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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TCF21

Z-value: 0.89

Motif logo

Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
ENSG00000118526.7 TCF21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg38_v1_chr6_+_133889105_1338891200.194.9e-03Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_10723307 10.58 ENST00000279550.11
ENST00000228251.9
Y-box binding protein 3
chr17_+_47209035 7.72 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr19_-_45322867 7.51 ENST00000221476.4
creatine kinase, M-type
chr22_+_22922594 7.30 ENST00000390331.3
immunoglobulin lambda constant 7
chr16_-_31428325 7.16 ENST00000287490.5
cytochrome c oxidase subunit 6A2
chr11_-_5243644 5.90 ENST00000643122.1
hemoglobin subunit delta
chr9_-_33447553 5.65 ENST00000645858.1
ENST00000297991.6
aquaporin 3 (Gill blood group)
chr2_-_218010202 5.40 ENST00000646520.1
tensin 1
chr17_+_47209338 5.29 ENST00000393450.5
myosin light chain 4
chr13_-_41061373 5.24 ENST00000405737.2
E74 like ETS transcription factor 1
chr19_+_11541125 5.05 ENST00000587087.5
calponin 1
chr15_+_63048535 5.04 ENST00000560959.5
tropomyosin 1
chr15_+_63048576 4.97 ENST00000559281.6
tropomyosin 1
chr15_+_63048658 4.90 ENST00000560615.5
ENST00000651577.1
tropomyosin 1
chr5_+_136028979 4.85 ENST00000442011.7
transforming growth factor beta induced
chr7_+_80646436 4.84 ENST00000419819.2
CD36 molecule
chr1_-_30757767 4.48 ENST00000294507.4
lysosomal protein transmembrane 5
chr7_+_142800957 4.41 ENST00000466254.1
T cell receptor beta constant 2
chr8_+_85438850 4.39 ENST00000285381.3
carbonic anhydrase 3
chr16_+_30372291 4.37 ENST00000568749.5
myosin light chain, phosphorylatable, fast skeletal muscle
chr10_+_92689946 4.31 ENST00000282728.10
hematopoietically expressed homeobox
chr1_-_160711803 4.15 ENST00000368045.3
ENST00000368046.8
ENST00000613788.1
CD48 molecule
chr1_+_212565334 4.02 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr15_+_63048436 3.78 ENST00000334895.10
ENST00000404484.9
ENST00000558910.3
ENST00000317516.12
tropomyosin 1
chr19_-_17075038 3.74 ENST00000593360.1
HAUS augmin like complex subunit 8
chr4_+_8182066 3.67 ENST00000508641.2
SH3 domain and tetratricopeptide repeats 1
chr11_+_1922779 3.57 ENST00000641119.1
ENST00000641225.1
ENST00000641787.1
ENST00000397301.5
ENST00000397304.6
ENST00000446240.1
troponin T3, fast skeletal type
chr6_-_73452124 3.56 ENST00000680833.1
cyclic GMP-AMP synthase
chr11_+_47248924 3.56 ENST00000481889.6
ENST00000436778.5
ENST00000531660.5
ENST00000407404.5
nuclear receptor subfamily 1 group H member 3
chr12_-_104958268 3.53 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
solute carrier family 41 member 2
chr16_+_56936654 3.38 ENST00000563911.5
homocysteine inducible ER protein with ubiquitin like domain 1
chr6_-_39229465 3.36 ENST00000359534.4
potassium two pore domain channel subfamily K member 5
chr6_-_159745186 3.30 ENST00000537657.5
superoxide dismutase 2
chr2_+_87338511 3.25 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr14_+_24115299 3.20 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr1_+_22636577 3.17 ENST00000374642.8
ENST00000438241.1
complement C1q A chain
chr9_+_97853217 3.12 ENST00000375123.5
forkhead box E1
chr1_+_171185293 3.04 ENST00000209929.10
flavin containing dimethylaniline monoxygenase 2
chr12_-_10130241 2.96 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr2_-_88979016 2.94 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr10_-_29634964 2.93 ENST00000375398.6
ENST00000355867.8
supervillin
chr18_+_3247778 2.91 ENST00000217652.8
ENST00000578611.5
ENST00000583449.1
myosin light chain 12A
chr14_-_22819721 2.89 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
solute carrier family 7 member 7
chr3_-_127590707 2.88 ENST00000296210.11
ENST00000355552.8
transmembrane protein adipocyte associated 1
chr11_-_59866478 2.82 ENST00000257264.4
transcobalamin 1
chr6_-_41705813 2.74 ENST00000419574.6
ENST00000445214.2
transcription factor EB
chr22_-_50526130 2.71 ENST00000535425.5
ENST00000638598.2
synthesis of cytochrome C oxidase 2
chr9_+_122375286 2.69 ENST00000373698.7
prostaglandin-endoperoxide synthase 1
chr11_+_47248885 2.69 ENST00000395397.7
ENST00000405576.5
nuclear receptor subfamily 1 group H member 3
chr15_+_43792305 2.65 ENST00000249786.9
ENST00000409960.6
ENST00000409646.5
ENST00000339624.9
ENST00000409291.5
ENST00000402131.5
ENST00000403425.5
ENST00000430901.1
small EDRK-rich factor 2
chr18_+_57352541 2.62 ENST00000324000.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr16_+_83899079 2.61 ENST00000262430.6
malonyl-CoA decarboxylase
chr8_-_41665261 2.58 ENST00000522231.5
ENST00000314214.12
ENST00000348036.8
ENST00000522543.5
ankyrin 1
chr2_+_90234809 2.57 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr4_+_37891060 2.55 ENST00000261439.9
ENST00000508802.5
ENST00000402522.1
TBC1 domain family member 1
chr11_-_62573846 2.54 ENST00000329251.5
eukaryotic translation elongation factor 1 gamma
chr9_+_6757940 2.54 ENST00000381309.8
lysine demethylase 4C
chr21_+_10521569 2.54 ENST00000612957.4
ENST00000427445.6
ENST00000612746.1
ENST00000618007.5
transmembrane phosphatase with tensin homology
chr5_-_170389349 2.53 ENST00000274629.9
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr1_-_20786610 2.50 ENST00000375000.5
ENST00000312239.10
ENST00000419490.5
ENST00000414993.1
ENST00000443615.1
heterochromatin protein 1 binding protein 3
chr5_+_50667405 2.48 ENST00000505554.5
poly(ADP-ribose) polymerase family member 8
chr2_+_102104563 2.46 ENST00000409589.5
ENST00000409329.5
interleukin 1 receptor type 1
chr1_-_150765735 2.46 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr21_+_10521536 2.44 ENST00000622113.4
transmembrane phosphatase with tensin homology
chr12_-_10130143 2.38 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr15_+_94297939 2.36 ENST00000357742.9
multiple C2 and transmembrane domain containing 2
chr8_-_41665200 2.34 ENST00000335651.6
ankyrin 1
chr1_+_103745323 2.31 ENST00000684141.1
amylase alpha 1C
chr13_+_50909905 2.27 ENST00000644034.1
ENST00000645955.1
ribonuclease H2 subunit B
chr2_+_230416156 2.25 ENST00000427101.6
SP100 nuclear antigen
chr11_+_59142728 2.24 ENST00000528737.5
FAM111 trypsin like peptidase A
chrX_-_107717054 2.19 ENST00000503515.1
ENST00000372397.6
TSC22 domain family member 3
chr6_-_31728877 2.18 ENST00000437288.5
dimethylarginine dimethylaminohydrolase 2
chr7_+_150716603 2.18 ENST00000307194.6
ENST00000611999.4
GTPase, IMAP family member 1
GIMAP1-GIMAP5 readthrough
chr8_-_70607654 2.15 ENST00000521425.5
translocation associated membrane protein 1
chr5_-_177311882 2.10 ENST00000513169.1
ENST00000423571.6
ENST00000502529.1
ENST00000427908.6
MAX dimerization protein 3
chr1_+_59814939 2.10 ENST00000371208.5
hook microtubule tethering protein 1
chr8_-_66667138 2.10 ENST00000310421.5
valosin containing protein interacting protein 1
chr7_-_99971845 2.09 ENST00000419575.1
alpha-2-glycoprotein 1, zinc-binding
chr12_+_6951345 2.05 ENST00000318974.14
ENST00000541698.5
ENST00000542462.1
protein tyrosine phosphatase non-receptor type 6
chr12_+_6951271 2.04 ENST00000456013.5
protein tyrosine phosphatase non-receptor type 6
chr13_+_50910018 2.04 ENST00000645990.1
ENST00000642995.1
ENST00000636524.2
ENST00000643159.1
ENST00000645618.1
ENST00000611510.5
ENST00000642454.1
ENST00000646709.1
ribonuclease H2 subunit B
chr17_+_42851167 2.02 ENST00000613571.1
ENST00000308423.7
amine oxidase copper containing 3
chrX_-_11427725 2.02 ENST00000380736.5
Rho GTPase activating protein 6
chr20_-_54173516 2.01 ENST00000395955.7
cytochrome P450 family 24 subfamily A member 1
chr6_+_31587185 2.00 ENST00000376092.7
ENST00000376086.7
ENST00000303757.12
ENST00000376093.6
leukocyte specific transcript 1
chr5_+_122312229 2.00 ENST00000261368.13
synuclein alpha interacting protein
chr10_-_28282086 1.99 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr10_-_50885619 1.99 ENST00000373997.8
APOBEC1 complementation factor
chr10_-_50885656 1.96 ENST00000374001.6
ENST00000395489.6
ENST00000282641.6
ENST00000395495.5
ENST00000373995.7
ENST00000414883.1
APOBEC1 complementation factor
chr10_+_96832252 1.95 ENST00000676187.1
ENST00000675687.1
ENST00000676123.1
ENST00000675471.1
ENST00000371103.8
ENST00000421806.4
ENST00000675250.1
ENST00000540664.6
ENST00000676414.1
ligand dependent nuclear receptor corepressor
chr11_+_59142811 1.94 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111 trypsin like peptidase A
chr17_+_39927724 1.94 ENST00000377924.6
ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
leucine rich repeat containing 3C
novel transcript
chr1_-_9069608 1.88 ENST00000377424.9
solute carrier family 2 member 5
chr6_-_31729260 1.83 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr18_+_3448456 1.83 ENST00000549780.5
TGFB induced factor homeobox 1
chr15_-_78811415 1.81 ENST00000388820.5
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr22_-_23580223 1.79 ENST00000249053.3
ENST00000330377.3
ENST00000438703.1
immunoglobulin lambda like polypeptide 1
chr6_-_31729478 1.79 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chr11_+_33039561 1.79 ENST00000334274.9
t-complex 11 like 1
chr2_+_233693659 1.78 ENST00000406651.1
UDP glucuronosyltransferase family 1 member A6
chr7_-_11832190 1.78 ENST00000423059.9
ENST00000617773.1
thrombospondin type 1 domain containing 7A
chr15_+_43792839 1.75 ENST00000409614.1
small EDRK-rich factor 2
chr8_-_20183127 1.73 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr12_+_121888751 1.72 ENST00000261817.6
ENST00000538613.5
ENST00000542602.1
ENST00000541212.6
proteasome 26S subunit, non-ATPase 9
chr11_+_112086853 1.71 ENST00000528182.5
ENST00000528048.5
ENST00000375549.8
ENST00000528021.6
ENST00000526592.5
ENST00000525291.5
succinate dehydrogenase complex subunit D
chr12_-_10849464 1.69 ENST00000544994.5
ENST00000228811.8
ENST00000540107.2
proline rich 4
chr20_-_1184981 1.68 ENST00000429036.2
transmembrane protein 74B
chr7_+_150737382 1.68 ENST00000358647.5
GTPase, IMAP family member 5
chr11_-_30016945 1.68 ENST00000328224.7
potassium voltage-gated channel subfamily A member 4
chr11_-_112086727 1.68 ENST00000504148.3
ENST00000541231.1
translocase of inner mitochondrial membrane 8 homolog B
chrX_+_108091665 1.67 ENST00000345734.7
autophagy related 4A cysteine peptidase
chr4_+_8229170 1.67 ENST00000511002.6
SH3 domain and tetratricopeptide repeats 1
chr8_-_71361860 1.66 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr2_+_6877768 1.66 ENST00000382040.4
radical S-adenosyl methionine domain containing 2
chr13_+_76992412 1.63 ENST00000636705.1
CLN5 intracellular trafficking protein
chr11_+_7576408 1.63 ENST00000533792.5
PPFIA binding protein 2
chr15_+_40695423 1.63 ENST00000526763.6
ENST00000532743.6
RAD51 recombinase
chr6_-_31729785 1.61 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr6_+_31587268 1.60 ENST00000396101.7
ENST00000490742.5
leukocyte specific transcript 1
chr17_+_4833331 1.60 ENST00000355280.11
ENST00000347992.11
misshapen like kinase 1
chr1_-_179575924 1.60 ENST00000367615.9
ENST00000367616.4
NPHS2 stomatin family member, podocin
chr12_+_104064520 1.60 ENST00000229330.9
host cell factor C2
chr22_-_50526337 1.60 ENST00000651490.1
ENST00000543927.6
thymidine phosphorylase
synthesis of cytochrome C oxidase 2
chrX_+_108091752 1.58 ENST00000457035.5
ENST00000372232.8
autophagy related 4A cysteine peptidase
chr22_-_36528897 1.57 ENST00000405442.5
ENST00000402116.2
eukaryotic translation initiation factor 3 subunit D
chr2_-_127643212 1.57 ENST00000409286.5
LIM zinc finger domain containing 2
chr1_-_165445220 1.57 ENST00000619224.1
retinoid X receptor gamma
chr7_-_128775793 1.56 ENST00000249389.3
opsin 1, short wave sensitive
chr13_+_50909745 1.56 ENST00000422660.6
ENST00000645188.1
ENST00000646731.1
ENST00000643774.1
ENST00000646960.1
ENST00000637648.2
ENST00000336617.8
ribonuclease H2 subunit B
chr8_-_20183090 1.55 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr1_-_9069797 1.52 ENST00000473209.1
solute carrier family 2 member 5
chr14_-_106374129 1.52 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr13_-_77919390 1.51 ENST00000475537.2
ENST00000646605.1
endothelin receptor type B
chrX_+_149774068 1.51 ENST00000370416.4
heat shock transcription factor family, X-linked 1
chr10_-_7619660 1.51 ENST00000613909.4
inter-alpha-trypsin inhibitor heavy chain 5
chr6_-_31680377 1.48 ENST00000383237.4
lymphocyte antigen 6 family member G5C
chr4_+_127730386 1.46 ENST00000281154.6
solute carrier family 25 member 31
chr1_+_27935022 1.46 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr11_+_65386611 1.45 ENST00000531296.1
ENST00000533782.5
ENST00000355991.9
ENST00000317568.10
ENST00000416776.6
ENST00000526201.1
FERM domain containing 8
chr3_+_8733779 1.44 ENST00000343849.3
ENST00000397368.2
caveolin 3
chr8_-_98825628 1.44 ENST00000617590.1
ENST00000518165.5
ENST00000419617.7
serine/threonine kinase 3
chr11_-_615570 1.44 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr9_+_116153783 1.41 ENST00000328252.4
pappalysin 1
chr2_+_230416239 1.40 ENST00000409824.5
ENST00000409341.5
ENST00000409112.5
SP100 nuclear antigen
chr8_-_71362054 1.38 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr4_+_145482761 1.37 ENST00000507367.1
ENST00000394092.6
ENST00000515385.1
SMAD family member 1
chr6_-_33192454 1.36 ENST00000395194.1
ENST00000341947.7
ENST00000374708.8
collagen type XI alpha 2 chain
chr1_-_15944348 1.35 ENST00000444358.1
zinc finger and BTB domain containing 17
chr13_-_77919459 1.35 ENST00000643890.1
endothelin receptor type B
chr1_-_9069572 1.34 ENST00000377414.7
solute carrier family 2 member 5
chr17_-_7394800 1.34 ENST00000574401.5
phospholipid scramblase 3
chr9_+_34646654 1.33 ENST00000378842.8
galactose-1-phosphate uridylyltransferase
chr2_+_232697299 1.33 ENST00000476995.5
ENST00000427233.5
ENST00000629305.2
ENST00000428883.5
ENST00000456491.5
ENST00000409480.5
ENST00000492910.5
ENST00000464402.5
ENST00000490612.5
ENST00000475359.6
ENST00000421433.5
ENST00000425040.5
ENST00000430720.5
ENST00000409547.5
ENST00000373563.9
ENST00000423659.5
ENST00000409196.7
ENST00000488734.5
ENST00000409451.7
ENST00000429187.5
ENST00000440945.5
GRB10 interacting GYF protein 2
chr1_+_21977014 1.33 ENST00000337107.11
chymotrypsin like elastase 3B
chr17_-_7290392 1.33 ENST00000571464.1
Y-box binding protein 2
chr12_+_71839707 1.32 ENST00000482439.6
ENST00000550746.5
ENST00000491063.5
ENST00000319106.12
ENST00000485960.7
TBC1 domain family member 15
chr15_+_63504583 1.32 ENST00000380324.8
ENST00000561442.5
ENST00000560070.5
ubiquitin specific peptidase 3
chr3_+_51671175 1.30 ENST00000614067.4
ENST00000457573.5
ENST00000611400.4
ENST00000412249.5
ENST00000425781.5
ENST00000341333.10
ENST00000415259.5
ENST00000395057.5
ENST00000416589.5
testis expressed 264, ER-phagy receptor
chr11_+_33039996 1.28 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
t-complex 11 like 1
chr17_-_44947637 1.28 ENST00000587309.5
ENST00000593135.6
kinesin family member 18B
chr14_-_106811131 1.28 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr4_-_8428424 1.28 ENST00000514423.1
ENST00000503233.5
acyl-CoA oxidase 3, pristanoyl
chr1_-_167553745 1.27 ENST00000370509.5
cellular repressor of E1A stimulated genes 1
chr1_+_186296267 1.26 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
proteoglycan 4
chr9_+_27109200 1.26 ENST00000380036.10
TEK receptor tyrosine kinase
chr2_+_230416190 1.26 ENST00000340126.9
ENST00000432979.5
SP100 nuclear antigen
chr3_-_52826834 1.25 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain 4
chr15_+_63504511 1.24 ENST00000540797.5
ubiquitin specific peptidase 3
chr1_+_99646025 1.24 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr1_+_23743462 1.24 ENST00000609199.1
elongin A
chr3_+_23917693 1.23 ENST00000354811.5
ribosomal protein L15
chr16_+_77191173 1.22 ENST00000248248.8
ENST00000439557.6
ENST00000545553.1
MON1 homolog B, secretory trafficking associated
chr17_-_7178116 1.22 ENST00000380920.8
asialoglycoprotein receptor 1
chr12_+_57434778 1.22 ENST00000309668.3
inhibin subunit beta C
chr11_-_63015831 1.21 ENST00000430500.6
ENST00000336232.7
solute carrier family 22 member 8
chrX_+_15738259 1.20 ENST00000318636.8
carbonic anhydrase 5B
chr11_-_615921 1.20 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
interferon regulatory factor 7
chr1_-_165445088 1.19 ENST00000359842.10
retinoid X receptor gamma
chr16_-_3256587 1.19 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV innate immuity regulator, pyrin
chr9_+_6757633 1.18 ENST00000401787.7
ENST00000381306.7
lysine demethylase 4C
chr6_-_26250625 1.17 ENST00000618052.2
H3 clustered histone 7
chr3_-_54928044 1.17 ENST00000273286.6
leucine rich repeats and transmembrane domains 1
chr22_-_21952827 1.16 ENST00000397495.8
ENST00000263212.10
protein phosphatase, Mg2+/Mn2+ dependent 1F
chr9_+_27109135 1.16 ENST00000519097.5
ENST00000615002.4
TEK receptor tyrosine kinase
chr17_+_7558774 1.16 ENST00000396545.4
TNF superfamily member 13
chr1_+_13749408 1.15 ENST00000343137.8
ENST00000503842.5
ENST00000407521.7
ENST00000505823.5
PR/SET domain 2
chr1_-_150876571 1.14 ENST00000354396.6
ENST00000358595.10
ENST00000505755.5
aryl hydrocarbon receptor nuclear translocator
chr13_-_49936486 1.14 ENST00000378195.6
SPRY domain containing 7
chrX_+_129738942 1.14 ENST00000371106.4
X-prolyl aminopeptidase 2
chr11_-_63015804 1.13 ENST00000535878.5
ENST00000545207.5
solute carrier family 22 member 8
chr4_-_46909206 1.12 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr11_+_14904997 1.12 ENST00000523376.5
calcitonin related polypeptide beta
chr12_+_12891554 1.12 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr9_+_27109393 1.12 ENST00000406359.8
TEK receptor tyrosine kinase
chr10_+_35127023 1.11 ENST00000429130.7
ENST00000469949.6
ENST00000460270.5
cAMP responsive element modulator
chr9_-_121050264 1.11 ENST00000223642.3
complement C5
chr9_+_34646589 1.10 ENST00000450095.6
galactose-1-phosphate uridylyltransferase
chr12_-_64759395 1.10 ENST00000258145.8
ENST00000543646.5
ENST00000542058.5
glucosamine (N-acetyl)-6-sulfatase
chr20_+_31739260 1.09 ENST00000340513.4
ENST00000300403.11
TPX2 microtubule nucleation factor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 18.7 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
2.1 6.2 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.4 4.3 GO:0061011 hepatic duct development(GO:0061011)
1.3 4.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.3 10.6 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
1.1 5.7 GO:0070295 renal water absorption(GO:0070295)
1.1 4.5 GO:0060023 soft palate development(GO:0060023)
1.0 4.9 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.8 2.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.8 2.5 GO:0034769 basement membrane disassembly(GO:0034769)
0.8 4.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.8 3.2 GO:0051697 protein delipidation(GO:0051697)
0.8 2.4 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.8 1.6 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.8 4.7 GO:0097319 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.7 3.3 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.7 4.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.7 3.3 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.6 2.5 GO:1903413 cellular response to bile acid(GO:1903413)
0.6 1.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.5 3.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.5 4.8 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5 2.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.5 1.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.5 2.6 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.5 2.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.5 7.5 GO:0006600 creatine metabolic process(GO:0006600)
0.5 1.4 GO:0035995 detection of muscle stretch(GO:0035995)
0.5 3.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.4 3.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 1.3 GO:0009386 translational attenuation(GO:0009386)
0.4 7.4 GO:0006527 arginine catabolic process(GO:0006527)
0.4 2.9 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.4 1.6 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.4 1.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.4 3.0 GO:0070995 NADPH oxidation(GO:0070995)
0.4 5.0 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4 1.4 GO:0042369 vitamin D catabolic process(GO:0042369)
0.4 7.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 1.0 GO:0060005 vestibular reflex(GO:0060005)
0.3 3.0 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 12.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.3 1.7 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 2.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 1.0 GO:1901656 glucoside transport(GO:0042946) glycoside transport(GO:1901656)
0.3 5.9 GO:0015671 oxygen transport(GO:0015671)
0.3 1.2 GO:0019086 late viral transcription(GO:0019086)
0.3 20.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 1.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 0.9 GO:0060406 positive regulation of penile erection(GO:0060406)
0.3 3.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3 3.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 4.9 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 2.2 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 0.8 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.6 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.3 2.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 0.8 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.3 6.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 1.0 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.2 2.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.2 1.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 0.7 GO:1904383 response to sodium phosphate(GO:1904383)
0.2 2.8 GO:0006824 cobalt ion transport(GO:0006824)
0.2 0.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 4.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.2 0.9 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.2 0.7 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.2 2.9 GO:0040016 embryonic cleavage(GO:0040016)
0.2 0.7 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 5.2 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.2 0.6 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.2 1.9 GO:0006167 AMP biosynthetic process(GO:0006167)
0.2 2.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 3.5 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.2 1.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 1.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 0.9 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 1.6 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.2 1.0 GO:1903232 melanosome assembly(GO:1903232)
0.2 1.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 2.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.6 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.9 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 2.1 GO:0048298 regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 1.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 1.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.4 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 2.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.9 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 1.6 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 2.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.3 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.1 0.9 GO:0070166 enamel mineralization(GO:0070166)
0.1 2.5 GO:0070828 heterochromatin organization(GO:0070828)
0.1 5.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 1.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.6 GO:0035803 egg coat formation(GO:0035803)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.8 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 2.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.0 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.5 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 1.7 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.8 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 3.9 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 2.8 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 1.6 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1 0.7 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 0.7 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 4.8 GO:0010761 fibroblast migration(GO:0010761)
0.1 2.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 2.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 1.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 5.4 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.1 1.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 2.4 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 0.5 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.1 3.0 GO:0010039 response to iron ion(GO:0010039)
0.1 3.8 GO:0001895 retina homeostasis(GO:0001895)
0.1 1.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 1.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.6 GO:0071872 cellular response to epinephrine stimulus(GO:0071872)
0.1 2.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 2.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 2.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.6 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 8.0 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.1 3.9 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 1.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 4.5 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 3.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 1.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 1.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 5.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.8 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 4.9 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 3.3 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.6 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 4.0 GO:0051225 spindle assembly(GO:0051225)
0.0 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 2.9 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 2.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.5 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.9 GO:0033198 response to ATP(GO:0033198) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 4.1 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.7 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 1.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 4.4 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.8 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.5 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 1.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 2.4 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.3 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.3 GO:0002576 platelet degranulation(GO:0002576)
0.0 2.0 GO:0030041 actin filament polymerization(GO:0030041)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.3 18.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.3 6.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
1.0 4.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.8 3.2 GO:0005602 complement component C1 complex(GO:0005602)
0.6 9.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.5 2.1 GO:0070695 FHF complex(GO:0070695)
0.5 3.4 GO:1990037 Lewy body core(GO:1990037)
0.5 4.2 GO:0070652 HAUS complex(GO:0070652)
0.5 1.4 GO:0005592 collagen type XI trimer(GO:0005592)
0.4 4.9 GO:0030870 Mre11 complex(GO:0030870)
0.4 5.9 GO:0005833 hemoglobin complex(GO:0005833)
0.4 4.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 3.3 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.4 2.5 GO:0036021 endolysosome lumen(GO:0036021)
0.3 1.7 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.3 2.9 GO:0036449 microtubule minus-end(GO:0036449)
0.3 14.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 0.8 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 4.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 1.0 GO:0031905 early endosome lumen(GO:0031905)
0.2 1.3 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 2.6 GO:0070938 contractile ring(GO:0070938)
0.2 18.8 GO:0016459 myosin complex(GO:0016459)
0.2 11.4 GO:0005844 polysome(GO:0005844)
0.2 1.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 3.6 GO:0005861 troponin complex(GO:0005861)
0.2 3.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 1.8 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.2 1.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 2.5 GO:0000786 nucleosome(GO:0000786)
0.1 1.1 GO:0005579 membrane attack complex(GO:0005579)
0.1 4.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.3 GO:0005638 lamin filament(GO:0005638)
0.1 2.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.2 GO:0070449 elongin complex(GO:0070449)
0.1 0.9 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.6 GO:0000800 lateral element(GO:0000800)
0.1 2.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.1 GO:0043203 axon hillock(GO:0043203)
0.1 3.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1 3.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.8 GO:0032010 phagolysosome(GO:0032010)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.4 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 4.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.9 GO:0042555 MCM complex(GO:0042555)
0.1 1.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.4 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 6.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 9.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.9 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 6.4 GO:0001650 fibrillar center(GO:0001650)
0.0 2.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 5.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 4.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.0 GO:0042629 mast cell granule(GO:0042629)
0.0 1.7 GO:0030880 DNA-directed RNA polymerase complex(GO:0000428) RNA polymerase complex(GO:0030880)
0.0 2.4 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 2.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.0 GO:0005884 actin filament(GO:0005884)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.6 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 2.4 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 13.0 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.6 6.2 GO:0032810 sterol response element binding(GO:0032810)
1.4 5.7 GO:0015254 glycerol channel activity(GO:0015254)
1.1 7.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.9 7.5 GO:0004111 creatine kinase activity(GO:0004111)
0.8 3.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.8 4.7 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.7 2.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.7 2.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.6 2.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.6 4.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 6.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.6 3.6 GO:0030172 troponin C binding(GO:0030172)
0.5 2.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.5 1.6 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.5 1.6 GO:0098808 mRNA cap binding(GO:0098808)
0.5 2.0 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.5 3.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 2.4 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.5 3.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 1.7 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.4 4.9 GO:0070087 chromo shadow domain binding(GO:0070087)
0.4 0.4 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.4 5.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 2.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 2.8 GO:0004645 phosphorylase activity(GO:0004645)
0.3 3.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 3.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 1.0 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.3 1.0 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.3 9.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 5.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 0.8 GO:0055100 adiponectin binding(GO:0055100)
0.3 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 3.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 5.3 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 4.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 14.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 2.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 2.2 GO:0043426 MRF binding(GO:0043426)
0.2 1.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 2.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 0.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 4.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 23.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 0.7 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 1.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 1.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.2 1.9 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 3.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 2.8 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2 1.4 GO:0071253 connexin binding(GO:0071253)
0.2 1.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 1.6 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 1.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 0.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 1.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 2.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.7 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 1.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 4.1 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.6 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 2.1 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 3.2 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.8 GO:0070697 activin receptor binding(GO:0070697) type II activin receptor binding(GO:0070699)
0.1 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.1 11.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.9 GO:0031685 G-protein coupled adenosine receptor activity(GO:0001609) adenosine receptor binding(GO:0031685)
0.1 0.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 2.1 GO:0005537 mannose binding(GO:0005537)
0.1 2.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.1 GO:0008430 selenium binding(GO:0008430)
0.1 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 5.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 2.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 3.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.6 GO:0032190 acrosin binding(GO:0032190)
0.1 0.5 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.8 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.3 GO:0005521 lamin binding(GO:0005521)
0.0 6.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0050544 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0 2.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 2.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.7 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 7.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 2.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.0 3.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 5.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 4.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 3.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 2.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 5.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 2.3 GO:0019838 growth factor binding(GO:0019838)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 3.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.6 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.9 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 13.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 4.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 9.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.4 PID ALK2 PATHWAY ALK2 signaling events
0.1 7.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.5 PID AURORA A PATHWAY Aurora A signaling
0.1 5.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.8 PID EPO PATHWAY EPO signaling pathway
0.1 2.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.1 PID FOXO PATHWAY FoxO family signaling
0.1 2.5 PID ATR PATHWAY ATR signaling pathway
0.0 3.5 PID SHP2 PATHWAY SHP2 signaling
0.0 3.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 3.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 8.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 4.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 4.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 31.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 5.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 5.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 3.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 2.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 4.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 4.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 2.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 7.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.2 2.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 2.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.6 REACTOME OPSINS Genes involved in Opsins
0.1 3.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 4.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 4.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 10.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 7.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 3.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 3.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 4.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 4.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 4.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 2.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 6.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 2.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 7.2 REACTOME TRANSLATION Genes involved in Translation
0.0 1.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 3.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 3.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins