ISMARA results: SOX6

Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation

Downloads

Results for SOX6

Z-value: 1.23

Motif logo

Transcription factors associated with SOX6

Gene Symbol	Gene ID	Gene Info
SOX6 Ensembl NCBI GeneCards UniProt	ENSG00000110693.19	SOX6

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr12_+_6226136 Show fit	14.96	ENST00000676764.1 ENST00000646407.1	CD9 Ensembl NCBI GeneCards UniProt Show fit	CD9 molecule
chr6_-_106974721 Show fit	13.26	ENST00000606017.2 ENST00000620405.1	CD24 Ensembl NCBI GeneCards UniProt Show fit	CD24 molecule
chr5_+_102808057 Show fit	13.21	ENST00000684043.1 ENST00000682407.1	PAM Ensembl NCBI GeneCards UniProt Show fit	peptidylglycine alpha-amidating monooxygenase
chr16_+_3018390 Show fit	12.47	ENST00000573001.5	TNFRSF12A Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 12A
chr7_+_134779663 Show fit	12.26	ENST00000361901.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr13_-_110307131 Show fit	11.92	ENST00000543140.6 ENST00000375820.10	COL4A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type IV alpha 1 chain
chr1_-_25906457 Show fit	11.00	ENST00000426559.6	STMN1 Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr7_+_134779625 Show fit	10.67	ENST00000454108.5 ENST00000361675.7	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr6_+_113857333 Show fit	10.37	ENST00000612661.2	MARCKS Ensembl NCBI GeneCards UniProt Show fit	myristoylated alanine rich protein kinase C substrate
chr4_+_41612892 Show fit	10.26	ENST00000509454.5 ENST00000396595.7 ENST00000381753.8	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr6_-_134318097 Show fit	9.63	ENST00000367858.10 ENST00000533224.1	SGK1 Ensembl NCBI GeneCards UniProt Show fit	serum/glucocorticoid regulated kinase 1
chr12_-_52926459 Show fit	9.14	ENST00000552150.5	KRT8 Ensembl NCBI GeneCards UniProt Show fit	keratin 8
chr13_+_110307276 Show fit	9.11	ENST00000360467.7 ENST00000650540.1	COL4A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type IV alpha 2 chain
chr1_-_201507116 Show fit	8.88	ENST00000340006.7 ENST00000526256.5 ENST00000526723.5 ENST00000524951.5	CSRP1 Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 1
chr4_+_41612702 Show fit	8.76	ENST00000509277.5	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr7_-_108003122 Show fit	8.37	ENST00000393559.2 ENST00000222399.11 ENST00000676777.1 ENST00000439976.6 ENST00000393560.5 ENST00000677793.1 ENST00000679244.1	LAMB1 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 1
chr3_-_120450981 Show fit	8.29	ENST00000424703.6 ENST00000469005.1 ENST00000295633.8	FSTL1 Ensembl NCBI GeneCards UniProt Show fit	follistatin like 1
chr11_-_102452758 Show fit	8.12	ENST00000398136.7 ENST00000361236.7	TMEM123 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 123
chr5_-_39425187 Show fit	7.78	ENST00000545653.5	DAB2 Ensembl NCBI GeneCards UniProt Show fit	DAB adaptor protein 2
chr2_-_37671633 Show fit	7.77	ENST00000295324.4	CDC42EP3 Ensembl NCBI GeneCards UniProt Show fit	CDC42 effector protein 3
chr15_+_76931704 Show fit	7.48	ENST00000320963.9 ENST00000394885.8 ENST00000394883.3	RCN2 Ensembl NCBI GeneCards UniProt Show fit	reticulocalbin 2
chr1_-_94927079 Show fit	7.42	ENST00000370206.9 ENST00000394202.8	CNN3 Ensembl NCBI GeneCards UniProt Show fit	calponin 3
chr2_-_1744442 Show fit	7.30	ENST00000433670.5 ENST00000425171.1 ENST00000252804.9	PXDN Ensembl NCBI GeneCards UniProt Show fit	peroxidasin
chr12_+_53097656 Show fit	7.29	ENST00000301464.4	IGFBP6 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 6
chr2_-_86563382 Show fit	7.28	ENST00000263856.9	CHMP3 Ensembl NCBI GeneCards UniProt Show fit	charged multivesicular body protein 3
chr18_+_3451647 Show fit	7.14	ENST00000345133.9 ENST00000330513.10 ENST00000549546.5	TGIF1 Ensembl NCBI GeneCards UniProt Show fit	TGFB induced factor homeobox 1
chr4_+_87975667 Show fit	7.09	ENST00000237623.11 ENST00000682655.1 ENST00000508233.6 ENST00000360804.4 ENST00000395080.8	SPP1 Ensembl NCBI GeneCards UniProt Show fit	secreted phosphoprotein 1
chr3_-_123620496 Show fit	6.89	ENST00000578202.1	MYLK Ensembl NCBI GeneCards UniProt Show fit	myosin light chain kinase
chr17_-_42136431 Show fit	6.88	ENST00000552162.5 ENST00000550504.5	RAB5C Ensembl NCBI GeneCards UniProt Show fit	RAB5C, member RAS oncogene family
chr3_-_123620571 Show fit	6.83	ENST00000583087.5	MYLK Ensembl NCBI GeneCards UniProt Show fit	myosin light chain kinase
chr16_+_33802683 Show fit	6.76	ENST00000570121.2	IGHV3OR16-12 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr12_-_57752265 Show fit	6.75	ENST00000547281.5 ENST00000257904.11 ENST00000546489.5 ENST00000552388.1	CDK4 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 4
chr7_+_77538059 Show fit	6.48	ENST00000435495.6	PTPN12 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 12
chr18_+_3449817 Show fit	6.46	ENST00000407501.6	TGIF1 Ensembl NCBI GeneCards UniProt Show fit	TGFB induced factor homeobox 1
chr5_-_39424966 Show fit	6.40	ENST00000515700.5 ENST00000320816.11 ENST00000339788.10	DAB2 Ensembl NCBI GeneCards UniProt Show fit	DAB adaptor protein 2
chr18_+_3450036 Show fit	6.20	ENST00000546979.5 ENST00000343820.10 ENST00000551402.1 ENST00000577543.5	TGIF1 Ensembl NCBI GeneCards UniProt Show fit	TGFB induced factor homeobox 1
chr5_+_83471736 Show fit	6.12	ENST00000265077.8	VCAN Ensembl NCBI GeneCards UniProt Show fit	versican
chr1_+_67685342 Show fit	6.11	ENST00000617962.2	GADD45A Ensembl NCBI GeneCards UniProt Show fit	growth arrest and DNA damage inducible alpha
chr2_+_10123171 Show fit	6.04	ENST00000615152.5	RRM2 Ensembl NCBI GeneCards UniProt Show fit	ribonucleotide reductase regulatory subunit M2
chr7_+_116672187 Show fit	5.99	ENST00000318493.11 ENST00000397752.8	MET Ensembl NCBI GeneCards UniProt Show fit	MET proto-oncogene, receptor tyrosine kinase
chr19_-_1568301 Show fit	5.91	ENST00000402693.5	MEX3D Ensembl NCBI GeneCards UniProt Show fit	mex-3 RNA binding family member D
chr1_+_67685170 Show fit	5.91	ENST00000370985.4 ENST00000370986.9 ENST00000650283.1 ENST00000648742.1	GADD45A Ensembl NCBI GeneCards UniProt Show fit	growth arrest and DNA damage inducible alpha
chr7_-_149028651 Show fit	5.68	ENST00000286091.9	PDIA4 Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 4
chr12_+_56041893 Show fit	5.55	ENST00000552361.1 ENST00000646449.2	RPS26 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S26
chr6_-_128520358 Show fit	5.31	ENST00000368215.7 ENST00000532331.5 ENST00000368213.9 ENST00000368207.7 ENST00000525459.1 ENST00000368226.9 ENST00000368210.7	PTPRK Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type K
chr8_-_140800535 Show fit	5.26	ENST00000521986.5 ENST00000523539.5	PTK2 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2
chr7_-_149028452 Show fit	5.25	ENST00000413966.1 ENST00000652332.1	PDIA4 Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 4
chr6_-_106975452 Show fit	5.15	ENST00000619869.1 ENST00000619133.4	CD24 Ensembl NCBI GeneCards UniProt Show fit	CD24 molecule
chr12_-_49187369 Show fit	5.11	ENST00000547939.6	TUBA1A Ensembl NCBI GeneCards UniProt Show fit	tubulin alpha 1a
chr14_-_106470788 Show fit	5.07	ENST00000434710.1	IGHV3-43 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-43
chr5_+_141359970 Show fit	5.04	ENST00000522605.2 ENST00000622527.1	PCDHGB2 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily B, 2
chr8_-_42501224 Show fit	4.90	ENST00000520262.6 ENST00000517366.1	SLC20A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 20 member 2
chr1_-_25906931 Show fit	4.86	ENST00000357865.6	STMN1 Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr12_+_69585666 Show fit	4.86	ENST00000543146.2	CCT2 Ensembl NCBI GeneCards UniProt Show fit	chaperonin containing TCP1 subunit 2
chr3_+_23810436 Show fit	4.78	ENST00000467766.5 ENST00000424381.5	UBE2E1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 E1
chr11_+_60924452 Show fit	4.75	ENST00000453848.7 ENST00000544065.5 ENST00000005286.8	TMEM132A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 132A
chr13_+_99501464 Show fit	4.74	ENST00000376387.5	TM9SF2 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 9 superfamily member 2
chr2_-_37672448 Show fit	4.73	ENST00000611976.1	CDC42EP3 Ensembl NCBI GeneCards UniProt Show fit	CDC42 effector protein 3
chr3_-_57597325 Show fit	4.66	ENST00000496292.5 ENST00000489843.1 ENST00000303436.11	ARF4 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 4
chr11_-_95910665 Show fit	4.62	ENST00000674610.1 ENST00000675660.1	MTMR2 Ensembl NCBI GeneCards UniProt Show fit	myotubularin related protein 2
chr11_-_95910824 Show fit	4.56	ENST00000674528.1 ENST00000675477.1 ENST00000675636.1	MTMR2 Ensembl NCBI GeneCards UniProt Show fit	myotubularin related protein 2
chr17_-_81512671 Show fit	4.27	ENST00000679480.1 ENST00000644774.2 ENST00000571721.6 ENST00000575842.5 ENST00000575087.5 ENST00000573283.7 ENST00000571691.6 ENST00000570382.2	ACTG1 Ensembl NCBI GeneCards UniProt Show fit	actin gamma 1
chr12_-_57752345 Show fit	4.25	ENST00000551800.5 ENST00000549606.5 ENST00000312990.10	CDK4 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 4
chrX_-_154371210 Show fit	4.21	ENST00000369856.8 ENST00000422373.6 ENST00000360319.9	FLNA Ensembl NCBI GeneCards UniProt Show fit	filamin A
chr11_-_10808913 Show fit	4.20	ENST00000527419.6 ENST00000530211.6 ENST00000339995.11 ENST00000530702.2 ENST00000524932.6 ENST00000532570.6	EIF4G2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4 gamma 2
chr1_+_40040219 Show fit	4.20	ENST00000372797.7 ENST00000372802.5 ENST00000449311.5	CAP1 Ensembl NCBI GeneCards UniProt Show fit	cyclase associated actin cytoskeleton regulatory protein 1
chr1_+_19644284 Show fit	4.17	ENST00000375136.8	NBL1 Ensembl NCBI GeneCards UniProt Show fit	NBL1, DAN family BMP antagonist
chr12_+_68610858 Show fit	4.14	ENST00000393436.9 ENST00000425247.6 ENST00000250559.14 ENST00000489473.6 ENST00000422358.6 ENST00000541167.5 ENST00000538283.5 ENST00000341355.9 ENST00000537460.5 ENST00000450214.6 ENST00000545270.5	RAP1B Ensembl NCBI GeneCards UniProt Show fit	RAP1B, member of RAS oncogene family
chr11_-_95910748 Show fit	4.13	ENST00000675933.1	MTMR2 Ensembl NCBI GeneCards UniProt Show fit	myotubularin related protein 2
chr16_+_89923333 Show fit	4.12	ENST00000315491.12 ENST00000555576.5 ENST00000554336.5 ENST00000553967.1	TUBB3 Ensembl NCBI GeneCards UniProt Show fit	tubulin beta 3 class III
chrX_+_12975216 Show fit	4.10	ENST00000380635.5	TMSB4X Ensembl NCBI GeneCards UniProt Show fit	thymosin beta 4 X-linked
chr13_-_23433676 Show fit	4.09	ENST00000682547.1 ENST00000455470.6 ENST00000382292.9	SACS Ensembl NCBI GeneCards UniProt Show fit	sacsin molecular chaperone
chr16_+_56936654 Show fit	4.04	ENST00000563911.5	HERPUD1 Ensembl NCBI GeneCards UniProt Show fit	homocysteine inducible ER protein with ubiquitin like domain 1
chr20_-_40689228 Show fit	4.02	ENST00000373313.3	MAFB Ensembl NCBI GeneCards UniProt Show fit	MAF bZIP transcription factor B
chr2_+_54456311 Show fit	3.97	ENST00000615901.4 ENST00000356805.9	SPTBN1 Ensembl NCBI GeneCards UniProt Show fit	spectrin beta, non-erythrocytic 1
chr2_-_37672178 Show fit	3.96	ENST00000457889.1	CDC42EP3 Ensembl NCBI GeneCards UniProt Show fit	CDC42 effector protein 3
chr12_+_10929229 Show fit	3.89	ENST00000381847.7 ENST00000396400.4	PRH2 Ensembl NCBI GeneCards UniProt Show fit	proline rich protein HaeIII subfamily 2
chr11_+_46381033 Show fit	3.87	ENST00000359803.7	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr6_+_30721573 Show fit	3.86	ENST00000330914.7	TUBB Ensembl NCBI GeneCards UniProt Show fit	tubulin beta class I
chr5_-_157575767 Show fit	3.83	ENST00000257527.9	ADAM19 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 19
chr5_+_141350081 Show fit	3.80	ENST00000523390.2 ENST00000611598.1	PCDHGB1 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily B, 1
chr8_+_26577843 Show fit	3.80	ENST00000311151.9	DPYSL2 Ensembl NCBI GeneCards UniProt Show fit	dihydropyrimidinase like 2
chr13_-_23433735 Show fit	3.77	ENST00000423156.2 ENST00000683210.1 ENST00000682775.1 ENST00000684497.1 ENST00000682944.1 ENST00000683489.1 ENST00000684385.1 ENST00000683680.1	SACS Ensembl NCBI GeneCards UniProt Show fit	sacsin molecular chaperone
chr2_-_9630491 Show fit	3.72	ENST00000381844.8	YWHAQ Ensembl NCBI GeneCards UniProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr10_+_102776237 Show fit	3.71	ENST00000369889.5	WBP1L Ensembl NCBI GeneCards UniProt Show fit	WW domain binding protein 1 like
chr17_+_54900795 Show fit	3.66	ENST00000348161.8	TOM1L1 Ensembl NCBI GeneCards UniProt Show fit	target of myb1 like 1 membrane trafficking protein
chr5_-_16936231 Show fit	3.63	ENST00000507288.1 ENST00000274203.13 ENST00000513610.6	MYO10 Ensembl NCBI GeneCards UniProt Show fit	myosin X
chr21_+_6111123 Show fit	3.57	ENST00000613488.3	SIK1B Ensembl NCBI GeneCards UniProt Show fit	salt inducible kinase 1B (putative)
chr8_-_101206064 Show fit	3.55	ENST00000518336.5 ENST00000520454.1	ZNF706 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 706
chr4_-_185810894 Show fit	3.45	ENST00000448662.6 ENST00000439049.5 ENST00000420158.5 ENST00000319471.13	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr20_+_63520746 Show fit	3.45	ENST00000370179.8 ENST00000370177.1	PPDPF Ensembl NCBI GeneCards UniProt Show fit	pancreatic progenitor cell differentiation and proliferation factor
chr2_+_231708511 Show fit	3.41	ENST00000341369.11 ENST00000409115.8 ENST00000409683.5	PTMA Ensembl NCBI GeneCards UniProt Show fit	prothymosin alpha
chr7_+_99408609 Show fit	3.35	ENST00000403633.6	BUD31 Ensembl NCBI GeneCards UniProt Show fit	BUD31 homolog
chr10_-_13348270 Show fit	3.32	ENST00000378614.8 ENST00000327347.10 ENST00000545675.5	SEPHS1 Ensembl NCBI GeneCards UniProt Show fit	selenophosphate synthetase 1
chr16_-_73048104 Show fit	3.31	ENST00000268489.10	ZFHX3 Ensembl NCBI GeneCards UniProt Show fit	zinc finger homeobox 3
chr14_-_106389858 Show fit	3.31	ENST00000390617.2	IGHV3-35 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-35 (non-functional)
chr12_-_8662619 Show fit	3.27	ENST00000544889.1 ENST00000543369.5	MFAP5 Ensembl NCBI GeneCards UniProt Show fit	microfibril associated protein 5
chr2_+_71068636 Show fit	3.16	ENST00000244204.11 ENST00000533981.5	NAGK Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine kinase
chr2_+_10122730 Show fit	3.08	ENST00000304567.10	RRM2 Ensembl NCBI GeneCards UniProt Show fit	ribonucleotide reductase regulatory subunit M2
chr5_+_72816643 Show fit	3.06	ENST00000337273.10 ENST00000523768.5	TNPO1 Ensembl NCBI GeneCards UniProt Show fit	transportin 1
chr9_-_71768386 Show fit	2.92	ENST00000377066.9 ENST00000377044.9	CEMIP2 Ensembl NCBI GeneCards UniProt Show fit	cell migration inducing hyaluronidase 2
chr12_+_69239627 Show fit	2.92	ENST00000551516.1	CPSF6 Ensembl NCBI GeneCards UniProt Show fit	cleavage and polyadenylation specific factor 6
chr17_+_77287891 Show fit	2.92	ENST00000449803.6 ENST00000431235.6	SEPTIN9 Ensembl NCBI GeneCards UniProt Show fit	septin 9
chr10_+_122163590 Show fit	2.89	ENST00000368999.5	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr11_+_46381194 Show fit	2.87	ENST00000533952.5	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr2_+_101697699 Show fit	2.83	ENST00000350878.8 ENST00000350198.8 ENST00000324219.8 ENST00000425019.5	MAP4K4 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 4
chr12_-_49188811 Show fit	2.81	ENST00000295766.9	TUBA1A Ensembl NCBI GeneCards UniProt Show fit	tubulin alpha 1a
chr19_+_46602050 Show fit	2.81	ENST00000599839.5 ENST00000596362.1	CALM3 Ensembl NCBI GeneCards UniProt Show fit	calmodulin 3
chr17_-_1684807 Show fit	2.76	ENST00000577001.1 ENST00000572621.5 ENST00000304992.11	PRPF8 Ensembl NCBI GeneCards UniProt Show fit	pre-mRNA processing factor 8
chr7_+_16753731 Show fit	2.75	ENST00000262067.5	TSPAN13 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 13
chr12_+_69239592 Show fit	2.73	ENST00000456847.7 ENST00000266679.8	CPSF6 Ensembl NCBI GeneCards UniProt Show fit	cleavage and polyadenylation specific factor 6
chr5_+_87267792 Show fit	2.69	ENST00000274376.11	RASA1 Ensembl NCBI GeneCards UniProt Show fit	RAS p21 protein activator 1
chr1_-_25906411 Show fit	2.62	ENST00000455785.7	STMN1 Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr11_-_62646598 Show fit	2.62	ENST00000648273.1 ENST00000356638.8 ENST00000346178.8 ENST00000534779.5 ENST00000525994.1 ENST00000540933.5	GANAB Ensembl NCBI GeneCards UniProt Show fit	glucosidase II alpha subunit
chr14_-_106235582 Show fit	2.59	ENST00000390607.2	IGHV3-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-21
chr19_+_5681140 Show fit	2.59	ENST00000579559.1 ENST00000577222.5	HSD11B1L Ensembl NCBI GeneCards UniProt Show fit RPL36 Ensembl NCBI GeneCards UniProt Show fit	hydroxysteroid 11-beta dehydrogenase 1 like ribosomal protein L36
chr20_-_44521989 Show fit	2.56	ENST00000342374.5 ENST00000255175.5	SERINC3 Ensembl NCBI GeneCards UniProt Show fit	serine incorporator 3
chr22_+_38656627 Show fit	2.51	ENST00000411557.5 ENST00000396811.6 ENST00000216029.7 ENST00000416285.5	CBY1 Ensembl NCBI GeneCards UniProt Show fit	chibby family member 1, beta catenin antagonist
chr15_+_78873723 Show fit	2.45	ENST00000559690.5 ENST00000559158.5	MORF4L1 Ensembl NCBI GeneCards UniProt Show fit	mortality factor 4 like 1
chr17_+_77376083 Show fit	2.41	ENST00000427674.6	SEPTIN9 Ensembl NCBI GeneCards UniProt Show fit	septin 9
chr14_+_55051639 Show fit	2.35	ENST00000395468.9 ENST00000622254.1	MAPK1IP1L Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 1 interacting protein 1 like
chr3_+_52685995 Show fit	2.35	ENST00000394799.6 ENST00000418458.6	GNL3 Ensembl NCBI GeneCards UniProt Show fit	G protein nucleolar 3
chr11_+_65182413 Show fit	2.28	ENST00000531068.5 ENST00000527699.5 ENST00000533909.5 ENST00000527323.5	CAPN1 Ensembl NCBI GeneCards UniProt Show fit	calpain 1
chr8_-_119673368 Show fit	2.26	ENST00000427067.6	ENPP2 Ensembl NCBI GeneCards UniProt Show fit	ectonucleotide pyrophosphatase/phosphodiesterase 2
chr9_-_83980190 Show fit	2.25	ENST00000457156.5 ENST00000376263.8 ENST00000360384.9	HNRNPK Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein K
chr4_+_70050431 Show fit	2.23	ENST00000511674.5 ENST00000246896.8	HTN1 Ensembl NCBI GeneCards UniProt Show fit	histatin 1
chr1_+_93448155 Show fit	2.22	ENST00000370253.6	FNBP1L Ensembl NCBI GeneCards UniProt Show fit	formin binding protein 1 like
chr12_+_77830886 Show fit	2.19	ENST00000397909.7 ENST00000549464.5	NAV3 Ensembl NCBI GeneCards UniProt Show fit	neuron navigator 3
chr19_+_48965304 Show fit	2.16	ENST00000331825.11	FTL Ensembl NCBI GeneCards UniProt Show fit	ferritin light chain
chr7_+_5592805 Show fit	2.16	ENST00000382361.8	FSCN1 Ensembl NCBI GeneCards UniProt Show fit	fascin actin-bundling protein 1
chr6_+_31815532 Show fit	2.15	ENST00000375651.7 ENST00000608703.1	HSPA1A Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family A (Hsp70) member 1A
chr9_-_72364504 Show fit	2.11	ENST00000237937.7 ENST00000343431.6 ENST00000376956.3	ZFAND5 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 5
chr17_-_19745369 Show fit	2.08	ENST00000573368.5 ENST00000457500.6	ALDH3A1 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 3 family member A1
chr10_+_122163426 Show fit	2.08	ENST00000360561.7	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr21_-_15064934 Show fit	2.05	ENST00000400199.5 ENST00000400202.5 ENST00000318948.7	NRIP1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor interacting protein 1
chr4_+_26321192 Show fit	2.05	ENST00000681484.1	RBPJ Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr11_+_65181920 Show fit	2.01	ENST00000279247.11 ENST00000532285.1 ENST00000534373.5	CAPN1 Ensembl NCBI GeneCards UniProt Show fit	calpain 1
chr19_+_48469354 Show fit	1.95	ENST00000452733.7 ENST00000641098.1	CYTH2 Ensembl NCBI GeneCards UniProt Show fit	cytohesin 2
chr10_+_22321056 Show fit	1.92	ENST00000376663.8	BMI1 Ensembl NCBI GeneCards UniProt Show fit	BMI1 proto-oncogene, polycomb ring finger
chr14_+_22836574 Show fit	1.92	ENST00000548162.2 ENST00000311852.11	MMP14 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 14
chr1_-_32336224 Show fit	1.87	ENST00000329421.8	MARCKSL1 Ensembl NCBI GeneCards UniProt Show fit	MARCKS like 1
chr4_-_142305935 Show fit	1.87	ENST00000511838.5	INPP4B Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-4-phosphatase type II B
chr4_+_26321365 Show fit	1.84	ENST00000505958.6	RBPJ Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr1_-_155910881 Show fit	1.82	ENST00000609492.1 ENST00000368322.7	RIT1 Ensembl NCBI GeneCards UniProt Show fit	Ras like without CAAX 1
chr20_-_35954461 Show fit	1.78	ENST00000305978.7	SCAND1 Ensembl NCBI GeneCards UniProt Show fit	SCAN domain containing 1
chr10_-_29735787 Show fit	1.77	ENST00000375400.7	SVIL Ensembl NCBI GeneCards UniProt Show fit	supervillin
chr1_+_150067279 Show fit	1.77	ENST00000643970.1 ENST00000535106.5 ENST00000369128.9	VPS45 Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 45 homolog
chr15_-_58749569 Show fit	1.75	ENST00000402627.5 ENST00000559053.1 ENST00000260408.8 ENST00000561288.1 ENST00000461408.2 ENST00000439637.5 ENST00000558004.1	ADAM10 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 10
chr3_-_115071333 Show fit	1.74	ENST00000462705.5	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr14_-_106117159 Show fit	1.73	ENST00000390601.3	IGHV3-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-11
chr10_+_122163672 Show fit	1.70	ENST00000369004.7 ENST00000260733.7	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr11_+_36296281 Show fit	1.67	ENST00000530639.6	PRR5L Ensembl NCBI GeneCards UniProt Show fit	proline rich 5 like
chr8_+_106726012 Show fit	1.66	ENST00000449762.6 ENST00000297447.10	OXR1 Ensembl NCBI GeneCards UniProt Show fit	oxidation resistance 1
chr2_-_151828408 Show fit	1.65	ENST00000295087.13	ARL5A Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 5A
chrX_+_71283577 Show fit	1.64	ENST00000420903.6 ENST00000373856.8 ENST00000678437.1 ENST00000678830.1 ENST00000677879.1 ENST00000373841.5 ENST00000276079.13 ENST00000676797.1 ENST00000678660.1 ENST00000678231.1 ENST00000677612.1 ENST00000413858.5 ENST00000450092.6	NONO Ensembl NCBI GeneCards UniProt Show fit	non-POU domain containing octamer binding
chr17_-_54968637 Show fit	1.59	ENST00000299335.8	COX11 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase copper chaperone COX11
chr12_+_22625075 Show fit	1.58	ENST00000671733.1 ENST00000335148.8 ENST00000672951.1 ENST00000266517.9	ETNK1 Ensembl NCBI GeneCards UniProt Show fit	ethanolamine kinase 1
chr1_-_93180261 Show fit	1.57	ENST00000370280.1 ENST00000479918.5	TMED5 Ensembl NCBI GeneCards UniProt Show fit	transmembrane p24 trafficking protein 5
chr8_-_30658176 Show fit	1.57	ENST00000355904.9	GTF2E2 Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIE subunit 2
chr15_+_89088417 Show fit	1.51	ENST00000569550.5 ENST00000565066.5 ENST00000565973.5 ENST00000352732.10	ABHD2 Ensembl NCBI GeneCards UniProt Show fit	abhydrolase domain containing 2, acylglycerol lipase
chr15_+_85380565 Show fit	1.48	ENST00000559362.5 ENST00000394518.7	AKAP13 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 13
chr15_+_64095967 Show fit	1.46	ENST00000559844.6 ENST00000261889.9 ENST00000625244.2 ENST00000561026.5 ENST00000558040.5	SNX1 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 1
chr1_-_25905989 Show fit	1.43	ENST00000399728.5	STMN1 Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr11_-_60952067 Show fit	1.37	ENST00000681275.1	SLC15A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 15 member 3
chr3_+_152268920 Show fit	1.36	ENST00000495875.6 ENST00000324210.10 ENST00000493459.5	MBNL1 Ensembl NCBI GeneCards UniProt Show fit	muscleblind like splicing regulator 1
chr4_-_142305826 Show fit	1.35	ENST00000514525.1	INPP4B Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-4-phosphatase type II B
chr12_+_103965863 Show fit	1.35	ENST00000392872.8 ENST00000537100.5	TDG Ensembl NCBI GeneCards UniProt Show fit	thymine DNA glycosylase
chr9_+_98943705 Show fit	1.31	ENST00000610452.1	COL15A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XV alpha 1 chain
chr8_-_28386417 Show fit	1.30	ENST00000521185.5 ENST00000520290.5 ENST00000344423.10	ZNF395 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 395
chr6_+_32969345 Show fit	1.27	ENST00000678250.1	BRD2 Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 2
chr1_+_172533104 Show fit	1.26	ENST00000616058.4 ENST00000263688.4 ENST00000610051.5	SUCO Ensembl NCBI GeneCards UniProt Show fit	SUN domain containing ossification factor
chr4_-_7939789 Show fit	1.22	ENST00000420658.6 ENST00000358461.6	AFAP1 Ensembl NCBI GeneCards UniProt Show fit	actin filament associated protein 1
chr12_-_8662808 Show fit	1.21	ENST00000359478.7 ENST00000396549.6	MFAP5 Ensembl NCBI GeneCards UniProt Show fit	microfibril associated protein 5
chr7_+_77538027 Show fit	1.17	ENST00000433369.6 ENST00000415482.6	PTPN12 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 12
chr2_-_216695540 Show fit	1.06	ENST00000233813.5	IGFBP5 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 5
chr8_-_28386073 Show fit	1.06	ENST00000523095.5 ENST00000522795.1	ZNF395 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 395
chr17_-_51046868 Show fit	1.06	ENST00000510283.5 ENST00000510855.1	SPAG9 Ensembl NCBI GeneCards UniProt Show fit	sperm associated antigen 9
chr14_+_23322019 Show fit	1.05	ENST00000557702.5	PABPN1 Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein nuclear 1
chr7_+_102912983 Show fit	1.05	ENST00000339431.9 ENST00000249377.4	LRRC17 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 17
chr4_-_185956348 Show fit	1.02	ENST00000431902.5 ENST00000284776.11 ENST00000415274.5	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr3_-_197298000 Show fit	1.02	ENST00000664991.1	DLG1 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 1
chr6_+_32969165 Show fit	0.97	ENST00000496118.2 ENST00000449085.4	BRD2 Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 2
chr11_-_79441016 Show fit	0.93	ENST00000278550.12	TENM4 Ensembl NCBI GeneCards UniProt Show fit	teneurin transmembrane protein 4
chr11_-_60952134 Show fit	0.92	ENST00000679573.1 ENST00000681882.1 ENST00000681951.1 ENST00000227880.8	SLC15A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 15 member 3
chr1_+_13585453 Show fit	0.91	ENST00000487038.5 ENST00000475043.5	PDPN Ensembl NCBI GeneCards UniProt Show fit	podoplanin
chr16_+_3654683 Show fit	0.91	ENST00000246949.10	DNASE1 Ensembl NCBI GeneCards UniProt Show fit	deoxyribonuclease 1
chr8_+_11802611 Show fit	0.89	ENST00000623368.3	FDFT1 Ensembl NCBI GeneCards UniProt Show fit	farnesyl-diphosphate farnesyltransferase 1
chr14_+_49768109 Show fit	0.89	ENST00000298307.10 ENST00000554589.5 ENST00000557247.1	KLHDC2 Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 2
chr7_+_107583919 Show fit	0.88	ENST00000491150.5	BCAP29 Ensembl NCBI GeneCards UniProt Show fit	B cell receptor associated protein 29
chr12_+_22625182 Show fit	0.87	ENST00000538218.2	ETNK1 Ensembl NCBI GeneCards UniProt Show fit	ethanolamine kinase 1
chrX_+_12975083 Show fit	0.87	ENST00000451311.7 ENST00000380636.1	TMSB4X Ensembl NCBI GeneCards UniProt Show fit	thymosin beta 4 X-linked
chr9_+_131394042 Show fit	0.85	ENST00000684596.1 ENST00000683519.1 ENST00000682501.1	PRRC2B Ensembl NCBI GeneCards UniProt Show fit	proline rich coiled-coil 2B
chr4_+_26584064 Show fit	0.84	ENST00000264866.9 ENST00000505206.5 ENST00000511789.5	TBC1D19 Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 19
chr2_+_69013414 Show fit	0.82	ENST00000681816.1 ENST00000482235.2	ANTXR1 Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr21_+_37073213 Show fit	0.82	ENST00000418766.5 ENST00000450533.5 ENST00000438055.5 ENST00000355666.5 ENST00000540756.5 ENST00000399010.5	TTC3 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 3
chr8_+_11802667 Show fit	0.80	ENST00000443614.6 ENST00000220584.9 ENST00000525900.5	FDFT1 Ensembl NCBI GeneCards UniProt Show fit	farnesyl-diphosphate farnesyltransferase 1
chr20_+_6767678 Show fit	0.79	ENST00000378827.5	BMP2 Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein 2
chr2_+_69013379 Show fit	0.79	ENST00000409349.7	ANTXR1 Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr17_+_16381462 Show fit	0.78	ENST00000578706.5 ENST00000614404.1	UBB Ensembl NCBI GeneCards UniProt Show fit	ubiquitin B
chr8_+_94641074 Show fit	0.77	ENST00000423620.6	ESRP1 Ensembl NCBI GeneCards UniProt Show fit	epithelial splicing regulatory protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.7	14.2	GO:0035026	leading edge cell differentiation(GO:0035026)
4.6	18.4	GO:0032597	B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
3.3	13.2	GO:0018032	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
3.0	11.9	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
2.4	7.1	GO:2000863	positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
2.3	13.7	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
2.2	11.0	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
2.1	12.5	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.8	21.9	GO:0070495	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.4	4.2	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.4	9.6	GO:0070294	renal sodium ion absorption(GO:0070294)
1.2	15.0	GO:0009414	response to water deprivation(GO:0009414)
1.2	13.3	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
1.0	4.2	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
1.0	4.0	GO:0035284	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
1.0	4.0	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
1.0	6.7	GO:0030421	defecation(GO:0030421)
0.9	13.9	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.8	7.6	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.7	7.3	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.7	4.9	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.7	3.3	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.7	9.1	GO:0009415	response to water(GO:0009415) response to hydrostatic pressure(GO:0051599)
0.7	9.1	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.6	5.0	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) negative regulation of interleukin-8 secretion(GO:2000483)
0.6	4.8	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.6	2.2	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.6	3.4	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.6	10.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.6	3.9	GO:0060844	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.5	8.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.5	2.2	GO:0030035	microspike assembly(GO:0030035)
0.5	6.9	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.5	3.2	GO:0006050	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.5	4.7	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.5	12.8	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.5	3.5	GO:0031017	exocrine pancreas development(GO:0031017)
0.5	1.9	GO:1990834	response to odorant(GO:1990834)
0.5	0.9	GO:0032289	central nervous system myelin formation(GO:0032289)
0.5	5.9	GO:0008298	intracellular mRNA localization(GO:0008298)
0.5	10.4	GO:0051764	actin crosslink formation(GO:0051764)
0.4	4.9	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.4	1.8	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.4	2.2	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
0.4	3.3	GO:0001887	selenium compound metabolic process(GO:0001887)
0.4	5.3	GO:0051964	netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.4	7.4	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.4	9.1	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.4	4.3	GO:0060056	mammary gland involution(GO:0060056)
0.4	1.1	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.3	1.0	GO:1904247	regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.3	1.3	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
0.3	4.0	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3	5.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.3	2.6	GO:0009597	detection of virus(GO:0009597)
0.3	2.2	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3	0.9	GO:1904328	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.3	1.7	GO:0008204	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.3	6.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.2	6.4	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.2	0.9	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2	7.0	GO:0030033	microvillus assembly(GO:0030033)
0.2	7.3	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2	2.8	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2	1.0	GO:0048539	bone marrow development(GO:0048539)
0.2	3.5	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.2	1.6	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2	3.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.2	1.8	GO:1902255	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) fat pad development(GO:0060613) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527)
0.2	1.9	GO:0007379	segment specification(GO:0007379)
0.2	14.3	GO:0006910	phagocytosis, recognition(GO:0006910)
0.2	3.7	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2	2.4	GO:1904816	positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.2	1.1	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.2	2.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.2	8.4	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1	0.7	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	13.2	GO:0070527	platelet aggregation(GO:0070527)
0.1	1.7	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	2.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	4.5	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	5.5	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.1	2.5	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.1	1.7	GO:0038203	TORC2 signaling(GO:0038203)
0.1	9.7	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	4.5	GO:0097435	fibril organization(GO:0097435)
0.1	0.3	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	1.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.1	2.2	GO:0097320	membrane tubulation(GO:0097320)
0.1	1.6	GO:0090161	Golgi ribbon formation(GO:0090161)
0.1	4.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.1	0.8	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.1	2.9	GO:0048745	smooth muscle tissue development(GO:0048745)
0.1	0.1	GO:0035549	positive regulation of interferon-beta secretion(GO:0035549)
0.1	3.7	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1	1.5	GO:0048240	sperm capacitation(GO:0048240)
0.1	4.8	GO:0010507	negative regulation of autophagy(GO:0010507)
0.1	2.7	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
0.1	2.2	GO:0050832	defense response to fungus(GO:0050832)
0.1	3.9	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.1	0.6	GO:0051601	exocyst localization(GO:0051601)
0.1	1.3	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.1	0.3	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.0	8.3	GO:0042594	response to starvation(GO:0042594)
0.0	18.8	GO:0042493	response to drug(GO:0042493)
0.0	5.8	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0	7.3	GO:0031032	actomyosin structure organization(GO:0031032)
0.0	4.4	GO:0021987	cerebral cortex development(GO:0021987)
0.0	0.8	GO:0007143	female meiotic division(GO:0007143)
0.0	2.7	GO:1903169	regulation of calcium ion transmembrane transport(GO:1903169)
0.0	1.8	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	1.7	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	1.8	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.4	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	17.1	GO:0006936	muscle contraction(GO:0006936)
0.0	2.5	GO:0051289	protein homotetramerization(GO:0051289)
0.0	8.2	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0	2.6	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	2.5	GO:0000725	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0	0.9	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.4	GO:0016540	protein autoprocessing(GO:0016540)
0.0	2.5	GO:0006334	nucleosome assembly(GO:0006334)
0.0	2.8	GO:0015992	proton transport(GO:0015992)
0.0	0.1	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.6	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.0	1.6	GO:0042795	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	1.2	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	0.8	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	0.5	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.8	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.8	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0051572	negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	8.4	GO:0005606	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
2.6	21.0	GO:0005587	collagen type IV trimer(GO:0005587)
2.4	14.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
2.3	9.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
1.8	11.0	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
1.5	22.9	GO:0030478	actin cap(GO:0030478)
0.8	4.2	GO:0031523	Myb complex(GO:0031523)
0.8	7.9	GO:0070852	cell body fiber(GO:0070852)
0.8	18.4	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.7	2.2	GO:0044393	microspike(GO:0044393)
0.7	8.4	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.7	4.0	GO:0032437	cuticular plate(GO:0032437)
0.6	10.4	GO:0043073	germ cell nucleus(GO:0043073)
0.6	5.6	GO:0042382	paraspeckles(GO:0042382)
0.6	4.0	GO:1990037	Lewy body core(GO:1990037)
0.6	7.3	GO:0000815	ESCRT III complex(GO:0000815)
0.5	2.2	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.4	1.3	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.4	3.9	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3	18.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.3	4.3	GO:0097433	dense body(GO:0097433)
0.3	1.9	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.3	9.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.3	2.7	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.3	4.8	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3	5.8	GO:0031527	filopodium membrane(GO:0031527)
0.3	4.9	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.2	11.7	GO:0002102	podosome(GO:0002102)
0.2	8.8	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2	4.5	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.2	1.5	GO:0030905	retromer, tubulation complex(GO:0030905)
0.2	13.7	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2	3.9	GO:0005641	nuclear envelope lumen(GO:0005641)
0.2	2.7	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	11.0	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	1.5	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	2.5	GO:0016580	Sin3 complex(GO:0016580)
0.1	1.9	GO:0035102	PRC1 complex(GO:0035102)
0.1	42.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	7.9	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	22.2	GO:0043197	dendritic spine(GO:0043197)
0.1	2.8	GO:0005682	U5 snRNP(GO:0005682)
0.1	5.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	1.7	GO:0031932	TORC2 complex(GO:0031932)
0.1	1.8	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	2.3	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	0.8	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	0.5	GO:0061689	tricellular tight junction(GO:0061689)
0.1	1.6	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	5.0	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	4.4	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	1.0	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	13.2	GO:0030667	secretory granule membrane(GO:0030667)
0.0	25.3	GO:0005925	focal adhesion(GO:0005925)
0.0	4.2	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	19.2	GO:0005874	microtubule(GO:0005874)
0.0	2.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.3	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.6	GO:0000145	exocyst(GO:0000145)
0.0	6.1	GO:0001726	ruffle(GO:0001726)
0.0	0.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	17.2	GO:0016607	nuclear speck(GO:0016607)
0.0	0.3	GO:0005579	membrane attack complex(GO:0005579)
0.0	2.8	GO:0000922	spindle pole(GO:0000922)
0.0	5.6	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	3.3	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.1	GO:1903349	omegasome membrane(GO:1903349)
0.0	4.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.4	GO:0005771	multivesicular body(GO:0005771)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.5	16.5	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
3.4	13.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
3.3	13.2	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
2.3	9.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.7	11.9	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
1.5	7.3	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
1.3	3.8	GO:0004157	dihydropyrimidinase activity(GO:0004157)
1.0	4.9	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
1.0	4.8	GO:0042296	ISG15 transferase activity(GO:0042296)
0.8	4.2	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.8	22.1	GO:0005523	tropomyosin binding(GO:0005523)
0.8	3.2	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.7	8.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.7	19.8	GO:0070410	co-SMAD binding(GO:0070410)
0.6	3.2	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.6	14.2	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.6	4.2	GO:0016015	morphogen activity(GO:0016015)
0.6	7.6	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.6	2.3	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.5	10.9	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.5	11.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.5	18.4	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.5	3.6	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.5	1.4	GO:0001069	regulatory region RNA binding(GO:0001069)
0.4	1.3	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.4	2.5	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.4	7.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.4	2.3	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.4	9.6	GO:0017081	chloride channel regulator activity(GO:0017081)
0.4	2.8	GO:0004111	creatine kinase activity(GO:0004111)
0.3	7.7	GO:0070628	proteasome binding(GO:0070628)
0.3	2.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3	2.8	GO:0030620	U2 snRNA binding(GO:0030620)
0.3	18.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.3	6.3	GO:0008432	JUN kinase binding(GO:0008432)
0.3	2.6	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.3	29.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.3	1.5	GO:1990460	leptin receptor binding(GO:1990460)
0.3	1.7	GO:0004310	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.3	1.9	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.3	10.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2	6.9	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2	3.9	GO:0000150	recombinase activity(GO:0000150)
0.2	4.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.2	2.2	GO:0008199	ferric iron binding(GO:0008199)
0.2	5.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.2	2.2	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.2	4.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.2	0.9	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.2	2.0	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2	2.1	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2	0.8	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.1	3.9	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	3.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	4.9	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	8.6	GO:0005080	protein kinase C binding(GO:0005080)
0.1	11.0	GO:0019003	GDP binding(GO:0019003)
0.1	4.0	GO:0030506	ankyrin binding(GO:0030506)
0.1	5.0	GO:0003785	actin monomer binding(GO:0003785)
0.1	18.6	GO:0005178	integrin binding(GO:0005178)
0.1	7.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	8.9	GO:0097110	scaffold protein binding(GO:0097110)
0.1	4.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	1.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	16.7	GO:0047485	protein N-terminus binding(GO:0047485)
0.1	4.7	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	2.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	0.8	GO:0039706	co-receptor binding(GO:0039706)
0.1	12.0	GO:0008201	heparin binding(GO:0008201)
0.1	2.9	GO:0017091	AU-rich element binding(GO:0017091)
0.1	4.8	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	3.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	3.7	GO:0030276	clathrin binding(GO:0030276)
0.1	0.9	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	9.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	2.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	2.7	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.8	GO:0097016	L27 domain binding(GO:0097016)
0.0	10.2	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	2.1	GO:0050681	androgen receptor binding(GO:0050681)
0.0	18.3	GO:0003779	actin binding(GO:0003779)
0.0	4.0	GO:0044325	ion channel binding(GO:0044325)
0.0	0.7	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	1.9	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.4	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	1.0	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	2.2	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.3	GO:0008198	ferrous iron binding(GO:0008198)
0.0	2.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	2.1	GO:0003823	antigen binding(GO:0003823)
0.0	0.0	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0	3.6	GO:0005525	GTP binding(GO:0005525)
0.0	1.4	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.0	3.0	GO:0015631	tubulin binding(GO:0015631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	17.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.7	30.7	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.4	7.8	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4	24.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.3	12.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.3	20.8	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.2	11.2	PID INSULIN PATHWAY	Insulin Pathway
0.2	9.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	10.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	17.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.2	13.8	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.2	6.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.2	24.0	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	2.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	5.6	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	3.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	7.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	4.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.1	7.9	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	20.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	5.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	2.0	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	2.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	9.1	PID E2F PATHWAY	E2F transcription factor network
0.1	2.0	PID ARF 3PATHWAY	Arf1 pathway
0.1	5.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	4.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.1	1.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	2.1	PID FOXO PATHWAY	FoxO family signaling
0.0	5.3	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	1.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	1.1	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	1.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.8	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	1.8	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	16.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.8	9.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.7	39.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.7	14.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.5	16.4	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.4	9.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.4	19.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3	8.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	22.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	11.0	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.3	9.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.3	3.9	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.3	1.8	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	4.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2	6.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	30.7	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.2	4.8	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.2	7.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	4.0	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.2	2.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	3.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2	2.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	19.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	9.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.8	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	3.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	6.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	5.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	3.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	1.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	1.0	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	1.9	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.1	2.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.1	4.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	4.2	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	1.6	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	6.6	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.6	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	2.8	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	2.6	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling

Results for SOX6

Z-value: 1.23

Motif logo

Transcription factors associated with SOX6

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: