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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SREBF2

Z-value: 1.22

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Transcription factors associated with SREBF2

Gene Symbol Gene ID Gene Info
SREBF2
ENSG00000198911.12 SREBF2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SREBF2hg38_v1_chr22_+_41833079_418331420.073.1e-01Click!

Activity profile of SREBF2 motif

Sorted Z-values of SREBF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_74493275 11.19 ENST00000541064.5
NPC2
NPC intracellular cholesterol transporter 2
chr14_-_74493322 10.55 ENST00000553490.5
ENST00000557510.5
NPC2
NPC intracellular cholesterol transporter 2
chr14_-_74493291 10.52 ENST00000238633.6
ENST00000555619.6
ENST00000434013.6
NPC2
NPC intracellular cholesterol transporter 2
chr2_-_55923775 8.40 ENST00000438672.5
ENST00000355426.8
ENST00000440439.5
ENST00000429909.5
ENST00000424207.5
ENST00000452337.5
ENST00000439193.5
ENST00000421664.1
EFEMP1
EGF containing fibulin extracellular matrix protein 1
chr17_-_41918944 8.08 ENST00000352035.7
ENST00000590770.5
ENST00000590151.5
ACLY
ATP citrate lyase
chr12_-_91111460 7.45 ENST00000266718.5
LUM
lumican
chr17_-_41918966 6.96 ENST00000537919.5
ENST00000353196.5
ENST00000393896.6
ACLY
ATP citrate lyase
chr10_-_73096974 6.68 ENST00000440381.5
ENST00000263556.3
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr12_-_52949818 6.59 ENST00000546897.5
ENST00000552551.5
KRT8
keratin 8
chr2_+_27212866 6.54 ENST00000419744.1
ATRAID
all-trans retinoic acid induced differentiation factor
chr19_+_11089446 6.33 ENST00000557933.5
ENST00000455727.6
ENST00000535915.5
ENST00000545707.5
ENST00000558518.6
ENST00000558013.5
LDLR
low density lipoprotein receptor
chr17_-_15265230 6.31 ENST00000676161.1
ENST00000646419.2
ENST00000312280.9
ENST00000494511.7
ENST00000580584.3
ENST00000676221.1
PMP22
peripheral myelin protein 22
chr18_-_23586422 6.28 ENST00000269228.10
NPC1
NPC intracellular cholesterol transporter 1
chr5_-_150155828 5.95 ENST00000261799.9
PDGFRB
platelet derived growth factor receptor beta
chr10_-_73096850 5.88 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr5_-_39424966 5.59 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB2
DAB adaptor protein 2
chr6_+_151239951 4.92 ENST00000402676.7
AKAP12
A-kinase anchoring protein 12
chr19_-_11197516 4.91 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KANK2
KN motif and ankyrin repeat domains 2
chr17_-_82098187 4.51 ENST00000634990.1
FASN
fatty acid synthase
chr8_+_11802667 4.39 ENST00000443614.6
ENST00000220584.9
ENST00000525900.5
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr8_+_11802611 4.28 ENST00000623368.3
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr6_-_31958431 3.91 ENST00000625905.1
ENST00000454913.5
ENST00000436289.6
NELFE
negative elongation factor complex member E
chr8_+_26577843 3.89 ENST00000311151.9
DPYSL2
dihydropyrimidinase like 2
chr1_+_112619824 3.66 ENST00000263168.4
CAPZA1
capping actin protein of muscle Z-line subunit alpha 1
chr6_-_53348902 3.62 ENST00000370913.5
ENST00000304434.11
ELOVL5
ELOVL fatty acid elongase 5
chr10_-_3785197 3.48 ENST00000497571.6
KLF6
Kruppel like factor 6
chr6_-_52995170 3.46 ENST00000370959.1
ENST00000370963.9
GSTA4
glutathione S-transferase alpha 4
chr3_+_50269140 3.17 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
SEMA3B
semaphorin 3B
chr17_+_75261864 3.17 ENST00000245539.11
ENST00000579002.5
MRPS7
mitochondrial ribosomal protein S7
chr5_-_43313403 2.90 ENST00000325110.11
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr5_-_43313473 2.82 ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr1_-_155262348 2.75 ENST00000302631.8
ENST00000355379.3
SCAMP3
secretory carrier membrane protein 3
chr9_+_128689948 2.57 ENST00000372688.8
ENST00000372686.5
SET
SET nuclear proto-oncogene
chr4_+_74365136 2.37 ENST00000244869.3
EREG
epiregulin
chr8_+_123416735 2.27 ENST00000524254.5
NTAQ1
N-terminal glutamine amidase 1
chr9_+_128689201 2.17 ENST00000322030.13
SET
SET nuclear proto-oncogene
chr17_+_75261661 2.08 ENST00000579761.5
MRPS7
mitochondrial ribosomal protein S7
chr8_+_123416766 2.04 ENST00000287387.7
ENST00000650311.1
ENST00000523356.1
NTAQ1
N-terminal glutamine amidase 1
chr11_+_2902258 1.88 ENST00000649076.2
ENST00000449793.6
SLC22A18
solute carrier family 22 member 18
chr6_-_32184243 1.82 ENST00000375055.6
ENST00000375076.9
AGER
advanced glycosylation end-product specific receptor
chr8_+_123416718 1.81 ENST00000523984.5
NTAQ1
N-terminal glutamine amidase 1
chr10_-_3785225 1.73 ENST00000542957.1
KLF6
Kruppel like factor 6
chr6_-_32184287 1.69 ENST00000375069.7
ENST00000375070.7
ENST00000438221.6
ENST00000620802.4
ENST00000538695.2
AGER
advanced glycosylation end-product specific receptor
chr15_+_67067780 1.53 ENST00000679624.1
SMAD3
SMAD family member 3
chr3_+_160399630 1.52 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
SMC4
structural maintenance of chromosomes 4
chr11_+_2902388 1.32 ENST00000380574.5
SLC22A18
solute carrier family 22 member 18
chr8_-_123416327 1.14 ENST00000521903.5
ATAD2
ATPase family AAA domain containing 2
chr1_-_41918666 0.99 ENST00000372584.5
HIVEP3
HIVEP zinc finger 3
chr6_-_32184227 0.91 ENST00000450110.5
ENST00000375067.7
ENST00000375056.6
AGER
advanced glycosylation end-product specific receptor
chr2_+_231707650 0.90 ENST00000409321.5
PTMA
prothymosin alpha
chr6_+_12012304 0.87 ENST00000379388.7
ENST00000627968.2
ENST00000541134.5
HIVEP1
HIVEP zinc finger 1
chr10_-_114684612 0.84 ENST00000533213.6
ENST00000369252.8
ABLIM1
actin binding LIM protein 1
chr10_-_114684457 0.82 ENST00000392955.7
ABLIM1
actin binding LIM protein 1
chr1_+_32013848 0.70 ENST00000327300.12
ENST00000492989.1
KHDRBS1
KH RNA binding domain containing, signal transduction associated 1
chr12_-_48004496 0.70 ENST00000337299.7
COL2A1
collagen type II alpha 1 chain
chr8_-_17722217 0.69 ENST00000381861.7
MTUS1
microtubule associated scaffold protein 1
chr15_+_32717994 0.67 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
GREM1
gremlin 1, DAN family BMP antagonist
chr15_-_82952683 0.62 ENST00000450735.7
ENST00000304231.12
HOMER2
homer scaffold protein 2
chr17_+_81103998 0.61 ENST00000572498.1
BAIAP2
BAR/IMD domain containing adaptor protein 2
chr12_-_48004467 0.60 ENST00000380518.8
COL2A1
collagen type II alpha 1 chain
chr12_-_57846686 0.59 ENST00000548823.1
ENST00000398073.7
CTDSP2
CTD small phosphatase 2
chr19_-_55279690 0.45 ENST00000587959.1
ENST00000585927.1
ENST00000587922.5
ENST00000585698.1
HSPBP1
HSPA (Hsp70) binding protein 1
chr19_-_14112641 0.42 ENST00000536649.5
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
chr11_+_22666604 0.38 ENST00000454584.6
GAS2
growth arrest specific 2
chr13_+_24270681 0.22 ENST00000343003.10
ENST00000399949.6
SPATA13
spermatogenesis associated 13
chr22_+_41833079 0.19 ENST00000612482.4
ENST00000361204.9
SREBF2
sterol regulatory element binding transcription factor 2
chr22_+_23772839 0.18 ENST00000215743.8
MMP11
matrix metallopeptidase 11
chr10_-_50623897 0.09 ENST00000361781.7
ENST00000429490.5
ENST00000619438.4
SGMS1
sphingomyelin synthase 1
chr3_-_171810432 0.06 ENST00000356327.9
ENST00000351298.9
PLD1
phospholipase D1
chr1_+_206470463 0.04 ENST00000581977.7
ENST00000578328.6
ENST00000584998.5
ENST00000579827.6
IKBKE
inhibitor of nuclear factor kappa B kinase subunit epsilon
chr15_-_72783685 0.02 ENST00000456471.3
ENST00000311669.12
ADPGK
ADP dependent glucokinase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 32.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
2.1 6.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
2.0 5.9 GO:2000591 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
1.9 5.6 GO:0035026 leading edge cell differentiation(GO:0035026)
1.6 4.9 GO:1901420 negative regulation of response to alcohol(GO:1901420)
1.5 4.4 GO:1904596 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
1.4 8.7 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
1.4 12.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.2 8.4 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.8 15.0 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.7 7.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.6 6.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.5 6.6 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.5 3.2 GO:0046618 drug export(GO:0046618)
0.5 3.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4 4.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.4 5.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.4 4.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.4 8.7 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.3 2.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 6.3 GO:0032060 bleb assembly(GO:0032060)
0.3 1.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 3.9 GO:1900364 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 5.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.7 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.2 4.7 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.1 3.5 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 3.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.6 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 1.3 GO:0060174 limb bud formation(GO:0060174)
0.1 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 3.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.6 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 3.9 GO:0030516 regulation of axon extension(GO:0030516)
0.0 5.0 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.4 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.8 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 1.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.9 5.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.7 8.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6 6.3 GO:0097443 sorting endosome(GO:0097443)
0.6 3.9 GO:0032021 NELF complex(GO:0032021)
0.4 4.5 GO:0042587 glycogen granule(GO:0042587)
0.4 47.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.3 3.7 GO:0071203 F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203)
0.2 6.3 GO:0043218 compact myelin(GO:0043218)
0.2 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.2 6.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 1.5 GO:0000796 condensin complex(GO:0000796)
0.2 5.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 9.4 GO:0001650 fibrillar center(GO:0001650)
0.0 4.7 GO:0005811 lipid particle(GO:0005811)
0.0 6.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 5.9 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 3.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 6.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 6.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 20.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
2.5 12.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
2.1 8.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
2.0 5.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.5 4.5 GO:0004320 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
1.5 4.4 GO:1904599 advanced glycation end-product binding(GO:1904599)
1.4 8.7 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
1.3 3.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.8 3.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.8 6.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.6 38.5 GO:0015485 cholesterol binding(GO:0015485)
0.5 3.6 GO:0004312 fatty acid synthase activity(GO:0004312) fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 4.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 1.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 5.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 3.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 4.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 7.2 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.7 GO:0016015 morphogen activity(GO:0016015)
0.1 7.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 3.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 5.2 GO:0019843 rRNA binding(GO:0019843)
0.1 0.2 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 4.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 6.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 5.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 4.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 6.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 6.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 12.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 4.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 8.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 1.5 PID AURORA B PATHWAY Aurora B signaling
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 23.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.5 7.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 14.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 8.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 6.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 5.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 3.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 3.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 6.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.3 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins