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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TBX21_TBR1

Z-value: 4.30

Motif logo

Transcription factors associated with TBX21_TBR1

Gene Symbol Gene ID Gene Info
ENSG00000073861.3 TBX21
ENSG00000136535.15 TBR1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX21hg38_v1_chr17_+_47733228_477332420.522.8e-16Click!
TBR1hg38_v1_chr2_+_161416273_1614163250.252.2e-04Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_55024250 16.99 ENST00000231009.3
granzyme K
chr14_+_75278820 13.97 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr5_+_176238365 11.33 ENST00000341199.10
ENST00000430704.6
ENST00000443967.5
ENST00000429602.7
SUMO interacting motifs containing 1
chr5_-_131796921 9.46 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr8_+_2045058 9.33 ENST00000523438.1
myomesin 2
chr14_+_75280078 9.32 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr7_-_36724380 9.29 ENST00000617267.4
acyloxyacyl hydrolase
chr17_+_36103819 9.08 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr5_-_131797030 8.89 ENST00000615660.4
folliculin interacting protein 1
chr14_+_94612383 8.81 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr7_-_36724543 8.80 ENST00000612871.4
acyloxyacyl hydrolase
chr5_-_131796965 8.73 ENST00000514667.1
ENST00000511848.1
ENST00000510461.6
novel protein
folliculin interacting protein 1
chr2_-_156332694 8.68 ENST00000424077.1
ENST00000426264.5
ENST00000421709.1
ENST00000339562.9
nuclear receptor subfamily 4 group A member 2
chr12_+_69348372 8.56 ENST00000261267.7
ENST00000549690.1
ENST00000548839.1
lysozyme
chr9_+_17135017 8.31 ENST00000380641.4
ENST00000380647.8
centlein
chr1_+_182789765 8.20 ENST00000367555.5
ENST00000367553.6
N-acetylneuraminate pyruvate lyase
chr5_+_75512058 7.54 ENST00000514296.5
DNA polymerase kappa
chr22_+_22900976 7.50 ENST00000390323.2
immunoglobulin lambda constant 2
chr9_+_32552305 7.43 ENST00000451672.2
ENST00000644531.1
small integral membrane protein 27
chr7_-_36724457 7.37 ENST00000617537.5
ENST00000435386.1
acyloxyacyl hydrolase
chr4_+_8580387 7.32 ENST00000382487.5
G protein-coupled receptor 78
chr1_-_11848345 7.02 ENST00000376476.1
natriuretic peptide A
chr12_-_7872902 6.99 ENST00000431042.7
solute carrier family 2 member 14
chr11_+_73647549 6.87 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr12_-_7873027 6.55 ENST00000542782.5
ENST00000396589.6
ENST00000535266.5
ENST00000542505.5
solute carrier family 2 member 14
chr7_-_100428657 6.31 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr12_-_7872843 6.14 ENST00000340749.9
ENST00000535295.5
ENST00000539234.5
solute carrier family 2 member 14
chr12_-_89352395 6.12 ENST00000308385.6
dual specificity phosphatase 6
chr12_-_7872802 6.08 ENST00000535344.5
ENST00000543909.5
solute carrier family 2 member 14
chr15_-_82647503 6.06 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr22_-_17221841 6.00 ENST00000449907.7
ENST00000441548.1
ENST00000399839.5
adenosine deaminase 2
chr1_+_37556913 5.81 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr1_-_163202835 5.61 ENST00000527988.1
ENST00000531476.1
ENST00000530507.5
ENST00000313961.10
regulator of G protein signaling 5
chr19_-_38899529 5.43 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr1_+_145927105 5.34 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr10_-_70602687 5.33 ENST00000638674.1
perforin 1
chr6_-_32530268 5.29 ENST00000374975.4
major histocompatibility complex, class II, DR beta 5
chr16_-_30534819 5.14 ENST00000395094.3
zinc finger protein 747
chr11_+_112961402 5.13 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
neural cell adhesion molecule 1
chr3_+_46987972 5.00 ENST00000651747.1
neurobeachin like 2
chr19_-_51372640 4.99 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr11_-_33892010 4.97 ENST00000257818.3
LIM domain only 2
chr1_+_69567906 4.93 ENST00000651989.2
leucine rich repeat containing 7
chr19_+_36916298 4.93 ENST00000427117.5
ENST00000333987.12
ENST00000587130.5
ENST00000415168.5
ENST00000444991.5
zinc finger protein 568
chr12_-_89352487 4.88 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr15_-_82647336 4.78 ENST00000617522.4
ENST00000684509.1
cytoplasmic polyadenylation element binding protein 1
chr2_+_143129379 4.77 ENST00000295095.11
Rho GTPase activating protein 15
chr10_+_116545907 4.76 ENST00000369221.2
pancreatic lipase
chr1_-_11847772 4.64 ENST00000376480.7
ENST00000610706.1
natriuretic peptide A
chr12_-_14951106 4.46 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr6_-_84227634 4.42 ENST00000617909.1
ENST00000403245.8
centrosomal protein 162
chr6_-_84227596 4.40 ENST00000257766.8
centrosomal protein 162
chr5_-_39270623 4.26 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr2_+_218382265 4.24 ENST00000233202.11
solute carrier family 11 member 1
chr8_+_102551583 4.17 ENST00000285402.4
outer dense fiber of sperm tails 1
chr11_+_112961480 4.12 ENST00000621850.4
neural cell adhesion molecule 1
chr11_-_125592448 3.97 ENST00000648911.1
fasciculation and elongation protein zeta 1
chr19_-_50025936 3.97 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr3_-_187745460 3.85 ENST00000406870.7
BCL6 transcription repressor
chr1_-_205321737 3.79 ENST00000367157.6
NUAK family kinase 2
chr11_+_17734732 3.70 ENST00000379472.4
ENST00000675775.1
ENST00000265969.8
ENST00000640318.2
ENST00000639325.2
potassium voltage-gated channel subfamily C member 1
chr19_+_859654 3.68 ENST00000592860.2
ENST00000327726.11
complement factor D
chr8_-_27600000 3.68 ENST00000521770.1
clusterin
chr6_-_111873421 3.65 ENST00000368678.8
ENST00000523238.5
ENST00000354650.7
FYN proto-oncogene, Src family tyrosine kinase
chr7_+_74209386 3.64 ENST00000344995.9
linker for activation of T cells family member 2
chr10_+_92691897 3.60 ENST00000492654.3
hematopoietically expressed homeobox
chr3_-_49429304 3.57 ENST00000636166.1
ENST00000273598.8
ENST00000436744.2
novel protein
nicolin 1
chr20_+_45881218 3.55 ENST00000372523.1
zinc finger SWIM-type containing 1
chr12_+_14419136 3.54 ENST00000545769.1
ENST00000428217.6
ENST00000396279.2
ENST00000542514.5
ENST00000536279.1
activating transcription factor 7 interacting protein
chr6_+_131573219 3.51 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr17_-_8163522 3.49 ENST00000404970.3
vesicle associated membrane protein 2
chr5_+_177426701 3.47 ENST00000507633.5
ENST00000393576.7
ENST00000355958.9
ENST00000528793.5
ENST00000512684.1
G protein-coupled receptor kinase 6
chr10_+_92691813 3.44 ENST00000472590.6
hematopoietically expressed homeobox
chr10_+_133237849 3.40 ENST00000325980.10
VENT homeobox
chr20_+_2536573 3.34 ENST00000358864.2
transmembrane channel like 2
chr11_-_114400417 3.33 ENST00000325636.8
ENST00000623205.2
chromosome 11 open reading frame 71
chr11_+_112961247 3.33 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
neural cell adhesion molecule 1
chr6_+_142147162 3.28 ENST00000452973.6
ENST00000620996.4
ENST00000367621.1
ENST00000367630.9
vesicle trafficking 1
chr13_-_40666600 3.27 ENST00000379561.6
forkhead box O1
chr17_-_42745025 3.25 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr11_-_236326 3.23 ENST00000525237.1
ENST00000382743.9
ENST00000532956.5
ENST00000525319.5
ENST00000524564.5
sirtuin 3
chr14_-_81221231 3.19 ENST00000434192.2
general transcription factor IIA subunit 1
chr12_+_57460127 3.17 ENST00000532291.5
ENST00000543426.5
ENST00000546141.5
GLI family zinc finger 1
chr14_-_106507476 3.12 ENST00000390621.3
immunoglobulin heavy variable 1-45
chr7_+_27242796 3.09 ENST00000496902.7
even-skipped homeobox 1
chr22_+_40045451 3.09 ENST00000402203.5
trinucleotide repeat containing adaptor 6B
chr1_-_156816841 3.08 ENST00000368199.8
ENST00000392306.2
SH2 domain containing 2A
chr16_-_75207152 3.06 ENST00000303037.13
chymotrypsinogen B2
chr7_+_143316105 3.06 ENST00000343257.7
ENST00000650516.1
chloride voltage-gated channel 1
chr17_-_78717018 3.05 ENST00000585509.5
cytohesin 1
chr19_-_13102848 2.99 ENST00000264824.5
LYL1 basic helix-loop-helix family member
chr12_+_31959406 2.96 ENST00000540924.5
ENST00000312561.9
retroelement silencing factor 1
chr6_-_13487593 2.93 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr6_+_42929430 2.89 ENST00000372836.5
canopy FGF signaling regulator 3
chr9_-_93955347 2.88 ENST00000253968.11
BARX homeobox 1
chr8_+_2045037 2.87 ENST00000262113.9
myomesin 2
chr17_-_42181116 2.87 ENST00000264661.4
potassium voltage-gated channel subfamily H member 4
chr19_+_13151975 2.83 ENST00000588173.1
immediate early response 2
chr12_+_66189208 2.80 ENST00000261233.9
interleukin 1 receptor associated kinase 3
chr3_+_111292719 2.80 ENST00000460744.1
CD96 molecule
chr2_-_72825982 2.75 ENST00000634650.1
ENST00000272427.11
ENST00000410104.1
exocyst complex component 6B
chr1_+_77779618 2.75 ENST00000370791.7
ENST00000443751.3
ENST00000645756.1
ENST00000643390.1
ENST00000642959.1
mitoguardin 1
chr16_+_75647757 2.75 ENST00000300086.5
ENST00000653858.1
TERF2 interacting protein
chr19_-_15418979 2.75 ENST00000397410.10
ENST00000596195.5
ENST00000595067.1
ENST00000595465.6
ENST00000680649.1
ENST00000679638.1
ENST00000600247.5
A-kinase anchoring protein 8 like
chrX_+_37780049 2.72 ENST00000378588.5
cytochrome b-245 beta chain
chr1_-_156816738 2.71 ENST00000368198.7
SH2 domain containing 2A
chr17_-_42181081 2.71 ENST00000607371.5
potassium voltage-gated channel subfamily H member 4
chr6_+_391743 2.69 ENST00000380956.9
interferon regulatory factor 4
chr14_-_24634266 2.66 ENST00000382540.5
granzyme B
chr13_+_30713477 2.65 ENST00000617770.4
arachidonate 5-lipoxygenase activating protein
chr12_+_57459782 2.64 ENST00000228682.7
GLI family zinc finger 1
chr7_-_6272639 2.63 ENST00000396741.3
cytohesin 3
chr14_-_24634160 2.63 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr8_+_737595 2.61 ENST00000637795.2
DLG associated protein 2
chr6_-_32192845 2.60 ENST00000487761.5
G protein signaling modulator 3
chr11_+_28108248 2.57 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
methyltransferase like 15
chr19_-_54360949 2.54 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr1_+_150926336 2.54 ENST00000271640.9
ENST00000448029.5
ENST00000368962.6
ENST00000534805.5
ENST00000368969.8
ENST00000368963.5
ENST00000498193.5
SET domain bifurcated histone lysine methyltransferase 1
chr1_+_32251239 2.53 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK proto-oncogene, Src family tyrosine kinase
chr14_+_24114627 2.53 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chrX_+_16786421 2.51 ENST00000398155.4
ENST00000380122.10
taxilin gamma
chr12_-_44875647 2.51 ENST00000395487.6
neural EGFL like 2
chr21_-_14546351 2.50 ENST00000619120.4
SAM domain, SH3 domain and nuclear localization signals 1
chr13_+_53028806 2.49 ENST00000219022.3
olfactomedin 4
chr1_+_91952162 2.48 ENST00000402388.1
ENST00000680541.1
bromodomain testis associated
chr16_-_67931859 2.45 ENST00000574481.6
ENST00000571044.5
ENST00000571605.1
chymotrypsin like
chr2_+_60881553 2.44 ENST00000394479.4
REL proto-oncogene, NF-kB subunit
chr17_-_78360066 2.44 ENST00000587578.1
ENST00000330871.3
suppressor of cytokine signaling 3
chr22_+_39946812 2.43 ENST00000407075.3
GRB2 related adaptor protein 2
chr3_-_57693045 2.43 ENST00000311128.10
DENN domain containing 6A
chr2_-_24328113 2.42 ENST00000622089.4
intersectin 2
chr22_+_31753867 2.42 ENST00000535622.6
ENST00000645693.1
ENST00000642974.1
ENST00000645711.1
ENST00000644331.1
ENST00000645560.1
ENST00000437411.6
ENST00000433147.2
ENST00000646755.1
ENST00000382112.8
ENST00000647438.1
ENST00000400248.7
ENST00000456178.6
ENST00000646969.1
ENST00000642696.1
ENST00000647343.1
ENST00000400242.8
ENST00000651528.2
ENST00000645015.1
ENST00000645564.1
ENST00000646465.1
ENST00000400249.7
DEP domain containing 5, GATOR1 subcomplex subunit
chr19_-_54364983 2.40 ENST00000434277.6
leukocyte associated immunoglobulin like receptor 1
chr1_+_172659095 2.38 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr3_-_61251376 2.38 ENST00000476844.5
ENST00000488467.5
ENST00000492590.6
ENST00000468189.5
fragile histidine triad diadenosine triphosphatase
chr15_+_24954912 2.38 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr17_-_40565459 2.38 ENST00000578085.1
ENST00000246657.2
C-C motif chemokine receptor 7
chr2_+_90021567 2.35 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr12_+_66189254 2.30 ENST00000457197.2
interleukin 1 receptor associated kinase 3
chr5_+_35856883 2.30 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr3_+_138010143 2.29 ENST00000183605.10
claudin 18
chr4_-_89836213 2.26 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr19_-_54364863 2.25 ENST00000348231.8
leukocyte associated immunoglobulin like receptor 1
chr19_-_51372686 2.24 ENST00000595217.1
natural killer cell granule protein 7
chr1_+_50048014 2.24 ENST00000448907.7
ELAV like RNA binding protein 4
chr19_-_54364908 2.23 ENST00000391742.7
leukocyte associated immunoglobulin like receptor 1
chr9_+_131502789 2.23 ENST00000372228.9
ENST00000341012.13
ENST00000677216.1
ENST00000676640.1
ENST00000441334.5
ENST00000402686.8
ENST00000677029.1
ENST00000676915.1
ENST00000676803.1
ENST00000677293.1
ENST00000678303.1
ENST00000677626.1
ENST00000372220.5
ENST00000683229.1
ENST00000418774.6
ENST00000430619.2
ENST00000448212.5
ENST00000679221.1
ENST00000678785.1
protein O-mannosyltransferase 1
chr8_-_65842051 2.17 ENST00000401827.8
phosphodiesterase 7A
chr6_-_46491956 2.14 ENST00000306764.11
regulator of calcineurin 2
chr2_+_60881515 2.11 ENST00000295025.12
REL proto-oncogene, NF-kB subunit
chr21_-_14546297 2.08 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr17_-_42276341 2.03 ENST00000293328.8
signal transducer and activator of transcription 5B
chr17_-_37609361 1.99 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr5_-_34043205 1.96 ENST00000382065.8
ENST00000231338.7
C1q and TNF related 3
chr17_-_10026265 1.95 ENST00000437099.6
ENST00000396115.6
growth arrest specific 7
chr19_-_344786 1.94 ENST00000264819.7
MIER family member 2
chr1_-_110606009 1.94 ENST00000640774.2
ENST00000638616.2
potassium voltage-gated channel subfamily A member 2
chr2_-_79086847 1.93 ENST00000454188.5
regenerating family member 1 beta
chr1_+_184386978 1.91 ENST00000235307.7
chromosome 1 open reading frame 21
chr17_-_8376658 1.90 ENST00000643221.1
ENST00000647210.1
ENST00000649935.1
ENST00000396267.3
KRAB-A domain containing 2
chr12_-_91182652 1.90 ENST00000552145.5
ENST00000546745.5
decorin
chr5_+_66828762 1.87 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr9_-_130043154 1.86 ENST00000355681.3
ENST00000446176.7
ENST00000443566.6
ENST00000420781.5
formin binding protein 1
chr2_+_79025709 1.86 ENST00000409471.1
regenerating family member 3 gamma
chr6_-_159745186 1.85 ENST00000537657.5
superoxide dismutase 2
chr16_+_77199408 1.85 ENST00000378644.5
synaptonemal complex central element protein 1 like
chr17_+_27631148 1.85 ENST00000313648.10
ENST00000395473.7
ENST00000577392.5
ENST00000584661.5
galectin 9
chr9_+_121286586 1.85 ENST00000545652.6
gelsolin
chr7_-_6272575 1.84 ENST00000350796.8
cytohesin 3
chrX_+_70423031 1.83 ENST00000453994.6
ENST00000538649.5
ENST00000536730.5
glycerophosphodiester phosphodiesterase domain containing 2
chr14_+_20999255 1.82 ENST00000554422.5
ENST00000298681.5
solute carrier family 39 member 2
chr14_-_24114913 1.82 ENST00000561028.6
ENST00000558280.1
neural retina leucine zipper
chr2_-_151971750 1.78 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chr20_+_44966478 1.77 ENST00000499879.6
ENST00000372806.8
ENST00000372801.5
serine/threonine kinase 4
chr17_+_48107549 1.75 ENST00000580219.5
ENST00000452859.6
ENST00000393405.6
sorting nexin 11
chr3_+_121835197 1.74 ENST00000273668.7
ENST00000451944.2
ELL associated factor 2
chr2_+_79025678 1.72 ENST00000393897.6
regenerating family member 3 gamma
chr7_+_5880798 1.71 ENST00000242104.6
oncomodulin
chr1_+_160343375 1.70 ENST00000294785.10
ENST00000421914.5
ENST00000438008.5
nicastrin
chr5_-_138178599 1.69 ENST00000454473.5
ENST00000418329.5
ENST00000254900.10
ENST00000230901.9
ENST00000402931.5
ENST00000411594.6
ENST00000430331.1
bromodomain containing 8
chr17_-_39152571 1.69 ENST00000415163.5
ENST00000441877.5
ENST00000444911.6
plexin domain containing 1
chr16_-_88651015 1.66 ENST00000568278.1
ENST00000569359.5
ENST00000567174.5
ENST00000261623.8
cytochrome b-245 alpha chain
chr6_-_52840843 1.65 ENST00000370989.6
glutathione S-transferase alpha 5
chrX_-_101291325 1.65 ENST00000356784.2
TATA-box binding protein associated factor 7 like
chr5_+_140107777 1.65 ENST00000505703.2
ENST00000651386.1
purine rich element binding protein A
chrX_+_70423301 1.64 ENST00000374382.4
glycerophosphodiester phosphodiesterase domain containing 2
chr4_-_89835617 1.64 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr2_+_79025696 1.63 ENST00000272324.10
regenerating family member 3 gamma
chr1_-_18902520 1.63 ENST00000538839.5
ENST00000290597.9
ENST00000375341.8
aldehyde dehydrogenase 4 family member A1
chr10_+_123008966 1.62 ENST00000368869.8
ENST00000358776.7
acyl-CoA dehydrogenase short/branched chain
chr4_+_48830998 1.61 ENST00000509122.5
ENST00000509664.5
ENST00000505922.6
ENST00000514981.5
ENST00000511662.5
ENST00000508996.5
ENST00000507210.5
ENST00000396448.6
ENST00000512236.5
ENST00000509164.5
ENST00000511102.5
ENST00000381473.7
ENST00000264312.12
ENST00000444354.6
ENST00000509963.5
ENST00000509246.5
OCIA domain containing 1
chr12_+_64780465 1.61 ENST00000542120.6
TBC1 domain family member 30
chr22_-_38302990 1.60 ENST00000612795.2
ENST00000451964.5
casein kinase 1 epsilon
chr2_-_218166951 1.60 ENST00000295683.3
C-X-C motif chemokine receptor 1
chr19_+_49119531 1.60 ENST00000334186.9
PTPRF interacting protein alpha 3
chr11_+_72135718 1.60 ENST00000611028.3
ENST00000546166.1
ENST00000442948.3
folate receptor gamma
chr14_+_75069632 1.59 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
zinc finger C2HC-type containing 1C
chr10_-_118595637 1.58 ENST00000239032.4
prolactin releasing hormone receptor
chr6_-_142147122 1.57 ENST00000258042.2
neuromedin B receptor
chr10_+_112375196 1.55 ENST00000393081.6
acyl-CoA synthetase long chain family member 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 27.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
2.9 8.7 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
2.7 11.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
2.6 23.3 GO:0001661 conditioned taste aversion(GO:0001661)
2.3 7.0 GO:0061011 hepatic duct development(GO:0061011) hepatoblast differentiation(GO:0061017)
1.9 11.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.9 7.8 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
1.9 5.8 GO:0060032 notochord regression(GO:0060032)
1.8 5.4 GO:1900195 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
1.7 5.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
1.7 8.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.5 12.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.5 9.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.5 4.5 GO:0071461 cellular response to redox state(GO:0071461)
1.5 4.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
1.5 4.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.3 5.3 GO:0002357 defense response to tumor cell(GO:0002357)
1.2 3.7 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
1.2 6.0 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
1.1 3.3 GO:0060005 vestibular reflex(GO:0060005)
1.1 10.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.0 8.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
1.0 3.9 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.9 1.8 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.9 2.7 GO:0045082 interleukin-13 biosynthetic process(GO:0042231) positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.9 25.8 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.8 2.5 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.8 3.3 GO:1902617 response to fluoride(GO:1902617)
0.8 2.4 GO:2000523 dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.8 6.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.7 3.7 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 2.8 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.7 5.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6 3.9 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.6 5.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.6 2.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.6 2.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.6 1.7 GO:0019858 cytosine metabolic process(GO:0019858)
0.6 1.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.5 1.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.5 1.6 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.5 8.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.5 2.7 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.5 1.4 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.5 1.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.4 0.9 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.4 3.5 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of histamine secretion by mast cell(GO:1903593)
0.4 0.4 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.4 8.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 1.2 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.4 2.7 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.4 1.9 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.4 1.8 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.4 1.5 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) positive regulation of chondrocyte proliferation(GO:1902732)
0.4 3.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.4 1.8 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.4 2.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4 3.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.3 1.4 GO:0048627 myoblast development(GO:0048627)
0.3 2.0 GO:0048541 positive regulation of gamma-delta T cell differentiation(GO:0045588) mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
0.3 4.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.3 2.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.3 0.9 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.3 0.6 GO:0048859 formation of anatomical boundary(GO:0048859)
0.3 0.9 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.3 1.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3 0.9 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.3 1.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.3 3.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.3 3.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.3 8.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 0.9 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.3 2.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.3 0.9 GO:0014805 smooth muscle adaptation(GO:0014805)
0.3 4.8 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.3 1.7 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.3 1.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 2.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 3.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.3 0.8 GO:0071288 cellular response to mercury ion(GO:0071288)
0.3 1.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 3.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 2.3 GO:0033089 negative regulation of T cell mediated cytotoxicity(GO:0001915) positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 3.0 GO:0001955 blood vessel maturation(GO:0001955)
0.2 2.5 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.2 1.7 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 2.0 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.2 7.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 2.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 1.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.2 0.7 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.2 3.1 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 3.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 2.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 2.7 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.2 1.0 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.2 0.4 GO:0035962 response to interleukin-13(GO:0035962)
0.2 3.5 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.0 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 2.6 GO:2001300 lipoxin metabolic process(GO:2001300)
0.2 0.6 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.2 5.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.2 1.9 GO:0021633 optic nerve structural organization(GO:0021633)
0.2 2.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 1.5 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.2 5.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 2.3 GO:0015871 choline transport(GO:0015871)
0.2 0.4 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.2 2.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 3.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.3 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 0.5 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 0.6 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 4.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 1.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 0.5 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.2 2.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 2.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 1.0 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 1.3 GO:0009299 mRNA transcription(GO:0009299)
0.1 0.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.8 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.8 GO:0042048 olfactory behavior(GO:0042048) sensory processing(GO:0050893)
0.1 1.9 GO:0015074 DNA integration(GO:0015074)
0.1 1.3 GO:0097647 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.9 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 5.0 GO:0030220 platelet formation(GO:0030220)
0.1 4.6 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 4.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 1.6 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 3.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 1.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.5 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 2.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 2.3 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 1.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 6.9 GO:0007602 phototransduction(GO:0007602)
0.1 0.5 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.1 1.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.0 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.5 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 2.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.7 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 12.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 0.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.6 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 1.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.5 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 6.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 2.6 GO:0048536 spleen development(GO:0048536)
0.1 1.9 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 7.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 1.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.1 0.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 2.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.8 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 3.3 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 2.2 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 5.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 3.7 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 5.3 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 1.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 3.2 GO:0021766 hippocampus development(GO:0021766)
0.0 2.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 2.2 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 16.7 GO:0002250 adaptive immune response(GO:0002250)
0.0 1.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 2.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 1.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.6 GO:0015884 folic acid transport(GO:0015884)
0.0 2.0 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.5 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.1 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.4 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.2 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 1.5 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.0 0.9 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 1.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.0 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.9 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 3.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 1.0 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 1.1 GO:0035456 response to interferon-beta(GO:0035456)
0.0 15.8 GO:0006954 inflammatory response(GO:0006954)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 1.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.7 GO:0021510 spinal cord development(GO:0021510)
0.0 1.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 1.6 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.6 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 1.3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 4.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 1.7 GO:0002262 myeloid cell homeostasis(GO:0002262)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.5 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.2 GO:0021591 ventricular system development(GO:0021591)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.8 GO:0030574 collagen catabolic process(GO:0030574)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 23.3 GO:0035976 AP1 complex(GO:0035976)
1.5 8.8 GO:0005879 axonemal microtubule(GO:0005879)
1.1 3.3 GO:0032426 stereocilium tip(GO:0032426)
0.9 2.7 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.9 3.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.6 5.4 GO:0072687 meiotic spindle(GO:0072687)
0.5 5.3 GO:0044194 cytolytic granule(GO:0044194)
0.5 4.2 GO:0001520 outer dense fiber(GO:0001520)
0.5 1.4 GO:0035517 PR-DUB complex(GO:0035517)
0.4 10.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 11.9 GO:0032982 myosin filament(GO:0032982)
0.4 1.7 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.4 15.3 GO:0042629 mast cell granule(GO:0042629)
0.4 2.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 3.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 4.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 2.4 GO:1990130 Iml1 complex(GO:1990130)
0.3 2.7 GO:0070187 telosome(GO:0070187)
0.3 3.1 GO:0044294 dendritic growth cone(GO:0044294)
0.3 0.9 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 0.9 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 4.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 2.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.3 5.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 1.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 3.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 1.5 GO:0005927 muscle tendon junction(GO:0005927) cuticular plate(GO:0032437)
0.2 20.9 GO:0035580 specific granule lumen(GO:0035580)
0.2 3.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 1.3 GO:0031501 mannosyltransferase complex(GO:0031501)
0.2 2.7 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 0.6 GO:0044292 dendrite terminus(GO:0044292)
0.2 2.6 GO:0005883 neurofilament(GO:0005883)
0.2 2.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 2.8 GO:0000145 exocyst(GO:0000145)
0.2 0.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 5.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 12.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 15.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 1.4 GO:0035253 ciliary rootlet(GO:0035253)
0.1 14.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 8.0 GO:0001772 immunological synapse(GO:0001772)
0.1 1.8 GO:0030478 actin cap(GO:0030478)
0.1 3.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 3.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 0.8 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 1.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.1 1.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 2.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 11.0 GO:0072562 blood microparticle(GO:0072562)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 4.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 8.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 5.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 8.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.6 GO:0035579 specific granule membrane(GO:0035579)
0.0 3.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 4.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 2.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 4.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 6.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0031904 endosome lumen(GO:0031904)
0.0 0.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 2.4 GO:0005814 centriole(GO:0005814)
0.0 3.3 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.2 GO:0031672 A band(GO:0031672)
0.0 1.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)
0.0 12.2 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 25.4 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
6.9 27.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
2.8 11.3 GO:0032184 SUMO polymer binding(GO:0032184)
2.7 8.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.8 25.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
1.8 9.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.8 5.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
1.4 8.6 GO:0003796 lysozyme activity(GO:0003796)
1.2 6.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.9 6.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.7 7.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.7 3.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.7 6.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.6 3.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.6 2.6 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.6 12.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.6 3.5 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.6 4.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.6 3.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 11.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.5 1.6 GO:0019959 interleukin-8 binding(GO:0019959)
0.4 1.3 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.4 26.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 1.3 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.4 4.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.4 5.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 10.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.4 1.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.4 7.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 2.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.3 1.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 11.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 1.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.3 1.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 0.9 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.3 0.8 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.3 7.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 2.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.2 1.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 5.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 3.9 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 8.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 2.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 3.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 1.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 4.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 1.3 GO:0039552 RIG-I binding(GO:0039552)
0.2 1.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 2.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.2 4.6 GO:0051787 misfolded protein binding(GO:0051787)
0.2 4.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 3.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 0.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 3.2 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.2 1.9 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 3.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 0.8 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 3.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 2.2 GO:0031419 cobalamin binding(GO:0031419)
0.2 2.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 1.1 GO:0005497 androgen binding(GO:0005497)
0.2 0.6 GO:0005148 prolactin receptor binding(GO:0005148)
0.2 2.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 3.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 7.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 3.8 GO:0022829 wide pore channel activity(GO:0022829)
0.1 0.6 GO:0002046 opsin binding(GO:0002046)
0.1 1.0 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 5.3 GO:0042605 peptide antigen binding(GO:0042605)
0.1 10.0 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 0.4 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.1 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 1.8 GO:0045159 myosin II binding(GO:0045159)
0.1 0.7 GO:0005119 smoothened binding(GO:0005119)
0.1 1.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 36.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 4.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.4 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 10.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 3.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.5 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 3.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.7 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.1 0.9 GO:0043184 C-X3-C chemokine binding(GO:0019960) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 4.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 6.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 1.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 11.2 GO:0003823 antigen binding(GO:0003823)
0.1 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 8.4 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.4 GO:0051400 BH domain binding(GO:0051400)
0.1 0.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 5.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.3 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 2.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 15.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 1.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.4 GO:0019894 kinesin binding(GO:0019894)
0.0 1.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 3.5 GO:0051117 ATPase binding(GO:0051117)
0.0 4.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.1 GO:0005254 chloride channel activity(GO:0005254)
0.0 4.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 24.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 13.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 10.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 12.3 PID AURORA A PATHWAY Aurora A signaling
0.2 2.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 9.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 14.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 17.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 2.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 2.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 11.9 PID FGF PATHWAY FGF signaling pathway
0.1 1.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 6.0 PID IL1 PATHWAY IL1-mediated signaling events
0.1 10.0 PID AP1 PATHWAY AP-1 transcription factor network
0.1 8.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 3.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 8.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.9 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.9 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 15.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.9 PID FOXO PATHWAY FoxO family signaling
0.1 6.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 2.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 8.7 PID CMYB PATHWAY C-MYB transcription factor network
0.1 8.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 2.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 2.2 PID ATM PATHWAY ATM pathway
0.1 2.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 2.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 25.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.7 11.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.6 28.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.4 7.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.3 2.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.3 5.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 6.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 5.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 20.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 12.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 13.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 3.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 3.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 6.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 3.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 4.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 6.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 8.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 3.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 2.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 3.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.8 REACTOME OPSINS Genes involved in Opsins
0.1 1.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.7 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.1 0.9 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 1.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 3.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 4.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 3.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway