avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
TBX19 Links Ensembl NCBI GeneCards UniProt	ENSG00000143178.13	TBX19

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TBX19	hg38_v1_chr1_+_168280872_168280882	-0.13	5.4e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr14_-_106185387 Show fit	20.99	ENST00000390605.2	IGHV1-18 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-18
chrX_+_120604084 Show fit	19.75	ENST00000371317.10	MCTS1 Links Ensembl NCBI GeneCards UniProt Show fit	MCTS1 re-initiation and release factor
chr16_+_84768246 Show fit	18.96	ENST00000569925.1 ENST00000567526.1	USP10 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 10
chr6_-_36547400 Show fit	18.74	ENST00000229812.8	STK38 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 38
chr9_-_113410666 Show fit	18.65	ENST00000374171.5	POLE3 Links Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase epsilon 3, accessory subunit
chr10_-_119536533 Show fit	18.45	ENST00000392865.5	RGS10 Links Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 10
chrX_+_120604199 Show fit	16.03	ENST00000371315.3	MCTS1 Links Ensembl NCBI GeneCards UniProt Show fit	MCTS1 re-initiation and release factor
chr15_+_41286011 Show fit	15.76	ENST00000661438.1	ENSG00000285920.2 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr2_-_85409805 Show fit	15.18	ENST00000449030.5	CAPG Links Ensembl NCBI GeneCards UniProt Show fit	capping actin protein, gelsolin like
chr10_-_93482326 Show fit	15.03	ENST00000359263.9	MYOF Links Ensembl NCBI GeneCards UniProt Show fit	myoferlin
chr10_-_93482194 Show fit	14.59	ENST00000358334.9 ENST00000371488.3	MYOF Links Ensembl NCBI GeneCards UniProt Show fit	myoferlin
chr7_-_133082032 Show fit	14.50	ENST00000448878.6 ENST00000262570.10	CHCHD3 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_-_2841853 Show fit	14.10	ENST00000380739.6	SERPINB1 Links Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 1
chr7_-_148883474 Show fit	13.86	ENST00000476773.5	EZH2 Links Ensembl NCBI GeneCards UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr12_-_48925483 Show fit	13.37	ENST00000550765.6 ENST00000552878.5 ENST00000453172.2	FKBP11 Links Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 11
chr1_+_32292067 Show fit	13.27	ENST00000373548.8 ENST00000428704.1	HDAC1 Links Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 1
chr7_+_2354810 Show fit	12.84	ENST00000360876.9 ENST00000413917.5 ENST00000397011.2	EIF3B Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit B
chr12_+_52069967 Show fit	12.60	ENST00000336854.9 ENST00000550604.1 ENST00000553049.5 ENST00000548915.1	ATG101 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 101
chr13_+_50909905 Show fit	12.20	ENST00000644034.1 ENST00000645955.1	RNASEH2B Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease H2 subunit B
chr14_-_106507476 Show fit	12.15	ENST00000390621.3	IGHV1-45 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-45
chr1_-_160647287 Show fit	12.13	ENST00000235739.6	SLAMF1 Links Ensembl NCBI GeneCards UniProt Show fit	signaling lymphocytic activation molecule family member 1
chr8_-_63038788 Show fit	11.87	ENST00000518113.2 ENST00000260118.7 ENST00000677482.1	GGH Links Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyl hydrolase
chr10_-_119178791 Show fit	11.72	ENST00000298510.4	PRDX3 Links Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin 3
chr15_-_55289756 Show fit	11.45	ENST00000336787.6	RAB27A Links Ensembl NCBI GeneCards UniProt Show fit	RAB27A, member RAS oncogene family
chr11_+_72227881 Show fit	10.97	ENST00000538751.5 ENST00000541756.5	INPPL1 Links Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate phosphatase like 1
chr1_+_158930778 Show fit	10.73	ENST00000458222.5	PYHIN1 Links Ensembl NCBI GeneCards UniProt Show fit	pyrin and HIN domain family member 1
chr1_-_63523175 Show fit	10.71	ENST00000371092.7 ENST00000271002.15	ITGB3BP Links Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 3 binding protein
chr14_+_20781139 Show fit	10.58	ENST00000304677.3	RNASE6 Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member k6
chr2_+_90114838 Show fit	10.55	ENST00000417279.3	IGKV3D-15 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-15
chr1_+_171512032 Show fit	10.09	ENST00000426496.6	PRRC2C Links Ensembl NCBI GeneCards UniProt Show fit	proline rich coiled-coil 2C
chr2_+_200889327 Show fit	9.76	ENST00000426253.5 ENST00000454952.1 ENST00000651500.1 ENST00000409020.6 ENST00000359683.8	NIF3L1 Links Ensembl NCBI GeneCards UniProt Show fit	NGG1 interacting factor 3 like 1
chr5_+_96876480 Show fit	9.60	ENST00000437043.8 ENST00000379904.8	ERAP2 Links Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum aminopeptidase 2
chr5_+_33440696 Show fit	9.46	ENST00000502553.5 ENST00000514259.5	TARS1 Links Ensembl NCBI GeneCards UniProt Show fit	threonyl-tRNA synthetase 1
chr6_+_22569554 Show fit	9.38	ENST00000510882.4	HDGFL1 Links Ensembl NCBI GeneCards UniProt Show fit	HDGF like 1
chr1_-_150697128 Show fit	9.31	ENST00000427665.1 ENST00000271732.8	GOLPH3L Links Ensembl NCBI GeneCards UniProt Show fit	golgi phosphoprotein 3 like
chr1_-_193105373 Show fit	8.76	ENST00000367439.8	GLRX2 Links Ensembl NCBI GeneCards UniProt Show fit	glutaredoxin 2
chr14_+_23988884 Show fit	8.71	ENST00000558753.5 ENST00000537912.5	DHRS4L2 Links Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase 4 like 2
chr2_+_200889411 Show fit	8.69	ENST00000409357.5 ENST00000409129.2	NIF3L1 Links Ensembl NCBI GeneCards UniProt Show fit	NGG1 interacting factor 3 like 1
chr2_-_89027700 Show fit	8.59	ENST00000483158.1	IGKV3-11 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-11
chr10_+_75210151 Show fit	8.50	ENST00000298468.9 ENST00000543351.5	VDAC2 Links Ensembl NCBI GeneCards UniProt Show fit	voltage dependent anion channel 2
chr1_-_160647037 Show fit	8.38	ENST00000302035.11	SLAMF1 Links Ensembl NCBI GeneCards UniProt Show fit	signaling lymphocytic activation molecule family member 1
chr1_+_207454230 Show fit	8.28	ENST00000367058.7 ENST00000367059.3 ENST00000367057.8	CR2 Links Ensembl NCBI GeneCards UniProt Show fit	complement C3d receptor 2
chr2_-_27323006 Show fit	7.87	ENST00000402310.5 ENST00000405983.5 ENST00000403262.6	MPV17 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial inner membrane protein MPV17
chr22_+_44677044 Show fit	7.79	ENST00000006251.11	PRR5 Links Ensembl NCBI GeneCards UniProt Show fit	proline rich 5
chr7_-_141014939 Show fit	7.54	ENST00000324787.10 ENST00000467334.1	MRPS33 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S33
chr2_+_89851723 Show fit	7.35	ENST00000429992.2	IGKV2D-40 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-40
chr19_+_48993525 Show fit	7.05	ENST00000601968.5 ENST00000596837.5	RUVBL2 Links Ensembl NCBI GeneCards UniProt Show fit	RuvB like AAA ATPase 2
chr6_+_52420107 Show fit	6.99	ENST00000636489.1 ENST00000637089.1 ENST00000637353.1 ENST00000637263.1	EFHC1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain containing 1
chr17_-_64505357 Show fit	6.97	ENST00000583212.2 ENST00000578190.5 ENST00000579091.5 ENST00000583239.6	DDX5 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 5
chr5_+_36166556 Show fit	6.81	ENST00000677886.1	SKP2 Links Ensembl NCBI GeneCards UniProt Show fit	S-phase kinase associated protein 2
chr22_+_44677077 Show fit	6.61	ENST00000403581.5	PRR5 Links Ensembl NCBI GeneCards UniProt Show fit	proline rich 5
chr5_+_35856883 Show fit	6.46	ENST00000506850.5 ENST00000303115.8 ENST00000511982.1	IL7R Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 7 receptor
chr10_+_17644126 Show fit	6.40	ENST00000377524.8	STAM Links Ensembl NCBI GeneCards UniProt Show fit	signal transducing adaptor molecule
chr2_+_3575250 Show fit	6.14	ENST00000645674.2	RPS7 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S7
chr19_-_38847423 Show fit	6.08	ENST00000647557.1	HNRNPL Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein L
chr20_+_3209469 Show fit	5.98	ENST00000380113.8 ENST00000455664.6 ENST00000399838.3	ITPA Links Ensembl NCBI GeneCards UniProt Show fit	inosine triphosphatase
chr2_-_88979016 Show fit	5.88	ENST00000390247.2	IGKV3-7 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-7 (non-functional)
chr6_+_10694916 Show fit	5.72	ENST00000379568.4	PAK1IP1 Links Ensembl NCBI GeneCards UniProt Show fit	PAK1 interacting protein 1
chr9_-_128127711 Show fit	5.70	ENST00000449878.1 ENST00000338961.11 ENST00000678174.1	PTGES2 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E synthase 2
chr2_+_90234809 Show fit	5.64	ENST00000443397.5	IGKV3D-7 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-7
chr1_-_167935987 Show fit	5.56	ENST00000367846.8	MPC2 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial pyruvate carrier 2
chr1_-_150974867 Show fit	5.52	ENST00000271688.10	CERS2 Links Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 2
chr2_+_143129379 Show fit	5.48	ENST00000295095.11	ARHGAP15 Links Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 15
chr6_+_52420332 Show fit	5.46	ENST00000636107.1 ENST00000371068.11 ENST00000636702.1 ENST00000635996.1 ENST00000636379.1	EFHC1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain containing 1
chr6_-_42746054 Show fit	5.28	ENST00000372876.2	TBCC Links Ensembl NCBI GeneCards UniProt Show fit	tubulin folding cofactor C
chr14_-_106154113 Show fit	5.18	ENST00000390603.2	IGHV3-15 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-15
chr19_-_7702124 Show fit	4.78	ENST00000597921.6	FCER2 Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgE receptor II
chrX_-_120575783 Show fit	4.73	ENST00000680673.1	CUL4B Links Ensembl NCBI GeneCards UniProt Show fit	cullin 4B
chr17_+_7219857 Show fit	4.66	ENST00000583312.5 ENST00000350303.9 ENST00000584103.5 ENST00000356839.10 ENST00000579886.2	ACADVL Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA dehydrogenase very long chain
chr7_-_76626127 Show fit	4.59	ENST00000454397.1	POMZP3 Links Ensembl NCBI GeneCards UniProt Show fit	POM121 and ZP3 fusion
chr20_-_5113032 Show fit	4.59	ENST00000379299.6 ENST00000379286.6 ENST00000379279.6 ENST00000379283.6	TMEM230 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 230
chr17_+_36948925 Show fit	4.53	ENST00000616434.2 ENST00000680340.1 ENST00000619387.5 ENST00000679997.1	AATF Links Ensembl NCBI GeneCards UniProt Show fit	apoptosis antagonizing transcription factor
chr12_-_9607903 Show fit	4.35	ENST00000229402.4	KLRB1 Links Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor B1
chr19_-_7702139 Show fit	4.28	ENST00000346664.9	FCER2 Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgE receptor II
chr11_+_57657736 Show fit	4.27	ENST00000529773.2 ENST00000533905.1 ENST00000525602.1 ENST00000533682.2 ENST00000302731.4	CLP1 Links Ensembl NCBI GeneCards UniProt Show fit	cleavage factor polyribonucleotide kinase subunit 1
chr17_-_78874038 Show fit	4.12	ENST00000586057.5	TIMP2 Links Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 2
chr20_-_5113067 Show fit	4.09	ENST00000342308.10 ENST00000612323.4 ENST00000202834.11	TMEM230 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 230
chr1_+_168280872 Show fit	4.06	ENST00000367821.8	TBX19 Links Ensembl NCBI GeneCards UniProt Show fit	T-box transcription factor 19
chr10_+_5094405 Show fit	3.99	ENST00000380554.5	AKR1C3 Links Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1 member C3
chr20_-_46363174 Show fit	3.99	ENST00000372227.5	SLC35C2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 member C2
chr18_+_62539511 Show fit	3.97	ENST00000586834.1	ZCCHC2 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCHC-type containing 2
chr1_-_167553745 Show fit	3.90	ENST00000370509.5	CREG1 Links Ensembl NCBI GeneCards UniProt Show fit	cellular repressor of E1A stimulated genes 1
chr15_-_60479080 Show fit	3.88	ENST00000560072.5 ENST00000560406.5 ENST00000560520.1 ENST00000261520.9	ICE2 Links Ensembl NCBI GeneCards UniProt Show fit	interactor of little elongation complex ELL subunit 2
chr5_+_169583636 Show fit	3.77	ENST00000506574.5 ENST00000515224.5 ENST00000629457.2 ENST00000508247.5 ENST00000265295.9 ENST00000513941.5	SPDL1 Links Ensembl NCBI GeneCards UniProt Show fit	spindle apparatus coiled-coil protein 1
chr1_+_116754422 Show fit	3.71	ENST00000369478.4 ENST00000369477.1	CD2 Links Ensembl NCBI GeneCards UniProt Show fit	CD2 molecule
chr22_+_35257452 Show fit	3.69	ENST00000420166.5 ENST00000216106.6 ENST00000455359.5	HMGXB4 Links Ensembl NCBI GeneCards UniProt Show fit	HMG-box containing 4
chr3_-_194672175 Show fit	3.60	ENST00000265245.10	LSG1 Links Ensembl NCBI GeneCards UniProt Show fit	large 60S subunit nuclear export GTPase 1
chr14_-_106875069 Show fit	3.60	ENST00000390639.2	IGHV7-81 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 7-81 (non-functional)
chr12_+_8123609 Show fit	3.52	ENST00000229332.12	CLEC4A Links Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 4 member A
chr2_-_9423340 Show fit	3.44	ENST00000484735.5 ENST00000456913.6	ITGB1BP1 Links Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 1 binding protein 1
chr1_+_113929304 Show fit	3.37	ENST00000426820.7	HIPK1 Links Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 1
chr19_-_7943648 Show fit	3.33	ENST00000597926.1 ENST00000270538.8	TIMM44 Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 44
chr1_+_113929350 Show fit	3.23	ENST00000369559.8 ENST00000626993.2	HIPK1 Links Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 1
chr14_-_106511856 Show fit	3.12	ENST00000390622.2	IGHV1-46 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-46
chr6_+_30617825 Show fit	3.12	ENST00000259873.5	MRPS18B Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S18B
chr17_-_19745369 Show fit	3.10	ENST00000573368.5 ENST00000457500.6	ALDH3A1 Links Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 3 family member A1
chr2_-_112836702 Show fit	3.07	ENST00000416750.1 ENST00000263341.7 ENST00000418817.5	IL1B Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 beta
chr1_+_113929600 Show fit	3.04	ENST00000369558.5 ENST00000369561.8	HIPK1 Links Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 1
chr9_-_128128102 Show fit	2.86	ENST00000617202.4	PTGES2 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E synthase 2
chr6_-_31684040 Show fit	2.83	ENST00000375863.7	LY6G5C Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 6 family member G5C
chr11_-_65121780 Show fit	2.70	ENST00000525297.5 ENST00000529259.1	FAU Links Ensembl NCBI GeneCards UniProt Show fit	FAU ubiquitin like and ribosomal protein S30 fusion
chr1_+_153990749 Show fit	2.62	ENST00000651669.1	RPS27 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S27
chr13_+_102656933 Show fit	2.57	ENST00000650757.1	TPP2 Links Ensembl NCBI GeneCards UniProt Show fit	tripeptidyl peptidase 2
chr8_+_32548210 Show fit	2.56	ENST00000523079.5 ENST00000650919.1	NRG1 Links Ensembl NCBI GeneCards UniProt Show fit	neuregulin 1
chr19_+_4247074 Show fit	2.40	ENST00000262962.12	YJU2 Links Ensembl NCBI GeneCards UniProt Show fit	YJU2 splicing factor homolog
chr6_+_85449584 Show fit	2.36	ENST00000369651.7	NT5E Links Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase ecto
chr12_+_8123837 Show fit	2.32	ENST00000345999.9 ENST00000352620.9 ENST00000360500.5	CLEC4A Links Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 4 member A
chrX_+_108045050 Show fit	2.25	ENST00000458383.1 ENST00000217957.10	VSIG1 Links Ensembl NCBI GeneCards UniProt Show fit	V-set and immunoglobulin domain containing 1
chr1_+_100345018 Show fit	2.24	ENST00000635056.2 ENST00000647005.1	CDC14A Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14A
chr1_+_40691689 Show fit	2.23	ENST00000427410.6 ENST00000447388.7 ENST00000425457.6 ENST00000453631.5 ENST00000456393.6	NFYC Links Ensembl NCBI GeneCards UniProt Show fit	nuclear transcription factor Y subunit gamma
chr9_+_75890664 Show fit	2.20	ENST00000376767.7 ENST00000674117.1 ENST00000376752.8	PCSK5 Links Ensembl NCBI GeneCards UniProt Show fit	proprotein convertase subtilisin/kexin type 5
chr14_-_106360320 Show fit	2.19	ENST00000390615.2	IGHV3-33 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-33
chr10_-_11532275 Show fit	2.15	ENST00000277575.5	USP6NL Links Ensembl NCBI GeneCards UniProt Show fit	USP6 N-terminal like
chr2_-_33599269 Show fit	2.13	ENST00000431950.1 ENST00000403368.1 ENST00000238823.13	FAM98A Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 98 member A
chr7_+_93906557 Show fit	2.09	ENST00000248572.10 ENST00000429473.1 ENST00000430875.1 ENST00000428834.1	GNGT1 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit gamma transducin 1
chr22_+_31081310 Show fit	2.06	ENST00000426927.5 ENST00000482444.5 ENST00000440425.5 ENST00000333137.12 ENST00000358743.5 ENST00000347557.6	SMTN Links Ensembl NCBI GeneCards UniProt Show fit	smoothelin
chr4_+_69096494 Show fit	2.02	ENST00000508661.5 ENST00000622664.1	UGT2B7 Links Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B7
chr15_-_65517244 Show fit	1.97	ENST00000341861.9	DPP8 Links Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl peptidase 8
chr20_-_7940444 Show fit	1.97	ENST00000378789.4	HAO1 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxyacid oxidase 1
chr12_+_112906777 Show fit	1.93	ENST00000452357.7 ENST00000445409.7	OAS1 Links Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 1
chrX_+_130401962 Show fit	1.91	ENST00000305536.11 ENST00000370947.1	RBMX2 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein X-linked 2
chr12_-_10810168 Show fit	1.83	ENST00000240691.4	TAS2R9 Links Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 9
chr12_-_10884244 Show fit	1.82	ENST00000543626.4	PRH1 Links Ensembl NCBI GeneCards UniProt Show fit	proline rich protein HaeIII subfamily 1
chr12_+_75391078 Show fit	1.82	ENST00000550916.6 ENST00000378692.7 ENST00000320460.8 ENST00000547164.1	GLIPR1L2 Links Ensembl NCBI GeneCards UniProt Show fit	GLIPR1 like 2
chr5_-_150700910 Show fit	1.81	ENST00000521464.1 ENST00000518917.5 ENST00000447771.6 ENST00000199814.9	RBM22 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 22
chrX_+_12906639 Show fit	1.77	ENST00000311912.5	TLR8 Links Ensembl NCBI GeneCards UniProt Show fit	toll like receptor 8
chr4_+_69096467 Show fit	1.70	ENST00000305231.12	UGT2B7 Links Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B7
chrX_+_108044967 Show fit	1.69	ENST00000415430.7	VSIG1 Links Ensembl NCBI GeneCards UniProt Show fit	V-set and immunoglobulin domain containing 1
chr4_+_15703057 Show fit	1.64	ENST00000265016.9 ENST00000382346.7	BST1 Links Ensembl NCBI GeneCards UniProt Show fit	bone marrow stromal cell antigen 1
chr6_-_130956371 Show fit	1.59	ENST00000639623.1 ENST00000525193.5 ENST00000527659.5	EPB41L2 Links Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr9_+_75890639 Show fit	1.56	ENST00000545128.5	PCSK5 Links Ensembl NCBI GeneCards UniProt Show fit	proprotein convertase subtilisin/kexin type 5
chr15_+_67125707 Show fit	1.51	ENST00000540846.6	SMAD3 Links Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 3
chr6_-_26285526 Show fit	1.50	ENST00000377727.2	H4C8 Links Ensembl NCBI GeneCards UniProt Show fit	H4 clustered histone 8
chr19_+_9247344 Show fit	1.35	ENST00000641946.1	OR7E24 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 7 subfamily E member 24
chr11_-_22625804 Show fit	1.34	ENST00000327470.6	FANCF Links Ensembl NCBI GeneCards UniProt Show fit	FA complementation group F
chr21_+_38256698 Show fit	1.28	ENST00000613499.4 ENST00000612702.4 ENST00000398925.5 ENST00000398928.5 ENST00000328656.8 ENST00000443341.5	KCNJ15 Links Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 15
chr14_+_23988914 Show fit	1.27	ENST00000335125.11	DHRS4L2 Links Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase 4 like 2
chr19_+_49487510 Show fit	1.26	ENST00000679106.1 ENST00000621674.4 ENST00000391857.9 ENST00000678510.1 ENST00000467825.2	RPL13A Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L13a
chr19_+_852295 Show fit	1.16	ENST00000263621.2	ELANE Links Ensembl NCBI GeneCards UniProt Show fit	elastase, neutrophil expressed
chr1_+_78620432 Show fit	1.16	ENST00000370751.10 ENST00000459784.6 ENST00000680110.1 ENST00000680295.1	IFI44L Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein 44 like
chr2_-_213151590 Show fit	1.09	ENST00000374319.8 ENST00000457361.5 ENST00000451136.6 ENST00000434687.6	IKZF2 Links Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 2
chr5_+_55024250 Show fit	1.09	ENST00000231009.3	GZMK Links Ensembl NCBI GeneCards UniProt Show fit	granzyme K
chr1_+_160796157 Show fit	1.04	ENST00000263285.11 ENST00000368039.2	LY9 Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 9
chr5_-_33984681 Show fit	1.01	ENST00000296589.9	SLC45A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 45 member 2
chr5_-_78985288 Show fit	1.00	ENST00000264914.10	ARSB Links Ensembl NCBI GeneCards UniProt Show fit	arylsulfatase B
chr15_-_68229658 Show fit	1.00	ENST00000565471.6 ENST00000637494.1 ENST00000636314.1 ENST00000637667.1 ENST00000564752.1 ENST00000566347.5 ENST00000249806.11 ENST00000562767.2	CLN6 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000260007.3 Links Ensembl NCBI GeneCards UniProt Show fit	CLN6 transmembrane ER protein novel protein
chr6_-_26216673 Show fit	0.97	ENST00000541790.3	H2BC8 Links Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 8
chr5_-_100903252 Show fit	0.90	ENST00000231461.10	ST8SIA4 Links Ensembl NCBI GeneCards UniProt Show fit	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr11_-_71448406 Show fit	0.85	ENST00000682708.1 ENST00000683287.1 ENST00000683714.1 ENST00000682880.1	DHCR7 Links Ensembl NCBI GeneCards UniProt Show fit	7-dehydrocholesterol reductase
chr19_-_54313074 Show fit	0.83	ENST00000486742.2 ENST00000432233.8	LILRA5 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin like receptor A5
chr4_-_68951763 Show fit	0.83	ENST00000251566.9	UGT2A3 Links Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member A3
chr4_+_26319636 Show fit	0.69	ENST00000342295.6 ENST00000506956.5 ENST00000512671.6 ENST00000345843.8	RBPJ Links Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr8_+_2045037 Show fit	0.65	ENST00000262113.9	MYOM2 Links Ensembl NCBI GeneCards UniProt Show fit	myomesin 2
chr17_-_19745602 Show fit	0.63	ENST00000444455.5 ENST00000439102.6	ALDH3A1 Links Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 3 family member A1
chr18_+_63887698 Show fit	0.55	ENST00000457692.5 ENST00000299502.9 ENST00000413956.5	SERPINB2 Links Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 2
chr4_-_167234426 Show fit	0.53	ENST00000541354.5 ENST00000509854.5 ENST00000512681.5 ENST00000357545.9 ENST00000510741.5 ENST00000510403.5	SPOCK3 Links Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr12_-_10453330 Show fit	0.49	ENST00000347831.9 ENST00000359151.8	KLRC1 Links Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor C1
chr6_-_127459364 Show fit	0.39	ENST00000487331.2 ENST00000483725.8	KIAA0408 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0408
chr19_-_57457140 Show fit	0.31	ENST00000321039.5	VN1R1 Links Ensembl NCBI GeneCards UniProt Show fit	vomeronasal 1 receptor 1
chr16_+_33827140 Show fit	0.25	ENST00000562905.2	IGHV3OR16-13 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr1_+_78620722 Show fit	0.19	ENST00000679848.1	IFI44L Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein 44 like
chr20_-_44960348 Show fit	0.14	ENST00000372813.4	TOMM34 Links Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 34
chr6_-_26271815 Show fit	0.11	ENST00000614378.1	H3C8 Links Ensembl NCBI GeneCards UniProt Show fit	H3 clustered histone 8
chr1_+_150926336 Show fit	0.11	ENST00000271640.9 ENST00000448029.5 ENST00000368962.6 ENST00000534805.5 ENST00000368969.8 ENST00000368963.5 ENST00000498193.5	SETDB1 Links Ensembl NCBI GeneCards UniProt Show fit	SET domain bifurcated histone lysine methyltransferase 1
chr2_+_156473569 Show fit	0.00	ENST00000409674.5 ENST00000409125.8	GPD2 Links Ensembl NCBI GeneCards UniProt Show fit	glycerol-3-phosphate dehydrogenase 2

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.9	35.8	GO:0002188	translation reinitiation(GO:0002188)
6.8	20.5	GO:0035744	T-helper 1 cell cytokine production(GO:0035744)
4.6	13.9	GO:1904772	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
3.9	11.7	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
3.0	11.9	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
1.9	11.5	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
1.9	13.3	GO:0061198	fungiform papilla formation(GO:0061198)
1.9	28.0	GO:0001778	plasma membrane repair(GO:0001778)
1.8	7.0	GO:0071733	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.6	12.8	GO:0075525	viral translational termination-reinitiation(GO:0075525)
1.5	3.1	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.4	5.5	GO:1903976	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) negative regulation of glial cell migration(GO:1903976)
1.3	4.0	GO:0016487	sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
1.3	9.1	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
1.1	6.8	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
1.1	14.5	GO:0042407	cristae formation(GO:0042407)
1.1	5.6	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
1.1	14.4	GO:0038203	TORC2 signaling(GO:0038203)
1.0	6.0	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
1.0	9.6	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.9	18.4	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.9	4.5	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.9	9.6	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.8	9.3	GO:0048194	Golgi vesicle budding(GO:0048194)
0.8	6.4	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.8	15.2	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.8	8.8	GO:0042262	DNA protection(GO:0042262)
0.8	3.9	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.8	4.6	GO:0035803	egg coat formation(GO:0035803)
0.7	6.5	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.7	4.1	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.7	6.1	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.6	4.3	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.6	1.8	GO:2001183	negative regulation of interleukin-12 secretion(GO:2001183)
0.6	5.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.6	18.7	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.6	42.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.5	3.8	GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.5	7.0	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.5	3.7	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
0.5	19.0	GO:0019985	translesion synthesis(GO:0019985)
0.5	7.9	GO:0032836	glomerular basement membrane development(GO:0032836)
0.5	12.1	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.5	8.6	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.4	4.0	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781) protein O-linked fucosylation(GO:0036066)
0.4	2.4	GO:0006196	AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.3	3.8	GO:0034501	protein localization to kinetochore(GO:0034501)
0.3	2.0	GO:0009441	glycolate metabolic process(GO:0009441)
0.3	29.5	GO:0006958	complement activation, classical pathway(GO:0006958)
0.3	10.7	GO:0061641	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3	11.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.3	11.5	GO:0019731	antibacterial humoral response(GO:0019731)
0.3	1.5	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.2	4.7	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2	13.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.2	4.7	GO:0070914	UV-damage excision repair(GO:0070914)
0.2	2.6	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2	3.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.2	4.5	GO:0052695	cellular glucuronidation(GO:0052695)
0.2	3.9	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.2	1.3	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.2	18.7	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
0.2	12.4	GO:0021795	cerebral cortex cell migration(GO:0021795)
0.2	2.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.2	2.2	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.1	7.6	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.1	0.9	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1	22.1	GO:0002377	immunoglobulin production(GO:0002377)
0.1	10.7	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.1	2.6	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	9.0	GO:0000045	autophagosome assembly(GO:0000045)
0.1	1.0	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.1	0.7	GO:1905068	arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1	0.9	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	1.8	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	6.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.6	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	1.0	GO:0002295	T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 cell lineage commitment(GO:0072540)
0.1	1.6	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	4.1	GO:0021983	pituitary gland development(GO:0021983)
0.1	2.1	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1	1.6	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	10.1	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	2.1	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	3.7	GO:0006081	cellular aldehyde metabolic process(GO:0006081)
0.0	5.8	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	4.2	GO:0060021	palate development(GO:0060021)
0.0	1.3	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.1	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0	2.2	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.5	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	5.0	GO:0097480	synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
0.0	1.3	GO:0010107	potassium ion import(GO:0010107)
0.0	1.9	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	5.5	GO:0051168	nuclear export(GO:0051168)
0.0	7.3	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.0	2.1	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	5.5	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.0	2.1	GO:0006479	protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0	2.6	GO:0000209	protein polyubiquitination(GO:0000209)
0.0	13.3	GO:1903507	negative regulation of nucleic acid-templated transcription(GO:1903507)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	18.7	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
2.4	14.5	GO:0061617	MICOS complex(GO:0061617)
2.4	12.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
2.1	6.4	GO:0033565	ESCRT-0 complex(GO:0033565)
1.3	12.8	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.3	15.2	GO:0008290	F-actin capping protein complex(GO:0008290)
1.0	3.9	GO:0035363	histone locus body(GO:0035363)
0.9	11.7	GO:0008385	IkappaB kinase complex(GO:0008385)
0.9	11.5	GO:0033093	Weibel-Palade body(GO:0033093)
0.9	13.9	GO:0045120	pronucleus(GO:0045120)
0.9	4.3	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.8	42.2	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.7	3.7	GO:0016589	NURF complex(GO:0016589)
0.7	7.0	GO:0097255	R2TP complex(GO:0097255)
0.7	14.4	GO:0031932	TORC2 complex(GO:0031932)
0.7	13.3	GO:0016580	Sin3 complex(GO:0016580)
0.6	44.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.4	4.7	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.4	10.7	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.4	8.5	GO:0071141	SMAD protein complex(GO:0071141)
0.4	8.5	GO:0046930	pore complex(GO:0046930)
0.4	1.8	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.4	2.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.3	3.8	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.3	12.6	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.3	2.2	GO:0060091	kinocilium(GO:0060091)
0.2	29.6	GO:0005901	caveola(GO:0005901)
0.2	5.6	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2	2.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.2	15.2	GO:0035580	specific granule lumen(GO:0035580)
0.2	5.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	18.3	GO:0045335	phagocytic vesicle(GO:0045335)
0.1	1.3	GO:0097452	GAIT complex(GO:0097452)
0.1	1.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	12.2	GO:0072686	mitotic spindle(GO:0072686)
0.1	6.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	8.7	GO:0005776	autophagosome(GO:0005776)
0.1	10.7	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.1	16.9	GO:0043679	axon terminus(GO:0043679)
0.1	1.6	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	3.7	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	1.8	GO:0036020	endolysosome membrane(GO:0036020)
0.1	1.9	GO:0005686	U2 snRNP(GO:0005686)
0.1	2.1	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.1	9.0	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	0.7	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	5.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	9.6	GO:0016605	PML body(GO:0016605)
0.1	4.0	GO:0005801	cis-Golgi network(GO:0005801)
0.1	2.6	GO:0030673	axolemma(GO:0030673)
0.1	9.8	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	5.9	GO:0030175	filopodium(GO:0030175)
0.1	5.9	GO:0072562	blood microparticle(GO:0072562)
0.0	3.0	GO:0015030	Cajal body(GO:0015030)
0.0	12.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	15.9	GO:0005769	early endosome(GO:0005769)
0.0	11.7	GO:0034774	secretory granule lumen(GO:0034774)
0.0	1.6	GO:0008180	COP9 signalosome(GO:0008180) cell cortex region(GO:0099738)
0.0	3.8	GO:0005796	Golgi lumen(GO:0005796)
0.0	11.0	GO:0031965	nuclear membrane(GO:0031965)
0.0	7.6	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	10.7	GO:0016607	nuclear speck(GO:0016607)
0.0	6.1	GO:0035770	ribonucleoprotein granule(GO:0035770)
0.0	0.6	GO:0032982	myosin filament(GO:0032982)
0.0	16.1	GO:0005615	extracellular space(GO:0005615)
0.0	5.3	GO:0019866	organelle inner membrane(GO:0019866)
0.0	2.6	GO:0016604	nuclear body(GO:0016604)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
1.7	8.6	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
1.5	11.7	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
1.4	7.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
1.3	4.0	GO:0047787	geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
1.3	8.8	GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
1.2	4.7	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.2	7.0	GO:0035500	MH2 domain binding(GO:0035500)
1.1	9.1	GO:0019863	IgE binding(GO:0019863)
1.1	11.0	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
1.1	12.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.1	4.3	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.1	8.5	GO:0015288	porin activity(GO:0015288)
1.0	13.9	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.0	18.7	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.9	3.8	GO:0043515	kinetochore binding(GO:0043515)
0.8	13.3	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.8	5.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.7	42.2	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.7	5.6	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.7	48.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.7	2.0	GO:0052852	(S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.6	3.7	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6	18.7	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.6	18.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.6	6.1	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.5	11.9	GO:0008242	omega peptidase activity(GO:0008242)
0.5	2.6	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.5	4.6	GO:0032190	acrosin binding(GO:0032190)
0.5	6.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.5	13.4	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4	11.5	GO:0031489	myosin V binding(GO:0031489)
0.4	9.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.4	9.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.3	64.9	GO:0003823	antigen binding(GO:0003823)
0.3	4.5	GO:0043522	leucine zipper domain binding(GO:0043522)
0.3	1.5	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.3	8.3	GO:0001848	complement binding(GO:0001848)
0.2	19.0	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2	3.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.2	4.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	2.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	1.6	GO:0042731	PH domain binding(GO:0042731)
0.1	1.9	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	2.6	GO:0030297	ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.9	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	14.5	GO:0032947	protein complex scaffold(GO:0032947)
0.1	3.7	GO:0001972	retinoic acid binding(GO:0001972)
0.1	1.8	GO:0017070	U6 snRNA binding(GO:0017070)
0.1	10.6	GO:0004540	ribonuclease activity(GO:0004540)
0.1	1.6	GO:0016849	phosphorus-oxygen lyase activity(GO:0016849)
0.1	8.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	2.0	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	8.6	GO:0051087	chaperone binding(GO:0051087)
0.1	1.3	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	15.8	GO:0051015	actin filament binding(GO:0051015)
0.0	12.9	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	21.5	GO:0005543	phospholipid binding(GO:0005543)
0.0	6.3	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.0	0.7	GO:0000150	recombinase activity(GO:0000150)
0.0	2.2	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	3.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.2	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	7.9	GO:0008022	protein C-terminus binding(GO:0008022)
0.0	21.6	GO:0008134	transcription factor binding(GO:0008134)
0.0	0.9	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	1.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	2.2	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	5.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	1.8	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	5.7	GO:0003924	GTPase activity(GO:0003924)
0.0	2.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	8.1	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.0	8.9	GO:0016491	oxidoreductase activity(GO:0016491)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	13.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	11.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.3	13.0	PID MYC PATHWAY	C-MYC pathway
0.2	29.6	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.2	11.6	PID IFNG PATHWAY	IFN-gamma pathway
0.2	14.4	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	9.1	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	8.3	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.1	6.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	13.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	10.7	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	2.6	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	2.1	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	3.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	4.3	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	1.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	9.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	11.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	2.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	5.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.3	PID BARD1 PATHWAY	BARD1 signaling events
0.0	2.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	4.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.3	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	10.7	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.5	11.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.4	13.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.3	24.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3	6.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.3	6.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3	11.0	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	4.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.2	1.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2	7.0	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.2	5.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	5.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.2	3.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2	2.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	3.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	5.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	6.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	3.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	2.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	2.6	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	3.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	4.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	1.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	3.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	5.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	6.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.7	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	1.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	1.3	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	2.6	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation