST00000359593.9
adaptor related protein complex 4 subunit mu 1
chr5_+_141387698 3.57 ENST00000615384.1
ENST00000519479.2
protocadherin gamma subfamily B, 4
chr2_-_2324323 3.54 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr10_+_11164961 3.53 ENST00000399850.7
ENST00000417956.6
CUGBP Elav-like family member 2
chr1_-_203182805 3.52 ENST00000404436.2
chitinase 3 like 1
chr7_+_100101556 3.52 ENST00000438383.5
ENST00000429084.5
ENST00000439416.5
adaptor related protein complex 4 subunit mu 1
chr2_-_9003657 3.51 ENST00000462696.1
ENST00000305997.8
membrane bound O-acyltransferase domain containing 2
chr5_+_68290637 3.50 ENST00000336483.9
phosphoinositide-3-kinase regulatory subunit 1
chr11_-_70717994 3.40 ENST00000659264.1
SH3 and multiple ankyrin repeat domains 2
chr17_+_27294076 3.38 ENST00000581440.5
ENST00000583742.1
ENST00000579733.5
ENST00000583193.5
ENST00000581185.5
ENST00000427287.6
ENST00000262394.7
ENST00000348811.6
WD repeat and SOCS box containing 1
chr16_+_6019071 3.38 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr12_-_10098977 3.24 ENST00000315330.8
ENST00000457018.6
C-type lectin domain family 1 member A
chrX_+_52184874 3.06 ENST00000599522.7
ENST00000471932.6
MAGE family member D4
chr18_-_80247348 3.00 ENST00000470488.2
ENST00000353265.8
par-6 family cell polarity regulator gamma
chr18_+_58863580 2.97 ENST00000586085.5
ENST00000589288.5
zinc finger protein 532
chr5_-_39425187 2.85 ENST00000545653.5
DAB adaptor protein 2
chr12_-_10130241 2.82 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr15_-_72272530 2.78 ENST00000569795.6
ENST00000566844.1
poly(ADP-ribose) polymerase family member 6
chr4_+_105708772 2.74 ENST00000512828.1
ENST00000394730.7
ENST00000515279.6
ENST00000507281.5
glutathione S-transferase C-terminal domain containing
chr19_-_38229654 2.72 ENST00000412732.5
ENST00000456296.5
double PHD fingers 1
chr5_-_147056010 2.72 ENST00000394414.5
protein phosphatase 2 regulatory subunit Bbeta
chr13_-_28100556 2.69 ENST00000241453.12
fms related receptor tyrosine kinase 3
chr5_-_147055968 2.67 ENST00000336640.10
protein phosphatase 2 regulatory subunit Bbeta
chr10_+_11005301 2.62 ENST00000416382.6
ENST00000631460.1
ENST00000631816.1
CUGBP Elav-like family member 2
chr11_+_5689780 2.60 ENST00000379965.8
ENST00000454828.5
tripartite motif containing 22
chrX_+_66164340 2.59 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
hephaestin
chr1_-_243255320 2.58 ENST00000366544.5
ENST00000366543.5
centrosomal protein 170
chrX_+_66164210 2.57 ENST00000343002.7
ENST00000336279.9
hephaestin
chr4_-_185956348 2.57 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr3_+_159852933 2.56 ENST00000482804.1
schwannomin interacting protein 1
chr19_-_18606779 2.48 ENST00000684169.1
ENST00000392386.8
cytokine receptor like factor 1
chr19_+_3880647 2.47 ENST00000450849.7
ATCAY kinesin light chain interacting caytaxin
chr7_-_5529949 2.47 ENST00000642480.2
ENST00000417101.2
actin beta
chr3_-_57165332 2.42 ENST00000296318.12
interleukin 17 receptor D
chr9_+_87498491 2.40 ENST00000622514.4
death associated protein kinase 1
chr3_-_50611767 2.37 ENST00000443053.6
ENST00000348721.4
cytokine inducible SH2 containing protein
chr11_-_86955385 2.35 ENST00000531380.2
frizzled class receptor 4
chr8_+_10054269 2.28 ENST00000317173.9
ENST00000441698.6
methionine sulfoxide reductase A
chr16_+_72063226 2.28 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
haptoglobin-related protein
chr17_+_59220446 2.27 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
glycerophosphodiester phosphodiesterase domain containing 1
chr7_+_139829153 2.25 ENST00000652056.1
thromboxane A synthase 1
chr2_-_240820205 2.25 ENST00000647731.1
ENST00000648680.1
ENST00000649306.1
ENST00000648129.1
ENST00000498729.9
ENST00000320389.12
ENST00000648364.1
ENST00000647885.1
ENST00000404283.9
ENST00000649096.1
kinesin family member 1A
chr14_+_69191475 2.25 ENST00000409018.7
ENST00000409014.5
ENST00000409675.5
exonuclease 3'-5' domain containing 2
chr15_+_78438199 2.23 ENST00000258886.13
iron responsive element binding protein 2
chr7_-_38265678 2.15 ENST00000443402.6
T cell receptor gamma constant 1
chr19_-_55179390 2.14 ENST00000590851.5
synaptotagmin 5
chr21_+_37006693 2.12 ENST00000329553.3
ripply transcriptional repressor 3
chr17_+_75456618 2.09 ENST00000314256.12
ENST00000582186.5
ENST00000582455.5
ENST00000581252.5
ENST00000579208.5
transmembrane protein 94
chr12_-_10130143 2.05 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr4_+_70397931 1.99 ENST00000399575.7
opiorphin prepropeptide
chr5_+_141397942 1.98 ENST00000617380.2
ENST00000621169.1
protocadherin gamma subfamily B, 5
chr14_+_91114026 1.90 ENST00000521081.5
ENST00000520328.5
ENST00000524232.5
ENST00000522170.5
ENST00000256324.15
ENST00000519950.5
ENST00000523879.5
ENST00000521077.6
ENST00000518665.6
D-glutamate cyclase
chr5_+_102865805 1.89 ENST00000346918.7
peptidylglycine alpha-amidating monooxygenase
chr12_+_93569814 1.88 ENST00000340600.6
suppressor of cytokine signaling 2
chr21_-_31732054 1.85 ENST00000399804.5
ENST00000286835.12
SR-related CTD associated factor 4
chr21_-_31160904 1.83 ENST00000636887.1
TIAM Rac1 associated GEF 1
chr8_-_81112055 1.82 ENST00000220597.4
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr11_-_1572261 1.72 ENST00000397374.8
dual specificity phosphatase 8
chr8_+_78516329 1.69 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr16_-_15643024 1.69 ENST00000540441.6
meiosis regulator and mRNA stability factor 1
chr2_-_70768175 1.67 ENST00000355733.7
ENST00000447731.6
ENST00000430656.5
ENST00000264436.9
ENST00000413157.6
adducin 2
chr19_-_38229714 1.65 ENST00000416611.5
double PHD fingers 1
chr14_+_91114431 1.63 ENST00000428926.6
ENST00000517362.5
D-glutamate cyclase
chr12_+_32107151 1.62 ENST00000548411.5
BICD cargo adaptor 1
chr5_+_87267792 1.62 ENST00000274376.11
RAS p21 protein activator 1
chr17_+_17042433 1.62 ENST00000651222.2
myosin phosphatase Rho interacting protein
chr12_-_95217373 1.61 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FYVE, RhoGEF and PH domain containing 6
chr2_+_171687457 1.61 ENST00000397119.8
ENST00000410079.7
ENST00000438879.5
dynein cytoplasmic 1 intermediate chain 2
chr2_+_171687409 1.60 ENST00000452242.5
ENST00000340296.8
dynein cytoplasmic 1 intermediate chain 2
chr8_-_17722217 1.59 ENST00000381861.7
microtubule associated scaffold protein 1
chr14_+_69191760 1.57 ENST00000409949.5
ENST00000312994.9
ENST00000409242.5
ENST00000413191.1
exonuclease 3'-5' domain containing 2
chr10_+_6202866 1.53 ENST00000317350.8
ENST00000379785.5
ENST00000625260.2
ENST00000626882.2
ENST00000360521.7
ENST00000379775.9
ENST00000640683.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr7_+_43112593 1.51 ENST00000453890.5
ENST00000395891.7
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr1_-_243255170 1.48 ENST00000366542.6
centrosomal protein 170
chr6_+_139135063 1.45 ENST00000367658.3
hdc homolog, cell cycle regulator
chr2_+_102418642 1.42 ENST00000264260.6
interleukin 18 receptor accessory protein
chr1_+_15758768 1.42 ENST00000483633.6
ENST00000502739.5
ENST00000375766.8
ENST00000431771.6
filamin binding LIM protein 1
chr14_+_91114364 1.40 ENST00000518868.5
D-glutamate cyclase
chr1_-_25906931 1.39 ENST00000357865.6
stathmin 1
chr22_-_31292445 1.38 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr5_-_39424966 1.38 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr9_-_36400860 1.38 ENST00000377877.4
ENST00000357058.7
ENST00000350199.8
ring finger protein 38
chr5_-_111756245 1.36 ENST00000447165.6
neuronal regeneration related protein
chr14_+_91114388 1.32 ENST00000519019.5
ENST00000523816.5
ENST00000517518.5
D-glutamate cyclase
chr15_+_40844018 1.32 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr7_+_80638662 1.32 ENST00000394788.7
CD36 molecule
chr12_+_101666203 1.31 ENST00000549608.1
myosin binding protein C1
chr16_+_72054477 1.27 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chrX_-_154371210 1.26 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr1_+_100351698 1.23 ENST00000644676.1
cell division cycle 14A
chr14_+_57390544 1.23 ENST00000555166.5
ENST00000556492.6
ENST00000554703.1
N-alpha-acetyltransferase 30, NatC catalytic subunit
chr12_-_10098940 1.18 ENST00000420265.2
C-type lectin domain family 1 member A
chr5_-_88877967 1.17 ENST00000508610.5
ENST00000636294.1
myocyte enhancer factor 2C
chr14_-_70809494 1.16 ENST00000381250.8
ENST00000554752.7
ENST00000555993.6
mitogen-activated protein kinase kinase kinase 9
chr10_-_60572599 1.16 ENST00000503366.5
ankyrin 3
chr7_+_5592805 1.15 ENST00000382361.8
fascin actin-bundling protein 1
chr14_+_91114667 1.08 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
D-glutamate cyclase
chr7_+_80638510 1.07 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr14_+_32329256 1.06 ENST00000280979.9
A-kinase anchoring protein 6
chr10_-_60141004 1.06 ENST00000355288.6
ankyrin 3
chr2_+_171687672 1.03 ENST00000409197.5
ENST00000456808.5
ENST00000409317.5
ENST00000409773.5
ENST00000411953.5
ENST00000409453.5
dynein cytoplasmic 1 intermediate chain 2
chr7_+_134866831 1.00 ENST00000435928.1
caldesmon 1
chr12_-_9999176 0.97 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr5_-_41213505 0.88 ENST00000337836.10
ENST00000433294.1
complement C6
chr16_-_3880678 0.86 ENST00000262367.10
CREB binding protein
chr17_-_76570544 0.85 ENST00000640006.1
novel protein
chr2_+_32946944 0.85 ENST00000404816.7
latent transforming growth factor beta binding protein 1
chrX_-_63785149 0.85 ENST00000671741.2
ENST00000625116.3
ENST00000624355.1
Cdc42 guanine nucleotide exchange factor 9
chr12_+_53097656 0.77 ENST00000301464.4
insulin like growth factor binding protein 6
chr7_-_108003122 0.76 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
laminin subunit beta 1
chr16_+_54930827 0.76 ENST00000394636.9
iroquois homeobox 5
chr7_+_116672357 0.74 ENST00000456159.1
MET proto-oncogene, receptor tyrosine kinase
chr9_-_36401198 0.73 ENST00000377885.6
ring finger protein 38
chr8_-_42768781 0.72 ENST00000276410.7
cholinergic receptor nicotinic alpha 6 subunit
chr7_+_80638633 0.71 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chrX_-_111412162 0.69 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
doublecortin
chr5_+_140855882 0.69 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
protocadherin alpha 10
chr12_+_109477368 0.68 ENST00000434735.6
ubiquitin protein ligase E3B
chr1_+_27935022 0.67 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr5_+_141408032 0.66 ENST00000520790.1
protocadherin gamma subfamily B, 6
chr5_-_84384374 0.66 ENST00000380138.3
EGF like repeats and discoidin domains 3
chr3_-_197298558 0.64 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
discs large MAGUK scaffold protein 1
chr15_-_93089192 0.63 ENST00000329082.11
repulsive guidance molecule BMP co-receptor a
chr6_+_43298254 0.60 ENST00000372585.10
ENST00000449231.5
ENST00000372589.7
solute carrier family 22 member 7
chr1_+_147902789 0.60 ENST00000369235.2
gap junction protein alpha 8
chr10_+_100462969 0.58 ENST00000343737.6
Wnt family member 8B
chr2_+_11539833 0.57 ENST00000263834.9
growth regulating estrogen receptor binding 1
chr12_-_49187369 0.54 ENST00000547939.6
tubulin alpha 1a
chr4_+_2818155 0.49 ENST00000511747.6
SH3 domain binding protein 2
chr1_-_167914089 0.45 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
adenylate cyclase 10
chr8_-_16186270 0.44 ENST00000445506.6
macrophage scavenger receptor 1
chr4_+_101813810 0.44 ENST00000444316.2
B cell scaffold protein with ankyrin repeats 1
chr19_-_17264732 0.38 ENST00000252597.8
USH1 protein network component harmonin binding protein 1
chr22_+_20917398 0.37 ENST00000354336.8
CRK like proto-oncogene, adaptor protein
chrX_+_11760035 0.35 ENST00000482871.6
ENST00000648013.1
MSL complex subunit 3
chr4_+_2469068 0.35 ENST00000541204.5
ENST00000502316.5
ENST00000507247.5
ENST00000509258.5
ENST00000314289.13
ENST00000511859.5
ring finger protein 4
chr15_-_70097852 0.32 ENST00000559191.5
TLE family member 3, transcriptional corepressor
chr9_-_16727980 0.31 ENST00000418777.5
ENST00000468187.6
basonuclin 2
chr9_+_123033660 0.30 ENST00000616002.3
G protein-coupled receptor 21
chr7_+_134779663 0.30 ENST00000361901.6
caldesmon 1
chr15_+_50182188 0.27 ENST00000267842.10
solute carrier family 27 member 2
chr9_-_14313843 0.27 ENST00000636063.1
ENST00000380921.3
ENST00000622520.1
ENST00000380959.7
nuclear factor I B
chr15_+_90872862 0.26 ENST00000618099.4
furin, paired basic amino acid cleaving enzyme
chr7_-_100081701 0.26 ENST00000292393.9
ENST00000299667.9
ENST00000413658.6
ENST00000441298.5
ENST00000449785.5
ENST00000412947.6
zinc finger protein 3
chr7_+_16753731 0.25 ENST00000262067.5
tetraspanin 13
chr3_+_181711915 0.24 ENST00000325404.3
SRY-box transcription factor 2
chr11_-_119729158 0.24 ENST00000264025.8
nectin cell adhesion molecule 1
chr6_+_43014103 0.23 ENST00000244670.12
ENST00000326974.9
ENST00000332245.9
kelch domain containing 3
chr2_-_135837170 0.22 ENST00000264162.7
lactase
chr15_-_74202742 0.22 ENST00000395105.9
signaling receptor and transporter of retinol STRA6
chr7_+_134779625 0.20 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr11_+_4704782 0.18 ENST00000380390.6
matrix metallopeptidase 26
chr5_-_176537361 0.18 ENST00000274811.9
ring finger protein 44
chr10_-_97292625 0.17 ENST00000466484.1
ENST00000358531.9
ENST00000358308.7
Rho GTPase activating protein 19
chr19_+_48624952 0.17 ENST00000599748.5
ENST00000599029.2
sphingosine kinase 2
chr1_+_65992389 0.16 ENST00000423207.6
phosphodiesterase 4B
chr8_-_42768602 0.16 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr20_-_62367304 0.15 ENST00000252999.7
laminin subunit alpha 5
chr8_-_69833338 0.11 ENST00000524945.5
solute carrier organic anion transporter family member 5A1
chr7_-_100081758 0.11 ENST00000424697.5
zinc finger protein 3
chr1_-_167518521 0.08 ENST00000362089.10
CD247 molecule

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 17.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
2.5 10.0 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
2.2 8.7 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
1.8 8.9 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.6 4.9 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
1.6 21.1 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
1.4 4.2 GO:0035026 leading edge cell differentiation(GO:0035026)
1.3 10.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) negative regulation of interleukin-8 secretion(GO:2000483)
1.1 6.6 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
1.1 4.3 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
1.0 9.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.8 11.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.8 2.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.6 2.5 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.6 2.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 1.6 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.5 8.9 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.5 2.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 11.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.5 7.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.5 1.9 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.5 4.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.5 1.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.5 1.8 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.4 1.3 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.4 1.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.3 3.1 GO:0072564 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 2.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 3.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 1.2 GO:0030035 microspike assembly(GO:0030035)
0.3 2.3 GO:0030091 protein repair(GO:0030091)
0.2 4.6 GO:0015671 oxygen transport(GO:0015671)
0.2 9.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 5.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.9 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.2 3.5 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.2 1.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 2.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 5.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 4.9 GO:0042832 defense response to protozoan(GO:0042832)
0.2 14.0 GO:0006826 iron ion transport(GO:0006826)
0.2 1.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 1.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 0.9 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 4.5 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 0.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.2 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 3.5 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 0.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 3.8 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.3 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 2.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 3.6 GO:0048665 neuron fate specification(GO:0048665)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 2.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 3.4 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.1 1.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.3 GO:0032904 viral protein processing(GO:0019082) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 1.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 2.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 10.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 4.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.7 GO:0007143 female meiotic division(GO:0007143)
0.1 4.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 2.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 2.3 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 1.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 2.0 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.2 GO:0043585 nose morphogenesis(GO:0043585) alveolar primary septum development(GO:0061143)
0.0 4.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.9 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.0 GO:0030220 platelet formation(GO:0030220)
0.0 2.3 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 1.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.6 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.3 GO:0043586 tongue development(GO:0043586)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 4.2 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 8.9 GO:0033269 internode region of axon(GO:0033269)
1.4 11.3 GO:0000138 Golgi trans cisterna(GO:0000138)
1.2 9.3 GO:0035976 AP1 complex(GO:0035976)
1.1 11.7 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.9 3.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.8 2.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.7 4.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 6.5 GO:0005687 U4 snRNP(GO:0005687)
0.4 1.2 GO:0044393 microspike(GO:0044393)
0.4 2.1 GO:1990769 proximal neuron projection(GO:1990769)
0.4 13.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 4.6 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 0.9 GO:0043259 laminin-10 complex(GO:0043259)
0.3 1.6 GO:0045298 tubulin complex(GO:0045298)
0.3 1.3 GO:0031523 Myb complex(GO:0031523)
0.2 3.4 GO:0005883 neurofilament(GO:0005883)
0.2 1.2 GO:0060091 kinocilium(GO:0060091)
0.2 2.5 GO:0097433 dense body(GO:0097433)
0.2 4.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 1.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 5.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 28.3 GO:0030426 growth cone(GO:0030426)
0.1 14.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.8 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 10.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 2.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 7.0 GO:0016605 PML body(GO:0016605)
0.0 11.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.6 GO:0071565 nBAF complex(GO:0071565)
0.0 3.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 23.6 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 2.1 GO:0036126 sperm flagellum(GO:0036126)
0.0 2.7 GO:0044853 plasma membrane raft(GO:0044853)
0.0 3.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.6 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 1.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 4.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0030350 iron-responsive element binding(GO:0030350)
1.8 21.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.2 4.9 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
1.1 5.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.9 6.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.8 2.5 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.8 2.3 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.6 3.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.6 4.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 3.5 GO:0030492 hemoglobin binding(GO:0030492)
0.5 3.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.5 1.9 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.5 2.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.4 2.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 4.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4 2.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 3.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.4 3.5 GO:0046935 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.4 3.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 4.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 1.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.3 3.5 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.3 4.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.3 4.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 1.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 1.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 1.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 1.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 4.9 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 10.1 GO:0003785 actin monomer binding(GO:0003785)
0.2 2.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 17.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 9.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 4.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 0.9 GO:0050436 microfibril binding(GO:0050436)
0.2 11.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 9.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 2.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 2.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 6.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 2.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 3.9 GO:0030507 spectrin binding(GO:0030507)
0.1 1.4 GO:0031005 filamin binding(GO:0031005)
0.1 6.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 2.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 2.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 2.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 2.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 4.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 4.3 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.7 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 12.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 2.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 9.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 5.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 4.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 5.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 5.4 PID ATR PATHWAY ATR signaling pathway
0.1 8.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.6 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 2.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 8.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 10.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 6.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.3 9.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 4.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 4.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 1.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.2 6.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 3.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 10.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 2.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 2.1 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.2 3.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 3.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 4.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 13.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 2.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 4.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins