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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TBX3

Z-value: 5.66

Motif logo

Transcription factors associated with TBX3

Gene Symbol Gene ID Gene Info
ENSG00000135111.16 TBX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX3hg38_v1_chr12_-_114684151_114684221,
hg38_v1_chr12_-_114683590_114683652
0.421.1e-10Click!

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_88857582 18.84 ENST00000390237.2
immunoglobulin kappa constant
chrX_+_16719595 17.80 ENST00000380155.4
synapse associated protein 1
chr22_+_22895368 17.73 ENST00000390321.2
immunoglobulin lambda constant 1
chr6_+_33080445 13.19 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr2_-_88992903 13.00 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr16_+_58249910 12.97 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr19_-_36152427 11.88 ENST00000589154.1
ENST00000292907.8
cytochrome c oxidase subunit 7A1
chr16_+_55479188 11.23 ENST00000219070.9
matrix metallopeptidase 2
chr14_-_20802402 9.84 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr14_-_20802836 9.42 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr16_+_72063226 9.14 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
haptoglobin-related protein
chr12_+_123671105 9.10 ENST00000680574.1
ENST00000426174.6
ENST00000679504.1
ENST00000303372.7
tectonic family member 2
chr1_+_35930712 7.46 ENST00000324350.9
argonaute RISC catalytic component 3
chrX_-_66040072 7.36 ENST00000374737.9
V-set and immunoglobulin domain containing 4
chr22_+_24603147 7.30 ENST00000412658.5
ENST00000445029.5
ENST00000400382.6
ENST00000419133.5
ENST00000438643.6
ENST00000452551.5
ENST00000412898.5
ENST00000400380.5
ENST00000455483.5
ENST00000430289.5
gamma-glutamyltransferase 1
chr5_+_55024250 7.07 ENST00000231009.3
granzyme K
chr2_-_89010515 6.92 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr8_+_132919403 6.79 ENST00000519178.5
thyroglobulin
chr19_-_51027662 6.71 ENST00000594768.5
kallikrein related peptidase 11
chr19_-_51028015 6.68 ENST00000319720.11
kallikrein related peptidase 11
chr15_+_79311137 6.62 ENST00000424155.6
ENST00000536821.5
transmembrane p24 trafficking protein 3
chr2_+_66439294 6.59 ENST00000495021.6
Meis homeobox 1
chrX_-_66040057 6.57 ENST00000412866.2
V-set and immunoglobulin domain containing 4
chr14_-_106411021 6.50 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr2_-_216695540 6.29 ENST00000233813.5
insulin like growth factor binding protein 5
chr16_+_72054477 6.17 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr7_+_150567382 6.16 ENST00000255945.4
ENST00000479232.1
GTPase, IMAP family member 4
chr1_-_11805294 5.92 ENST00000413656.5
ENST00000376592.6
ENST00000376585.6
methylenetetrahydrofolate reductase
chr11_-_10568571 5.65 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr12_+_51424802 5.57 ENST00000453097.7
solute carrier family 4 member 8
chr5_+_35617838 5.55 ENST00000282469.10
ENST00000509059.5
ENST00000637569.1
ENST00000356031.8
ENST00000510777.5
sperm flagellar 2
chr11_-_10568650 5.51 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr6_-_169250825 5.37 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr6_+_121435595 5.24 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr6_+_29585121 5.19 ENST00000641840.1
olfactory receptor family 2 subfamily H member 2
chr8_+_78666056 5.16 ENST00000263849.9
zinc finger C2HC-type containing 1A
chr19_+_53395125 5.11 ENST00000396408.8
ENST00000505866.1
ENST00000594030.2
zinc finger protein 765
chr12_+_12070932 4.98 ENST00000308721.9
BCL2 like 14
chr14_+_73950252 4.97 ENST00000629426.2
coenzyme Q6, monooxygenase
chr9_-_98192614 4.93 ENST00000375077.5
coronin 2A
chr7_+_65873091 4.92 ENST00000648187.1
vitamin K epoxide reductase complex subunit 1 like 1
chr1_-_212035513 4.90 ENST00000366992.7
ENST00000366993.7
ENST00000440600.6
ENST00000366994.8
integrator complex subunit 7
chr7_+_65873068 4.89 ENST00000360768.5
vitamin K epoxide reductase complex subunit 1 like 1
chr1_-_183590876 4.51 ENST00000367536.5
neutrophil cytosolic factor 2
chr14_+_73950285 4.36 ENST00000334571.7
ENST00000554920.5
coenzyme Q6, monooxygenase
chr19_+_9185594 4.25 ENST00000344248.4
olfactory receptor family 7 subfamily D member 2
chr22_+_24495242 4.24 ENST00000382760.2
ENST00000326010.10
beta-ureidopropionase 1
chr12_+_133181409 4.18 ENST00000416488.5
ENST00000228289.9
ENST00000541211.6
ENST00000536435.7
ENST00000500625.7
ENST00000539248.6
ENST00000542711.6
ENST00000536899.6
ENST00000542986.6
ENST00000611984.4
ENST00000541975.2
zinc finger protein 268
chr15_-_73368951 4.12 ENST00000261917.4
hyperpolarization activated cyclic nucleotide gated potassium channel 4
chr5_-_39425187 4.10 ENST00000545653.5
DAB adaptor protein 2
chr14_+_73644875 4.07 ENST00000554113.5
ENST00000553645.7
ENST00000555631.6
ENST00000311089.7
ENST00000555919.7
ENST00000554339.5
ENST00000554871.5
dynein axonemal light chain 1
chr12_+_133181529 4.07 ENST00000541009.6
ENST00000592241.5
zinc finger protein 268
chr7_+_150737382 3.99 ENST00000358647.5
GTPase, IMAP family member 5
chr19_-_10569022 3.99 ENST00000335766.2
cyclin dependent kinase inhibitor 2D
chr12_-_88142040 3.96 ENST00000552810.6
ENST00000673058.2
ENST00000675833.1
ENST00000675476.1
ENST00000309041.12
ENST00000675408.1
ENST00000675230.1
ENST00000397838.8
ENST00000552770.3
centrosomal protein 290
chr17_-_42423246 3.92 ENST00000357037.6
caveolae associated protein 1
chr19_-_10568968 3.83 ENST00000393599.3
cyclin dependent kinase inhibitor 2D
chr12_+_109573757 3.76 ENST00000228510.8
ENST00000539696.5
ENST00000392727.7
mevalonate kinase
chr7_+_22727147 3.67 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
interleukin 6
chr2_-_159798043 3.66 ENST00000664982.1
ENST00000259053.6
novel transcript, sense intronic to CD302and LY75-CD302
CD302 molecule
chrX_+_136487940 3.66 ENST00000370648.4
bombesin receptor subtype 3
chr8_-_132111159 3.62 ENST00000673615.1
ENST00000434736.6
HERV-H LTR-associating 1
chr10_-_69416323 3.61 ENST00000619173.4
tachykinin receptor 2
chr14_+_21317535 3.55 ENST00000382933.8
RPGR interacting protein 1
chr11_-_8263858 3.53 ENST00000534484.1
ENST00000335790.8
LIM domain only 1
chr19_-_32869741 3.50 ENST00000590341.5
ENST00000587772.1
ENST00000023064.9
solute carrier family 7 member 9
chr16_+_83899079 3.49 ENST00000262430.6
malonyl-CoA decarboxylase
chr3_+_52420955 3.46 ENST00000465863.1
PHD finger protein 7
chr2_-_159798234 3.45 ENST00000429078.6
ENST00000553424.5
CD302 molecule
chr2_-_24047348 3.43 ENST00000406895.3
WD repeat and coiled coil containing
chrX_-_66639022 3.42 ENST00000374719.8
ectodysplasin A2 receptor
chr2_+_113117889 3.41 ENST00000361779.7
ENST00000259206.9
ENST00000354115.6
interleukin 1 receptor antagonist
chr2_+_90220727 3.40 ENST00000471857.2
immunoglobulin kappa variable 1D-8
chr14_+_20110739 3.35 ENST00000641386.2
ENST00000641633.2
olfactory receptor family 4 subfamily K member 17
chrX_-_66639255 3.33 ENST00000451436.6
ectodysplasin A2 receptor
chr4_+_40193642 3.33 ENST00000617441.4
ENST00000503941.5
ras homolog family member H
chr16_+_33009175 3.31 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr2_-_216694794 3.29 ENST00000449583.1
insulin like growth factor binding protein 5
chr1_+_162632454 3.25 ENST00000367921.8
ENST00000367922.7
discoidin domain receptor tyrosine kinase 2
chr22_+_22720615 3.24 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr4_+_70195719 3.23 ENST00000683306.1
odontogenic, ameloblast associated
chr15_-_80252205 3.21 ENST00000560778.3
cortexin domain containing 1
chr2_-_24047375 3.21 ENST00000295148.9
WD repeat and coiled coil containing
chr17_-_1516699 3.20 ENST00000320345.10
ENST00000406424.8
inositol polyphosphate-5-phosphatase K
chr5_-_39424966 3.19 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr19_-_51027954 3.15 ENST00000391804.7
kallikrein related peptidase 11
chr7_-_150978284 3.09 ENST00000262186.10
potassium voltage-gated channel subfamily H member 2
chrX_+_136205982 2.99 ENST00000628568.1
four and a half LIM domains 1
chr5_-_160312756 2.93 ENST00000644313.1
cyclin J like
chr15_-_42920798 2.93 ENST00000622375.4
ENST00000567840.5
tau tubulin kinase 2
chr20_-_1491407 2.88 ENST00000359801.8
signal regulatory protein beta 2
chr3_+_189631373 2.83 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr4_+_154563003 2.79 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr17_-_45490696 2.74 ENST00000430334.8
ENST00000584420.1
ENST00000589780.5
pleckstrin homology and RUN domain containing M1
chr5_+_141373878 2.73 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr10_-_69416912 2.73 ENST00000373306.5
tachykinin receptor 2
chr17_-_1516621 2.62 ENST00000574561.1
inositol polyphosphate-5-phosphatase K
chr13_-_46105009 2.62 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
carboxypeptidase B2
chr19_+_42220283 2.59 ENST00000301215.8
ENST00000597945.1
zinc finger protein 526
chr15_-_42920638 2.58 ENST00000566931.1
ENST00000564431.5
ENST00000567274.5
ENST00000267890.11
tau tubulin kinase 2
chr11_-_61161414 2.54 ENST00000301765.10
VPS37C subunit of ESCRT-I
chr22_+_22811737 2.53 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr22_-_21227637 2.52 ENST00000401924.5
gamma-glutamyltransferase 2
chr4_-_79326008 2.50 ENST00000286794.5
N-alpha-acetyltransferase 11, NatA catalytic subunit
chr16_+_142725 2.49 ENST00000652335.1
hemoglobin subunit zeta
chr9_+_35490103 2.47 ENST00000361226.8
RUN and SH3 domain containing 2
chr14_-_73950393 2.46 ENST00000651776.1
FAM161 centrosomal protein B
chr7_+_80646436 2.43 ENST00000419819.2
CD36 molecule
chr19_+_54816468 2.40 ENST00000391728.8
ENST00000326542.11
ENST00000358178.4
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
chr7_+_150567347 2.38 ENST00000461940.5
GTPase, IMAP family member 4
chr7_+_144069811 2.36 ENST00000641663.1
olfactory receptor family 2 subfamily A member 25
chr2_+_32277883 2.35 ENST00000238831.9
Yip1 domain family member 4
chr6_-_46735693 2.33 ENST00000537365.1
phospholipase A2 group VII
chr13_+_20567131 2.33 ENST00000319980.10
ENST00000351808.10
ENST00000389373.3
intraflagellar transport 88
chr19_-_5567831 2.31 ENST00000587632.1
ENST00000646160.1
TINCR ubiquitin domain containing
chr16_+_3012915 2.31 ENST00000445369.3
claudin 9
chr12_+_10929229 2.30 ENST00000381847.7
ENST00000396400.4
proline rich protein HaeIII subfamily 2
chr19_-_42427379 2.30 ENST00000244289.9
lipase E, hormone sensitive type
chr11_+_111912725 2.29 ENST00000304298.4
heat shock protein family B (small) member 2
chr5_-_175444132 2.28 ENST00000393752.3
dopamine receptor D1
chrX_-_132489015 2.25 ENST00000421707.1
ENST00000370853.8
muscleblind like splicing regulator 3
chr19_+_1077394 2.23 ENST00000590577.2
Rho GTPase activating protein 45
chr6_-_11382247 2.22 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr8_+_97887903 2.16 ENST00000520016.5
matrilin 2
chr14_-_77457554 2.13 ENST00000343765.6
ENST00000327028.8
ENST00000556412.4
ENST00000557466.1
ENST00000448935.6
ENST00000557658.6
ENST00000553888.5
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr19_-_54360949 2.12 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr8_-_71362054 2.08 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr17_-_3104422 2.06 ENST00000641064.1
ENST00000641833.1
olfactory receptor family 1 subfamily D member 2
chr5_+_150661243 1.95 ENST00000517768.6
myozenin 3
chr19_-_51034840 1.95 ENST00000529888.5
kallikrein related peptidase 12
chr14_-_24442765 1.91 ENST00000555365.5
ENST00000399395.8
ENST00000553930.5
short chain dehydrogenase/reductase family 39U member 1
chr3_-_179266971 1.89 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr6_-_110415539 1.87 ENST00000368923.8
ENST00000368924.9
D-aspartate oxidase
chr4_+_25312766 1.86 ENST00000302874.9
ENST00000612982.1
zinc finger CCHC-type containing 4
chr13_+_27919993 1.81 ENST00000381033.5
pancreatic and duodenal homeobox 1
chr1_+_151047699 1.78 ENST00000368926.6
chromosome 1 open reading frame 56
chr3_+_149474688 1.76 ENST00000305354.5
ENST00000465758.1
transmembrane 4 L six family member 4
chr11_-_105023136 1.76 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr1_-_9910169 1.73 ENST00000377263.6
catenin beta interacting protein 1
chr9_+_5231413 1.73 ENST00000239316.4
insulin like 4
chr8_-_71361860 1.67 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chrX_+_66162663 1.64 ENST00000519389.6
hephaestin
chr5_-_138274565 1.61 ENST00000378362.3
GDNF family receptor alpha 3
chr3_+_148730100 1.54 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr6_+_29396555 1.52 ENST00000623183.1
olfactory receptor family 12 subfamily D member 2
chr7_+_143954844 1.45 ENST00000641412.1
olfactory receptor family 2 subfamily F member 1
chr19_-_38878247 1.43 ENST00000591812.2
Ras and Rab interactor like
chr22_+_26621952 1.42 ENST00000354760.4
crystallin beta A4
chr16_+_2026834 1.41 ENST00000424542.7
ENST00000432365.6
SLC9A3 regulator 2
chr2_-_178108339 1.40 ENST00000358450.8
phosphodiesterase 11A
chr12_-_7695752 1.39 ENST00000329913.4
growth differentiation factor 3
chr20_+_8789517 1.34 ENST00000437439.2
phospholipase C beta 1
chr14_-_106360320 1.33 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr21_-_14546351 1.27 ENST00000619120.4
SAM domain, SH3 domain and nuclear localization signals 1
chr3_+_42856021 1.27 ENST00000493193.1
atypical chemokine receptor 2
chr19_-_10380558 1.26 ENST00000524462.5
ENST00000525621.6
ENST00000531836.5
tyrosine kinase 2
chr3_-_61251376 1.24 ENST00000476844.5
ENST00000488467.5
ENST00000492590.6
ENST00000468189.5
fragile histidine triad diadenosine triphosphatase
chr6_-_73225465 1.23 ENST00000370388.4
KH domain containing 1 like
chr1_+_172659095 1.21 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr19_+_39445546 1.15 ENST00000402194.6
ENST00000601515.5
ENST00000432763.7
ENST00000594729.5
SPT5 homolog, DSIF elongation factor subunit
chr19_-_14835162 1.13 ENST00000322301.5
olfactory receptor family 7 subfamily A member 5
chr12_-_99984227 1.13 ENST00000547776.6
ENST00000547010.5
ankyrin repeat and sterile alpha motif domain containing 1B
chr19_-_7702139 1.12 ENST00000346664.9
Fc fragment of IgE receptor II
chr11_-_119018328 1.12 ENST00000527673.2
ribosomal protein S25
chr17_+_47209035 1.11 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr9_+_131502789 1.11 ENST00000372228.9
ENST00000341012.13
ENST00000677216.1
ENST00000676640.1
ENST00000441334.5
ENST00000402686.8
ENST00000677029.1
ENST00000676915.1
ENST00000676803.1
ENST00000677293.1
ENST00000678303.1
ENST00000677626.1
ENST00000372220.5
ENST00000683229.1
ENST00000418774.6
ENST00000430619.2
ENST00000448212.5
ENST00000679221.1
ENST00000678785.1
protein O-mannosyltransferase 1
chr1_+_196888014 1.08 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chrX_-_71618455 1.07 ENST00000373691.4
ENST00000373693.4
C-X-C motif chemokine receptor 3
chr19_-_55180104 1.07 ENST00000537500.5
synaptotagmin 5
chrX_+_22136552 1.07 ENST00000682888.1
ENST00000684356.1
phosphate regulating endopeptidase homolog X-linked
chr5_-_138274610 1.06 ENST00000274721.8
GDNF family receptor alpha 3
chr4_-_5019437 1.04 ENST00000506508.1
ENST00000509419.1
ENST00000307746.9
cytokine like 1
chr8_+_22059169 1.03 ENST00000358242.5
dematin actin binding protein
chr19_-_6333603 1.03 ENST00000301452.5
alkaline ceramidase 1
chr19_-_51034892 1.02 ENST00000319590.8
ENST00000250351.4
kallikrein related peptidase 12
chr21_-_14546297 1.00 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr20_+_35772003 0.99 ENST00000374012.8
ENST00000339089.10
ENST00000374000.8
PHD finger protein 20
chr6_+_26087417 0.97 ENST00000357618.10
ENST00000309234.10
homeostatic iron regulator
chr5_-_135954962 0.95 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr11_+_119121559 0.91 ENST00000350777.7
ENST00000529988.5
ENST00000527410.3
histone H4 transcription factor
chr3_-_179259208 0.89 ENST00000485523.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr7_-_135211313 0.86 ENST00000682802.1
ENST00000683848.1
ENST00000354475.5
WD repeat domain 91
chr6_-_32853813 0.81 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr1_-_153113507 0.80 ENST00000468739.2
small proline rich protein 2F
chr15_+_40569290 0.80 ENST00000315616.12
ENST00000559271.1
ENST00000616318.1
RNA pseudouridine synthase domain containing 2
chr14_-_74302910 0.80 ENST00000556971.1
ENST00000356924.9
ATP binding cassette subfamily D member 4
chr11_-_1608463 0.78 ENST00000399685.1
keratin associated protein 5-3
chr9_-_127916978 0.78 ENST00000361444.3
ENST00000335791.10
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr13_+_72782225 0.76 ENST00000615625.1
progesterone immunomodulatory binding factor 1
chr11_+_7485492 0.75 ENST00000534244.1
ENST00000329293.4
olfactomedin like 1
chr19_-_55180010 0.73 ENST00000589172.5
synaptotagmin 5
chr5_+_150660841 0.72 ENST00000297130.4
myozenin 3
chr14_-_73950075 0.67 ENST00000286544.5
FAM161 centrosomal protein B
chr8_+_32646838 0.62 ENST00000651333.1
ENST00000652592.1
neuregulin 1
chrX_+_141896235 0.61 ENST00000409007.1
MAGE family member C3
chr9_+_87497222 0.61 ENST00000358077.9
death associated protein kinase 1
chr20_+_142573 0.59 ENST00000382398.4
defensin beta 126
chr19_-_7702124 0.57 ENST00000597921.6
Fc fragment of IgE receptor II
chr1_-_51345105 0.56 ENST00000413473.6
ENST00000401051.7
ENST00000527205.1
tetratricopeptide repeat domain 39A
chr17_-_7114240 0.53 ENST00000446679.6
asialoglycoprotein receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
2.7 8.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
2.4 7.3 GO:0035026 leading edge cell differentiation(GO:0035026)
2.2 11.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
2.1 6.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.9 5.8 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
1.7 8.6 GO:0035106 operant conditioning(GO:0035106)
1.4 4.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
1.3 5.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.3 3.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
1.2 7.5 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
1.0 3.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
1.0 5.9 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
1.0 6.8 GO:0015705 iodide transport(GO:0015705)
0.9 3.7 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.9 7.3 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.8 2.5 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.8 9.8 GO:0042373 vitamin K metabolic process(GO:0042373)
0.8 7.8 GO:0048102 autophagic cell death(GO:0048102)
0.7 2.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.7 3.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.7 3.5 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.7 13.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 2.6 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.6 48.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.6 1.9 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.5 3.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.5 6.8 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.5 9.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.5 3.5 GO:0015811 L-cystine transport(GO:0015811)
0.5 3.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.5 1.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.5 1.8 GO:0010157 response to chlorate(GO:0010157)
0.4 1.3 GO:0007343 egg activation(GO:0007343)
0.4 4.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.4 4.9 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.4 2.3 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.4 1.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 1.5 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.4 2.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.4 1.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4 6.6 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.4 2.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.4 1.8 GO:0070269 pyroptosis(GO:0070269)
0.3 3.7 GO:0008343 adult feeding behavior(GO:0008343)
0.3 11.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 1.0 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.3 1.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 3.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.3 4.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.3 1.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.3 5.4 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.3 2.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.7 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 18.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 2.5 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2 20.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 2.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 1.0 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.2 1.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 1.7 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.2 13.2 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.2 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
0.1 2.5 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 2.8 GO:0005513 detection of calcium ion(GO:0005513)
0.1 11.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 4.5 GO:0045730 respiratory burst(GO:0045730)
0.1 0.5 GO:0019249 lactate biosynthetic process(GO:0019249)
0.1 1.4 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.1 3.9 GO:0009303 rRNA transcription(GO:0009303)
0.1 2.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.3 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.1 5.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 14.6 GO:0007224 smoothened signaling pathway(GO:0007224)
0.1 3.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 2.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 2.7 GO:0048485 sympathetic nervous system development(GO:0048485)
0.1 1.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 2.4 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 1.6 GO:0006825 copper ion transport(GO:0006825)
0.1 33.2 GO:0002250 adaptive immune response(GO:0002250)
0.1 1.0 GO:0046514 ceramide catabolic process(GO:0046514)
0.1 0.2 GO:0045628 T-helper 2 cell differentiation(GO:0045064) regulation of T-helper 2 cell differentiation(GO:0045628) positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1 3.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 2.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.6 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 5.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 1.0 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 3.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 9.7 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 2.2 GO:0008347 glial cell migration(GO:0008347)
0.0 3.8 GO:0070268 cornification(GO:0070268)
0.0 0.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 2.7 GO:0030239 myofibril assembly(GO:0030239)
0.0 7.1 GO:0006909 phagocytosis(GO:0006909)
0.0 0.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 1.8 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.8 GO:0097503 sialylation(GO:0097503)
0.0 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 2.2 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.5 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.3 7.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.2 7.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.0 9.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.9 45.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.7 7.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.7 3.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.7 13.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.7 13.1 GO:0036038 MKS complex(GO:0036038)
0.6 3.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.6 5.5 GO:0035869 ciliary transition zone(GO:0035869)
0.6 1.8 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.6 4.1 GO:0036157 outer dynein arm(GO:0036157)
0.6 9.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.5 4.5 GO:0032010 phagolysosome(GO:0032010)
0.4 4.9 GO:0032039 integrator complex(GO:0032039)
0.4 2.2 GO:1990769 proximal neuron projection(GO:1990769)
0.4 2.5 GO:0031415 NatA complex(GO:0031415)
0.3 13.4 GO:0034451 centriolar satellite(GO:0034451)
0.3 5.2 GO:0005922 connexon complex(GO:0005922)
0.3 1.4 GO:0032044 DSIF complex(GO:0032044)
0.3 2.5 GO:0000813 ESCRT I complex(GO:0000813)
0.2 2.8 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.2 GO:0042825 TAP complex(GO:0042825)
0.2 2.5 GO:0005833 hemoglobin complex(GO:0005833)
0.2 2.1 GO:0030897 HOPS complex(GO:0030897)
0.2 5.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 1.0 GO:1990357 terminal web(GO:1990357)
0.1 2.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 3.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 11.9 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 2.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 5.9 GO:0031526 brush border membrane(GO:0031526)
0.1 0.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 7.2 GO:0005902 microvillus(GO:0005902)
0.1 1.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 7.4 GO:0005901 caveola(GO:0005901)
0.1 6.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 3.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 15.0 GO:0030017 sarcomere(GO:0030017)
0.0 4.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 8.2 GO:0001726 ruffle(GO:0001726)
0.0 2.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.1 GO:0035579 specific granule membrane(GO:0035579)
0.0 37.9 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 5.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.1 GO:0043197 dendritic spine(GO:0043197)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.3 GO:0004522 ribonuclease A activity(GO:0004522)
2.2 15.3 GO:0030492 hemoglobin binding(GO:0030492)
2.1 6.3 GO:0016497 substance K receptor activity(GO:0016497)
1.6 9.8 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
1.1 3.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.0 5.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
1.0 3.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.9 5.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.8 2.5 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.8 4.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.8 9.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.8 2.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.8 45.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.8 9.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.7 5.8 GO:0005000 vasopressin receptor activity(GO:0005000)
0.6 2.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.6 4.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.5 3.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5 1.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.5 3.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.5 2.4 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.4 2.7 GO:0051373 FATZ binding(GO:0051373)
0.4 3.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.4 11.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 15.3 GO:0042605 peptide antigen binding(GO:0042605)
0.4 4.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.4 11.2 GO:0071949 FAD binding(GO:0071949)
0.4 3.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 2.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 7.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 2.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 5.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 11.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 4.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 5.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 7.0 GO:0035198 miRNA binding(GO:0035198)
0.3 2.3 GO:0047499 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499)
0.3 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 2.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 6.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 1.7 GO:0019863 IgE binding(GO:0019863)
0.2 2.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 1.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 20.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 1.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 1.0 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 42.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.4 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 3.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.0 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 1.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 9.7 GO:0003823 antigen binding(GO:0003823)
0.1 3.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 1.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 1.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 2.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 1.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 3.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 8.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 7.4 GO:0005179 hormone activity(GO:0005179)
0.1 1.2 GO:0005123 death receptor binding(GO:0005123)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 2.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 4.2 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.6 GO:0043125 ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) ErbB-3 class receptor binding(GO:0043125)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 5.3 GO:0008201 heparin binding(GO:0008201)
0.0 7.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 2.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 4.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 6.9 GO:0005525 GTP binding(GO:0005525)
0.0 1.0 GO:0043621 protein self-association(GO:0043621)
0.0 1.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.8 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.3 20.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 7.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 5.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 6.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 5.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 20.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.6 13.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.6 12.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.5 11.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 4.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 4.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 2.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 7.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 5.4 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.2 2.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 13.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 7.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 5.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 3.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 5.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 3.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 7.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 11.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 5.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 1.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 3.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis