avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SPDEF Links Ensembl NCBI GeneCards UniProt	ENSG00000124664.11	SPDEF

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SPDEF	hg38_v1_chr6_-_34556319_34556339	-0.43	4.0e-11	Click!

View svg image
View png image

Promoter	Score	Transcript	Gene	Gene Info
chr2_+_161308407 Show fit	34.34	ENST00000409682.8	PSMD14 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 14
chr12_-_102120065 Show fit	31.79	ENST00000552283.6 ENST00000551744.2	NUP37 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 37
chr14_-_24146596 Show fit	29.66	ENST00000560410.5 ENST00000216802.10 ENST00000615264.4 ENST00000630027.1	PSME2 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome activator subunit 2
chr17_-_64662290 Show fit	27.16	ENST00000262435.14	SMURF2 Links Ensembl NCBI GeneCards UniProt Show fit	SMAD specific E3 ubiquitin protein ligase 2
chr15_-_59657468 Show fit	26.14	ENST00000396061.5	GTF2A2 Links Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIA subunit 2
chr1_+_84479239 Show fit	26.10	ENST00000370656.5 ENST00000370654.6	RPF1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosome production factor 1 homolog
chr15_-_59657494 Show fit	26.09	ENST00000396063.5 ENST00000396060.7 ENST00000396064.7 ENST00000484743.5 ENST00000559706.1	GTF2A2 Links Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIA subunit 2
chr1_-_43172504 Show fit	25.86	ENST00000431635.6	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt Show fit	EBNA1 binding protein 2
chr2_+_197515565 Show fit	24.69	ENST00000233892.8 ENST00000409916.5	MOB4 Links Ensembl NCBI GeneCards UniProt Show fit	MOB family member 4, phocein
chr1_-_43172244 Show fit	24.36	ENST00000236051.3	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt Show fit	EBNA1 binding protein 2
chr1_-_67430320 Show fit	24.09	ENST00000370990.5	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr14_-_63543328 Show fit	23.73	ENST00000337537.8	PPP2R5E Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit B'epsilon
chr1_+_193060034 Show fit	23.25	ENST00000367446.7 ENST00000367443.5 ENST00000367444.7 ENST00000367445.7	RO60 Links Ensembl NCBI GeneCards UniProt Show fit	Ro60, Y RNA binding protein
chr5_+_892844 Show fit	22.54	ENST00000166345.8	TRIP13 Links Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor interactor 13
chr5_+_110738983 Show fit	21.83	ENST00000355943.8 ENST00000447245.6	SLC25A46 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 46
chr3_-_133661896 Show fit	21.31	ENST00000260810.10	TOPBP1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA topoisomerase II binding protein 1
chrX_+_47193796 Show fit	21.19	ENST00000442035.5 ENST00000335972.11 ENST00000457753.5	UBA1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin like modifier activating enzyme 1
chr1_-_67430386 Show fit	21.02	ENST00000370995.6 ENST00000361219.11	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr1_-_67430412 Show fit	21.00	ENST00000370994.8	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr2_+_197516039 Show fit	20.99	ENST00000448447.6 ENST00000323303.9 ENST00000409360.1	MOB4 Links Ensembl NCBI GeneCards UniProt Show fit	MOB family member 4, phocein
chr1_-_193059489 Show fit	20.93	ENST00000367455.8 ENST00000421683.1	UCHL5 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin C-terminal hydrolase L5
chrX_-_136880715 Show fit	20.85	ENST00000431446.7 ENST00000320676.11 ENST00000562646.5	RBMX Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein X-linked
chr1_+_109548567 Show fit	20.73	ENST00000369851.7	GNAI3 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha i3
chr14_+_35292374 Show fit	20.64	ENST00000261479.9 ENST00000553809.5	PSMA6 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 6
chr14_+_74881887 Show fit	19.93	ENST00000334220.9 ENST00000626051.1 ENST00000554806.5	DLST Links Ensembl NCBI GeneCards UniProt Show fit	dihydrolipoamide S-succinyltransferase
chr14_-_22589157 Show fit	19.66	ENST00000538631.1 ENST00000543337.1 ENST00000250498.9	DAD1 Links Ensembl NCBI GeneCards UniProt Show fit	defender against cell death 1
chr14_-_67359769 Show fit	19.63	ENST00000555431.5 ENST00000554236.5 ENST00000555474.5 ENST00000216442.12	ATP6V1D Links Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting V1 subunit D
chr15_-_63157464 Show fit	18.16	ENST00000330964.10 ENST00000635699.1 ENST00000439025.1	RPS27L Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S27 like
chr8_-_100952918 Show fit	18.11	ENST00000395957.6 ENST00000395948.6 ENST00000457309.2	YWHAZ Links Ensembl NCBI GeneCards UniProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr14_-_21383989 Show fit	17.93	ENST00000216297.7	SUPT16H Links Ensembl NCBI GeneCards UniProt Show fit	SPT16 homolog, facilitates chromatin remodeling subunit
chr14_+_35292308 Show fit	17.87	ENST00000628955.1 ENST00000627895.2 ENST00000622405.4	PSMA6 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 6
chr6_+_133953210 Show fit	17.63	ENST00000367869.1 ENST00000237264.9 ENST00000674115.1	TBPL1 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000288529.1 Links Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein like 1 novel protein
chr8_-_116755784 Show fit	17.63	ENST00000518949.5 ENST00000522453.1 ENST00000518995.5 ENST00000521861.6 ENST00000611080.1	EIF3H Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit H
chr2_+_65227792 Show fit	17.45	ENST00000260641.10 ENST00000377982.8	ACTR2 Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2
chr15_-_64989894 Show fit	17.34	ENST00000416889.6 ENST00000204566.7	SPG21 Links Ensembl NCBI GeneCards UniProt Show fit	SPG21 abhydrolase domain containing, maspardin
chr14_+_35292429 Show fit	17.15	ENST00000555764.5 ENST00000556506.1	PSMA6 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 6
chr1_-_65067707 Show fit	17.14	ENST00000672099.1 ENST00000671954.1 ENST00000672434.1 ENST00000673502.1 ENST00000672751.1	JAK1 Links Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 1
chr11_-_72112750 Show fit	17.09	ENST00000545680.5 ENST00000543587.5 ENST00000538393.5 ENST00000535234.5 ENST00000227618.8 ENST00000535503.5	ANAPC15 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr14_-_24146314 Show fit	17.06	ENST00000559056.5	PSME2 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome activator subunit 2
chrX_+_70290077 Show fit	16.96	ENST00000374403.4	KIF4A Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 4A
chr1_-_193059296 Show fit	16.91	ENST00000367450.7 ENST00000367451.8 ENST00000367454.6 ENST00000367448.5 ENST00000367449.5	UCHL5 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin C-terminal hydrolase L5
chr5_-_31532039 Show fit	16.68	ENST00000511367.6 ENST00000344624.8 ENST00000513349.5	DROSHA Links Ensembl NCBI GeneCards UniProt Show fit	drosha ribonuclease III
chr8_-_129939872 Show fit	16.40	ENST00000519540.5	CYRIB Links Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr20_-_2470749 Show fit	16.09	ENST00000381342.7 ENST00000438552.6	SNRPB Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptides B and B1
chr12_-_120581361 Show fit	16.02	ENST00000341039.6 ENST00000357500.5	POP5 Links Ensembl NCBI GeneCards UniProt Show fit	POP5 homolog, ribonuclease P/MRP subunit
chr8_-_129939694 Show fit	15.96	ENST00000522250.5 ENST00000522941.5 ENST00000522746.5 ENST00000520204.5 ENST00000519070.5 ENST00000520254.5 ENST00000519824.6	CYRIB Links Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr1_-_19485502 Show fit	15.94	ENST00000264203.7 ENST00000375144.6 ENST00000674432.1 ENST00000264202.8	CAPZB Links Ensembl NCBI GeneCards UniProt Show fit	capping actin protein of muscle Z-line subunit beta
chr10_-_119080794 Show fit	15.49	ENST00000369144.8 ENST00000541549.2	EIF3A Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit A
chr14_-_21269451 Show fit	15.43	ENST00000336053.10	HNRNPC Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein C
chr14_+_60249191 Show fit	15.27	ENST00000395076.9	PPM1A Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1A
chr7_+_99325857 Show fit	14.73	ENST00000638617.1 ENST00000262942.10	ENSG00000284292.1 Links Ensembl NCBI GeneCards UniProt Show fit ARPC1A Links Ensembl NCBI GeneCards UniProt Show fit	novel protein, ARPC1A and ARPC1B readthrough actin related protein 2/3 complex subunit 1A
chr22_+_43955424 Show fit	14.60	ENST00000350028.5	SAMM50 Links Ensembl NCBI GeneCards UniProt Show fit	SAMM50 sorting and assembly machinery component
chr14_-_21269392 Show fit	14.47	ENST00000554891.5 ENST00000555883.5 ENST00000553753.5 ENST00000555914.5 ENST00000557336.1 ENST00000555215.5 ENST00000556628.5 ENST00000555137.5 ENST00000556226.5 ENST00000555309.5 ENST00000556142.5 ENST00000554969.5 ENST00000554455.5 ENST00000556513.5 ENST00000557201.5 ENST00000420743.6 ENST00000557768.1 ENST00000553300.6 ENST00000554383.5 ENST00000554539.5	HNRNPC Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein C
chr5_+_87268922 Show fit	14.44	ENST00000456692.6 ENST00000512763.5 ENST00000506290.1	RASA1 Links Ensembl NCBI GeneCards UniProt Show fit	RAS p21 protein activator 1
chr11_-_72112669 Show fit	14.36	ENST00000545944.5 ENST00000502597.2	ANAPC15 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr1_-_235161215 Show fit	14.33	ENST00000447801.5 ENST00000408888.8 ENST00000429912.1	RBM34 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 34
chr3_-_31981228 Show fit	14.06	ENST00000396556.7 ENST00000438237.6	OSBPL10 Links Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein like 10
chr8_-_130016414 Show fit	14.04	ENST00000401979.6 ENST00000517654.5 ENST00000522361.1 ENST00000518167.5	CYRIB Links Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr3_-_196942377 Show fit	13.60	ENST00000447325.5	NCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear cap binding protein subunit 2
chr7_+_128739395 Show fit	13.48	ENST00000479257.5	CALU Links Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr1_+_151156659 Show fit	13.28	ENST00000602841.5	SCNM1 Links Ensembl NCBI GeneCards UniProt Show fit	sodium channel modifier 1
chr19_+_19385815 Show fit	13.18	ENST00000494516.6 ENST00000360315.7	GATAD2A Links Ensembl NCBI GeneCards UniProt Show fit	GATA zinc finger domain containing 2A
chr2_+_65228122 Show fit	13.05	ENST00000542850.2	ACTR2 Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2
chr14_-_69398276 Show fit	12.98	ENST00000557016.6 ENST00000555373.1	ERH Links Ensembl NCBI GeneCards UniProt Show fit	ERH mRNA splicing and mitosis factor
chr11_+_63986821 Show fit	12.87	ENST00000543988.1	OTUB1 Links Ensembl NCBI GeneCards UniProt Show fit	OTU deubiquitinase, ubiquitin aldehyde binding 1
chr2_+_63588953 Show fit	12.77	ENST00000409908.5 ENST00000442225.5 ENST00000233114.13 ENST00000539945.7 ENST00000409476.5 ENST00000436321.5	MDH1 Links Ensembl NCBI GeneCards UniProt Show fit	malate dehydrogenase 1
chr5_+_31532277 Show fit	12.73	ENST00000507818.6 ENST00000325366.14	C5orf22 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 5 open reading frame 22
chr17_+_67717902 Show fit	12.66	ENST00000581106.5 ENST00000253247.9	NOL11 Links Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein 11
chrX_+_47585212 Show fit	12.59	ENST00000445623.1	TIMP1 Links Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 1
chr1_+_42658335 Show fit	12.19	ENST00000677900.1 ENST00000372550.6 ENST00000676675.1 ENST00000304979.8 ENST00000678803.1 ENST00000678333.1 ENST00000440068.6	PPIH Links Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase H
chr11_-_72112068 Show fit	12.06	ENST00000537644.5 ENST00000538919.5 ENST00000539395.1 ENST00000542531.5	ANAPC15 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr7_+_128739292 Show fit	12.04	ENST00000535011.6 ENST00000542996.6 ENST00000249364.9 ENST00000449187.6	CALU Links Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr19_+_58387260 Show fit	11.94	ENST00000598098.5 ENST00000598495.5 ENST00000196551.8 ENST00000596046.1	RPS5 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S5
chr1_-_19485468 Show fit	11.90	ENST00000375142.5	CAPZB Links Ensembl NCBI GeneCards UniProt Show fit	capping actin protein of muscle Z-line subunit beta
chr3_-_196942427 Show fit	11.74	ENST00000411704.1 ENST00000452404.6	NCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear cap binding protein subunit 2
chr19_+_7637099 Show fit	11.60	ENST00000595950.5 ENST00000221283.10 ENST00000441779.6 ENST00000414284.6	STXBP2 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 2
chr8_-_130016395 Show fit	11.13	ENST00000523509.5	CYRIB Links Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr8_-_130016622 Show fit	11.05	ENST00000518283.5 ENST00000519110.5	CYRIB Links Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr14_-_24232332 Show fit	11.03	ENST00000534348.5 ENST00000524927.1 ENST00000250495.10	NEDD8-MDP1 Links Ensembl NCBI GeneCards UniProt Show fit NEDD8 Links Ensembl NCBI GeneCards UniProt Show fit	NEDD8-MDP1 readthrough NEDD8 ubiquitin like modifier
chr1_+_235328959 Show fit	10.71	ENST00000643758.1 ENST00000497327.1	TBCE Links Ensembl NCBI GeneCards UniProt Show fit GGPS1 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin folding cofactor E geranylgeranyl diphosphate synthase 1
chr3_+_33798557 Show fit	10.70	ENST00000457054.6 ENST00000413073.1 ENST00000307296.8	PDCD6IP Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 6 interacting protein
chr2_-_128027273 Show fit	10.68	ENST00000259235.7 ENST00000357702.9 ENST00000424298.5	SAP130 Links Ensembl NCBI GeneCards UniProt Show fit	Sin3A associated protein 130
chr17_+_40287861 Show fit	10.65	ENST00000209728.9 ENST00000580824.5 ENST00000577249.1 ENST00000649662.1	CDC6 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 6
chr20_+_62387086 Show fit	10.64	ENST00000343986.9	RPS21 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S21
chr10_+_73744346 Show fit	10.63	ENST00000345254.9 ENST00000339365.2	SEC24C Links Ensembl NCBI GeneCards UniProt Show fit	SEC24 homolog C, COPII coat complex component
chr7_+_44200960 Show fit	10.52	ENST00000496112.5 ENST00000678359.1 ENST00000223369.3 ENST00000677090.1	YKT6 Links Ensembl NCBI GeneCards UniProt Show fit	YKT6 v-SNARE homolog
chr14_+_24232612 Show fit	10.43	ENST00000560139.5 ENST00000559910.5 ENST00000348719.11	GMPR2 Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase 2
chr20_-_35664925 Show fit	10.37	ENST00000430570.5 ENST00000439806.6 ENST00000437340.5 ENST00000435161.1 ENST00000431148.1	CPNE1 Links Ensembl NCBI GeneCards UniProt Show fit RBM12 Links Ensembl NCBI GeneCards UniProt Show fit	copine 1 RNA binding motif protein 12
chr20_+_35542038 Show fit	10.33	ENST00000357394.8 ENST00000348547.7 ENST00000416206.5 ENST00000640748.1 ENST00000411577.5 ENST00000413587.5	ERGIC3 Links Ensembl NCBI GeneCards UniProt Show fit	ERGIC and golgi 3
chr20_-_35664837 Show fit	10.33	ENST00000414711.5 ENST00000416778.5 ENST00000397442.5 ENST00000440240.5 ENST00000412056.5 ENST00000352393.8 ENST00000458038.5 ENST00000397443.7 ENST00000420363.5 ENST00000434795.5 ENST00000437100.5 ENST00000414664.5 ENST00000359646.1 ENST00000424458.5 ENST00000374114.8 ENST00000374104.7	CPNE1 Links Ensembl NCBI GeneCards UniProt Show fit RBM12 Links Ensembl NCBI GeneCards UniProt Show fit	copine 1 RNA binding motif protein 12
chr15_-_65517653 Show fit	9.85	ENST00000559526.5 ENST00000358939.8 ENST00000560665.1 ENST00000300141.11	DPP8 Links Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl peptidase 8
chr14_+_67360313 Show fit	9.59	ENST00000256383.11	EIF2S1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 subunit alpha
chr11_+_57712574 Show fit	9.54	ENST00000278422.9 ENST00000378312.8	TMX2 Links Ensembl NCBI GeneCards UniProt Show fit	thioredoxin related transmembrane protein 2
chr9_-_127937800 Show fit	9.54	ENST00000373110.4 ENST00000314392.13	DPM2 Links Ensembl NCBI GeneCards UniProt Show fit	dolichyl-phosphate mannosyltransferase subunit 2, regulatory
chr1_+_84164962 Show fit	9.53	ENST00000614872.4 ENST00000394839.6	PRKACB Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-activated catalytic subunit beta
chr8_-_77000194 Show fit	9.49	ENST00000522527.5	PEX2 Links Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 2
chr12_+_49741802 Show fit	9.24	ENST00000423828.5 ENST00000550445.5	TMBIM6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr15_-_65517704 Show fit	9.12	ENST00000321147.10	DPP8 Links Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl peptidase 8
chr12_-_56725284 Show fit	8.95	ENST00000550920.6 ENST00000678376.1 ENST00000550952.6 ENST00000454682.6 ENST00000548563.5 ENST00000546862.6	NACA Links Ensembl NCBI GeneCards UniProt Show fit	nascent polypeptide associated complex subunit alpha
chr19_+_40751179 Show fit	8.91	ENST00000243563.8 ENST00000601393.1	SNRPA Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide A
chr12_-_56725256 Show fit	8.89	ENST00000552540.5 ENST00000678047.1 ENST00000393891.8 ENST00000678416.1 ENST00000678066.1	NACA Links Ensembl NCBI GeneCards UniProt Show fit	nascent polypeptide associated complex subunit alpha
chr1_-_169367746 Show fit	8.84	ENST00000367811.8 ENST00000472647.5	NME7 Links Ensembl NCBI GeneCards UniProt Show fit	NME/NM23 family member 7
chr14_+_24232422 Show fit	8.52	ENST00000620807.4 ENST00000355299.8 ENST00000559836.5	GMPR2 Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase 2
chr12_-_49568099 Show fit	8.47	ENST00000553173.5 ENST00000550165.5 ENST00000343810.9 ENST00000546244.5	MCRS1 Links Ensembl NCBI GeneCards UniProt Show fit	microspherule protein 1
chr7_-_6059139 Show fit	8.19	ENST00000446699.1 ENST00000199389.11	EIF2AK1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 alpha kinase 1
chr14_+_88562952 Show fit	8.10	ENST00000302216.12 ENST00000554602.5 ENST00000556945.5 ENST00000556158.5 ENST00000557607.5 ENST00000555799.5 ENST00000251038.10 ENST00000555755.5	ZC3H14 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 14
chr5_-_892533 Show fit	8.09	ENST00000483173.5	BRD9 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 9
chr6_+_43517079 Show fit	8.05	ENST00000372344.6 ENST00000642195.1 ENST00000643799.1 ENST00000304004.7 ENST00000646433.1 ENST00000607635.2 ENST00000643341.1 ENST00000423780.1	POLR1C Links Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase I and III subunit C
chr19_-_12669388 Show fit	8.02	ENST00000597961.1 ENST00000598732.1 ENST00000222190.9 ENST00000596731.7	ENSG00000269590.1 Links Ensembl NCBI GeneCards UniProt Show fit WDR83OS Links Ensembl NCBI GeneCards UniProt Show fit	novel protein WD repeat domain 83 opposite strand
chr7_+_77798832 Show fit	8.02	ENST00000415251.6 ENST00000275575.11	PHTF2 Links Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr11_-_46121397 Show fit	7.98	ENST00000676320.1	PHF21A Links Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 21A
chr8_+_15540223 Show fit	7.80	ENST00000382020.8 ENST00000506802.5 ENST00000503731.6 ENST00000509380.5	TUSC3 Links Ensembl NCBI GeneCards UniProt Show fit	tumor suppressor candidate 3
chr4_-_82373946 Show fit	7.70	ENST00000352301.8 ENST00000509107.1 ENST00000353341.8 ENST00000313899.12	HNRNPD Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein D
chr3_-_196942500 Show fit	7.59	ENST00000321256.10 ENST00000427641.2	NCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear cap binding protein subunit 2
chr17_+_82051865 Show fit	7.54	ENST00000578552.5 ENST00000320548.8 ENST00000624957.3 ENST00000581578.5 ENST00000583885.5 ENST00000583641.5 ENST00000623691.3 ENST00000581418.5 ENST00000306823.10 ENST00000392358.6	GPS1 Links Ensembl NCBI GeneCards UniProt Show fit	G protein pathway suppressor 1
chr7_+_93921720 Show fit	7.52	ENST00000248564.6	GNG11 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit gamma 11
chr17_-_49677976 Show fit	7.49	ENST00000665825.1 ENST00000508805.5 ENST00000515508.6 ENST00000451526.6 ENST00000507970.5	SPOP Links Ensembl NCBI GeneCards UniProt Show fit	speckle type BTB/POZ protein
chr2_+_71068603 Show fit	7.44	ENST00000443938.6	NAGK Links Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine kinase
chr12_-_56725322 Show fit	7.37	ENST00000679092.1	NACA Links Ensembl NCBI GeneCards UniProt Show fit	nascent polypeptide associated complex subunit alpha
chr6_+_159790448 Show fit	7.34	ENST00000367034.5	MRPL18 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L18
chr12_+_50400809 Show fit	7.21	ENST00000293618.12 ENST00000429001.7 ENST00000398473.7 ENST00000548174.5 ENST00000548697.5 ENST00000548993.5 ENST00000614335.4 ENST00000522085.5 ENST00000615080.4 ENST00000518444.5 ENST00000551886.5 ENST00000523389.5 ENST00000518561.5 ENST00000347328.9 ENST00000550260.1	LARP4 Links Ensembl NCBI GeneCards UniProt Show fit	La ribonucleoprotein 4
chr1_+_23791203 Show fit	7.05	ENST00000374503.7 ENST00000374502.7	LYPLA2 Links Ensembl NCBI GeneCards UniProt Show fit	lysophospholipase 2
chr1_+_23791138 Show fit	6.98	ENST00000374514.8 ENST00000420982.5 ENST00000374505.6	LYPLA2 Links Ensembl NCBI GeneCards UniProt Show fit	lysophospholipase 2
chr15_+_43800586 Show fit	6.97	ENST00000442995.4 ENST00000458412.2	HYPK Links Ensembl NCBI GeneCards UniProt Show fit	huntingtin interacting protein K
chr1_-_20661356 Show fit	6.77	ENST00000602624.7 ENST00000464364.1	DDOST Links Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr8_-_77000070 Show fit	6.70	ENST00000357039.9	PEX2 Links Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 2
chr21_-_44801813 Show fit	6.69	ENST00000345496.7	UBE2G2 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 G2
chr7_+_100676112 Show fit	6.67	ENST00000412215.5 ENST00000393924.1	GNB2 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit beta 2
chr6_+_33289650 Show fit	6.66	ENST00000463584.1	PFDN6 Links Ensembl NCBI GeneCards UniProt Show fit	prefoldin subunit 6
chr2_+_71068636 Show fit	6.25	ENST00000244204.11 ENST00000533981.5	NAGK Links Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine kinase
chr7_+_77798750 Show fit	6.24	ENST00000416283.6 ENST00000422959.6 ENST00000307305.12 ENST00000424760.5	PHTF2 Links Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr1_+_84164370 Show fit	6.21	ENST00000446538.5 ENST00000610703.4 ENST00000370682.7 ENST00000394838.6 ENST00000432111.5	PRKACB Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-activated catalytic subunit beta
chr12_-_122716790 Show fit	6.20	ENST00000528880.3	HCAR3 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 3
chr2_+_177212724 Show fit	6.17	ENST00000677043.1 ENST00000677863.1 ENST00000676681.1 ENST00000678111.1 ENST00000676874.1 ENST00000676736.1 ENST00000411529.6 ENST00000435711.5	HNRNPA3 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein A3
chr8_-_56074312 Show fit	5.82	ENST00000523936.5	RPS20 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S20
chr15_-_65517244 Show fit	5.82	ENST00000341861.9	DPP8 Links Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl peptidase 8
chr9_+_36190856 Show fit	5.77	ENST00000433436.6 ENST00000538225.5 ENST00000540080.5	CLTA Links Ensembl NCBI GeneCards UniProt Show fit	clathrin light chain A
chr2_-_128028010 Show fit	5.74	ENST00000643581.2 ENST00000450957.1	SAP130 Links Ensembl NCBI GeneCards UniProt Show fit	Sin3A associated protein 130
chr1_-_20661518 Show fit	5.72	ENST00000415136.6	DDOST Links Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr9_+_36190908 Show fit	5.66	ENST00000345519.10 ENST00000470744.5 ENST00000242285.10 ENST00000466396.5 ENST00000396603.6	CLTA Links Ensembl NCBI GeneCards UniProt Show fit	clathrin light chain A
chr10_+_5684828 Show fit	5.58	ENST00000328090.9 ENST00000496681.5	TASOR2 Links Ensembl NCBI GeneCards UniProt Show fit	transcription activation suppressor family member 2
chr7_+_114922346 Show fit	5.57	ENST00000393486.5	MDFIC Links Ensembl NCBI GeneCards UniProt Show fit	MyoD family inhibitor domain containing
chr6_-_31592952 Show fit	5.57	ENST00000376073.8 ENST00000376072.7	NCR3 Links Ensembl NCBI GeneCards UniProt Show fit	natural cytotoxicity triggering receptor 3
chr11_-_33161461 Show fit	5.54	ENST00000323959.9 ENST00000431742.2 ENST00000524827.6	CSTF3 Links Ensembl NCBI GeneCards UniProt Show fit	cleavage stimulation factor subunit 3
chr22_+_37805218 Show fit	5.50	ENST00000340857.4	H1-0 Links Ensembl NCBI GeneCards UniProt Show fit	H1.0 linker histone
chr2_+_71068278 Show fit	5.47	ENST00000613852.4 ENST00000455662.6 ENST00000531934.5	NAGK Links Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine kinase
chr1_+_161202147 Show fit	5.28	ENST00000392179.5 ENST00000678511.1 ENST00000677453.1 ENST00000678783.1 ENST00000679218.1 ENST00000676972.1	NDUFS2 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S2
chr17_-_49678074 Show fit	5.28	ENST00000505581.5 ENST00000504102.6 ENST00000514121.6 ENST00000393328.6 ENST00000509079.6 ENST00000347630.6	SPOP Links Ensembl NCBI GeneCards UniProt Show fit	speckle type BTB/POZ protein
chr14_-_73950075 Show fit	5.27	ENST00000286544.5	FAM161B Links Ensembl NCBI GeneCards UniProt Show fit	FAM161 centrosomal protein B
chr3_-_100401028 Show fit	5.17	ENST00000284320.6	TOMM70 Links Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 70
chr11_-_112086727 Show fit	5.15	ENST00000504148.3 ENST00000541231.1	TIMM8B Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 8 homolog B
chr3_+_100709290 Show fit	5.05	ENST00000675047.1 ENST00000490574.6 ENST00000675543.1 ENST00000676308.1 ENST00000675499.1	TFG Links Ensembl NCBI GeneCards UniProt Show fit	trafficking from ER to golgi regulator
chr1_-_110963936 Show fit	5.05	ENST00000485275.2	LRIF1 Links Ensembl NCBI GeneCards UniProt Show fit	ligand dependent nuclear receptor interacting factor 1
chr4_-_82891095 Show fit	5.05	ENST00000514326.5 ENST00000505434.5 ENST00000503058.5 ENST00000348405.8 ENST00000505984.5 ENST00000395310.7 ENST00000513858.5 ENST00000508479.5 ENST00000443462.6 ENST00000508502.5 ENST00000509142.5 ENST00000311785.11 ENST00000448323.5	SEC31A Links Ensembl NCBI GeneCards UniProt Show fit	SEC31 homolog A, COPII coat complex component
chr20_-_20052389 Show fit	5.04	ENST00000536226.2	CRNKL1 Links Ensembl NCBI GeneCards UniProt Show fit	crooked neck pre-mRNA splicing factor 1
chr14_-_77616630 Show fit	5.04	ENST00000216484.7	SPTLC2 Links Ensembl NCBI GeneCards UniProt Show fit	serine palmitoyltransferase long chain base subunit 2
chr18_-_57621741 Show fit	5.03	ENST00000587194.1 ENST00000591599.5 ENST00000588661.5 ENST00000256854.10	NARS1 Links Ensembl NCBI GeneCards UniProt Show fit	asparaginyl-tRNA synthetase 1
chr6_-_31592992 Show fit	5.01	ENST00000340027.10	NCR3 Links Ensembl NCBI GeneCards UniProt Show fit	natural cytotoxicity triggering receptor 3
chr8_-_56993803 Show fit	5.01	ENST00000262644.9	BPNT2 Links Ensembl NCBI GeneCards UniProt Show fit	3'(2'), 5'-bisphosphate nucleotidase 2
chr12_-_122703346 Show fit	4.82	ENST00000328880.6	HCAR2 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 2
chr20_-_63568074 Show fit	4.80	ENST00000427522.6	HELZ2 Links Ensembl NCBI GeneCards UniProt Show fit	helicase with zinc finger 2
chr4_+_41990496 Show fit	4.80	ENST00000264451.12	SLC30A9 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 30 member 9
chrX_+_153179276 Show fit	4.75	ENST00000356661.7	MAGEA1 Links Ensembl NCBI GeneCards UniProt Show fit	MAGE family member A1
chrX_+_124346544 Show fit	4.70	ENST00000371139.9	SH2D1A Links Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chr16_-_28491996 Show fit	4.63	ENST00000568497.6 ENST00000357857.14 ENST00000395653.9 ENST00000635973.1 ENST00000568443.2 ENST00000568558.6 ENST00000565688.5 ENST00000637100.1 ENST00000359984.12 ENST00000636147.2 ENST00000567963.6	CLN3 Links Ensembl NCBI GeneCards UniProt Show fit	CLN3 lysosomal/endosomal transmembrane protein, battenin
chr12_+_120534342 Show fit	4.60	ENST00000542438.1 ENST00000325954.9	RNF10 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 10
chr12_+_102120172 Show fit	4.58	ENST00000327680.7 ENST00000541394.5 ENST00000543784.5	PARPBP Links Ensembl NCBI GeneCards UniProt Show fit	PARP1 binding protein
chr14_+_88563088 Show fit	4.52	ENST00000393514.9	ZC3H14 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 14
chr7_-_38909174 Show fit	4.39	ENST00000395969.6 ENST00000310301.9 ENST00000414632.5	VPS41 Links Ensembl NCBI GeneCards UniProt Show fit	VPS41 subunit of HOPS complex
chr1_+_193059587 Show fit	4.36	ENST00000400968.7 ENST00000415442.2 ENST00000506303.1	RO60 Links Ensembl NCBI GeneCards UniProt Show fit	Ro60, Y RNA binding protein
chr6_-_42746054 Show fit	4.33	ENST00000372876.2	TBCC Links Ensembl NCBI GeneCards UniProt Show fit	tubulin folding cofactor C
chr3_-_37176305 Show fit	4.31	ENST00000440230.5 ENST00000421276.6 ENST00000354379.8	LRRFIP2 Links Ensembl NCBI GeneCards UniProt Show fit	LRR binding FLII interacting protein 2
chr12_+_49741565 Show fit	4.02	ENST00000549445.5 ENST00000550951.5 ENST00000549385.5 ENST00000548713.5 ENST00000548201.5	TMBIM6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr6_-_116060859 Show fit	4.01	ENST00000606080.2	FRK Links Ensembl NCBI GeneCards UniProt Show fit	fyn related Src family tyrosine kinase
chrX_+_124346525 Show fit	3.96	ENST00000360027.4	SH2D1A Links Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chr1_-_110963897 Show fit	3.84	ENST00000369763.5	LRIF1 Links Ensembl NCBI GeneCards UniProt Show fit	ligand dependent nuclear receptor interacting factor 1
chr16_-_28491759 Show fit	3.73	ENST00000565316.6 ENST00000355477.10 ENST00000636228.1 ENST00000333496.14 ENST00000565778.6 ENST00000357806.11	CLN3 Links Ensembl NCBI GeneCards UniProt Show fit	CLN3 lysosomal/endosomal transmembrane protein, battenin
chr11_+_63986411 Show fit	3.68	ENST00000538426.6 ENST00000543004.5	OTUB1 Links Ensembl NCBI GeneCards UniProt Show fit	OTU deubiquitinase, ubiquitin aldehyde binding 1
chrX_+_124346571 Show fit	3.64	ENST00000477673.2	SH2D1A Links Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chr18_+_23453275 Show fit	3.48	ENST00000581585.5 ENST00000339486.8 ENST00000577501.5	RIOK3 Links Ensembl NCBI GeneCards UniProt Show fit	RIO kinase 3
chr20_-_35411963 Show fit	3.40	ENST00000349714.9 ENST00000438533.5 ENST00000359226.6 ENST00000374384.6 ENST00000374385.10 ENST00000424405.5 ENST00000397554.5 ENST00000374380.6	UQCC1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquinol-cytochrome c reductase complex assembly factor 1
chr2_+_96266211 Show fit	3.31	ENST00000488633.2	CIAO1 Links Ensembl NCBI GeneCards UniProt Show fit	cytosolic iron-sulfur assembly component 1
chr1_+_193059448 Show fit	3.29	ENST00000432079.5	RO60 Links Ensembl NCBI GeneCards UniProt Show fit	Ro60, Y RNA binding protein
chr12_+_120534697 Show fit	3.28	ENST00000675818.1 ENST00000413266.6	ENSG00000288623.1 Links Ensembl NCBI GeneCards UniProt Show fit RNF10 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein ring finger protein 10
chr11_+_112086853 Show fit	3.17	ENST00000528182.5 ENST00000528048.5 ENST00000375549.8 ENST00000528021.6 ENST00000526592.5 ENST00000525291.5	SDHD Links Ensembl NCBI GeneCards UniProt Show fit	succinate dehydrogenase complex subunit D
chr1_-_42335189 Show fit	3.16	ENST00000361776.5 ENST00000445886.5 ENST00000361346.6	FOXJ3 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box J3
chr1_-_61725121 Show fit	2.89	ENST00000371177.2 ENST00000606498.5	TM2D1 Links Ensembl NCBI GeneCards UniProt Show fit	TM2 domain containing 1
chrX_+_49235460 Show fit	2.87	ENST00000376227.4	CCDC22 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 22
chr1_-_156728388 Show fit	2.72	ENST00000313146.10	ISG20L2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20 like 2
chr12_+_54028433 Show fit	2.68	ENST00000243108.5	HOXC6 Links Ensembl NCBI GeneCards UniProt Show fit	homeobox C6
chr16_+_67199509 Show fit	2.51	ENST00000477898.5	ELMO3 Links Ensembl NCBI GeneCards UniProt Show fit	engulfment and cell motility 3
chr1_-_156728679 Show fit	2.35	ENST00000368219.2	ISG20L2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20 like 2
chr2_+_137964279 Show fit	1.99	ENST00000329366.8	HNMT Links Ensembl NCBI GeneCards UniProt Show fit	histamine N-methyltransferase
chr7_-_92246045 Show fit	1.98	ENST00000394507.5 ENST00000458177.6 ENST00000340022.6 ENST00000444960.5	KRIT1 Links Ensembl NCBI GeneCards UniProt Show fit	KRIT1 ankyrin repeat containing
chr9_-_129028277 Show fit	1.97	ENST00000372554.8 ENST00000372564.8	SH3GLB2 Links Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing GRB2 like, endophilin B2
chr1_+_203795614 Show fit	1.91	ENST00000367210.3 ENST00000432282.5 ENST00000453771.5 ENST00000367214.5 ENST00000639812.1 ENST00000367212.7 ENST00000332127.8 ENST00000550078.2	ZC3H11A Links Ensembl NCBI GeneCards UniProt Show fit ZBED6 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 11A zinc finger BED-type containing 6
chr14_+_22462932 Show fit	1.55	ENST00000390477.2	TRDC Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor delta constant
chr1_-_184754808 Show fit	1.51	ENST00000318130.13 ENST00000367512.7	EDEM3 Links Ensembl NCBI GeneCards UniProt Show fit	ER degradation enhancing alpha-mannosidase like protein 3
chr15_+_43371062 Show fit	1.47	ENST00000260383.11 ENST00000564079.6	TUBGCP4 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin gamma complex associated protein 4
chr14_-_73950393 Show fit	1.45	ENST00000651776.1	FAM161B Links Ensembl NCBI GeneCards UniProt Show fit	FAM161 centrosomal protein B

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.2	30.5	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
8.2	32.9	GO:0006408	snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
7.3	21.8	GO:0090149	mitochondrial membrane fission(GO:0090149)
6.8	27.2	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
6.6	19.9	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
5.2	15.5	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
4.0	27.8	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
3.7	22.4	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
3.6	10.7	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
3.6	21.3	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
3.2	19.2	GO:0006050	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
2.9	17.6	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
2.8	8.5	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
2.8	8.4	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
2.7	8.2	GO:0006447	regulation of translational initiation by iron(GO:0006447)
2.7	10.6	GO:1904116	traversing start control point of mitotic cell cycle(GO:0007089) response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
2.6	15.7	GO:0097338	response to clozapine(GO:0097338)
2.6	7.7	GO:1901355	response to rapamycin(GO:1901355)
2.4	7.3	GO:0035928	rRNA import into mitochondrion(GO:0035928)
2.4	44.0	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
2.4	14.5	GO:0031438	negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
2.4	37.8	GO:0021670	lateral ventricle development(GO:0021670)
2.4	16.6	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
2.3	20.7	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
2.2	6.5	GO:0033386	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
2.1	14.7	GO:0006499	N-terminal protein myristoylation(GO:0006499)
2.1	12.6	GO:0061450	trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163) negative regulation of trophoblast cell migration(GO:1901164)
2.0	22.5	GO:0007144	female meiosis I(GO:0007144)
1.9	9.5	GO:0019348	dolichol metabolic process(GO:0019348)
1.9	17.1	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
1.8	16.0	GO:0009249	protein lipoylation(GO:0009249)
1.8	10.6	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.8	14.0	GO:0002084	protein depalmitoylation(GO:0002084)
1.6	14.6	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
1.4	29.9	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
1.4	16.7	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
1.3	136.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
1.3	26.1	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
1.3	5.0	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
1.3	30.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
1.2	10.6	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) rRNA 3'-end processing(GO:0031125)
1.2	12.8	GO:0006108	malate metabolic process(GO:0006108)
1.2	3.5	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
1.1	14.0	GO:0090168	Golgi reassembly(GO:0090168)
1.1	17.0	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
1.1	3.2	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.0	21.5	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
1.0	44.6	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
1.0	15.7	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
1.0	4.8	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.9	20.9	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.9	17.9	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.9	4.4	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.9	7.8	GO:0015693	magnesium ion transport(GO:0015693)
0.8	11.0	GO:0045116	protein neddylation(GO:0045116)
0.8	7.9	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.8	31.8	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.7	12.7	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.7	49.9	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.7	16.1	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.7	3.4	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.7	19.0	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.7	14.1	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.7	37.4	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.6	4.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.6	12.3	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.6	66.1	GO:0043488	regulation of mRNA stability(GO:0043488)
0.6	19.6	GO:0090383	phagosome acidification(GO:0090383)
0.5	21.8	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.4	15.6	GO:0046039	GTP metabolic process(GO:0046039)
0.4	11.4	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.4	16.2	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.4	1.5	GO:0097466	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.4	21.4	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.3	1.5	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3	14.2	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.3	14.4	GO:0000281	mitotic cytokinesis(GO:0000281)
0.3	7.5	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.3	5.5	GO:0006379	mRNA cleavage(GO:0006379)
0.2	3.3	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2	8.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.2	10.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.2	8.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2	6.4	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.2	2.9	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2	5.6	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.2	3.0	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.2	13.2	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1	4.8	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.1	8.0	GO:0006446	regulation of translational initiation(GO:0006446)
0.1	3.4	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.1	5.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.7	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.1	4.8	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	6.2	GO:0051028	mRNA transport(GO:0051028)
0.0	18.2	GO:0043687	post-translational protein modification(GO:0043687)
0.0	4.0	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	0.7	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	5.1	GO:0007605	sensory perception of sound(GO:0007605)
0.0	1.6	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	3.7	GO:0006909	phagocytosis(GO:0006909)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.7	46.7	GO:0008537	proteasome activator complex(GO:0008537)
8.2	32.9	GO:0005846	nuclear cap binding complex(GO:0005846)
7.8	69.9	GO:0005672	transcription factor TFIIA complex(GO:0005672)
5.0	25.2	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
4.6	55.7	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
4.2	12.7	GO:0034455	t-UTP complex(GO:0034455)
4.1	12.2	GO:0071001	U4/U6 snRNP(GO:0071001)
4.0	72.2	GO:0031597	cytosolic proteasome complex(GO:0031597)
3.8	19.0	GO:1902560	GMP reductase complex(GO:1902560)
3.5	10.5	GO:0097441	basilar dendrite(GO:0097441)
3.3	40.0	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
3.3	33.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
3.2	9.5	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
3.1	43.8	GO:0001673	male germ cell nucleus(GO:0001673)
3.0	20.9	GO:0044530	supraspliceosomal complex(GO:0044530)
2.8	19.9	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
2.7	16.0	GO:0000172	ribonuclease MRP complex(GO:0000172)
2.6	25.5	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
2.4	9.6	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
2.3	27.8	GO:0071203	F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203)
2.3	76.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
2.3	16.1	GO:0005683	U7 snRNP(GO:0005683)
2.3	45.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
1.9	31.8	GO:0031080	nuclear pore outer ring(GO:0031080)
1.8	19.8	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
1.5	15.1	GO:0071439	clathrin complex(GO:0071439)
1.5	43.5	GO:0005680	anaphase-promoting complex(GO:0005680)
1.5	16.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
1.3	13.0	GO:0034709	methylosome(GO:0034709)
1.3	5.0	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.2	10.7	GO:0090543	Flemming body(GO:0090543)
1.2	11.6	GO:0044194	cytolytic granule(GO:0044194)
1.0	5.0	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.9	6.4	GO:0016272	prefoldin complex(GO:0016272)
0.9	29.9	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.8	3.3	GO:0071817	MMXD complex(GO:0071817)
0.8	14.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.7	15.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.7	12.0	GO:0030127	COPII vesicle coat(GO:0030127)
0.7	16.4	GO:0070822	Sin3-type complex(GO:0070822)
0.7	21.2	GO:0030057	desmosome(GO:0030057)
0.6	3.2	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.6	19.6	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.6	23.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.6	42.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.6	3.5	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.6	5.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.5	16.7	GO:1902555	endoribonuclease complex(GO:1902555)
0.5	16.5	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.5	45.7	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.5	8.0	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.5	8.5	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.5	8.9	GO:0005685	U1 snRNP(GO:0005685)
0.5	13.2	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4	28.3	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.3	20.7	GO:0035577	azurophil granule membrane(GO:0035577)
0.3	17.0	GO:0045171	intercellular bridge(GO:0045171)
0.3	1.5	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.3	6.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.3	17.9	GO:0008023	transcription elongation factor complex(GO:0008023)
0.3	5.1	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.2	12.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.2	3.0	GO:0000346	transcription export complex(GO:0000346)
0.2	8.6	GO:1990391	DNA repair complex(GO:1990391)
0.1	7.5	GO:0008180	COP9 signalosome(GO:0008180)
0.1	4.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	1.5	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	3.6	GO:0051233	spindle midzone(GO:0051233)
0.1	18.1	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	12.6	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	22.5	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.1	8.4	GO:0005776	autophagosome(GO:0005776)
0.1	21.2	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.1	11.9	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1	5.3	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	4.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	2.5	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	1.0	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	4.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.6	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	92.3	GO:0070062	extracellular exosome(GO:0070062)
0.0	2.6	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	4.8	GO:0005874	microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.6	81.1	GO:0061133	endopeptidase activator activity(GO:0061133)
6.5	26.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
4.8	19.2	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
4.0	16.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
4.0	40.0	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
3.8	19.0	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
3.5	21.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
3.3	19.9	GO:0016748	succinyltransferase activity(GO:0016748)
3.3	32.9	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
3.2	9.5	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
2.8	16.7	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
2.6	12.8	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
2.5	29.9	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
2.3	11.6	GO:0030348	syntaxin-3 binding(GO:0030348)
2.1	10.7	GO:0031871	proteinase activated receptor binding(GO:0031871)
2.1	14.5	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
2.0	55.7	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.9	17.1	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
1.8	16.6	GO:0019784	NEDD8-specific protease activity(GO:0019784)
1.8	8.9	GO:1990446	snRNA stem-loop binding(GO:0035614) U1 snRNP binding(GO:1990446)
1.7	5.0	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.6	14.7	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
1.6	8.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.6	37.8	GO:0070628	proteasome binding(GO:0070628)
1.4	8.5	GO:0034046	poly(G) binding(GO:0034046)
1.3	16.0	GO:0004526	ribonuclease P activity(GO:0004526)
1.3	6.5	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.3	20.7	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
1.3	14.0	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.1	44.6	GO:0017025	TBP-class protein binding(GO:0017025)
1.0	6.2	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.0	15.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
1.0	24.8	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.9	12.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.9	17.3	GO:0042609	CD4 receptor binding(GO:0042609)
0.8	18.2	GO:0008494	translation activator activity(GO:0008494)
0.8	11.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.8	3.2	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.7	19.8	GO:0008143	poly(A) binding(GO:0008143)
0.7	67.8	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.7	7.3	GO:0008097	5S rRNA binding(GO:0008097)
0.6	42.7	GO:0003743	translation initiation factor activity(GO:0003743)
0.6	13.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.6	14.4	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.6	12.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.6	10.5	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5	26.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.5	8.0	GO:0001054	RNA polymerase I activity(GO:0001054)
0.4	11.9	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4	27.2	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.4	3.5	GO:0089720	caspase binding(GO:0089720)
0.3	17.9	GO:0031491	nucleosome binding(GO:0031491)
0.3	8.8	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.3	7.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.3	73.1	GO:0051015	actin filament binding(GO:0051015)
0.3	5.6	GO:0030957	Tat protein binding(GO:0030957)
0.3	5.2	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.2	4.8	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.2	6.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.2	1.5	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2	33.0	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.2	8.9	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.2	1.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.2	8.0	GO:0004407	histone deacetylase activity(GO:0004407)
0.2	2.9	GO:0097602	cullin family protein binding(GO:0097602)
0.1	1.5	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	19.6	GO:0015405	primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1	5.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.1	4.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	0.7	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	17.6	GO:0047485	protein N-terminus binding(GO:0047485)
0.1	5.3	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	18.1	GO:0044325	ion channel binding(GO:0044325)
0.1	9.6	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.1	8.7	GO:0051087	chaperone binding(GO:0051087)
0.1	3.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	16.8	GO:0030674	protein binding, bridging(GO:0030674)
0.1	4.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	4.8	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	6.6	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	2.9	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	9.6	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	1.6	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	3.7	GO:0017124	SH3 domain binding(GO:0017124)
0.0	8.2	GO:0003924	GTPase activity(GO:0003924)
0.0	6.3	GO:0016791	phosphatase activity(GO:0016791)
0.0	4.4	GO:0008017	microtubule binding(GO:0008017)
0.0	9.3	GO:0004930	G-protein coupled receptor activity(GO:0004930)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	17.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.8	50.1	PID ATR PATHWAY	ATR signaling pathway
0.7	20.7	PID S1P S1P4 PATHWAY	S1P4 pathway
0.5	35.8	PID BMP PATHWAY	BMP receptor signaling
0.5	12.8	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.4	11.4	PID ARF 3PATHWAY	Arf1 pathway
0.4	24.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.4	11.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.4	15.5	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.3	14.4	PID RAS PATHWAY	Regulation of Ras family activation
0.3	15.7	PID IL3 PATHWAY	IL3-mediated signaling events
0.3	23.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.2	12.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	47.1	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.2	13.2	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	5.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	2.2	PID P73PATHWAY	p73 transcription factor network
0.0	0.7	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	2.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	49.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.1	146.7	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
2.1	16.7	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
1.5	65.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
1.3	34.9	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
1.0	17.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.9	31.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.9	62.6	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.9	33.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.9	23.1	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.8	59.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.8	23.7	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.8	19.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.7	19.6	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.6	14.7	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.6	17.0	REACTOME KINESINS	Genes involved in Kinesins
0.6	66.7	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.6	8.0	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.5	11.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.5	69.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.4	10.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.4	19.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.3	12.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	6.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2	12.8	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.2	25.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.2	5.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	14.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	11.0	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	4.1	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction