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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TBX2

Z-value: 2.16

Motif logo

Transcription factors associated with TBX2

Gene Symbol Gene ID Gene Info
ENSG00000121068.14 TBX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX2hg38_v1_chr17_+_61399835_61399851-0.073.3e-01Click!

Activity profile of TBX2 motif

Sorted Z-values of TBX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_51372640 12.68 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr8_+_127737610 8.37 ENST00000652288.1
MYC proto-oncogene, bHLH transcription factor
chr5_+_134525649 8.33 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chrX_+_71283186 8.32 ENST00000535149.5
non-POU domain containing octamer binding
chr1_-_112704921 8.02 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr2_+_201129318 7.99 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr12_-_55727796 7.41 ENST00000550776.5
CD63 molecule
chr7_+_116525524 7.39 ENST00000405348.6
caveolin 1
chr2_+_177392734 7.34 ENST00000680770.1
ENST00000637633.2
ENST00000679459.1
ENST00000409888.1
ENST00000264167.11
ENST00000642466.2
alkylglycerone phosphate synthase
chr11_-_58578096 7.34 ENST00000528954.5
ENST00000528489.1
leupaxin
chr12_-_14951106 7.33 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr15_-_55289756 7.32 ENST00000336787.6
RAB27A, member RAS oncogene family
chr10_+_52314272 7.11 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr19_-_51372686 7.08 ENST00000595217.1
natural killer cell granule protein 7
chr11_-_615570 6.52 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr19_-_51372269 6.49 ENST00000593572.5
ENST00000595157.1
natural killer cell granule protein 7
chr12_+_95858928 6.49 ENST00000266735.9
ENST00000553192.5
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr12_-_48924919 6.37 ENST00000444214.6
FKBP prolyl isomerase 11
chr12_-_55727828 6.24 ENST00000546939.5
CD63 molecule
chr12_-_55728436 6.09 ENST00000552692.5
CD63 molecule
chr17_+_37489882 6.06 ENST00000617516.5
dual specificity phosphatase 14
chr8_+_2045058 6.05 ENST00000523438.1
myomesin 2
chr3_-_32502783 5.73 ENST00000205636.4
CKLF like MARVEL transmembrane domain containing 6
chr5_+_35856883 5.72 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr1_+_32251239 5.71 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK proto-oncogene, Src family tyrosine kinase
chr16_-_88651015 5.66 ENST00000568278.1
ENST00000569359.5
ENST00000567174.5
ENST00000261623.8
cytochrome b-245 alpha chain
chr15_+_41332862 5.61 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr7_+_73692596 5.60 ENST00000453316.1
BUD23 rRNA methyltransferase and ribosome maturation factor
chrX_-_53434341 5.58 ENST00000375298.4
ENST00000375304.9
ENST00000684692.1
ENST00000168216.11
hydroxysteroid 17-beta dehydrogenase 10
chr12_-_55728339 5.55 ENST00000552754.5
CD63 molecule
chr15_+_63504511 5.39 ENST00000540797.5
ubiquitin specific peptidase 3
chr3_+_160399630 5.31 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
structural maintenance of chromosomes 4
chr22_+_24555981 5.16 ENST00000215829.8
ENST00000402849.5
small nuclear ribonucleoprotein D3 polypeptide
chr12_+_21372899 4.97 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr2_+_201129483 4.90 ENST00000440180.5
CASP8 and FADD like apoptosis regulator
chr9_+_128689948 4.83 ENST00000372688.8
ENST00000372686.5
SET nuclear proto-oncogene
chr22_+_38201932 4.67 ENST00000538999.1
ENST00000538320.5
ENST00000338483.7
ENST00000441709.1
MAF bZIP transcription factor F
chr15_+_63504583 4.67 ENST00000380324.8
ENST00000561442.5
ENST00000560070.5
ubiquitin specific peptidase 3
chr7_+_16661182 4.67 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
basic leucine zipper and W2 domains 2
chr11_+_108665045 4.62 ENST00000322536.8
DEAD-box helicase 10
chr11_-_14359118 4.60 ENST00000256196.9
RAS related 2
chr12_+_75481204 4.55 ENST00000550491.1
GLI pathogenesis related 1
chr19_-_38617928 4.52 ENST00000396857.7
ENST00000586296.5
mitogen-activated protein kinase kinase kinase kinase 1
chr19_+_35745590 4.46 ENST00000591949.1
presenilin enhancer, gamma-secretase subunit
chr19_+_35745613 4.44 ENST00000222266.2
ENST00000587708.7
presenilin enhancer, gamma-secretase subunit
chr19_-_17405554 4.39 ENST00000252593.7
bone marrow stromal cell antigen 2
chr22_+_40045451 4.36 ENST00000402203.5
trinucleotide repeat containing adaptor 6B
chr19_-_38617912 4.32 ENST00000591517.5
mitogen-activated protein kinase kinase kinase kinase 1
chr21_+_29130630 4.31 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr11_-_615921 4.14 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
interferon regulatory factor 7
chr12_+_53985138 4.14 ENST00000303460.5
homeobox C10
chr11_-_6683282 4.12 ENST00000532203.1
ENST00000288937.7
mitochondrial ribosomal protein L17
chrX_-_120559889 4.04 ENST00000371323.3
cullin 4B
chr19_+_52429181 3.96 ENST00000301085.8
zinc finger protein 534
chr14_-_55191534 3.92 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chrX_-_120575783 3.89 ENST00000680673.1
cullin 4B
chr19_+_13151975 3.88 ENST00000588173.1
immediate early response 2
chr19_-_43198079 3.84 ENST00000597374.5
ENST00000599371.1
pregnancy specific beta-1-glycoprotein 4
chr19_+_47130782 3.84 ENST00000597808.5
ENST00000413379.7
ENST00000600706.5
ENST00000270225.12
ENST00000598840.5
ENST00000600753.1
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr1_+_40979659 3.82 ENST00000650070.2
ENST00000649864.1
ENST00000649124.1
CTP synthase 1
chr10_+_93496599 3.73 ENST00000371485.8
centrosomal protein 55
chr12_-_55728640 3.71 ENST00000551173.5
ENST00000420846.7
CD63 molecule
chr17_-_7687427 3.69 ENST00000514944.5
ENST00000503591.1
ENST00000610292.4
ENST00000420246.6
ENST00000455263.6
ENST00000610538.4
ENST00000622645.4
ENST00000445888.6
ENST00000619485.4
ENST00000509690.5
ENST00000604348.5
ENST00000269305.9
ENST00000620739.4
tumor protein p53
chr11_+_122838492 3.64 ENST00000227348.9
cytotoxic and regulatory T cell molecule
chr14_-_106627685 3.62 ENST00000390629.3
immunoglobulin heavy variable 4-59
chrX_+_110002635 3.59 ENST00000372072.7
transmembrane protein 164
chr1_-_12616762 3.50 ENST00000464917.5
dehydrogenase/reductase 3
chr2_-_199457931 3.49 ENST00000417098.6
SATB homeobox 2
chr6_+_32968557 3.49 ENST00000374825.9
bromodomain containing 2
chr6_-_89352706 3.49 ENST00000435041.3
ubiquitin conjugating enzyme E2 J1
chr10_-_70602687 3.43 ENST00000638674.1
perforin 1
chr5_-_44389407 3.43 ENST00000264664.5
fibroblast growth factor 10
chr12_-_55727044 3.41 ENST00000548160.5
CD63 molecule
chr2_-_168913277 3.38 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr19_-_14517425 3.36 ENST00000676577.1
ENST00000677204.1
ENST00000598235.2
DnaJ heat shock protein family (Hsp40) member B1
chr2_-_234497035 3.36 ENST00000390645.2
ENST00000339728.6
ADP ribosylation factor like GTPase 4C
chr12_-_110742839 3.35 ENST00000551676.5
ENST00000550991.5
ENST00000335007.10
protein phosphatase 1 catalytic subunit gamma
chr14_-_24195334 3.34 ENST00000530563.1
ENST00000528895.5
ENST00000528669.5
ENST00000532632.1
ENST00000261789.9
transmembrane 9 superfamily member 1
chr16_-_57447366 3.34 ENST00000567751.5
ENST00000568940.5
ENST00000563341.1
ENST00000394391.9
ENST00000565961.5
ENST00000569370.5
ENST00000567518.5
ENST00000565786.5
cytokine induced apoptosis inhibitor 1
chr2_-_191014137 3.29 ENST00000673777.1
ENST00000673942.1
ENST00000424722.6
ENST00000392322.7
ENST00000361099.8
ENST00000392323.6
ENST00000673816.1
ENST00000673847.1
ENST00000673952.1
ENST00000540176.6
ENST00000673841.1
signal transducer and activator of transcription 1
chr12_-_110742929 3.23 ENST00000340766.9
protein phosphatase 1 catalytic subunit gamma
chr5_-_72320217 3.17 ENST00000508863.6
ENST00000522095.1
ENST00000513900.5
ENST00000515404.5
ENST00000261413.10
ENST00000457646.8
mitochondrial ribosomal protein S27
chr17_+_50746614 3.17 ENST00000513969.5
ENST00000503728.1
LUC7 like 3 pre-mRNA splicing factor
chr11_+_126304041 3.15 ENST00000263579.5
decapping enzyme, scavenger
chr3_+_42149222 3.15 ENST00000449246.5
ENST00000613405.4
trafficking kinesin protein 1
chr16_-_4345904 3.14 ENST00000571941.5
presequence translocase associated motor 16
chr12_-_120581361 3.13 ENST00000341039.6
ENST00000357500.5
POP5 homolog, ribonuclease P/MRP subunit
chr6_+_30717433 3.11 ENST00000681435.1
tubulin beta class I
chr19_+_35031263 3.10 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr6_+_26383176 3.10 ENST00000416795.6
ENST00000494184.1
butyrophilin subfamily 2 member A2
chr6_-_159745186 3.06 ENST00000537657.5
superoxide dismutase 2
chr14_-_75176593 3.04 ENST00000303575.9
transmembrane p24 trafficking protein 10
chr16_-_66934144 3.01 ENST00000568572.5
cytosolic iron-sulfur assembly component 2B
chr17_+_36949285 3.00 ENST00000681062.1
ENST00000679881.1
ENST00000680782.1
apoptosis antagonizing transcription factor
chr1_-_6200831 2.99 ENST00000497965.5
ribosomal protein L22
chr1_+_93079264 2.98 ENST00000370298.9
ENST00000370303.4
metal response element binding transcription factor 2
chr12_+_103930600 2.97 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chr12_-_55728977 2.88 ENST00000552164.5
CD63 molecule
chr12_-_55727080 2.87 ENST00000548898.5
ENST00000552067.5
CD63 molecule
chr2_-_177392673 2.86 ENST00000447413.1
ENST00000397057.6
ENST00000456746.5
ENST00000464747.5
novel transcript
nuclear factor, erythroid 2 like 2
chr11_-_27722021 2.83 ENST00000314915.6
brain derived neurotrophic factor
chr5_-_177006350 2.82 ENST00000377227.8
ubiquitin interaction motif containing 1
chr1_+_38991239 2.81 ENST00000432648.8
ENST00000446189.6
ENST00000372984.8
akirin 1
chr1_+_16440700 2.79 ENST00000504551.6
ENST00000457722.6
ENST00000337132.10
ENST00000443980.6
NECAP endocytosis associated 2
chr1_+_161766282 2.79 ENST00000680688.1
activating transcription factor 6
chr19_-_46850286 2.78 ENST00000601498.5
adaptor related protein complex 2 subunit sigma 1
chr6_+_113857333 2.78 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr12_+_93571832 2.78 ENST00000549887.1
suppressor of cytokine signaling 2
chr1_+_101237009 2.77 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr5_+_55024250 2.76 ENST00000231009.3
granzyme K
chr17_-_63873676 2.76 ENST00000613718.3
ENST00000392886.7
ENST00000345366.8
ENST00000336844.9
ENST00000560142.5
chorionic somatomammotropin hormone 2
chr5_-_133968578 2.74 ENST00000231512.5
chromosome 5 open reading frame 15
chr17_-_1684807 2.71 ENST00000577001.1
ENST00000572621.5
ENST00000304992.11
pre-mRNA processing factor 8
chr19_+_12938598 2.63 ENST00000586760.2
ENST00000316448.10
ENST00000588454.6
calreticulin
chr11_-_111879425 2.58 ENST00000622211.4
novel protein
chr14_-_35121950 2.57 ENST00000554361.5
ENST00000261475.10
protein phosphatase 2 regulatory subunit B''gamma
chr12_-_55728994 2.55 ENST00000257857.9
CD63 molecule
chr2_-_25878445 2.54 ENST00000336112.9
ENST00000435504.9
ASXL transcriptional regulator 2
chr5_+_83471925 2.52 ENST00000502527.2
versican
chr2_+_188291854 2.43 ENST00000409830.6
GULP PTB domain containing engulfment adaptor 1
chr2_-_208254232 2.41 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chr8_-_123416327 2.40 ENST00000521903.5
ATPase family AAA domain containing 2
chr16_+_85611401 2.39 ENST00000405402.6
Gse1 coiled-coil protein
chr1_+_20589044 2.38 ENST00000375071.4
cytidine deaminase
chr13_+_30713477 2.35 ENST00000617770.4
arachidonate 5-lipoxygenase activating protein
chr5_+_53560627 2.35 ENST00000296684.10
ENST00000506765.1
NADH:ubiquinone oxidoreductase subunit S4
chr6_-_28923932 2.29 ENST00000377199.4
ENST00000377194.7
tripartite motif containing 27
chr6_-_24935942 2.24 ENST00000645100.1
ENST00000643898.2
ENST00000613507.4
RHO family interacting cell polarization regulator 2
chr17_+_36103819 2.17 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr17_-_41811930 2.15 ENST00000393928.6
prolyl 3-hydroxylase family member 4 (inactive)
chr9_-_124415421 2.12 ENST00000259457.8
ENST00000441097.1
proteasome 20S subunit beta 7
chr6_+_43132472 2.12 ENST00000489707.5
protein tyrosine kinase 7 (inactive)
chr11_+_114400030 2.12 ENST00000540163.5
RNA binding motif protein 7
chrX_-_10677720 2.09 ENST00000453318.6
midline 1
chr3_+_158110052 2.09 ENST00000295930.7
ENST00000471994.5
ENST00000482822.3
ENST00000476899.6
ENST00000683899.1
ENST00000684604.1
ENST00000682164.1
ENST00000464171.5
ENST00000611884.5
ENST00000312179.10
ENST00000475278.6
arginine and serine rich coiled-coil 1
chr9_-_130043154 2.08 ENST00000355681.3
ENST00000446176.7
ENST00000443566.6
ENST00000420781.5
formin binding protein 1
chr17_+_59893046 2.07 ENST00000393021.7
ENST00000225577.9
ENST00000443572.6
ENST00000406116.7
ribosomal protein S6 kinase B1
chr11_-_66345066 2.06 ENST00000359957.8
ENST00000425825.6
BRMS1 transcriptional repressor and anoikis regulator
chr7_+_100673823 2.04 ENST00000419828.5
ENST00000427895.5
G protein subunit beta 2
chr3_+_112990956 2.03 ENST00000383678.8
ENST00000383677.7
ENST00000619116.4
GTP binding protein 8 (putative)
chr19_-_43670153 2.02 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
plasminogen activator, urokinase receptor
chr13_+_33818122 1.99 ENST00000380071.8
replication factor C subunit 3
chr3_+_184315347 1.98 ENST00000424196.5
eukaryotic translation initiation factor 4 gamma 1
chr19_-_45478817 1.97 ENST00000423698.6
ERCC excision repair 1, endonuclease non-catalytic subunit
chr1_-_53945567 1.97 ENST00000371378.6
heat shock protein family B (small) member 11
chr1_-_150808251 1.97 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
cathepsin K
chr17_-_63911236 1.92 ENST00000438387.6
ENST00000346606.10
ENST00000309894.6
ENST00000561003.5
ENST00000450719.3
ENST00000259003.14
chorionic somatomammotropin hormone like 1
chr16_+_27402167 1.91 ENST00000564089.5
ENST00000337929.8
interleukin 21 receptor
chr4_+_94451857 1.91 ENST00000318007.9
ENST00000380180.7
ENST00000437932.5
ENST00000615540.4
ENST00000359265.8
ENST00000512274.1
ENST00000503974.5
ENST00000504489.3
ENST00000317968.9
ENST00000542407.5
PDZ and LIM domain 5
chr1_+_93079234 1.91 ENST00000540243.5
ENST00000545708.5
metal response element binding transcription factor 2
chr22_+_24427587 1.90 ENST00000337539.12
adenosine A2a receptor
chr1_+_161766309 1.90 ENST00000679853.1
ENST00000681492.1
ENST00000679886.1
ENST00000367942.4
ENST00000680462.1
ENST00000680633.1
ENST00000681912.1
activating transcription factor 6
chr14_-_23435652 1.89 ENST00000355349.4
myosin heavy chain 7
chr16_+_11965193 1.88 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr5_-_71067601 1.87 ENST00000274400.9
ENST00000521602.2
ENST00000330280.11
ENST00000517900.5
general transcription factor IIH subunit 2
chr17_-_41812586 1.85 ENST00000355468.7
ENST00000590496.1
prolyl 3-hydroxylase family member 4 (inactive)
chr8_+_2045037 1.83 ENST00000262113.9
myomesin 2
chr12_+_93572664 1.82 ENST00000551556.2
suppressor of cytokine signaling 2
chr6_+_43635832 1.81 ENST00000372171.5
MAD2L1 binding protein
chr1_+_111619751 1.78 ENST00000433097.5
ENST00000369709.3
RAP1A, member of RAS oncogene family
chr7_+_100428782 1.77 ENST00000414441.5
methylphosphate capping enzyme
chr6_+_30617825 1.74 ENST00000259873.5
mitochondrial ribosomal protein S18B
chr15_-_74873310 1.73 ENST00000562363.5
ENST00000564529.1
ENST00000268099.13
secretory carrier membrane protein 2
chr14_-_103562257 1.73 ENST00000337322.4
ENST00000445922.2
BAG cochaperone 5
chr5_+_163505564 1.69 ENST00000421814.6
ENST00000518095.5
ENST00000321757.11
methionine adenosyltransferase 2B
chr13_-_40666600 1.68 ENST00000379561.6
forkhead box O1
chr3_+_184299198 1.67 ENST00000417952.5
ENST00000310118.9
proteasome 26S subunit, non-ATPase 2
chr15_-_34795541 1.66 ENST00000290378.6
actin alpha cardiac muscle 1
chrX_+_100644183 1.66 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr1_-_200620729 1.66 ENST00000367350.5
kinesin family member 14
chr6_+_26383090 1.65 ENST00000469230.5
ENST00000490025.5
ENST00000352867.6
ENST00000356709.9
ENST00000493275.5
ENST00000472507.5
ENST00000482536.5
ENST00000432533.6
ENST00000482842.1
butyrophilin subfamily 2 member A2
chr1_-_21937300 1.65 ENST00000374695.8
heparan sulfate proteoglycan 2
chr12_+_122752814 1.62 ENST00000455982.2
ENST00000280557.11
density regulated re-initiation and release factor
chr21_-_45542465 1.59 ENST00000380010.8
solute carrier family 19 member 1
chr16_+_11965234 1.54 ENST00000562385.1
TNF receptor superfamily member 17
chr6_-_31652358 1.52 ENST00000456622.5
ENST00000435080.5
ENST00000375976.8
ENST00000441054.5
BAG cochaperone 6
chr11_-_28108109 1.51 ENST00000263181.7
kinesin family member 18A
chr5_+_141192330 1.51 ENST00000239446.6
protocadherin beta 10
chr10_-_110918934 1.50 ENST00000605742.5
BBSome interacting protein 1
chr1_-_53945584 1.50 ENST00000371377.3
heat shock protein family B (small) member 11
chr17_+_48107743 1.48 ENST00000359238.7
ENST00000582104.5
ENST00000584335.5
sorting nexin 11
chr19_-_54364983 1.48 ENST00000434277.6
leukocyte associated immunoglobulin like receptor 1
chr5_-_9630351 1.44 ENST00000382492.4
taste 2 receptor member 1
chr13_-_75366973 1.44 ENST00000648194.1
TBC1 domain family member 4
chr8_+_21966215 1.43 ENST00000433566.8
exportin 7
chr21_-_45563115 1.43 ENST00000650808.1
solute carrier family 19 member 1
chr12_-_7872902 1.42 ENST00000431042.7
solute carrier family 2 member 14
chr1_-_205321737 1.38 ENST00000367157.6
NUAK family kinase 2
chr3_+_158110363 1.37 ENST00000683137.1
arginine and serine rich coiled-coil 1
chr19_-_54364863 1.36 ENST00000348231.8
leukocyte associated immunoglobulin like receptor 1
chr8_+_109086585 1.36 ENST00000518632.2
thyrotropin releasing hormone receptor
chr22_-_42519782 1.35 ENST00000323013.7
ribosomal RNA processing 7 homolog A
chr4_+_26320563 1.32 ENST00000361572.10
recombination signal binding protein for immunoglobulin kappa J region
chr11_+_2382460 1.31 ENST00000492627.5
CD81 molecule
chr8_-_67062120 1.30 ENST00000357849.9
COP9 signalosome subunit 5
chr7_+_99438919 1.28 ENST00000436336.6
ENST00000292476.10
ENST00000451876.5
cleavage and polyadenylation specific factor 4
chr19_-_54364807 1.27 ENST00000474878.5
leukocyte associated immunoglobulin like receptor 1
chr20_-_24992682 1.27 ENST00000217456.3
adipocyte plasma membrane associated protein
chr7_+_832488 1.27 ENST00000405266.5
ENST00000403868.5
ENST00000425407.6
Sad1 and UNC84 domain containing 1
chr19_-_54364908 1.26 ENST00000391742.7
leukocyte associated immunoglobulin like receptor 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 40.7 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
2.4 7.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
2.4 7.3 GO:0071461 cellular response to redox state(GO:0071461)
2.4 7.1 GO:0009996 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996)
2.1 10.7 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
2.1 8.4 GO:0090096 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
1.9 5.7 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.9 5.6 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
1.9 5.6 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
1.8 7.4 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.6 8.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
1.5 4.4 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
1.2 3.7 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
1.2 7.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
1.2 4.9 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
1.2 7.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.2 12.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.1 3.4 GO:0071338 male genitalia morphogenesis(GO:0048808) bronchiole development(GO:0060435) submandibular salivary gland formation(GO:0060661) positive regulation of fat cell proliferation(GO:0070346) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) male anatomical structure morphogenesis(GO:0090598)
1.1 3.3 GO:0072183 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
1.0 3.1 GO:0036245 cellular response to menadione(GO:0036245)
1.0 7.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.0 3.8 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.9 2.8 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.9 2.8 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.9 5.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.9 2.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.9 3.4 GO:0002357 defense response to tumor cell(GO:0002357)
0.8 2.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.8 3.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.8 7.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.8 2.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.8 3.0 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.7 2.9 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.7 2.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.7 2.0 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.7 4.7 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.7 3.9 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.6 8.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.6 5.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.6 3.1 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.6 3.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.6 3.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.5 5.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.5 9.9 GO:0070914 UV-damage excision repair(GO:0070914)
0.5 3.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.5 1.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.5 3.0 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.5 2.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.5 2.5 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.5 2.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5 1.9 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.5 7.7 GO:0007220 Notch receptor processing(GO:0007220)
0.4 2.2 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.4 1.8 GO:0097327 response to antineoplastic agent(GO:0097327)
0.4 3.5 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.4 1.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.4 1.7 GO:1902617 response to fluoride(GO:1902617)
0.4 1.6 GO:0002188 translation reinitiation(GO:0002188)
0.4 2.8 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.4 2.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.4 1.2 GO:0042704 uterine wall breakdown(GO:0042704)
0.4 1.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 2.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.4 9.8 GO:0016578 histone deubiquitination(GO:0016578)
0.4 4.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.4 2.6 GO:0060844 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.4 2.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 14.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 3.1 GO:0009249 protein lipoylation(GO:0009249)
0.3 1.7 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.3 8.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 1.7 GO:0090131 mesenchyme migration(GO:0090131)
0.3 2.6 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.3 1.3 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.3 3.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 1.9 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.3 2.8 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.3 3.6 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.3 2.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 0.6 GO:0019249 lactate biosynthetic process(GO:0019249)
0.3 5.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.3 1.7 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.3 4.4 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.3 3.0 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.3 4.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.3 1.1 GO:0051582 peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.3 2.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.3 2.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 6.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.3 1.3 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.3 4.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.3 1.8 GO:0040031 snRNA modification(GO:0040031)
0.2 0.7 GO:1902896 terminal web assembly(GO:1902896)
0.2 3.7 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.2 1.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 2.7 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.2 2.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 2.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 2.5 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 3.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 1.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 3.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 1.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 3.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 2.2 GO:0070986 left/right axis specification(GO:0070986)
0.2 0.6 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 2.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.2 0.7 GO:0035627 ceramide transport(GO:0035627)
0.2 4.2 GO:0007567 parturition(GO:0007567)
0.2 4.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 1.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.2 0.5 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 6.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 2.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 3.8 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 3.0 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.7 GO:0035803 egg coat formation(GO:0035803)
0.1 9.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.4 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.1 2.8 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.1 2.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.3 GO:0000338 protein deneddylation(GO:0000338)
0.1 1.9 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 1.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 1.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.7 GO:0061042 vascular wound healing(GO:0061042)
0.1 1.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 1.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 1.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 3.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 2.9 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 4.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 3.4 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.4 GO:0007635 chemosensory behavior(GO:0007635)
0.1 0.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 1.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.8 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.5 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.1 0.9 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1 0.4 GO:0032202 telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666)
0.1 3.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.7 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 2.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.6 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 3.5 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 5.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.5 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 1.6 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 2.3 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 1.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 1.9 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 7.1 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0 3.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 1.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 5.8 GO:0007051 spindle organization(GO:0007051)
0.0 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 2.8 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.4 GO:0021756 striatum development(GO:0021756)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.9 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 1.6 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 2.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.3 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.6 GO:0051321 meiotic cell cycle(GO:0051321)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 40.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.7 11.7 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
1.3 11.9 GO:0070765 gamma-secretase complex(GO:0070765)
1.1 3.4 GO:0031262 Ndc80 complex(GO:0031262)
1.0 3.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.9 8.3 GO:0042382 paraspeckles(GO:0042382)
0.8 3.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.7 7.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.7 10.1 GO:0070938 contractile ring(GO:0070938)
0.7 8.7 GO:0030677 ribonuclease P complex(GO:0030677)
0.7 5.3 GO:0000796 condensin complex(GO:0000796)
0.6 12.9 GO:0097342 ripoptosome(GO:0097342)
0.6 7.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.6 6.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.6 1.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.6 1.7 GO:0034515 proteasome storage granule(GO:0034515)
0.5 1.5 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.5 1.9 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.5 4.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.4 2.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.4 7.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 9.8 GO:0032982 myosin filament(GO:0032982)
0.4 5.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 3.4 GO:0044194 cytolytic granule(GO:0044194)
0.3 1.7 GO:0042643 actomyosin, actin portion(GO:0042643)
0.3 2.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.3 2.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 2.0 GO:0036021 endolysosome lumen(GO:0036021)
0.3 5.7 GO:0000242 pericentriolar material(GO:0000242)
0.3 3.7 GO:0090543 Flemming body(GO:0090543)
0.3 1.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 1.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 2.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.2 14.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 1.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.2 1.1 GO:0034464 BBSome(GO:0034464)
0.2 2.2 GO:0060171 stereocilium membrane(GO:0060171)
0.2 2.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 3.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 3.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 3.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 2.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 2.8 GO:0043073 germ cell nucleus(GO:0043073)
0.2 4.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 9.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 4.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 6.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.2 1.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 2.0 GO:0071438 invadopodium membrane(GO:0071438)
0.2 3.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 5.2 GO:0032420 stereocilium(GO:0032420)
0.2 0.8 GO:0001739 sex chromatin(GO:0001739)
0.2 2.1 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 1.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 2.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 4.0 GO:0000795 synaptonemal complex(GO:0000795)
0.1 3.3 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.7 GO:0051233 spindle midzone(GO:0051233)
0.1 4.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 2.1 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 2.3 GO:0030904 retromer complex(GO:0030904)
0.1 5.6 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 4.0 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.6 GO:0043196 varicosity(GO:0043196)
0.1 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 4.3 GO:0005657 replication fork(GO:0005657)
0.1 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.0 GO:0030673 axolemma(GO:0030673)
0.1 3.0 GO:0002102 podosome(GO:0002102)
0.1 5.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 6.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 4.8 GO:0005811 lipid particle(GO:0005811)
0.1 0.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 2.2 GO:0016592 mediator complex(GO:0016592)
0.1 3.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 6.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.3 GO:0030686 90S preribosome(GO:0030686)
0.0 0.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.2 GO:0031904 endosome lumen(GO:0031904)
0.0 1.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 9.6 GO:0010008 endosome membrane(GO:0010008)
0.0 1.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 1.9 GO:0097525 spliceosomal snRNP complex(GO:0097525)
0.0 2.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 21.0 GO:0005730 nucleolus(GO:0005730)
0.0 1.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.3 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.8 GO:0005769 early endosome(GO:0005769)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.3 5.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
1.1 5.7 GO:0042610 CD8 receptor binding(GO:0042610)
1.0 3.8 GO:0003883 CTP synthase activity(GO:0003883)
0.9 5.6 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.9 7.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.9 3.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.8 2.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.7 2.8 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.7 2.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.6 3.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.6 3.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.6 6.3 GO:0039706 co-receptor binding(GO:0039706)
0.6 4.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 3.0 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.5 2.7 GO:0030620 U2 snRNA binding(GO:0030620)
0.4 8.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.4 3.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 2.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 12.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 3.7 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.4 6.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 5.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.4 2.6 GO:0001849 complement component C1q binding(GO:0001849)
0.4 7.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.3 1.0 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.3 8.4 GO:0031489 myosin V binding(GO:0031489)
0.3 1.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 3.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.3 3.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 2.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.3 2.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 1.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.3 2.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 5.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 6.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.9 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 3.0 GO:0046790 virion binding(GO:0046790)
0.3 3.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.3 3.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 7.3 GO:0071949 FAD binding(GO:0071949)
0.2 1.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 2.0 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 1.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 7.1 GO:0005521 lamin binding(GO:0005521)
0.2 1.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 4.7 GO:0035497 cAMP response element binding(GO:0035497)
0.2 2.8 GO:0046625 sphingolipid binding(GO:0046625)
0.2 0.7 GO:0055100 adiponectin binding(GO:0055100)
0.2 0.8 GO:0004461 lactose synthase activity(GO:0004461)
0.2 2.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 3.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 2.6 GO:0000150 recombinase activity(GO:0000150)
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 1.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 3.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.7 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 1.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 2.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.7 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 2.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 2.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 3.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.3 GO:0004064 arylesterase activity(GO:0004064)
0.1 2.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 4.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.1 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 3.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.8 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 1.1 GO:0001851 complement component C3b binding(GO:0001851)
0.1 2.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 3.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 3.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 8.3 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 4.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 20.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 0.6 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 6.8 GO:0070888 E-box binding(GO:0070888)
0.1 1.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.6 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1 7.9 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 3.5 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 2.1 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 4.7 GO:0005080 protein kinase C binding(GO:0005080)
0.1 4.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 2.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 11.8 GO:0003823 antigen binding(GO:0003823)
0.1 2.0 GO:0043394 proteoglycan binding(GO:0043394)
0.1 0.8 GO:0004697 protein kinase C activity(GO:0004697)
0.1 7.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.0 2.3 GO:0008137 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 8.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 11.9 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 1.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.8 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 2.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 4.4 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 8.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.8 GO:0005525 GTP binding(GO:0005525)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 6.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.4 11.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4 26.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 7.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 3.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 8.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 11.9 PID AURORA B PATHWAY Aurora B signaling
0.2 5.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 5.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 2.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 5.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 7.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 5.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 5.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 4.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.5 PID ATM PATHWAY ATM pathway
0.1 4.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 2.8 PID SHP2 PATHWAY SHP2 signaling
0.1 2.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 7.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 4.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 2.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.8 PID FOXO PATHWAY FoxO family signaling
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 9.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.7 10.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 8.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.6 9.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4 14.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 11.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.4 10.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 5.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.3 9.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 3.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 4.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 2.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 2.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 9.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 5.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 8.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 10.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 28.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 8.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 2.0 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 3.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 5.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 2.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 3.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 4.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.0 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 2.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 3.8 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 1.5 REACTOME KINESINS Genes involved in Kinesins
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 3.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 5.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 7.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 4.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.9 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 2.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.3 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing