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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SRY

Z-value: 7.02

Motif logo

Transcription factors associated with SRY

Gene Symbol Gene ID Gene Info
ENSG00000184895.8 SRY

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRYhg38_v1_chrY_-_2787676_27876870.351.0e-07Click!

Activity profile of SRY motif

Sorted Z-values of SRY motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SRY

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_39467672 43.94 ENST00000436143.6
ENST00000441980.6
ENST00000682069.1
ENST00000311042.10
myelin associated oligodendrocyte basic protein
chr3_+_39467598 40.44 ENST00000428261.5
ENST00000420739.5
ENST00000415443.5
ENST00000447324.5
ENST00000383754.7
myelin associated oligodendrocyte basic protein
chr14_-_59630582 20.46 ENST00000395090.5
reticulon 1
chr10_+_11164961 20.15 ENST00000399850.7
ENST00000417956.6
CUGBP Elav-like family member 2
chr17_-_64390852 17.95 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr9_+_136980211 17.83 ENST00000444903.2
prostaglandin D2 synthase
chr10_+_69088096 14.68 ENST00000242465.4
serglycin
chr6_-_32589833 13.25 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr5_-_147056010 12.82 ENST00000394414.5
protein phosphatase 2 regulatory subunit Bbeta
chr1_-_156248084 12.58 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
progestin and adipoQ receptor family member 6
chr6_-_152168291 12.52 ENST00000354674.5
spectrin repeat containing nuclear envelope protein 1
chr5_-_147055968 12.46 ENST00000336640.10
protein phosphatase 2 regulatory subunit Bbeta
chr6_-_152168349 12.36 ENST00000539504.5
spectrin repeat containing nuclear envelope protein 1
chr1_-_156248013 12.28 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr18_-_55589795 12.25 ENST00000568740.5
ENST00000629387.2
transcription factor 4
chr1_-_156248038 12.07 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr11_-_134412234 11.89 ENST00000312527.9
beta-1,3-glucuronyltransferase 1
chr18_-_55635948 11.28 ENST00000565124.4
ENST00000398339.5
transcription factor 4
chr18_-_55589836 11.28 ENST00000537578.5
ENST00000564403.6
transcription factor 4
chr18_-_55321986 11.28 ENST00000570287.6
transcription factor 4
chr18_-_55589770 11.14 ENST00000565018.6
ENST00000636400.2
transcription factor 4
chr5_-_147081428 11.12 ENST00000394413.7
protein phosphatase 2 regulatory subunit Bbeta
chr10_+_11165475 11.06 ENST00000609692.5
ENST00000354897.3
CUGBP Elav-like family member 2
chr2_-_71227055 10.86 ENST00000244221.9
poly(A) binding protein interacting protein 2B
chr3_+_189789672 10.57 ENST00000434928.5
tumor protein p63
chr11_+_114060204 10.56 ENST00000683318.1
zinc finger and BTB domain containing 16
chr10_+_110207587 10.37 ENST00000332674.9
ENST00000453116.5
MAX interactor 1, dimerization protein
chr21_-_31558977 10.36 ENST00000286827.7
ENST00000541036.5
TIAM Rac1 associated GEF 1
chr3_+_115623502 10.20 ENST00000305124.11
ENST00000393780.3
growth associated protein 43
chr5_-_131796921 9.77 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr11_+_131911396 9.56 ENST00000425719.6
ENST00000374784.5
neurotrimin
chr22_+_19723525 9.49 ENST00000366425.4
glycoprotein Ib platelet subunit beta
chr17_-_17972374 9.35 ENST00000318094.14
ENST00000540946.5
ENST00000379504.8
ENST00000542206.5
ENST00000395739.8
ENST00000581396.5
ENST00000535933.5
ENST00000579586.1
target of myb1 like 2 membrane trafficking protein
chr16_-_1782526 9.19 ENST00000566339.6
splA/ryanodine receptor domain and SOCS box containing 3
chr19_-_45768627 9.08 ENST00000560160.1
SIX homeobox 5
chr17_+_17972813 8.93 ENST00000582416.5
ENST00000313838.12
ENST00000399187.6
ENST00000581264.5
ENST00000479684.2
ENST00000584166.5
ENST00000585108.5
ENST00000399182.5
ENST00000579977.1
dynein regulatory complex subunit 3
chr5_-_11589019 8.77 ENST00000511377.5
catenin delta 2
chr16_+_6019585 8.59 ENST00000547372.5
RNA binding fox-1 homolog 1
chr5_-_131797030 8.52 ENST00000615660.4
folliculin interacting protein 1
chr11_+_112961247 8.38 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
neural cell adhesion molecule 1
chr18_-_55322215 8.30 ENST00000457482.7
transcription factor 4
chr10_+_110225955 8.29 ENST00000239007.11
MAX interactor 1, dimerization protein
chr2_-_2331336 7.96 ENST00000648933.1
ENST00000644820.1
myelin transcription factor 1 like
chr5_-_147081462 7.84 ENST00000508267.5
ENST00000504198.5
protein phosphatase 2 regulatory subunit Bbeta
chr17_-_39607876 7.83 ENST00000302584.5
neuronal differentiation 2
chrX_+_108045050 7.55 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr1_+_50105666 7.54 ENST00000651347.1
ELAV like RNA binding protein 4
chr2_-_156342348 7.49 ENST00000409572.5
nuclear receptor subfamily 4 group A member 2
chr18_-_55321640 7.27 ENST00000637169.2
transcription factor 4
chrX_-_107716401 7.16 ENST00000486554.1
ENST00000372390.8
TSC22 domain family member 3
chr1_+_84164370 7.01 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
protein kinase cAMP-activated catalytic subunit beta
chrX_+_108044967 6.96 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr4_+_164754116 6.96 ENST00000507311.1
small integral membrane protein 31
chr11_+_128694052 6.91 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor
chr18_-_55302613 6.88 ENST00000561831.7
transcription factor 4
chr1_+_50106265 6.82 ENST00000357083.8
ELAV like RNA binding protein 4
chr18_+_74534493 6.79 ENST00000358821.8
carnosine dipeptidase 1
chr14_+_36657560 6.77 ENST00000402703.6
paired box 9
chr2_-_86337617 6.65 ENST00000538924.7
ENST00000535845.6
receptor accessory protein 1
chr1_+_50108856 6.63 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr10_-_60389833 6.62 ENST00000280772.7
ankyrin 3
chr2_-_2331225 6.61 ENST00000648627.1
ENST00000649663.1
ENST00000650560.1
ENST00000428368.7
ENST00000648316.1
ENST00000648665.1
ENST00000649313.1
ENST00000399161.7
ENST00000647738.2
myelin transcription factor 1 like
chr11_+_126355634 6.53 ENST00000227495.10
ENST00000676545.1
ENST00000678865.1
ENST00000444328.7
ENST00000677503.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr18_+_74534594 6.47 ENST00000582365.1
carnosine dipeptidase 1
chr2_-_207165923 6.26 ENST00000309446.11
Kruppel like factor 7
chr2_-_86337654 6.19 ENST00000165698.9
receptor accessory protein 1
chr21_-_31160904 6.08 ENST00000636887.1
TIAM Rac1 associated GEF 1
chr5_-_131796965 6.01 ENST00000514667.1
ENST00000511848.1
ENST00000510461.6
novel protein
folliculin interacting protein 1
chr8_+_84183262 5.91 ENST00000522455.5
ENST00000521695.5
ENST00000521268.6
RALY RNA binding protein like
chr1_+_84164962 5.90 ENST00000614872.4
ENST00000394839.6
protein kinase cAMP-activated catalytic subunit beta
chr16_+_6019016 5.76 ENST00000550418.6
RNA binding fox-1 homolog 1
chr8_+_84183534 5.75 ENST00000518566.5
RALY RNA binding protein like
chr11_+_128693887 5.67 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr14_+_91114026 5.61 ENST00000521081.5
ENST00000520328.5
ENST00000524232.5
ENST00000522170.5
ENST00000256324.15
ENST00000519950.5
ENST00000523879.5
ENST00000521077.6
ENST00000518665.6
D-glutamate cyclase
chrX_+_85244075 5.53 ENST00000276123.7
zinc finger protein 711
chr16_-_68448491 5.53 ENST00000561749.1
ENST00000219334.10
sphingomyelin phosphodiesterase 3
chr11_+_112961402 5.46 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
neural cell adhesion molecule 1
chr1_-_177164673 5.45 ENST00000424564.2
ENST00000361833.7
astrotactin 1
chr16_+_2537997 5.32 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr16_-_15643024 5.32 ENST00000540441.6
meiosis regulator and mRNA stability factor 1
chr14_+_91114431 5.23 ENST00000428926.6
ENST00000517362.5
D-glutamate cyclase
chr20_-_3781440 5.17 ENST00000379756.3
sperm flagellar 1
chr16_+_6019071 5.17 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr9_-_23826299 5.13 ENST00000380117.5
ELAV like RNA binding protein 2
chr15_-_34318761 5.11 ENST00000290209.9
solute carrier family 12 member 6
chr14_+_91114388 5.10 ENST00000519019.5
ENST00000523816.5
ENST00000517518.5
D-glutamate cyclase
chr11_+_112961480 5.10 ENST00000621850.4
neural cell adhesion molecule 1
chr13_-_40666600 5.04 ENST00000379561.6
forkhead box O1
chr1_-_151146643 5.03 ENST00000613223.1
semaphorin 6C
chr2_-_2326378 5.02 ENST00000647618.1
myelin transcription factor 1 like
chr17_+_79778135 4.91 ENST00000310942.9
ENST00000269399.5
chromobox 2
chr14_+_91114364 4.85 ENST00000518868.5
D-glutamate cyclase
chr10_-_60572599 4.82 ENST00000503366.5
ankyrin 3
chr5_+_140868945 4.78 ENST00000398640.7
protocadherin alpha 11
chr4_-_173530219 4.69 ENST00000359562.4
heart and neural crest derivatives expressed 2
chrX_+_85244032 4.67 ENST00000373165.7
zinc finger protein 711
chr13_-_46142834 4.62 ENST00000674665.1
lymphocyte cytosolic protein 1
chr5_+_141364231 4.62 ENST00000611914.1
protocadherin gamma subfamily A, 5
chr5_-_150086511 4.55 ENST00000675795.1
colony stimulating factor 1 receptor
chr1_+_66332004 4.52 ENST00000371045.9
ENST00000531025.5
ENST00000526197.5
phosphodiesterase 4B
chr15_-_85794902 4.51 ENST00000337975.6
kelch like family member 25
chr14_+_91114667 4.49 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
D-glutamate cyclase
chr5_+_66958870 4.48 ENST00000405643.5
ENST00000407621.1
ENST00000432426.5
microtubule associated serine/threonine kinase family member 4
chr8_-_133297092 4.35 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr1_+_147902789 4.26 ENST00000369235.2
gap junction protein alpha 8
chr1_-_151146611 4.18 ENST00000341697.7
ENST00000368914.8
semaphorin 6C
chr12_+_94148553 4.00 ENST00000258526.9
plexin C1
chr2_-_165203870 3.98 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr7_+_29479712 3.98 ENST00000412711.6
chimerin 2
chr11_-_82997477 3.94 ENST00000534301.5
RAB30, member RAS oncogene family
chr10_+_91162958 3.92 ENST00000614189.4
polycomb group ring finger 5
chr10_-_60141004 3.91 ENST00000355288.6
ankyrin 3
chr7_+_29480077 3.86 ENST00000439711.6
ENST00000421775.6
ENST00000424025.4
ENST00000409041.7
chimerin 2
chr14_-_22819721 3.81 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
solute carrier family 7 member 7
chr12_+_11649666 3.71 ENST00000396373.9
ETS variant transcription factor 6
chr2_-_165204042 3.70 ENST00000283254.12
ENST00000453007.1
sodium voltage-gated channel alpha subunit 3
chr2_+_86720282 3.70 ENST00000283632.5
required for meiotic nuclear division 5 homolog A
chr2_-_144516397 3.66 ENST00000638128.1
zinc finger E-box binding homeobox 2
chr9_-_23826231 3.66 ENST00000397312.7
ELAV like RNA binding protein 2
chr18_-_55351977 3.64 ENST00000643689.1
transcription factor 4
chr2_-_144516154 3.64 ENST00000637304.1
zinc finger E-box binding homeobox 2
chr7_+_80638633 3.58 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chrX_-_111412162 3.57 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
doublecortin
chr8_+_24294044 3.51 ENST00000265769.9
ADAM metallopeptidase domain 28
chr8_-_71547626 3.50 ENST00000647540.1
ENST00000644229.1
EYA transcriptional coactivator and phosphatase 1
chr19_-_45769204 3.32 ENST00000317578.7
SIX homeobox 5
chr7_-_78771265 3.30 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_-_28348805 3.22 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr9_+_2110354 3.21 ENST00000634772.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_124384513 3.15 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
kalirin RhoGEF kinase
chr14_-_89417148 3.13 ENST00000557258.6
forkhead box N3
chr2_-_219178103 3.09 ENST00000409789.5
cyclin Pas1/PHO80 domain containing 1
chr1_+_43389889 3.08 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr1_-_56579555 3.08 ENST00000371250.4
phospholipid phosphatase 3
chr5_-_24644968 3.05 ENST00000264463.8
cadherin 10
chr3_-_62373015 3.02 ENST00000475839.1
FEZ family zinc finger 2
chr1_-_217137748 2.98 ENST00000493603.5
ENST00000366940.6
estrogen related receptor gamma
chr7_+_144070313 2.98 ENST00000641441.1
olfactory receptor family 2 subfamily A member 25
chr10_+_97319250 2.92 ENST00000371021.5
FRAT regulator of WNT signaling pathway 1
chr3_-_33659441 2.91 ENST00000650653.1
ENST00000480013.6
cytoplasmic linker associated protein 2
chr8_-_144462848 2.89 ENST00000530374.6
cysteine and histidine rich 1
chr17_-_58328756 2.87 ENST00000268893.10
ENST00000343736.9
TSPO associated protein 1
chr8_-_71361860 2.85 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr18_+_11851404 2.82 ENST00000526991.3
charged multivesicular body protein 1B
chr14_+_74348440 2.79 ENST00000256362.5
vertebrae development associated
chr16_+_28846674 2.79 ENST00000322610.12
SH2B adaptor protein 1
chr6_-_162727748 2.73 ENST00000366892.5
ENST00000366898.6
ENST00000366897.5
ENST00000366896.5
ENST00000674250.1
parkin RBR E3 ubiquitin protein ligase
chr5_-_147782681 2.71 ENST00000616793.5
ENST00000333010.6
ENST00000265272.9
janus kinase and microtubule interacting protein 2
chr11_+_67240047 2.70 ENST00000530342.2
lysine demethylase 2A
chr12_-_10098977 2.68 ENST00000315330.8
ENST00000457018.6
C-type lectin domain family 1 member A
chr1_+_25338294 2.67 ENST00000374358.5
transmembrane protein 50A
chr5_+_141364153 2.55 ENST00000518069.2
protocadherin gamma subfamily A, 5
chr9_-_127980976 2.52 ENST00000373095.6
family with sequence similarity 102 member A
chr2_-_159616442 2.47 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
bromodomain adjacent to zinc finger domain 2B
chr7_+_80638510 2.47 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr15_+_90872862 2.45 ENST00000618099.4
furin, paired basic amino acid cleaving enzyme
chr13_-_99258366 2.43 ENST00000397470.5
ENST00000397473.7
G protein-coupled receptor 18
chr4_+_118034480 2.43 ENST00000296499.6
N-deacetylase and N-sulfotransferase 3
chr21_-_18403754 2.42 ENST00000284885.8
transmembrane serine protease 15
chr10_+_122374685 2.35 ENST00000368990.7
ENST00000368989.6
ENST00000463663.6
pleckstrin homology domain containing A1
chr14_+_58427385 2.30 ENST00000354386.10
ENST00000619416.4
KIAA0586
chr8_-_81483226 2.29 ENST00000256104.5
fatty acid binding protein 4
chr12_+_55019967 2.27 ENST00000242994.4
neuronal differentiation 4
chr12_+_54280842 2.27 ENST00000678077.1
ENST00000548688.5
heterogeneous nuclear ribonucleoprotein A1
chr17_-_69141878 2.23 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr3_-_33659097 2.23 ENST00000461133.8
ENST00000496954.2
cytoplasmic linker associated protein 2
chr22_+_39901075 2.20 ENST00000344138.9
GRB2 related adaptor protein 2
chr14_+_58427425 2.18 ENST00000619722.5
ENST00000423743.7
KIAA0586
chr11_-_119729158 2.17 ENST00000264025.8
nectin cell adhesion molecule 1
chr10_-_97334698 2.15 ENST00000371019.4
FRAT regulator of WNT signaling pathway 2
chr21_-_17819386 2.14 ENST00000400559.7
ENST00000400558.7
chromosome 21 open reading frame 91
chr11_+_22338333 2.14 ENST00000263160.4
solute carrier family 17 member 6
chr17_+_38705482 2.14 ENST00000620609.4
MLLT6, PHD finger containing
chrX_+_11760087 2.06 ENST00000649271.1
MSL complex subunit 3
chr3_+_178536205 2.06 ENST00000420517.6
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr6_+_31114793 2.06 ENST00000259881.10
psoriasis susceptibility 1 candidate 1
chr12_-_95217373 2.05 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FYVE, RhoGEF and PH domain containing 6
chr2_+_219178266 2.00 ENST00000430297.7
reticulophagy regulator family member 2
chr6_+_162727941 1.91 ENST00000366888.6
parkin coregulated
chr16_-_4273014 1.86 ENST00000204517.11
transcription factor AP-4
chr17_-_42276341 1.85 ENST00000293328.8
signal transducer and activator of transcription 5B
chr9_-_127847117 1.81 ENST00000480266.5
endoglin
chr22_-_31345770 1.78 ENST00000215919.3
POZ/BTB and AT hook containing zinc finger 1
chr9_-_37465402 1.75 ENST00000307750.5
zinc finger and BTB domain containing 5
chr11_-_44950151 1.75 ENST00000533940.5
ENST00000533937.1
tumor protein p53 inducible protein 11
chr12_-_7503841 1.74 ENST00000359156.8
CD163 molecule
chr21_-_17819343 1.71 ENST00000284881.9
chromosome 21 open reading frame 91
chrX_+_11760035 1.63 ENST00000482871.6
ENST00000648013.1
MSL complex subunit 3
chr1_+_35807974 1.53 ENST00000373210.4
argonaute RISC component 4
chr4_+_94995919 1.51 ENST00000509540.6
bone morphogenetic protein receptor type 1B
chr4_+_94974984 1.45 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr4_-_67883987 1.44 ENST00000283916.11
transmembrane serine protease 11D
chr6_+_138773747 1.43 ENST00000617445.5
coiled-coil domain containing 28A
chr22_-_49827512 1.43 ENST00000404760.5
bromodomain containing 1
chr18_+_33578213 1.30 ENST00000681521.1
ENST00000269197.12
ASXL transcriptional regulator 3
chr1_-_193186599 1.28 ENST00000367434.5
beta-1,3-galactosyltransferase 2
chr7_+_143288215 1.26 ENST00000619992.4
ENST00000310447.10
caspase 2
chr11_-_82997394 1.24 ENST00000525117.5
ENST00000532548.5
RAB30, member RAS oncogene family
chr2_+_104853259 1.20 ENST00000598623.1
ENST00000653688.1
ENST00000662784.1
ENST00000666977.1
ENST00000674056.1
novel transcript, sense overlapping POU3F3
POU class 3 homeobox 3
chr7_+_143959927 1.18 ENST00000624504.1
olfactory receptor family 2 subfamily F member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 84.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
4.9 14.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
4.9 24.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
4.5 17.9 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
4.1 16.4 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
3.8 15.4 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.3 13.2 GO:0002399 MHC class II protein complex assembly(GO:0002399)
2.5 7.5 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
2.5 24.9 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
2.2 12.9 GO:0097338 response to clozapine(GO:0097338)
2.1 8.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
2.0 7.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.8 10.6 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
1.7 40.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
1.4 10.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
1.3 5.0 GO:1902617 response to fluoride(GO:1902617)
1.1 10.2 GO:0016198 axon choice point recognition(GO:0016198)
1.1 3.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.9 4.7 GO:0061032 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.9 7.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.9 2.7 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.9 7.2 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.9 5.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.8 17.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.8 2.4 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.7 5.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.7 31.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 6.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.7 14.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.7 6.1 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6 3.7 GO:0007296 vitellogenesis(GO:0007296)
0.6 2.4 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.6 1.8 GO:0001300 chronological cell aging(GO:0001300)
0.6 19.3 GO:0048665 neuron fate specification(GO:0048665)
0.5 12.6 GO:0035855 megakaryocyte development(GO:0035855)
0.5 3.8 GO:1990822 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.5 10.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.5 3.1 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.5 4.6 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.5 5.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.4 3.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.4 5.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.4 3.0 GO:0043696 forebrain anterior/posterior pattern specification(GO:0021797) dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.4 3.0 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.4 1.2 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.4 4.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.4 2.3 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.4 4.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 10.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.4 9.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.3 1.6 GO:0071895 odontoblast differentiation(GO:0071895)
0.3 1.8 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.3 1.5 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 11.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.3 2.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 1.5 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 2.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.3 0.8 GO:0032252 secretory granule localization(GO:0032252)
0.3 3.1 GO:0008354 germ cell migration(GO:0008354) Bergmann glial cell differentiation(GO:0060020)
0.3 71.8 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.3 9.6 GO:0008038 neuron recognition(GO:0008038)
0.2 13.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 4.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 2.2 GO:0070166 enamel mineralization(GO:0070166) protein localization to cell junction(GO:1902414)
0.2 2.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 2.8 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.2 6.8 GO:0060325 face morphogenesis(GO:0060325)
0.2 0.7 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.2 6.5 GO:0097503 sialylation(GO:0097503)
0.2 1.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 3.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 2.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.2 9.4 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.2 5.3 GO:0007143 female meiotic division(GO:0007143)
0.2 10.9 GO:0019228 neuronal action potential(GO:0019228)
0.2 2.8 GO:0032196 transposition(GO:0032196)
0.2 4.7 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.2 0.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 2.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 3.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 8.8 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 4.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 18.9 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 4.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.9 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 3.4 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 1.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 2.9 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 25.1 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.3 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.5 GO:0009597 detection of virus(GO:0009597)
0.0 1.4 GO:0035902 response to immobilization stress(GO:0035902)
0.0 6.2 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 3.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 5.4 GO:0007286 spermatid development(GO:0007286)
0.0 2.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 6.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 19.6 GO:0006397 mRNA processing(GO:0006397)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 2.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 3.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 1.7 GO:0006953 acute-phase response(GO:0006953)
0.0 1.4 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 1.8 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.7 GO:0001764 neuron migration(GO:0001764)
0.0 3.3 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.4 GO:0032584 growth cone membrane(GO:0032584)
1.9 24.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.2 3.7 GO:0034657 GID complex(GO:0034657)
1.0 40.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.8 4.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.7 16.8 GO:0044295 axonal growth cone(GO:0044295)
0.7 13.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 24.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 12.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 5.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.6 15.4 GO:0043194 spectrin-associated cytoskeleton(GO:0014731) axon initial segment(GO:0043194)
0.6 1.8 GO:0072563 endothelial microparticle(GO:0072563)
0.6 14.7 GO:0042588 zymogen granule(GO:0042588)
0.5 5.1 GO:0045180 basal cortex(GO:0045180)
0.5 3.7 GO:0072487 MSL complex(GO:0072487)
0.5 2.7 GO:0071797 LUBAC complex(GO:0071797)
0.5 52.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.4 3.1 GO:1990130 Iml1 complex(GO:1990130)
0.4 10.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 7.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 76.3 GO:0032993 protein-DNA complex(GO:0032993)
0.3 4.9 GO:0035102 PRC1 complex(GO:0035102)
0.3 0.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 3.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 1.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 4.3 GO:0005922 connexon complex(GO:0005922)
0.2 2.8 GO:0000815 ESCRT III complex(GO:0000815)
0.2 20.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 4.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 4.6 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 12.1 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 6.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 27.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 12.9 GO:0043204 perikaryon(GO:0043204)
0.1 6.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 13.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 4.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 10.6 GO:0016605 PML body(GO:0016605)
0.1 4.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 26.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.1 GO:0005811 lipid particle(GO:0005811)
0.0 3.6 GO:0005875 microtubule associated complex(GO:0005875)
0.0 2.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 84.5 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 84.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
6.1 24.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
4.5 17.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
4.3 12.8 GO:0031849 olfactory receptor binding(GO:0031849)
4.0 83.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
3.0 11.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.6 6.5 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
1.5 4.6 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
1.1 9.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
1.0 2.9 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.9 10.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.8 7.6 GO:0043426 MRF binding(GO:0043426)
0.8 24.9 GO:0005521 lamin binding(GO:0005521)
0.8 12.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.8 2.3 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.8 6.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.7 31.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.6 8.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.6 5.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.6 19.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.6 13.3 GO:0016805 dipeptidase activity(GO:0016805)
0.6 21.0 GO:0017091 AU-rich element binding(GO:0017091)
0.6 2.8 GO:0004803 transposase activity(GO:0004803)
0.5 10.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.5 3.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.5 40.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 13.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.4 2.4 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.4 5.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 46.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.3 3.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.3 5.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.3 4.7 GO:0003680 AT DNA binding(GO:0003680)
0.3 4.3 GO:0005243 gap junction channel activity(GO:0005243)
0.3 5.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 2.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 15.4 GO:0030507 spectrin binding(GO:0030507)
0.2 3.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 8.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 4.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 7.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 1.8 GO:0005534 galactose binding(GO:0005534)
0.2 5.1 GO:0002162 dystroglycan binding(GO:0002162)
0.2 2.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 1.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 0.9 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 7.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 2.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 2.2 GO:0046790 virion binding(GO:0046790)
0.2 1.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.7 GO:0034648 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 8.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 5.9 GO:0070888 E-box binding(GO:0070888)
0.1 1.5 GO:0035198 miRNA binding(GO:0035198)
0.1 8.6 GO:0035064 methylated histone binding(GO:0035064)
0.1 14.2 GO:0001618 virus receptor activity(GO:0001618)
0.1 9.4 GO:0030276 clathrin binding(GO:0030276)
0.1 8.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 10.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 3.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 4.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 0.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 2.3 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 4.9 GO:0005518 collagen binding(GO:0005518)
0.0 11.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 3.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 4.2 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 6.3 GO:0008017 microtubule binding(GO:0008017)
0.0 2.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 13.4 GO:0004888 transmembrane signaling receptor activity(GO:0004888)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 19.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.5 78.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.4 22.1 PID ATR PATHWAY ATR signaling pathway
0.3 14.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 10.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 17.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 13.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 15.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 19.9 PID FGF PATHWAY FGF signaling pathway
0.1 7.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 15.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 8.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 3.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 3.0 PID BMP PATHWAY BMP receptor signaling
0.1 3.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 5.9 PID P73PATHWAY p73 transcription factor network
0.0 3.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 80.3 REACTOME MYOGENESIS Genes involved in Myogenesis
1.1 17.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.7 9.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.7 13.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4 15.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 15.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 16.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 18.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.3 11.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 4.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 16.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 6.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.2 4.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 4.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 3.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 5.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 3.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 8.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 2.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 8.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 3.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones