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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SOX5

Z-value: 3.50

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Transcription factors associated with SOX5

Gene Symbol Gene ID Gene Info
ENSG00000134532.19 SOX5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX5hg38_v1_chr12_-_23584600_23584613,
hg38_v1_chr12_-_23951020_23951037
0.426.3e-11Click!

Activity profile of SOX5 motif

Sorted Z-values of SOX5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_-_10549694 11.73 ENST00000622564.4
myosin heavy chain 2
chr7_-_112206380 11.17 ENST00000437633.6
ENST00000428084.6
dedicator of cytokinesis 4
chr18_+_24014733 10.14 ENST00000317571.8
tetratricopeptide repeat domain 39C
chr12_-_6124662 9.87 ENST00000261405.10
von Willebrand factor
chr14_-_23435652 9.67 ENST00000355349.4
myosin heavy chain 7
chr12_-_16606102 9.22 ENST00000537304.6
LIM domain only 3
chr17_-_10549612 9.14 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr12_-_16605939 9.02 ENST00000541295.5
ENST00000535535.5
LIM domain only 3
chr1_-_182391363 8.42 ENST00000417584.6
glutamate-ammonia ligase
chr17_-_10549652 8.18 ENST00000245503.10
myosin heavy chain 2
chr3_-_18424533 7.79 ENST00000417717.6
SATB homeobox 1
chr1_-_156248084 7.53 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
progestin and adipoQ receptor family member 6
chr10_+_68721207 7.51 ENST00000538031.5
ENST00000543719.5
ENST00000539539.5
ENST00000265872.11
ENST00000543225.5
ENST00000536012.5
ENST00000494903.2
cell division cycle and apoptosis regulator 1
chr6_+_125919296 7.43 ENST00000444128.2
nuclear receptor coactivator 7
chr1_-_156248013 7.41 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr11_+_131911396 7.30 ENST00000425719.6
ENST00000374784.5
neurotrimin
chr1_-_156248038 7.09 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr10_+_68721012 6.99 ENST00000536391.5
ENST00000630771.2
cell division cycle and apoptosis regulator 1
chr10_+_119818699 6.86 ENST00000650409.1
inositol polyphosphate-5-phosphatase F
chr6_+_125919210 6.83 ENST00000438495.6
nuclear receptor coactivator 7
chrX_-_13817027 6.75 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr12_-_110920710 6.73 ENST00000546404.1
myosin light chain 2
chr8_-_33567118 6.68 ENST00000256257.2
ring finger protein 122
chr6_-_99425269 6.60 ENST00000647811.1
ENST00000481229.2
ENST00000369239.10
ENST00000681611.1
ENST00000681615.1
ENST00000438806.5
PNN interacting serine and arginine rich protein
chr12_-_110920568 6.43 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr9_-_127950716 6.38 ENST00000373084.8
family with sequence similarity 102 member A
chr12_+_53050014 6.19 ENST00000314250.11
tensin 2
chr15_+_83447328 6.16 ENST00000427482.7
SH3 domain containing GRB2 like 3, endophilin A3
chr15_+_83447411 6.07 ENST00000324537.5
SH3 domain containing GRB2 like 3, endophilin A3
chr16_-_11281322 6.01 ENST00000312511.4
protamine 1
chr3_+_189789672 5.93 ENST00000434928.5
tumor protein p63
chr5_-_147081428 5.92 ENST00000394413.7
protein phosphatase 2 regulatory subunit Bbeta
chrX_-_50814095 5.89 ENST00000376020.8
shroom family member 4
chrX_-_50814302 5.77 ENST00000289292.11
shroom family member 4
chr16_+_31074390 5.71 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
zinc finger protein 646
chr17_-_39607876 5.69 ENST00000302584.5
neuronal differentiation 2
chrY_+_12904102 5.64 ENST00000360160.8
ENST00000454054.5
DEAD-box helicase 3 Y-linked
chr3_-_115071333 5.64 ENST00000462705.5
zinc finger and BTB domain containing 20
chr12_+_53050179 5.64 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
tensin 2
chrX_+_136169624 5.42 ENST00000394153.6
four and a half LIM domains 1
chr14_-_91947654 5.32 ENST00000342058.9
fibulin 5
chr10_-_60389833 5.27 ENST00000280772.7
ankyrin 3
chr16_-_31074193 5.25 ENST00000300849.5
zinc finger protein 668
chr2_-_208124514 5.04 ENST00000264376.5
crystallin gamma D
chr11_-_134412234 5.00 ENST00000312527.9
beta-1,3-glucuronyltransferase 1
chr20_+_17227020 4.97 ENST00000262545.7
ENST00000536609.1
proprotein convertase subtilisin/kexin type 2
chr3_+_115623502 4.91 ENST00000305124.11
ENST00000393780.3
growth associated protein 43
chr3_-_123620571 4.89 ENST00000583087.5
myosin light chain kinase
chr4_+_164754116 4.88 ENST00000507311.1
small integral membrane protein 31
chr8_+_84183534 4.85 ENST00000518566.5
RALY RNA binding protein like
chr7_-_31340678 4.75 ENST00000297142.4
neuronal differentiation 6
chr3_-_114624193 4.71 ENST00000481632.5
zinc finger and BTB domain containing 20
chrX_+_136169833 4.68 ENST00000628032.2
four and a half LIM domains 1
chr2_+_26848093 4.65 ENST00000288699.11
dihydropyrimidinase like 5
chr15_-_34318761 4.61 ENST00000290209.9
solute carrier family 12 member 6
chr14_+_61187544 4.59 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chr18_+_33578213 4.56 ENST00000681521.1
ENST00000269197.12
ASXL transcriptional regulator 3
chr6_-_42142604 4.51 ENST00000356542.5
ENST00000341865.9
chromosome 6 open reading frame 132
chr11_+_126355634 4.50 ENST00000227495.10
ENST00000676545.1
ENST00000678865.1
ENST00000444328.7
ENST00000677503.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr1_+_28914614 4.47 ENST00000645184.1
erythrocyte membrane protein band 4.1
chr3_-_123620496 4.44 ENST00000578202.1
myosin light chain kinase
chr2_-_159616442 4.41 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
bromodomain adjacent to zinc finger domain 2B
chr14_-_91947383 4.40 ENST00000267620.14
fibulin 5
chr14_-_102509713 4.30 ENST00000286918.9
ankyrin repeat domain 9
chr12_+_49367490 4.29 ENST00000551540.5
ENST00000548777.5
ENST00000547865.5
ENST00000552171.1
spermatogenesis associated serine rich 2
chr9_-_127980976 4.29 ENST00000373095.6
family with sequence similarity 102 member A
chr8_+_84183262 4.26 ENST00000522455.5
ENST00000521695.5
ENST00000521268.6
RALY RNA binding protein like
chr3_+_181711915 4.23 ENST00000325404.3
SRY-box transcription factor 2
chr5_-_147081462 4.21 ENST00000508267.5
ENST00000504198.5
protein phosphatase 2 regulatory subunit Bbeta
chr20_-_3781440 4.04 ENST00000379756.3
sperm flagellar 1
chrX_+_136169891 3.98 ENST00000449474.5
four and a half LIM domains 1
chr18_-_55510753 3.97 ENST00000543082.5
transcription factor 4
chr4_-_86360010 3.95 ENST00000641911.1
ENST00000641072.1
ENST00000359221.8
ENST00000640490.1
mitogen-activated protein kinase 10
chr10_+_93758063 3.91 ENST00000627699.1
ENST00000371413.4
leucine rich glioma inactivated 1
chr17_+_38705482 3.89 ENST00000620609.4
MLLT6, PHD finger containing
chr11_+_46380932 3.87 ENST00000441869.5
midkine
chr12_-_102480552 3.82 ENST00000337514.11
ENST00000307046.8
insulin like growth factor 1
chr14_-_72894091 3.74 ENST00000556509.6
double PHD fingers 3
chr10_-_114684612 3.62 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr4_+_20251896 3.57 ENST00000504154.6
slit guidance ligand 2
chr1_+_150364136 3.55 ENST00000369068.5
regulation of nuclear pre-mRNA domain containing 2
chr1_+_8945858 3.50 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
carbonic anhydrase 6
chr4_+_113049479 3.49 ENST00000671727.1
ENST00000671762.1
ENST00000672366.1
ENST00000672502.1
ENST00000672045.1
ENST00000672251.1
ENST00000672854.1
ankyrin 2
chr14_+_22508602 3.47 ENST00000390504.1
T cell receptor alpha joining 33
chrX_+_136169664 3.44 ENST00000456445.5
four and a half LIM domains 1
chr2_-_156342348 3.44 ENST00000409572.5
nuclear receptor subfamily 4 group A member 2
chrX_-_17860707 3.36 ENST00000360011.5
retinoic acid induced 2
chr12_-_102478539 3.29 ENST00000424202.6
insulin like growth factor 1
chr18_+_58864866 3.26 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
zinc finger protein 532
chr12_-_52321395 3.22 ENST00000293670.3
keratin 83
chr4_-_2262082 3.22 ENST00000337190.7
MAX dimerization protein 4
chr9_-_35684766 3.21 ENST00000644325.1
tropomyosin 2
chr1_+_156619406 3.15 ENST00000255039.6
ENST00000456112.1
hyaluronan and proteoglycan link protein 2
chr19_-_50969567 3.15 ENST00000310157.7
kallikrein related peptidase 6
chr11_+_112961402 3.14 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
neural cell adhesion molecule 1
chr2_+_165572329 3.13 ENST00000342316.8
cysteine and serine rich nuclear protein 3
chr11_-_115504389 3.12 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr16_-_1782526 3.12 ENST00000566339.6
splA/ryanodine receptor domain and SOCS box containing 3
chr21_+_17513003 3.12 ENST00000284878.12
ENST00000400166.5
CXADR Ig-like cell adhesion molecule
chr17_-_43833137 3.09 ENST00000398389.9
membrane palmitoylated protein 3
chr14_+_36657560 3.02 ENST00000402703.6
paired box 9
chr1_-_151146643 3.01 ENST00000613223.1
semaphorin 6C
chr17_+_35121609 3.00 ENST00000158009.6
fibronectin type III domain containing 8
chr10_+_61901678 2.95 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr22_+_43412008 2.92 ENST00000334209.9
ENST00000443721.2
metallophosphoesterase domain containing 1
chr1_-_226739271 2.90 ENST00000429204.6
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr11_+_112961480 2.90 ENST00000621850.4
neural cell adhesion molecule 1
chr10_-_11611754 2.88 ENST00000609104.5
USP6 N-terminal like
chr2_-_2331336 2.84 ENST00000648933.1
ENST00000644820.1
myelin transcription factor 1 like
chr4_-_86360039 2.80 ENST00000515650.2
ENST00000641724.1
ENST00000641607.1
ENST00000641324.1
ENST00000641903.1
ENST00000395157.9
ENST00000641823.1
ENST00000641873.1
ENST00000641102.1
ENST00000641462.2
ENST00000641217.1
ENST00000642006.1
ENST00000641020.1
ENST00000641110.1
ENST00000639175.1
ENST00000641485.1
ENST00000641864.1
ENST00000641954.1
ENST00000641647.1
ENST00000641459.1
ENST00000641762.1
ENST00000641777.1
ENST00000641208.1
ENST00000642015.1
ENST00000641493.1
ENST00000642032.1
ENST00000641010.1
ENST00000641287.1
ENST00000641943.1
ENST00000642103.1
ENST00000641047.1
ENST00000641166.1
ENST00000641207.1
mitogen-activated protein kinase 10
chr10_-_60572599 2.78 ENST00000503366.5
ankyrin 3
chr4_+_113049616 2.78 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr4_-_185810894 2.76 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chr4_+_41612892 2.73 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr1_-_151146611 2.73 ENST00000341697.7
ENST00000368914.8
semaphorin 6C
chr19_+_7516081 2.66 ENST00000597229.2
zinc finger protein 358
chr15_-_85794902 2.66 ENST00000337975.6
kelch like family member 25
chr9_-_37465402 2.63 ENST00000307750.5
zinc finger and BTB domain containing 5
chr19_+_12838437 2.62 ENST00000251472.9
microtubule associated serine/threonine kinase 1
chr12_-_102480638 2.61 ENST00000392904.5
insulin like growth factor 1
chr11_-_7020235 2.61 ENST00000536068.5
ENST00000278314.5
zinc finger protein 214
chr17_-_41586887 2.54 ENST00000167586.7
keratin 14
chr5_-_168883333 2.54 ENST00000404867.7
slit guidance ligand 3
chr2_-_2326378 2.54 ENST00000647618.1
myelin transcription factor 1 like
chr17_-_64390852 2.49 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr12_-_8662808 2.46 ENST00000359478.7
ENST00000396549.6
microfibril associated protein 5
chr16_+_2033264 2.45 ENST00000565855.5
ENST00000566198.1
SLC9A3 regulator 2
chr10_+_93757831 2.44 ENST00000629035.2
leucine rich glioma inactivated 1
chr6_+_122399621 2.41 ENST00000368455.9
heat shock transcription factor 2
chr18_+_44680875 2.38 ENST00000649279.2
ENST00000677699.1
SET binding protein 1
chr4_+_25655822 2.36 ENST00000504570.5
ENST00000382051.8
solute carrier family 34 member 2
chr3_+_14947680 2.35 ENST00000435454.5
ENST00000323373.10
nuclear receptor subfamily 2 group C member 2
chr1_+_11691688 2.31 ENST00000294485.6
dorsal inhibitory axon guidance protein
chr3_-_99876104 2.31 ENST00000471562.1
ENST00000495625.2
filamin A interacting protein 1 like
chr2_-_2331225 2.30 ENST00000648627.1
ENST00000649663.1
ENST00000650560.1
ENST00000428368.7
ENST00000648316.1
ENST00000648665.1
ENST00000649313.1
ENST00000399161.7
ENST00000647738.2
myelin transcription factor 1 like
chr1_+_50108856 2.29 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr2_-_187448244 2.29 ENST00000392370.8
ENST00000410068.5
ENST00000447403.5
ENST00000410102.5
calcitonin receptor like receptor
chrX_-_107716401 2.27 ENST00000486554.1
ENST00000372390.8
TSC22 domain family member 3
chr11_-_82997477 2.25 ENST00000534301.5
RAB30, member RAS oncogene family
chr9_-_120714457 2.21 ENST00000373930.4
multiple EGF like domains 9
chrX_+_108045050 2.21 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr2_-_25982471 2.20 ENST00000264712.8
kinesin family member 3C
chr11_+_112961247 2.18 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
neural cell adhesion molecule 1
chr8_-_71362054 2.16 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr18_-_55322215 2.13 ENST00000457482.7
transcription factor 4
chr14_-_91946989 2.12 ENST00000556154.5
fibulin 5
chr10_+_35127295 2.11 ENST00000489321.5
ENST00000427847.6
ENST00000374728.7
ENST00000345491.7
ENST00000487132.5
cAMP responsive element modulator
chr1_+_209583706 2.10 ENST00000361322.3
ENST00000651530.1
ENST00000009105.5
ENST00000423146.5
calcium/calmodulin dependent protein kinase IG
chr17_-_16569184 2.09 ENST00000448349.2
ENST00000395825.4
zinc finger protein 287
chrX_+_108439779 2.08 ENST00000328300.11
collagen type IV alpha 5 chain
chr5_+_68292562 2.08 ENST00000523872.1
phosphoinositide-3-kinase regulatory subunit 1
chr10_+_48306698 2.06 ENST00000374179.8
mitogen-activated protein kinase 8
chr2_-_70248598 2.04 ENST00000445587.5
ENST00000433529.7
ENST00000415783.6
TIA1 cytotoxic granule associated RNA binding protein
chr12_+_51912329 2.04 ENST00000547400.5
ENST00000550683.5
ENST00000419526.6
activin A receptor like type 1
chrX_+_108044967 1.99 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr3_-_46863435 1.98 ENST00000395869.5
ENST00000653454.1
ENST00000292327.6
myosin light chain 3
chr4_-_67883987 1.95 ENST00000283916.11
transmembrane serine protease 11D
chr4_-_86360071 1.94 ENST00000641677.1
ENST00000639234.1
ENST00000641553.1
ENST00000641826.1
ENST00000641537.1
ENST00000395169.9
ENST00000641408.1
ENST00000638225.1
ENST00000641052.1
mitogen-activated protein kinase 10
chr11_+_33258304 1.94 ENST00000531504.5
ENST00000456517.2
homeodomain interacting protein kinase 3
chr10_+_35127023 1.93 ENST00000429130.7
ENST00000469949.6
ENST00000460270.5
cAMP responsive element modulator
chr10_+_93757857 1.89 ENST00000478763.2
ENST00000371418.9
ENST00000630184.2
ENST00000630047.2
ENST00000637689.1
leucine rich glioma inactivated 1
chr1_-_167914089 1.86 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
adenylate cyclase 10
chr10_+_48306639 1.83 ENST00000395611.7
ENST00000432379.5
ENST00000374189.5
mitogen-activated protein kinase 8
chr22_-_40463411 1.82 ENST00000402630.5
ENST00000407029.7
myocardin related transcription factor A
chr1_+_164559739 1.78 ENST00000627490.2
PBX homeobox 1
chr8_+_102551583 1.75 ENST00000285402.4
outer dense fiber of sperm tails 1
chr7_+_112206683 1.75 ENST00000361822.8
ENST00000421043.5
ENST00000425229.5
ENST00000450657.1
zinc finger protein 277
chr8_-_71361860 1.72 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chrX_-_53684119 1.72 ENST00000342160.7
ENST00000446750.1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
chr6_+_122399536 1.71 ENST00000452194.5
heat shock transcription factor 2
chr18_-_55321986 1.71 ENST00000570287.6
transcription factor 4
chr5_-_135535955 1.69 ENST00000314744.6
neurogenin 1
chr3_+_89107649 1.68 ENST00000452448.6
ENST00000494014.1
EPH receptor A3
chr14_+_74348440 1.68 ENST00000256362.5
vertebrae development associated
chr11_-_35419213 1.66 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
solute carrier family 1 member 2
chrX_+_108439866 1.63 ENST00000361603.7
collagen type IV alpha 5 chain
chr12_-_51083582 1.62 ENST00000548206.1
ENST00000546935.5
ENST00000228515.6
ENST00000548981.5
cysteine and serine rich nuclear protein 2
chr3_+_171843337 1.61 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr9_-_69672341 1.60 ENST00000265381.7
amyloid beta precursor protein binding family A member 1
chr3_+_41194741 1.60 ENST00000643541.1
ENST00000426215.5
ENST00000645210.1
ENST00000646381.1
ENST00000405570.6
ENST00000642248.1
ENST00000433400.6
catenin beta 1
chr6_+_50818701 1.59 ENST00000344788.7
transcription factor AP-2 beta
chr20_-_21397513 1.58 ENST00000351817.5
NK2 homeobox 4
chr17_+_32487686 1.56 ENST00000584792.5
cyclin dependent kinase 5 regulatory subunit 1
chr12_+_77830886 1.55 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr4_+_39406917 1.54 ENST00000257408.5
klotho beta
chr11_+_128694052 1.53 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_46381194 1.53 ENST00000533952.5
midkine
chr4_+_87832917 1.52 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr3_-_52452828 1.51 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chrX_+_70444827 1.51 ENST00000374360.8
discs large MAGUK scaffold protein 3
chr1_-_193186599 1.51 ENST00000367434.5
beta-1,3-galactosyltransferase 2
chr3_+_124033356 1.51 ENST00000682506.1
kalirin RhoGEF kinase
chrX_-_112840815 1.51 ENST00000304758.5
ENST00000371959.9
angiomotin
chr3_-_129688691 1.50 ENST00000432054.6
transmembrane and coiled-coil domain family 1
chr9_-_122227525 1.46 ENST00000373755.6
ENST00000373754.6
LIM homeobox 6
chr8_-_40897814 1.44 ENST00000297737.11
ENST00000315769.11
zinc finger matrin-type 4
chr2_-_70248454 1.42 ENST00000416149.6
ENST00000282574.8
TIA1 cytotoxic granule associated RNA binding protein
chr2_+_33436304 1.41 ENST00000402538.7
RAS guanyl releasing protein 3
chr4_-_7939789 1.39 ENST00000420658.6
ENST00000358461.6
actin filament associated protein 1
chr3_-_99876193 1.37 ENST00000383694.3
filamin A interacting protein 1 like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
2.4 9.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
2.2 11.2 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
2.1 10.6 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
2.1 8.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
2.0 8.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.9 29.0 GO:0001778 plasma membrane repair(GO:0001778)
1.7 6.9 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
1.7 6.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.6 9.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.4 5.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.3 3.9 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
1.2 6.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
1.2 13.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
1.1 3.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.1 3.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
1.0 3.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
1.0 5.0 GO:0030070 insulin processing(GO:0030070)
1.0 11.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.9 6.5 GO:0030421 defecation(GO:0030421)
0.9 4.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.8 2.5 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.8 14.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.7 2.1 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.7 6.8 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.7 8.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 4.6 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.6 6.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.6 2.5 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.6 1.8 GO:0097272 ammonia homeostasis(GO:0097272)
0.5 4.9 GO:0016198 axon choice point recognition(GO:0016198)
0.5 1.6 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.5 7.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5 1.5 GO:0002086 diaphragm contraction(GO:0002086)
0.4 3.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.4 3.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 10.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.4 2.9 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.4 11.8 GO:0014850 response to muscle activity(GO:0014850)
0.4 1.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.4 2.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.3 2.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 6.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 1.6 GO:1904793 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.3 2.3 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 1.7 GO:0021650 thorax and anterior abdomen determination(GO:0007356) vestibulocochlear nerve formation(GO:0021650)
0.3 4.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 4.2 GO:0021781 glial cell fate commitment(GO:0021781)
0.2 3.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 17.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.2 7.7 GO:0048665 neuron fate specification(GO:0048665)
0.2 2.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 2.9 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 1.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2 2.0 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.2 10.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 1.3 GO:0007296 vitellogenesis(GO:0007296)
0.2 3.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 4.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 5.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 0.8 GO:0010157 response to chlorate(GO:0010157)
0.2 3.1 GO:0016540 protein autoprocessing(GO:0016540)
0.2 1.1 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
0.2 2.3 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 1.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.5 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.2 6.0 GO:0030261 chromosome condensation(GO:0030261)
0.2 4.3 GO:0021542 dentate gyrus development(GO:0021542)
0.2 0.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 4.5 GO:0097503 sialylation(GO:0097503)
0.1 0.7 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 0.7 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 1.6 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 2.1 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 5.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 4.1 GO:0008038 neuron recognition(GO:0008038)
0.1 4.3 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 2.2 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 5.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.7 GO:0032196 transposition(GO:0032196)
0.1 0.3 GO:0051036 regulation of endosome size(GO:0051036)
0.1 1.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.9 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 1.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.9 GO:0035855 megakaryocyte development(GO:0035855)
0.1 2.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.8 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 2.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 1.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.3 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 6.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 3.2 GO:0097435 fibril organization(GO:0097435)
0.1 2.9 GO:0060612 adipose tissue development(GO:0060612)
0.1 8.2 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.0 GO:0045109 intermediate filament organization(GO:0045109)
0.1 5.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 1.6 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.1 18.6 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 1.7 GO:2000772 regulation of cellular senescence(GO:2000772)
0.1 2.7 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.1 0.3 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 3.2 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 2.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 1.5 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 10.6 GO:0050890 cognition(GO:0050890)
0.0 3.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.5 GO:0046710 GDP metabolic process(GO:0046710)
0.0 1.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 6.0 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 9.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.7 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 2.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.6 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 2.4 GO:0007030 Golgi organization(GO:0007030)
0.0 2.1 GO:0070268 cornification(GO:0070268)
0.0 4.5 GO:0007601 visual perception(GO:0007601)
0.0 1.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 1.2 GO:0007631 feeding behavior(GO:0007631)
0.0 1.3 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 29.0 GO:0005826 actomyosin contractile ring(GO:0005826)
1.3 11.9 GO:0071953 elastic fiber(GO:0071953)
1.2 9.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.8 13.2 GO:0097512 cardiac myofibril(GO:0097512)
0.8 4.9 GO:0032584 growth cone membrane(GO:0032584)
0.8 1.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.6 14.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.6 7.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.5 4.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.5 2.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.5 23.3 GO:0016460 myosin II complex(GO:0016460)
0.5 3.5 GO:0097165 nuclear stress granule(GO:0097165)
0.3 6.0 GO:0000786 nucleosome(GO:0000786)
0.3 1.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 8.4 GO:0097386 glial cell projection(GO:0097386)
0.3 1.6 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.3 11.2 GO:0032420 stereocilium(GO:0032420)
0.3 10.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 6.3 GO:0031430 M band(GO:0031430)
0.2 1.7 GO:0001520 outer dense fiber(GO:0001520)
0.2 6.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 3.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 9.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 5.8 GO:0045095 keratin filament(GO:0045095)
0.1 18.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 3.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 4.1 GO:0030673 axolemma(GO:0030673)
0.1 15.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.8 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 2.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.4 GO:0045178 basal part of cell(GO:0045178)
0.0 3.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 2.2 GO:0097542 ciliary tip(GO:0097542)
0.0 6.6 GO:0043204 perikaryon(GO:0043204)
0.0 4.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 8.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 3.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242) mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 4.0 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.3 GO:0005844 polysome(GO:0005844)
0.0 2.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.8 GO:0030018 Z disc(GO:0030018)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 1.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 2.5 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.1 8.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.2 5.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.1 4.5 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
1.0 3.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.9 38.1 GO:0000146 microfilament motor activity(GO:0000146)
0.9 6.9 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.8 8.7 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.8 4.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.8 6.1 GO:0048495 Roundabout binding(GO:0048495)
0.7 15.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.6 2.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.5 1.6 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.5 6.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.5 2.5 GO:1990254 keratin filament binding(GO:1990254)
0.5 3.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.4 3.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.4 9.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 4.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.4 3.1 GO:0071253 connexin binding(GO:0071253)
0.4 28.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.4 1.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 20.8 GO:0030507 spectrin binding(GO:0030507)
0.4 5.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 2.8 GO:0098821 BMP receptor activity(GO:0098821)
0.3 1.7 GO:0004803 transposase activity(GO:0004803)
0.3 4.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 1.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 9.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 4.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 2.3 GO:0043426 MRF binding(GO:0043426)
0.3 1.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 2.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 12.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 2.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2 27.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.2 0.6 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2 2.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 0.8 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 3.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 2.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 5.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.8 GO:0070411 I-SMAD binding(GO:0070411)
0.2 1.5 GO:0031013 troponin I binding(GO:0031013)
0.1 3.8 GO:0035198 miRNA binding(GO:0035198)
0.1 11.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 2.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 5.1 GO:0070888 E-box binding(GO:0070888)
0.1 10.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.1 8.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 16.2 GO:0044325 ion channel binding(GO:0044325)
0.1 5.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 3.2 GO:0008143 poly(A) binding(GO:0008143)
0.1 12.2 GO:0005178 integrin binding(GO:0005178)
0.1 8.2 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 11.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 3.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 2.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 5.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 6.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 3.2 GO:0008201 heparin binding(GO:0008201)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 4.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 7.5 GO:0008289 lipid binding(GO:0008289)
0.0 2.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.7 38.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 13.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 4.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 43.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 11.4 PID IGF1 PATHWAY IGF1 pathway
0.2 4.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 24.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 9.8 PID FGF PATHWAY FGF signaling pathway
0.1 6.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 6.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 9.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 10.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 2.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 3.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 3.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 7.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 9.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.1 PID BMP PATHWAY BMP receptor signaling
0.1 3.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.6 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 7.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 12.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3 19.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 8.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 6.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 8.2 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.2 5.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 2.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 8.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 12.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 9.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 5.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 9.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 8.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 2.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.2 REACTOME KINESINS Genes involved in Kinesins
0.1 9.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 9.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 5.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 3.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events