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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TAF1

Z-value: 9.79

Motif logo

Transcription factors associated with TAF1

Gene Symbol Gene ID Gene Info
ENSG00000147133.17 TAF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TAF1hg38_v1_chrX_+_71366290_71366368-0.534.9e-17Click!

Activity profile of TAF1 motif

Sorted Z-values of TAF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TAF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr13_-_37105664 181.05 ENST00000379800.4
casein kinase 1 alpha 1 like
chr2_+_113890039 149.09 ENST00000443297.5
ENST00000263238.7
ENST00000415792.5
actin related protein 3
chr1_-_155934398 102.61 ENST00000368320.7
ENST00000368321.8
KH domain containing 4, pre-mRNA splicing factor
chr19_-_12933680 96.87 ENST00000593021.1
ENST00000314606.9
ENST00000587981.1
ENST00000423140.6
phenylalanyl-tRNA synthetase subunit alpha
chr8_+_97644164 96.67 ENST00000336273.8
metadherin
chr17_-_64505903 95.95 ENST00000578804.5
DEAD-box helicase 5
chr17_-_64505357 91.62 ENST00000583212.2
ENST00000578190.5
ENST00000579091.5
ENST00000583239.6
DEAD-box helicase 5
chr19_+_797392 89.60 ENST00000627714.2
ENST00000349038.8
ENST00000586481.5
polypyrimidine tract binding protein 1
chr11_-_10858046 89.23 ENST00000413761.7
ENST00000528289.5
ENST00000432999.6
zinc finger BED-type containing 5
chr12_-_82358380 89.06 ENST00000256151.8
ENST00000552377.5
coiled-coil domain containing 59
chr5_-_150904789 88.92 ENST00000427179.5
zinc finger protein 300
chr5_-_150904971 88.67 ENST00000394226.2
ENST00000274599.10
ENST00000418587.6
ENST00000446148.6
zinc finger protein 300
chr5_-_72320217 88.60 ENST00000508863.6
ENST00000522095.1
ENST00000513900.5
ENST00000515404.5
ENST00000261413.10
ENST00000457646.8
mitochondrial ribosomal protein S27
chr21_-_43107553 88.59 ENST00000380276.6
ENST00000291552.9
U2 small nuclear RNA auxiliary factor 1
chr3_-_12664101 86.42 ENST00000251849.9
ENST00000442415.7
Raf-1 proto-oncogene, serine/threonine kinase
chr6_+_36594354 86.28 ENST00000373715.11
serine and arginine rich splicing factor 3
chr19_+_8444967 82.89 ENST00000600092.5
ENST00000325495.9
ENST00000620401.4
ENST00000594907.5
ENST00000596984.5
ENST00000601645.5
heterogeneous nuclear ribonucleoprotein M
chrX_+_48574938 82.51 ENST00000376755.1
RNA binding motif protein 3
chr2_+_27628996 81.66 ENST00000616939.4
ENST00000264718.7
ENST00000610189.2
GPN-loop GTPase 1
chr10_+_74176537 80.45 ENST00000672394.1
adenosine kinase
chrX_+_123961304 80.24 ENST00000371160.5
ENST00000435103.5
stromal antigen 2
chr9_+_128689948 80.20 ENST00000372688.8
ENST00000372686.5
SET nuclear proto-oncogene
chr12_-_48682158 78.37 ENST00000553086.5
ENST00000548304.1
ENST00000550347.5
ENST00000420613.7
ENST00000550931.5
ENST00000550870.1
KAT8 regulatory NSL complex subunit 2
chr5_-_181243880 76.47 ENST00000511566.5
ENST00000511900.5
ENST00000504726.1
ENST00000512968.5
ENST00000626067.1
ENST00000376817.8
ENST00000513027.3
ENST00000512805.6
ENST00000503081.1
receptor for activated C kinase 1
chr14_+_103334803 76.10 ENST00000561325.5
ENST00000392715.6
ENST00000559130.5
ENST00000559532.5
ENST00000558506.1
eukaryotic translation initiation factor 5
chr14_+_77708068 75.94 ENST00000613856.4
SRA stem-loop interacting RNA binding protein
chr3_+_160399630 73.86 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
structural maintenance of chromosomes 4
chr21_-_6499202 72.27 ENST00000619610.2
ENST00000610664.5
ENST00000639996.1
U2 small nuclear RNA auxiliary factor 1 like 5
chr3_+_38165484 71.77 ENST00000446845.5
ENST00000311806.8
oxidative stress responsive kinase 1
chr20_-_50931364 71.54 ENST00000645081.1
ENST00000396029.8
ENST00000396032.8
ENST00000621696.5
ENST00000673732.1
activity dependent neuroprotector homeobox
chr4_-_82429402 71.11 ENST00000602300.5
heterogeneous nuclear ribonucleoprotein D like
chr2_+_241637612 71.03 ENST00000625810.2
ENST00000402096.5
autophagy related 4B cysteine peptidase
chr11_+_4094775 69.87 ENST00000300738.10
ribonucleotide reductase catalytic subunit M1
chr6_-_109382397 69.45 ENST00000512821.5
CD164 molecule
chr17_+_75261864 69.42 ENST00000245539.11
ENST00000579002.5
mitochondrial ribosomal protein S7
chr19_-_2328573 68.38 ENST00000587502.2
ENST00000252622.15
ENST00000585409.2
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chrX_+_71283186 67.04 ENST00000535149.5
non-POU domain containing octamer binding
chr10_+_74176741 66.38 ENST00000673027.1
ENST00000372734.5
ENST00000541550.6
adenosine kinase
chr15_-_88467353 66.14 ENST00000312475.5
ENST00000558531.1
mitochondrial ribosomal protein L46
chr11_+_65919331 65.86 ENST00000376991.6
DR1 associated protein 1
chr6_-_8102481 65.37 ENST00000502429.5
ENST00000429723.6
ENST00000379715.10
ENST00000507463.1
eukaryotic translation elongation factor 1 epsilon 1
chr8_+_124474843 64.36 ENST00000303545.4
ring finger protein 139
chr14_+_22766522 63.99 ENST00000285848.9
ENST00000612549.6
ENST00000431881.6
ENST00000412791.5
ENST00000358043.5
OXA1L mitochondrial inner membrane protein
chr8_+_26291758 62.96 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr11_+_65919480 62.79 ENST00000527119.5
DR1 associated protein 1
chr15_+_40161003 62.42 ENST00000412359.7
ENST00000287598.11
BUB1 mitotic checkpoint serine/threonine kinase B
chr11_+_65919383 62.15 ENST00000312515.7
DR1 associated protein 1
chr19_+_38374758 61.97 ENST00000585598.1
ENST00000602911.5
ENST00000592561.5
proteasome 26S subunit, non-ATPase 8
chr12_-_110742929 61.32 ENST00000340766.9
protein phosphatase 1 catalytic subunit gamma
chr8_-_116755784 61.29 ENST00000518949.5
ENST00000522453.1
ENST00000518995.5
ENST00000521861.6
ENST00000611080.1
eukaryotic translation initiation factor 3 subunit H
chr16_-_28211908 60.90 ENST00000566073.1
ENST00000304658.10
exportin 6
chr19_+_38374549 60.80 ENST00000620216.4
proteasome 26S subunit, non-ATPase 8
chr12_+_95858928 60.58 ENST00000266735.9
ENST00000553192.5
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr16_-_75647655 59.98 ENST00000570215.1
ENST00000319410.9
ENST00000302445.8
lysyl-tRNA synthetase 1
chr5_+_138179093 59.95 ENST00000394894.8
kinesin family member 20A
chr6_-_85642877 59.74 ENST00000369622.8
synaptotagmin binding cytoplasmic RNA interacting protein
chr19_+_55386338 59.65 ENST00000558131.1
ENST00000558752.1
ribosomal protein L28
chr19_+_38374557 59.53 ENST00000215071.9
proteasome 26S subunit, non-ATPase 8
chrX_+_19355582 59.36 ENST00000379804.1
pyruvate dehydrogenase E1 subunit alpha 1
chr11_+_74949241 59.35 ENST00000610881.4
ENST00000530257.5
ENST00000526361.1
ENST00000532972.5
ENST00000263672.11
signal peptidase complex subunit 2
chr1_+_155208727 59.20 ENST00000316721.8
metaxin 1
chr1_-_149927756 58.71 ENST00000271628.9
splicing factor 3b subunit 4
chr14_+_77708076 58.56 ENST00000238688.9
ENST00000557342.6
ENST00000557623.5
ENST00000557431.5
ENST00000556831.5
ENST00000556375.5
ENST00000553981.1
SRA stem-loop interacting RNA binding protein
chr1_+_153634037 58.54 ENST00000368694.8
ENST00000403433.5
chromatin target of PRMT1
chr10_+_28533307 58.23 ENST00000347934.8
WW domain containing adaptor with coiled-coil
chr5_+_171387757 58.11 ENST00000677297.1
ENST00000521672.6
ENST00000679190.1
ENST00000351986.10
ENST00000676589.1
ENST00000679233.1
ENST00000677357.1
ENST00000296930.10
ENST00000393820.2
ENST00000523622.1
nucleophosmin 1
chr6_-_8102046 58.04 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr12_-_122526929 57.65 ENST00000331738.12
ENST00000528279.1
ENST00000344591.8
ENST00000526560.6
arginine and serine rich coiled-coil 2
chr16_-_75647624 57.58 ENST00000568378.5
ENST00000568682.5
lysyl-tRNA synthetase 1
chr2_+_27212320 57.52 ENST00000405489.7
all-trans retinoic acid induced differentiation factor
chr20_-_543718 57.52 ENST00000643600.1
ENST00000645260.1
ENST00000645091.1
ENST00000608066.6
ENST00000400217.7
ENST00000643660.1
ENST00000642689.1
ENST00000646477.1
ENST00000647026.1
ENST00000644710.1
ENST00000644003.1
ENST00000645623.1
ENST00000643680.1
ENST00000644177.1
casein kinase 2 alpha 1
chr17_-_42017345 57.44 ENST00000674411.1
DnaJ heat shock protein family (Hsp40) member C7
chr2_-_38751350 57.28 ENST00000409276.5
ENST00000313117.11
ENST00000446327.6
serine and arginine rich splicing factor 7
chr12_-_110742839 57.05 ENST00000551676.5
ENST00000550991.5
ENST00000335007.10
protein phosphatase 1 catalytic subunit gamma
chr12_+_93467506 56.91 ENST00000549982.6
ENST00000552217.6
ENST00000393128.8
ENST00000547098.5
mitochondrial ribosomal protein L42
chr1_+_46303646 56.82 ENST00000311672.10
ubiquinol-cytochrome c reductase hinge protein
chr12_+_55818033 56.62 ENST00000552672.5
ENST00000243045.10
ENST00000550836.1
ORMDL sphingolipid biosynthesis regulator 2
chr6_+_154733378 56.55 ENST00000367186.7
ENST00000417268.3
ENST00000367178.8
SR-related CTD associated factor 8
chr15_+_41332862 56.06 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr1_+_32651142 55.85 ENST00000414241.7
RB binding protein 4, chromatin remodeling factor
chr16_+_67562453 55.70 ENST00000646076.1
CCCTC-binding factor
chr16_+_67562514 55.66 ENST00000264010.10
ENST00000401394.6
ENST00000646771.1
CCCTC-binding factor
chr20_+_62938111 55.47 ENST00000266069.5
GID complex subunit 8 homolog
chr5_-_134226059 55.22 ENST00000519718.1
ENST00000481195.6
novel protein
protein phosphatase 2 catalytic subunit alpha
chr7_-_23531966 54.91 ENST00000297071.9
transformer 2 alpha homolog
chr1_+_155687946 54.80 ENST00000471642.6
ENST00000471214.5
death associated protein 3
chr3_+_197950509 54.78 ENST00000442341.5
ribosomal protein L35a
chr17_-_42017410 54.69 ENST00000316603.12
ENST00000674175.1
ENST00000674233.1
ENST00000457167.9
ENST00000674306.1
DnaJ heat shock protein family (Hsp40) member C7
chr3_+_197950176 54.61 ENST00000448864.6
ENST00000647248.2
ribosomal protein L35a
chr13_+_37000774 54.58 ENST00000389704.4
exosome component 8
chr8_-_103501890 54.51 ENST00000649416.1
novel protein
chr3_-_123585013 54.49 ENST00000383657.10
3-hydroxyacyl-CoA dehydratase 2
chr11_-_58575846 54.44 ENST00000395074.7
leupaxin
chr17_+_75261661 54.38 ENST00000579761.5
mitochondrial ribosomal protein S7
chr15_-_58933668 54.31 ENST00000380516.7
SAFB like transcription modulator
chr11_-_123059413 54.28 ENST00000524552.5
heat shock protein family A (Hsp70) member 8
chr3_+_184361677 54.21 ENST00000456318.5
ENST00000412877.1
ENST00000438240.5
RNA polymerase II, I and III subunit H
chr7_+_73683588 54.08 ENST00000265758.7
ENST00000441822.5
ENST00000423497.5
BUD23 rRNA methyltransferase and ribosome maturation factor
chrX_+_155216452 53.71 ENST00000286428.7
VHL binding protein 1
chr1_+_153633982 53.67 ENST00000368690.7
ENST00000614256.4
chromatin target of PRMT1
chrX_-_49123721 53.64 ENST00000156109.7
G-patch domain and KOW motifs
chr1_+_62436297 53.61 ENST00000452143.5
ENST00000442679.5
ENST00000371146.5
ubiquitin specific peptidase 1
chr4_-_102825854 53.38 ENST00000350435.11
ubiquitin conjugating enzyme E2 D3
chr1_-_88891496 52.91 ENST00000448623.5
ENST00000370500.10
ENST00000418217.1
general transcription factor IIB
chr8_-_108248700 52.82 ENST00000220849.10
ENST00000678937.1
ENST00000678901.1
ENST00000678243.1
ENST00000677674.1
ENST00000521297.2
ENST00000677272.1
ENST00000522352.6
ENST00000678042.1
ENST00000519627.2
ENST00000521440.6
ENST00000678773.1
ENST00000676698.1
ENST00000518345.2
ENST00000677447.1
ENST00000676548.1
ENST00000519030.6
ENST00000518442.5
eukaryotic translation initiation factor 3 subunit E
chrX_+_24054931 52.42 ENST00000253039.9
ENST00000423068.1
eukaryotic translation initiation factor 2 subunit gamma
chr4_+_56436131 52.21 ENST00000399688.7
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr5_+_53560627 51.72 ENST00000296684.10
ENST00000506765.1
NADH:ubiquinone oxidoreductase subunit S4
chr12_+_68610858 51.67 ENST00000393436.9
ENST00000425247.6
ENST00000250559.14
ENST00000489473.6
ENST00000422358.6
ENST00000541167.5
ENST00000538283.5
ENST00000341355.9
ENST00000537460.5
ENST00000450214.6
ENST00000545270.5
RAP1B, member of RAS oncogene family
chr12_+_69239592 51.67 ENST00000456847.7
ENST00000266679.8
cleavage and polyadenylation specific factor 6
chr20_-_543770 51.57 ENST00000460062.7
ENST00000645187.1
ENST00000647348.1
ENST00000217244.9
ENST00000349736.10
casein kinase 2 alpha 1
chr1_+_93079264 51.10 ENST00000370298.9
ENST00000370303.4
metal response element binding transcription factor 2
chr4_-_102825526 51.06 ENST00000504211.5
ENST00000508476.5
ubiquitin conjugating enzyme E2 D3
chr19_-_8321354 51.04 ENST00000301457.3
NADH:ubiquinone oxidoreductase subunit A7
chr8_-_67062120 50.93 ENST00000357849.9
COP9 signalosome subunit 5
chr11_-_10808913 50.64 ENST00000527419.6
ENST00000530211.6
ENST00000339995.11
ENST00000530702.2
ENST00000524932.6
ENST00000532570.6
eukaryotic translation initiation factor 4 gamma 2
chr3_+_180912656 50.43 ENST00000357559.9
ENST00000491062.5
ENST00000468861.5
ENST00000445140.6
ENST00000484958.5
FMR1 autosomal homolog 1
chr12_+_12813316 50.37 ENST00000352940.8
ENST00000358007.7
ENST00000544400.1
DEAD-box helicase 47
chr11_-_123058991 50.31 ENST00000526686.1
heat shock protein family A (Hsp70) member 8
chr5_+_134874345 50.11 ENST00000358387.9
ENST00000506916.1
thioredoxin domain containing 15
chr15_-_83067199 50.01 ENST00000261721.9
BTB domain containing 1
chr1_+_45583846 49.76 ENST00000437901.6
ENST00000537798.5
ENST00000350030.8
ENST00000527470.5
ENST00000525515.5
ENST00000528238.5
ENST00000470768.5
ENST00000372052.8
ENST00000629893.1
ENST00000351223.7
nuclear autoantigenic sperm protein
chr5_+_66144288 49.69 ENST00000334121.11
splicing regulatory glutamic acid and lysine rich protein 1
chr7_-_23531997 49.48 ENST00000392502.8
ENST00000538367.5
ENST00000621813.4
transformer 2 alpha homolog
chr2_-_149587602 49.21 ENST00000428879.5
ENST00000303319.10
ENST00000422782.2
metabolism of cobalamin associated D
chr10_-_119178791 49.17 ENST00000298510.4
peroxiredoxin 3
chr2_+_241315860 49.14 ENST00000616972.4
septin 2
chr12_+_69585666 49.10 ENST00000543146.2
chaperonin containing TCP1 subunit 2
chrX_-_154019800 48.95 ENST00000444230.5
ENST00000393687.6
ENST00000429936.6
ENST00000369974.6
ENST00000369980.8
interleukin 1 receptor associated kinase 1
chr9_+_128689201 48.92 ENST00000322030.13
SET nuclear proto-oncogene
chr17_-_42017142 48.92 ENST00000589586.6
ENST00000674252.1
ENST00000426588.7
ENST00000589576.6
ENST00000590774.6
ENST00000674166.1
DnaJ heat shock protein family (Hsp40) member C7
chr17_-_4366616 48.83 ENST00000572484.5
ENST00000396981.7
ubiquitin conjugating enzyme E2 G1
chr2_+_264913 48.82 ENST00000439645.6
ENST00000405233.5
ENST00000272065.10
acid phosphatase 1
chr2_+_86199355 48.70 ENST00000254644.12
ENST00000605125.5
ENST00000337109.9
ENST00000409180.1
mitochondrial ribosomal protein L35
chrX_+_155382095 48.57 ENST00000369505.5
coagulation factor VIII associated 2
chrX_-_155458620 48.53 ENST00000622749.2
coagulation factor VIII associated 3
chr1_-_153977260 48.51 ENST00000428469.1
jumping translocation breakpoint
chr5_+_154941063 48.41 ENST00000523037.6
ENST00000265229.12
ENST00000439747.7
ENST00000522038.5
mitochondrial ribosomal protein L22
chr11_+_85628573 48.40 ENST00000393375.5
ENST00000358867.11
ENST00000534341.1
ENST00000531274.1
transmembrane protein 126B
chr7_+_148698857 48.39 ENST00000663835.1
ENST00000655324.1
ENST00000662132.1
ENST00000666124.1
ENST00000325222.9
ENST00000660240.1
cullin 1
chr1_+_32651164 48.21 ENST00000373493.10
ENST00000373485.5
ENST00000458695.6
RB binding protein 4, chromatin remodeling factor
chr20_-_543696 48.21 ENST00000400227.8
ENST00000609525.2
ENST00000646305.1
ENST00000645234.1
ENST00000646814.1
ENST00000644885.1
casein kinase 2 alpha 1
chrX_+_107628428 48.02 ENST00000643795.2
ENST00000372418.4
ENST00000646815.1
ENST00000372435.10
ENST00000372419.3
ENST00000676092.1
phosphoribosyl pyrophosphate synthetase 1
chr5_+_32531786 48.01 ENST00000512913.5
SUB1 regulator of transcription
chr2_+_27211992 47.87 ENST00000380171.8
ENST00000611786.4
all-trans retinoic acid induced differentiation factor
chr7_+_157138912 47.80 ENST00000611269.4
ENST00000348165.10
ubiquitin protein ligase E3C
chr17_-_1400168 47.77 ENST00000573026.1
ENST00000575977.1
ENST00000571732.5
ENST00000264335.13
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
chr1_-_151763334 47.64 ENST00000481777.5
ENST00000368829.3
ENST00000368830.8
mitochondrial ribosomal protein L9
chr4_+_145098269 47.47 ENST00000502586.5
ENST00000296577.9
ATP binding cassette subfamily E member 1
chr5_+_44808930 47.44 ENST00000507110.6
mitochondrial ribosomal protein S30
chr7_+_135557904 46.86 ENST00000285968.11
nucleoporin 205
chr11_-_47426216 46.76 ENST00000530651.5
ENST00000524447.6
ENST00000531051.6
ENST00000526993.1
ENST00000602866.5
proteasome 26S subunit, ATPase 3
chr4_+_17614630 46.72 ENST00000237380.12
mediator complex subunit 28
chr2_+_241315882 46.50 ENST00000401990.5
ENST00000407971.5
ENST00000436795.5
ENST00000411484.5
ENST00000434955.5
ENST00000391971.7
ENST00000402092.6
ENST00000441533.5
ENST00000443492.5
ENST00000437066.5
ENST00000429791.5
septin 2
chr3_+_180912444 46.43 ENST00000305586.11
FMR1 autosomal homolog 1
chr8_+_144095054 46.29 ENST00000318911.5
cytochrome c1
chr14_-_23035223 46.25 ENST00000425762.2
proteasome 20S subunit beta 5
chr2_+_231707650 45.96 ENST00000409321.5
prothymosin alpha
chr22_+_40346508 45.95 ENST00000636714.1
ENST00000216194.11
ENST00000623978.3
ENST00000636265.1
ENST00000680378.1
adenylosuccinate lyase
chr17_+_32350132 45.91 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
zinc finger protein 207
chr21_-_39183398 45.80 ENST00000331573.8
proteasome assembly chaperone 1
chrX_+_154762729 45.77 ENST00000620277.4
dyskerin pseudouridine synthase 1
chr2_-_173964069 45.72 ENST00000652005.2
Sp3 transcription factor
chr4_-_102825767 45.71 ENST00000505207.5
ENST00000502404.5
ENST00000507845.5
ubiquitin conjugating enzyme E2 D3
chr2_+_15591527 45.54 ENST00000434671.2
DEAD-box helicase 1
chr6_-_5260883 45.34 ENST00000330636.9
LYR motif containing 4
chr2_-_173964180 45.07 ENST00000418194.7
Sp3 transcription factor
chr14_-_22929356 45.01 ENST00000397440.8
ENST00000627278.1
ENST00000421938.2
ENST00000324366.13
ENST00000554867.5
ENST00000556616.5
ENST00000216350.12
ENST00000553550.5
ENST00000397441.6
ENST00000553897.5
protein arginine methyltransferase 5
chr6_-_85642922 45.00 ENST00000616122.5
ENST00000678618.1
ENST00000678816.1
ENST00000676630.1
ENST00000678589.1
ENST00000678878.1
ENST00000676542.1
ENST00000355238.11
ENST00000678899.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr11_-_10808304 44.89 ENST00000532082.6
eukaryotic translation initiation factor 4 gamma 2
chrX_-_20266834 44.86 ENST00000379565.9
ribosomal protein S6 kinase A3
chr11_-_119101814 44.82 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr17_+_18858068 44.80 ENST00000536323.5
ENST00000419284.6
ENST00000412418.5
ENST00000575228.5
ENST00000268835.7
ENST00000575102.5
phosphoribosyl pyrophosphate synthetase associated protein 2
chr1_+_27830761 44.64 ENST00000311772.10
ENST00000236412.11
ENST00000373931.8
protein phosphatase 1 regulatory subunit 8
chr15_+_66504959 44.42 ENST00000535141.6
ENST00000613446.4
ENST00000446801.6
zwilch kinetochore protein
chr11_-_47426419 44.28 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
proteasome 26S subunit, ATPase 3
chr1_-_74732997 44.17 ENST00000370872.7
ENST00000370871.7
ENST00000340866.10
ENST00000370870.5
crystallin zeta
chrX_-_53434341 44.14 ENST00000375298.4
ENST00000375304.9
ENST00000684692.1
ENST00000168216.11
hydroxysteroid 17-beta dehydrogenase 10
chr3_+_23810436 44.10 ENST00000467766.5
ENST00000424381.5
ubiquitin conjugating enzyme E2 E1
chr1_-_40097216 44.09 ENST00000641083.1
ENST00000641471.1
ENST00000642050.2
ENST00000433473.8
ENST00000439754.6
ENST00000527311.7
ENST00000641319.1
ENST00000449045.7
palmitoyl-protein thioesterase 1
chr20_-_543811 44.04 ENST00000642160.1
ENST00000646561.1
casein kinase 2 alpha 1
chr13_+_30427950 44.02 ENST00000436446.1
ubiquitin conjugating enzyme E2 L5
chr21_-_39183466 43.95 ENST00000380900.2
proteasome assembly chaperone 1
chr11_-_11353241 43.92 ENST00000528848.3
casein kinase 2 alpha 3
chr10_+_28533706 43.87 ENST00000442148.6
ENST00000448193.5
WW domain containing adaptor with coiled-coil
chr20_+_58981208 43.67 ENST00000602795.6
ENST00000652272.2
negative elongation factor complex member C/D
chr14_+_51240205 43.66 ENST00000457354.7
thioredoxin related transmembrane protein 1
chr20_-_34825612 43.63 ENST00000612493.4
ENST00000616167.1
ENST00000359003.7
nuclear receptor coactivator 6
chr7_+_148698517 43.45 ENST00000665936.1
ENST00000663044.1
ENST00000602748.5
cullin 1
chr17_-_80147118 43.41 ENST00000649764.2
eukaryotic translation initiation factor 4A3
chr6_+_32972187 43.36 ENST00000607833.5
bromodomain containing 2
chr8_-_108443409 43.12 ENST00000678023.1
ENST00000679198.1
ENST00000678881.1
ENST00000677084.1
ENST00000676663.1
ENST00000677614.1
ENST00000677040.1
ENST00000676487.1
ENST00000677409.1
ENST00000678797.1
ENST00000678334.1
eukaryotic translation initiation factor 3 subunit E
chr19_+_797443 43.04 ENST00000356948.11
ENST00000394601.8
ENST00000589575.5
ENST00000587191.3
polypyrimidine tract binding protein 1
chr11_-_14358450 42.99 ENST00000526063.5
ENST00000532814.5
RAS related 2
chr11_-_73976952 42.88 ENST00000545212.1
uncoupling protein 2
chrX_+_154886355 42.88 ENST00000610495.2
coagulation factor VIII associated 1
chrX_-_20266995 42.88 ENST00000644893.1
ENST00000642835.1
ENST00000646610.1
ribosomal protein S6 kinase A3
chr5_+_122775062 42.80 ENST00000379516.7
ENST00000505934.5
ENST00000514949.1
sorting nexin 2
chr1_+_161749762 42.80 ENST00000367943.5
dual specificity phosphatase 12
chr1_-_153977623 42.73 ENST00000356648.5
jumping translocation breakpoint

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
51.3 205.1 GO:0006169 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
49.7 149.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
49.2 49.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
33.6 134.5 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
30.5 91.5 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
28.7 143.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
27.2 81.7 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
26.0 51.9 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
25.7 77.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
25.2 125.8 GO:0006167 AMP biosynthetic process(GO:0006167)
25.1 125.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
24.6 73.8 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
24.2 96.8 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
23.3 116.5 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
22.7 68.1 GO:1902822 lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
22.3 89.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
22.3 111.4 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
21.5 64.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
21.5 64.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
20.6 103.2 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
20.6 144.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
20.4 61.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
19.5 312.8 GO:0043248 proteasome assembly(GO:0043248)
19.4 135.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
19.2 57.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
19.2 38.5 GO:0061198 fungiform papilla formation(GO:0061198)
18.9 56.6 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
18.2 54.7 GO:0006311 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
18.1 18.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
18.1 325.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
18.0 54.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
17.4 69.7 GO:0051697 protein delipidation(GO:0051697)
17.2 68.7 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
17.1 153.8 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
16.9 168.5 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
16.6 116.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
16.0 191.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
15.9 47.8 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
15.9 158.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
15.7 188.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
15.4 138.6 GO:1902416 positive regulation of mRNA binding(GO:1902416)
14.9 14.9 GO:0097695 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
14.9 237.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
14.8 59.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
14.8 44.3 GO:0007174 epidermal growth factor catabolic process(GO:0007174)
14.7 44.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
13.7 13.7 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
13.6 54.5 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
13.5 26.9 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
13.0 39.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
12.8 192.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
12.8 38.3 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
12.7 962.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
12.6 100.4 GO:0033523 histone H2B ubiquitination(GO:0033523)
12.5 50.2 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
12.3 73.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
12.3 36.8 GO:0002192 IRES-dependent translational initiation(GO:0002192)
12.2 122.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
12.2 73.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
11.9 35.7 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
11.9 154.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
11.7 105.6 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
11.7 70.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
11.3 33.8 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
11.3 45.0 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
11.1 88.7 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
11.1 33.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
11.0 33.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
10.7 96.3 GO:0010265 SCF complex assembly(GO:0010265)
10.5 31.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
10.5 52.3 GO:0019348 dolichol metabolic process(GO:0019348)
10.4 62.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
10.3 61.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
10.2 173.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
10.2 30.5 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
10.1 40.4 GO:0043335 protein unfolding(GO:0043335)
10.1 70.4 GO:0080009 mRNA methylation(GO:0080009)
10.0 70.1 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
9.8 59.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
9.7 38.9 GO:0006272 leading strand elongation(GO:0006272)
9.6 38.3 GO:0070269 pyroptosis(GO:0070269)
9.6 19.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
9.6 76.5 GO:0072344 rescue of stalled ribosome(GO:0072344)
9.5 104.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
9.4 112.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
9.1 45.7 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
9.0 45.0 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
8.9 26.8 GO:0036446 peptidyl-serine ADP-ribosylation(GO:0018312) myofibroblast differentiation(GO:0036446) mitochondrial DNA repair(GO:0043504) regulation of myofibroblast differentiation(GO:1904760)
8.9 71.5 GO:0033484 regulation of protein ADP-ribosylation(GO:0010835) nitric oxide homeostasis(GO:0033484)
8.8 70.8 GO:0002084 protein depalmitoylation(GO:0002084)
8.6 138.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
8.6 51.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
8.4 33.8 GO:0042780 tRNA 3'-end processing(GO:0042780)
8.4 42.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
8.2 90.3 GO:1904424 regulation of GTP binding(GO:1904424)
8.2 319.7 GO:0045841 negative regulation of mitotic metaphase/anaphase transition(GO:0045841) mitotic spindle checkpoint(GO:0071174)
8.1 154.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
8.0 32.2 GO:0009838 abscission(GO:0009838)
8.0 23.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
7.6 30.5 GO:0007538 primary sex determination(GO:0007538)
7.6 90.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
7.5 105.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
7.5 30.0 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
7.5 29.9 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
7.5 59.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
7.2 79.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
7.2 86.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
7.2 64.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
7.2 500.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
7.1 42.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
7.0 49.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
6.8 34.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
6.8 61.0 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
6.7 27.0 GO:0051182 coenzyme transport(GO:0051182)
6.7 53.9 GO:1904798 positive regulation of core promoter binding(GO:1904798)
6.7 20.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
6.7 20.0 GO:0046292 formaldehyde metabolic process(GO:0046292)
6.7 26.6 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
6.6 59.5 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
6.5 19.6 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
6.4 96.1 GO:0000338 protein deneddylation(GO:0000338)
6.4 83.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
6.4 31.9 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
6.4 19.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
6.3 31.5 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
6.3 75.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
6.1 42.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
6.0 131.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
5.9 65.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
5.9 58.7 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
5.8 46.7 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
5.8 40.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
5.8 86.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
5.7 229.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
5.6 44.9 GO:0007008 outer mitochondrial membrane organization(GO:0007008)
5.6 61.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
5.6 5.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
5.5 66.5 GO:0046689 response to mercury ion(GO:0046689)
5.5 16.6 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
5.5 16.5 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
5.4 16.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
5.3 74.4 GO:0051661 maintenance of centrosome location(GO:0051661)
5.3 26.5 GO:0051643 endoplasmic reticulum localization(GO:0051643)
5.2 41.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
5.1 30.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
5.1 35.5 GO:0043144 snoRNA processing(GO:0043144)
5.0 110.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
4.9 19.7 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
4.9 24.3 GO:0040031 snRNA modification(GO:0040031)
4.9 14.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
4.9 9.7 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
4.8 38.5 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
4.8 105.4 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
4.8 71.3 GO:0007021 tubulin complex assembly(GO:0007021)
4.7 18.9 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
4.7 149.8 GO:0006337 nucleosome disassembly(GO:0006337)
4.7 37.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
4.7 37.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
4.7 23.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
4.6 106.4 GO:0046931 pore complex assembly(GO:0046931)
4.6 13.9 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
4.6 13.9 GO:0048250 mitochondrial iron ion transport(GO:0048250)
4.6 96.9 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
4.6 9.2 GO:1902415 regulation of mRNA binding(GO:1902415) regulation of RNA binding(GO:1905214)
4.5 35.7 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
4.4 289.1 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
4.4 35.5 GO:0071763 nuclear membrane organization(GO:0071763)
4.4 22.0 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
4.4 8.8 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
4.3 26.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
4.3 17.3 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
4.3 42.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
4.3 59.9 GO:0000920 cell separation after cytokinesis(GO:0000920)
4.3 12.8 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
4.2 34.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
4.2 12.6 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
4.2 29.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
4.2 20.8 GO:0070475 rRNA base methylation(GO:0070475)
4.2 12.5 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
4.1 16.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
4.1 41.0 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
4.1 24.5 GO:0015680 intracellular copper ion transport(GO:0015680)
4.0 20.1 GO:0097240 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
4.0 19.9 GO:1900063 regulation of peroxisome organization(GO:1900063)
3.9 75.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
3.9 39.4 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
3.9 23.6 GO:0052205 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
3.9 7.7 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
3.8 34.6 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
3.8 11.5 GO:0072709 cellular response to sorbitol(GO:0072709)
3.8 34.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
3.8 11.4 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
3.8 15.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
3.8 37.6 GO:0007379 segment specification(GO:0007379)
3.7 22.5 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
3.7 14.8 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
3.7 69.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
3.7 22.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
3.7 21.9 GO:0035617 stress granule disassembly(GO:0035617)
3.6 7.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
3.6 68.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
3.6 46.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
3.6 21.5 GO:0018343 protein farnesylation(GO:0018343)
3.6 49.7 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
3.5 506.7 GO:0045047 protein targeting to ER(GO:0045047)
3.5 242.3 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
3.4 1192.8 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
3.4 24.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
3.4 48.0 GO:0000154 rRNA modification(GO:0000154)
3.4 102.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
3.3 29.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
3.3 39.6 GO:0006449 regulation of translational termination(GO:0006449)
3.3 19.7 GO:0070987 error-free translesion synthesis(GO:0070987)
3.3 9.8 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
3.3 13.0 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
3.2 9.7 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
3.2 12.9 GO:0007386 compartment pattern specification(GO:0007386)
3.2 54.5 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
3.2 15.9 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
3.1 34.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
3.1 49.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
3.1 9.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
3.1 21.4 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
3.0 48.6 GO:0072321 chaperone-mediated protein transport(GO:0072321)
3.0 18.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
3.0 90.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
3.0 27.0 GO:1900086 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
3.0 92.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
3.0 9.0 GO:0048633 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of skeletal muscle tissue growth(GO:0048633)
3.0 35.6 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
3.0 11.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
3.0 50.2 GO:0030488 tRNA methylation(GO:0030488)
2.9 20.6 GO:0048102 autophagic cell death(GO:0048102)
2.8 42.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
2.8 39.2 GO:0043622 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660)
2.8 30.8 GO:0032025 response to cobalt ion(GO:0032025)
2.8 16.6 GO:1990253 cellular response to leucine starvation(GO:1990253)
2.7 211.5 GO:0006413 translational initiation(GO:0006413)
2.7 10.9 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
2.7 171.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
2.7 19.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
2.7 16.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
2.6 42.2 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
2.6 15.6 GO:0042255 ribosome assembly(GO:0042255)
2.6 12.8 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
2.5 12.7 GO:0016240 autophagosome docking(GO:0016240)
2.5 37.5 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
2.4 31.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
2.4 11.9 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
2.4 11.9 GO:0019081 viral translation(GO:0019081)
2.3 190.5 GO:0045454 cell redox homeostasis(GO:0045454)
2.3 23.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
2.3 6.9 GO:0034499 late endosome to Golgi transport(GO:0034499)
2.3 115.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
2.3 53.2 GO:0006491 N-glycan processing(GO:0006491)
2.3 45.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
2.3 9.0 GO:0048496 maintenance of organ identity(GO:0048496)
2.2 87.7 GO:0022904 respiratory electron transport chain(GO:0022904)
2.2 13.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
2.2 28.9 GO:0090110 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
2.2 24.4 GO:0051451 myoblast migration(GO:0051451)
2.2 99.4 GO:0001881 receptor recycling(GO:0001881)
2.2 28.7 GO:0045008 depyrimidination(GO:0045008)
2.2 43.6 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
2.1 53.4 GO:0043555 regulation of translation in response to stress(GO:0043555)
2.1 19.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
2.1 102.0 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
2.0 32.7 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
2.0 10.1 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
2.0 6.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.9 21.4 GO:0015939 pantothenate metabolic process(GO:0015939)
1.9 34.9 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
1.9 17.3 GO:0015886 heme transport(GO:0015886)
1.9 9.4 GO:0035624 receptor transactivation(GO:0035624)
1.9 9.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.9 11.2 GO:0034501 protein localization to kinetochore(GO:0034501)
1.9 24.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
1.8 24.0 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
1.8 14.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.8 27.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.8 3.6 GO:0016584 nucleosome positioning(GO:0016584)
1.8 21.6 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
1.8 8.9 GO:1904753 positive regulation of heart rate by epinephrine(GO:0003065) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
1.8 7.1 GO:0032913 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
1.8 8.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.8 51.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.7 12.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.7 12.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.7 45.8 GO:0043968 histone H2A acetylation(GO:0043968)
1.7 6.7 GO:0051799 negative regulation of hair follicle development(GO:0051799)
1.7 33.6 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
1.6 22.7 GO:0036159 inner dynein arm assembly(GO:0036159)
1.6 16.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
1.6 14.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.6 6.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.6 12.5 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
1.5 39.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
1.5 44.8 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
1.5 35.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
1.5 51.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
1.5 7.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
1.4 7.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
1.4 18.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
1.4 1.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
1.4 15.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
1.4 6.8 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
1.4 17.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
1.4 34.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
1.3 6.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
1.3 158.3 GO:0008380 RNA splicing(GO:0008380)
1.3 11.3 GO:0071421 manganese ion transmembrane transport(GO:0071421)
1.3 41.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
1.3 85.1 GO:0043488 regulation of mRNA stability(GO:0043488)
1.2 59.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
1.2 8.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.1 2.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
1.1 6.8 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
1.1 2.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
1.1 3.3 GO:0097534 post-embryonic camera-type eye development(GO:0031077) lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
1.1 10.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
1.1 3.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.1 10.8 GO:0000212 meiotic spindle organization(GO:0000212)
1.1 26.3 GO:0006414 translational elongation(GO:0006414)
1.0 138.0 GO:0000910 cytokinesis(GO:0000910)
1.0 196.8 GO:0006457 protein folding(GO:0006457)
1.0 12.2 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
1.0 4.0 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
1.0 20.1 GO:0006817 phosphate ion transport(GO:0006817)
1.0 21.1 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
1.0 10.9 GO:0009303 rRNA transcription(GO:0009303)
1.0 7.8 GO:0070459 prolactin secretion(GO:0070459)
1.0 3.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.0 2.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.0 8.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.9 5.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.9 41.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.9 7.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.9 9.6 GO:0045116 protein neddylation(GO:0045116)
0.9 19.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.9 6.0 GO:0060017 parathyroid gland development(GO:0060017)
0.8 7.6 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.8 23.0 GO:0030033 microvillus assembly(GO:0030033)
0.8 6.6 GO:0022615 protein to membrane docking(GO:0022615)
0.8 20.1 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.8 35.1 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.8 11.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.8 10.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.8 17.7 GO:1901998 toxin transport(GO:1901998)
0.8 3.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.7 32.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.7 12.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.7 8.8 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.7 46.9 GO:0007492 endoderm development(GO:0007492)
0.7 42.6 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.7 9.7 GO:0006012 galactose metabolic process(GO:0006012)
0.7 25.6 GO:0017145 stem cell division(GO:0017145)
0.7 4.6 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.6 2.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.6 8.2 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.6 28.7 GO:0045727 positive regulation of translation(GO:0045727)
0.6 8.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.6 28.9 GO:0006611 protein export from nucleus(GO:0006611)
0.6 15.4 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.6 11.7 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.6 2.9 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.6 11.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.6 4.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.6 2.8 GO:0022900 electron transport chain(GO:0022900)
0.6 5.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.5 20.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.5 2.2 GO:0046203 spermidine catabolic process(GO:0046203)
0.5 38.3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.5 6.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.5 15.9 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.5 25.0 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.5 18.7 GO:0051602 response to electrical stimulus(GO:0051602)
0.5 5.5 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.5 3.0 GO:0060356 leucine import(GO:0060356)
0.5 33.4 GO:0001909 leukocyte mediated cytotoxicity(GO:0001909)
0.5 22.9 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.5 15.4 GO:0070207 protein homotrimerization(GO:0070207)
0.5 6.4 GO:0090382 phagosome maturation(GO:0090382)
0.5 3.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.5 6.8 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.5 7.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.5 10.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.5 11.5 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.5 7.3 GO:0044804 nucleophagy(GO:0044804)
0.4 66.5 GO:0008360 regulation of cell shape(GO:0008360)
0.4 9.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 44.8 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.4 5.1 GO:0019985 translesion synthesis(GO:0019985)
0.4 11.0 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.4 19.6 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.4 3.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.4 3.3 GO:0042182 ketone catabolic process(GO:0042182)
0.4 2.2 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.3 19.1 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.3 16.1 GO:0001895 retina homeostasis(GO:0001895)
0.3 3.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.3 20.9 GO:0006968 cellular defense response(GO:0006968)
0.3 7.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 4.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.2 5.1 GO:0006826 iron ion transport(GO:0006826)
0.2 3.4 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.2 17.7 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.2 12.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 1.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 5.1 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228)
0.2 6.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 19.2 GO:0051262 protein tetramerization(GO:0051262)
0.2 1.8 GO:0045475 locomotor rhythm(GO:0045475)
0.2 7.6 GO:0001570 vasculogenesis(GO:0001570)
0.2 34.1 GO:0001649 osteoblast differentiation(GO:0001649)
0.2 35.6 GO:0009165 nucleotide biosynthetic process(GO:0009165)
0.1 1.0 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 3.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 27.9 GO:0051607 defense response to virus(GO:0051607)
0.1 0.9 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 1.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 9.2 GO:0048675 axon extension(GO:0048675)
0.1 1.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.0 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 1.9 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 8.2 GO:0046718 viral entry into host cell(GO:0046718)
0.1 1.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 1.1 GO:0090398 cellular senescence(GO:0090398)
0.1 8.1 GO:0042113 B cell activation(GO:0042113)
0.0 0.9 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.2 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.9 GO:0031016 pancreas development(GO:0031016)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
33.8 304.1 GO:0042382 paraspeckles(GO:0042382)
32.3 96.9 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
28.8 201.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
27.7 138.4 GO:0089701 U2AF(GO:0089701)
27.5 192.7 GO:0016589 NURF complex(GO:0016589)
23.2 92.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
21.9 87.5 GO:0071920 cleavage body(GO:0071920)
20.6 123.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
18.4 128.7 GO:0016272 prefoldin complex(GO:0016272)
18.3 201.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
18.3 91.5 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
18.2 54.5 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
18.1 198.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
17.9 502.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
17.8 89.0 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
17.5 69.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
16.3 48.9 GO:0045323 interleukin-1 receptor complex(GO:0045323)
15.9 207.0 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
15.6 46.8 GO:0030289 protein phosphatase 4 complex(GO:0030289)
15.5 434.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
14.8 44.3 GO:0032419 extrinsic component of lysosome membrane(GO:0032419)
14.7 205.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
14.6 116.5 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
14.3 57.0 GO:0000798 nuclear cohesin complex(GO:0000798)
14.2 42.7 GO:0044611 nuclear pore inner ring(GO:0044611)
14.2 70.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
14.2 56.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
13.7 123.7 GO:0031595 nuclear proteasome complex(GO:0031595)
13.3 120.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
13.1 104.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
13.0 52.0 GO:0044307 dendritic branch(GO:0044307)
12.9 90.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
12.7 50.6 GO:0034457 Mpp10 complex(GO:0034457)
12.1 48.5 GO:1990423 RZZ complex(GO:1990423)
11.4 80.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
11.1 77.5 GO:0044530 supraspliceosomal complex(GO:0044530)
11.0 77.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
11.0 33.0 GO:0035370 UBC13-UEV1A complex(GO:0035370)
10.9 54.7 GO:0032301 MutSalpha complex(GO:0032301) MutSbeta complex(GO:0032302)
10.9 131.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
10.7 42.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
10.4 229.3 GO:0071141 SMAD protein complex(GO:0071141)
10.3 134.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
10.2 40.7 GO:1990246 uniplex complex(GO:1990246)
9.8 78.1 GO:0034709 methylosome(GO:0034709)
9.7 38.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
9.7 203.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
9.7 96.7 GO:0046581 intercellular canaliculus(GO:0046581)
9.6 38.3 GO:0071159 NF-kappaB complex(GO:0071159)
9.4 28.2 GO:0034455 t-UTP complex(GO:0034455)
9.2 73.9 GO:0000796 condensin complex(GO:0000796)
8.7 156.0 GO:0000346 transcription export complex(GO:0000346)
8.6 60.5 GO:0030905 retromer, tubulation complex(GO:0030905)
8.6 34.5 GO:0005873 plus-end kinesin complex(GO:0005873)
8.5 76.5 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
8.4 25.3 GO:0031262 Ndc80 complex(GO:0031262)
8.4 25.2 GO:0071001 U4/U6 snRNP(GO:0071001)
8.3 91.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
8.3 25.0 GO:0034515 proteasome storage granule(GO:0034515)
8.3 174.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
8.3 49.6 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
8.2 24.7 GO:1902737 dendritic filopodium(GO:1902737)
8.2 32.6 GO:0001405 presequence translocase-associated import motor(GO:0001405)
8.0 8.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
8.0 80.1 GO:0070552 BRISC complex(GO:0070552)
8.0 23.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
7.9 39.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
7.8 38.9 GO:0070557 PCNA-p21 complex(GO:0070557)
7.7 23.2 GO:0034657 GID complex(GO:0034657)
7.6 38.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
7.6 53.3 GO:0031415 NatA complex(GO:0031415)
7.5 15.1 GO:0070939 Dsl1p complex(GO:0070939)
7.3 22.0 GO:0035363 histone locus body(GO:0035363)
7.3 73.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
7.3 145.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
7.2 324.6 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
7.2 21.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
7.1 113.2 GO:0042405 nuclear inclusion body(GO:0042405)
7.1 77.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
6.7 53.9 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
6.6 59.3 GO:0005787 signal peptidase complex(GO:0005787)
6.5 64.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
6.4 83.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
6.4 114.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
6.2 359.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
6.1 30.7 GO:0035061 interchromatin granule(GO:0035061)
6.0 24.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
6.0 155.4 GO:0035145 exon-exon junction complex(GO:0035145)
5.8 11.5 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
5.8 69.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
5.8 51.8 GO:0090543 Flemming body(GO:0090543)
5.7 68.3 GO:0008290 F-actin capping protein complex(GO:0008290)
5.7 62.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
5.6 106.5 GO:0000812 Swr1 complex(GO:0000812)
5.5 33.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
5.5 33.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
5.5 105.0 GO:0031616 spindle pole centrosome(GO:0031616)
5.5 16.5 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
5.4 21.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
5.4 64.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
5.3 64.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
5.3 21.3 GO:0030893 meiotic cohesin complex(GO:0030893)
5.2 15.7 GO:1903349 omegasome membrane(GO:1903349)
5.2 31.1 GO:0005816 spindle pole body(GO:0005816)
5.1 61.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
5.1 55.8 GO:0005638 lamin filament(GO:0005638)
5.0 114.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
5.0 39.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
4.9 14.8 GO:0000805 X chromosome(GO:0000805)
4.5 13.6 GO:0044393 microspike(GO:0044393)
4.5 59.0 GO:0008385 IkappaB kinase complex(GO:0008385)
4.4 57.5 GO:0017119 Golgi transport complex(GO:0017119)
4.4 84.0 GO:0030014 CCR4-NOT complex(GO:0030014)
4.3 17.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
4.2 12.7 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
4.2 437.4 GO:0015934 large ribosomal subunit(GO:0015934)
4.2 772.0 GO:0005681 spliceosomal complex(GO:0005681)
4.2 45.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
4.1 45.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
4.1 36.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
4.0 44.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
4.0 28.0 GO:0000788 nuclear nucleosome(GO:0000788)
3.7 47.8 GO:0042555 MCM complex(GO:0042555)
3.6 65.3 GO:0032433 filopodium tip(GO:0032433)
3.6 21.7 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
3.6 28.8 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
3.6 10.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
3.4 30.9 GO:0070765 gamma-secretase complex(GO:0070765)
3.4 44.1 GO:0030677 ribonuclease P complex(GO:0030677)
3.4 50.8 GO:0097346 INO80-type complex(GO:0097346)
3.3 60.0 GO:0001891 phagocytic cup(GO:0001891)
3.3 130.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
3.2 48.1 GO:0010369 chromocenter(GO:0010369)
3.1 102.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
3.1 92.5 GO:0031143 pseudopodium(GO:0031143)
3.0 21.2 GO:0005827 polar microtubule(GO:0005827)
3.0 12.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
2.9 140.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
2.9 52.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
2.9 28.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.8 45.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
2.8 33.1 GO:0030008 TRAPP complex(GO:0030008)
2.7 16.2 GO:0000322 storage vacuole(GO:0000322)
2.7 291.4 GO:0005840 ribosome(GO:0005840)
2.6 58.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
2.6 60.2 GO:0005719 nuclear euchromatin(GO:0005719)
2.6 95.1 GO:0000502 proteasome complex(GO:0000502)
2.4 65.7 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
2.4 48.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
2.4 50.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
2.4 66.5 GO:0002080 acrosomal membrane(GO:0002080)
2.3 16.3 GO:0070187 telosome(GO:0070187)
2.2 17.9 GO:0051286 cell tip(GO:0051286)
2.2 11.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.2 8.8 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
2.2 6.6 GO:0001940 male pronucleus(GO:0001940)
2.2 56.1 GO:0005844 polysome(GO:0005844)
2.1 32.1 GO:0035631 CD40 receptor complex(GO:0035631)
2.1 195.8 GO:0005811 lipid particle(GO:0005811)
2.1 25.1 GO:0030126 COPI vesicle coat(GO:0030126)
2.1 116.2 GO:0005637 nuclear inner membrane(GO:0005637)
2.1 27.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.0 6.0 GO:0018444 translation release factor complex(GO:0018444)
2.0 88.7 GO:0002102 podosome(GO:0002102)
1.9 15.0 GO:0072487 MSL complex(GO:0072487)
1.9 22.4 GO:0042575 DNA polymerase complex(GO:0042575)
1.8 14.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.8 17.9 GO:0030137 COPI-coated vesicle(GO:0030137)
1.8 30.0 GO:0005641 nuclear envelope lumen(GO:0005641)
1.7 8.3 GO:0030896 checkpoint clamp complex(GO:0030896)
1.6 40.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.6 16.1 GO:0097433 dense body(GO:0097433)
1.6 17.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.6 33.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
1.5 66.0 GO:1904115 axon cytoplasm(GO:1904115)
1.5 72.8 GO:0008180 COP9 signalosome(GO:0008180)
1.5 68.9 GO:0005871 kinesin complex(GO:0005871)
1.5 95.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
1.5 110.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
1.5 24.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.4 39.4 GO:0005680 anaphase-promoting complex(GO:0005680)
1.4 14.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.4 22.2 GO:0035102 PRC1 complex(GO:0035102)
1.3 18.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
1.3 5.2 GO:0070761 pre-snoRNP complex(GO:0070761)
1.3 6.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.3 3.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
1.2 40.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
1.2 45.3 GO:0005876 spindle microtubule(GO:0005876)
1.2 3.6 GO:0031010 ISWI-type complex(GO:0031010)
1.2 13.3 GO:0032039 integrator complex(GO:0032039)
1.2 7.1 GO:0005955 calcineurin complex(GO:0005955)
1.2 5.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.1 94.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
1.1 11.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.1 5.3 GO:0005797 Golgi medial cisterna(GO:0005797)
1.1 27.3 GO:0030684 preribosome(GO:0030684)
1.0 34.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.0 138.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.9 44.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.9 85.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.9 58.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.9 158.2 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.9 8.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.9 6.1 GO:0030891 VCB complex(GO:0030891)
0.9 191.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.9 56.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.8 20.2 GO:0000421 autophagosome membrane(GO:0000421)
0.8 29.3 GO:0016592 mediator complex(GO:0016592)
0.8 8.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.8 5.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.8 2.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.8 250.6 GO:0016607 nuclear speck(GO:0016607)
0.7 9.3 GO:0005642 annulate lamellae(GO:0005642)
0.7 61.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.7 12.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.7 11.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.7 22.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.7 33.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6 15.6 GO:0015030 Cajal body(GO:0015030)
0.6 19.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 3.7 GO:0031931 TORC1 complex(GO:0031931)
0.6 10.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.6 45.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.6 144.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.6 64.6 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.6 19.1 GO:0071564 SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.5 7.7 GO:0035861 site of double-strand break(GO:0035861)
0.5 2.5 GO:0030314 junctional membrane complex(GO:0030314)
0.5 7.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 3.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.4 0.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.4 6.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 33.0 GO:0031091 platelet alpha granule(GO:0031091)
0.4 35.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 10.9 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.3 13.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 5.3 GO:0044295 axonal growth cone(GO:0044295)
0.2 13.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 1.4 GO:0061700 GATOR2 complex(GO:0061700)
0.2 10.3 GO:0031526 brush border membrane(GO:0031526)
0.2 52.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 19.5 GO:0005795 Golgi stack(GO:0005795)
0.2 71.3 GO:0005635 nuclear envelope(GO:0005635)
0.2 0.9 GO:0005869 dynactin complex(GO:0005869)
0.1 47.9 GO:0010008 endosome membrane(GO:0010008)
0.1 3.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 18.3 GO:0005769 early endosome(GO:0005769)
0.1 2.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 4.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 169.8 GO:0070062 extracellular exosome(GO:0070062)
0.0 2.8 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 2.9 GO:0072562 blood microparticle(GO:0072562)
0.0 4.0 GO:0031968 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 1.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
51.3 205.1 GO:0004001 adenosine kinase activity(GO:0004001)
37.1 111.4 GO:0043035 chromatin insulator sequence binding(GO:0043035)
33.8 101.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
33.7 202.3 GO:0035500 MH2 domain binding(GO:0035500)
25.1 125.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
24.6 73.7 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
23.2 92.9 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
22.5 180.4 GO:0050733 RS domain binding(GO:0050733)
21.9 87.5 GO:0033677 DNA/RNA helicase activity(GO:0033677)
21.6 86.3 GO:0070404 NADH binding(GO:0070404)
21.4 128.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
19.8 59.3 GO:0009041 uridylate kinase activity(GO:0009041)
19.4 77.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
19.1 57.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
18.8 75.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
18.2 54.5 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
17.8 89.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
17.6 105.8 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
17.5 69.9 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
17.3 173.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
16.5 66.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
16.5 49.5 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
16.3 49.0 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
16.0 128.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
15.7 31.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
15.2 137.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
14.8 59.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
14.7 191.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
14.6 73.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
14.0 140.2 GO:0033592 RNA strand annealing activity(GO:0033592)
13.7 123.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
13.7 13.7 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
13.4 67.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
13.4 93.7 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
13.3 53.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
12.9 77.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
12.8 64.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
12.5 37.5 GO:0004639 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
11.7 81.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
11.7 58.3 GO:1990460 leptin receptor binding(GO:1990460)
11.5 45.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
11.3 67.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
11.3 45.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
11.3 45.0 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
11.2 44.8 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
11.0 77.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
10.7 42.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
10.6 116.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
10.5 42.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
10.5 73.8 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
10.5 63.0 GO:0036033 mediator complex binding(GO:0036033)
10.1 130.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
10.0 30.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
9.6 38.5 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
9.5 266.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
9.4 28.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
9.0 45.0 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
8.8 44.1 GO:0042296 ISG15 transferase activity(GO:0042296)
8.6 77.8 GO:0016842 amidine-lyase activity(GO:0016842)
8.6 25.9 GO:0005046 KDEL sequence binding(GO:0005046)
8.2 123.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
8.2 48.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
8.1 437.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
7.9 118.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
7.6 76.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
7.5 149.4 GO:0008327 methyl-CpG binding(GO:0008327)
7.5 22.4 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
7.4 14.9 GO:0071532 ankyrin repeat binding(GO:0071532)
7.3 462.5 GO:0003743 translation initiation factor activity(GO:0003743)
7.0 49.2 GO:0050815 phosphoserine binding(GO:0050815)
6.9 27.8 GO:0099609 microtubule lateral binding(GO:0099609)
6.9 69.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
6.9 27.5 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
6.9 34.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
6.8 20.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
6.7 20.0 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
6.7 272.7 GO:0036002 pre-mRNA binding(GO:0036002)
6.6 33.2 GO:0005047 signal recognition particle binding(GO:0005047)
6.6 32.8 GO:0030348 syntaxin-3 binding(GO:0030348)
6.5 39.0 GO:1904288 BAT3 complex binding(GO:1904288)
6.4 70.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
6.4 102.0 GO:0000150 recombinase activity(GO:0000150)
6.3 50.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
6.3 18.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
6.3 338.5 GO:0051879 Hsp90 protein binding(GO:0051879)
6.2 112.5 GO:0017070 U6 snRNA binding(GO:0017070)
6.2 18.7 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
6.2 99.3 GO:0003746 translation elongation factor activity(GO:0003746)
6.1 24.5 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
6.1 206.8 GO:0001671 ATPase activator activity(GO:0001671)
5.9 41.6 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
5.8 40.4 GO:0030911 TPR domain binding(GO:0030911)
5.6 44.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
5.5 16.6 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
5.5 44.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
5.4 114.2 GO:0001056 RNA polymerase III activity(GO:0001056)
5.4 21.6 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
5.4 26.9 GO:0017018 myosin phosphatase activity(GO:0017018)
5.4 21.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
5.2 15.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
5.2 41.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
5.1 30.6 GO:1990763 arrestin family protein binding(GO:1990763)
5.1 183.2 GO:0051059 NF-kappaB binding(GO:0051059)
5.1 136.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
5.0 44.7 GO:0070182 DNA polymerase binding(GO:0070182)
4.9 34.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
4.9 1051.1 GO:0003735 structural constituent of ribosome(GO:0003735)
4.9 220.1 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
4.9 48.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
4.7 37.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
4.7 33.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
4.6 78.1 GO:0016018 cyclosporin A binding(GO:0016018)
4.6 27.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
4.5 89.8 GO:0070628 proteasome binding(GO:0070628)
4.5 26.9 GO:0004594 pantothenate kinase activity(GO:0004594)
4.4 155.2 GO:0043022 ribosome binding(GO:0043022)
4.3 34.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
4.2 58.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
4.1 28.7 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
4.1 171.6 GO:0004532 exoribonuclease activity(GO:0004532)
4.0 16.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
4.0 196.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
4.0 68.1 GO:0016004 phospholipase activator activity(GO:0016004)
4.0 20.0 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
4.0 147.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
3.9 116.9 GO:0046966 thyroid hormone receptor binding(GO:0046966)
3.9 65.6 GO:0042809 vitamin D receptor binding(GO:0042809)
3.9 30.8 GO:0015288 porin activity(GO:0015288)
3.7 76.9 GO:0050811 GABA receptor binding(GO:0050811)
3.6 147.5 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
3.5 104.9 GO:0008143 poly(A) binding(GO:0008143)
3.5 31.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
3.4 10.3 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
3.4 27.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
3.4 78.8 GO:0005537 mannose binding(GO:0005537)
3.4 6.8 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
3.4 13.5 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
3.3 33.1 GO:0008187 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
3.3 95.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
3.3 9.8 GO:0032090 Pyrin domain binding(GO:0032090)
3.2 9.7 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
3.1 231.1 GO:0019003 GDP binding(GO:0019003)
3.0 90.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
3.0 12.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
3.0 11.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.9 17.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
2.9 14.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
2.9 64.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
2.9 14.5 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
2.8 36.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
2.7 51.9 GO:0043495 protein anchor(GO:0043495)
2.7 10.9 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
2.7 48.9 GO:0070063 RNA polymerase binding(GO:0070063)
2.6 60.0 GO:0048156 tau protein binding(GO:0048156)
2.6 20.7 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
2.6 10.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
2.5 12.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
2.5 52.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
2.5 12.6 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
2.5 85.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
2.5 51.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
2.3 30.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
2.3 60.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.3 11.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
2.3 13.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
2.3 11.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
2.2 17.3 GO:0015232 heme transporter activity(GO:0015232)
2.1 30.8 GO:0043274 phospholipase binding(GO:0043274)
2.0 16.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
2.0 31.5 GO:0030215 semaphorin receptor binding(GO:0030215)
2.0 15.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.9 9.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
1.9 17.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.9 91.0 GO:0004364 glutathione transferase activity(GO:0004364)
1.9 42.6 GO:0042288 MHC class I protein binding(GO:0042288)
1.8 20.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.8 8.9 GO:0097016 L27 domain binding(GO:0097016)
1.7 20.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.7 6.9 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
1.7 11.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
1.6 6.4 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.6 9.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.6 14.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.6 184.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
1.5 18.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
1.5 12.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
1.5 29.7 GO:0032036 myosin heavy chain binding(GO:0032036)
1.5 41.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.5 17.5 GO:0042608 T cell receptor binding(GO:0042608)
1.4 56.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
1.4 12.9 GO:0035174 histone serine kinase activity(GO:0035174)
1.4 7.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
1.4 29.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.4 16.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
1.4 67.2 GO:0008536 Ran GTPase binding(GO:0008536)
1.4 8.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.4 144.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
1.4 6.8 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.3 14.8 GO:0016783 sulfurtransferase activity(GO:0016783)
1.3 81.1 GO:0009055 electron carrier activity(GO:0009055)
1.3 24.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.3 10.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.3 24.4 GO:0017049 GTP-Rho binding(GO:0017049)
1.3 12.8 GO:0051011 microtubule minus-end binding(GO:0051011)
1.3 12.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
1.3 5.1 GO:0008097 5S rRNA binding(GO:0008097)
1.3 41.5 GO:0015248 sterol transporter activity(GO:0015248)
1.2 19.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
1.2 71.5 GO:0005507 copper ion binding(GO:0005507)
1.2 1730.4 GO:0003723 RNA binding(GO:0003723)
1.2 13.9 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
1.1 2.3 GO:0004040 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
1.1 11.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.1 24.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.1 14.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
1.1 177.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
1.1 10.5 GO:0008408 3'-5' exonuclease activity(GO:0008408)
1.0 16.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
1.0 21.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.0 15.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
1.0 78.0 GO:0051219 phosphoprotein binding(GO:0051219)
1.0 10.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
1.0 10.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
1.0 14.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.0 2.9 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.9 69.1 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.8 59.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.8 12.5 GO:0016421 CoA carboxylase activity(GO:0016421)
0.8 4.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.8 10.3 GO:0070064 proline-rich region binding(GO:0070064)
0.8 66.3 GO:0008565 protein transporter activity(GO:0008565)
0.8 60.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.8 23.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.7 17.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.7 18.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.7 2.8 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.7 10.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.7 7.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.6 5.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.6 101.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.6 18.1 GO:0042605 peptide antigen binding(GO:0042605)
0.6 15.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.6 13.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.6 3.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.4 10.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.4 2.2 GO:0034452 dynactin binding(GO:0034452)
0.4 3.8 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.4 53.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 19.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.4 1.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.4 7.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 1.9 GO:0019776 Atg8 ligase activity(GO:0019776)
0.4 6.0 GO:0016208 AMP binding(GO:0016208)
0.3 56.4 GO:0008201 heparin binding(GO:0008201)
0.3 5.1 GO:0070410 co-SMAD binding(GO:0070410)
0.3 1.9 GO:0039706 co-receptor binding(GO:0039706)
0.3 5.7 GO:0005522 profilin binding(GO:0005522)
0.3 3.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.3 0.3 GO:0043398 HLH domain binding(GO:0043398)
0.3 109.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.3 20.5 GO:0008237 metallopeptidase activity(GO:0008237)
0.2 28.1 GO:0005178 integrin binding(GO:0005178)
0.2 10.8 GO:0051087 chaperone binding(GO:0051087)
0.2 1.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 3.0 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.7 GO:0043426 MRF binding(GO:0043426)
0.2 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 2.2 GO:0035497 cAMP response element binding(GO:0035497)
0.2 7.9 GO:0050699 WW domain binding(GO:0050699)
0.2 2.8 GO:0070840 dynein complex binding(GO:0070840)
0.2 8.0 GO:0032947 protein complex scaffold(GO:0032947)
0.1 1.0 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 2.2 GO:0043531 ADP binding(GO:0043531)
0.1 7.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 4.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 2.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 0.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 15.9 GO:0003924 GTPase activity(GO:0003924)
0.1 17.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 4.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 2.4 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 3.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 6.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 7.6 GO:0015293 symporter activity(GO:0015293)
0.0 0.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 2.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.5 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 191.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
6.8 394.0 PID AURORA B PATHWAY Aurora B signaling
6.7 322.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
5.5 105.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
5.0 115.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
4.9 151.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
4.8 308.3 PID PLK1 PATHWAY PLK1 signaling events
4.2 88.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
3.6 158.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
3.5 114.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
3.0 33.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
3.0 117.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
2.8 53.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
2.7 96.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
2.7 284.9 PID TELOMERASE PATHWAY Regulation of Telomerase
2.6 72.4 PID FANCONI PATHWAY Fanconi anemia pathway
2.4 124.3 SIG CHEMOTAXIS Genes related to chemotaxis
2.3 140.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
2.3 16.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
2.3 73.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
2.3 102.5 PID IL1 PATHWAY IL1-mediated signaling events
2.3 47.8 PID NECTIN PATHWAY Nectin adhesion pathway
2.3 61.2 PID AURORA A PATHWAY Aurora A signaling
1.9 32.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
1.9 211.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
1.8 33.2 PID IL3 PATHWAY IL3-mediated signaling events
1.8 14.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.8 10.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
1.6 54.8 PID TRAIL PATHWAY TRAIL signaling pathway
1.6 46.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
1.4 92.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
1.4 251.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
1.3 53.6 PID NCADHERIN PATHWAY N-cadherin signaling events
1.3 81.3 PID E2F PATHWAY E2F transcription factor network
1.2 89.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
1.2 24.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
1.2 109.3 PID CMYB PATHWAY C-MYB transcription factor network
1.2 20.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
1.1 63.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
1.1 26.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
1.1 39.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
1.0 2.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.8 43.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.8 35.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.8 24.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.8 15.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.8 36.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.7 15.7 PID IFNG PATHWAY IFN-gamma pathway
0.7 23.1 PID FOXO PATHWAY FoxO family signaling
0.7 19.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.7 36.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.6 13.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.6 32.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 21.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.4 19.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.4 10.6 ST GA13 PATHWAY G alpha 13 Pathway
0.4 9.6 PID P53 REGULATION PATHWAY p53 pathway
0.4 24.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.3 21.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 8.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 4.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 4.0 PID ATM PATHWAY ATM pathway
0.2 9.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 8.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 5.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.8 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
24.5 220.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
19.6 19.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
12.9 116.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
10.4 757.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
9.2 821.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
8.5 205.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
8.5 93.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
8.0 144.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
7.7 131.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
7.7 115.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
7.5 367.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
7.3 262.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
7.2 86.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
7.0 245.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
6.8 75.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
6.6 59.6 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
6.6 39.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
6.6 91.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
6.4 470.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
6.2 136.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
5.9 153.8 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
5.9 94.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
5.8 57.7 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
5.5 60.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
5.5 223.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
5.4 114.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
5.3 90.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
5.2 337.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
5.1 40.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
5.0 181.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
5.0 667.0 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
5.0 90.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
4.8 751.7 REACTOME TRANSLATION Genes involved in Translation
4.5 35.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
4.4 145.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
4.2 66.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
4.1 202.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
4.1 114.3 REACTOME KINESINS Genes involved in Kinesins
4.1 40.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
3.9 35.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
3.9 129.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
3.9 158.7 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
3.8 49.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
3.5 49.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
3.4 20.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
3.4 53.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
3.3 76.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
3.2 6.4 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
3.1 34.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
2.9 87.4 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
2.9 34.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
2.9 65.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
2.9 14.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
2.8 78.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
2.8 416.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
2.7 19.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
2.7 51.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
2.7 86.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
2.7 35.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
2.6 31.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
2.5 81.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
2.5 102.9 REACTOME G1 PHASE Genes involved in G1 Phase
2.4 142.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
2.1 38.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
2.1 79.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
2.0 26.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
2.0 57.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
2.0 29.6 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
1.9 19.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
1.8 44.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
1.8 23.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
1.7 52.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
1.6 49.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.6 19.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
1.5 34.7 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
1.5 17.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.4 39.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.4 30.7 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
1.4 89.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
1.4 27.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
1.3 26.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
1.2 29.6 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
1.2 39.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
1.2 18.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
1.2 24.0 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
1.1 63.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
1.1 9.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
1.1 87.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
1.0 16.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
1.0 17.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.9 23.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.9 33.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.8 36.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.8 6.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.8 43.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.8 45.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.7 11.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.5 12.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 30.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.4 15.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 3.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.4 16.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 11.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.3 7.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 9.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 23.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 11.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 6.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 5.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 8.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 7.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 15.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.2 1.5 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.2 32.0 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 1.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 6.4 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 1.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 3.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 6.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants