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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SP3

Z-value: 12.31

Motif logo

Transcription factors associated with SP3

Gene Symbol Gene ID Gene Info
ENSG00000172845.18 SP3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SP3hg38_v1_chr2_-_173964180_173964240,
hg38_v1_chr2_-_173964069_173964157
0.666.7e-29Click!

Activity profile of SP3 motif

Sorted Z-values of SP3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SP3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_89948697 108.29 ENST00000567999.5
ENST00000610455.4
ENST00000617948.4
ENST00000566079.5
ENST00000566820.5
ENST00000562578.5
ENST00000563594.6
ENST00000561741.5
ENST00000268676.11
ENST00000562986.5
ENST00000569453.5
ENST00000567884.5
ENST00000569061.5
ENST00000418391.6
ENST00000561959.5
ENST00000567874.5
ENST00000570182.5
ENST00000563795.1
differentially expressed in FDCP 8 homolog
chrX_-_153724343 105.76 ENST00000442093.5
ENST00000345046.12
ENST00000645377.1
ENST00000672675.1
ENST00000647529.1
ENST00000429550.5
B cell receptor associated protein 31
chr19_-_55407719 94.06 ENST00000587845.5
ENST00000589978.1
ENST00000264552.14
ubiquitin conjugating enzyme E2 S
chr11_+_65919331 87.74 ENST00000376991.6
DR1 associated protein 1
chr2_-_10448318 86.61 ENST00000234111.9
ornithine decarboxylase 1
chr19_-_291365 86.39 ENST00000591572.2
ENST00000269812.7
ENST00000633125.1
ENST00000434325.7
phospholipid phosphatase 2
chr1_-_8878706 85.85 ENST00000646156.1
enolase 1
chr2_+_234952009 85.76 ENST00000392011.7
SH3 domain binding protein 4
chr8_+_26291758 83.11 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr6_-_158644709 82.94 ENST00000367089.8
dynein light chain Tctex-type 1
chr8_-_140635617 82.08 ENST00000220592.10
argonaute RISC catalytic component 2
chr1_-_8879170 81.69 ENST00000489867.2
enolase 1
chr1_-_8878646 80.73 ENST00000643438.1
enolase 1
chr11_+_1947278 80.05 ENST00000381519.5
ENST00000397298.8
ENST00000397297.7
ENST00000381514.7
ENST00000397294.7
mitochondrial ribosomal protein L23
chr18_+_11981488 80.04 ENST00000269159.8
inositol monophosphatase 2
chr11_+_65919261 79.77 ENST00000525501.5
DR1 associated protein 1
chr1_-_25906457 76.97 ENST00000426559.6
stathmin 1
chr7_+_99374675 76.67 ENST00000645391.1
ENST00000455009.6
actin related protein 2/3 complex subunit 1B
chr1_-_53945661 76.46 ENST00000194214.10
heat shock protein family B (small) member 11
chr6_-_4135459 76.28 ENST00000495548.1
ENST00000380125.6
ENST00000465828.5
ENST00000380118.8
ENST00000361538.6
enoyl-CoA delta isomerase 2
chr1_+_236395394 75.70 ENST00000359362.6
EDAR associated death domain
chr21_-_44818119 75.41 ENST00000411651.6
small ubiquitin like modifier 3
chrX_+_119468436 74.30 ENST00000317881.9
solute carrier family 25 member 5
chr19_-_291132 72.78 ENST00000327790.7
phospholipid phosphatase 2
chr2_+_108534353 71.11 ENST00000544547.5
LIM zinc finger domain containing 1
chr1_+_43358968 70.75 ENST00000310955.11
cell division cycle 20
chr1_-_152036984 70.72 ENST00000271638.3
S100 calcium binding protein A11
chr10_-_133373332 70.17 ENST00000368547.4
enoyl-CoA hydratase, short chain 1
chr11_+_65919480 69.84 ENST00000527119.5
DR1 associated protein 1
chr7_+_26201705 69.61 ENST00000396386.7
ENST00000456948.5
ENST00000409747.5
chromobox 3
chr1_-_8878677 69.01 ENST00000234590.10
ENST00000647408.1
enolase 1
chr11_-_2929412 67.63 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr22_-_19178402 67.38 ENST00000451283.5
solute carrier family 25 member 1
chr19_+_48993864 66.75 ENST00000595090.6
RuvB like AAA ATPase 2
chr21_-_44818043 66.56 ENST00000397898.7
ENST00000332859.11
small ubiquitin like modifier 3
chr15_-_90994494 66.55 ENST00000559811.1
ENST00000442656.6
ENST00000557905.5
ENST00000394249.8
protein regulator of cytokinesis 1
chr17_-_4949037 65.92 ENST00000572383.1
profilin 1
chr2_-_214809650 65.57 ENST00000260947.9
ENST00000613706.5
BRCA1 associated RING domain 1
chr12_-_108731505 65.44 ENST00000261401.8
ENST00000552871.5
coronin 1C
chr8_+_144354640 64.24 ENST00000532815.2
solute carrier family 52 member 2
chr1_+_10399054 64.12 ENST00000270776.13
ENST00000483936.5
phosphogluconate dehydrogenase
chr20_+_33993646 64.06 ENST00000375114.7
ENST00000448364.5
RALY heterogeneous nuclear ribonucleoprotein
chr19_+_16076485 63.92 ENST00000643579.2
ENST00000646575.1
tropomyosin 4
chr2_-_178451094 63.47 ENST00000677981.1
ENST00000678845.1
ENST00000677689.1
ENST00000325748.9
ENST00000678775.1
protein activator of interferon induced protein kinase EIF2AK2
chr2_-_214809597 63.44 ENST00000619009.5
ENST00000421162.2
ENST00000617164.5
ENST00000613374.5
ENST00000620057.4
BRCA1 associated RING domain 1
chr20_+_63739751 63.26 ENST00000266077.5
SLC2A4 regulator
chr19_+_48321454 62.90 ENST00000599704.5
epithelial membrane protein 3
chr11_+_65919383 62.89 ENST00000312515.7
DR1 associated protein 1
chr9_-_110256466 61.71 ENST00000374515.9
ENST00000374517.6
thioredoxin
chr18_+_12947982 61.67 ENST00000262124.15
SEH1 like nucleoporin
chr15_-_90233902 61.56 ENST00000328649.11
ENST00000650306.1
calcium and integrin binding 1
chrX_-_153724044 61.11 ENST00000423827.5
ENST00000458587.8
B cell receptor associated protein 31
chr11_+_65919687 61.04 ENST00000532933.1
DR1 associated protein 1
chr16_-_87869497 61.04 ENST00000261622.5
solute carrier family 7 member 5
chr19_+_6361743 60.86 ENST00000597326.6
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr9_+_89311187 60.56 ENST00000314355.7
CDC28 protein kinase regulatory subunit 2
chr13_+_30422487 60.52 ENST00000638137.1
ENST00000635918.2
ubiquitin conjugating enzyme E2 L5
chr21_-_44817968 60.50 ENST00000397893.3
small ubiquitin like modifier 3
chr7_-_105522204 60.35 ENST00000356362.6
pseudouridine synthase 7
chr1_-_225653045 60.03 ENST00000366843.6
ENST00000366844.7
ENAH actin regulator
chr18_+_12948001 59.94 ENST00000399892.7
ENST00000585730.5
ENST00000589446.5
ENST00000587761.1
SEH1 like nucleoporin
chr17_-_21042901 59.42 ENST00000261497.9
ubiquitin specific peptidase 22
chr20_-_5126534 59.27 ENST00000379160.3
proliferating cell nuclear antigen
chr19_-_32675139 59.08 ENST00000586693.7
ENST00000587352.5
ENST00000306065.9
ENST00000586463.5
ankyrin repeat domain 27
chr20_-_62143374 58.99 ENST00000370873.9
ENST00000370858.3
proteasome 20S subunit alpha 7
chr12_-_118061153 58.37 ENST00000315436.8
ENST00000544233.5
WD repeat and SOCS box containing 2
chr8_-_101205455 58.34 ENST00000520984.5
zinc finger protein 706
chr3_-_53255990 58.29 ENST00000423525.6
transketolase
chr15_+_65869974 58.18 ENST00000567671.1
RAB11A, member RAS oncogene family
chr2_+_121737100 58.13 ENST00000455432.5
translin
chr17_+_1829981 58.10 ENST00000254719.10
replication protein A1
chr1_-_1891056 56.72 ENST00000378609.9
ENST00000610897.4
ENST00000615252.4
G protein subunit beta 1
chr22_+_43151527 56.35 ENST00000583777.5
ENST00000337554.8
translocator protein
chr8_-_54022441 56.32 ENST00000396401.7
ENST00000521604.7
ENST00000640382.1
ENST00000640041.1
transcription elongation factor A1
chr10_-_17617235 56.24 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr22_-_19178719 56.06 ENST00000215882.10
solute carrier family 25 member 1
chr1_-_225427897 55.94 ENST00000421383.1
ENST00000272163.9
lamin B receptor
chr18_+_11981548 55.75 ENST00000588927.5
inositol monophosphatase 2
chr9_-_136866265 55.73 ENST00000371648.4
ENST00000371649.5
endothelial differentiation related factor 1
chr20_+_58981208 55.71 ENST00000602795.6
ENST00000652272.2
negative elongation factor complex member C/D
chr2_-_178450764 55.69 ENST00000487082.5
protein activator of interferon induced protein kinase EIF2AK2
chr7_+_816609 55.50 ENST00000457378.6
ENST00000389574.7
ENST00000452783.6
ENST00000435699.5
ENST00000440380.5
ENST00000439679.5
ENST00000424128.5
Sad1 and UNC84 domain containing 1
chr1_+_53946323 55.47 ENST00000371370.8
ENST00000319223.8
ENST00000444987.1
leucine rich repeat containing 42
chr1_+_43358998 55.16 ENST00000372462.1
cell division cycle 20
chr21_-_39183398 54.83 ENST00000331573.8
proteasome assembly chaperone 1
chr18_+_657637 54.79 ENST00000323274.15
thymidylate synthetase
chr3_-_53256009 54.77 ENST00000296289.10
ENST00000462138.6
ENST00000423516.5
transketolase
chr1_+_166839425 54.69 ENST00000449930.5
ENST00000367876.9
pogo transposable element derived with KRAB domain
chr20_+_62302896 54.15 ENST00000620230.4
ENST00000253003.7
adhesion regulating molecule 1
chr7_+_99374722 54.05 ENST00000418347.6
ENST00000429246.6
ENST00000417330.6
ENST00000431816.6
ENST00000458033.6
ENST00000451682.5
ENST00000427217.6
ENST00000646101.2
actin related protein 2/3 complex subunit 1B
chr2_-_10812706 53.99 ENST00000272227.8
protein disulfide isomerase family A member 6
chr21_+_41167774 53.91 ENST00000328735.10
ENST00000347667.5
beta-secretase 2
chr20_+_408030 53.80 ENST00000640614.1
ENST00000475269.5
RANBP2-type and C3HC4-type zinc finger containing 1
chr18_+_12308232 53.69 ENST00000590103.5
ENST00000591909.5
ENST00000586653.5
ENST00000317702.10
ENST00000592683.5
ENST00000590967.5
ENST00000591208.1
ENST00000591463.1
tubulin beta 6 class V
chr2_-_10812794 53.61 ENST00000540494.5
protein disulfide isomerase family A member 6
chrX_+_149540593 53.53 ENST00000450602.6
ENST00000441248.5
endothelium and lymphocyte associated ASCH domain 1
chr22_+_43151931 53.48 ENST00000329563.8
ENST00000396265.4
translocator protein
chr3_-_177197429 53.39 ENST00000457928.7
TBL1X receptor 1
chr15_-_90234046 53.24 ENST00000612800.1
calcium and integrin binding 1
chr18_+_158513 53.24 ENST00000400266.7
ENST00000580410.5
ENST00000261601.8
ENST00000383589.6
ubiquitin specific peptidase 14
chr2_+_237692144 53.01 ENST00000289175.10
ENST00000244815.9
LRR binding FLII interacting protein 1
chr4_-_156971769 52.71 ENST00000502773.6
platelet derived growth factor C
chr5_-_134004921 52.67 ENST00000265333.8
voltage dependent anion channel 1
chr11_-_535514 52.60 ENST00000451590.5
ENST00000311189.8
ENST00000417302.6
HRas proto-oncogene, GTPase
chr8_+_38996899 52.59 ENST00000677582.1
ENST00000676643.1
ENST00000676936.1
ENST00000677004.1
ENST00000487273.7
ENST00000481513.5
ADAM metallopeptidase domain 9
chr10_+_119104075 52.35 ENST00000472379.2
ENST00000361432.3
ENST00000648560.1
DENN domain containing 10
chr16_+_1309714 52.07 ENST00000566587.5
ubiquitin conjugating enzyme E2 I
chr1_+_228082660 51.57 ENST00000540651.5
ENST00000272102.10
ADP ribosylation factor 1
chr17_-_82648428 51.52 ENST00000392325.9
WD repeat domain 45B
chr8_+_60517169 51.36 ENST00000529579.5
RAB2A, member RAS oncogene family
chr19_-_1568301 51.30 ENST00000402693.5
mex-3 RNA binding family member D
chr19_-_42302576 51.25 ENST00000262890.8
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr2_+_237692290 51.23 ENST00000420665.5
ENST00000392000.4
LRR binding FLII interacting protein 1
chr17_-_4948519 51.16 ENST00000225655.6
profilin 1
chr7_+_55887277 51.13 ENST00000426595.1
novel zinc finger protein 713 (ZNF713) and mitochondrial ribosomal protein S17 (MRPS17) protein
chr12_+_52948840 50.98 ENST00000388837.6
ENST00000550600.5
keratin 18
chr20_-_35284745 50.90 ENST00000374443.7
ENST00000374450.8
eukaryotic translation initiation factor 6
chr14_-_68979436 50.86 ENST00000193403.10
actinin alpha 1
chr6_+_24774925 50.65 ENST00000356509.7
ENST00000230056.8
geminin DNA replication inhibitor
chr16_+_88857086 50.58 ENST00000567895.5
ENST00000301021.7
ENST00000625770.2
ENST00000565504.5
ENST00000567312.5
ENST00000568583.5
ENST00000561840.1
trafficking protein particle complex 2 like
chr1_-_112707314 50.41 ENST00000369642.7
ras homolog family member C
chr18_+_11981015 50.27 ENST00000589238.5
inositol monophosphatase 2
chrX_+_119574748 50.16 ENST00000628549.1
ubiquitin conjugating enzyme E2 A
chrX_+_65667645 50.15 ENST00000360270.7
moesin
chr13_-_30465224 50.13 ENST00000399494.5
high mobility group box 1
chr3_+_23805941 50.08 ENST00000306627.8
ENST00000346855.7
ubiquitin conjugating enzyme E2 E1
chr16_-_81096336 49.96 ENST00000639169.1
ENST00000315467.9
glycine cleavage system protein H
chr20_-_35284715 49.66 ENST00000374436.7
ENST00000675032.1
eukaryotic translation initiation factor 6
chr1_+_40979659 49.63 ENST00000650070.2
ENST00000649864.1
ENST00000649124.1
CTP synthase 1
chr6_-_18264475 49.61 ENST00000515742.2
ENST00000651624.1
ENST00000507591.2
ENST00000652689.1
ENST00000244776.11
ENST00000503715.5
DEK proto-oncogene
chr5_-_10761156 49.37 ENST00000432074.2
ENST00000230895.11
death associated protein
chr7_-_106284971 49.34 ENST00000681878.1
ENST00000679951.1
ENST00000680823.1
ENST00000222553.8
ENST00000679643.1
nicotinamide phosphoribosyltransferase
chr6_+_138404206 49.30 ENST00000607197.6
ENST00000367697.7
heme binding protein 2
chr4_-_173334249 49.19 ENST00000506267.1
ENST00000296503.10
high mobility group box 2
chr7_+_56051685 49.18 ENST00000335503.3
chaperonin containing TCP1 subunit 6A
chr1_-_11060000 49.14 ENST00000376957.7
spermidine synthase
chr11_+_832887 48.92 ENST00000524748.6
ENST00000397420.9
ENST00000397421.5
ENST00000322008.9
ENST00000525718.6
ENST00000529810.5
ENST00000526693.5
ENST00000525333.5
ENST00000527341.5
CD151 molecule (Raph blood group)
chr4_+_56435730 48.81 ENST00000514888.5
ENST00000264221.6
ENST00000505164.5
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr20_+_33993904 48.73 ENST00000246194.8
RALY heterogeneous nuclear ribonucleoprotein
chr4_-_10116724 48.58 ENST00000502702.5
WD repeat domain 1
chr2_-_9630946 48.55 ENST00000446619.1
ENST00000238081.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr2_+_10122730 48.49 ENST00000304567.10
ribonucleotide reductase regulatory subunit M2
chr19_+_54190268 48.46 ENST00000429671.7
ENST00000302937.8
ENST00000667261.1
tRNA splicing endonuclease subunit 34
chr1_+_26280117 48.34 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr21_-_39349048 48.33 ENST00000380748.5
ENST00000380749.10
high mobility group nucleosome binding domain 1
chr7_+_32957385 48.27 ENST00000538336.5
ENST00000242209.9
FKBP prolyl isomerase 9
chr16_-_81096163 48.06 ENST00000566566.2
ENST00000569885.6
ENST00000561801.2
ENST00000639689.1
ENST00000638948.1
ENST00000564536.2
ENST00000638192.1
ENST00000640345.1
glycine cleavage system protein H
novel protein
novel protein
chr3_+_100334780 48.02 ENST00000497785.1
nitrilase family member 2
chr1_-_112707056 48.00 ENST00000369633.6
ENST00000425265.6
ENST00000369632.6
ENST00000436685.6
ENST00000484054.3
ENST00000369636.6
ENST00000369637.5
ENST00000339083.12
ENST00000285735.6
ENST00000369638.6
ras homolog family member C
chr2_-_105398978 47.98 ENST00000408995.5
ENST00000530340.6
ENST00000393353.7
ENST00000322142.13
ENST00000344213.9
ENST00000358129.8
four and a half LIM domains 2
chr3_+_49674344 47.81 ENST00000296456.10
ENST00000442186.5
ENST00000438011.5
ENST00000457042.1
acylaminoacyl-peptide hydrolase
chr1_-_150974823 47.72 ENST00000361419.9
ENST00000368954.10
ceramide synthase 2
chr18_+_31498168 47.52 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr15_+_56918763 47.37 ENST00000557843.5
transcription factor 12
chr7_+_116525524 47.36 ENST00000405348.6
caveolin 1
chr7_+_116499687 47.31 ENST00000222693.5
ENST00000343213.2
caveolin 2
chr4_+_173168800 47.24 ENST00000512285.5
ENST00000265000.9
polypeptide N-acetylgalactosaminyltransferase 7
chr19_-_42302292 47.21 ENST00000594989.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr17_+_37489882 47.15 ENST00000617516.5
dual specificity phosphatase 14
chr7_-_106284934 47.12 ENST00000680468.1
ENST00000489358.5
ENST00000491027.6
ENST00000441045.6
ENST00000417537.2
nicotinamide phosphoribosyltransferase
chr8_+_26291494 47.11 ENST00000380737.8
ENST00000524169.5
protein phosphatase 2 regulatory subunit Balpha
chr22_-_43187078 46.91 ENST00000216129.7
tubulin tyrosine ligase like 12
chr7_+_56051756 46.86 ENST00000275603.9
chaperonin containing TCP1 subunit 6A
chr6_+_57172290 46.74 ENST00000370693.5
BAG cochaperone 2
chr5_+_138753412 46.72 ENST00000520339.5
ENST00000627109.2
ENST00000302763.12
ENST00000518910.5
catenin alpha 1
chr10_+_3067496 46.70 ENST00000381125.9
phosphofructokinase, platelet
chr7_-_97872099 46.69 ENST00000437628.5
asparagine synthetase (glutamine-hydrolyzing)
chr10_-_5889832 46.61 ENST00000380092.8
ENST00000380094.10
ENST00000191063.8
ankyrin repeat domain 16
chr22_-_36387949 46.59 ENST00000216181.11
myosin heavy chain 9
chr5_-_134004635 46.51 ENST00000425992.2
ENST00000395044.7
ENST00000395047.6
voltage dependent anion channel 1
chr19_+_48993525 46.47 ENST00000601968.5
ENST00000596837.5
RuvB like AAA ATPase 2
chr11_-_14643617 46.45 ENST00000418988.2
proteasome 20S subunit alpha 1
chr7_-_97872120 46.41 ENST00000394309.7
ENST00000414884.1
ENST00000442734.5
asparagine synthetase (glutamine-hydrolyzing)
chr4_+_56436131 46.38 ENST00000399688.7
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr1_+_26280059 46.36 ENST00000270792.10
SH3 domain binding glutamate rich protein like 3
chr3_+_172040554 46.35 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr14_-_68979314 46.22 ENST00000684713.1
ENST00000683198.1
ENST00000684598.1
ENST00000682331.1
ENST00000682291.1
ENST00000683342.1
actinin alpha 1
chr19_-_48391505 46.06 ENST00000600980.1
ENST00000330720.7
KDEL endoplasmic reticulum protein retention receptor 1
chr15_-_72231113 45.88 ENST00000565154.6
ENST00000565184.6
ENST00000335181.10
pyruvate kinase M1/2
chr17_-_82273424 45.71 ENST00000398519.9
ENST00000580446.1
casein kinase 1 delta
chr3_-_182980531 45.41 ENST00000292782.9
ENST00000632685.1
defective in cullin neddylation 1 domain containing 1
chr1_-_150974867 45.39 ENST00000271688.10
ceramide synthase 2
chr11_+_65181920 45.36 ENST00000279247.11
ENST00000532285.1
ENST00000534373.5
calpain 1
chrX_+_134460138 45.29 ENST00000298556.8
hypoxanthine phosphoribosyltransferase 1
chr19_-_1095261 45.27 ENST00000585838.2
ENST00000586746.5
ENST00000619917.4
ENST00000615234.5
ENST00000612655.4
RNA polymerase II, I and III subunit E
chr2_+_264913 45.16 ENST00000439645.6
ENST00000405233.5
ENST00000272065.10
acid phosphatase 1
chr12_-_6753134 45.11 ENST00000203630.10
myeloid leukemia factor 2
chr14_-_105021043 45.09 ENST00000392590.3
ENST00000336219.4
cell division cycle associated 4
chr17_-_75154503 45.06 ENST00000409753.8
ENST00000581874.1
Jupiter microtubule associated homolog 1
chr17_-_979726 44.98 ENST00000336868.8
nucleoredoxin
chr7_+_16646131 44.82 ENST00000415365.5
ENST00000433922.6
ENST00000630952.2
ENST00000258761.8
ENST00000405202.5
basic leucine zipper and W2 domains 2
chr12_-_76084612 44.52 ENST00000535020.6
ENST00000552342.5
nucleosome assembly protein 1 like 1
chr1_+_220094086 44.37 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chrX_+_2691270 44.24 ENST00000381187.8
ENST00000381184.6
CD99 molecule (Xg blood group)
chr7_+_116526277 44.06 ENST00000393468.1
ENST00000393467.1
caveolin 1
chr8_-_63038788 43.91 ENST00000518113.2
ENST00000260118.7
ENST00000677482.1
gamma-glutamyl hydrolase
chr19_+_34365173 43.87 ENST00000589640.5
ENST00000591204.5
ENST00000589399.6
ENST00000356487.11
glucose-6-phosphate isomerase
chr9_+_33265013 43.87 ENST00000223500.9
charged multivesicular body protein 5
chr2_+_200811882 43.74 ENST00000409600.6
basic leucine zipper and W2 domains 1
chr7_+_74453790 43.56 ENST00000265755.7
ENST00000424337.7
ENST00000455841.6
GTF2I repeat domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
48.0 239.8 GO:0019322 pentose biosynthetic process(GO:0019322)
42.8 171.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
40.4 161.6 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
39.9 119.7 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
39.0 39.0 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
37.3 186.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
35.9 143.5 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
35.6 142.3 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
34.2 136.9 GO:0007113 endomitotic cell cycle(GO:0007113)
32.5 65.1 GO:0006097 glyoxylate cycle(GO:0006097)
31.7 348.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
31.1 93.3 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
30.2 30.2 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
30.1 90.2 GO:1902822 regulation of late endosome to lysosome transport(GO:1902822)
29.9 179.5 GO:0006021 inositol biosynthetic process(GO:0006021)
29.9 119.4 GO:0010796 regulation of multivesicular body size(GO:0010796)
29.2 87.7 GO:0046452 dihydrofolate metabolic process(GO:0046452)
29.2 116.7 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
28.7 28.7 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
28.4 85.3 GO:0090669 telomerase RNA stabilization(GO:0090669)
27.5 137.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
27.2 81.7 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
27.1 27.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
26.3 52.6 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
26.0 182.3 GO:0006231 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
25.9 77.6 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
25.8 77.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
25.1 100.3 GO:1903976 negative regulation of glial cell migration(GO:1903976)
24.9 249.4 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
24.9 124.4 GO:0015862 uridine transport(GO:0015862)
24.7 49.4 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
24.7 98.7 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
24.2 72.7 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
23.7 118.3 GO:0035900 response to isolation stress(GO:0035900)
23.3 116.6 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
23.3 116.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
23.3 116.4 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
22.8 318.5 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
22.5 90.2 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
22.3 156.1 GO:0032218 riboflavin transport(GO:0032218)
22.2 88.8 GO:2000653 regulation of genetic imprinting(GO:2000653)
22.1 88.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
22.0 88.1 GO:0007144 female meiosis I(GO:0007144)
22.0 131.7 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
21.8 87.3 GO:0006167 AMP biosynthetic process(GO:0006167)
21.5 322.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
21.5 64.5 GO:0006059 hexitol metabolic process(GO:0006059)
21.4 150.1 GO:0030421 defecation(GO:0030421)
21.3 63.9 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
21.2 42.3 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
20.9 83.5 GO:0090095 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
20.9 62.6 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
20.7 62.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
20.5 81.8 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
20.3 142.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
20.1 60.4 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
20.1 100.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
20.1 80.4 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
20.0 100.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
20.0 59.9 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
19.6 58.7 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
19.5 312.5 GO:0043248 proteasome assembly(GO:0043248)
19.3 425.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
19.2 249.5 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
19.0 57.0 GO:0006226 dUMP biosynthetic process(GO:0006226)
18.9 94.5 GO:0006177 GMP biosynthetic process(GO:0006177)
18.6 93.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
18.5 74.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
18.4 202.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
18.4 146.8 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
18.3 54.9 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
18.2 36.4 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
18.1 108.9 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
18.1 36.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
18.1 162.8 GO:0006265 DNA topological change(GO:0006265)
18.0 90.0 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
17.9 53.6 GO:0090149 mitochondrial membrane fission(GO:0090149)
17.6 35.2 GO:0070476 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
17.6 211.1 GO:0015939 pantothenate metabolic process(GO:0015939)
17.5 70.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
17.4 52.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
17.3 121.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
17.3 69.3 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
17.2 172.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
17.2 86.0 GO:0060613 fat pad development(GO:0060613)
17.1 68.4 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
17.1 51.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
17.0 51.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
17.0 17.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
16.8 101.0 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
16.8 67.2 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
16.6 49.9 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
16.3 98.0 GO:0097052 L-kynurenine metabolic process(GO:0097052)
16.1 96.8 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
16.1 273.8 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
16.0 64.0 GO:0043335 protein unfolding(GO:0043335)
15.8 63.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
15.8 63.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
15.8 63.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
15.8 94.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
15.8 47.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
15.7 62.7 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
15.6 46.9 GO:1902905 positive regulation of fibril organization(GO:1902905)
15.5 46.6 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
15.5 185.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
15.5 108.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
15.4 123.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
15.4 15.4 GO:1904814 regulation of protein localization to chromosome, telomeric region(GO:1904814)
15.4 15.4 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
15.4 15.4 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
15.2 45.7 GO:1901389 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
15.2 380.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
15.2 90.9 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
15.0 105.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
14.9 119.5 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
14.9 89.5 GO:0022614 membrane to membrane docking(GO:0022614)
14.8 44.3 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
14.7 44.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
14.7 323.2 GO:0051639 actin filament network formation(GO:0051639)
14.6 58.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
14.6 43.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
14.5 43.6 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
14.5 116.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
14.5 43.5 GO:1903381 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
14.4 14.4 GO:0015809 arginine transport(GO:0015809)
14.4 43.2 GO:1902594 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
14.4 57.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
14.3 200.8 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
14.2 14.2 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
14.2 42.5 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
14.1 42.4 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
14.1 197.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
14.0 196.6 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
13.9 41.8 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
13.9 41.6 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
13.8 41.4 GO:1904387 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
13.8 27.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
13.7 109.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
13.7 68.7 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
13.7 95.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
13.6 218.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
13.5 108.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
13.5 13.5 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
13.4 120.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
13.4 13.4 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
13.3 40.0 GO:0061163 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
13.3 40.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
13.3 159.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
13.3 145.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
13.2 52.7 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
13.0 181.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
13.0 51.8 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
13.0 51.8 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
12.9 51.8 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
12.9 51.7 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
12.9 51.6 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
12.7 51.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
12.7 38.2 GO:1904874 positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
12.7 12.7 GO:0048254 snoRNA localization(GO:0048254)
12.7 50.9 GO:0030047 actin modification(GO:0030047)
12.7 63.4 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
12.7 12.7 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
12.7 38.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
12.7 50.6 GO:0044206 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
12.6 50.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
12.6 63.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
12.6 37.7 GO:0090402 oncogene-induced cell senescence(GO:0090402)
12.6 75.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
12.6 50.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
12.5 25.0 GO:0005997 xylulose metabolic process(GO:0005997)
12.5 62.3 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
12.4 87.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
12.4 384.7 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
12.4 74.4 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
12.3 12.3 GO:0010225 response to UV-C(GO:0010225)
12.3 49.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
12.2 36.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
12.1 48.6 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
12.0 84.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
12.0 108.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
12.0 48.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
12.0 48.0 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
12.0 71.8 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
11.9 47.7 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
11.8 58.9 GO:1904753 negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
11.8 11.8 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
11.7 46.7 GO:0032600 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
11.6 46.5 GO:1903332 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) regulation of protein folding(GO:1903332) negative regulation of protein folding(GO:1903333)
11.6 23.2 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
11.6 23.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
11.6 115.9 GO:0009414 response to water deprivation(GO:0009414)
11.5 46.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
11.5 45.9 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
11.4 68.5 GO:0015853 adenine transport(GO:0015853)
11.4 867.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
11.3 45.3 GO:0043555 regulation of translation in response to stress(GO:0043555)
11.2 56.1 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
11.1 78.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
11.1 178.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
11.1 111.1 GO:0006621 protein retention in ER lumen(GO:0006621)
11.0 220.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
11.0 44.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
11.0 110.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
11.0 22.0 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
10.9 21.9 GO:0046086 adenosine biosynthetic process(GO:0046086)
10.9 130.5 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
10.9 10.9 GO:1901355 response to rapamycin(GO:1901355)
10.8 32.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
10.8 54.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
10.8 54.0 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
10.8 10.8 GO:0003415 chondrocyte hypertrophy(GO:0003415)
10.7 42.8 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
10.7 42.7 GO:0006404 RNA import into nucleus(GO:0006404)
10.7 117.2 GO:0042262 DNA protection(GO:0042262)
10.6 10.6 GO:0009838 abscission(GO:0009838)
10.6 31.8 GO:0001923 B-1 B cell differentiation(GO:0001923)
10.6 137.5 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
10.5 52.5 GO:0061441 renal artery morphogenesis(GO:0061441)
10.5 62.9 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
10.4 20.9 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
10.4 31.2 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
10.4 41.5 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
10.3 20.7 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
10.3 10.3 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
10.3 10.3 GO:0048378 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
10.3 41.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
10.3 41.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
10.2 20.4 GO:0072019 proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
10.2 20.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
10.2 30.6 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
10.2 10.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
10.2 91.8 GO:0000710 meiotic mismatch repair(GO:0000710)
10.2 162.6 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
10.2 60.9 GO:0007296 vitellogenesis(GO:0007296)
10.1 1002.6 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
10.1 20.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
10.1 120.9 GO:0019388 galactose catabolic process(GO:0019388)
10.0 59.8 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
10.0 10.0 GO:0006106 fumarate metabolic process(GO:0006106)
9.9 89.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
9.9 9.9 GO:1905146 lysosomal protein catabolic process(GO:1905146)
9.8 19.7 GO:0031291 Ran protein signal transduction(GO:0031291)
9.8 19.5 GO:0015866 ADP transport(GO:0015866)
9.8 117.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
9.8 87.9 GO:1902661 positive regulation of glucose mediated signaling pathway(GO:1902661)
9.7 58.5 GO:0030043 actin filament fragmentation(GO:0030043)
9.7 48.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
9.7 19.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
9.6 28.9 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
9.6 28.7 GO:1903288 positive regulation of potassium ion import(GO:1903288)
9.5 38.0 GO:0033484 nitric oxide homeostasis(GO:0033484)
9.5 75.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
9.5 66.3 GO:0061198 fungiform papilla formation(GO:0061198)
9.5 28.4 GO:0006781 succinyl-CoA pathway(GO:0006781)
9.5 18.9 GO:0043418 homocysteine catabolic process(GO:0043418)
9.4 18.9 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
9.4 56.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
9.4 18.9 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
9.4 141.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
9.4 18.8 GO:1904872 regulation of telomerase RNA localization to Cajal body(GO:1904872)
9.4 28.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
9.3 46.7 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
9.3 65.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
9.3 9.3 GO:1903911 positive regulation of receptor clustering(GO:1903911)
9.3 55.9 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
9.2 652.4 GO:0045454 cell redox homeostasis(GO:0045454)
9.2 45.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
9.2 404.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
9.2 27.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
9.1 9.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
9.1 72.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
9.1 45.3 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
9.0 54.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
9.0 54.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
9.0 53.9 GO:0015680 intracellular copper ion transport(GO:0015680)
9.0 62.7 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
8.9 26.6 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
8.9 44.4 GO:0003164 His-Purkinje system development(GO:0003164)
8.9 106.4 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
8.8 159.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
8.8 26.4 GO:0002188 translation reinitiation(GO:0002188)
8.8 246.3 GO:0031581 hemidesmosome assembly(GO:0031581)
8.8 8.8 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
8.8 149.1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
8.7 34.9 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
8.7 26.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
8.7 8.7 GO:0009209 pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209)
8.7 26.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
8.7 121.3 GO:0006527 arginine catabolic process(GO:0006527)
8.6 77.5 GO:0001522 pseudouridine synthesis(GO:0001522)
8.6 17.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
8.5 25.6 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
8.5 25.6 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
8.5 127.7 GO:0070986 left/right axis specification(GO:0070986)
8.5 25.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
8.5 17.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
8.4 33.8 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
8.4 67.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
8.4 142.8 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
8.4 67.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
8.3 75.1 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
8.3 75.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
8.3 8.3 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
8.3 190.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
8.3 90.9 GO:0006089 lactate metabolic process(GO:0006089)
8.2 32.8 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
8.2 8.2 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
8.2 24.6 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
8.2 40.9 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
8.2 57.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
8.2 73.5 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
8.2 16.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
8.1 8.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
8.1 32.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
8.1 113.6 GO:0045116 protein neddylation(GO:0045116)
8.1 24.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
8.1 40.3 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
8.1 48.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
8.0 64.3 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
8.0 32.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
8.0 55.9 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
8.0 55.9 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
8.0 31.9 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
7.9 39.4 GO:0040016 embryonic cleavage(GO:0040016)
7.9 47.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
7.8 15.5 GO:0098904 regulation of AV node cell action potential(GO:0098904)
7.8 7.8 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
7.8 54.3 GO:0015846 polyamine transport(GO:0015846)
7.7 23.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
7.7 177.8 GO:0043968 histone H2A acetylation(GO:0043968)
7.7 84.7 GO:0060056 mammary gland involution(GO:0060056)
7.7 30.7 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
7.7 30.7 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
7.7 91.9 GO:0034349 glial cell apoptotic process(GO:0034349)
7.6 99.3 GO:0090168 Golgi reassembly(GO:0090168)
7.6 22.8 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
7.6 7.6 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
7.6 30.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
7.6 37.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
7.6 22.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
7.5 22.6 GO:0051182 coenzyme transport(GO:0051182)
7.5 90.6 GO:0090344 negative regulation of cell aging(GO:0090344)
7.5 15.1 GO:0046543 development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543)
7.5 30.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
7.5 15.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
7.5 22.6 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
7.5 37.4 GO:0070269 pyroptosis(GO:0070269)
7.4 37.1 GO:0061738 late endosomal microautophagy(GO:0061738)
7.4 29.5 GO:1990928 response to amino acid starvation(GO:1990928)
7.4 7.4 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
7.4 22.1 GO:0036363 transforming growth factor beta activation(GO:0036363)
7.3 7.3 GO:0003162 atrioventricular node development(GO:0003162)
7.3 21.9 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
7.2 21.7 GO:1902570 protein localization to nucleolus(GO:1902570)
7.2 86.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
7.2 21.6 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
7.2 143.7 GO:0006337 nucleosome disassembly(GO:0006337)
7.2 71.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
7.2 50.1 GO:2000230 response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
7.1 21.4 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
7.1 21.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
7.1 64.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
7.1 35.5 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
7.1 71.0 GO:0046689 response to mercury ion(GO:0046689)
7.1 21.2 GO:0042946 glucoside transport(GO:0042946)
7.1 14.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
7.1 14.1 GO:1902415 regulation of mRNA binding(GO:1902415)
7.0 84.6 GO:0060546 negative regulation of necroptotic process(GO:0060546)
7.0 42.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
7.0 28.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
6.9 6.9 GO:0006529 asparagine biosynthetic process(GO:0006529)
6.9 20.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
6.9 20.7 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
6.9 75.9 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
6.9 89.4 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
6.9 48.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
6.9 185.5 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
6.9 20.6 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
6.9 27.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
6.8 6.8 GO:0060066 oviduct development(GO:0060066)
6.8 68.3 GO:0060717 chorion development(GO:0060717)
6.8 109.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
6.8 34.1 GO:0061635 regulation of protein complex stability(GO:0061635)
6.8 6.8 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
6.8 6.8 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
6.8 20.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
6.7 53.9 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
6.7 20.2 GO:0002084 protein depalmitoylation(GO:0002084)
6.7 33.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
6.7 33.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
6.7 26.9 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
6.6 19.9 GO:2000619 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619)
6.6 13.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
6.6 33.1 GO:0007341 penetration of zona pellucida(GO:0007341)
6.6 19.8 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
6.6 33.0 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
6.6 39.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
6.6 13.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
6.5 19.6 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
6.5 124.1 GO:0006101 citrate metabolic process(GO:0006101)
6.5 97.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
6.5 84.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
6.5 25.8 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
6.5 25.8 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
6.4 6.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
6.4 38.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
6.4 473.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
6.4 38.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
6.4 19.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
6.4 19.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
6.3 63.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
6.3 12.7 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
6.3 19.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
6.3 25.3 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
6.3 25.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
6.3 12.5 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
6.3 43.8 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
6.3 81.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
6.2 55.9 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
6.2 24.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
6.2 12.4 GO:0033182 regulation of histone ubiquitination(GO:0033182)
6.2 12.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
6.2 18.5 GO:0045047 protein targeting to ER(GO:0045047)
6.1 110.6 GO:1900027 regulation of ruffle assembly(GO:1900027)
6.1 159.4 GO:0016578 histone deubiquitination(GO:0016578)
6.1 134.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
6.1 42.8 GO:0030091 protein repair(GO:0030091)
6.1 55.0 GO:2000774 positive regulation of cellular senescence(GO:2000774)
6.1 30.5 GO:0000733 DNA strand renaturation(GO:0000733)
6.1 48.8 GO:0035865 cellular response to potassium ion(GO:0035865)
6.1 12.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
6.1 231.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
6.1 97.3 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
6.1 48.5 GO:0044854 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
6.1 12.1 GO:0046031 ADP metabolic process(GO:0046031)
6.1 12.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
6.1 54.5 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
6.1 30.3 GO:0006574 valine catabolic process(GO:0006574)
6.0 42.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
6.0 24.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
6.0 54.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
6.0 215.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
6.0 23.9 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
6.0 17.9 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
6.0 6.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
6.0 59.6 GO:0000212 meiotic spindle organization(GO:0000212)
6.0 23.8 GO:0000012 single strand break repair(GO:0000012)
5.9 23.7 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
5.9 29.6 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
5.9 17.7 GO:0097384 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
5.9 41.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
5.9 5.9 GO:0051660 establishment of centrosome localization(GO:0051660)
5.9 29.4 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
5.9 11.7 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
5.8 163.5 GO:0006465 signal peptide processing(GO:0006465)
5.8 17.5 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
5.8 40.8 GO:0035879 plasma membrane lactate transport(GO:0035879)
5.8 58.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
5.8 5.8 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
5.8 75.4 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
5.8 11.5 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
5.7 51.7 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
5.7 5.7 GO:0021539 subthalamus development(GO:0021539)
5.7 102.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
5.7 17.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
5.7 34.2 GO:0001765 membrane raft assembly(GO:0001765)
5.7 170.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
5.6 62.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
5.6 5.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
5.6 11.2 GO:0016584 nucleosome positioning(GO:0016584)
5.6 78.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
5.6 11.2 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
5.6 61.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
5.6 50.1 GO:0001866 NK T cell proliferation(GO:0001866)
5.5 11.1 GO:0048102 autophagic cell death(GO:0048102)
5.5 16.5 GO:1901421 positive regulation of response to alcohol(GO:1901421)
5.5 5.5 GO:0072289 metanephric nephron tubule formation(GO:0072289)
5.5 44.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
5.5 22.0 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
5.5 11.0 GO:0009180 ADP biosynthetic process(GO:0006172) nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
5.5 5.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
5.5 365.8 GO:0090114 COPII-coated vesicle budding(GO:0090114)
5.4 21.8 GO:1904045 cellular response to aldosterone(GO:1904045)
5.4 10.8 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
5.4 16.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
5.4 16.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
5.4 160.5 GO:0006270 DNA replication initiation(GO:0006270)
5.3 32.1 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
5.3 37.4 GO:0070294 renal sodium ion absorption(GO:0070294)
5.3 32.0 GO:0006415 translational termination(GO:0006415)
5.3 79.9 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
5.3 5.3 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
5.3 89.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
5.3 15.8 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
5.2 41.9 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
5.2 36.6 GO:0033327 Leydig cell differentiation(GO:0033327)
5.2 10.4 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
5.2 31.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
5.2 10.3 GO:1901419 regulation of response to alcohol(GO:1901419)
5.2 118.5 GO:0007035 vacuolar acidification(GO:0007035)
5.1 313.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
5.1 10.2 GO:0019087 transformation of host cell by virus(GO:0019087)
5.1 45.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
5.1 30.5 GO:0031337 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
5.1 60.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
5.1 15.2 GO:0070203 regulation of establishment of protein localization to telomere(GO:0070203)
5.1 50.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
5.0 15.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
5.0 50.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
5.0 5.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
4.9 49.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
4.9 14.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
4.9 14.6 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
4.9 87.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
4.9 14.6 GO:0010768 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
4.8 43.3 GO:0075713 establishment of integrated proviral latency(GO:0075713)
4.8 14.4 GO:0000103 sulfate assimilation(GO:0000103)
4.8 19.2 GO:0008215 spermine metabolic process(GO:0008215)
4.8 33.5 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
4.7 33.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
4.7 14.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
4.7 9.5 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
4.7 18.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
4.7 14.1 GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity(GO:0090176)
4.7 9.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
4.7 18.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
4.6 18.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
4.6 18.5 GO:0010643 cell communication by chemical coupling(GO:0010643)
4.6 23.1 GO:0044375 regulation of peroxisome size(GO:0044375)
4.6 18.5 GO:0089700 protein kinase D signaling(GO:0089700)
4.6 60.0 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
4.6 9.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
4.6 9.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
4.6 4.6 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
4.6 4.6 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
4.6 36.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
4.5 40.9 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
4.5 72.4 GO:0032486 Rap protein signal transduction(GO:0032486)
4.5 45.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
4.5 22.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
4.5 8.9 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
4.4 26.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
4.4 17.7 GO:0003409 optic cup structural organization(GO:0003409)
4.4 22.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
4.4 4.4 GO:0043144 snoRNA processing(GO:0043144)
4.4 439.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
4.4 17.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
4.4 140.3 GO:0000281 mitotic cytokinesis(GO:0000281)
4.4 17.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
4.4 21.8 GO:0051451 myoblast migration(GO:0051451)
4.3 8.7 GO:0048539 bone marrow development(GO:0048539)
4.3 125.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
4.3 47.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
4.3 8.6 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
4.3 55.8 GO:0060712 spongiotrophoblast layer development(GO:0060712)
4.3 8.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
4.3 17.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
4.3 42.8 GO:0045793 positive regulation of cell size(GO:0045793)
4.3 68.5 GO:0033260 nuclear DNA replication(GO:0033260)
4.3 8.5 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
4.3 89.5 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
4.3 76.7 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
4.2 25.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
4.2 8.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
4.2 25.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
4.2 50.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
4.2 4.2 GO:0072174 metanephric tubule formation(GO:0072174)
4.2 37.7 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
4.2 29.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
4.2 33.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
4.1 116.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
4.1 8.3 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
4.1 37.1 GO:0007379 segment specification(GO:0007379)
4.1 8.2 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
4.1 65.7 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
4.1 12.3 GO:0042369 vitamin D catabolic process(GO:0042369)
4.1 57.3 GO:0032392 DNA geometric change(GO:0032392)
4.1 73.5 GO:0071294 cellular response to zinc ion(GO:0071294)
4.1 8.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
4.1 12.2 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
4.1 125.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
4.1 16.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
4.0 24.1 GO:0060356 leucine import(GO:0060356)
4.0 24.1 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
4.0 20.1 GO:0015677 copper ion import(GO:0015677)
4.0 24.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
4.0 4.0 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
4.0 15.9 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
4.0 11.9 GO:2000706 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
3.9 3.9 GO:0035026 leading edge cell differentiation(GO:0035026)
3.9 63.1 GO:0061157 mRNA destabilization(GO:0061157)
3.9 11.8 GO:0001832 blastocyst growth(GO:0001832)
3.9 15.7 GO:0045218 zonula adherens maintenance(GO:0045218)
3.9 23.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
3.9 7.8 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
3.9 62.4 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
3.8 23.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
3.8 3.8 GO:0071336 submandibular salivary gland formation(GO:0060661) white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
3.8 19.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
3.8 11.4 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
3.8 7.6 GO:0040031 snRNA modification(GO:0040031)
3.8 151.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
3.8 138.9 GO:0007031 peroxisome organization(GO:0007031)
3.7 37.5 GO:0006907 pinocytosis(GO:0006907)
3.7 11.2 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
3.7 14.9 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
3.7 29.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
3.7 11.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
3.7 11.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
3.7 11.1 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
3.7 7.3 GO:0060434 bronchus morphogenesis(GO:0060434)
3.7 22.0 GO:0070200 establishment of protein localization to telomere(GO:0070200)
3.7 58.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
3.7 84.0 GO:0035329 hippo signaling(GO:0035329)
3.7 11.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
3.7 11.0 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
3.6 36.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
3.6 105.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
3.6 36.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
3.6 28.8 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316)
3.6 7.2 GO:0010044 response to aluminum ion(GO:0010044)
3.6 3.6 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
3.6 32.2 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
3.6 35.6 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
3.6 53.3 GO:0090383 phagosome acidification(GO:0090383)
3.5 10.6 GO:0051683 establishment of Golgi localization(GO:0051683)
3.5 7.1 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
3.5 161.4 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
3.5 10.5 GO:0003064 regulation of heart rate by hormone(GO:0003064)
3.5 34.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
3.5 10.4 GO:2000489 hepatic stellate cell activation(GO:0035733) regulation of hepatic stellate cell activation(GO:2000489) positive regulation of hepatic stellate cell activation(GO:2000491)
3.5 10.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
3.5 7.0 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
3.5 146.1 GO:0018208 peptidyl-proline modification(GO:0018208)
3.5 48.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
3.5 10.4 GO:0006642 triglyceride mobilization(GO:0006642)
3.5 13.8 GO:0050917 sensory perception of umami taste(GO:0050917)
3.5 13.8 GO:0042659 regulation of cell fate specification(GO:0042659)
3.4 3.4 GO:2000576 positive regulation of microtubule motor activity(GO:2000576)
3.4 13.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
3.4 20.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
3.4 3.4 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
3.4 44.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
3.4 20.3 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
3.4 33.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
3.4 23.7 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
3.4 16.9 GO:0002934 desmosome organization(GO:0002934)
3.4 16.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
3.4 16.8 GO:0080009 mRNA methylation(GO:0080009)
3.4 13.5 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
3.4 16.8 GO:0019348 dolichol metabolic process(GO:0019348)
3.4 37.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
3.4 6.7 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
3.4 10.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
3.3 73.6 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
3.3 63.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
3.3 6.7 GO:0071314 cellular response to cocaine(GO:0071314)
3.3 53.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
3.3 59.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
3.3 13.2 GO:2000035 regulation of stem cell division(GO:2000035)
3.3 13.1 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
3.3 26.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
3.3 58.8 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
3.3 9.8 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
3.3 19.6 GO:0042182 ketone catabolic process(GO:0042182)
3.3 3.3 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
3.3 9.8 GO:0010455 positive regulation of cell fate commitment(GO:0010455)
3.3 22.8 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
3.2 3.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
3.2 29.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
3.2 6.4 GO:0007518 myoblast fate determination(GO:0007518)
3.2 9.6 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
3.2 22.5 GO:0042407 cristae formation(GO:0042407)
3.2 25.6 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
3.2 12.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
3.2 3.2 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
3.2 38.0 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
3.2 9.5 GO:0090188 signal transduction by trans-phosphorylation(GO:0023016) negative regulation of pancreatic juice secretion(GO:0090188)
3.1 9.4 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
3.1 12.5 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
3.1 34.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
3.1 6.2 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
3.1 34.1 GO:0017121 phospholipid scrambling(GO:0017121)
3.1 3.1 GO:0007506 gonadal mesoderm development(GO:0007506)
3.1 12.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
3.1 24.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
3.1 30.8 GO:0000022 mitotic spindle elongation(GO:0000022)
3.1 36.9 GO:0046040 IMP metabolic process(GO:0046040)
3.1 18.4 GO:0031017 exocrine pancreas development(GO:0031017)
3.1 15.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
3.1 12.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
3.0 12.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
3.0 182.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
3.0 9.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
3.0 12.1 GO:0071763 nuclear membrane organization(GO:0071763)
3.0 21.2 GO:0042255 ribosome assembly(GO:0042255)
3.0 63.3 GO:0009649 entrainment of circadian clock(GO:0009649)
3.0 12.1 GO:0002265 astrocyte activation involved in immune response(GO:0002265) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
3.0 9.0 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
3.0 30.1 GO:0033622 integrin activation(GO:0033622)
3.0 24.0 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
3.0 11.9 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
3.0 14.9 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
3.0 26.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
2.9 90.0 GO:0034629 cellular protein complex localization(GO:0034629)
2.9 5.8 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
2.9 2.9 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
2.9 157.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
2.9 34.3 GO:0070327 thyroid hormone transport(GO:0070327)
2.8 51.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
2.8 11.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
2.8 11.4 GO:1901143 insulin catabolic process(GO:1901143)
2.8 8.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
2.8 2.8 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
2.8 16.8 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
2.8 61.6 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
2.8 14.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
2.8 8.3 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
2.8 22.0 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
2.7 118.1 GO:0043488 regulation of mRNA stability(GO:0043488)
2.7 13.6 GO:0034508 centromere complex assembly(GO:0034508)
2.7 16.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
2.7 27.1 GO:0090382 phagosome maturation(GO:0090382)
2.7 51.6 GO:0045830 positive regulation of isotype switching(GO:0045830)
2.7 51.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
2.7 29.8 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286) positive regulation of caveolin-mediated endocytosis(GO:2001288)
2.7 19.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
2.7 8.1 GO:0051795 positive regulation of catagen(GO:0051795)
2.7 51.0 GO:0009145 purine nucleoside triphosphate biosynthetic process(GO:0009145)
2.7 2.7 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
2.7 21.4 GO:0090161 Golgi ribbon formation(GO:0090161)
2.7 5.3 GO:0007028 cytoplasm organization(GO:0007028)
2.7 26.6 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
2.7 13.3 GO:0043457 regulation of cellular respiration(GO:0043457)
2.6 5.3 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
2.6 21.1 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
2.6 18.4 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
2.6 7.9 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
2.6 5.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
2.6 13.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
2.6 15.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
2.6 5.2 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
2.6 7.8 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
2.6 18.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
2.6 7.8 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
2.6 10.3 GO:1903337 positive regulation of vacuolar transport(GO:1903337)
2.6 36.1 GO:0032060 bleb assembly(GO:0032060)
2.6 2.6 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
2.6 33.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.6 10.3 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
2.5 53.5 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
2.5 15.2 GO:0051014 actin filament severing(GO:0051014)
2.5 5.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
2.5 10.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
2.5 12.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
2.5 117.4 GO:0007569 cell aging(GO:0007569)
2.5 7.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.5 9.9 GO:0045112 integrin biosynthetic process(GO:0045112) regulation of endodermal cell differentiation(GO:1903224)
2.5 29.5 GO:0006903 vesicle targeting(GO:0006903)
2.4 7.3 GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
2.4 14.7 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
2.4 19.4 GO:0031053 primary miRNA processing(GO:0031053)
2.4 122.9 GO:0006334 nucleosome assembly(GO:0006334)
2.4 4.7 GO:0072141 renal interstitial fibroblast development(GO:0072141)
2.4 92.3 GO:0006414 translational elongation(GO:0006414)
2.4 4.7 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
2.3 2.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
2.3 2.3 GO:2000644 regulation of receptor catabolic process(GO:2000644)
2.3 4.7 GO:0033197 response to vitamin E(GO:0033197)
2.3 11.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
2.3 16.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
2.3 13.9 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
2.3 4.6 GO:2000520 positive regulation of mononuclear cell migration(GO:0071677) regulation of immunological synapse formation(GO:2000520) negative regulation of immunological synapse formation(GO:2000521)
2.3 2.3 GO:1990791 dorsal root ganglion development(GO:1990791)
2.3 32.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
2.3 41.3 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
2.3 25.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
2.3 70.7 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
2.3 9.1 GO:2000210 positive regulation of anoikis(GO:2000210)
2.3 38.6 GO:0050873 brown fat cell differentiation(GO:0050873)
2.3 81.4 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
2.3 11.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
2.3 9.0 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
2.2 6.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
2.2 4.5 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
2.2 24.5 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
2.2 6.6 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
2.2 41.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
2.2 28.5 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
2.2 4.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
2.2 2.2 GO:0071306 cellular response to vitamin E(GO:0071306)
2.2 2.2 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
2.2 8.7 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
2.2 8.6 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
2.2 2.2 GO:0060437 lung growth(GO:0060437)
2.2 2.2 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
2.2 45.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
2.2 17.2 GO:0044743 intracellular protein transmembrane import(GO:0044743) establishment of protein localization to mitochondrial membrane(GO:0090151)
2.1 23.4 GO:0038203 TORC2 signaling(GO:0038203)
2.1 23.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
2.1 4.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
2.1 21.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
2.1 75.6 GO:0071470 cellular response to osmotic stress(GO:0071470)
2.1 35.7 GO:0006353 DNA-templated transcription, termination(GO:0006353)
2.1 22.9 GO:0051290 protein heterotetramerization(GO:0051290)
2.1 10.4 GO:0051389 inactivation of MAPKK activity(GO:0051389)
2.1 6.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
2.1 4.1 GO:1903233 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
2.0 36.9 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
2.0 4.1 GO:0051775 response to redox state(GO:0051775)
2.0 6.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
2.0 4.1 GO:1904732 regulation of electron carrier activity(GO:1904732)
2.0 4.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
2.0 11.9 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
2.0 4.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
2.0 23.6 GO:0016540 protein autoprocessing(GO:0016540)
2.0 2.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
2.0 2.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.9 56.3 GO:0045214 sarcomere organization(GO:0045214)
1.9 89.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
1.9 17.4 GO:0044786 cell cycle DNA replication(GO:0044786)
1.9 5.8 GO:0061724 lipophagy(GO:0061724)
1.9 5.8 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
1.9 1.9 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
1.9 66.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
1.9 35.8 GO:0043388 positive regulation of DNA binding(GO:0043388)
1.9 17.0 GO:0042775 ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
1.9 18.8 GO:0021670 lateral ventricle development(GO:0021670)
1.9 7.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
1.9 5.6 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.9 3.7 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
1.9 1.9 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
1.8 24.0 GO:0031639 plasminogen activation(GO:0031639)
1.8 11.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
1.8 1.8 GO:0006623 protein targeting to vacuole(GO:0006623)
1.8 25.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
1.8 1.8 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152)
1.8 20.2 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.8 49.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
1.8 5.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
1.8 5.5 GO:0035425 autocrine signaling(GO:0035425)
1.8 41.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.8 14.4 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
1.8 14.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.8 33.8 GO:0051923 sulfation(GO:0051923)
1.8 3.5 GO:0033591 response to L-ascorbic acid(GO:0033591)
1.8 5.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
1.7 38.3 GO:0035456 response to interferon-beta(GO:0035456)
1.7 15.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
1.7 13.9 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
1.7 3.5 GO:0098502 DNA dephosphorylation(GO:0098502)
1.7 6.9 GO:0043921 modulation by host of viral transcription(GO:0043921) modulation by host of symbiont transcription(GO:0052472)
1.7 130.0 GO:0006364 rRNA processing(GO:0006364)
1.7 3.4 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.7 5.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
1.7 6.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
1.7 64.4 GO:0015893 drug transport(GO:0015893)
1.7 10.1 GO:0032532 regulation of microvillus length(GO:0032532)
1.7 3.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.7 3.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.7 71.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
1.7 8.3 GO:0006573 valine metabolic process(GO:0006573)
1.7 18.2 GO:0008156 negative regulation of DNA replication(GO:0008156)
1.7 6.6 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
1.6 8.2 GO:0014870 response to muscle inactivity(GO:0014870)
1.6 27.9 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
1.6 3.3 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
1.6 8.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.6 14.7 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
1.6 1.6 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.6 66.5 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
1.6 100.0 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
1.6 19.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
1.6 19.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
1.6 31.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.6 4.7 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.6 6.3 GO:0009648 photoperiodism(GO:0009648)
1.6 11.0 GO:0051661 maintenance of centrosome location(GO:0051661)
1.6 9.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.5 7.7 GO:0050915 sensory perception of sour taste(GO:0050915)
1.5 4.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.5 7.6 GO:0072553 terminal button organization(GO:0072553)
1.5 13.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.5 21.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
1.5 13.7 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
1.5 7.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.5 9.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
1.5 21.1 GO:0048745 smooth muscle tissue development(GO:0048745)
1.5 4.5 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
1.5 22.4 GO:0031648 protein destabilization(GO:0031648)
1.5 16.2 GO:0006551 leucine metabolic process(GO:0006551)
1.5 2.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.5 42.1 GO:0061462 protein localization to lysosome(GO:0061462)
1.4 1.4 GO:0032472 Golgi calcium ion transport(GO:0032472)
1.4 8.5 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
1.4 203.1 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
1.4 11.2 GO:0001778 plasma membrane repair(GO:0001778)
1.4 44.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
1.4 4.2 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
1.4 4.2 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
1.4 5.5 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
1.4 9.6 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
1.4 2.7 GO:0002036 regulation of L-glutamate transport(GO:0002036)
1.4 5.4 GO:0019532 oxalate transport(GO:0019532)
1.3 8.1 GO:0008090 retrograde axonal transport(GO:0008090)
1.3 4.0 GO:0097264 self proteolysis(GO:0097264)
1.3 14.7 GO:0016180 snRNA processing(GO:0016180)
1.3 6.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
1.3 6.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
1.3 4.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
1.3 4.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
1.3 1.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
1.3 1.3 GO:0061009 common bile duct development(GO:0061009)
1.3 1.3 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
1.3 16.8 GO:0001909 leukocyte mediated cytotoxicity(GO:0001909)
1.3 24.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
1.3 2.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
1.3 39.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
1.3 2.5 GO:0048840 otolith development(GO:0048840)
1.3 5.1 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
1.3 2.5 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
1.2 3.7 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
1.2 11.0 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
1.2 6.1 GO:0016554 cytidine to uridine editing(GO:0016554)
1.2 1.2 GO:0045091 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
1.2 6.0 GO:0044531 modulation of programmed cell death in other organism(GO:0044531) modulation of apoptotic process in other organism(GO:0044532) modulation by symbiont of host programmed cell death(GO:0052040) modulation of programmed cell death in other organism involved in symbiotic interaction(GO:0052248) modulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052433)
1.2 1.2 GO:0048569 post-embryonic organ development(GO:0048569)
1.2 1.2 GO:0060166 olfactory pit development(GO:0060166)
1.2 5.8 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
1.1 31.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
1.1 16.0 GO:0090224 regulation of spindle organization(GO:0090224)
1.1 1.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
1.1 3.4 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
1.1 7.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.1 6.7 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
1.1 3.2 GO:0072350 tricarboxylic acid metabolic process(GO:0072350)
1.1 4.3 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
1.1 61.9 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
1.1 2.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
1.0 1.0 GO:0007343 egg activation(GO:0007343)
1.0 5.2 GO:0045006 DNA deamination(GO:0045006)
1.0 6.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
1.0 3.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
1.0 2.0 GO:0042414 epinephrine metabolic process(GO:0042414)
1.0 28.9 GO:0017144 drug metabolic process(GO:0017144)
1.0 5.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
1.0 1.0 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
1.0 3.8 GO:0071888 macrophage apoptotic process(GO:0071888)
0.9 2.8 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.9 2.8 GO:0002572 pro-T cell differentiation(GO:0002572)
0.9 10.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.9 0.9 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.9 2.8 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.9 4.6 GO:1903027 regulation of opsonization(GO:1903027)
0.9 12.0 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.9 5.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.9 2.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.9 5.4 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.9 4.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.9 9.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.9 3.4 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.9 0.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.8 7.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.8 2.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.8 3.3 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.8 31.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.8 29.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.8 14.6 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.8 8.1 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.8 15.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.8 13.4 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.8 42.7 GO:0006413 translational initiation(GO:0006413)
0.8 2.3 GO:0036233 glycine import(GO:0036233)
0.8 4.5 GO:0006020 inositol metabolic process(GO:0006020)
0.8 0.8 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.8 14.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.7 5.2 GO:0051642 centrosome localization(GO:0051642)
0.7 6.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.7 3.7 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.7 12.3 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.7 1.4 GO:0006595 polyamine metabolic process(GO:0006595)
0.7 1.4 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.7 2.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.7 4.1 GO:0071569 protein ufmylation(GO:0071569)
0.6 3.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.6 7.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.6 1.9 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.6 1.3 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.6 7.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.6 4.3 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.6 0.6 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.6 1.2 GO:0021764 amygdala development(GO:0021764)
0.6 4.2 GO:0051764 actin crosslink formation(GO:0051764)
0.6 5.4 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.6 5.4 GO:0009309 amine biosynthetic process(GO:0009309)
0.6 1.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.6 2.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.6 3.5 GO:0015838 amino-acid betaine transport(GO:0015838)
0.6 4.7 GO:0006458 'de novo' protein folding(GO:0006458)
0.6 4.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.6 5.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.6 11.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.6 7.9 GO:0003334 keratinocyte development(GO:0003334)
0.6 2.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.5 1.1 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.5 2.2 GO:0009249 protein lipoylation(GO:0009249)
0.5 13.7 GO:0042438 melanin biosynthetic process(GO:0042438)
0.5 41.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.5 1.5 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.5 1.4 GO:0035803 egg coat formation(GO:0035803)
0.5 12.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.5 1.9 GO:0015811 L-cystine transport(GO:0015811)
0.5 9.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.5 2.3 GO:0007619 courtship behavior(GO:0007619)
0.5 0.9 GO:0002638 negative regulation of immunoglobulin production(GO:0002638)
0.5 1.8 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.4 1.8 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.4 3.5 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.4 2.6 GO:0002353 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.4 0.4 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.4 0.8 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.4 5.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.4 1.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 1.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 1.6 GO:2000739 regulation of mesenchymal stem cell differentiation(GO:2000739)
0.4 5.3 GO:0006739 NADP metabolic process(GO:0006739)
0.4 1.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 3.1 GO:1902033 regulation of hematopoietic stem cell proliferation(GO:1902033)
0.3 1.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 1.0 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.3 0.6 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.3 0.3 GO:0032364 oxygen homeostasis(GO:0032364)
0.3 2.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.3 9.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.3 1.1 GO:0001878 response to yeast(GO:0001878)
0.3 0.8 GO:0048664 neuron fate determination(GO:0048664)
0.3 0.3 GO:0006113 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.3 1.5 GO:0033028 myeloid cell apoptotic process(GO:0033028)
0.2 1.2 GO:0002208 somatic recombination of immunoglobulin genes involved in immune response(GO:0002204) somatic diversification of immunoglobulins involved in immune response(GO:0002208) isotype switching(GO:0045190)
0.2 1.0 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.2 0.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 0.4 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 1.0 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.2 2.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 0.2 GO:0003180 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.2 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.2 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.2 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 0.5 GO:0021569 rhombomere 3 development(GO:0021569)
0.2 0.5 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 0.3 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.2 0.2 GO:0060157 urinary bladder development(GO:0060157)
0.2 1.9 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.2 0.8 GO:0046688 response to copper ion(GO:0046688)
0.2 1.4 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.2 2.3 GO:0030811 regulation of nucleotide catabolic process(GO:0030811)
0.1 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 0.4 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 0.4 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 2.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 4.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.5 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.4 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 1.1 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 2.0 GO:0046034 ATP metabolic process(GO:0046034)
0.1 1.1 GO:0006301 postreplication repair(GO:0006301)
0.1 4.9 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 0.3 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.1 GO:0035973 aggrephagy(GO:0035973)
0.1 0.6 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 0.5 GO:1990776 response to angiotensin(GO:1990776)
0.1 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.0 GO:0051006 positive regulation of lipoprotein lipase activity(GO:0051006)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
54.9 164.6 GO:0036284 tubulobulbar complex(GO:0036284)
43.2 345.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
34.7 207.9 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
28.3 113.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
28.1 168.5 GO:0009368 endopeptidase Clp complex(GO:0009368)
28.0 139.9 GO:0042643 actomyosin, actin portion(GO:0042643)
27.5 109.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
27.3 136.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
25.6 128.1 GO:0033503 HULC complex(GO:0033503)
25.0 150.3 GO:0097422 tubular endosome(GO:0097422)
24.0 96.0 GO:0005960 glycine cleavage complex(GO:0005960)
22.8 91.2 GO:0008537 proteasome activator complex(GO:0008537)
22.5 90.1 GO:0071817 MMXD complex(GO:0071817)
22.2 222.0 GO:0097255 R2TP complex(GO:0097255)
21.4 257.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
21.3 106.7 GO:0098837 postsynaptic recycling endosome(GO:0098837)
21.0 147.1 GO:0005663 DNA replication factor C complex(GO:0005663)
20.7 186.3 GO:0005787 signal peptidase complex(GO:0005787)
19.8 218.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
19.2 57.6 GO:0043259 laminin-10 complex(GO:0043259)
18.8 93.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
18.2 109.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
17.8 106.9 GO:0070761 pre-snoRNP complex(GO:0070761)
17.7 17.7 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
17.6 87.9 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
17.6 123.0 GO:0090661 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
17.6 175.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
17.5 192.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
17.3 52.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
17.3 69.3 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
17.3 138.2 GO:0000796 condensin complex(GO:0000796)
17.1 136.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
16.9 135.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
16.8 67.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
16.8 251.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
16.7 317.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
16.7 83.5 GO:0031523 Myb complex(GO:0031523)
16.4 16.4 GO:0097454 Schwann cell microvillus(GO:0097454)
16.2 48.6 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
15.7 63.0 GO:0071942 XPC complex(GO:0071942)
15.7 440.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
15.7 219.2 GO:0090543 Flemming body(GO:0090543)
15.2 45.7 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
14.8 14.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
14.6 58.4 GO:0000811 GINS complex(GO:0000811)
14.6 131.3 GO:0042382 paraspeckles(GO:0042382)
14.6 174.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
14.4 43.2 GO:0044393 microspike(GO:0044393)
14.3 85.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
14.2 57.0 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
14.2 70.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
13.9 237.1 GO:0031080 nuclear pore outer ring(GO:0031080)
13.9 13.9 GO:0031088 platelet dense granule membrane(GO:0031088)
13.9 139.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
13.9 83.5 GO:0031298 replication fork protection complex(GO:0031298)
13.9 97.3 GO:0032021 NELF complex(GO:0032021)
13.8 41.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
13.8 69.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
13.6 95.4 GO:0016589 NURF complex(GO:0016589)
13.6 149.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
13.5 188.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
13.4 120.7 GO:0031595 nuclear proteasome complex(GO:0031595)
13.4 214.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
13.3 13.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
12.9 206.3 GO:0070578 RISC-loading complex(GO:0070578)
12.9 218.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
12.7 63.7 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
12.7 89.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
12.6 377.4 GO:0031143 pseudopodium(GO:0031143)
12.5 50.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
12.5 175.6 GO:0070938 contractile ring(GO:0070938)
12.5 50.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
12.5 87.6 GO:0016272 prefoldin complex(GO:0016272)
12.3 37.0 GO:0030677 ribonuclease P complex(GO:0030677)
12.3 12.3 GO:0089701 U2AF(GO:0089701)
12.3 12.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
12.1 182.0 GO:0034709 methylosome(GO:0034709)
12.1 60.4 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
12.0 168.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
12.0 203.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
11.8 11.8 GO:0044308 axonal spine(GO:0044308)
11.6 57.9 GO:0097149 centralspindlin complex(GO:0097149)
11.4 34.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
11.3 56.6 GO:0001651 dense fibrillar component(GO:0001651)
11.3 236.9 GO:0032433 filopodium tip(GO:0032433)
10.7 42.8 GO:0071986 Ragulator complex(GO:0071986)
10.7 21.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
10.7 309.9 GO:0005680 anaphase-promoting complex(GO:0005680)
10.7 106.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
10.6 84.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
10.6 169.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
10.5 21.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
10.4 135.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
10.2 10.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
10.1 71.0 GO:0005956 protein kinase CK2 complex(GO:0005956)
10.1 30.2 GO:0034515 proteasome storage granule(GO:0034515)
10.0 50.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
9.9 278.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
9.8 68.7 GO:0008290 F-actin capping protein complex(GO:0008290)
9.8 19.6 GO:0031262 Ndc80 complex(GO:0031262)
9.7 58.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
9.7 67.6 GO:0031415 NatA complex(GO:0031415)
9.7 77.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
9.6 47.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
9.6 105.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
9.4 103.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
9.4 74.8 GO:0005688 U6 snRNP(GO:0005688)
9.3 28.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
9.3 55.5 GO:0071797 LUBAC complex(GO:0071797)
9.2 55.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
9.2 359.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
9.2 36.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
9.1 27.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
9.1 45.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
8.9 53.4 GO:0042824 MHC class I peptide loading complex(GO:0042824)
8.8 8.8 GO:1990246 uniplex complex(GO:1990246)
8.7 95.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
8.6 25.9 GO:0045323 interleukin-1 receptor complex(GO:0045323)
8.5 8.5 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
8.4 75.5 GO:0032133 chromosome passenger complex(GO:0032133)
8.4 242.5 GO:0000502 proteasome complex(GO:0000502)
8.3 8.3 GO:0035061 interchromatin granule(GO:0035061)
8.3 24.9 GO:0097409 glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038)
8.2 24.7 GO:0072563 endothelial microparticle(GO:0072563)
8.2 16.3 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
8.1 48.6 GO:0000125 PCAF complex(GO:0000125)
8.1 97.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
8.1 56.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
8.0 232.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
8.0 24.0 GO:0097441 basilar dendrite(GO:0097441)
8.0 71.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
8.0 15.9 GO:1990730 VCP-NSFL1C complex(GO:1990730)
7.9 23.7 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
7.8 258.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
7.8 31.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
7.8 38.9 GO:0032301 MutSalpha complex(GO:0032301)
7.7 68.9 GO:0044754 autolysosome(GO:0044754)
7.6 160.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
7.6 53.3 GO:0044530 supraspliceosomal complex(GO:0044530)
7.6 1164.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
7.6 129.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
7.6 197.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
7.6 106.0 GO:0005642 annulate lamellae(GO:0005642)
7.4 37.2 GO:0043291 RAVE complex(GO:0043291)
7.4 37.2 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
7.4 96.1 GO:0042555 MCM complex(GO:0042555)
7.4 36.9 GO:0032449 CBM complex(GO:0032449)
7.3 29.3 GO:0048179 activin receptor complex(GO:0048179)
7.3 29.3 GO:0071159 NF-kappaB complex(GO:0071159)
7.3 14.6 GO:0030689 Noc complex(GO:0030689)
7.3 58.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
7.3 364.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
7.2 245.4 GO:0071564 npBAF complex(GO:0071564)
7.2 129.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
7.2 115.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
7.1 213.2 GO:0016469 proton-transporting two-sector ATPase complex(GO:0016469)
7.0 28.1 GO:0030905 retromer, tubulation complex(GO:0030905)
7.0 13.9 GO:1990423 RZZ complex(GO:1990423)
6.9 34.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
6.9 20.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
6.8 27.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
6.8 54.3 GO:0016600 flotillin complex(GO:0016600)
6.8 6.8 GO:0005899 insulin receptor complex(GO:0005899)
6.8 6.8 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
6.7 20.2 GO:0071821 FANCM-MHF complex(GO:0071821)
6.7 106.8 GO:0005641 nuclear envelope lumen(GO:0005641)
6.6 79.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
6.6 53.0 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
6.5 58.7 GO:0044666 MLL3/4 complex(GO:0044666)
6.5 1034.0 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
6.5 6.5 GO:0097342 ripoptosome(GO:0097342)
6.4 365.8 GO:0005876 spindle microtubule(GO:0005876)
6.3 25.2 GO:0046581 intercellular canaliculus(GO:0046581)
6.3 6.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
6.3 69.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
6.3 106.5 GO:0070822 Sin3-type complex(GO:0070822)
6.2 43.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
6.2 6.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
6.1 73.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
6.1 73.1 GO:0030008 TRAPP complex(GO:0030008)
6.0 6.0 GO:0005726 perichromatin fibrils(GO:0005726)
5.9 177.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
5.8 128.1 GO:0030056 hemidesmosome(GO:0030056)
5.8 40.4 GO:0097451 glial limiting end-foot(GO:0097451)
5.8 80.7 GO:0097431 mitotic spindle pole(GO:0097431)
5.7 34.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
5.7 164.8 GO:0005719 nuclear euchromatin(GO:0005719)
5.7 28.3 GO:0001940 male pronucleus(GO:0001940)
5.6 33.7 GO:0030014 CCR4-NOT complex(GO:0030014)
5.6 33.7 GO:1990357 terminal web(GO:1990357)
5.6 39.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
5.6 44.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
5.6 50.2 GO:0042612 MHC class I protein complex(GO:0042612)
5.6 61.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
5.5 481.9 GO:0000776 kinetochore(GO:0000776)
5.5 60.8 GO:0005638 lamin filament(GO:0005638)
5.5 60.6 GO:0097470 ribbon synapse(GO:0097470)
5.5 5.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
5.5 5.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
5.4 318.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
5.4 16.1 GO:0018444 translation release factor complex(GO:0018444)
5.3 21.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
5.3 47.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
5.3 99.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
5.2 62.7 GO:0000815 ESCRT III complex(GO:0000815)
5.2 119.3 GO:0030992 intraciliary transport particle B(GO:0030992)
5.1 15.4 GO:0033565 ESCRT-0 complex(GO:0033565)
5.1 25.6 GO:0030904 retromer complex(GO:0030904)
5.1 15.3 GO:0035517 PR-DUB complex(GO:0035517)
5.1 25.3 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
5.0 986.3 GO:0005681 spliceosomal complex(GO:0005681)
5.0 20.0 GO:0097452 GAIT complex(GO:0097452)
5.0 64.6 GO:0005662 DNA replication factor A complex(GO:0005662)
4.9 19.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
4.9 98.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
4.9 14.6 GO:0044611 nuclear pore inner ring(GO:0044611)
4.8 38.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
4.8 4.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
4.8 52.8 GO:0000124 SAGA complex(GO:0000124)
4.8 76.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
4.7 23.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
4.7 42.6 GO:0030127 COPII vesicle coat(GO:0030127)
4.7 150.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
4.7 435.5 GO:0035578 azurophil granule lumen(GO:0035578)
4.7 28.0 GO:0005955 calcineurin complex(GO:0005955)
4.6 2643.1 GO:0005925 focal adhesion(GO:0005925)
4.6 9.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
4.6 50.4 GO:0070449 elongin complex(GO:0070449)
4.6 27.4 GO:0005610 laminin-5 complex(GO:0005610)
4.5 13.5 GO:0070557 PCNA-p21 complex(GO:0070557)
4.5 17.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
4.4 39.8 GO:0072546 ER membrane protein complex(GO:0072546)
4.4 13.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
4.4 13.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
4.3 251.5 GO:0015934 large ribosomal subunit(GO:0015934)
4.3 4.3 GO:0032807 DNA ligase IV complex(GO:0032807)
4.2 20.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
4.2 166.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
4.1 28.4 GO:0097413 Lewy body(GO:0097413)
4.1 133.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
4.1 300.0 GO:0005811 lipid particle(GO:0005811)
4.1 32.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
4.0 28.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
4.0 32.3 GO:0070652 HAUS complex(GO:0070652)
4.0 16.2 GO:0005846 nuclear cap binding complex(GO:0005846)
4.0 12.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
3.9 51.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
3.9 31.2 GO:0031209 SCAR complex(GO:0031209)
3.9 23.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
3.8 15.0 GO:0044307 dendritic branch(GO:0044307)
3.7 18.7 GO:1902560 GMP reductase complex(GO:1902560)
3.7 22.1 GO:0070552 BRISC complex(GO:0070552)
3.7 43.8 GO:0042405 nuclear inclusion body(GO:0042405)
3.6 46.6 GO:0043073 germ cell nucleus(GO:0043073)
3.6 17.9 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
3.6 14.3 GO:0030891 VCB complex(GO:0030891)
3.5 24.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
3.5 21.0 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
3.5 35.0 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
3.5 7.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
3.5 299.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
3.5 10.4 GO:0002081 outer acrosomal membrane(GO:0002081)
3.4 27.6 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
3.4 6.8 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
3.4 23.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
3.3 26.7 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
3.3 3.3 GO:0005797 Golgi medial cisterna(GO:0005797)
3.2 81.2 GO:0031264 death-inducing signaling complex(GO:0031264)
3.2 6.5 GO:0070435 Shc-EGFR complex(GO:0070435)
3.2 61.1 GO:0044391 ribosomal subunit(GO:0044391)
3.2 112.5 GO:0043034 costamere(GO:0043034)
3.2 9.6 GO:0034457 Mpp10 complex(GO:0034457)
3.2 22.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
3.1 40.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
3.1 31.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
3.1 12.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
3.0 54.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
3.0 23.9 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
3.0 62.2 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
2.9 8.7 GO:1990393 3M complex(GO:1990393)
2.9 26.1 GO:0036020 endolysosome membrane(GO:0036020)
2.9 106.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
2.8 152.7 GO:0035580 specific granule lumen(GO:0035580)
2.8 19.7 GO:0008091 spectrin(GO:0008091)
2.8 22.4 GO:0070187 telosome(GO:0070187)
2.8 170.6 GO:0005643 nuclear pore(GO:0005643)
2.8 77.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
2.8 8.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
2.8 16.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
2.7 24.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
2.7 232.4 GO:0005913 cell-cell adherens junction(GO:0005913)
2.7 53.3 GO:0035861 site of double-strand break(GO:0035861)
2.7 39.9 GO:0070469 respiratory chain(GO:0070469)
2.6 13.2 GO:0001739 sex chromatin(GO:0001739)
2.6 37.0 GO:0000178 exosome (RNase complex)(GO:0000178)
2.6 576.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
2.6 5.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
2.6 5.2 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
2.6 118.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
2.5 2.5 GO:1990462 omegasome(GO:1990462)
2.5 17.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
2.5 2.5 GO:0031166 integral component of vacuolar membrane(GO:0031166)
2.5 2.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
2.5 22.2 GO:0051233 spindle midzone(GO:0051233)
2.5 12.3 GO:0032044 DSIF complex(GO:0032044)
2.4 63.7 GO:0000421 autophagosome membrane(GO:0000421)
2.4 2.4 GO:0043260 laminin-11 complex(GO:0043260)
2.4 19.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
2.4 77.1 GO:0005605 basal lamina(GO:0005605)
2.4 18.9 GO:1990909 Wnt signalosome(GO:1990909)
2.3 4.7 GO:0033186 CAF-1 complex(GO:0033186)
2.3 27.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
2.3 6.8 GO:0072557 IPAF inflammasome complex(GO:0072557)
2.3 20.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
2.2 6.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
2.2 8.9 GO:0031616 spindle pole centrosome(GO:0031616)
2.2 39.7 GO:0038201 TOR complex(GO:0038201)
2.2 70.4 GO:0008180 COP9 signalosome(GO:0008180)
2.2 91.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
2.2 95.6 GO:0005637 nuclear inner membrane(GO:0005637)
2.1 265.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
2.1 4.3 GO:0030125 clathrin vesicle coat(GO:0030125)
2.1 29.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
2.1 58.8 GO:0031526 brush border membrane(GO:0031526)
2.1 18.9 GO:0032059 bleb(GO:0032059)
2.1 31.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
2.1 26.8 GO:0000812 Swr1 complex(GO:0000812)
2.0 8.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
2.0 2.0 GO:0000805 X chromosome(GO:0000805)
1.9 9.7 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
1.9 11.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.9 514.7 GO:0005759 mitochondrial matrix(GO:0005759)
1.9 92.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.9 26.7 GO:0001891 phagocytic cup(GO:0001891)
1.9 19.0 GO:0070852 cell body fiber(GO:0070852)
1.9 5.6 GO:0005588 collagen type V trimer(GO:0005588)
1.8 14.8 GO:0030686 90S preribosome(GO:0030686)
1.8 7.3 GO:0035363 histone locus body(GO:0035363)
1.7 16.9 GO:0061574 ASAP complex(GO:0061574)
1.7 3.3 GO:0055087 Ski complex(GO:0055087)
1.6 4.9 GO:0000439 core TFIIH complex(GO:0000439)
1.6 50.3 GO:0032420 stereocilium(GO:0032420)
1.6 13.0 GO:0071203 WASH complex(GO:0071203)
1.6 22.6 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
1.6 16.1 GO:0036452 ESCRT complex(GO:0036452)
1.6 3.2 GO:0005869 dynactin complex(GO:0005869)
1.6 1.6 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
1.6 1.6 GO:0071920 cleavage body(GO:0071920)
1.5 109.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
1.5 7.6 GO:0005587 collagen type IV trimer(GO:0005587)
1.5 4.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.5 98.3 GO:0000793 condensed chromosome(GO:0000793)
1.5 43.2 GO:0045178 basal part of cell(GO:0045178)
1.5 7.3 GO:0010369 chromocenter(GO:0010369)
1.4 4.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.4 15.5 GO:0097346 INO80-type complex(GO:0097346)
1.4 7.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
1.4 2.8 GO:1902636 kinociliary basal body(GO:1902636)
1.4 2.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.4 8.2 GO:0032279 asymmetric synapse(GO:0032279)
1.3 1.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
1.3 14.7 GO:0032039 integrator complex(GO:0032039)
1.3 3286.5 GO:0070062 extracellular exosome(GO:0070062)
1.3 19.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
1.3 5.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.3 22.8 GO:0032432 actin filament bundle(GO:0032432)
1.3 2.5 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
1.2 52.6 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
1.2 17.4 GO:0031985 Golgi cisterna(GO:0031985)
1.1 117.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
1.1 4.5 GO:0016514 SWI/SNF complex(GO:0016514)
1.0 41.9 GO:0030496 midbody(GO:0030496)
1.0 6.7 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.9 4.6 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.9 9.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.9 16.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.8 4.7 GO:0002102 podosome(GO:0002102)
0.7 2.2 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.7 18.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.7 14.3 GO:0005861 troponin complex(GO:0005861)
0.7 4.6 GO:0032797 SMN complex(GO:0032797)
0.6 4.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.6 1.8 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.6 3.0 GO:0000346 transcription export complex(GO:0000346)
0.5 3.5 GO:0042641 actomyosin(GO:0042641)
0.5 2.9 GO:0032389 MutLalpha complex(GO:0032389)
0.5 13.4 GO:0072686 mitotic spindle(GO:0072686)
0.4 11.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.4 7.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4 0.7 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.4 2.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.3 0.7 GO:0070939 Dsl1p complex(GO:0070939)
0.3 32.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 1.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 1.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 1.6 GO:1990635 proximal dendrite(GO:1990635)
0.2 2.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 14.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.6 GO:0043196 varicosity(GO:0043196)
0.1 12.0 GO:0005819 spindle(GO:0005819)
0.1 0.3 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
43.2 345.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
39.9 119.7 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
38.1 114.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
36.5 109.6 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
36.0 108.0 GO:0098808 mRNA cap binding(GO:0098808)
35.9 143.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
35.3 176.4 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
34.4 103.2 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
34.0 136.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
33.7 168.5 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
32.9 164.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
31.7 95.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
31.1 93.3 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
30.1 150.6 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
29.6 207.1 GO:0061133 endopeptidase activator activity(GO:0061133)
28.7 86.2 GO:0004639 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
28.7 86.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
27.7 166.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
27.5 109.9 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
27.1 81.3 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
26.4 79.1 GO:0032767 copper-dependent protein binding(GO:0032767)
26.3 78.8 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
26.1 104.5 GO:0004802 transketolase activity(GO:0004802)
25.5 76.4 GO:0004132 dCMP deaminase activity(GO:0004132)
25.4 152.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
24.8 74.4 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
24.7 74.2 GO:0004766 spermidine synthase activity(GO:0004766)
24.6 98.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
24.3 146.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
24.3 72.9 GO:0030156 benzodiazepine receptor binding(GO:0030156)
24.2 72.7 GO:0004730 pseudouridylate synthase activity(GO:0004730)
24.1 72.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
23.6 94.5 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
22.5 67.4 GO:0005046 KDEL sequence binding(GO:0005046)
22.4 67.2 GO:0031403 lithium ion binding(GO:0031403)
22.3 156.1 GO:0032217 riboflavin transporter activity(GO:0032217)
22.1 88.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
22.0 88.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
21.9 131.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
21.8 65.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
21.6 172.9 GO:0015288 porin activity(GO:0015288)
21.4 149.7 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
21.4 64.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
20.9 62.7 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
20.8 62.5 GO:0031177 phosphopantetheine binding(GO:0031177)
20.8 62.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
20.8 290.7 GO:0031386 protein tag(GO:0031386)
20.7 62.2 GO:0009041 uridylate kinase activity(GO:0009041)
20.5 81.8 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
20.4 203.6 GO:0070883 pre-miRNA binding(GO:0070883)
20.3 81.2 GO:0002060 purine nucleobase binding(GO:0002060)
20.0 20.0 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
20.0 119.8 GO:0004594 pantothenate kinase activity(GO:0004594)
19.4 135.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
19.0 57.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
19.0 57.0 GO:0004170 dUTP diphosphatase activity(GO:0004170)
18.1 108.9 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
18.1 180.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
17.9 71.5 GO:0004743 pyruvate kinase activity(GO:0004743)
17.6 123.4 GO:0005497 androgen binding(GO:0005497)
17.6 123.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
17.5 227.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
17.3 104.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
17.3 69.3 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
17.3 51.9 GO:0010698 acetyltransferase activator activity(GO:0010698)
17.2 223.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
17.0 118.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
16.9 67.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
16.9 84.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
16.8 50.5 GO:0047012 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
16.6 66.4 GO:0004074 biliverdin reductase activity(GO:0004074)
16.6 66.4 GO:0004001 adenosine kinase activity(GO:0004001)
16.6 49.7 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
16.3 48.8 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
16.2 65.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
16.2 129.7 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
15.8 63.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
15.8 63.2 GO:0033677 DNA/RNA helicase activity(GO:0033677)
15.8 142.1 GO:1990226 histone methyltransferase binding(GO:1990226)
15.6 62.5 GO:0044388 small protein activating enzyme binding(GO:0044388)
15.5 93.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
15.5 46.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
15.2 60.7 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
14.7 411.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
14.7 161.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
14.6 87.7 GO:0004849 uridine kinase activity(GO:0004849)
14.6 102.2 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
14.6 58.4 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
14.5 72.7 GO:0042296 ISG15 transferase activity(GO:0042296)
14.4 14.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
14.3 42.8 GO:0004056 argininosuccinate lyase activity(GO:0004056)
14.2 71.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
14.1 56.5 GO:0043515 kinetochore binding(GO:0043515)
14.0 168.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
13.9 249.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
13.8 41.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
13.7 95.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
13.4 120.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
13.4 214.1 GO:0001054 RNA polymerase I activity(GO:0001054)
13.3 39.8 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
13.3 92.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
13.3 106.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
13.2 13.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
13.2 52.7 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
13.1 78.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
13.1 39.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
12.9 51.7 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
12.9 64.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
12.8 153.8 GO:0004526 ribonuclease P activity(GO:0004526)
12.8 38.3 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
12.7 51.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
12.6 352.6 GO:0017166 vinculin binding(GO:0017166)
12.6 50.2 GO:0003883 CTP synthase activity(GO:0003883)
12.4 37.3 GO:0004998 transferrin receptor activity(GO:0004998)
12.3 49.3 GO:0070513 death domain binding(GO:0070513)
12.3 12.3 GO:0000400 four-way junction DNA binding(GO:0000400)
12.2 49.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
12.2 48.9 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
12.1 72.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
12.0 59.9 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
12.0 47.8 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
11.9 23.9 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
11.9 47.6 GO:0070404 NADH binding(GO:0070404)
11.8 283.8 GO:0070628 proteasome binding(GO:0070628)
11.7 35.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
11.7 58.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
11.6 92.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
11.6 23.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
11.6 69.5 GO:0033592 RNA strand annealing activity(GO:0033592)
11.6 46.3 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
11.5 103.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
11.5 80.6 GO:0050815 phosphoserine binding(GO:0050815)
11.4 11.4 GO:0000104 succinate dehydrogenase activity(GO:0000104)
11.4 514.1 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
11.3 22.6 GO:0046979 TAP2 binding(GO:0046979)
11.3 79.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
11.2 33.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
11.2 101.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
11.0 44.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
10.9 283.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
10.9 65.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
10.9 10.9 GO:0016530 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
10.7 74.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
10.7 181.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
10.6 31.9 GO:0048030 disaccharide binding(GO:0048030)
10.6 31.9 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
10.5 31.4 GO:0070025 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
10.4 31.3 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
10.3 196.1 GO:0043495 protein anchor(GO:0043495)
10.3 61.8 GO:0016842 amidine-lyase activity(GO:0016842)
10.2 112.4 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
10.2 61.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
10.2 10.2 GO:0032404 mismatch repair complex binding(GO:0032404)
10.2 30.5 GO:0045131 pre-mRNA branch point binding(GO:0045131)
10.1 302.1 GO:0042288 MHC class I protein binding(GO:0042288)
10.1 20.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
9.9 39.7 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
9.9 29.7 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
9.7 58.0 GO:0016748 succinyltransferase activity(GO:0016748)
9.6 48.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
9.6 28.9 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
9.6 86.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
9.4 28.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
9.4 37.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
9.4 37.5 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
9.4 28.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
9.4 28.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
9.3 37.3 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
9.3 27.9 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
9.3 46.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
9.3 9.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
9.3 46.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
9.2 27.6 GO:1903135 cupric ion binding(GO:1903135)
9.1 128.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
9.1 81.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
9.0 117.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
9.0 9.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
9.0 17.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
9.0 62.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
8.9 35.6 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
8.8 43.9 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
8.8 26.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
8.8 8.8 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
8.8 26.3 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
8.7 96.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
8.7 87.2 GO:0042731 PH domain binding(GO:0042731)
8.6 25.9 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
8.6 222.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
8.5 221.3 GO:0070182 DNA polymerase binding(GO:0070182)
8.5 42.4 GO:0097617 annealing activity(GO:0097617)
8.4 33.8 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
8.4 75.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
8.4 16.8 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
8.3 8.3 GO:0045294 alpha-catenin binding(GO:0045294)
8.3 24.8 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
8.2 197.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
8.2 8.2 GO:0032810 sterol response element binding(GO:0032810)
8.2 24.6 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
8.1 32.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
8.0 47.9 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
7.9 31.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
7.9 47.5 GO:0004301 epoxide hydrolase activity(GO:0004301)
7.9 284.4 GO:0008143 poly(A) binding(GO:0008143)
7.9 31.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
7.8 595.4 GO:0019003 GDP binding(GO:0019003)
7.8 7.8 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
7.8 85.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
7.8 15.6 GO:0055100 adiponectin binding(GO:0055100)
7.8 31.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
7.8 38.9 GO:0032143 single thymine insertion binding(GO:0032143)
7.7 77.2 GO:0042301 phosphate ion binding(GO:0042301)
7.7 23.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
7.6 76.5 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
7.6 30.5 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
7.6 30.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
7.6 38.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
7.5 37.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
7.5 22.6 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
7.5 15.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
7.5 7.5 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
7.5 7.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
7.5 44.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
7.5 37.3 GO:1990460 leptin receptor binding(GO:1990460)
7.4 51.5 GO:0016403 dimethylargininase activity(GO:0016403)
7.3 29.4 GO:0030622 U4atac snRNA binding(GO:0030622)
7.3 117.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
7.3 44.0 GO:0005047 signal recognition particle binding(GO:0005047)
7.3 14.7 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
7.3 21.9 GO:0034511 U3 snoRNA binding(GO:0034511)
7.3 21.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
7.3 262.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
7.2 21.7 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
7.2 72.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
7.2 129.4 GO:0016018 cyclosporin A binding(GO:0016018)
7.1 21.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
7.1 7.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
7.1 85.1 GO:0001222 transcription corepressor binding(GO:0001222)
7.1 21.2 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
7.0 56.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
6.9 13.8 GO:0043398 HLH domain binding(GO:0043398)
6.9 41.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
6.9 55.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
6.9 27.5 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
6.9 6.9 GO:0046923 ER retention sequence binding(GO:0046923)
6.8 27.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
6.8 34.2 GO:0016936 galactoside binding(GO:0016936)
6.8 211.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
6.8 20.4 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
6.8 108.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
6.8 13.5 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
6.7 20.2 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
6.7 53.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
6.7 161.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
6.7 67.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
6.7 220.9 GO:0001671 ATPase activator activity(GO:0001671)
6.7 46.7 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
6.7 26.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) procollagen-proline dioxygenase activity(GO:0019798)
6.7 20.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
6.6 19.9 GO:0001069 regulatory region RNA binding(GO:0001069)
6.6 46.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
6.6 72.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
6.6 26.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
6.6 19.7 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
6.6 19.7 GO:0004528 phosphodiesterase I activity(GO:0004528)
6.5 32.6 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
6.5 103.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
6.5 77.8 GO:0000339 RNA cap binding(GO:0000339)
6.5 45.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
6.4 64.5 GO:0070087 chromo shadow domain binding(GO:0070087)
6.4 127.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
6.4 95.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
6.3 76.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
6.3 38.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
6.3 43.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
6.2 12.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
6.2 24.6 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
6.2 61.5 GO:0046527 glucosyltransferase activity(GO:0046527)
6.2 86.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
6.1 24.4 GO:0005163 nerve growth factor receptor binding(GO:0005163)
6.1 230.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
6.0 30.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
6.0 18.0 GO:0043035 chromatin insulator sequence binding(GO:0043035)
6.0 30.0 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
6.0 17.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
6.0 35.8 GO:0070569 uridylyltransferase activity(GO:0070569)
6.0 35.8 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
6.0 285.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
5.9 5.9 GO:0034046 poly(G) binding(GO:0034046)
5.9 1240.1 GO:0003735 structural constituent of ribosome(GO:0003735)
5.9 29.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
5.8 46.5 GO:0050733 RS domain binding(GO:0050733)
5.8 340.2 GO:0003743 translation initiation factor activity(GO:0003743)
5.7 28.7 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
5.7 51.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
5.7 103.3 GO:0035497 cAMP response element binding(GO:0035497)
5.7 108.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
5.7 11.4 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
5.7 11.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
5.7 39.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
5.7 272.5 GO:0050699 WW domain binding(GO:0050699)
5.7 5.7 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
5.6 107.3 GO:0031369 translation initiation factor binding(GO:0031369)
5.6 45.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
5.6 22.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
5.6 50.4 GO:0089720 caspase binding(GO:0089720)
5.6 16.7 GO:0004566 beta-glucuronidase activity(GO:0004566)
5.6 166.9 GO:0070410 co-SMAD binding(GO:0070410)
5.6 5.6 GO:0032427 GBD domain binding(GO:0032427)
5.5 44.1 GO:0001055 RNA polymerase II activity(GO:0001055)
5.5 2177.7 GO:0045296 cadherin binding(GO:0045296)
5.4 16.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
5.4 16.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
5.4 32.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
5.3 96.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
5.3 37.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
5.3 79.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
5.3 84.7 GO:0097602 cullin family protein binding(GO:0097602)
5.3 21.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
5.2 21.0 GO:0035500 MH2 domain binding(GO:0035500)
5.2 31.3 GO:0070878 primary miRNA binding(GO:0070878)
5.2 161.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
5.2 83.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
5.2 5.2 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
5.1 15.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
5.1 51.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
5.1 41.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
5.1 56.3 GO:0019534 toxin transporter activity(GO:0019534)
5.1 101.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
5.1 5.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
5.1 50.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
5.1 30.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
5.0 20.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
5.0 105.6 GO:0070064 proline-rich region binding(GO:0070064)
5.0 140.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
5.0 75.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
5.0 15.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
5.0 49.9 GO:0050692 DBD domain binding(GO:0050692)
5.0 14.9 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
5.0 119.4 GO:0017025 TBP-class protein binding(GO:0017025)
5.0 119.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
5.0 24.9 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
4.9 123.4 GO:0051059 NF-kappaB binding(GO:0051059)
4.9 4.9 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
4.9 29.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
4.9 24.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
4.9 53.4 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
4.8 28.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
4.8 9.6 GO:0070324 thyroid hormone binding(GO:0070324)
4.8 28.5 GO:0030620 U2 snRNA binding(GO:0030620)
4.8 104.5 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
4.7 18.9 GO:0036033 mediator complex binding(GO:0036033)
4.7 18.8 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
4.7 18.8 GO:0004335 galactokinase activity(GO:0004335)
4.7 14.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
4.7 23.3 GO:0019776 Atg8 ligase activity(GO:0019776)
4.7 14.0 GO:0008097 5S rRNA binding(GO:0008097)
4.6 4.6 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
4.6 32.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
4.6 4.6 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
4.6 55.1 GO:0003688 DNA replication origin binding(GO:0003688)
4.6 36.7 GO:0042609 CD4 receptor binding(GO:0042609)
4.6 4.6 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
4.5 95.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
4.5 8.9 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
4.5 26.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
4.5 8.9 GO:0070717 poly-purine tract binding(GO:0070717)
4.4 39.9 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
4.4 8.8 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
4.4 39.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
4.4 13.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
4.4 17.4 GO:0051879 Hsp90 protein binding(GO:0051879)
4.3 12.8 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
4.3 59.6 GO:0031489 myosin V binding(GO:0031489)
4.2 21.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
4.2 105.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
4.2 12.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
4.2 25.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
4.2 16.7 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
4.1 82.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
4.1 28.7 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
4.1 12.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
4.1 8.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
4.1 77.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
4.0 12.1 GO:0003896 DNA primase activity(GO:0003896)
4.0 20.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
4.0 123.5 GO:0005123 death receptor binding(GO:0005123)
4.0 55.3 GO:0008301 DNA binding, bending(GO:0008301)
3.9 15.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
3.9 3.9 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
3.9 62.7 GO:0003746 translation elongation factor activity(GO:0003746)
3.9 38.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
3.8 23.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
3.8 3.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
3.8 19.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
3.8 11.5 GO:0032089 NACHT domain binding(GO:0032089)
3.8 15.1 GO:0070990 snRNP binding(GO:0070990)
3.7 11.2 GO:0031626 beta-endorphin binding(GO:0031626)
3.7 18.7 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
3.7 33.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
3.7 18.6 GO:0097100 supercoiled DNA binding(GO:0097100)
3.7 7.4 GO:0017089 glycolipid transporter activity(GO:0017089)
3.7 11.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
3.7 14.8 GO:0008641 small protein activating enzyme activity(GO:0008641)
3.7 102.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
3.7 29.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
3.6 21.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
3.6 57.3 GO:0008179 adenylate cyclase binding(GO:0008179)
3.6 42.9 GO:0017049 GTP-Rho binding(GO:0017049)
3.6 10.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
3.5 46.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
3.5 17.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
3.5 70.3 GO:0008536 Ran GTPase binding(GO:0008536)
3.5 10.4 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
3.5 27.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
3.4 27.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
3.4 488.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
3.4 27.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
3.4 57.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
3.4 13.6 GO:0033897 ribonuclease T2 activity(GO:0033897)
3.4 16.9 GO:0097016 L27 domain binding(GO:0097016)
3.4 50.4 GO:0017070 U6 snRNA binding(GO:0017070)
3.4 107.6 GO:0043236 laminin binding(GO:0043236)
3.3 23.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
3.3 66.0 GO:0048156 tau protein binding(GO:0048156)
3.3 39.6 GO:0050786 RAGE receptor binding(GO:0050786)
3.3 19.7 GO:0019237 centromeric DNA binding(GO:0019237)
3.3 72.1 GO:0008242 omega peptidase activity(GO:0008242)
3.3 39.3 GO:0032036 myosin heavy chain binding(GO:0032036)
3.3 3.3 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
3.2 61.5 GO:0051400 BH domain binding(GO:0051400)
3.2 41.1 GO:0031491 nucleosome binding(GO:0031491)
3.2 15.8 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
3.2 3.2 GO:0015616 DNA translocase activity(GO:0015616)
3.1 31.2 GO:0043295 glutathione binding(GO:0043295)
3.1 9.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
3.1 3.1 GO:0016778 diphosphotransferase activity(GO:0016778)
3.1 12.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
3.1 12.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
3.0 12.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
3.0 12.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
3.0 12.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
3.0 33.3 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
3.0 60.4 GO:0003785 actin monomer binding(GO:0003785)
3.0 6.0 GO:0048256 flap endonuclease activity(GO:0048256)
3.0 104.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
3.0 47.7 GO:0008483 transaminase activity(GO:0008483)
3.0 305.7 GO:0043130 ubiquitin binding(GO:0043130)
3.0 26.7 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
3.0 50.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
2.9 14.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
2.9 26.4 GO:0019206 nucleoside kinase activity(GO:0019206)
2.9 2.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
2.9 55.6 GO:0005523 tropomyosin binding(GO:0005523)
2.9 84.1 GO:0015485 cholesterol binding(GO:0015485)
2.9 11.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.9 11.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
2.9 5.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
2.9 8.6 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
2.9 20.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
2.9 11.5 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
2.9 17.2 GO:0016361 activin receptor activity, type I(GO:0016361)
2.8 2.8 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
2.8 11.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
2.8 2.8 GO:0016979 lipoate-protein ligase activity(GO:0016979)
2.7 2.7 GO:0042608 T cell receptor binding(GO:0042608)
2.7 10.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
2.7 27.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
2.7 24.0 GO:0050700 CARD domain binding(GO:0050700)
2.7 10.7 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
2.6 15.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
2.6 13.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
2.6 13.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
2.6 23.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
2.6 33.5 GO:0035173 histone kinase activity(GO:0035173)
2.6 46.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
2.6 7.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
2.6 10.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
2.5 374.7 GO:0042393 histone binding(GO:0042393)
2.5 10.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
2.5 175.4 GO:0009055 electron carrier activity(GO:0009055)
2.5 27.7 GO:0017154 semaphorin receptor activity(GO:0017154)
2.5 379.1 GO:0005178 integrin binding(GO:0005178)
2.4 12.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
2.4 2.4 GO:0008169 C-methyltransferase activity(GO:0008169)
2.4 16.7 GO:0000182 rDNA binding(GO:0000182)
2.4 14.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
2.4 38.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
2.4 11.9 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
2.4 4.7 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
2.4 2.4 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
2.4 35.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.3 35.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
2.3 14.0 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
2.3 60.2 GO:0015248 sterol transporter activity(GO:0015248)
2.3 13.9 GO:0032190 acrosin binding(GO:0032190)
2.3 11.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
2.3 9.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
2.3 6.8 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
2.2 26.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
2.2 9.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
2.2 44.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
2.2 8.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
2.2 59.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
2.2 6.6 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
2.2 33.1 GO:0008432 JUN kinase binding(GO:0008432)
2.2 147.8 GO:0008565 protein transporter activity(GO:0008565)
2.2 8.8 GO:0004348 glucosylceramidase activity(GO:0004348)
2.2 8.8 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
2.2 17.6 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
2.2 24.1 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
2.2 8.6 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
2.2 15.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
2.1 27.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
2.1 10.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
2.1 6.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
2.1 6.4 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
2.1 6.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
2.0 10.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
2.0 4.1 GO:0004104 cholinesterase activity(GO:0004104)
2.0 47.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
2.0 109.0 GO:0008307 structural constituent of muscle(GO:0008307)
2.0 10.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
2.0 14.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
2.0 21.9 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
2.0 2.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
2.0 9.9 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
2.0 73.2 GO:0050681 androgen receptor binding(GO:0050681)
1.9 44.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
1.9 7.8 GO:0048408 epidermal growth factor binding(GO:0048408)
1.9 21.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
1.9 3.8 GO:0003678 DNA helicase activity(GO:0003678)
1.9 7.7 GO:0017018 myosin phosphatase activity(GO:0017018)
1.9 28.3 GO:0045295 gamma-catenin binding(GO:0045295)
1.9 5.6 GO:0015556 malate transmembrane transporter activity(GO:0015140) C4-dicarboxylate transmembrane transporter activity(GO:0015556)
1.9 9.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
1.9 5.6 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
1.9 22.5 GO:0030515 snoRNA binding(GO:0030515)
1.9 227.8 GO:0047485 protein N-terminus binding(GO:0047485)
1.9 7.4 GO:0015307 drug:proton antiporter activity(GO:0015307)
1.9 7.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
1.9 1.9 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
1.8 57.9 GO:0016831 carboxy-lyase activity(GO:0016831)
1.8 7.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.8 9.0 GO:0004905 type I interferon receptor activity(GO:0004905)
1.8 116.7 GO:0004177 aminopeptidase activity(GO:0004177)
1.8 46.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
1.8 5.4 GO:0002046 opsin binding(GO:0002046)
1.8 14.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
1.7 15.7 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.7 5.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.7 15.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
1.7 6.9 GO:0047685 amine sulfotransferase activity(GO:0047685)
1.7 10.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
1.7 8.5 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
1.7 3.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
1.7 5.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
1.7 3.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
1.7 43.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
1.6 3.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
1.6 116.6 GO:0051082 unfolded protein binding(GO:0051082)
1.6 30.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
1.6 9.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
1.6 35.5 GO:0042169 SH2 domain binding(GO:0042169)
1.6 9.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.6 11.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
1.6 9.6 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
1.6 3.2 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
1.6 9.5 GO:0004064 arylesterase activity(GO:0004064)
1.6 15.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.5 12.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
1.5 58.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
1.5 12.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.5 7.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
1.5 25.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
1.5 55.1 GO:0004407 histone deacetylase activity(GO:0004407)
1.5 14.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.5 30.8 GO:0071889 14-3-3 protein binding(GO:0071889)
1.5 109.8 GO:0003697 single-stranded DNA binding(GO:0003697)
1.5 18.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
1.4 11.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
1.4 15.7 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
1.4 7.1 GO:0004771 sterol esterase activity(GO:0004771)
1.4 14.2 GO:0001727 lipid kinase activity(GO:0001727)
1.4 4.3 GO:0004958 prostaglandin F receptor activity(GO:0004958)
1.4 9.9 GO:0016783 sulfurtransferase activity(GO:0016783)
1.4 8.4 GO:0004046 aminoacylase activity(GO:0004046)
1.4 85.0 GO:0032947 protein complex scaffold(GO:0032947)
1.4 19.1 GO:0070034 telomerase RNA binding(GO:0070034)
1.4 5.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.3 2.7 GO:0035473 lipase binding(GO:0035473)
1.3 18.5 GO:0016805 dipeptidase activity(GO:0016805)
1.3 5.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
1.3 7.9 GO:0030274 LIM domain binding(GO:0030274)
1.3 64.9 GO:0070888 E-box binding(GO:0070888)
1.3 14.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.3 3.9 GO:0046848 hydroxyapatite binding(GO:0046848)
1.3 25.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
1.3 20.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
1.3 5.1 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
1.3 3.8 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
1.3 8.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.3 30.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.2 7.5 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
1.2 5.0 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
1.2 69.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
1.2 8.5 GO:0016421 CoA carboxylase activity(GO:0016421)
1.2 25.2 GO:0000049 tRNA binding(GO:0000049)
1.2 10.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.2 13.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.2 2.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.1 5.7 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
1.1 5.6 GO:0035613 RNA stem-loop binding(GO:0035613)
1.1 8.9 GO:0008494 translation activator activity(GO:0008494)
1.1 479.3 GO:0003712 transcription cofactor activity(GO:0003712)
1.1 15.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
1.1 13.7 GO:0005212 structural constituent of eye lens(GO:0005212)
1.0 33.5 GO:0030332 cyclin binding(GO:0030332)
1.0 97.0 GO:0002020 protease binding(GO:0002020)
1.0 1.0 GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
1.0 21.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
1.0 10.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.0 100.1 GO:0051015 actin filament binding(GO:0051015)
1.0 2.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
1.0 4.9 GO:0019966 interleukin-1 binding(GO:0019966)
0.9 6.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.9 3.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.9 5.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.9 8.1 GO:0034452 dynactin binding(GO:0034452)
0.9 2.7 GO:0070984 SET domain binding(GO:0070984)
0.9 42.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.9 11.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.9 2.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.8 34.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.8 1.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.8 4.1 GO:0050544 icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.8 3.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.8 50.7 GO:0005518 collagen binding(GO:0005518)
0.8 6.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.8 49.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.8 26.0 GO:0005507 copper ion binding(GO:0005507)
0.8 19.8 GO:0071617 lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.8 5.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.7 123.3 GO:0003924 GTPase activity(GO:0003924)
0.7 15.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.7 3.6 GO:0046870 cadmium ion binding(GO:0046870)
0.7 2.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.7 7.7 GO:0031404 chloride ion binding(GO:0031404)
0.7 5.5 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.7 4.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.7 12.0 GO:0019239 deaminase activity(GO:0019239)
0.6 632.3 GO:0003723 RNA binding(GO:0003723)
0.6 7.7 GO:0004697 protein kinase C activity(GO:0004697)
0.6 3.8 GO:0015245 fatty acid transporter activity(GO:0015245)
0.6 10.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.6 4.0 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.6 6.7 GO:0009881 photoreceptor activity(GO:0009881)
0.5 2.2 GO:0016015 morphogen activity(GO:0016015)
0.5 1.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 3.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.5 1.5 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.5 4.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.5 1.0 GO:0038181 bile acid receptor activity(GO:0038181) vitamin D response element binding(GO:0070644)
0.4 1.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 2.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.4 1.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.4 3.0 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.4 1.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.4 1.7 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.4 0.8 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 1.4 GO:0044548 S100 protein binding(GO:0044548)
0.3 0.6 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 3.7 GO:0048018 receptor agonist activity(GO:0048018)
0.3 2.9 GO:0048019 receptor antagonist activity(GO:0048019)
0.3 0.5 GO:0036505 prosaposin receptor activity(GO:0036505)
0.3 7.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 2.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.5 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 0.9 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 9.4 GO:0008238 exopeptidase activity(GO:0008238)
0.2 1.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 2.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.5 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 18.3 GO:0008201 heparin binding(GO:0008201)
0.1 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 1.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 16.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 0.7 GO:0005549 odorant binding(GO:0005549)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
12.8 25.7 PID IFNG PATHWAY IFN-gamma pathway
11.2 1610.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
10.9 142.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
9.9 463.6 PID BARD1 PATHWAY BARD1 signaling events
9.3 509.5 PID AURORA B PATHWAY Aurora B signaling
8.9 241.3 PID ARF 3PATHWAY Arf1 pathway
8.9 204.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
8.7 286.1 PID ATM PATHWAY ATM pathway
8.3 382.5 PID PLK1 PATHWAY PLK1 signaling events
8.0 344.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
7.9 15.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
7.8 504.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
7.6 341.6 PID ATR PATHWAY ATR signaling pathway
7.3 88.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
7.1 353.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
6.8 75.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
6.6 91.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
6.1 12.2 PID S1P S1P1 PATHWAY S1P1 pathway
6.0 95.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
5.8 163.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
5.4 391.7 PID RAC1 PATHWAY RAC1 signaling pathway
5.1 154.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
5.1 35.7 PID WNT SIGNALING PATHWAY Wnt signaling network
5.0 423.8 PID E2F PATHWAY E2F transcription factor network
4.9 281.7 PID ILK PATHWAY Integrin-linked kinase signaling
4.8 189.1 PID ALK1 PATHWAY ALK1 signaling events
4.8 135.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
4.4 88.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
4.2 83.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
4.1 114.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
4.0 112.3 PID RHOA PATHWAY RhoA signaling pathway
4.0 108.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
4.0 47.5 PID FANCONI PATHWAY Fanconi anemia pathway
3.6 7.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
3.6 233.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
3.5 191.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
3.3 259.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
3.3 168.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
3.2 167.9 PID TGFBR PATHWAY TGF-beta receptor signaling
3.2 119.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
3.1 81.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
3.1 31.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
3.1 298.7 PID AR PATHWAY Coregulation of Androgen receptor activity
3.1 94.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
3.0 99.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
3.0 117.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
3.0 89.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
2.9 55.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
2.9 20.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
2.7 83.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
2.6 10.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
2.4 24.3 PID GLYPICAN 1PATHWAY Glypican 1 network
2.4 131.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
2.4 78.7 PID IL6 7 PATHWAY IL6-mediated signaling events
2.4 40.4 PID IGF1 PATHWAY IGF1 pathway
2.3 37.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
2.3 69.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
2.1 106.9 PID TELOMERASE PATHWAY Regulation of Telomerase
2.0 18.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
2.0 46.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
2.0 28.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
2.0 19.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
2.0 80.5 PID MTOR 4PATHWAY mTOR signaling pathway
1.9 44.7 PID FOXO PATHWAY FoxO family signaling
1.9 24.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
1.9 110.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
1.9 18.6 PID FAS PATHWAY FAS (CD95) signaling pathway
1.8 108.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.8 70.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
1.7 16.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
1.6 6.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
1.6 23.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
1.5 6.1 ST JAK STAT PATHWAY Jak-STAT Pathway
1.5 43.4 PID P53 REGULATION PATHWAY p53 pathway
1.4 35.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
1.4 19.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
1.4 61.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
1.2 15.8 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
1.1 10.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
1.1 85.0 PID CMYB PATHWAY C-MYB transcription factor network
1.0 6.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.9 1.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.8 36.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.8 19.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.7 22.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.7 7.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.7 4.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.6 19.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.6 4.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.5 11.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.5 1.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.5 8.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.4 33.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.4 4.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.4 16.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.3 4.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.3 7.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.3 2.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.3 5.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 50.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 2.0 PID AURORA A PATHWAY Aurora A signaling
0.2 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.2 2.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.9 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
18.4 590.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
18.4 276.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
17.3 260.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
16.3 538.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
16.0 240.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
15.4 1121.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
15.3 214.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
14.5 72.6 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
14.5 159.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
14.3 214.3 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
14.2 227.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
14.1 212.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
13.9 457.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
13.6 313.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
13.6 544.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
13.4 227.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
13.2 144.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
12.9 296.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
12.9 51.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
12.5 350.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
12.2 415.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
12.0 108.3 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
11.5 311.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
11.4 22.8 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
11.3 101.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
11.0 175.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
10.7 406.8 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
10.5 73.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
10.4 595.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
10.3 61.9 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
10.3 349.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
10.3 235.8 REACTOME S PHASE Genes involved in S Phase
10.0 140.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
10.0 249.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
9.6 538.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
9.5 152.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
9.4 234.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
9.4 37.5 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
9.3 83.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
9.2 203.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
9.2 91.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
9.0 189.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
9.0 278.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
8.9 133.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
8.8 211.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
8.6 43.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
8.4 185.2 REACTOME METABOLISM OF NUCLEOTIDES Genes involved in Metabolism of nucleotides
8.2 156.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
8.1 169.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
8.1 153.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
7.9 206.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
7.9 134.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
7.9 363.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
7.9 276.0 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
7.4 66.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
7.1 538.7 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
7.0 365.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
7.0 7.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
6.9 358.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
6.3 57.0 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
6.3 500.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
6.3 151.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
6.1 128.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
6.0 180.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
5.9 148.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
5.9 99.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
5.9 258.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
5.8 279.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
5.6 423.6 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
5.5 136.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
5.4 637.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
5.4 48.4 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
5.2 88.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
5.2 62.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
5.2 154.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
5.1 86.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
5.1 71.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
5.0 60.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
5.0 95.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
5.0 341.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
4.9 59.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
4.9 117.1 REACTOME TRANSLATION Genes involved in Translation
4.7 142.0 REACTOME NUCLEOTIDE EXCISION REPAIR Genes involved in Nucleotide Excision Repair
4.7 84.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
4.7 79.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
4.6 473.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
4.6 110.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
4.6 36.9 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
4.6 252.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
4.5 58.9 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
4.4 505.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
4.4 104.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
4.0 606.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
3.9 93.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
3.8 98.6 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
3.8 49.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
3.8 7.5 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
3.8 154.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
3.7 51.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
3.7 47.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
3.5 102.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
3.5 14.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
3.5 69.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
3.5 58.9 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
3.5 62.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
3.4 17.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
3.4 78.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
3.4 37.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
3.3 36.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
3.3 26.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
3.1 58.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
3.1 97.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
3.0 94.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
2.9 34.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
2.9 65.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
2.8 79.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
2.8 36.5 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
2.8 5.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
2.8 22.4 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
2.8 50.2 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
2.8 93.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
2.7 89.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
2.6 54.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
2.6 5.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
2.5 47.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
2.4 4.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
2.4 98.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
2.3 65.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
2.3 36.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
2.2 35.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
2.2 25.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
2.1 31.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
2.0 40.0 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
2.0 19.6 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
1.9 41.4 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
1.8 27.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
1.8 17.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
1.8 65.8 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
1.8 136.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
1.7 8.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
1.7 24.3 REACTOME METABOLISM OF RNA Genes involved in Metabolism of RNA
1.6 16.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
1.6 16.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.6 44.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
1.6 21.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
1.6 25.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
1.5 4.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
1.5 28.9 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
1.5 97.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
1.4 89.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
1.4 98.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
1.4 32.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.4 40.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
1.3 26.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.2 8.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
1.1 36.9 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
1.1 20.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.0 24.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
1.0 15.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
1.0 5.0 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
1.0 2.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
1.0 3.9 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
1.0 49.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.9 14.6 REACTOME KINESINS Genes involved in Kinesins
0.8 11.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.8 5.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.8 98.0 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.8 4.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.7 1.4 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.7 1.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.7 12.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.7 2.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.6 12.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.6 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.6 9.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.6 3.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.5 41.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.5 11.6 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.4 4.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 2.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.3 25.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.3 2.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2 1.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 2.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 21.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 2.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 22.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 4.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 19.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 1.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 6.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.8 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation