Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for TBX1
Z-value: 6.31
Motif logo
Transcription factors associated with TBX1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TBX1
|
ENSG00000184058.15 | TBX1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TBX1 | hg38_v1_chr22_+_19760714_19760794 | 0.36 | 5.2e-08 | Click! |
Activity profile of TBX1 motif
Sorted Z-values of TBX1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of TBX1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 15.9 | GO:0060005 | vestibular reflex(GO:0060005) |
| 5.3 | 26.3 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 3.4 | 13.8 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 3.3 | 13.3 | GO:1902023 | L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023) |
| 3.3 | 10.0 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
| 3.3 | 9.8 | GO:2000777 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777) |
| 3.2 | 12.8 | GO:0002370 | natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) |
| 3.1 | 15.7 | GO:1902998 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 3.0 | 14.8 | GO:2000870 | oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870) |
| 2.9 | 14.5 | GO:0046103 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 2.7 | 8.2 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 2.5 | 7.6 | GO:0090341 | negative regulation of secretion of lysosomal enzymes(GO:0090341) |
| 2.4 | 2.4 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 2.3 | 9.3 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 2.3 | 16.2 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 2.3 | 46.0 | GO:0097242 | beta-amyloid clearance(GO:0097242) |
| 2.2 | 6.5 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) |
| 2.2 | 6.5 | GO:0021538 | epithalamus development(GO:0021538) habenula development(GO:0021986) |
| 2.1 | 2.1 | GO:0014724 | regulation of twitch skeletal muscle contraction(GO:0014724) |
| 2.1 | 12.4 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 2.1 | 6.2 | GO:0060032 | notochord regression(GO:0060032) |
| 2.1 | 10.3 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) |
| 2.0 | 12.2 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 2.0 | 6.0 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 2.0 | 5.9 | GO:0061011 | hepatic duct development(GO:0061011) |
| 1.9 | 5.7 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 1.8 | 16.3 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 1.8 | 5.4 | GO:0009720 | detection of hormone stimulus(GO:0009720) |
| 1.8 | 5.3 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 1.8 | 5.3 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 1.7 | 5.2 | GO:0042231 | interleukin-13 biosynthetic process(GO:0042231) |
| 1.7 | 5.2 | GO:0051710 | regulation of cytolysis in other organism(GO:0051710) |
| 1.6 | 1.6 | GO:0045588 | positive regulation of gamma-delta T cell differentiation(GO:0045588) |
| 1.6 | 9.8 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 1.6 | 6.4 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 1.6 | 4.8 | GO:0051039 | histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 1.6 | 4.7 | GO:2001226 | negative regulation of chloride transport(GO:2001226) |
| 1.5 | 9.0 | GO:0002679 | respiratory burst involved in defense response(GO:0002679) |
| 1.5 | 4.5 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
| 1.5 | 10.4 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 1.5 | 4.4 | GO:2000566 | positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566) |
| 1.4 | 8.6 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 1.4 | 18.5 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
| 1.4 | 12.5 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 1.4 | 5.5 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 1.4 | 5.5 | GO:0002357 | defense response to tumor cell(GO:0002357) |
| 1.4 | 5.5 | GO:2000851 | positive regulation of glucocorticoid secretion(GO:2000851) |
| 1.4 | 2.7 | GO:0090182 | regulation of secretion of lysosomal enzymes(GO:0090182) |
| 1.3 | 5.4 | GO:1902617 | response to fluoride(GO:1902617) |
| 1.3 | 2.7 | GO:0005988 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 1.3 | 4.0 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 1.3 | 10.6 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 1.3 | 5.3 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 1.2 | 13.7 | GO:0006032 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 1.2 | 11.1 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 1.2 | 4.9 | GO:0072011 | glomerular endothelium development(GO:0072011) |
| 1.2 | 4.8 | GO:0032764 | negative regulation of mast cell cytokine production(GO:0032764) |
| 1.2 | 10.7 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 1.2 | 5.9 | GO:0044856 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 1.2 | 4.7 | GO:1904823 | pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823) |
| 1.2 | 5.8 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 1.2 | 12.7 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 1.1 | 9.2 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
| 1.1 | 3.4 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 1.1 | 3.4 | GO:0042701 | progesterone secretion(GO:0042701) |
| 1.1 | 2.3 | GO:0015860 | purine nucleoside transmembrane transport(GO:0015860) |
| 1.1 | 2.2 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 1.1 | 2.2 | GO:0046110 | xanthine metabolic process(GO:0046110) |
| 1.1 | 5.5 | GO:0009732 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
| 1.1 | 8.8 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 1.1 | 7.6 | GO:0032466 | negative regulation of cytokinesis(GO:0032466) |
| 1.1 | 6.5 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 1.0 | 1.0 | GO:0032752 | positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) |
| 1.0 | 5.2 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 1.0 | 4.1 | GO:0071317 | negative regulation of Wnt protein secretion(GO:0061358) cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317) |
| 1.0 | 3.1 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 1.0 | 6.1 | GO:0048241 | epinephrine transport(GO:0048241) |
| 1.0 | 6.0 | GO:0050893 | sensory processing(GO:0050893) |
| 1.0 | 6.9 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 1.0 | 3.0 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 1.0 | 3.9 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 1.0 | 6.9 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 1.0 | 3.9 | GO:0002881 | negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881) |
| 1.0 | 4.9 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 1.0 | 7.8 | GO:0015747 | urate transport(GO:0015747) |
| 1.0 | 3.9 | GO:0045626 | negative regulation of T-helper 1 cell differentiation(GO:0045626) |
| 1.0 | 3.8 | GO:1900191 | biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) positive regulation of chondrocyte proliferation(GO:1902732) |
| 0.9 | 6.6 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.9 | 2.8 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) nucleobase catabolic process(GO:0046113) |
| 0.9 | 2.8 | GO:1903937 | response to acrylamide(GO:1903937) |
| 0.9 | 6.5 | GO:1990822 | basic amino acid transmembrane transport(GO:1990822) |
| 0.9 | 7.4 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.9 | 2.7 | GO:0036146 | cellular response to mycotoxin(GO:0036146) response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025) |
| 0.9 | 2.7 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
| 0.9 | 10.8 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.9 | 6.2 | GO:1902731 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731) |
| 0.9 | 24.8 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.9 | 0.9 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.9 | 7.0 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.9 | 4.4 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.9 | 14.6 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 0.9 | 2.6 | GO:1900186 | negative regulation of clathrin-mediated endocytosis(GO:1900186) |
| 0.9 | 4.3 | GO:0035655 | interleukin-18-mediated signaling pathway(GO:0035655) |
| 0.9 | 5.1 | GO:0045976 | negative regulation of mitotic cell cycle, embryonic(GO:0045976) |
| 0.9 | 3.4 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.9 | 2.6 | GO:0042495 | detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) |
| 0.8 | 9.3 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.8 | 5.9 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
| 0.8 | 2.5 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) sarcomerogenesis(GO:0048769) |
| 0.8 | 3.4 | GO:0046968 | peptide antigen transport(GO:0046968) |
| 0.8 | 4.2 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.8 | 2.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.8 | 4.1 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.8 | 2.4 | GO:0046104 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 0.8 | 6.4 | GO:0051121 | hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) |
| 0.8 | 4.7 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 0.8 | 9.4 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.8 | 2.4 | GO:0070846 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.8 | 3.1 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
| 0.8 | 4.6 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.8 | 2.3 | GO:0042137 | sequestering of neurotransmitter(GO:0042137) |
| 0.8 | 5.3 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) |
| 0.8 | 2.3 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.8 | 3.0 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
| 0.8 | 7.6 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.8 | 1.5 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 0.7 | 2.2 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 0.7 | 9.7 | GO:0043046 | DNA methylation involved in gamete generation(GO:0043046) |
| 0.7 | 6.7 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.7 | 2.2 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.7 | 4.4 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
| 0.7 | 2.9 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.7 | 2.9 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.7 | 2.9 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.7 | 2.2 | GO:1904328 | positive regulation of platelet aggregation(GO:1901731) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 0.7 | 2.8 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
| 0.7 | 4.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.7 | 2.1 | GO:0060448 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
| 0.7 | 1.4 | GO:2000389 | regulation of neutrophil extravasation(GO:2000389) |
| 0.7 | 8.3 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.7 | 7.5 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.7 | 1.3 | GO:0018963 | phthalate metabolic process(GO:0018963) |
| 0.7 | 2.0 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.7 | 18.1 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.7 | 3.3 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.7 | 2.0 | GO:0098758 | response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) |
| 0.7 | 2.0 | GO:0007343 | egg activation(GO:0007343) |
| 0.7 | 28.5 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.7 | 1.3 | GO:0048850 | hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852) |
| 0.7 | 2.0 | GO:0030573 | bile acid catabolic process(GO:0030573) |
| 0.7 | 9.8 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.7 | 3.9 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.7 | 1.3 | GO:0035962 | response to interleukin-13(GO:0035962) |
| 0.6 | 1.9 | GO:0042938 | dipeptide transport(GO:0042938) |
| 0.6 | 3.8 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.6 | 3.8 | GO:0043366 | beta selection(GO:0043366) |
| 0.6 | 10.1 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.6 | 5.0 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.6 | 6.9 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.6 | 2.5 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.6 | 2.5 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.6 | 6.2 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.6 | 3.7 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.6 | 1.8 | GO:0030186 | melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) |
| 0.6 | 9.0 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 0.6 | 16.7 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.6 | 1.8 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 0.6 | 8.3 | GO:0060285 | inner dynein arm assembly(GO:0036159) cilium-dependent cell motility(GO:0060285) |
| 0.6 | 7.7 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.6 | 2.9 | GO:0086048 | membrane depolarization during bundle of His cell action potential(GO:0086048) |
| 0.6 | 2.3 | GO:1904800 | negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173) |
| 0.6 | 5.1 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.6 | 10.3 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.6 | 5.7 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.6 | 5.1 | GO:0030807 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) |
| 0.6 | 7.8 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.6 | 3.9 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.6 | 2.2 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.6 | 1.7 | GO:2000830 | vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830) |
| 0.6 | 2.8 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 0.5 | 1.6 | GO:1901162 | primary amino compound biosynthetic process(GO:1901162) |
| 0.5 | 4.3 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.5 | 1.6 | GO:1904692 | positive regulation of type B pancreatic cell proliferation(GO:1904692) |
| 0.5 | 1.1 | GO:0032242 | regulation of nucleoside transport(GO:0032242) |
| 0.5 | 6.9 | GO:1901078 | negative regulation of relaxation of muscle(GO:1901078) |
| 0.5 | 1.1 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.5 | 5.3 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.5 | 3.2 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.5 | 1.6 | GO:0061591 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
| 0.5 | 0.5 | GO:0099525 | presynaptic dense core granule exocytosis(GO:0099525) |
| 0.5 | 6.8 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
| 0.5 | 4.2 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.5 | 2.1 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.5 | 1.0 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.5 | 5.7 | GO:0021513 | spinal cord dorsal/ventral patterning(GO:0021513) |
| 0.5 | 2.6 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.5 | 3.6 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.5 | 2.6 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.5 | 4.1 | GO:0070236 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.5 | 3.5 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 0.5 | 5.0 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.5 | 3.5 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.5 | 8.9 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.5 | 2.0 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 0.5 | 3.4 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
| 0.5 | 2.5 | GO:0086043 | bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) |
| 0.5 | 6.3 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.5 | 11.2 | GO:0042789 | mRNA transcription from RNA polymerase II promoter(GO:0042789) |
| 0.5 | 1.0 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) |
| 0.5 | 4.8 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.5 | 1.9 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.5 | 1.0 | GO:0032489 | regulation of Cdc42 protein signal transduction(GO:0032489) |
| 0.5 | 1.0 | GO:0043400 | cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462) |
| 0.5 | 3.3 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.5 | 3.8 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.5 | 5.7 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.5 | 1.4 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.5 | 2.3 | GO:0038001 | paracrine signaling(GO:0038001) |
| 0.5 | 7.4 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.5 | 2.3 | GO:0042761 | fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 0.5 | 1.4 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
| 0.5 | 2.7 | GO:0002005 | angiotensin catabolic process in blood(GO:0002005) |
| 0.4 | 1.3 | GO:0038027 | apolipoprotein A-I-mediated signaling pathway(GO:0038027) negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
| 0.4 | 7.5 | GO:0071028 | nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
| 0.4 | 9.3 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
| 0.4 | 0.9 | GO:0070433 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) |
| 0.4 | 2.2 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.4 | 2.2 | GO:0010813 | neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.4 | 3.9 | GO:0072540 | T-helper 17 cell lineage commitment(GO:0072540) |
| 0.4 | 2.6 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 0.4 | 2.6 | GO:0010732 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 0.4 | 4.7 | GO:0048007 | antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.4 | 0.9 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.4 | 3.8 | GO:2000400 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.4 | 2.5 | GO:0070495 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.4 | 5.9 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.4 | 3.4 | GO:0003402 | planar cell polarity pathway involved in axis elongation(GO:0003402) |
| 0.4 | 8.0 | GO:0034122 | negative regulation of toll-like receptor signaling pathway(GO:0034122) |
| 0.4 | 1.7 | GO:0042361 | menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377) |
| 0.4 | 1.7 | GO:1904640 | response to methionine(GO:1904640) |
| 0.4 | 8.4 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.4 | 2.1 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.4 | 2.5 | GO:1902514 | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.4 | 4.6 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
| 0.4 | 1.2 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 0.4 | 2.1 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.4 | 10.7 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.4 | 4.1 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.4 | 1.2 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 0.4 | 4.1 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.4 | 4.5 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.4 | 1.2 | GO:0034653 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
| 0.4 | 3.2 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.4 | 4.8 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.4 | 4.4 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
| 0.4 | 5.6 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.4 | 2.8 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.4 | 3.6 | GO:0045046 | protein import into peroxisome membrane(GO:0045046) |
| 0.4 | 2.0 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.4 | 1.6 | GO:0032306 | regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) |
| 0.4 | 3.5 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.4 | 3.9 | GO:0001767 | establishment of lymphocyte polarity(GO:0001767) |
| 0.4 | 0.8 | GO:0033504 | floor plate development(GO:0033504) |
| 0.4 | 7.7 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 0.4 | 0.8 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.4 | 4.2 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
| 0.4 | 1.9 | GO:0038169 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 0.4 | 1.1 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.4 | 6.1 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.4 | 7.5 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.4 | 3.4 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.4 | 1.9 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 0.4 | 4.1 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.4 | 3.0 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.4 | 0.4 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
| 0.4 | 2.9 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.4 | 10.0 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.4 | 3.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.4 | 1.1 | GO:0051541 | elastin metabolic process(GO:0051541) |
| 0.3 | 2.8 | GO:0071799 | response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799) |
| 0.3 | 1.0 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.3 | 2.1 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.3 | 0.7 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.3 | 2.4 | GO:0015705 | iodide transport(GO:0015705) |
| 0.3 | 1.0 | GO:1901964 | apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) deltoid tuberosity development(GO:0035993) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) |
| 0.3 | 4.0 | GO:0015871 | choline transport(GO:0015871) |
| 0.3 | 12.1 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.3 | 2.0 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 0.3 | 1.0 | GO:0070673 | response to interleukin-18(GO:0070673) |
| 0.3 | 1.3 | GO:0060327 | cytoplasmic actin-based contraction involved in cell motility(GO:0060327) |
| 0.3 | 2.0 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.3 | 2.3 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.3 | 2.3 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.3 | 6.2 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.3 | 10.3 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.3 | 7.1 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.3 | 7.7 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.3 | 3.8 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.3 | 2.2 | GO:0009134 | nucleoside diphosphate catabolic process(GO:0009134) |
| 0.3 | 2.9 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.3 | 6.0 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.3 | 0.9 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.3 | 1.9 | GO:2001205 | negative regulation of osteoclast development(GO:2001205) |
| 0.3 | 2.2 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 0.3 | 0.6 | GO:0099624 | atrial cardiac muscle cell membrane repolarization(GO:0099624) |
| 0.3 | 0.9 | GO:1904021 | regulation of G-protein coupled receptor internalization(GO:1904020) negative regulation of G-protein coupled receptor internalization(GO:1904021) |
| 0.3 | 5.9 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.3 | 5.0 | GO:0044065 | regulation of respiratory system process(GO:0044065) |
| 0.3 | 1.2 | GO:0046015 | regulation of transcription by glucose(GO:0046015) |
| 0.3 | 0.9 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.3 | 2.1 | GO:1904098 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.3 | 0.9 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.3 | 4.0 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.3 | 31.9 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 0.3 | 2.1 | GO:0045007 | depurination(GO:0045007) |
| 0.3 | 24.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.3 | 11.4 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.3 | 2.1 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.3 | 2.7 | GO:0007512 | adult heart development(GO:0007512) |
| 0.3 | 1.5 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.3 | 0.6 | GO:0033690 | positive regulation of osteoblast proliferation(GO:0033690) |
| 0.3 | 3.2 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.3 | 1.7 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.3 | 0.9 | GO:0046603 | negative regulation of mitotic centrosome separation(GO:0046603) |
| 0.3 | 0.9 | GO:0072023 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.3 | 2.3 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.3 | 1.7 | GO:1900426 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) positive regulation of defense response to bacterium(GO:1900426) |
| 0.3 | 1.1 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.3 | 2.0 | GO:1903433 | regulation of constitutive secretory pathway(GO:1903433) |
| 0.3 | 7.1 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.3 | 6.0 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.3 | 1.4 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
| 0.3 | 5.9 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.3 | 3.5 | GO:0044116 | growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) |
| 0.3 | 5.3 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.3 | 5.0 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.3 | 1.8 | GO:0046950 | cellular ketone body metabolic process(GO:0046950) |
| 0.3 | 3.1 | GO:0032366 | intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367) |
| 0.3 | 2.1 | GO:0055129 | proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129) |
| 0.3 | 1.0 | GO:0032900 | viral protein processing(GO:0019082) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472) |
| 0.3 | 1.8 | GO:0002923 | regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.3 | 4.8 | GO:2000169 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169) |
| 0.3 | 1.5 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.3 | 1.8 | GO:0098856 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.2 | 1.5 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.2 | 1.2 | GO:0034182 | regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) |
| 0.2 | 6.7 | GO:0019835 | cytolysis(GO:0019835) |
| 0.2 | 1.2 | GO:0042636 | negative regulation of hair cycle(GO:0042636) |
| 0.2 | 2.2 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.2 | 1.7 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.2 | 2.9 | GO:0002717 | positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
| 0.2 | 2.9 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.2 | 3.6 | GO:0006071 | glycerol metabolic process(GO:0006071) |
| 0.2 | 0.7 | GO:0042723 | thiamine-containing compound metabolic process(GO:0042723) |
| 0.2 | 1.4 | GO:0061525 | hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525) |
| 0.2 | 4.1 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.2 | 4.0 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.2 | 3.5 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.2 | 3.9 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.2 | 2.7 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.2 | 1.4 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.2 | 6.3 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.2 | 3.8 | GO:0042953 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.2 | 2.2 | GO:0010529 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
| 0.2 | 3.8 | GO:0031065 | positive regulation of histone deacetylation(GO:0031065) |
| 0.2 | 0.9 | GO:0032431 | activation of phospholipase A2 activity(GO:0032431) |
| 0.2 | 16.8 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.2 | 1.1 | GO:0001575 | globoside metabolic process(GO:0001575) |
| 0.2 | 1.8 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.2 | 1.7 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.2 | 21.8 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.2 | 15.3 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.2 | 1.5 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
| 0.2 | 5.4 | GO:0048536 | spleen development(GO:0048536) |
| 0.2 | 3.0 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.2 | 0.9 | GO:0097369 | sodium ion import(GO:0097369) |
| 0.2 | 1.1 | GO:2000852 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 0.2 | 0.8 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.2 | 2.3 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.2 | 2.3 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.2 | 0.8 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.2 | 1.7 | GO:0030091 | protein repair(GO:0030091) |
| 0.2 | 5.2 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.2 | 2.1 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.2 | 3.5 | GO:0023058 | adaptation of signaling pathway(GO:0023058) |
| 0.2 | 3.1 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.2 | 3.5 | GO:0045199 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.2 | 1.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.2 | 1.8 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.2 | 2.6 | GO:0018342 | protein prenylation(GO:0018342) prenylation(GO:0097354) |
| 0.2 | 0.6 | GO:0044241 | lipid digestion(GO:0044241) |
| 0.2 | 12.8 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.2 | 9.8 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.2 | 0.8 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 0.2 | 2.3 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.2 | 3.3 | GO:0030220 | platelet formation(GO:0030220) |
| 0.2 | 1.1 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.2 | 1.0 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.2 | 0.6 | GO:0035054 | embryonic heart tube anterior/posterior pattern specification(GO:0035054) |
| 0.2 | 8.2 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.2 | 3.8 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) |
| 0.2 | 0.9 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.2 | 2.4 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.2 | 0.9 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.2 | 1.1 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 2.7 | GO:0006693 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.2 | 0.5 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
| 0.2 | 1.5 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.2 | 0.5 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) |
| 0.2 | 5.4 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.2 | 1.3 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.2 | 4.8 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.2 | 0.5 | GO:0018874 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 0.2 | 3.0 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.2 | 1.0 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.2 | 6.8 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.2 | 1.6 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.2 | 0.9 | GO:1904058 | positive regulation of sensory perception of pain(GO:1904058) |
| 0.2 | 3.9 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.2 | 4.3 | GO:0048485 | sympathetic nervous system development(GO:0048485) |
| 0.2 | 0.8 | GO:0005997 | xylulose metabolic process(GO:0005997) |
| 0.2 | 0.7 | GO:0097021 | lymphocyte migration into lymphoid organs(GO:0097021) |
| 0.2 | 2.3 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.2 | 2.3 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.2 | 3.6 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.2 | 1.3 | GO:0071267 | amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267) |
| 0.2 | 0.6 | GO:0021888 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 0.2 | 2.4 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.2 | 1.3 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
| 0.2 | 1.3 | GO:0044320 | cellular response to leptin stimulus(GO:0044320) |
| 0.2 | 1.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.2 | 1.8 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.2 | 4.7 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.2 | 0.3 | GO:0050748 | regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) negative regulation of lipoprotein metabolic process(GO:0050748) |
| 0.2 | 0.8 | GO:1904566 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.2 | 2.0 | GO:0019317 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.1 | 6.4 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.1 | 1.0 | GO:0010623 | programmed cell death involved in cell development(GO:0010623) |
| 0.1 | 2.2 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.1 | 0.7 | GO:0036101 | leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569) |
| 0.1 | 3.6 | GO:0072311 | renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
| 0.1 | 2.2 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 6.8 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.1 | 5.8 | GO:0045652 | regulation of megakaryocyte differentiation(GO:0045652) |
| 0.1 | 4.8 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.1 | 1.0 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.1 | 0.1 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.1 | 3.4 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
| 0.1 | 1.2 | GO:0046596 | regulation of viral entry into host cell(GO:0046596) |
| 0.1 | 0.4 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.1 | 2.2 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
| 0.1 | 2.1 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.1 | 1.9 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.1 | 2.6 | GO:0016048 | detection of temperature stimulus(GO:0016048) |
| 0.1 | 2.3 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.1 | 3.8 | GO:0006896 | Golgi to vacuole transport(GO:0006896) |
| 0.1 | 3.2 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.1 | 1.1 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.1 | 2.5 | GO:0071168 | protein localization to chromatin(GO:0071168) |
| 0.1 | 0.2 | GO:1904180 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
| 0.1 | 1.7 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.1 | 1.2 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.1 | 3.2 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 0.6 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
| 0.1 | 1.4 | GO:0015884 | folic acid transport(GO:0015884) |
| 0.1 | 0.5 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.1 | 4.0 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.1 | 0.9 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.1 | 2.9 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.1 | 2.4 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.1 | 3.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 0.4 | GO:0050712 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
| 0.1 | 0.5 | GO:0015692 | lead ion transport(GO:0015692) |
| 0.1 | 1.6 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 1.5 | GO:0010919 | regulation of inositol phosphate biosynthetic process(GO:0010919) |
| 0.1 | 0.6 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.1 | 11.7 | GO:0071346 | cellular response to interferon-gamma(GO:0071346) |
| 0.1 | 0.2 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.1 | 0.4 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 0.1 | 1.9 | GO:0038202 | TORC1 signaling(GO:0038202) |
| 0.1 | 1.0 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.1 | 0.9 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.1 | 2.7 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 2.7 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
| 0.1 | 1.9 | GO:0071320 | cellular response to cAMP(GO:0071320) |
| 0.1 | 5.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.1 | 2.1 | GO:0001945 | lymph vessel development(GO:0001945) |
| 0.1 | 4.9 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 1.0 | GO:0072348 | sulfur compound transport(GO:0072348) |
| 0.1 | 6.2 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.1 | 0.5 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.1 | 0.2 | GO:0097112 | gamma-aminobutyric acid receptor clustering(GO:0097112) |
| 0.1 | 3.1 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
| 0.1 | 1.6 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.1 | 1.1 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.1 | 1.9 | GO:2000036 | regulation of stem cell population maintenance(GO:2000036) |
| 0.1 | 0.5 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.1 | 6.8 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.1 | 3.4 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.1 | 0.3 | GO:0010716 | negative regulation of extracellular matrix disassembly(GO:0010716) |
| 0.1 | 0.9 | GO:0003341 | cilium movement(GO:0003341) |
| 0.1 | 3.4 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.1 | 2.2 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.1 | 0.7 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.1 | 2.7 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.1 | 4.5 | GO:0009953 | dorsal/ventral pattern formation(GO:0009953) |
| 0.1 | 0.5 | GO:0019441 | tryptophan catabolic process to kynurenine(GO:0019441) |
| 0.1 | 1.6 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.1 | 1.7 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.1 | 1.8 | GO:0009583 | detection of light stimulus(GO:0009583) |
| 0.1 | 1.2 | GO:0045821 | positive regulation of glycolytic process(GO:0045821) |
| 0.1 | 2.5 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.1 | 0.8 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.1 | 0.5 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.1 | 0.3 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.1 | 0.1 | GO:0002331 | pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331) |
| 0.1 | 1.5 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.1 | 4.1 | GO:0030218 | erythrocyte differentiation(GO:0030218) |
| 0.1 | 1.3 | GO:0035082 | axoneme assembly(GO:0035082) |
| 0.1 | 2.1 | GO:0050906 | detection of stimulus involved in sensory perception(GO:0050906) |
| 0.1 | 2.5 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.1 | 0.6 | GO:0001702 | gastrulation with mouth forming second(GO:0001702) |
| 0.1 | 10.6 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.1 | 4.4 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.1 | 0.9 | GO:1902475 | L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.1 | 1.1 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.1 | 10.0 | GO:0060271 | cilium morphogenesis(GO:0060271) |
| 0.1 | 12.5 | GO:0002250 | adaptive immune response(GO:0002250) |
| 0.1 | 0.7 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.1 | 0.8 | GO:0031646 | positive regulation of myelination(GO:0031643) positive regulation of neurological system process(GO:0031646) |
| 0.1 | 1.4 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.1 | 1.7 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.1 | 0.6 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 1.1 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.0 | 1.8 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.8 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.0 | 1.0 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.0 | 0.7 | GO:0031640 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.0 | 0.4 | GO:0071313 | cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415) |
| 0.0 | 0.5 | GO:0070445 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
| 0.0 | 1.0 | GO:0045026 | plasma membrane fusion(GO:0045026) |
| 0.0 | 0.3 | GO:0021830 | interneuron migration from the subpallium to the cortex(GO:0021830) |
| 0.0 | 0.7 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.0 | 0.1 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.0 | 0.8 | GO:0097502 | mannosylation(GO:0097502) |
| 0.0 | 0.6 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.0 | 0.6 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.0 | 2.2 | GO:0031214 | biomineral tissue development(GO:0031214) |
| 0.0 | 0.7 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 1.5 | GO:0008585 | female gonad development(GO:0008585) |
| 0.0 | 0.2 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.0 | 0.7 | GO:0035411 | catenin import into nucleus(GO:0035411) |
| 0.0 | 0.2 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 15.1 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.0 | 0.3 | GO:1902916 | positive regulation of protein polyubiquitination(GO:1902916) |
| 0.0 | 0.9 | GO:0034113 | heterotypic cell-cell adhesion(GO:0034113) |
| 0.0 | 0.5 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.0 | 0.1 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.0 | 0.3 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
| 0.0 | 0.1 | GO:0030320 | cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) |
| 0.0 | 0.3 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.3 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.0 | 0.2 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.0 | 0.3 | GO:0008542 | visual learning(GO:0008542) |
| 0.0 | 0.5 | GO:0051591 | response to cAMP(GO:0051591) |
| 0.0 | 1.0 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 0.1 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.0 | 0.2 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.2 | GO:0051923 | sulfation(GO:0051923) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.3 | 41.6 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
| 4.6 | 4.6 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 4.1 | 24.4 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 3.4 | 13.8 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 3.1 | 9.4 | GO:0071752 | dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) |
| 2.1 | 14.5 | GO:1990130 | Iml1 complex(GO:1990130) |
| 2.0 | 9.8 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 1.9 | 5.8 | GO:0036027 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 1.8 | 5.3 | GO:0032426 | stereocilium tip(GO:0032426) |
| 1.7 | 1.7 | GO:0071748 | IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751) |
| 1.6 | 1.6 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 1.5 | 7.6 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 1.5 | 9.0 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
| 1.4 | 22.9 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 1.4 | 6.9 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 1.3 | 10.7 | GO:0035976 | AP1 complex(GO:0035976) |
| 1.3 | 4.0 | GO:0044609 | DBIRD complex(GO:0044609) |
| 1.2 | 8.6 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 1.2 | 11.0 | GO:0001520 | outer dense fiber(GO:0001520) |
| 1.2 | 3.5 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 1.1 | 10.1 | GO:0070652 | HAUS complex(GO:0070652) |
| 1.1 | 2.2 | GO:1990393 | 3M complex(GO:1990393) |
| 1.1 | 3.2 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 1.0 | 7.2 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 1.0 | 3.1 | GO:0005760 | gamma DNA polymerase complex(GO:0005760) |
| 1.0 | 15.3 | GO:0001741 | XY body(GO:0001741) |
| 0.9 | 3.7 | GO:0002139 | stereocilia coupling link(GO:0002139) |
| 0.9 | 18.1 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.9 | 11.3 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.9 | 2.6 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 0.8 | 4.2 | GO:0089701 | U2AF(GO:0089701) |
| 0.8 | 5.8 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.8 | 3.3 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 0.8 | 4.0 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.8 | 4.0 | GO:0044308 | axonal spine(GO:0044308) |
| 0.8 | 5.5 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.8 | 3.8 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.8 | 5.3 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.8 | 28.6 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.7 | 4.4 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.7 | 7.8 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.7 | 2.8 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.7 | 2.1 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.7 | 8.3 | GO:0005858 | axonemal dynein complex(GO:0005858) |
| 0.7 | 2.1 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.7 | 6.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.7 | 2.0 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.7 | 7.4 | GO:0005638 | lamin filament(GO:0005638) |
| 0.7 | 8.6 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.7 | 25.1 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.6 | 3.8 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
| 0.6 | 3.0 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.6 | 8.9 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.6 | 1.7 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.5 | 3.8 | GO:0032021 | NELF complex(GO:0032021) |
| 0.5 | 9.2 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.5 | 2.0 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 0.5 | 20.0 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.5 | 2.5 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.5 | 3.0 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.5 | 4.9 | GO:0016460 | myosin II complex(GO:0016460) |
| 0.5 | 2.4 | GO:0000835 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.5 | 9.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.5 | 2.8 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.5 | 3.2 | GO:1990745 | EARP complex(GO:1990745) |
| 0.4 | 4.9 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.4 | 6.2 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.4 | 1.3 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.4 | 12.2 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.4 | 20.5 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.4 | 2.2 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 0.4 | 2.9 | GO:0001939 | female pronucleus(GO:0001939) |
| 0.4 | 2.5 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.4 | 9.1 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.4 | 2.4 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.4 | 3.2 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.4 | 2.3 | GO:0060199 | clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) |
| 0.4 | 3.7 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.4 | 2.2 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.4 | 1.4 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.4 | 4.2 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.4 | 2.8 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.3 | 1.7 | GO:0045240 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) dihydrolipoyl dehydrogenase complex(GO:0045240) |
| 0.3 | 1.7 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.3 | 1.7 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 0.3 | 2.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.3 | 6.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.3 | 2.7 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.3 | 16.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.3 | 1.0 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.3 | 3.9 | GO:0071203 | WASH complex(GO:0071203) |
| 0.3 | 9.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.3 | 5.5 | GO:0000800 | lateral element(GO:0000800) |
| 0.3 | 3.5 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.3 | 5.4 | GO:0042627 | chylomicron(GO:0042627) |
| 0.3 | 2.2 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.3 | 1.2 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.3 | 3.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.3 | 61.6 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.3 | 2.6 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.3 | 3.5 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.3 | 7.6 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.3 | 5.9 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.3 | 5.2 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.3 | 3.4 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.3 | 2.6 | GO:0032009 | early phagosome(GO:0032009) |
| 0.3 | 7.1 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.2 | 6.2 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.2 | 10.2 | GO:0097546 | ciliary base(GO:0097546) |
| 0.2 | 1.7 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.2 | 2.2 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 7.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.2 | 4.3 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.2 | 3.1 | GO:0005883 | neurofilament(GO:0005883) |
| 0.2 | 2.2 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.2 | 5.8 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.2 | 3.1 | GO:0030673 | axolemma(GO:0030673) |
| 0.2 | 2.2 | GO:0005902 | microvillus(GO:0005902) |
| 0.2 | 1.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.2 | 7.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.2 | 4.6 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 26.9 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.2 | 0.6 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.2 | 1.7 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.2 | 3.3 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.2 | 0.7 | GO:0035841 | new growing cell tip(GO:0035841) |
| 0.2 | 17.8 | GO:0030175 | filopodium(GO:0030175) |
| 0.2 | 1.3 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.2 | 3.9 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.2 | 2.1 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.2 | 1.4 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.2 | 2.9 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.2 | 13.5 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.2 | 3.6 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.2 | 2.0 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.2 | 0.6 | GO:0097123 | cyclin A1-CDK2 complex(GO:0097123) |
| 0.2 | 2.9 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 1.0 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.1 | 1.8 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 0.9 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.1 | 4.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 2.0 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 12.3 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 8.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 5.5 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.1 | 21.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 6.5 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 0.4 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.1 | 0.8 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.1 | 3.3 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.1 | 9.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 6.3 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.1 | 8.2 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.1 | 4.8 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 1.0 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.1 | 0.9 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 1.1 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 1.7 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 7.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 1.5 | GO:0030914 | SAGA complex(GO:0000124) STAGA complex(GO:0030914) |
| 0.1 | 13.4 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 1.0 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 2.2 | GO:0044453 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.1 | 14.6 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 0.5 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.1 | 19.0 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 7.2 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 0.9 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 2.1 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 0.4 | GO:0060091 | kinocilium(GO:0060091) |
| 0.1 | 113.1 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 2.8 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 1.3 | GO:0031082 | BLOC complex(GO:0031082) |
| 0.1 | 2.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 6.6 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 0.4 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 3.4 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.1 | 0.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.1 | 3.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 7.5 | GO:0030426 | growth cone(GO:0030426) |
| 0.1 | 13.6 | GO:0043235 | receptor complex(GO:0043235) |
| 0.1 | 2.5 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 3.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 0.6 | GO:0000791 | euchromatin(GO:0000791) |
| 0.1 | 0.6 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 8.5 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.1 | 1.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.1 | 2.0 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 3.5 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.1 | 1.4 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 1.3 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 8.6 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 1.0 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.1 | 0.7 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 0.4 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 0.7 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.6 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 2.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.4 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.1 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.0 | 2.7 | GO:0031514 | motile cilium(GO:0031514) |
| 0.0 | 1.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 3.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 38.7 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 10.9 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 0.3 | GO:0070187 | telosome(GO:0070187) |
| 0.0 | 1.3 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.4 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.1 | GO:0031226 | intrinsic component of plasma membrane(GO:0031226) |
| 0.0 | 1.8 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 0.2 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.0 | 1.4 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.6 | 26.3 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 4.5 | 13.5 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
| 4.2 | 41.6 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 3.6 | 14.2 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 2.8 | 8.4 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) |
| 2.3 | 11.4 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 2.2 | 6.5 | GO:0004878 | complement component C5a receptor activity(GO:0004878) |
| 2.0 | 2.0 | GO:0001855 | complement component C4b binding(GO:0001855) |
| 2.0 | 5.9 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 1.9 | 7.6 | GO:0032810 | sterol response element binding(GO:0032810) |
| 1.9 | 7.5 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 1.9 | 26.1 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 1.7 | 5.2 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 1.7 | 15.4 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 1.7 | 8.3 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 1.6 | 4.7 | GO:0015389 | pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389) |
| 1.6 | 12.4 | GO:0016433 | rRNA (adenine) methyltransferase activity(GO:0016433) |
| 1.6 | 6.2 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 1.5 | 6.1 | GO:0005277 | acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375) |
| 1.5 | 10.6 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 1.5 | 4.5 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 1.4 | 4.3 | GO:0042008 | interleukin-18 receptor activity(GO:0042008) |
| 1.4 | 5.7 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 1.4 | 9.9 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 1.4 | 6.9 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 1.3 | 4.0 | GO:0004040 | amidase activity(GO:0004040) |
| 1.3 | 5.2 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 1.3 | 2.6 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
| 1.3 | 6.4 | GO:0051120 | hepoxilin A3 synthase activity(GO:0051120) |
| 1.3 | 3.8 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 1.3 | 3.8 | GO:0004584 | dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584) |
| 1.3 | 10.2 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 1.3 | 6.4 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 1.2 | 13.7 | GO:0008061 | chitinase activity(GO:0004568) chitin binding(GO:0008061) |
| 1.2 | 5.9 | GO:0050436 | microfibril binding(GO:0050436) |
| 1.1 | 6.9 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 1.1 | 4.6 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 1.1 | 6.7 | GO:0030172 | troponin C binding(GO:0030172) |
| 1.1 | 21.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 1.1 | 3.4 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 1.1 | 3.3 | GO:0004144 | diacylglycerol O-acyltransferase activity(GO:0004144) |
| 1.1 | 4.4 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 1.1 | 7.6 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 1.1 | 3.2 | GO:0036134 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 1.1 | 4.2 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 1.1 | 5.3 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 1.0 | 4.1 | GO:0004979 | beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047) |
| 1.0 | 3.0 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
| 1.0 | 14.9 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 1.0 | 15.8 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 1.0 | 3.9 | GO:0016495 | C-X3-C chemokine receptor activity(GO:0016495) |
| 1.0 | 4.9 | GO:0003796 | lysozyme activity(GO:0003796) |
| 1.0 | 11.5 | GO:0008430 | selenium binding(GO:0008430) |
| 1.0 | 3.8 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 1.0 | 3.8 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.9 | 2.8 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 0.9 | 2.8 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 0.9 | 4.7 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.9 | 4.6 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.9 | 6.5 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.9 | 8.2 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.9 | 2.7 | GO:0048030 | disaccharide binding(GO:0048030) |
| 0.9 | 2.7 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.9 | 5.3 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.9 | 1.7 | GO:0016890 | site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890) |
| 0.9 | 6.0 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 0.9 | 2.6 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
| 0.8 | 4.2 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 0.8 | 4.2 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.8 | 2.5 | GO:0070119 | ciliary neurotrophic factor binding(GO:0070119) |
| 0.8 | 7.4 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.8 | 18.1 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
| 0.8 | 3.3 | GO:0005497 | androgen binding(GO:0005497) |
| 0.8 | 8.1 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.8 | 2.4 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.8 | 4.1 | GO:1901474 | azole transmembrane transporter activity(GO:1901474) |
| 0.8 | 4.9 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.8 | 3.1 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.8 | 2.4 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.8 | 19.4 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.8 | 3.1 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.8 | 3.8 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.8 | 3.8 | GO:0008410 | CoA-transferase activity(GO:0008410) |
| 0.8 | 6.8 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.8 | 4.5 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.7 | 6.0 | GO:0015185 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 0.7 | 14.8 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.7 | 3.0 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 0.7 | 2.2 | GO:0061609 | fructose-1-phosphate aldolase activity(GO:0061609) |
| 0.7 | 5.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.7 | 2.1 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.7 | 4.9 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.7 | 9.8 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.7 | 4.2 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.7 | 6.2 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.7 | 2.1 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.7 | 4.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.7 | 3.4 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 0.7 | 10.8 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.7 | 2.0 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 0.7 | 3.3 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.7 | 3.3 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.7 | 3.9 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.6 | 2.5 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.6 | 6.9 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.6 | 8.7 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.6 | 4.9 | GO:0031812 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.6 | 1.2 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.6 | 1.8 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.6 | 3.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.6 | 2.4 | GO:0004146 | dihydrofolate reductase activity(GO:0004146) |
| 0.6 | 10.8 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.6 | 3.6 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.6 | 2.4 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.6 | 10.7 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.6 | 10.1 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.6 | 1.8 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.6 | 2.9 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 0.6 | 1.7 | GO:0003826 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 0.6 | 1.7 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.6 | 2.9 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.6 | 2.3 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
| 0.6 | 2.3 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.6 | 5.6 | GO:0043199 | sulfate binding(GO:0043199) |
| 0.6 | 9.4 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.6 | 4.4 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.5 | 2.7 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.5 | 2.2 | GO:0004802 | transketolase activity(GO:0004802) |
| 0.5 | 3.8 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.5 | 3.2 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.5 | 2.1 | GO:0032406 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 0.5 | 4.7 | GO:0030883 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
| 0.5 | 6.2 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.5 | 1.5 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.5 | 2.1 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
| 0.5 | 6.6 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.5 | 3.5 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.5 | 13.5 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.5 | 4.0 | GO:0019863 | IgE binding(GO:0019863) |
| 0.5 | 2.5 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.5 | 16.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.5 | 4.8 | GO:0015386 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.5 | 9.7 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.5 | 1.4 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.5 | 8.8 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.5 | 6.9 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.5 | 2.3 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.5 | 4.6 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 0.5 | 2.7 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.4 | 1.3 | GO:0003865 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 0.4 | 3.1 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.4 | 1.8 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 0.4 | 5.8 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.4 | 21.0 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.4 | 23.8 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.4 | 3.0 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988) |
| 0.4 | 1.3 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
| 0.4 | 1.3 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.4 | 2.1 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.4 | 5.1 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.4 | 3.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.4 | 1.2 | GO:0004961 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 0.4 | 1.6 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
| 0.4 | 7.7 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.4 | 2.4 | GO:0004630 | phospholipase D activity(GO:0004630) |
| 0.4 | 4.8 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.4 | 3.5 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.4 | 1.9 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.4 | 3.1 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.4 | 20.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.4 | 1.9 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.4 | 1.1 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.4 | 6.1 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
| 0.4 | 3.8 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.4 | 2.6 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.4 | 1.9 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
| 0.4 | 7.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.4 | 3.7 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.4 | 2.2 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.4 | 0.7 | GO:0050051 | leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 0.4 | 2.1 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.4 | 13.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.3 | 2.1 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.3 | 15.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.3 | 4.1 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.3 | 91.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.3 | 1.7 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.3 | 2.0 | GO:0005230 | extracellular ligand-gated ion channel activity(GO:0005230) |
| 0.3 | 3.0 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.3 | 5.3 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.3 | 9.8 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.3 | 18.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.3 | 12.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.3 | 2.6 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
| 0.3 | 6.7 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.3 | 6.1 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.3 | 6.7 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.3 | 6.7 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.3 | 0.9 | GO:0070984 | SET domain binding(GO:0070984) |
| 0.3 | 1.2 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.3 | 6.5 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.3 | 2.2 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.3 | 1.8 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.3 | 8.3 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.3 | 7.7 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.3 | 9.1 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.3 | 6.7 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.3 | 12.4 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.3 | 1.2 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.3 | 16.9 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.3 | 2.7 | GO:0019158 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.3 | 3.0 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.3 | 8.2 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.3 | 0.9 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.3 | 1.4 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.3 | 4.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.3 | 11.2 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.3 | 2.0 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 0.3 | 2.2 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
| 0.3 | 4.7 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.3 | 7.7 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.3 | 8.0 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.3 | 15.9 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.3 | 0.8 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.3 | 1.9 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.3 | 6.4 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.3 | 6.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.3 | 4.7 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.3 | 2.1 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.3 | 0.8 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.3 | 5.3 | GO:0099589 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589) |
| 0.3 | 1.8 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.2 | 8.2 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.2 | 1.5 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.2 | 2.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.2 | 3.7 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.2 | 9.5 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.2 | 3.8 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.2 | 3.5 | GO:0017136 | NAD-dependent histone deacetylase activity(GO:0017136) |
| 0.2 | 1.4 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.2 | 5.4 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.2 | 1.2 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.2 | 3.5 | GO:0015250 | water channel activity(GO:0015250) |
| 0.2 | 1.6 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.2 | 3.2 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.2 | 1.8 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.2 | 1.6 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.2 | 2.4 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.2 | 1.1 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.2 | 6.1 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.2 | 2.2 | GO:0005549 | odorant binding(GO:0005549) |
| 0.2 | 0.9 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.2 | 3.0 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.2 | 1.9 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.2 | 1.3 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 2.7 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.2 | 1.9 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.2 | 3.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.2 | 1.2 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.2 | 2.8 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.2 | 2.6 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
| 0.2 | 3.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.2 | 0.6 | GO:0030305 | beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305) |
| 0.2 | 1.5 | GO:0016713 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 0.2 | 1.1 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.2 | 3.0 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 1.5 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.2 | 0.6 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.2 | 13.1 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.2 | 0.5 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711) |
| 0.2 | 0.7 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.2 | 6.8 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.2 | 4.2 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.2 | 19.6 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.2 | 1.0 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.2 | 58.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.2 | 0.5 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.2 | 3.1 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.2 | 2.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.2 | 1.0 | GO:1901682 | sulfur compound transmembrane transporter activity(GO:1901682) |
| 0.2 | 14.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.2 | 1.0 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.2 | 1.0 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.2 | 3.8 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.2 | 2.7 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.2 | 2.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.2 | 12.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.2 | 8.1 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.2 | 0.9 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.2 | 2.9 | GO:0031005 | filamin binding(GO:0031005) |
| 0.2 | 0.5 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 0.1 | 1.9 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.1 | 1.8 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.1 | 8.8 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.1 | 0.4 | GO:0032181 | double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181) |
| 0.1 | 0.9 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.1 | 4.2 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 1.7 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 4.1 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 1.3 | GO:0050664 | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664) |
| 0.1 | 2.2 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 12.4 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 10.0 | GO:0001099 | basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099) |
| 0.1 | 2.2 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.1 | 13.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 1.0 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.1 | 7.3 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 1.2 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.1 | 1.5 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 1.0 | GO:0030345 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.1 | 1.3 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.1 | 0.6 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 0.4 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 0.1 | 5.1 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 2.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.1 | 1.1 | GO:0003720 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.1 | 3.6 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.1 | 0.5 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.1 | 1.5 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.1 | 0.5 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 2.3 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.1 | 0.5 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.1 | 4.4 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 2.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 0.6 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.1 | 1.3 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.1 | 1.4 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.1 | 1.7 | GO:0019825 | oxygen binding(GO:0019825) |
| 0.1 | 0.4 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.1 | 0.5 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 1.8 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.1 | 1.1 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.1 | 110.2 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.1 | 2.5 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 0.8 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.1 | 2.2 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 1.1 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.1 | 0.3 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.1 | 0.9 | GO:0019864 | IgG binding(GO:0019864) |
| 0.1 | 1.0 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 1.0 | GO:0010181 | FMN binding(GO:0010181) |
| 0.1 | 2.5 | GO:0008408 | 3'-5' exonuclease activity(GO:0008408) |
| 0.1 | 0.3 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 0.1 | 1.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 1.7 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 1.6 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 0.5 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.1 | 0.7 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.1 | 1.5 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 0.5 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.1 | 1.8 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.1 | 1.9 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 1.3 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 2.7 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 2.8 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 1.0 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 1.5 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.5 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 0.3 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.0 | 0.7 | GO:0016849 | phosphorus-oxygen lyase activity(GO:0016849) |
| 0.0 | 1.6 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 2.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.2 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
| 0.0 | 0.3 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.0 | 0.7 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.3 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.4 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 0.4 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.8 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 0.4 | GO:0001637 | G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) |
| 0.0 | 0.2 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
| 0.0 | 0.2 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.0 | 0.4 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 0.2 | GO:0015065 | uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553) |
| 0.0 | 0.1 | GO:0004102 | choline O-acetyltransferase activity(GO:0004102) |
| 0.0 | 1.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 2.0 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
| 0.0 | 0.3 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.0 | 1.5 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 11.2 | GO:0004888 | transmembrane signaling receptor activity(GO:0004888) |
| 0.0 | 0.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.2 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.0 | 0.1 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.0 | 0.7 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
| 0.0 | 0.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 57.1 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.9 | 30.5 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.7 | 13.7 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.6 | 36.3 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.6 | 4.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.5 | 6.8 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.5 | 4.2 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.4 | 2.2 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.4 | 1.7 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.4 | 15.1 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.4 | 7.0 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.4 | 16.9 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.4 | 12.0 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.4 | 2.5 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.4 | 13.8 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.3 | 6.4 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.3 | 7.1 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.3 | 14.3 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.3 | 9.0 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.3 | 19.2 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.3 | 24.7 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.3 | 14.3 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.3 | 23.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.3 | 10.4 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.3 | 12.0 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.3 | 8.3 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.2 | 5.5 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.2 | 5.8 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.2 | 4.8 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.2 | 1.9 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.2 | 1.4 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.2 | 2.1 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 6.6 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.2 | 2.3 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.2 | 1.4 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.2 | 3.8 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.2 | 2.6 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.2 | 2.2 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.2 | 6.5 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.2 | 5.6 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.2 | 4.9 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.2 | 3.1 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.2 | 27.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.2 | 7.5 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.2 | 17.1 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.2 | 2.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.2 | 7.0 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.1 | 4.0 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.1 | 1.6 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.1 | 7.7 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 4.2 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.1 | 2.2 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 7.0 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 3.6 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 4.2 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 10.5 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 5.2 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 3.8 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.1 | 4.6 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 3.6 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 1.7 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 2.6 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 1.8 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.1 | 2.8 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.1 | 4.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 6.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 1.6 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 1.5 | PID MYC PATHWAY | C-MYC pathway |
| 0.1 | 3.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.5 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 0.6 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 12.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 10.1 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 0.5 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 1.0 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.5 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 0.2 | ST GAQ PATHWAY | G alpha q Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 14.6 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.7 | 15.7 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.7 | 30.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.6 | 4.3 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.6 | 82.4 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.6 | 11.6 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.6 | 0.6 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.6 | 9.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.5 | 12.5 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
| 0.5 | 7.8 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.5 | 15.2 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.5 | 18.6 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.5 | 4.9 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.5 | 15.5 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.5 | 5.9 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.5 | 10.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.4 | 6.2 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.4 | 7.9 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.4 | 27.3 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.4 | 42.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.4 | 17.1 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.4 | 12.5 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.4 | 10.9 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.4 | 4.8 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.4 | 9.9 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.4 | 2.6 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.4 | 6.5 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.4 | 9.0 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.4 | 6.5 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.4 | 4.7 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.4 | 18.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.3 | 19.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.3 | 4.0 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.3 | 4.2 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.3 | 12.1 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.3 | 24.5 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.3 | 5.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.3 | 4.2 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.3 | 2.7 | REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT | Genes involved in Lipid digestion, mobilization, and transport |
| 0.3 | 7.3 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.3 | 2.5 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.3 | 11.0 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.3 | 1.6 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.3 | 5.2 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.3 | 11.3 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.2 | 5.6 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.2 | 1.4 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.2 | 4.9 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.2 | 3.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.2 | 3.2 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.2 | 28.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.2 | 13.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.2 | 29.7 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.2 | 8.2 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.2 | 74.3 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.2 | 19.4 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.2 | 4.1 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.2 | 1.9 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.2 | 4.7 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.2 | 4.0 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.2 | 2.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.2 | 3.7 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.2 | 9.2 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.2 | 5.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.2 | 3.0 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.2 | 12.5 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.2 | 0.7 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.2 | 3.5 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.2 | 3.5 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.2 | 7.2 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.2 | 1.8 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.2 | 3.2 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.1 | 4.1 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 3.4 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 8.6 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 4.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 3.1 | REACTOME BOTULINUM NEUROTOXICITY | Genes involved in Botulinum neurotoxicity |
| 0.1 | 1.4 | REACTOME OPSINS | Genes involved in Opsins |
| 0.1 | 3.2 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 3.0 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.1 | 2.3 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 1.7 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.1 | 1.4 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 0.6 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.1 | 6.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 1.1 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.1 | 3.2 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.1 | 3.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 3.1 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.1 | 0.8 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 0.6 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.1 | 0.6 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.1 | 3.4 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 0.7 | REACTOME DEFENSINS | Genes involved in Defensins |
| 0.1 | 2.3 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 0.5 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.1 | 3.4 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 2.4 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 1.5 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 0.6 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 0.1 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.1 | 1.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 2.0 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 0.4 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.1 | 1.0 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 3.1 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.0 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 0.3 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 2.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.4 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.0 | 0.1 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.4 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.4 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |