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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TCF7

Z-value: 3.86

Motif logo

Transcription factors associated with TCF7

Gene Symbol Gene ID Gene Info
ENSG00000081059.20 TCF7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7hg38_v1_chr5_+_134142212_1341422680.101.4e-01Click!

Activity profile of TCF7 motif

Sorted Z-values of TCF7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr22_-_41940208 17.52 ENST00000472374.6
centromere protein M
chr2_-_150487658 12.38 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr5_+_32531786 11.34 ENST00000512913.5
SUB1 regulator of transcription
chr12_+_68686951 11.14 ENST00000378905.6
ENST00000229179.9
nucleoporin 107
chr17_+_36492202 10.22 ENST00000612494.4
ENST00000622013.1
zinc finger HIT-type containing 3
chr1_+_67685342 9.54 ENST00000617962.2
growth arrest and DNA damage inducible alpha
chr10_+_52314272 8.82 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr12_-_49188811 8.81 ENST00000295766.9
tubulin alpha 1a
chr1_-_45542726 7.97 ENST00000676549.1
peroxiredoxin 1
chr13_+_28659100 7.93 ENST00000460403.1
ENST00000380842.5
proteasome maturation protein
chr7_-_95434951 7.85 ENST00000478801.5
ENST00000469926.5
ENST00000493290.5
ENST00000222572.8
ENST00000633531.1
ENST00000490778.5
ENST00000433091.6
paraoxonase 2
chr5_+_155013755 7.71 ENST00000435029.6
kinesin family member 4B
chr8_-_100950549 7.63 ENST00000395951.7
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr16_-_81096163 7.58 ENST00000566566.2
ENST00000569885.6
ENST00000561801.2
ENST00000639689.1
ENST00000638948.1
ENST00000564536.2
ENST00000638192.1
ENST00000640345.1
glycine cleavage system protein H
novel protein
novel protein
chr3_+_159852933 7.46 ENST00000482804.1
schwannomin interacting protein 1
chr1_+_67685170 7.31 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr17_-_67366562 7.16 ENST00000356126.8
ENST00000357146.4
proteasome 26S subunit, non-ATPase 12
chr4_-_7068033 7.14 ENST00000264954.5
GrpE like 1, mitochondrial
chr12_-_54259531 6.91 ENST00000550411.5
ENST00000439541.6
chromobox 5
chr1_-_74732997 6.72 ENST00000370872.7
ENST00000370871.7
ENST00000340866.10
ENST00000370870.5
crystallin zeta
chr1_-_74733253 6.44 ENST00000417775.5
crystallin zeta
chr4_-_138242325 6.11 ENST00000280612.9
solute carrier family 7 member 11
chr6_+_63571702 6.05 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr7_-_95435329 6.04 ENST00000633192.1
paraoxonase 2
chr7_+_56051756 5.64 ENST00000275603.9
chaperonin containing TCP1 subunit 6A
chr17_+_59619885 5.52 ENST00000269122.8
ENST00000580081.1
ENST00000579456.5
clathrin heavy chain
chr7_+_130492066 5.17 ENST00000223215.10
ENST00000437945.6
mesoderm specific transcript
chr11_-_123059413 5.00 ENST00000524552.5
heat shock protein family A (Hsp70) member 8
chr3_+_133784020 4.87 ENST00000466490.7
SRP receptor subunit beta
chr12_+_49265071 4.85 ENST00000549183.1
ENST00000639419.1
ENST00000301072.11
tubulin alpha 1c
chr7_+_95485898 4.81 ENST00000428113.5
ankyrin repeat and SOCS box containing 4
chr7_+_5592805 4.69 ENST00000382361.8
fascin actin-bundling protein 1
chr10_+_28677487 4.49 ENST00000375533.6
BMP and activin membrane bound inhibitor
chr7_-_108003122 4.46 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
laminin subunit beta 1
chr15_+_76931704 4.41 ENST00000320963.9
ENST00000394885.8
ENST00000394883.3
reticulocalbin 2
chr14_+_60734727 4.37 ENST00000261245.9
ENST00000539616.6
MNAT1 component of CDK activating kinase
chr5_-_16936231 4.36 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
myosin X
chr5_+_75337348 4.26 ENST00000681271.1
3-hydroxy-3-methylglutaryl-CoA reductase
chr11_+_19712823 4.23 ENST00000396085.6
ENST00000349880.9
neuron navigator 2
chr19_+_40751179 4.22 ENST00000243563.8
ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr1_-_209651291 4.19 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chrX_+_101390976 4.18 ENST00000392994.7
ribosomal protein L36a
chr12_+_21501780 4.17 ENST00000229314.10
ENST00000542038.5
ENST00000540141.5
ENST00000631252.2
golgi transport 1B
chrX_+_101390824 4.17 ENST00000427805.6
ENST00000614077.4
ribosomal protein L36a
chr1_-_53328053 4.14 ENST00000371454.6
ENST00000667377.1
ENST00000306052.12
ENST00000668448.1
LDL receptor related protein 8
chr12_-_52573816 4.13 ENST00000549343.5
ENST00000305620.3
keratin 74
chr2_+_112645930 4.09 ENST00000272542.8
solute carrier family 20 member 1
chr5_+_75337192 4.09 ENST00000680160.1
3-hydroxy-3-methylglutaryl-CoA reductase
chr18_+_3449817 4.01 ENST00000407501.6
TGFB induced factor homeobox 1
chrX_+_101391000 4.01 ENST00000553110.8
ENST00000409338.5
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr3_-_79767987 4.01 ENST00000464233.6
roundabout guidance receptor 1
chrX_+_101391202 3.82 ENST00000471855.1
ribosomal protein L36a
chr14_-_34875348 3.82 ENST00000360310.6
bromodomain adjacent to zinc finger domain 1A
chr14_-_45134454 3.76 ENST00000396062.4
FKBP prolyl isomerase 3
chr12_+_103965863 3.74 ENST00000392872.8
ENST00000537100.5
thymine DNA glycosylase
chr1_-_33036927 3.69 ENST00000354858.11
adenylate kinase 2
chr2_+_233712905 3.66 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr12_+_120694167 3.58 ENST00000535656.1
malectin
chr6_-_158644709 3.48 ENST00000367089.8
dynein light chain Tctex-type 1
chr8_-_73293616 3.47 ENST00000352983.7
ENST00000396467.5
ribosomal protein L7
chr5_+_36166556 3.46 ENST00000677886.1
S-phase kinase associated protein 2
chr18_+_3450036 3.45 ENST00000546979.5
ENST00000343820.10
ENST00000551402.1
ENST00000577543.5
TGFB induced factor homeobox 1
chr22_+_38681941 3.38 ENST00000216034.6
translocase of outer mitochondrial membrane 22
chr19_+_58387260 3.35 ENST00000598098.5
ENST00000598495.5
ENST00000196551.8
ENST00000596046.1
ribosomal protein S5
chr1_+_182839338 3.35 ENST00000367549.4
DExH-box helicase 9
chr3_-_197298000 3.30 ENST00000664991.1
discs large MAGUK scaffold protein 1
chr1_-_32336224 3.23 ENST00000329421.8
MARCKS like 1
chr8_+_73008850 3.18 ENST00000679115.1
ENST00000517390.2
ENST00000678860.1
ENST00000678518.1
ENST00000276602.10
ENST00000276603.10
ENST00000518874.6
telomeric repeat binding factor 1
chr7_-_56034133 3.13 ENST00000421626.5
phosphoserine phosphatase
chr14_-_34874887 3.12 ENST00000382422.6
bromodomain adjacent to zinc finger domain 1A
chr1_-_33036840 3.11 ENST00000548033.5
ENST00000487289.1
ENST00000626911.1
ENST00000673291.1
ENST00000480134.5
ENST00000373449.7
ENST00000672715.1
ENST00000467905.5
ENST00000629371.2
adenylate kinase 2
chr9_-_120926752 3.10 ENST00000373887.8
TNF receptor associated factor 1
chr1_-_53327883 3.09 ENST00000668071.1
ENST00000465675.6
ENST00000354412.7
ENST00000347547.7
ENST00000659993.1
ENST00000658277.1
ENST00000657895.1
ENST00000662604.1
LDL receptor related protein 8
chr7_+_87876472 3.09 ENST00000265728.6
DBF4 zinc finger
chr3_-_45884685 3.06 ENST00000684620.1
leucine zipper transcription factor like 1
chr17_-_21042901 3.00 ENST00000261497.9
ubiquitin specific peptidase 22
chr2_-_28870266 2.99 ENST00000306108.10
tRNA methyltransferase 61B
chr2_-_27370009 2.92 ENST00000451130.6
eukaryotic translation initiation factor 2B subunit delta
chr22_-_46738205 2.92 ENST00000216264.13
ceramide kinase
chr5_-_141320755 2.91 ENST00000624761.1
ENST00000313368.8
TATA-box binding protein associated factor 7
chr22_-_17773976 2.84 ENST00000317361.11
BH3 interacting domain death agonist
chr7_+_134891566 2.79 ENST00000424922.5
ENST00000495522.1
caldesmon 1
chr1_+_39215255 2.79 ENST00000671089.1
microtubule actin crosslinking factor 1
chrX_+_101408198 2.79 ENST00000316594.6
heterogeneous nuclear ribonucleoprotein H2
chr1_+_1033987 2.74 ENST00000651234.1
ENST00000652369.1
agrin
chr16_-_73048104 2.71 ENST00000268489.10
zinc finger homeobox 3
chr22_+_19962537 2.63 ENST00000449653.5
catechol-O-methyltransferase
chrX_+_12975216 2.61 ENST00000380635.5
thymosin beta 4 X-linked
chr4_-_68349981 2.58 ENST00000510746.1
ENST00000355665.7
ENST00000344157.9
YTH domain containing 1
chr4_+_70993542 2.58 ENST00000504730.5
ENST00000504952.1
ENST00000286648.10
deoxycytidine kinase
chr12_-_55727080 2.56 ENST00000548898.5
ENST00000552067.5
CD63 molecule
chr4_-_68349750 2.56 ENST00000579690.5
YTH domain containing 1
chr19_-_2328573 2.55 ENST00000587502.2
ENST00000252622.15
ENST00000585409.2
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr11_-_2992373 2.54 ENST00000620138.4
ENST00000526115.5
nucleosome assembly protein 1 like 4
chr7_-_148884266 2.49 ENST00000483967.5
ENST00000320356.7
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr8_-_89984231 2.46 ENST00000517337.1
ENST00000409330.5
nibrin
chr22_-_17774412 2.44 ENST00000342111.9
ENST00000622694.5
BH3 interacting domain death agonist
chr10_+_5048748 2.40 ENST00000602997.5
ENST00000439082.7
aldo-keto reductase family 1 member C3
chr11_-_10808304 2.36 ENST00000532082.6
eukaryotic translation initiation factor 4 gamma 2
chr3_-_197298558 2.34 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
discs large MAGUK scaffold protein 1
chr1_-_94927079 2.30 ENST00000370206.9
ENST00000394202.8
calponin 3
chr6_+_63572472 2.29 ENST00000370651.7
ENST00000626021.3
novel protein
protein tyrosine phosphatase 4A1
chr7_+_134891400 2.26 ENST00000393118.6
caldesmon 1
chr17_+_42998264 2.23 ENST00000589037.5
ribosomal protein L27
chr6_-_106974721 2.22 ENST00000606017.2
ENST00000620405.1
CD24 molecule
chr4_-_52038260 2.22 ENST00000381431.10
sarcoglycan beta
chr11_-_28108109 2.21 ENST00000263181.7
kinesin family member 18A
chr8_-_89984609 2.21 ENST00000519426.5
ENST00000265433.8
nibrin
chr4_+_1871373 2.21 ENST00000508803.6
ENST00000507820.5
ENST00000514045.5
nuclear receptor binding SET domain protein 2
chrX_+_54809060 2.15 ENST00000396224.1
MAGE family member D2
chr19_-_45602153 2.15 ENST00000544371.1
ENST00000323040.5
outer mitochondrial membrane lipid metabolism regulator OPA3
G protein-coupled receptor 4
chr12_+_49323236 2.13 ENST00000549275.5
ENST00000551245.5
ENST00000380327.9
ENST00000548311.5
ENST00000257909.8
ENST00000550346.5
ENST00000550709.5
ENST00000549534.1
ENST00000547807.5
ENST00000551567.1
trophinin associated protein
chr15_-_68206039 2.05 ENST00000395463.3
calmodulin like 4
chr13_+_29428709 2.02 ENST00000542829.1
microtubule associated scaffold protein 2
chr3_+_155870623 1.99 ENST00000295920.7
ENST00000496455.7
guanine monophosphate synthase
chrX_-_103502853 1.96 ENST00000372633.1
RAB40A, member RAS oncogene family
chr1_+_235328959 1.93 ENST00000643758.1
ENST00000497327.1
tubulin folding cofactor E
geranylgeranyl diphosphate synthase 1
chr5_+_86617919 1.92 ENST00000247655.4
ENST00000509578.1
cytochrome c oxidase subunit 7C
chr17_+_42998379 1.89 ENST00000253788.12
ENST00000589913.6
ribosomal protein L27
chr7_-_148884159 1.86 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
enhancer of zeste 2 polycomb repressive complex 2 subunit
chrX_+_52184874 1.84 ENST00000599522.7
ENST00000471932.6
MAGE family member D4
chr19_+_13023958 1.84 ENST00000587760.5
ENST00000585575.5
nuclear factor I X
chr11_-_10808913 1.82 ENST00000527419.6
ENST00000530211.6
ENST00000339995.11
ENST00000530702.2
ENST00000524932.6
ENST00000532570.6
eukaryotic translation initiation factor 4 gamma 2
chr4_+_108620567 1.81 ENST00000502534.5
ENST00000394667.8
ribosomal protein L34
chr5_-_149551381 1.81 ENST00000670598.1
ENST00000657001.1
ENST00000515768.6
ENST00000261798.10
ENST00000377843.8
casein kinase 1 alpha 1
chr3_+_12557050 1.81 ENST00000411987.5
ENST00000170447.12
ENST00000448482.1
ENST00000677142.1
makorin ring finger protein 2
chr7_-_151814636 1.78 ENST00000652047.1
ENST00000650858.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr19_+_1026566 1.74 ENST00000562015.5
ENST00000263097.9
ENST00000348419.7
ENST00000565096.6
ENST00000562958.6
ENST00000568865.3
ENST00000606983.5
ENST00000562075.6
ENST00000607102.1
calponin 2
chr2_-_171894227 1.73 ENST00000422440.7
solute carrier family 25 member 12
chr17_+_77287891 1.73 ENST00000449803.6
ENST00000431235.6
septin 9
chr2_-_197435002 1.73 ENST00000335508.11
ENST00000414963.2
ENST00000487698.5
splicing factor 3b subunit 1
chr2_+_180980566 1.70 ENST00000410062.9
ubiquitin conjugating enzyme E2 E3
chr22_-_38317423 1.66 ENST00000396832.6
ENST00000403904.5
ENST00000405675.7
casein kinase 1 epsilon
chr6_+_125219804 1.66 ENST00000524679.1
TPD52 like 1
chr12_+_53097656 1.65 ENST00000301464.4
insulin like growth factor binding protein 6
chr2_-_216013517 1.65 ENST00000263268.11
melanoregulin
chr12_-_48957365 1.65 ENST00000398092.4
ENST00000539611.1
novel protein
ADP ribosylation factor 3
chr8_+_53880894 1.64 ENST00000276500.4
regulator of G protein signaling 20
chr17_+_28662183 1.63 ENST00000347486.8
ENST00000314616.11
SPT6 homolog, histone chaperone and transcription elongation factor
chrX_+_52184904 1.60 ENST00000375626.7
ENST00000467526.1
MAGE family member D4
chrX_+_103628692 1.60 ENST00000372626.7
transcription elongation factor A like 1
chr8_+_145052447 1.58 ENST00000331434.7
ENST00000648531.1
ENST00000647640.1
ENST00000647724.1
ENST00000648784.1
chromosome 8 open reading frame 33
chr19_+_13024573 1.57 ENST00000358552.7
ENST00000360105.8
ENST00000588228.5
ENST00000676441.1
ENST00000591028.1
nuclear factor I X
chr19_-_13116719 1.56 ENST00000588229.1
ENST00000357720.9
tRNA methyltransferase 1
chr19_+_21397107 1.54 ENST00000596302.5
ENST00000594390.5
ENST00000355504.4
ENST00000392288.7
zinc finger protein 493
chr4_-_7872255 1.53 ENST00000382543.4
actin filament associated protein 1
chr22_+_38656627 1.53 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist
chr11_-_2992267 1.52 ENST00000448187.5
ENST00000532325.6
ENST00000399614.6
ENST00000380542.9
nucleosome assembly protein 1 like 4
chr4_+_108620584 1.52 ENST00000394665.5
ribosomal protein L34
chr2_+_171522227 1.51 ENST00000409484.5
cytochrome b reductase 1
chr4_-_102345196 1.51 ENST00000683412.1
ENST00000682227.1
solute carrier family 39 member 8
chr7_+_120988683 1.50 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr16_-_46689145 1.48 ENST00000299138.12
VPS35 retromer complex component
chr2_-_128028114 1.48 ENST00000259234.10
Sin3A associated protein 130
chr3_+_130894050 1.47 ENST00000510168.6
ATPase secretory pathway Ca2+ transporting 1
chr4_-_128288791 1.45 ENST00000613358.4
ENST00000520121.6
progesterone receptor membrane component 2
chr7_-_151814668 1.44 ENST00000651764.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr3_-_197297523 1.40 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
discs large MAGUK scaffold protein 1
chr2_-_128028010 1.39 ENST00000643581.2
ENST00000450957.1
Sin3A associated protein 130
chr3_+_119173564 1.38 ENST00000264234.8
ENST00000479520.5
ENST00000494855.5
uroplakin 1B
chr4_+_108620616 1.36 ENST00000506397.5
ENST00000394668.2
ribosomal protein L34
chr1_-_147670513 1.35 ENST00000583509.7
acid phosphatase 6, lysophosphatidic
chr12_+_103965835 1.34 ENST00000266775.13
ENST00000544861.5
thymine DNA glycosylase
chr1_+_15152558 1.34 ENST00000376014.7
ENST00000451326.6
transmembrane protein 51
chr5_-_83673544 1.31 ENST00000503117.1
ENST00000510978.5
hyaluronan and proteoglycan link protein 1
chr21_-_26845402 1.27 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr4_-_145098541 1.26 ENST00000613466.4
ENST00000514390.5
anaphase promoting complex subunit 10
chr12_+_103965798 1.24 ENST00000436021.6
thymine DNA glycosylase
chr3_+_197950176 1.23 ENST00000448864.6
ENST00000647248.2
ribosomal protein L35a
chr13_+_45120493 1.20 ENST00000340473.8
general transcription factor IIF subunit 2
chr3_+_133573637 1.18 ENST00000264993.8
CDV3 homolog
chr8_+_53880867 1.15 ENST00000522225.5
regulator of G protein signaling 20
chr10_-_48652493 1.12 ENST00000435790.6
Rho GTPase activating protein 22
chr17_+_70104848 1.12 ENST00000392670.5
potassium inwardly rectifying channel subfamily J member 16
chr17_-_17582417 1.11 ENST00000395783.5
phosphatidylethanolamine N-methyltransferase
chr22_-_17774482 1.07 ENST00000399765.5
ENST00000614949.4
ENST00000399767.6
BH3 interacting domain death agonist
chr7_+_128862841 1.04 ENST00000249289.5
ENST00000492758.1
ATPase H+ transporting V1 subunit F
chr19_+_44777860 1.03 ENST00000341505.4
ENST00000647358.2
Cbl proto-oncogene C
chr1_-_110390989 1.03 ENST00000369779.9
ENST00000472422.6
solute carrier family 16 member 4
chr15_+_67067780 1.03 ENST00000679624.1
SMAD family member 3
chr7_+_150991005 1.02 ENST00000297494.8
nitric oxide synthase 3
chrX_+_12975083 0.95 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr6_+_26383176 0.95 ENST00000416795.6
ENST00000494184.1
butyrophilin subfamily 2 member A2
chr5_+_43603163 0.93 ENST00000660752.1
ENST00000654405.1
ENST00000344920.9
ENST00000657172.1
ENST00000512996.6
ENST00000671668.1
nicotinamide nucleotide transhydrogenase
chr3_+_119173515 0.91 ENST00000497685.5
uroplakin 1B
chr1_+_11012622 0.89 ENST00000629725.2
ENST00000476201.5
ENST00000240185.8
ENST00000621715.4
TAR DNA binding protein
chr4_-_158159657 0.88 ENST00000590648.5
golgi associated kinase 1B
chr10_-_89414458 0.88 ENST00000371837.5
lipase A, lysosomal acid type
chr4_+_86594301 0.88 ENST00000427191.6
ENST00000411767.7
ENST00000436978.5
ENST00000502971.5
protein tyrosine phosphatase non-receptor type 13
chr5_+_43602648 0.87 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr7_-_78771108 0.87 ENST00000626691.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_-_110391041 0.86 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr3_+_44584953 0.86 ENST00000441021.5
ENST00000322734.2
zinc finger protein 660
chr17_+_77451244 0.85 ENST00000591088.5
septin 9
chr1_-_109393197 0.84 ENST00000538502.5
ENST00000482236.5
sortilin 1
chr6_+_112236806 0.84 ENST00000588837.5
ENST00000590293.5
ENST00000585450.5
ENST00000629766.2
ENST00000590804.5
ENST00000590584.4
ENST00000628122.2
ENST00000627025.1
ENST00000590673.5
ENST00000585611.5
ENST00000587816.2
LAMA4 antisense RNA 1
novel ret finger protein-like 4B
chr9_-_21207143 0.81 ENST00000357374.2
interferon alpha 10
chr11_-_62679055 0.80 ENST00000294119.6
ENST00000529640.5
ENST00000301935.10
ENST00000534176.1
ENST00000616865.4
UBX domain protein 1
chr11_+_65572349 0.79 ENST00000316409.2
ENST00000449319.2
ENST00000530349.2
family with sequence similarity 89 member B
chr8_-_42501224 0.78 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0009996 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996)
2.3 6.8 GO:0006172 ADP biosynthetic process(GO:0006172)
1.9 11.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.6 6.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
1.5 7.6 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.5 4.4 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
1.4 5.5 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
1.0 7.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
1.0 3.1 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
1.0 4.0 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
1.0 5.0 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.0 3.0 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.9 4.7 GO:0030035 microspike assembly(GO:0030035)
0.9 4.7 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.8 4.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) glossopharyngeal nerve development(GO:0021563)
0.8 8.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.8 13.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.8 0.8 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.8 2.4 GO:0016107 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.8 3.2 GO:0031627 telomeric loop formation(GO:0031627) establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.7 16.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.7 10.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.6 7.6 GO:0090168 Golgi reassembly(GO:0090168)
0.6 3.5 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.6 1.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.6 3.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.6 3.3 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.6 2.2 GO:0032913 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.6 2.2 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
0.5 2.7 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.5 2.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.5 7.6 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.5 1.5 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.5 7.9 GO:0043248 proteasome assembly(GO:0043248)
0.5 1.5 GO:1903181 positive regulation of Wnt protein secretion(GO:0061357) regulation of late endosome to lysosome transport(GO:1902822) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of vacuolar transport(GO:1903336)
0.5 6.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.5 17.5 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4 13.9 GO:0019372 lipoxygenase pathway(GO:0019372)
0.4 3.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) negative regulation of interleukin-8 secretion(GO:2000483)
0.4 2.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.4 4.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.4 2.6 GO:0016036 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.4 3.9 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.4 2.1 GO:0072144 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.4 1.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.4 5.6 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.4 4.4 GO:0007512 adult heart development(GO:0007512)
0.4 2.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.4 12.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.4 1.8 GO:0006740 NADPH regeneration(GO:0006740)
0.3 3.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 1.0 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.3 3.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 5.5 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.3 2.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 4.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.3 2.9 GO:0015846 polyamine transport(GO:0015846)
0.3 6.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 8.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.3 0.8 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.3 3.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 1.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 3.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 2.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.2 0.7 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.2 4.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 0.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 0.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 2.6 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2 0.7 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 26.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 4.2 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.2 1.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.8 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 8.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 3.2 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.7 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 1.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 2.6 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.1 1.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 2.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.5 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 5.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.6 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.5 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971) fasciculation of sensory neuron axon(GO:0097155)
0.1 7.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 2.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 1.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 1.4 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.5 GO:0090270 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.1 0.6 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 1.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 3.0 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 17.9 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.8 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.5 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 1.6 GO:0030488 tRNA methylation(GO:0030488)
0.1 3.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.4 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 1.3 GO:0060347 heart trabecula formation(GO:0060347)
0.1 3.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.6 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 2.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 4.1 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 1.6 GO:0032402 melanosome transport(GO:0032402)
0.1 7.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.8 GO:0006600 creatine metabolic process(GO:0006600)
0.0 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 6.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 4.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 4.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 2.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 1.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 2.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 2.9 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.9 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 1.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0072603 interleukin-5 secretion(GO:0072603) regulation of interleukin-5 secretion(GO:2000662)
0.0 0.3 GO:0070914 UV protection(GO:0009650) UV-damage excision repair(GO:0070914)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.1 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 1.9 GO:0007498 mesoderm development(GO:0007498)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 1.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0008623 CHRAC(GO:0008623)
1.9 7.6 GO:0005960 glycine cleavage complex(GO:0005960)
1.8 7.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.6 4.7 GO:0044393 microspike(GO:0044393)
1.5 4.5 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
1.0 3.0 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.8 4.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.7 7.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.7 4.2 GO:0005610 laminin-5 complex(GO:0005610)
0.7 11.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.6 5.0 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.6 5.5 GO:0071439 clathrin complex(GO:0071439)
0.5 6.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.5 3.2 GO:0070187 telosome(GO:0070187)
0.5 4.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.5 1.5 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.5 3.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.5 4.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.4 4.7 GO:0030870 Mre11 complex(GO:0030870)
0.4 4.2 GO:0005614 interstitial matrix(GO:0005614)
0.4 1.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.4 7.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.4 2.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 1.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.3 5.1 GO:0030478 actin cap(GO:0030478)
0.3 5.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 4.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.3 29.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 2.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 4.4 GO:0045120 pronucleus(GO:0045120)
0.3 2.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 4.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 3.0 GO:0000124 SAGA complex(GO:0000124)
0.2 2.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 19.3 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.2 4.4 GO:0032433 filopodium tip(GO:0032433)
0.2 2.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 11.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 3.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 7.7 GO:0005871 kinesin complex(GO:0005871)
0.2 4.0 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.7 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 2.9 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 2.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 4.1 GO:0045095 keratin filament(GO:0045095)
0.1 1.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 5.9 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 15.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.6 GO:0045179 apical cortex(GO:0045179)
0.1 6.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 7.5 GO:0005875 microtubule associated complex(GO:0005875)
0.1 3.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.3 GO:0005605 basal lamina(GO:0005605)
0.1 5.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 6.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 28.2 GO:0016607 nuclear speck(GO:0016607)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 3.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 4.3 GO:0016605 PML body(GO:0016605)
0.0 2.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.8 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 3.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 6.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 3.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 11.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 7.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 13.9 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
3.3 13.2 GO:0070404 NADH binding(GO:0070404)
2.5 7.6 GO:0004047 aminomethyltransferase activity(GO:0004047)
2.1 6.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
2.1 8.4 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
1.4 7.2 GO:0038025 reelin receptor activity(GO:0038025)
1.4 5.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.2 6.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.0 3.0 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.0 8.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.0 4.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.8 3.3 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.8 4.1 GO:1990254 keratin filament binding(GO:1990254)
0.8 9.0 GO:0039706 co-receptor binding(GO:0039706)
0.8 4.9 GO:0005047 signal recognition particle binding(GO:0005047)
0.8 4.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.8 2.4 GO:0045550 geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.8 3.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.7 4.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.7 2.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.5 7.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.5 4.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.5 3.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.5 5.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.5 7.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.4 5.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.4 7.6 GO:0097016 L27 domain binding(GO:0097016)
0.4 3.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 4.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.4 1.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.4 11.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.4 2.6 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.4 9.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 1.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 2.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3 2.8 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.3 1.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 4.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 1.5 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3 2.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.3 2.9 GO:0001727 lipid kinase activity(GO:0001727)
0.3 8.5 GO:0070410 co-SMAD binding(GO:0070410)
0.3 3.4 GO:0015266 protein channel activity(GO:0015266)
0.3 2.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 3.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 10.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.3 1.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 11.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 5.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 0.9 GO:0004771 sterol esterase activity(GO:0004771)
0.2 3.1 GO:0031996 thioesterase binding(GO:0031996)
0.2 4.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 0.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 6.4 GO:0005123 death receptor binding(GO:0005123)
0.2 3.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 3.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 33.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.2 GO:0070697 activin receptor binding(GO:0070697) type II activin receptor binding(GO:0070699)
0.1 6.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.8 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 2.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 2.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 21.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 7.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 6.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 3.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0004111 creatine kinase activity(GO:0004111)
0.1 2.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 3.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.8 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 4.1 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.5 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 4.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 2.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 6.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 2.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 9.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 2.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 16.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 6.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.7 GO:0003774 motor activity(GO:0003774)
0.0 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.7 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 16.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 6.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 8.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 2.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 10.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 7.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 8.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 6.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 3.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 3.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 7.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 7.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 5.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 4.7 PID ATM PATHWAY ATM pathway
0.1 4.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 5.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 5.6 PID AURORA B PATHWAY Aurora B signaling
0.1 3.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.8 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 3.5 PID MYC PATHWAY C-MYC pathway
0.1 9.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 19.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.4 3.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.4 9.9 REACTOME KINESINS Genes involved in Kinesins
0.3 6.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 11.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.3 7.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.3 6.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 7.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.3 5.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 9.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 7.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 7.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 33.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 17.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 12.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 3.7 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.2 3.6 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2 4.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 4.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 8.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 3.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 3.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 2.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 3.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 12.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 4.9 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 2.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 3.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 5.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 5.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.1 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 3.9 REACTOME TRANSLATION Genes involved in Translation
0.1 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 13.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 4.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 3.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 6.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 4.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 2.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 5.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 5.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 2.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER