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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for SP1
Z-value: 6.44
Motif logo
Transcription factors associated with SP1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SP1
|
ENSG00000185591.10 | SP1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SP1 | hg38_v1_chr12_+_53380639_53380874, hg38_v1_chr12_+_53380141_53380210 | -0.64 | 1.0e-26 | Click! |
Activity profile of SP1 motif
Sorted Z-values of SP1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of SP1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 25.9 | 103.5 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 23.1 | 92.3 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 22.7 | 90.8 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 21.9 | 65.8 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 21.6 | 86.5 | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) |
| 20.2 | 80.9 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 20.1 | 20.1 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 19.2 | 96.1 | GO:0019322 | pentose biosynthetic process(GO:0019322) |
| 17.6 | 17.6 | GO:0071211 | protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) protein targeting to vacuole involved in autophagy(GO:0071211) |
| 16.2 | 64.8 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 15.7 | 62.9 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 15.6 | 62.4 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 15.4 | 77.0 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 15.3 | 168.5 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 14.9 | 59.5 | GO:0009224 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 14.8 | 59.0 | GO:0002188 | translation reinitiation(GO:0002188) |
| 14.7 | 73.5 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 14.5 | 58.1 | GO:0016334 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 14.1 | 28.1 | GO:0090579 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 13.9 | 69.4 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 13.6 | 190.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 13.6 | 135.5 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 13.2 | 39.5 | GO:0060957 | endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445) |
| 13.1 | 91.4 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 13.0 | 77.8 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 12.6 | 50.4 | GO:0006169 | adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) |
| 12.6 | 12.6 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
| 12.3 | 73.5 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 12.1 | 60.6 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 12.0 | 36.0 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 12.0 | 36.0 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 11.9 | 59.7 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 11.9 | 47.7 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 11.8 | 35.3 | GO:0090176 | microtubule cytoskeleton organization involved in establishment of planar polarity(GO:0090176) |
| 11.8 | 117.7 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 11.6 | 34.8 | GO:1902822 | regulation of late endosome to lysosome transport(GO:1902822) |
| 11.6 | 34.7 | GO:1903233 | regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) |
| 11.4 | 80.0 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 11.3 | 79.2 | GO:0030421 | defecation(GO:0030421) |
| 11.3 | 33.8 | GO:0060382 | regulation of DNA strand elongation(GO:0060382) |
| 11.2 | 33.5 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 11.2 | 33.5 | GO:1901874 | negative regulation of post-translational protein modification(GO:1901874) |
| 11.0 | 121.0 | GO:0085020 | protein K6-linked ubiquitination(GO:0085020) |
| 11.0 | 32.9 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
| 10.9 | 54.5 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 10.9 | 65.4 | GO:0002840 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) |
| 10.7 | 128.6 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 10.7 | 96.2 | GO:0060613 | fat pad development(GO:0060613) |
| 10.6 | 232.3 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 10.5 | 31.6 | GO:1902594 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 10.5 | 52.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 10.5 | 31.4 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 10.4 | 31.3 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 10.4 | 31.2 | GO:1903382 | neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382) |
| 10.4 | 72.6 | GO:0033183 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 10.3 | 237.1 | GO:0051639 | actin filament network formation(GO:0051639) |
| 10.2 | 30.7 | GO:2000276 | negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) |
| 10.2 | 61.3 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 10.2 | 50.9 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 10.0 | 50.1 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 9.9 | 89.5 | GO:2000582 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 9.9 | 29.8 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 9.8 | 78.6 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 9.8 | 49.1 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 9.4 | 37.7 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 9.3 | 37.2 | GO:0035900 | response to isolation stress(GO:0035900) |
| 9.3 | 27.8 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 9.2 | 27.6 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 9.0 | 107.7 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 8.9 | 26.8 | GO:0061573 | endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650) |
| 8.9 | 17.9 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 8.9 | 8.9 | GO:0071464 | cellular response to hydrostatic pressure(GO:0071464) |
| 8.9 | 44.5 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 8.9 | 62.2 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 8.7 | 43.5 | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 8.7 | 34.8 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
| 8.6 | 8.6 | GO:1903911 | positive regulation of receptor clustering(GO:1903911) |
| 8.6 | 25.8 | GO:1902267 | polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269) |
| 8.5 | 34.0 | GO:0036114 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 8.4 | 25.2 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 8.4 | 108.6 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 8.4 | 8.4 | GO:0060221 | retinal rod cell differentiation(GO:0060221) |
| 8.3 | 33.3 | GO:0070982 | L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982) |
| 8.3 | 8.3 | GO:2000586 | regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) |
| 8.2 | 41.2 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 8.2 | 24.7 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 8.2 | 73.9 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 8.2 | 73.9 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 8.2 | 164.1 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 8.2 | 24.6 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 8.1 | 24.3 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 7.9 | 23.7 | GO:1902905 | positive regulation of fibril organization(GO:1902905) |
| 7.9 | 70.9 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 7.9 | 55.1 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 7.8 | 23.5 | GO:1903296 | regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296) |
| 7.8 | 7.8 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 7.8 | 23.4 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 7.8 | 31.1 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 7.7 | 69.5 | GO:0006265 | DNA topological change(GO:0006265) |
| 7.7 | 54.0 | GO:0007144 | female meiosis I(GO:0007144) |
| 7.7 | 54.0 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 7.6 | 45.7 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 7.5 | 128.0 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 7.5 | 22.5 | GO:0003420 | regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) |
| 7.5 | 14.9 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 7.3 | 307.9 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 7.3 | 22.0 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 7.3 | 14.6 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 7.2 | 108.5 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 7.2 | 28.9 | GO:0043335 | protein unfolding(GO:0043335) |
| 7.1 | 14.3 | GO:0032075 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) positive regulation of nuclease activity(GO:0032075) |
| 7.1 | 28.4 | GO:2000259 | positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 7.1 | 21.3 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
| 7.0 | 35.2 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 7.0 | 77.1 | GO:1903297 | regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) |
| 7.0 | 27.9 | GO:0001519 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 7.0 | 27.9 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 7.0 | 27.8 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 6.9 | 62.3 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 6.9 | 48.4 | GO:0032218 | riboflavin transport(GO:0032218) |
| 6.9 | 61.7 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 6.8 | 109.1 | GO:0043248 | proteasome assembly(GO:0043248) |
| 6.8 | 20.4 | GO:1903572 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 6.8 | 33.9 | GO:1904764 | late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 6.8 | 20.3 | GO:0009085 | lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) |
| 6.7 | 47.1 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 6.7 | 6.7 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 6.6 | 105.8 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 6.6 | 39.3 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 6.5 | 137.1 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 6.5 | 6.5 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 6.5 | 25.8 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 6.4 | 6.4 | GO:0044209 | AMP salvage(GO:0044209) |
| 6.4 | 83.5 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 6.4 | 95.8 | GO:0000338 | protein deneddylation(GO:0000338) |
| 6.4 | 19.1 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 6.4 | 31.9 | GO:1900368 | regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) |
| 6.4 | 38.2 | GO:0097052 | L-kynurenine metabolic process(GO:0097052) |
| 6.4 | 19.1 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 6.3 | 107.7 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 6.3 | 37.9 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 6.3 | 18.9 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
| 6.3 | 31.5 | GO:0009133 | nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188) |
| 6.3 | 18.8 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 6.2 | 37.4 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
| 6.2 | 24.9 | GO:0090096 | metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 6.2 | 12.4 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
| 6.2 | 31.0 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 6.2 | 18.6 | GO:1902462 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 6.1 | 36.9 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 6.1 | 6.1 | GO:0018197 | peptidyl-aspartic acid modification(GO:0018197) |
| 6.1 | 24.5 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 6.1 | 36.4 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 6.1 | 54.5 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 6.1 | 12.1 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 6.0 | 12.1 | GO:0009149 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) |
| 6.0 | 18.1 | GO:1990144 | intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144) |
| 6.0 | 84.4 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 6.0 | 18.1 | GO:0045715 | negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
| 6.0 | 12.0 | GO:1904378 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 6.0 | 41.9 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 6.0 | 12.0 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 6.0 | 35.9 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 6.0 | 6.0 | GO:1904528 | positive regulation of microtubule binding(GO:1904528) |
| 5.9 | 23.7 | GO:0030047 | actin modification(GO:0030047) |
| 5.9 | 17.7 | GO:0002905 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 5.9 | 35.3 | GO:0006696 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) |
| 5.9 | 35.2 | GO:0033490 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 5.9 | 17.6 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 5.8 | 17.5 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 5.8 | 58.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 5.8 | 40.7 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 5.7 | 17.2 | GO:0031456 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 5.7 | 11.4 | GO:1903721 | regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) |
| 5.7 | 11.4 | GO:0070476 | RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 5.7 | 11.4 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 5.7 | 39.6 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
| 5.6 | 39.4 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 5.6 | 11.2 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 5.6 | 16.8 | GO:1904245 | regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 5.6 | 33.6 | GO:1904688 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 5.6 | 16.8 | GO:1900163 | regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755) |
| 5.6 | 16.7 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 5.6 | 44.5 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 5.6 | 16.7 | GO:0060295 | regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 5.5 | 22.2 | GO:0032077 | positive regulation of deoxyribonuclease activity(GO:0032077) |
| 5.5 | 33.2 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 5.5 | 38.7 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 5.5 | 22.0 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 5.5 | 22.0 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 5.5 | 32.9 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 5.5 | 27.4 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 5.4 | 10.8 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
| 5.4 | 10.8 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 5.4 | 48.7 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 5.4 | 32.5 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 5.4 | 5.4 | GO:1902954 | regulation of early endosome to recycling endosome transport(GO:1902954) |
| 5.4 | 91.5 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 5.3 | 10.7 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 5.3 | 16.0 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 5.3 | 37.2 | GO:0044334 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 5.3 | 31.8 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 5.3 | 5.3 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
| 5.3 | 84.1 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 5.3 | 31.5 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 5.2 | 15.7 | GO:0042532 | negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532) |
| 5.2 | 26.2 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 5.2 | 15.7 | GO:1902965 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 5.2 | 73.1 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 5.2 | 15.6 | GO:0010225 | response to UV-C(GO:0010225) |
| 5.2 | 10.4 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 5.2 | 51.7 | GO:0033523 | histone H2B ubiquitination(GO:0033523) |
| 5.2 | 20.7 | GO:0044571 | [2Fe-2S] cluster assembly(GO:0044571) |
| 5.1 | 20.6 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 5.1 | 66.5 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 5.1 | 15.3 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 5.1 | 91.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 5.1 | 71.1 | GO:0042761 | fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 5.0 | 30.2 | GO:0015680 | intracellular copper ion transport(GO:0015680) |
| 5.0 | 15.0 | GO:0060623 | regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283) |
| 5.0 | 20.1 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 5.0 | 35.1 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
| 5.0 | 40.0 | GO:0052405 | negative regulation by host of symbiont molecular function(GO:0052405) |
| 5.0 | 24.8 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 4.9 | 19.8 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 4.9 | 73.9 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 4.9 | 24.6 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 4.9 | 49.0 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 4.9 | 93.1 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 4.9 | 24.5 | GO:1904398 | positive regulation of neuromuscular junction development(GO:1904398) |
| 4.9 | 9.8 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
| 4.8 | 33.8 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 4.8 | 100.8 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 4.8 | 90.5 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 4.8 | 28.5 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 4.7 | 14.2 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 4.7 | 18.9 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 4.7 | 14.1 | GO:1902568 | positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
| 4.7 | 9.4 | GO:0042823 | pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) |
| 4.7 | 182.1 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 4.7 | 14.0 | GO:0051793 | medium-chain fatty acid catabolic process(GO:0051793) |
| 4.6 | 27.8 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 4.6 | 18.5 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 4.6 | 23.1 | GO:0015862 | uridine transport(GO:0015862) |
| 4.6 | 4.6 | GO:0009838 | abscission(GO:0009838) |
| 4.6 | 9.1 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 4.5 | 13.6 | GO:0001927 | exocyst assembly(GO:0001927) |
| 4.5 | 9.0 | GO:0060699 | regulation of endoribonuclease activity(GO:0060699) |
| 4.5 | 40.5 | GO:0075713 | establishment of integrated proviral latency(GO:0075713) |
| 4.5 | 22.4 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 4.5 | 4.5 | GO:0098902 | regulation of membrane depolarization during action potential(GO:0098902) |
| 4.5 | 13.4 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 4.5 | 31.2 | GO:0010710 | regulation of collagen catabolic process(GO:0010710) |
| 4.5 | 26.7 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 4.4 | 17.7 | GO:0035750 | protein localization to myelin sheath abaxonal region(GO:0035750) |
| 4.4 | 13.2 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 4.4 | 13.2 | GO:1900223 | positive regulation of beta-amyloid clearance(GO:1900223) |
| 4.4 | 17.6 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 4.4 | 96.6 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 4.4 | 21.9 | GO:0080009 | mRNA methylation(GO:0080009) |
| 4.4 | 13.1 | GO:0008615 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) |
| 4.4 | 34.9 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 4.3 | 13.0 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 4.3 | 12.9 | GO:1904579 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910) |
| 4.3 | 8.6 | GO:0014858 | positive regulation of skeletal muscle cell proliferation(GO:0014858) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
| 4.3 | 29.9 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 4.3 | 21.3 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 4.3 | 17.0 | GO:2000674 | regulation of type B pancreatic cell apoptotic process(GO:2000674) |
| 4.2 | 4.2 | GO:0019858 | cytosine metabolic process(GO:0019858) |
| 4.2 | 12.7 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 4.2 | 55.0 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 4.2 | 16.9 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 4.2 | 4.2 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 4.2 | 12.6 | GO:0097069 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 4.2 | 12.5 | GO:0072334 | UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334) |
| 4.2 | 8.3 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 4.2 | 249.6 | GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) |
| 4.2 | 37.4 | GO:0090343 | positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774) |
| 4.1 | 37.0 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 4.1 | 8.2 | GO:0097252 | oligodendrocyte apoptotic process(GO:0097252) |
| 4.1 | 20.5 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 4.1 | 24.6 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 4.1 | 16.2 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 4.1 | 40.6 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 4.1 | 4.1 | GO:0071072 | negative regulation of phospholipid biosynthetic process(GO:0071072) |
| 4.0 | 12.1 | GO:0018317 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 4.0 | 24.1 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 4.0 | 27.7 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 4.0 | 67.3 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 4.0 | 110.7 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 3.9 | 106.5 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 3.9 | 35.4 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 3.9 | 82.6 | GO:0032060 | bleb assembly(GO:0032060) |
| 3.9 | 3.9 | GO:0021539 | subthalamus development(GO:0021539) |
| 3.9 | 3.9 | GO:0035087 | siRNA loading onto RISC involved in RNA interference(GO:0035087) |
| 3.9 | 132.6 | GO:0090383 | phagosome acidification(GO:0090383) |
| 3.9 | 15.5 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 3.8 | 42.1 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 3.8 | 282.7 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 3.7 | 11.2 | GO:0042727 | flavin-containing compound biosynthetic process(GO:0042727) |
| 3.7 | 82.1 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 3.7 | 7.5 | GO:1904116 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 3.7 | 52.1 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
| 3.7 | 11.2 | GO:0036363 | transforming growth factor beta activation(GO:0036363) |
| 3.7 | 29.5 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 3.7 | 7.4 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 3.7 | 11.0 | GO:0052572 | response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) |
| 3.7 | 22.0 | GO:0015853 | adenine transport(GO:0015853) |
| 3.7 | 14.7 | GO:0070885 | negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) |
| 3.6 | 18.2 | GO:0009240 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490) |
| 3.6 | 18.2 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 3.6 | 7.2 | GO:0046086 | adenosine biosynthetic process(GO:0046086) |
| 3.6 | 10.9 | GO:0014040 | acetaldehyde metabolic process(GO:0006117) regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040) |
| 3.6 | 7.2 | GO:0061312 | BMP signaling pathway involved in heart development(GO:0061312) |
| 3.6 | 10.9 | GO:1990441 | negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441) |
| 3.6 | 7.2 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 3.6 | 28.8 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 3.6 | 25.1 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 3.6 | 107.4 | GO:0006625 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 3.6 | 35.6 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 3.6 | 231.1 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
| 3.5 | 53.2 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 3.5 | 21.2 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 3.5 | 77.5 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 3.5 | 7.0 | GO:0005997 | xylulose metabolic process(GO:0005997) |
| 3.5 | 3.5 | GO:1903895 | negative regulation of IRE1-mediated unfolded protein response(GO:1903895) |
| 3.5 | 14.0 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 3.5 | 14.0 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 3.5 | 10.5 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 3.5 | 110.6 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 3.5 | 34.5 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
| 3.4 | 10.3 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 3.4 | 96.3 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 3.4 | 27.4 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 3.4 | 13.6 | GO:1904044 | response to aldosterone(GO:1904044) |
| 3.4 | 13.6 | GO:0009956 | radial pattern formation(GO:0009956) |
| 3.4 | 256.5 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 3.4 | 13.5 | GO:0046946 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 3.4 | 47.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 3.4 | 10.1 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 3.4 | 13.5 | GO:0044857 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) |
| 3.4 | 3.4 | GO:2000670 | positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 3.3 | 83.7 | GO:0006465 | signal peptide processing(GO:0006465) |
| 3.3 | 3.3 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 3.3 | 46.5 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 3.3 | 9.9 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
| 3.3 | 9.9 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 3.3 | 52.6 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 3.3 | 19.7 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 3.3 | 22.9 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
| 3.3 | 22.9 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 3.3 | 35.8 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
| 3.2 | 3.2 | GO:2000644 | regulation of receptor catabolic process(GO:2000644) |
| 3.2 | 3.2 | GO:0090107 | regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 3.2 | 12.9 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 3.2 | 32.2 | GO:0051561 | positive regulation of mitochondrial calcium ion concentration(GO:0051561) |
| 3.2 | 3.2 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 3.2 | 3.2 | GO:0061054 | dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184) regulation of testosterone biosynthetic process(GO:2000224) |
| 3.2 | 51.4 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 3.2 | 9.6 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 3.2 | 12.8 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 3.2 | 35.0 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 3.2 | 38.1 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 3.2 | 44.4 | GO:0070986 | left/right axis specification(GO:0070986) |
| 3.2 | 22.1 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 3.2 | 22.1 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 3.1 | 15.7 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 3.1 | 12.5 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 3.1 | 9.4 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 3.1 | 3.1 | GO:0060368 | regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) |
| 3.1 | 6.2 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 3.1 | 34.1 | GO:0021740 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 3.1 | 9.3 | GO:0036111 | very long-chain fatty-acyl-CoA metabolic process(GO:0036111) |
| 3.1 | 18.4 | GO:0003164 | His-Purkinje system development(GO:0003164) |
| 3.1 | 6.1 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 3.1 | 27.6 | GO:0060056 | mammary gland involution(GO:0060056) |
| 3.1 | 21.5 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
| 3.1 | 15.3 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 3.1 | 30.6 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 3.1 | 36.7 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 3.0 | 27.2 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 3.0 | 12.1 | GO:0042026 | protein refolding(GO:0042026) |
| 3.0 | 15.1 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 3.0 | 60.3 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 3.0 | 5.9 | GO:1901355 | response to rapamycin(GO:1901355) |
| 3.0 | 14.8 | GO:2001270 | regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 3.0 | 26.6 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 3.0 | 23.7 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 2.9 | 32.4 | GO:0009414 | response to water deprivation(GO:0009414) |
| 2.9 | 5.9 | GO:0035511 | oxidative DNA demethylation(GO:0035511) |
| 2.9 | 8.8 | GO:0030961 | peptidyl-arginine hydroxylation(GO:0030961) |
| 2.9 | 11.7 | GO:0051182 | coenzyme transport(GO:0051182) |
| 2.9 | 5.8 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 2.9 | 20.4 | GO:2000230 | negative regulation of pancreatic stellate cell proliferation(GO:2000230) |
| 2.9 | 34.9 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 2.9 | 20.3 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 2.9 | 2.9 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 2.9 | 34.8 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 2.9 | 14.5 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 2.9 | 11.5 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 2.9 | 8.6 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 2.9 | 14.4 | GO:0033262 | regulation of nuclear cell cycle DNA replication(GO:0033262) |
| 2.9 | 31.5 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 2.8 | 48.2 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 2.8 | 8.5 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 2.8 | 33.8 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 2.8 | 14.0 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 2.8 | 14.0 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 2.8 | 25.2 | GO:0032914 | transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 2.8 | 5.6 | GO:0032240 | MAPK import into nucleus(GO:0000189) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
| 2.8 | 25.0 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 2.8 | 30.3 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 2.8 | 27.5 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 2.7 | 19.0 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 2.7 | 40.7 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 2.7 | 13.6 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 2.7 | 10.8 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 2.7 | 16.1 | GO:0072553 | terminal button organization(GO:0072553) |
| 2.7 | 10.8 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 2.7 | 98.9 | GO:0006101 | citrate metabolic process(GO:0006101) |
| 2.7 | 10.6 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 2.7 | 13.3 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 2.7 | 23.9 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 2.6 | 227.8 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 2.6 | 26.4 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 2.6 | 28.9 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 2.6 | 26.2 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) |
| 2.6 | 5.2 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 2.6 | 31.4 | GO:0046040 | IMP metabolic process(GO:0046040) |
| 2.6 | 7.8 | GO:1903332 | regulation of protein folding(GO:1903332) negative regulation of protein folding(GO:1903333) |
| 2.6 | 39.1 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 2.6 | 12.8 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 2.6 | 7.7 | GO:0090261 | positive regulation of inclusion body assembly(GO:0090261) |
| 2.6 | 17.9 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 2.5 | 22.9 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 2.5 | 10.2 | GO:0032597 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
| 2.5 | 35.5 | GO:0060546 | negative regulation of necroptotic process(GO:0060546) |
| 2.5 | 12.7 | GO:0003069 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 2.5 | 7.6 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 2.5 | 7.6 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 2.5 | 10.1 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 2.5 | 35.2 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 2.5 | 10.0 | GO:0031440 | regulation of mRNA 3'-end processing(GO:0031440) |
| 2.5 | 54.7 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 2.5 | 44.7 | GO:0060148 | positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637) |
| 2.5 | 5.0 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
| 2.5 | 17.4 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 2.5 | 7.4 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
| 2.5 | 34.6 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
| 2.5 | 2.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 2.5 | 7.4 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 2.5 | 9.8 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 2.5 | 4.9 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 2.5 | 2.5 | GO:1903352 | ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) |
| 2.5 | 17.2 | GO:0030091 | protein repair(GO:0030091) |
| 2.4 | 21.8 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 2.4 | 26.6 | GO:0042407 | cristae formation(GO:0042407) |
| 2.4 | 31.3 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 2.4 | 2.4 | GO:0071306 | cellular response to vitamin E(GO:0071306) |
| 2.4 | 14.3 | GO:1900086 | positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086) |
| 2.4 | 2.4 | GO:1902237 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237) |
| 2.4 | 2.4 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 2.4 | 168.7 | GO:0010257 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 2.4 | 35.5 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 2.4 | 11.8 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 2.4 | 7.1 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 2.4 | 9.4 | GO:0019418 | sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) |
| 2.4 | 2.4 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 2.4 | 11.8 | GO:0015825 | L-serine transport(GO:0015825) |
| 2.3 | 77.5 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 2.3 | 14.1 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 2.3 | 7.0 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 2.3 | 7.0 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 2.3 | 2.3 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
| 2.3 | 27.9 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 2.3 | 7.0 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 2.3 | 9.3 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 2.3 | 16.1 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 2.3 | 6.9 | GO:0006565 | L-serine catabolic process(GO:0006565) |
| 2.3 | 18.3 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 2.3 | 16.0 | GO:0030638 | polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
| 2.3 | 20.5 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 2.3 | 4.5 | GO:0035358 | regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035358) |
| 2.3 | 13.5 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 2.2 | 6.7 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 2.2 | 2.2 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 2.2 | 6.7 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 2.2 | 6.7 | GO:0002439 | chronic inflammatory response to antigenic stimulus(GO:0002439) |
| 2.2 | 4.4 | GO:0051541 | elastin metabolic process(GO:0051541) |
| 2.2 | 6.6 | GO:0000912 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 2.2 | 17.5 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 2.2 | 13.1 | GO:0007296 | vitellogenesis(GO:0007296) |
| 2.2 | 35.0 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 2.2 | 4.4 | GO:0010044 | response to aluminum ion(GO:0010044) |
| 2.2 | 4.4 | GO:0045136 | development of secondary sexual characteristics(GO:0045136) |
| 2.2 | 2.2 | GO:0001916 | positive regulation of T cell mediated cytotoxicity(GO:0001916) |
| 2.2 | 6.5 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 2.2 | 4.3 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 2.2 | 8.6 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 2.2 | 8.6 | GO:0021836 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923) |
| 2.2 | 25.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 2.2 | 23.7 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 2.2 | 6.5 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 2.1 | 19.3 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
| 2.1 | 32.2 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 2.1 | 19.2 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 2.1 | 10.7 | GO:0061042 | vascular wound healing(GO:0061042) |
| 2.1 | 14.9 | GO:0051014 | actin filament severing(GO:0051014) |
| 2.1 | 21.3 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 2.1 | 4.2 | GO:0022615 | protein to membrane docking(GO:0022615) |
| 2.1 | 25.2 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 2.1 | 8.4 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 2.1 | 12.5 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 2.1 | 4.2 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 2.1 | 6.2 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 2.1 | 12.3 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 2.1 | 4.1 | GO:0072387 | flavin adenine dinucleotide metabolic process(GO:0072387) |
| 2.1 | 8.2 | GO:0000961 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 2.0 | 2.0 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 2.0 | 16.3 | GO:0006561 | proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129) |
| 2.0 | 40.5 | GO:1902254 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254) |
| 2.0 | 2.0 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
| 2.0 | 22.2 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 2.0 | 12.1 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 2.0 | 4.0 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 2.0 | 2.0 | GO:0060066 | oviduct development(GO:0060066) |
| 2.0 | 6.0 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 2.0 | 2.0 | GO:0018283 | metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283) |
| 2.0 | 4.0 | GO:1903147 | negative regulation of mitophagy(GO:1903147) |
| 2.0 | 33.9 | GO:1904707 | positive regulation of vascular smooth muscle cell proliferation(GO:1904707) |
| 2.0 | 8.0 | GO:0043173 | nucleotide salvage(GO:0043173) |
| 2.0 | 15.9 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 2.0 | 15.8 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 2.0 | 25.6 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 2.0 | 7.9 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 2.0 | 3.9 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 2.0 | 19.5 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 1.9 | 5.8 | GO:0042946 | glucoside transport(GO:0042946) |
| 1.9 | 32.7 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 1.9 | 111.5 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 1.9 | 5.7 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
| 1.9 | 11.5 | GO:0060356 | leucine import(GO:0060356) |
| 1.9 | 13.3 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 1.9 | 13.3 | GO:0032328 | alanine transport(GO:0032328) |
| 1.9 | 1.9 | GO:0031990 | mRNA export from nucleus in response to heat stress(GO:0031990) |
| 1.9 | 17.1 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 1.9 | 117.0 | GO:0031124 | mRNA 3'-end processing(GO:0031124) |
| 1.9 | 11.1 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 1.8 | 7.3 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 1.8 | 7.3 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 1.8 | 12.7 | GO:0021817 | nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) |
| 1.8 | 5.4 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 1.8 | 1.8 | GO:0038027 | apolipoprotein A-I-mediated signaling pathway(GO:0038027) |
| 1.8 | 7.2 | GO:0030472 | mitotic spindle organization in nucleus(GO:0030472) |
| 1.8 | 3.6 | GO:1904923 | regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 1.8 | 7.2 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 1.8 | 3.6 | GO:0060166 | olfactory pit development(GO:0060166) |
| 1.8 | 12.4 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 1.8 | 3.6 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 1.8 | 8.9 | GO:0015677 | copper ion import(GO:0015677) |
| 1.8 | 12.4 | GO:0001878 | response to yeast(GO:0001878) |
| 1.8 | 8.8 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 1.8 | 3.5 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 1.8 | 10.6 | GO:0072718 | response to cisplatin(GO:0072718) |
| 1.8 | 5.3 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 1.7 | 57.7 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 1.7 | 5.2 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 1.7 | 29.5 | GO:2000188 | regulation of cholesterol homeostasis(GO:2000188) |
| 1.7 | 20.8 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 1.7 | 3.5 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 1.7 | 20.7 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 1.7 | 43.0 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 1.7 | 15.5 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 1.7 | 3.4 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 1.7 | 12.0 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 1.7 | 8.6 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 1.7 | 37.6 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 1.7 | 15.4 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 1.7 | 17.0 | GO:0003149 | membranous septum morphogenesis(GO:0003149) |
| 1.7 | 13.6 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 1.7 | 1.7 | GO:0000054 | ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) |
| 1.7 | 1.7 | GO:0098917 | retrograde trans-synaptic signaling(GO:0098917) |
| 1.7 | 1.7 | GO:0044130 | negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146) |
| 1.7 | 3.4 | GO:0072019 | proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) |
| 1.7 | 15.1 | GO:0090032 | negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032) |
| 1.7 | 13.4 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 1.7 | 5.0 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
| 1.7 | 6.7 | GO:0051451 | myoblast migration(GO:0051451) |
| 1.7 | 5.0 | GO:0007538 | primary sex determination(GO:0007538) |
| 1.7 | 5.0 | GO:0036093 | male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093) |
| 1.7 | 8.3 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 1.7 | 5.0 | GO:0072708 | response to sorbitol(GO:0072708) cellular response to sorbitol(GO:0072709) |
| 1.7 | 5.0 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 1.6 | 1.6 | GO:0070142 | synaptic vesicle budding(GO:0070142) |
| 1.6 | 17.9 | GO:0046149 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 1.6 | 102.0 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 1.6 | 8.0 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 1.6 | 4.8 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
| 1.6 | 9.5 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 1.6 | 37.8 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 1.6 | 4.7 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
| 1.6 | 6.2 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 1.6 | 3.1 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
| 1.6 | 17.1 | GO:2001286 | regulation of caveolin-mediated endocytosis(GO:2001286) positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 1.6 | 6.2 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 1.6 | 4.7 | GO:1901804 | glucosylceramide catabolic process(GO:0006680) positive regulation of macromitophagy(GO:1901526) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 1.5 | 6.2 | GO:1904504 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
| 1.5 | 4.6 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 1.5 | 13.7 | GO:0006907 | pinocytosis(GO:0006907) |
| 1.5 | 4.6 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 1.5 | 9.1 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 1.5 | 15.2 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 1.5 | 3.0 | GO:1904751 | regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751) |
| 1.5 | 3.0 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 1.5 | 16.5 | GO:0071340 | skeletal muscle acetylcholine-gated channel clustering(GO:0071340) |
| 1.5 | 3.0 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 1.5 | 16.2 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 1.5 | 48.3 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 1.5 | 2.9 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
| 1.4 | 4.3 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 1.4 | 1.4 | GO:0007412 | axon target recognition(GO:0007412) |
| 1.4 | 12.9 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 1.4 | 8.6 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 1.4 | 18.6 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 1.4 | 15.7 | GO:0099515 | vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515) |
| 1.4 | 2.8 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 1.4 | 8.5 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 1.4 | 22.1 | GO:0031639 | plasminogen activation(GO:0031639) |
| 1.4 | 8.3 | GO:2000615 | histone H3-K9 acetylation(GO:0043970) regulation of histone H3-K9 acetylation(GO:2000615) |
| 1.4 | 16.6 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 1.4 | 2.7 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
| 1.4 | 6.9 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
| 1.4 | 28.7 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
| 1.4 | 1.4 | GO:0061443 | endocardial cushion cell differentiation(GO:0061443) |
| 1.4 | 4.1 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 1.4 | 28.4 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 1.4 | 2.7 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) |
| 1.3 | 12.1 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 1.3 | 4.0 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
| 1.3 | 4.0 | GO:2000521 | regulation of immunological synapse formation(GO:2000520) negative regulation of immunological synapse formation(GO:2000521) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189) |
| 1.3 | 9.3 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 1.3 | 6.6 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) |
| 1.3 | 82.1 | GO:0006901 | vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 1.3 | 1.3 | GO:0016240 | autophagosome docking(GO:0016240) |
| 1.3 | 24.8 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 1.3 | 11.7 | GO:0071926 | endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124) |
| 1.3 | 6.5 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 1.3 | 18.2 | GO:0050832 | defense response to fungus(GO:0050832) |
| 1.3 | 1.3 | GO:0036301 | macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) regulation of macrophage colony-stimulating factor production(GO:1901256) positive regulation of macrophage colony-stimulating factor production(GO:1901258) |
| 1.3 | 3.8 | GO:0001807 | regulation of type IV hypersensitivity(GO:0001807) negative regulation of binding of sperm to zona pellucida(GO:2000360) |
| 1.3 | 1.3 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 1.3 | 12.7 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 1.3 | 13.9 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 1.2 | 8.7 | GO:0036109 | alpha-linolenic acid metabolic process(GO:0036109) |
| 1.2 | 6.2 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 1.2 | 3.7 | GO:0045897 | positive regulation of transcription during mitosis(GO:0045897) |
| 1.2 | 6.2 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 1.2 | 22.0 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 1.2 | 26.8 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
| 1.2 | 3.6 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 1.2 | 7.3 | GO:0043316 | cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435) |
| 1.2 | 12.0 | GO:0045008 | depyrimidination(GO:0045008) |
| 1.2 | 2.4 | GO:0040031 | snRNA modification(GO:0040031) |
| 1.2 | 3.6 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 1.2 | 15.4 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 1.2 | 4.7 | GO:0051410 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
| 1.2 | 9.4 | GO:0051601 | exocyst localization(GO:0051601) |
| 1.2 | 12.8 | GO:0006903 | vesicle targeting(GO:0006903) |
| 1.2 | 1.2 | GO:0033690 | positive regulation of osteoblast proliferation(GO:0033690) |
| 1.2 | 55.4 | GO:0042267 | natural killer cell mediated cytotoxicity(GO:0042267) |
| 1.2 | 17.3 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 1.2 | 39.1 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
| 1.2 | 8.1 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 1.1 | 1.1 | GO:0010041 | response to iron(III) ion(GO:0010041) |
| 1.1 | 9.1 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 1.1 | 3.4 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 1.1 | 4.5 | GO:0006591 | ornithine metabolic process(GO:0006591) |
| 1.1 | 52.2 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 1.1 | 87.5 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 1.1 | 9.0 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 1.1 | 8.9 | GO:0034629 | cellular protein complex localization(GO:0034629) |
| 1.1 | 4.4 | GO:0010193 | response to ozone(GO:0010193) |
| 1.1 | 4.4 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 1.1 | 1.1 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
| 1.1 | 1.1 | GO:0035915 | pore formation in membrane of other organism(GO:0035915) membrane disruption in other organism(GO:0051673) |
| 1.1 | 6.5 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 1.1 | 2.2 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 1.1 | 1.1 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 1.1 | 2.2 | GO:0072143 | renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) |
| 1.1 | 12.9 | GO:0021840 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
| 1.1 | 4.3 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 1.1 | 6.3 | GO:0051573 | negative regulation of histone H3-K9 methylation(GO:0051573) |
| 1.0 | 8.4 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 1.0 | 6.3 | GO:0045408 | regulation of interleukin-6 biosynthetic process(GO:0045408) |
| 1.0 | 1.0 | GO:0060585 | regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
| 1.0 | 2.1 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 1.0 | 1.0 | GO:0035973 | aggrephagy(GO:0035973) |
| 1.0 | 5.2 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 1.0 | 4.1 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 1.0 | 112.9 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 1.0 | 18.2 | GO:0019835 | cytolysis(GO:0019835) |
| 1.0 | 5.1 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 1.0 | 4.0 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
| 1.0 | 32.0 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 1.0 | 2.0 | GO:0018916 | nitrobenzene metabolic process(GO:0018916) |
| 1.0 | 2.9 | GO:0033385 | geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) |
| 1.0 | 20.4 | GO:0031290 | retinal ganglion cell axon guidance(GO:0031290) |
| 1.0 | 11.7 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 1.0 | 5.8 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 1.0 | 2.9 | GO:0032808 | lacrimal gland development(GO:0032808) |
| 1.0 | 3.8 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.9 | 18.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.9 | 4.6 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 0.9 | 2.7 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 0.9 | 13.7 | GO:0006283 | transcription-coupled nucleotide-excision repair(GO:0006283) |
| 0.9 | 13.6 | GO:0009201 | ribonucleoside triphosphate biosynthetic process(GO:0009201) |
| 0.9 | 1.8 | GO:0051352 | negative regulation of ligase activity(GO:0051352) |
| 0.9 | 9.1 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.9 | 1.8 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.9 | 1.8 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 0.9 | 2.7 | GO:0048840 | otolith development(GO:0048840) |
| 0.9 | 6.3 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.9 | 2.7 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.9 | 2.7 | GO:0010455 | positive regulation of cell fate commitment(GO:0010455) |
| 0.9 | 5.3 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.9 | 4.4 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.9 | 10.4 | GO:0007031 | peroxisome organization(GO:0007031) |
| 0.9 | 7.8 | GO:0046689 | response to mercury ion(GO:0046689) |
| 0.9 | 1.7 | GO:0002730 | regulation of dendritic cell cytokine production(GO:0002730) |
| 0.9 | 8.7 | GO:0048853 | forebrain morphogenesis(GO:0048853) |
| 0.9 | 16.4 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.9 | 6.9 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 0.9 | 2.6 | GO:0000472 | endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471) |
| 0.9 | 3.4 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 0.9 | 10.2 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
| 0.9 | 1.7 | GO:0061739 | protein lipidation involved in autophagosome assembly(GO:0061739) |
| 0.9 | 17.9 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.8 | 5.1 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
| 0.8 | 1.7 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.8 | 7.6 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.8 | 8.4 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.8 | 5.8 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.8 | 1.6 | GO:0098502 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) DNA dephosphorylation(GO:0098502) |
| 0.8 | 5.8 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.8 | 4.9 | GO:0000212 | meiotic spindle organization(GO:0000212) |
| 0.8 | 2.4 | GO:1903565 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 0.8 | 1.6 | GO:0051389 | inactivation of MAPKK activity(GO:0051389) |
| 0.8 | 10.6 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
| 0.8 | 2.4 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 0.8 | 17.8 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.8 | 11.3 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.8 | 79.2 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.8 | 4.8 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.8 | 3.9 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.8 | 15.0 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 0.8 | 22.6 | GO:0002063 | chondrocyte development(GO:0002063) |
| 0.8 | 31.0 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.8 | 9.3 | GO:2000484 | positive regulation of interleukin-8 secretion(GO:2000484) |
| 0.8 | 1.5 | GO:0006563 | L-serine metabolic process(GO:0006563) |
| 0.8 | 2.3 | GO:0060988 | lipid tube assembly(GO:0060988) |
| 0.8 | 32.0 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.8 | 2.3 | GO:2000620 | innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.8 | 71.8 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.8 | 4.5 | GO:0034134 | toll-like receptor 2 signaling pathway(GO:0034134) |
| 0.8 | 3.8 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) |
| 0.8 | 6.8 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.8 | 9.0 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.7 | 36.1 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.7 | 5.1 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.7 | 3.7 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.7 | 71.4 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.7 | 10.9 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.7 | 2.9 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.7 | 27.5 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.7 | 0.7 | GO:0042984 | amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984) |
| 0.7 | 0.7 | GO:0001834 | trophectodermal cell proliferation(GO:0001834) |
| 0.7 | 2.1 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.7 | 17.7 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.7 | 7.8 | GO:2000009 | negative regulation of protein localization to cell surface(GO:2000009) |
| 0.7 | 2.1 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.7 | 6.9 | GO:0042401 | cellular biogenic amine biosynthetic process(GO:0042401) |
| 0.7 | 2.7 | GO:0061051 | positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) |
| 0.7 | 1.4 | GO:1900016 | negative regulation of cytokine production involved in inflammatory response(GO:1900016) |
| 0.7 | 1.3 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.7 | 22.8 | GO:1901224 | positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
| 0.7 | 2.0 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.7 | 12.7 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.7 | 7.3 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.7 | 5.9 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.7 | 1.3 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.7 | 0.7 | GO:0022605 | oogenesis stage(GO:0022605) |
| 0.6 | 16.1 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.6 | 9.5 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.6 | 5.0 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.6 | 8.8 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654) |
| 0.6 | 2.5 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 0.6 | 3.1 | GO:0042374 | phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662) |
| 0.6 | 2.5 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.6 | 5.0 | GO:0001967 | suckling behavior(GO:0001967) |
| 0.6 | 2.5 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.6 | 25.8 | GO:0044364 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.6 | 0.6 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 0.6 | 0.6 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.6 | 1.8 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.6 | 16.7 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.6 | 16.0 | GO:0061462 | protein localization to lysosome(GO:0061462) |
| 0.6 | 2.4 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.6 | 4.1 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.6 | 10.0 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.6 | 4.1 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.6 | 2.9 | GO:0045006 | DNA deamination(GO:0045006) DNA cytosine deamination(GO:0070383) |
| 0.6 | 14.0 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
| 0.6 | 2.3 | GO:0034201 | response to oleic acid(GO:0034201) |
| 0.6 | 2.9 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.6 | 4.0 | GO:1902956 | regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) |
| 0.6 | 13.4 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.6 | 5.0 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.6 | 3.3 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.5 | 2.2 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.5 | 7.1 | GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) |
| 0.5 | 2.2 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.5 | 3.3 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.5 | 2.7 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.5 | 0.5 | GO:1900127 | positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 0.5 | 6.4 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.5 | 2.6 | GO:0055005 | ventricular cardiac myofibril assembly(GO:0055005) |
| 0.5 | 2.1 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
| 0.5 | 8.7 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.5 | 4.6 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.5 | 3.0 | GO:0006051 | mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051) |
| 0.5 | 3.0 | GO:0007567 | parturition(GO:0007567) |
| 0.5 | 3.0 | GO:0070200 | establishment of protein localization to telomere(GO:0070200) |
| 0.5 | 8.9 | GO:0046039 | GTP metabolic process(GO:0046039) |
| 0.5 | 5.3 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.5 | 1.9 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.5 | 2.9 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.5 | 1.4 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.5 | 1.4 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.5 | 0.9 | GO:0019853 | L-ascorbic acid biosynthetic process(GO:0019853) |
| 0.5 | 3.8 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.5 | 0.9 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 0.5 | 0.9 | GO:0061643 | chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643) |
| 0.5 | 1.9 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.5 | 1.4 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.5 | 1.8 | GO:0032506 | cytokinetic process(GO:0032506) |
| 0.5 | 3.2 | GO:0007379 | segment specification(GO:0007379) |
| 0.5 | 2.7 | GO:1901626 | regulation of postsynaptic membrane organization(GO:1901626) |
| 0.5 | 5.4 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.4 | 2.2 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.4 | 0.9 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
| 0.4 | 2.1 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.4 | 4.3 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 0.4 | 1.7 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.4 | 5.5 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.4 | 1.3 | GO:0060278 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.4 | 0.8 | GO:0097278 | complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) |
| 0.4 | 3.3 | GO:0035581 | sequestering of extracellular ligand from receptor(GO:0035581) |
| 0.4 | 22.5 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.4 | 0.4 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.4 | 12.6 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.4 | 9.7 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.4 | 12.1 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.4 | 4.4 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.4 | 1.2 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.4 | 2.4 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.4 | 2.0 | GO:0042534 | tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534) |
| 0.4 | 6.2 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.4 | 1.5 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
| 0.4 | 4.0 | GO:0099630 | postsynaptic neurotransmitter receptor cycle(GO:0099630) |
| 0.4 | 2.2 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.4 | 1.8 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 0.4 | 1.8 | GO:0042747 | circadian sleep/wake cycle, REM sleep(GO:0042747) |
| 0.4 | 4.6 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
| 0.4 | 1.8 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.4 | 3.2 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.3 | 2.8 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.3 | 2.1 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 0.3 | 8.0 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.3 | 2.1 | GO:0001712 | ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712) |
| 0.3 | 1.7 | GO:0009070 | serine family amino acid biosynthetic process(GO:0009070) |
| 0.3 | 1.7 | GO:0010663 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.3 | 1.0 | GO:1901534 | positive regulation of hematopoietic progenitor cell differentiation(GO:1901534) |
| 0.3 | 1.0 | GO:0015809 | arginine transport(GO:0015809) |
| 0.3 | 2.3 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 0.3 | 0.7 | GO:0006983 | ER overload response(GO:0006983) |
| 0.3 | 1.3 | GO:1904293 | negative regulation of ERAD pathway(GO:1904293) |
| 0.3 | 2.2 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.3 | 0.3 | GO:0007028 | cytoplasm organization(GO:0007028) |
| 0.3 | 1.7 | GO:0032096 | negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099) |
| 0.3 | 0.6 | GO:0035795 | negative regulation of mitochondrial membrane permeability(GO:0035795) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.3 | 1.1 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.3 | 2.0 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.3 | 8.1 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.3 | 1.1 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.3 | 6.3 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.3 | 7.7 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.3 | 82.7 | GO:0043312 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
| 0.3 | 5.3 | GO:0002437 | inflammatory response to antigenic stimulus(GO:0002437) |
| 0.3 | 1.5 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.2 | 2.7 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.2 | 2.2 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.2 | 0.5 | GO:0009138 | pyrimidine nucleoside diphosphate metabolic process(GO:0009138) |
| 0.2 | 3.6 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.2 | 0.5 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.2 | 2.6 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.2 | 0.9 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.2 | 0.9 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.2 | 0.2 | GO:0031943 | regulation of glucocorticoid metabolic process(GO:0031943) |
| 0.2 | 1.0 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
| 0.2 | 1.6 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.2 | 0.6 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
| 0.2 | 2.1 | GO:0097286 | iron ion import(GO:0097286) |
| 0.2 | 1.5 | GO:0035584 | calcium-mediated signaling using intracellular calcium source(GO:0035584) |
| 0.2 | 3.1 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
| 0.2 | 1.1 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.2 | 2.5 | GO:0048490 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.2 | 9.7 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.2 | 0.5 | GO:0042369 | vitamin D catabolic process(GO:0042369) |
| 0.2 | 1.2 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
| 0.2 | 3.8 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.2 | 0.5 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 0.2 | 0.2 | GO:0016199 | axon midline choice point recognition(GO:0016199) |
| 0.2 | 3.0 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.2 | 3.7 | GO:0006414 | translational elongation(GO:0006414) |
| 0.2 | 3.7 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.2 | 3.7 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.2 | 0.9 | GO:0051958 | methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838) |
| 0.1 | 1.0 | GO:0050858 | negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) |
| 0.1 | 0.5 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) |
| 0.1 | 0.3 | GO:0010835 | regulation of protein ADP-ribosylation(GO:0010835) |
| 0.1 | 0.5 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.1 | 0.3 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.1 | 0.2 | GO:1990822 | basic amino acid transmembrane transport(GO:1990822) |
| 0.1 | 0.2 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.1 | 0.6 | GO:0050932 | regulation of pigment cell differentiation(GO:0050932) |
| 0.1 | 0.8 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.1 | 0.3 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 0.1 | 0.2 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.1 | 0.1 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.0 | 1.3 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.5 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.0 | 0.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.0 | 0.2 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.4 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.0 | 0.0 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 0.0 | 0.1 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 23.2 | 23.2 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 18.9 | 94.7 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 18.7 | 74.8 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 18.1 | 108.3 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 16.9 | 50.7 | GO:0036284 | tubulobulbar complex(GO:0036284) |
| 16.9 | 84.5 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 15.2 | 60.6 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 14.8 | 162.8 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 14.2 | 156.3 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 13.5 | 80.7 | GO:0097422 | tubular endosome(GO:0097422) |
| 13.4 | 53.7 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 13.1 | 52.5 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
| 12.5 | 62.4 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 12.0 | 83.7 | GO:0016589 | NURF complex(GO:0016589) |
| 11.2 | 112.4 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 10.6 | 53.2 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 10.5 | 52.4 | GO:0031523 | Myb complex(GO:0031523) |
| 10.4 | 41.4 | GO:0071817 | MMXD complex(GO:0071817) |
| 10.0 | 60.3 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 10.0 | 50.1 | GO:0033503 | HULC complex(GO:0033503) |
| 10.0 | 70.0 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 9.9 | 109.0 | GO:0005955 | calcineurin complex(GO:0005955) |
| 9.7 | 9.7 | GO:0089701 | U2AF(GO:0089701) |
| 9.5 | 47.6 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 9.5 | 151.4 | GO:0005642 | annulate lamellae(GO:0005642) |
| 9.4 | 84.2 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 9.3 | 92.5 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 9.1 | 54.7 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 9.0 | 81.2 | GO:0042382 | paraspeckles(GO:0042382) |
| 9.0 | 72.2 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 8.9 | 35.4 | GO:0071942 | XPC complex(GO:0071942) |
| 8.8 | 227.7 | GO:0005916 | fascia adherens(GO:0005916) |
| 8.6 | 146.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 8.6 | 42.9 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 8.1 | 48.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 8.1 | 40.6 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 8.1 | 64.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 7.9 | 31.6 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 7.7 | 115.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 7.6 | 15.2 | GO:1990423 | RZZ complex(GO:1990423) |
| 7.5 | 15.0 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 7.4 | 184.4 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 7.3 | 7.3 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 7.3 | 65.4 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 7.2 | 50.4 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 7.1 | 28.3 | GO:0048179 | activin receptor complex(GO:0048179) |
| 7.1 | 98.9 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 7.1 | 84.8 | GO:0090543 | Flemming body(GO:0090543) |
| 7.0 | 28.1 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 7.0 | 27.9 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 6.9 | 54.9 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 6.8 | 13.7 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 6.8 | 94.8 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 6.8 | 74.5 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 6.8 | 74.4 | GO:0016600 | flotillin complex(GO:0016600) |
| 6.8 | 67.6 | GO:0097255 | R2TP complex(GO:0097255) |
| 6.7 | 13.4 | GO:0008623 | CHRAC(GO:0008623) |
| 6.6 | 26.5 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 6.4 | 103.0 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 6.3 | 31.4 | GO:0044094 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 6.2 | 112.1 | GO:0032433 | filopodium tip(GO:0032433) |
| 6.2 | 18.6 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 5.9 | 35.7 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 5.9 | 164.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 5.8 | 46.4 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 5.7 | 40.2 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 5.7 | 68.1 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 5.6 | 33.5 | GO:0071797 | LUBAC complex(GO:0071797) |
| 5.6 | 88.8 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 5.5 | 33.3 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 5.5 | 55.0 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
| 5.5 | 22.0 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
| 5.5 | 49.2 | GO:0070938 | contractile ring(GO:0070938) |
| 5.5 | 60.0 | GO:0070449 | elongin complex(GO:0070449) |
| 5.4 | 59.5 | GO:0005638 | lamin filament(GO:0005638) |
| 5.3 | 21.3 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 5.3 | 37.2 | GO:0071664 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) |
| 5.3 | 15.8 | GO:0043259 | laminin-10 complex(GO:0043259) |
| 5.3 | 36.9 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 5.3 | 26.4 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 5.1 | 81.8 | GO:0097470 | ribbon synapse(GO:0097470) |
| 5.1 | 132.5 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 5.1 | 75.9 | GO:0034709 | methylosome(GO:0034709) |
| 5.1 | 5.1 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 5.0 | 35.3 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 5.0 | 140.7 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 4.9 | 19.7 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 4.9 | 39.3 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 4.9 | 24.4 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 4.9 | 78.1 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 4.8 | 77.2 | GO:0033179 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 4.7 | 32.8 | GO:0032021 | NELF complex(GO:0032021) |
| 4.7 | 14.1 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 4.6 | 37.2 | GO:0000796 | condensin complex(GO:0000796) |
| 4.6 | 4.6 | GO:0031332 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 4.5 | 45.5 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 4.5 | 22.5 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 4.5 | 71.3 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 4.4 | 97.7 | GO:0030056 | hemidesmosome(GO:0030056) |
| 4.4 | 57.3 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 4.4 | 21.9 | GO:0005749 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 4.3 | 95.7 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 4.3 | 73.6 | GO:0016469 | proton-transporting two-sector ATPase complex(GO:0016469) |
| 4.3 | 17.2 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 4.2 | 33.9 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 4.2 | 63.6 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 4.2 | 25.3 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 4.2 | 12.6 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 4.2 | 12.6 | GO:0097441 | basilar dendrite(GO:0097441) |
| 4.2 | 29.3 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 4.2 | 12.5 | GO:0030677 | ribonuclease P complex(GO:0030677) |
| 4.2 | 50.1 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 4.2 | 299.1 | GO:0005876 | spindle microtubule(GO:0005876) |
| 4.1 | 24.5 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 4.1 | 77.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 4.0 | 24.2 | GO:0061617 | MICOS complex(GO:0061617) |
| 4.0 | 28.2 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 4.0 | 32.0 | GO:0034385 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 4.0 | 4.0 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 4.0 | 43.6 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 3.9 | 15.8 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 3.9 | 23.6 | GO:0001939 | female pronucleus(GO:0001939) |
| 3.9 | 3.9 | GO:0044393 | microspike(GO:0044393) |
| 3.8 | 3.8 | GO:0034665 | integrin alpha1-beta1 complex(GO:0034665) |
| 3.8 | 56.3 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 3.7 | 26.1 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 3.7 | 11.2 | GO:1990917 | sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917) |
| 3.7 | 77.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 3.7 | 70.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 3.7 | 25.8 | GO:0031415 | NatA complex(GO:0031415) |
| 3.7 | 40.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 3.7 | 494.1 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 3.6 | 7.3 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 3.6 | 36.3 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 3.6 | 10.9 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 3.6 | 42.9 | GO:0005869 | dynactin complex(GO:0005869) |
| 3.5 | 10.5 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 3.4 | 20.6 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 3.4 | 40.9 | GO:0031209 | SCAR complex(GO:0031209) |
| 3.4 | 3.4 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 3.4 | 37.0 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 3.4 | 10.1 | GO:0097452 | GAIT complex(GO:0097452) |
| 3.3 | 16.7 | GO:0032449 | CBM complex(GO:0032449) |
| 3.3 | 16.7 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 3.3 | 6.7 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 3.3 | 19.6 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 3.2 | 3.2 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 3.2 | 357.5 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 3.2 | 532.3 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 3.2 | 9.6 | GO:0072563 | endothelial microparticle(GO:0072563) |
| 3.2 | 35.2 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 3.2 | 9.6 | GO:0018444 | translation release factor complex(GO:0018444) |
| 3.2 | 15.9 | GO:0043291 | RAVE complex(GO:0043291) |
| 3.2 | 19.0 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 3.1 | 28.0 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 3.1 | 6.2 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 3.1 | 12.3 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 3.1 | 61.1 | GO:0031143 | pseudopodium(GO:0031143) |
| 3.0 | 42.0 | GO:0005685 | U1 snRNP(GO:0005685) |
| 3.0 | 6.0 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 3.0 | 11.9 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 3.0 | 26.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 3.0 | 68.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 3.0 | 11.8 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 2.9 | 8.8 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 2.9 | 66.1 | GO:0046930 | pore complex(GO:0046930) |
| 2.9 | 45.9 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 2.8 | 113.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 2.8 | 8.4 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 2.8 | 11.2 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 2.8 | 8.4 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 2.8 | 2.8 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 2.7 | 90.6 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 2.7 | 16.4 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 2.7 | 8.2 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 2.7 | 19.1 | GO:0005688 | U6 snRNP(GO:0005688) |
| 2.7 | 35.2 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 2.7 | 5.3 | GO:1903349 | omegasome membrane(GO:1903349) |
| 2.7 | 61.3 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 2.6 | 13.2 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 2.6 | 86.6 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 2.6 | 1529.0 | GO:0005925 | focal adhesion(GO:0005925) |
| 2.6 | 13.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 2.6 | 13.0 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 2.6 | 10.3 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 2.6 | 10.2 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 2.5 | 10.0 | GO:0044308 | axonal spine(GO:0044308) |
| 2.5 | 7.4 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 2.4 | 17.1 | GO:0016272 | prefoldin complex(GO:0016272) |
| 2.3 | 7.0 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 2.3 | 7.0 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 2.3 | 184.4 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 2.3 | 21.0 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 2.3 | 34.9 | GO:0097346 | Swr1 complex(GO:0000812) INO80-type complex(GO:0097346) |
| 2.3 | 32.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 2.3 | 20.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 2.3 | 13.6 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 2.3 | 11.3 | GO:0032044 | DSIF complex(GO:0032044) |
| 2.3 | 38.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 2.2 | 33.7 | GO:0000346 | transcription export complex(GO:0000346) |
| 2.2 | 18.0 | GO:0070852 | cell body fiber(GO:0070852) |
| 2.2 | 11.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 2.2 | 2.2 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 2.2 | 11.1 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 2.2 | 44.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 2.2 | 64.2 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 2.2 | 19.8 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 2.2 | 24.1 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 2.1 | 10.7 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 2.1 | 33.5 | GO:0035267 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 2.0 | 26.5 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 2.0 | 36.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 2.0 | 44.1 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 2.0 | 44.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 1.9 | 38.9 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 1.9 | 75.6 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 1.9 | 70.8 | GO:0043034 | costamere(GO:0043034) |
| 1.9 | 168.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 1.9 | 5.6 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 1.9 | 9.3 | GO:0001739 | sex chromatin(GO:0001739) |
| 1.9 | 18.5 | GO:0097413 | Lewy body(GO:0097413) |
| 1.8 | 62.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 1.8 | 14.6 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 1.8 | 18.1 | GO:0032059 | bleb(GO:0032059) |
| 1.8 | 118.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 1.8 | 154.3 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 1.8 | 17.6 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 1.7 | 7.0 | GO:0071564 | npBAF complex(GO:0071564) |
| 1.7 | 102.8 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 1.7 | 20.9 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 1.7 | 6.8 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 1.7 | 16.6 | GO:0005839 | proteasome core complex(GO:0005839) |
| 1.6 | 17.6 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 1.6 | 8.0 | GO:0045180 | basal cortex(GO:0045180) |
| 1.6 | 17.4 | GO:0030904 | retromer complex(GO:0030904) |
| 1.6 | 1.6 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 1.6 | 1.6 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 1.6 | 31.2 | GO:0000502 | proteasome complex(GO:0000502) |
| 1.6 | 15.6 | GO:0070552 | BRISC complex(GO:0070552) |
| 1.6 | 99.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 1.5 | 45.4 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 1.5 | 6.0 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 1.5 | 16.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 1.5 | 13.1 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 1.4 | 7.1 | GO:0008274 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 1.4 | 4.2 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 1.4 | 2.7 | GO:0000805 | X chromosome(GO:0000805) |
| 1.4 | 4.1 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 1.4 | 2.7 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 1.4 | 10.8 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 1.3 | 21.1 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 1.3 | 40.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 1.3 | 97.1 | GO:0005811 | lipid particle(GO:0005811) |
| 1.3 | 13.1 | GO:0032592 | integral component of mitochondrial membrane(GO:0032592) |
| 1.3 | 73.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 1.3 | 3.8 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 1.3 | 5.1 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 1.3 | 12.6 | GO:0061574 | ASAP complex(GO:0061574) |
| 1.3 | 3.8 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 1.2 | 12.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 1.2 | 63.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 1.2 | 9.6 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 1.2 | 2.4 | GO:0098573 | intrinsic component of mitochondrial membrane(GO:0098573) |
| 1.2 | 3.6 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 1.2 | 7.0 | GO:0071203 | WASH complex(GO:0071203) |
| 1.2 | 3150.2 | GO:0070062 | extracellular exosome(GO:0070062) |
| 1.1 | 3.4 | GO:0016938 | kinesin I complex(GO:0016938) |
| 1.1 | 1.1 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 1.1 | 6.6 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 1.1 | 9.8 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 1.1 | 2.2 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 1.1 | 3.2 | GO:1990393 | 3M complex(GO:1990393) |
| 1.0 | 26.1 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 1.0 | 37.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 1.0 | 6.9 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 1.0 | 11.8 | GO:0030008 | TRAPP complex(GO:0030008) |
| 1.0 | 1.9 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 1.0 | 16.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 1.0 | 2.9 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.9 | 7.2 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.9 | 43.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.9 | 2.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.9 | 25.1 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.9 | 0.9 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.8 | 22.6 | GO:0005921 | gap junction(GO:0005921) |
| 0.8 | 6.6 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.8 | 21.1 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.8 | 3.2 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.8 | 7.0 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.8 | 2.3 | GO:0060987 | lipid tube(GO:0060987) |
| 0.8 | 6.8 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.7 | 2.9 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.7 | 4.4 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.7 | 26.8 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.7 | 36.0 | GO:0005903 | brush border(GO:0005903) |
| 0.7 | 10.9 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.7 | 2.7 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
| 0.7 | 5.3 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.6 | 6.9 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.6 | 3.0 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.6 | 1.8 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.6 | 5.9 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.6 | 1.7 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.6 | 4.5 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.6 | 7.8 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.5 | 4.8 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.5 | 2.0 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.5 | 10.5 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.5 | 9.5 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.5 | 10.1 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
| 0.4 | 1.3 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.4 | 64.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.3 | 7.9 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.3 | 28.6 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.3 | 4.7 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.3 | 2.0 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.3 | 1.3 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.3 | 0.3 | GO:0071920 | cleavage body(GO:0071920) |
| 0.3 | 12.7 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.3 | 1.7 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.3 | 11.6 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.3 | 3.9 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.3 | 3.4 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.3 | 2.7 | GO:0032982 | myosin filament(GO:0032982) |
| 0.3 | 1.3 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.2 | 1.2 | GO:0043196 | varicosity(GO:0043196) |
| 0.2 | 2.6 | GO:0032039 | integrator complex(GO:0032039) |
| 0.2 | 0.6 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.2 | 15.8 | GO:0000922 | spindle pole(GO:0000922) |
| 0.2 | 1.4 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.2 | 1.1 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.2 | 1.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 1.4 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 0.7 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.1 | 1.9 | GO:0038201 | TOR complex(GO:0038201) |
| 0.1 | 0.6 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.1 | 8.0 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.1 | 0.9 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.1 | 0.9 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.1 | 0.7 | GO:0032797 | SMN complex(GO:0032797) |
| 0.1 | 6.2 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 2.0 | GO:0000779 | condensed chromosome, centromeric region(GO:0000779) |
| 0.0 | 1.8 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.8 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.5 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 22.7 | 90.8 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 22.1 | 110.6 | GO:0047280 | nicotinamide phosphoribosyltransferase activity(GO:0047280) |
| 22.1 | 66.3 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 21.9 | 65.8 | GO:0015137 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 20.5 | 61.4 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 19.1 | 134.0 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 16.6 | 49.7 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 16.1 | 112.9 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 15.5 | 46.5 | GO:0080023 | 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023) |
| 14.9 | 59.7 | GO:1904408 | dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408) |
| 14.1 | 42.2 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 14.0 | 56.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 13.9 | 83.6 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 13.9 | 55.5 | GO:0047676 | arachidonate-CoA ligase activity(GO:0047676) |
| 13.7 | 41.1 | GO:0047315 | kynurenine-glyoxylate transaminase activity(GO:0047315) |
| 13.5 | 121.2 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 13.3 | 53.1 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 13.0 | 90.8 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 12.9 | 38.7 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 12.8 | 38.5 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 12.6 | 37.8 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 12.6 | 50.4 | GO:0004001 | adenosine kinase activity(GO:0004001) |
| 12.6 | 75.5 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 12.6 | 50.3 | GO:0004360 | glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) |
| 12.5 | 49.9 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 12.2 | 36.6 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
| 12.0 | 36.1 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 11.7 | 46.6 | GO:0051748 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 11.4 | 102.4 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 11.3 | 56.5 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 11.0 | 32.9 | GO:0004639 | phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639) |
| 10.8 | 43.4 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 10.8 | 32.3 | GO:0048030 | disaccharide binding(GO:0048030) |
| 10.6 | 53.0 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
| 10.5 | 52.6 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 10.5 | 31.5 | GO:0016822 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 10.5 | 73.2 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 10.4 | 155.9 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 10.2 | 50.9 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 9.7 | 135.4 | GO:0031386 | protein tag(GO:0031386) |
| 9.7 | 38.6 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 9.4 | 37.5 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 9.4 | 74.9 | GO:0015288 | porin activity(GO:0015288) |
| 9.4 | 65.5 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 9.3 | 111.2 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 9.2 | 92.3 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 9.2 | 83.1 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 9.1 | 27.4 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 9.0 | 35.9 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 9.0 | 53.7 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 8.9 | 89.4 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 8.8 | 412.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 8.7 | 26.1 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 8.6 | 34.2 | GO:0102007 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 8.5 | 25.6 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 8.3 | 8.3 | GO:0016672 | oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) |
| 8.2 | 24.6 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 8.2 | 229.2 | GO:0017166 | vinculin binding(GO:0017166) |
| 8.1 | 64.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 8.0 | 24.1 | GO:0003978 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 7.9 | 39.4 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 7.8 | 54.9 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 7.8 | 54.3 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 7.8 | 23.3 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 7.7 | 53.7 | GO:0004459 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 7.5 | 7.5 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 7.4 | 22.2 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 7.2 | 21.6 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 7.1 | 28.4 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 7.0 | 27.9 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 7.0 | 27.9 | GO:0061650 | ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 6.9 | 34.7 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 6.9 | 48.4 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 6.8 | 54.5 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 6.7 | 33.3 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
| 6.7 | 33.3 | GO:0016936 | galactoside binding(GO:0016936) |
| 6.6 | 26.5 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 6.6 | 19.9 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 6.6 | 39.7 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 6.5 | 32.4 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 6.4 | 103.0 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 6.4 | 32.1 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 6.3 | 19.0 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 6.2 | 24.8 | GO:0004146 | dihydrofolate reductase activity(GO:0004146) |
| 6.2 | 49.4 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 6.2 | 135.9 | GO:0008494 | translation activator activity(GO:0008494) |
| 6.2 | 179.2 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 6.1 | 6.1 | GO:1903135 | cupric ion binding(GO:1903135) |
| 6.1 | 79.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 6.1 | 18.3 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 6.1 | 18.2 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
| 6.1 | 60.6 | GO:0042731 | PH domain binding(GO:0042731) |
| 5.9 | 35.5 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 5.9 | 35.3 | GO:0004310 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 5.8 | 40.7 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 5.7 | 45.4 | GO:0030911 | TPR domain binding(GO:0030911) |
| 5.7 | 62.5 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 5.7 | 180.9 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 5.6 | 28.1 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 5.6 | 50.4 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 5.6 | 27.9 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 5.5 | 16.6 | GO:0002054 | nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060) |
| 5.5 | 22.0 | GO:0005471 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 5.5 | 11.0 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 5.4 | 124.5 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 5.4 | 432.5 | GO:0019003 | GDP binding(GO:0019003) |
| 5.3 | 16.0 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 5.3 | 47.6 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 5.3 | 68.3 | GO:0004549 | tRNA-specific ribonuclease activity(GO:0004549) |
| 5.2 | 146.5 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 5.2 | 47.0 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 5.2 | 10.3 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 5.1 | 5.1 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 5.1 | 15.2 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
| 5.1 | 20.2 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 5.1 | 20.2 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 5.0 | 50.2 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 5.0 | 30.0 | GO:0034046 | poly(G) binding(GO:0034046) |
| 4.9 | 9.8 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 4.9 | 9.7 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 4.8 | 101.3 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 4.7 | 107.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 4.7 | 4.7 | GO:0032427 | GBD domain binding(GO:0032427) |
| 4.7 | 9.4 | GO:0031403 | lithium ion binding(GO:0031403) |
| 4.7 | 14.0 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
| 4.7 | 102.6 | GO:0070628 | proteasome binding(GO:0070628) |
| 4.6 | 41.1 | GO:0016274 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 4.6 | 45.5 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 4.5 | 40.6 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 4.5 | 17.9 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 4.4 | 35.5 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 4.4 | 8.8 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 4.4 | 17.6 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 4.4 | 17.6 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 4.4 | 13.2 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 4.3 | 13.0 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 4.3 | 13.0 | GO:0046921 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 4.3 | 17.3 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 4.3 | 12.8 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 4.3 | 29.8 | GO:0005497 | androgen binding(GO:0005497) |
| 4.3 | 8.5 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 4.2 | 12.7 | GO:0052839 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 4.2 | 46.5 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 4.2 | 12.6 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 4.2 | 29.3 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 4.2 | 12.5 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 4.2 | 4.2 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 4.2 | 20.8 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 4.1 | 24.9 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 4.1 | 24.8 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 4.1 | 20.6 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 4.1 | 24.6 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 4.1 | 16.3 | GO:0102345 | 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345) |
| 4.0 | 4.0 | GO:0043813 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) |
| 4.0 | 24.0 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 4.0 | 4.0 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 3.9 | 86.4 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 3.9 | 31.4 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 3.9 | 54.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 3.9 | 70.0 | GO:0043495 | protein anchor(GO:0043495) |
| 3.9 | 11.6 | GO:0003860 | 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860) |
| 3.9 | 15.5 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 3.9 | 15.4 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 3.9 | 11.6 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 3.8 | 19.2 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 3.8 | 7.6 | GO:0043398 | HLH domain binding(GO:0043398) |
| 3.8 | 22.7 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 3.8 | 15.1 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 3.8 | 11.3 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 3.8 | 30.0 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 3.7 | 41.2 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 3.7 | 164.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 3.7 | 11.2 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 3.7 | 14.9 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 3.7 | 110.9 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 3.7 | 25.8 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) ornithine decarboxylase regulator activity(GO:0042979) |
| 3.7 | 48.0 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 3.7 | 81.2 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 3.7 | 176.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 3.7 | 102.6 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 3.6 | 3.6 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 3.6 | 21.7 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 3.6 | 93.3 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 3.6 | 67.5 | GO:0048156 | tau protein binding(GO:0048156) |
| 3.5 | 28.4 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 3.5 | 91.8 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 3.5 | 10.5 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) |
| 3.5 | 52.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 3.5 | 28.0 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 3.5 | 20.9 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 3.4 | 3.4 | GO:0038049 | transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) |
| 3.4 | 78.4 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) |
| 3.4 | 10.2 | GO:0070704 | C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704) |
| 3.4 | 10.1 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 3.4 | 13.5 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 3.4 | 33.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 3.4 | 10.1 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
| 3.3 | 13.4 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 3.3 | 6.7 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 3.3 | 23.3 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 3.3 | 30.0 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 3.3 | 73.0 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 3.3 | 13.3 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 3.3 | 29.8 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 3.3 | 26.1 | GO:0052832 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 3.3 | 32.5 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 3.2 | 61.7 | GO:0000339 | RNA cap binding(GO:0000339) |
| 3.2 | 12.9 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 3.2 | 48.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 3.2 | 44.9 | GO:0031489 | myosin V binding(GO:0031489) |
| 3.2 | 19.2 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 3.2 | 31.8 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 3.2 | 133.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 3.1 | 65.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 3.1 | 6.2 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 3.1 | 1411.6 | GO:0045296 | cadherin binding(GO:0045296) |
| 3.1 | 9.3 | GO:0033989 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594) |
| 3.1 | 21.5 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 3.1 | 18.4 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 3.1 | 9.2 | GO:0030957 | Tat protein binding(GO:0030957) |
| 3.1 | 33.6 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 3.0 | 133.0 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 3.0 | 3.0 | GO:0016530 | metallochaperone activity(GO:0016530) |
| 3.0 | 21.1 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 2.9 | 8.8 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
| 2.9 | 8.8 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 2.9 | 11.6 | GO:0036033 | mediator complex binding(GO:0036033) |
| 2.9 | 8.7 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 2.9 | 11.6 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 2.9 | 11.5 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 2.8 | 96.7 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 2.8 | 39.8 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 2.8 | 11.3 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 2.8 | 93.2 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 2.8 | 11.3 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 2.8 | 50.8 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 2.8 | 90.0 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 2.8 | 33.7 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 2.8 | 8.4 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 2.8 | 8.4 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 2.8 | 11.0 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 2.8 | 13.8 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 2.7 | 43.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 2.7 | 8.1 | GO:0050146 | nucleoside phosphotransferase activity(GO:0050146) |
| 2.7 | 43.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 2.7 | 105.2 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 2.7 | 21.5 | GO:0050733 | RS domain binding(GO:0050733) |
| 2.7 | 10.8 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 2.7 | 8.0 | GO:0034416 | bisphosphoglycerate phosphatase activity(GO:0034416) |
| 2.7 | 8.0 | GO:0043035 | chromatin insulator sequence binding(GO:0043035) |
| 2.7 | 74.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 2.6 | 15.9 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 2.6 | 7.9 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 2.6 | 13.2 | GO:0032143 | single thymine insertion binding(GO:0032143) |
| 2.6 | 5.2 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 2.6 | 99.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 2.6 | 83.3 | GO:0003785 | actin monomer binding(GO:0003785) |
| 2.6 | 13.0 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 2.6 | 46.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 2.6 | 10.3 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 2.5 | 10.2 | GO:0070363 | mitochondrial light strand promoter sense binding(GO:0070363) |
| 2.5 | 66.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 2.5 | 40.4 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 2.5 | 45.4 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 2.5 | 32.8 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 2.5 | 7.4 | GO:0034512 | box C/D snoRNA binding(GO:0034512) |
| 2.5 | 34.4 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 2.5 | 2.5 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
| 2.4 | 4.8 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 2.4 | 9.7 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 2.4 | 24.0 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 2.4 | 35.9 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 2.4 | 7.2 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 2.4 | 11.9 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 2.4 | 62.0 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 2.4 | 14.3 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 2.4 | 16.6 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 2.4 | 14.2 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 2.4 | 2.4 | GO:0032810 | sterol response element binding(GO:0032810) |
| 2.3 | 16.4 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 2.3 | 23.2 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 2.3 | 2.3 | GO:0004335 | galactokinase activity(GO:0004335) |
| 2.3 | 30.1 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 2.3 | 34.4 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 2.3 | 6.9 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 2.3 | 6.9 | GO:0098809 | oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
| 2.3 | 9.1 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 2.3 | 11.3 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 2.3 | 18.0 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 2.2 | 4.5 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 2.2 | 51.5 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 2.2 | 4.5 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 2.2 | 26.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 2.2 | 13.3 | GO:0071253 | connexin binding(GO:0071253) |
| 2.2 | 24.3 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 2.2 | 6.6 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 2.2 | 37.2 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 2.2 | 13.0 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
| 2.2 | 34.6 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 2.1 | 19.3 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 2.1 | 4.3 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 2.1 | 6.4 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 2.1 | 29.6 | GO:0044548 | S100 protein binding(GO:0044548) |
| 2.1 | 12.6 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 2.1 | 39.9 | GO:0051400 | BH domain binding(GO:0051400) |
| 2.1 | 43.8 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 2.1 | 10.4 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 2.1 | 27.1 | GO:0001968 | fibronectin binding(GO:0001968) |
| 2.1 | 16.6 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 2.1 | 14.5 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 2.1 | 10.4 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 2.1 | 12.4 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 2.1 | 66.0 | GO:0043236 | laminin binding(GO:0043236) |
| 2.1 | 2.1 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
| 2.0 | 373.9 | GO:0051015 | actin filament binding(GO:0051015) |
| 2.0 | 12.2 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 2.0 | 98.0 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 2.0 | 5.9 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 2.0 | 17.6 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 1.9 | 7.8 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 1.9 | 35.0 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 1.9 | 23.3 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 1.9 | 94.6 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 1.9 | 5.8 | GO:0042947 | glucoside transmembrane transporter activity(GO:0042947) |
| 1.9 | 19.1 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 1.9 | 39.9 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 1.9 | 17.1 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 1.9 | 11.2 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 1.9 | 18.6 | GO:0031014 | troponin T binding(GO:0031014) |
| 1.8 | 14.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 1.8 | 1.8 | GO:0018812 | 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) |
| 1.8 | 7.3 | GO:0019798 | procollagen-proline dioxygenase activity(GO:0019798) |
| 1.8 | 29.1 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 1.8 | 7.3 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 1.8 | 5.4 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 1.8 | 7.2 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 1.8 | 1.8 | GO:0031544 | peptidyl-proline 3-dioxygenase activity(GO:0031544) |
| 1.8 | 7.0 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 1.7 | 5.2 | GO:0034736 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 1.7 | 7.0 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 1.7 | 15.7 | GO:0050692 | DBD domain binding(GO:0050692) |
| 1.7 | 3.5 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
| 1.7 | 6.9 | GO:0030548 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 1.7 | 12.1 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 1.7 | 12.0 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 1.7 | 30.0 | GO:0031491 | nucleosome binding(GO:0031491) |
| 1.6 | 6.5 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 1.6 | 1.6 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
| 1.6 | 30.9 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 1.6 | 24.2 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 1.6 | 17.6 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 1.6 | 17.6 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 1.6 | 6.4 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 1.6 | 17.4 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 1.6 | 18.7 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 1.6 | 9.3 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 1.6 | 45.0 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 1.5 | 10.7 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 1.5 | 4.6 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 1.5 | 37.9 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 1.5 | 4.5 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 1.5 | 4.5 | GO:0004056 | argininosuccinate lyase activity(GO:0004056) |
| 1.5 | 22.7 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
| 1.5 | 34.6 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
| 1.5 | 49.6 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 1.5 | 13.5 | GO:0034452 | dynactin binding(GO:0034452) |
| 1.5 | 6.0 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 1.5 | 11.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 1.5 | 20.8 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 1.5 | 8.9 | GO:0022884 | macromolecule transmembrane transporter activity(GO:0022884) |
| 1.5 | 32.5 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 1.5 | 7.4 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 1.5 | 10.3 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 1.5 | 16.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 1.5 | 347.0 | GO:0003924 | GTPase activity(GO:0003924) |
| 1.5 | 2.9 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 1.5 | 4.4 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 1.4 | 244.9 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.4 | 14.0 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 1.4 | 46.0 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 1.4 | 9.7 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 1.4 | 45.3 | GO:0034062 | RNA polymerase activity(GO:0034062) |
| 1.4 | 6.8 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 1.4 | 10.8 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 1.3 | 2.7 | GO:0055100 | adiponectin binding(GO:0055100) |
| 1.3 | 21.4 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 1.3 | 5.3 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 1.3 | 15.6 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 1.3 | 15.4 | GO:0043295 | glutathione binding(GO:0043295) |
| 1.3 | 41.0 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 1.3 | 50.0 | GO:0005507 | copper ion binding(GO:0005507) |
| 1.3 | 6.4 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 1.3 | 105.0 | GO:0009055 | electron carrier activity(GO:0009055) |
| 1.3 | 5.1 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 1.3 | 8.8 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 1.3 | 3.8 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 1.2 | 5.0 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 1.2 | 6.2 | GO:0097016 | L27 domain binding(GO:0097016) |
| 1.2 | 9.8 | GO:0089720 | caspase binding(GO:0089720) |
| 1.2 | 44.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 1.2 | 26.8 | GO:0019956 | chemokine binding(GO:0019956) |
| 1.2 | 9.7 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 1.2 | 50.9 | GO:0015485 | cholesterol binding(GO:0015485) |
| 1.2 | 3.6 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 1.2 | 9.5 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 1.2 | 24.9 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 1.2 | 7.1 | GO:0050700 | CARD domain binding(GO:0050700) |
| 1.2 | 17.6 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 1.2 | 10.6 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 1.2 | 82.2 | GO:0008565 | protein transporter activity(GO:0008565) |
| 1.2 | 25.7 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 1.2 | 7.0 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 1.2 | 4.7 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 1.1 | 10.3 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 1.1 | 14.8 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 1.1 | 15.9 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 1.1 | 2.3 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 1.1 | 25.6 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 1.1 | 3.3 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 1.1 | 2.2 | GO:0008199 | ferric iron binding(GO:0008199) |
| 1.1 | 4.2 | GO:0097617 | annealing activity(GO:0097617) |
| 1.1 | 3.2 | GO:0080101 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 1.0 | 4.2 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 1.0 | 9.3 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 1.0 | 4.1 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 1.0 | 14.4 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 1.0 | 3.1 | GO:0004958 | prostaglandin F receptor activity(GO:0004958) |
| 1.0 | 9.2 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 1.0 | 5.1 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 1.0 | 2.0 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 1.0 | 3.0 | GO:0052794 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 1.0 | 4.0 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
| 1.0 | 7.8 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 1.0 | 2.0 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 1.0 | 13.6 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
| 1.0 | 4.9 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 1.0 | 8.7 | GO:0005521 | lamin binding(GO:0005521) |
| 1.0 | 5.7 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.9 | 8.5 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.9 | 62.3 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.9 | 144.6 | GO:0008201 | heparin binding(GO:0008201) |
| 0.9 | 10.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.9 | 16.8 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.9 | 42.2 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.9 | 14.6 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.9 | 37.3 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.9 | 2.7 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 0.9 | 2.7 | GO:0070984 | SET domain binding(GO:0070984) |
| 0.9 | 2.7 | GO:0000252 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012) |
| 0.9 | 116.7 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.9 | 77.1 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.9 | 7.0 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.9 | 26.2 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.9 | 12.2 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.9 | 13.8 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.9 | 54.2 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.9 | 0.9 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
| 0.8 | 6.8 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.8 | 2.5 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 0.8 | 48.1 | GO:0005518 | collagen binding(GO:0005518) |
| 0.8 | 0.8 | GO:0015563 | uptake transmembrane transporter activity(GO:0015563) |
| 0.8 | 7.6 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.8 | 1.7 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.8 | 7.4 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.8 | 4.9 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.8 | 188.8 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.8 | 13.7 | GO:0030228 | lipoprotein particle receptor activity(GO:0030228) |
| 0.8 | 4.8 | GO:0070513 | death domain binding(GO:0070513) |
| 0.8 | 12.6 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.8 | 3.1 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.8 | 1.6 | GO:0030619 | U1 snRNA binding(GO:0030619) |
| 0.8 | 6.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.8 | 12.3 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.8 | 1.5 | GO:0004122 | cystathionine beta-synthase activity(GO:0004122) |
| 0.8 | 3.0 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 0.8 | 2.3 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.8 | 16.6 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.8 | 21.1 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.7 | 9.7 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.7 | 2.2 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.7 | 11.0 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.7 | 5.1 | GO:0016679 | oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) |
| 0.7 | 18.8 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.7 | 7.8 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.7 | 33.9 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.7 | 6.3 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.7 | 6.3 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.7 | 2.1 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.7 | 8.3 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.7 | 2.0 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.7 | 4.0 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.7 | 3.3 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.7 | 15.3 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.6 | 5.2 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.6 | 1.3 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
| 0.6 | 3.8 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.6 | 8.2 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 0.6 | 12.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.6 | 3.0 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.6 | 2.4 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.6 | 55.7 | GO:0005178 | integrin binding(GO:0005178) |
| 0.6 | 2.3 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.6 | 2.9 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.6 | 21.7 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.6 | 1.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.6 | 1.7 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.6 | 9.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.5 | 2.2 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.5 | 4.3 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.5 | 0.5 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 0.5 | 17.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.5 | 7.4 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.5 | 2.1 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.5 | 3.1 | GO:0050294 | flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294) |
| 0.5 | 5.6 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.5 | 34.7 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.5 | 3.0 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.5 | 57.9 | GO:0020037 | heme binding(GO:0020037) |
| 0.5 | 2.9 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.5 | 4.2 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.5 | 12.0 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.5 | 1.4 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.4 | 5.3 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.4 | 1.3 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 0.4 | 28.8 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.4 | 10.5 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.4 | 17.4 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.4 | 1.2 | GO:0045569 | TRAIL binding(GO:0045569) |
| 0.4 | 2.8 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.4 | 6.8 | GO:0019239 | deaminase activity(GO:0019239) |
| 0.4 | 2.0 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.4 | 3.9 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.4 | 1.2 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.4 | 5.4 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 0.4 | 2.3 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.4 | 4.6 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.4 | 1.1 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.4 | 4.9 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.4 | 1.1 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 0.4 | 24.2 | GO:0002020 | protease binding(GO:0002020) |
| 0.4 | 20.4 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.4 | 1.5 | GO:0033897 | ribonuclease T2 activity(GO:0033897) |
| 0.4 | 1.4 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.3 | 4.5 | GO:0016289 | CoA hydrolase activity(GO:0016289) acyl-CoA hydrolase activity(GO:0047617) |
| 0.3 | 2.8 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.3 | 1.0 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 0.3 | 3.7 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
| 0.3 | 8.3 | GO:0004438 | phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744) |
| 0.3 | 1.0 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 0.3 | 1.6 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.3 | 3.8 | GO:0016651 | oxidoreductase activity, acting on NAD(P)H(GO:0016651) |
| 0.3 | 0.6 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 0.3 | 2.4 | GO:0050664 | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664) |
| 0.3 | 4.9 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.3 | 1.4 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.3 | 0.6 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 0.3 | 1.7 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.3 | 1.9 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.3 | 260.3 | GO:0003723 | RNA binding(GO:0003723) |
| 0.2 | 5.2 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.2 | 1.7 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) |
| 0.2 | 0.7 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.2 | 1.8 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.2 | 0.7 | GO:1901611 | phosphatidylglycerol binding(GO:1901611) |
| 0.2 | 0.2 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.2 | 0.8 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
| 0.2 | 0.5 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
| 0.2 | 1.1 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.2 | 0.5 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.2 | 0.8 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.1 | 0.9 | GO:0048256 | flap endonuclease activity(GO:0048256) |
| 0.1 | 0.6 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.1 | 0.7 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 0.1 | 1.0 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 0.5 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.1 | 0.3 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.1 | 0.2 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 0.3 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.0 | 0.3 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.0 | 1.8 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.2 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 0.1 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.0 | 0.0 | GO:0016725 | oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) |
| 0.0 | 0.1 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.0 | 0.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.1 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.0 | 0.1 | GO:0050542 | icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
| 0.0 | 0.1 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.2 | 16.5 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 8.2 | 188.7 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 6.4 | 172.4 | PID ARF 3PATHWAY | Arf1 pathway |
| 6.3 | 321.5 | PID BARD1 PATHWAY | BARD1 signaling events |
| 5.9 | 59.3 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 5.7 | 234.1 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 5.7 | 323.2 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 5.6 | 480.8 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 5.3 | 228.8 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 4.7 | 14.1 | PID EPO PATHWAY | EPO signaling pathway |
| 4.5 | 50.0 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 4.1 | 78.6 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 4.1 | 8.2 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 3.8 | 15.4 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 3.7 | 7.4 | PID IFNG PATHWAY | IFN-gamma pathway |
| 3.7 | 59.0 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 3.6 | 170.4 | PID ALK1 PATHWAY | ALK1 signaling events |
| 3.6 | 39.7 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 3.2 | 190.8 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 3.1 | 405.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 3.1 | 6.1 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 2.8 | 87.4 | PID ATM PATHWAY | ATM pathway |
| 2.8 | 157.9 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 2.7 | 78.9 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 2.6 | 5.2 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 2.6 | 12.8 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 2.5 | 15.3 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 2.4 | 45.8 | PID IGF1 PATHWAY | IGF1 pathway |
| 2.4 | 160.0 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 2.3 | 57.1 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 2.1 | 76.9 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 1.9 | 17.0 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 1.8 | 198.9 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 1.8 | 45.2 | PID FOXO PATHWAY | FoxO family signaling |
| 1.8 | 46.9 | PID RHOA PATHWAY | RhoA signaling pathway |
| 1.8 | 78.5 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 1.8 | 14.2 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 1.8 | 92.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 1.8 | 70.8 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 1.8 | 72.2 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 1.8 | 82.6 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 1.8 | 3.5 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 1.7 | 93.0 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 1.7 | 92.7 | PID P53 REGULATION PATHWAY | p53 pathway |
| 1.7 | 77.9 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 1.7 | 20.0 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 1.5 | 17.0 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 1.5 | 48.4 | PID ATR PATHWAY | ATR signaling pathway |
| 1.5 | 50.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 1.4 | 27.1 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 1.4 | 18.4 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 1.4 | 106.3 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 1.3 | 5.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 1.3 | 24.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 1.3 | 53.4 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 1.3 | 76.4 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 1.3 | 8.9 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 1.3 | 12.5 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 1.2 | 68.9 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 1.2 | 93.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 1.1 | 22.6 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 1.1 | 18.9 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 1.1 | 61.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 1.1 | 3.3 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 1.1 | 23.9 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 1.1 | 60.2 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 1.1 | 48.0 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 1.0 | 25.1 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 1.0 | 13.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 1.0 | 5.1 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 1.0 | 56.6 | PID E2F PATHWAY | E2F transcription factor network |
| 0.9 | 45.6 | PID P73PATHWAY | p73 transcription factor network |
| 0.8 | 11.3 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.7 | 10.4 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.7 | 5.9 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.7 | 5.1 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.7 | 8.8 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.7 | 2.7 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.6 | 39.6 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.6 | 22.9 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.6 | 1.9 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.6 | 12.0 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.5 | 12.5 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.5 | 4.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.5 | 11.9 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.5 | 13.4 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.5 | 17.3 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.5 | 8.4 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.4 | 13.6 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.4 | 12.2 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.4 | 4.4 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.4 | 34.8 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.4 | 1.1 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.4 | 91.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.4 | 10.7 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.3 | 12.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.3 | 4.7 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.3 | 6.0 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.3 | 1.2 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.3 | 12.9 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.2 | 6.0 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.2 | 1.9 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.2 | 1.5 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.2 | 4.1 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 3.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.6 | 276.9 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 10.5 | 21.1 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 9.2 | 423.0 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 8.4 | 8.4 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 8.3 | 116.8 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 8.2 | 123.7 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 8.2 | 90.0 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 7.9 | 291.8 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 7.4 | 245.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 7.3 | 175.7 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 7.0 | 202.6 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 6.6 | 483.6 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 6.5 | 13.0 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 6.4 | 96.7 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 6.1 | 318.8 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 6.0 | 125.0 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 5.9 | 235.4 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 5.5 | 77.5 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 5.3 | 121.2 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 5.1 | 56.6 | REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 |
| 5.1 | 30.7 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 5.0 | 105.3 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 4.8 | 53.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 4.8 | 33.8 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 4.7 | 97.8 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 4.6 | 136.7 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 4.5 | 163.3 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 4.5 | 40.6 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 4.4 | 47.9 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 4.3 | 412.9 | REACTOME APOPTOTIC EXECUTION PHASE | Genes involved in Apoptotic execution phase |
| 4.3 | 38.3 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 4.3 | 89.3 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 4.2 | 121.9 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 4.2 | 74.9 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 4.1 | 135.8 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 4.1 | 156.1 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 4.1 | 102.0 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 4.0 | 95.4 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 3.7 | 172.3 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 3.7 | 44.5 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 3.7 | 140.3 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 3.7 | 69.6 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 3.6 | 123.2 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 3.6 | 83.0 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 3.5 | 200.8 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 3.5 | 27.8 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 3.4 | 61.2 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 3.4 | 61.0 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 3.4 | 10.1 | REACTOME TRANSCRIPTION COUPLED NER TC NER | Genes involved in Transcription-coupled NER (TC-NER) |
| 3.3 | 43.4 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 3.3 | 196.6 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 3.3 | 55.3 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 3.2 | 148.0 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 3.2 | 331.4 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 3.1 | 56.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 3.1 | 168.6 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 3.1 | 77.8 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 3.1 | 68.0 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 3.1 | 126.0 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 3.1 | 55.2 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 3.1 | 189.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 3.0 | 146.4 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 3.0 | 74.5 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 3.0 | 198.8 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 2.9 | 46.4 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 2.7 | 191.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 2.7 | 30.0 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 2.7 | 121.4 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 2.7 | 107.3 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 2.6 | 63.0 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 2.6 | 78.4 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 2.6 | 268.6 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 2.5 | 90.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 2.5 | 34.6 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 2.4 | 24.0 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 2.4 | 43.1 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 2.3 | 56.2 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 2.3 | 41.9 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 2.3 | 34.5 | REACTOME DNA STRAND ELONGATION | Genes involved in DNA strand elongation |
| 2.2 | 31.4 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 2.2 | 370.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 2.2 | 8.8 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 2.2 | 28.2 | REACTOME SIGNALING BY NOTCH2 | Genes involved in Signaling by NOTCH2 |
| 2.2 | 58.5 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 2.0 | 142.8 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 1.9 | 45.6 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 1.9 | 3.8 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 1.9 | 49.1 | REACTOME KINESINS | Genes involved in Kinesins |
| 1.9 | 11.3 | REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
| 1.8 | 18.1 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 1.7 | 136.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 1.7 | 20.6 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 1.7 | 22.1 | REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 1.6 | 32.6 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 1.6 | 1.6 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 1.6 | 12.8 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 1.6 | 156.7 | REACTOME INFLUENZA LIFE CYCLE | Genes involved in Influenza Life Cycle |
| 1.6 | 20.3 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 1.5 | 23.2 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 1.5 | 18.4 | REACTOME P75NTR SIGNALS VIA NFKB | Genes involved in p75NTR signals via NF-kB |
| 1.5 | 25.8 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 1.4 | 28.9 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 1.4 | 31.2 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 1.4 | 23.8 | REACTOME M G1 TRANSITION | Genes involved in M/G1 Transition |
| 1.4 | 6.9 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 1.4 | 5.5 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 1.4 | 36.6 | REACTOME TRANSLATION | Genes involved in Translation |
| 1.3 | 6.3 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 1.2 | 8.7 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 1.2 | 66.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 1.2 | 14.2 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 1.1 | 14.9 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 1.0 | 17.7 | REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | Genes involved in Nuclear Events (kinase and transcription factor activation) |
| 1.0 | 24.0 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 1.0 | 20.5 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 1.0 | 13.2 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 1.0 | 16.1 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 1.0 | 8.0 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 1.0 | 16.7 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 1.0 | 33.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 1.0 | 27.6 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.9 | 22.6 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.9 | 12.0 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.9 | 18.3 | REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| 0.9 | 11.5 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.8 | 13.4 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.8 | 15.4 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.8 | 17.8 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.7 | 9.6 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.7 | 55.9 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.7 | 46.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.7 | 5.5 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.7 | 7.5 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.7 | 10.6 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.7 | 7.3 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.7 | 8.5 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.6 | 7.7 | REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | Genes involved in Class I MHC mediated antigen processing & presentation |
| 0.6 | 17.6 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.6 | 57.8 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.6 | 16.0 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.5 | 6.3 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.5 | 9.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.5 | 14.7 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.5 | 11.0 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.5 | 6.5 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.4 | 17.1 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.4 | 31.2 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.4 | 0.8 | REACTOME DEADENYLATION DEPENDENT MRNA DECAY | Genes involved in Deadenylation-dependent mRNA decay |
| 0.4 | 9.1 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.4 | 4.9 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.4 | 11.1 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.4 | 5.4 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.3 | 6.1 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.3 | 2.9 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 0.3 | 9.6 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.3 | 2.7 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.3 | 11.8 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.3 | 12.1 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.3 | 38.3 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |
| 0.3 | 28.1 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.3 | 6.5 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.2 | 0.7 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.2 | 1.8 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.2 | 0.7 | REACTOME G2 M CHECKPOINTS | Genes involved in G2/M Checkpoints |
| 0.2 | 2.1 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.2 | 1.3 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.2 | 7.1 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.2 | 3.5 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.1 | 1.7 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 2.2 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 1.0 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.1 | 2.5 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.1 | 0.6 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 0.2 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 1.1 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 0.5 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 0.2 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 2.6 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.1 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |