Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for TCF7L1

Z-value: 1.14

Motif logo

Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
ENSG00000152284.5 TCF7L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L1hg38_v1_chr2_+_85133376_851334740.027.5e-01Click!

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr6_-_106975452 14.70 ENST00000619869.1
ENST00000619133.4
CD24 molecule
chr6_-_106975309 14.70 ENST00000615659.1
CD24 molecule
chr1_-_153550083 12.28 ENST00000368714.1
S100 calcium binding protein A4
chr14_+_75280078 11.07 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr6_-_106974721 10.86 ENST00000606017.2
ENST00000620405.1
CD24 molecule
chr18_+_3450036 10.66 ENST00000546979.5
ENST00000343820.10
ENST00000551402.1
ENST00000577543.5
TGFB induced factor homeobox 1
chr18_+_3449817 10.56 ENST00000407501.6
TGFB induced factor homeobox 1
chr14_-_22982258 9.57 ENST00000555074.1
ENST00000361265.8
novel protein
ajuba LIM protein
chr21_-_44910630 9.32 ENST00000320216.10
ENST00000397852.5
integrin subunit beta 2
chr7_+_80602150 8.77 ENST00000309881.11
CD36 molecule
chr7_-_149028452 8.72 ENST00000413966.1
ENST00000652332.1
protein disulfide isomerase family A member 4
chr7_+_80602200 8.65 ENST00000534394.5
CD36 molecule
chr14_-_64942783 8.45 ENST00000612794.1
glutathione peroxidase 2
chr7_-_149028651 8.37 ENST00000286091.9
protein disulfide isomerase family A member 4
chr7_+_116210501 7.62 ENST00000455989.1
ENST00000358204.9
testin LIM domain protein
chr5_-_176537361 7.62 ENST00000274811.9
ring finger protein 44
chr17_-_7394240 7.34 ENST00000576362.5
ENST00000571078.5
phospholipid scramblase 3
chr14_-_34875348 7.22 ENST00000360310.6
bromodomain adjacent to zinc finger domain 1A
chr17_-_7394514 7.19 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
phospholipid scramblase 3
chr7_-_140176970 7.15 ENST00000397560.7
lysine demethylase 7A
chr14_-_34874887 6.79 ENST00000382422.6
bromodomain adjacent to zinc finger domain 1A
chr17_-_7394800 6.63 ENST00000574401.5
phospholipid scramblase 3
chrX_-_136880715 6.42 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr6_-_169724467 6.35 ENST00000339209.9
PHD finger protein 10
chr7_-_27180230 6.31 ENST00000396344.4
homeobox A10
chr7_+_80646305 6.06 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr20_+_57391388 5.94 ENST00000356208.10
ENST00000440234.6
RNA binding motif protein 38
chr12_+_103965863 5.94 ENST00000392872.8
ENST00000537100.5
thymine DNA glycosylase
chr7_+_80646436 5.82 ENST00000419819.2
CD36 molecule
chrX_+_101390824 5.40 ENST00000427805.6
ENST00000614077.4
ribosomal protein L36a
chr21_+_29299368 5.21 ENST00000399921.5
BTB domain and CNC homolog 1
chr1_+_182839338 5.18 ENST00000367549.4
DExH-box helicase 9
chr12_+_103965835 5.06 ENST00000266775.13
ENST00000544861.5
thymine DNA glycosylase
chr11_+_69641146 4.96 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr12_+_103965798 4.94 ENST00000436021.6
thymine DNA glycosylase
chr6_-_106975616 4.86 ENST00000610952.1
CD24 molecule
chr1_+_109548567 4.74 ENST00000369851.7
G protein subunit alpha i3
chr6_+_143608170 4.72 ENST00000427704.6
ENST00000305766.10
phosphatase and actin regulator 2
chr8_-_101206064 4.66 ENST00000518336.5
ENST00000520454.1
zinc finger protein 706
chr7_-_25228485 4.62 ENST00000222674.2
neuropeptide VF precursor
chr8_-_17246846 4.53 ENST00000628418.1
ENST00000361272.9
ENST00000523917.5
CCR4-NOT transcription complex subunit 7
chrX_-_154371210 4.43 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chrX_+_101391202 4.42 ENST00000471855.1
ribosomal protein L36a
chr11_+_65572349 4.34 ENST00000316409.2
ENST00000449319.2
ENST00000530349.2
family with sequence similarity 89 member B
chr9_-_72364504 4.31 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
zinc finger AN1-type containing 5
chr13_+_29428709 4.28 ENST00000542829.1
microtubule associated scaffold protein 2
chrX_+_101390976 4.27 ENST00000392994.7
ribosomal protein L36a
chr17_-_10518536 4.22 ENST00000226207.6
myosin heavy chain 1
chr12_+_53097656 4.21 ENST00000301464.4
insulin like growth factor binding protein 6
chr15_+_40844018 4.19 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr8_+_30095649 4.13 ENST00000518192.5
leptin receptor overlapping transcript like 1
chr6_+_63571702 4.06 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr19_+_40751179 4.02 ENST00000243563.8
ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr2_+_10043524 4.00 ENST00000305883.6
Kruppel like factor 11
chr3_+_179562886 3.98 ENST00000450518.6
ENST00000392662.5
ENST00000429709.7
ENST00000490364.1
actin like 6A
chrX_+_101391000 3.96 ENST00000553110.8
ENST00000409338.5
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr7_-_148884266 3.91 ENST00000483967.5
ENST00000320356.7
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr17_-_10469558 3.90 ENST00000255381.2
myosin heavy chain 4
chr15_-_101252040 3.82 ENST00000254190.4
chondroitin sulfate synthase 1
chr5_+_134114673 3.79 ENST00000342854.10
ENST00000395029.5
transcription factor 7
chr4_-_121072519 3.68 ENST00000379692.9
neuron derived neurotrophic factor
chr10_+_22316375 3.64 ENST00000376836.8
ENST00000456711.5
ENST00000444869.5
ENST00000475460.6
ENST00000602390.5
ENST00000489125.2
COMM domain containing 3
COMMD3-BMI1 readthrough
chr1_+_32013848 3.63 ENST00000327300.12
ENST00000492989.1
KH RNA binding domain containing, signal transduction associated 1
chr7_+_73830988 3.60 ENST00000340958.4
claudin 4
chr3_-_47781837 3.59 ENST00000254480.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
chr10_+_21524627 3.53 ENST00000651097.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chrX_+_153494970 3.48 ENST00000331595.9
ENST00000431891.1
biglycan
chr7_-_148884159 3.47 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr11_-_5234475 3.46 ENST00000292901.7
ENST00000650601.1
ENST00000417377.1
hemoglobin subunit delta
chr1_-_65067707 3.46 ENST00000672099.1
ENST00000671954.1
ENST00000672434.1
ENST00000673502.1
ENST00000672751.1
Janus kinase 1
chr10_+_22316445 3.42 ENST00000448361.5
COMM domain containing 3
chr7_-_27174274 3.40 ENST00000283921.5
homeobox A10
chr7_-_106285898 3.32 ENST00000424768.2
ENST00000681255.1
nicotinamide phosphoribosyltransferase
chr6_+_118894144 3.31 ENST00000229595.6
anti-silencing function 1A histone chaperone
chr7_+_116672187 3.30 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr18_+_70288991 3.27 ENST00000397942.4
suppressor of cytokine signaling 6
chr11_+_36296281 3.27 ENST00000530639.6
proline rich 5 like
chr17_-_40937445 3.26 ENST00000436344.7
ENST00000485751.1
keratin 23
chr15_+_74782069 3.26 ENST00000220003.14
ENST00000439220.6
C-terminal Src kinase
chr3_+_137764296 3.20 ENST00000306087.3
SRY-box transcription factor 14
chr3_-_160565560 3.20 ENST00000334256.9
ENST00000676866.1
ENST00000469804.1
karyopherin subunit alpha 4
chr14_+_20455185 3.20 ENST00000555414.5
ENST00000553681.5
apurinic/apyrimidinic endodeoxyribonuclease 1
chr8_-_42377227 3.18 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr1_+_93448155 3.15 ENST00000370253.6
formin binding protein 1 like
chr4_+_2818155 3.13 ENST00000511747.6
SH3 domain binding protein 2
chr12_+_54033026 3.06 ENST00000312492.3
homeobox C5
chr17_-_40937641 2.97 ENST00000209718.8
keratin 23
chr7_-_27174253 2.93 ENST00000613671.1
homeobox A10
chr16_-_46831134 2.91 ENST00000394806.6
ENST00000285697.9
chromosome 16 open reading frame 87
chr5_+_72816643 2.90 ENST00000337273.10
ENST00000523768.5
transportin 1
chr8_-_143973520 2.89 ENST00000356346.7
plectin
chr6_-_27473058 2.87 ENST00000683788.1
ENST00000211936.10
zinc finger protein 184
chr17_+_9162935 2.83 ENST00000436734.1
netrin 1
chr10_+_69802424 2.82 ENST00000673802.2
ENST00000517713.5
ENST00000520133.5
ENST00000522165.5
ENST00000673641.2
ENST00000673628.2
collagen type XIII alpha 1 chain
chr14_+_57390544 2.81 ENST00000555166.5
ENST00000556492.6
ENST00000554703.1
N-alpha-acetyltransferase 30, NatC catalytic subunit
chr10_+_21524670 2.78 ENST00000631589.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr2_+_69013379 2.70 ENST00000409349.7
ANTXR cell adhesion molecule 1
chr6_-_27472681 2.67 ENST00000377419.1
zinc finger protein 184
chr14_-_50561119 2.66 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr10_+_69801892 2.59 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
collagen type XIII alpha 1 chain
chr9_+_125748175 2.48 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr6_+_133953210 2.44 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr6_+_108559742 2.44 ENST00000343882.10
forkhead box O3
chrX_+_70268305 2.44 ENST00000374495.7
arrestin 3
chr2_+_227813834 2.39 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr17_+_77451244 2.38 ENST00000591088.5
septin 9
chr20_-_63956382 2.35 ENST00000358711.7
ENST00000354216.11
uridine-cytidine kinase 1 like 1
chr1_+_35883189 2.35 ENST00000674304.1
ENST00000373204.6
ENST00000674426.1
argonaute RISC component 1
chr10_-_97185758 2.35 ENST00000371070.8
slit guidance ligand 1
chr1_+_81800368 2.34 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr4_-_102345196 2.32 ENST00000683412.1
ENST00000682227.1
solute carrier family 39 member 8
chr17_+_81712236 2.31 ENST00000545862.5
ENST00000350690.10
ENST00000331531.9
solute carrier family 25 member 10
chr2_-_169362527 2.29 ENST00000649046.1
ENST00000443831.1
LDL receptor related protein 2
chr6_-_89217339 2.22 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr12_-_107761113 2.19 ENST00000228437.10
PR/SET domain 4
chr5_-_157575767 2.18 ENST00000257527.9
ADAM metallopeptidase domain 19
chr9_-_72365198 2.15 ENST00000376962.10
ENST00000376960.8
zinc finger AN1-type containing 5
chr17_+_59565598 2.12 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DEAH-box helicase 40
chr3_-_197298092 2.11 ENST00000392382.6
discs large MAGUK scaffold protein 1
chr15_-_78811415 2.09 ENST00000388820.5
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr13_-_39038039 2.08 ENST00000625998.2
ENST00000352251.8
proline and serine rich 1
chr2_+_69013414 2.06 ENST00000681816.1
ENST00000482235.2
ANTXR cell adhesion molecule 1
chr12_+_55931148 2.05 ENST00000549629.5
ENST00000555218.5
ENST00000331886.10
diacylglycerol kinase alpha
chr1_-_37595927 1.98 ENST00000373062.8
G protein nucleolar 2
chr2_-_17800195 1.98 ENST00000402989.5
ENST00000428868.1
structural maintenance of chromosomes 6
chr19_-_40285395 1.97 ENST00000424901.5
ENST00000578123.5
AKT serine/threonine kinase 2
chr1_+_99646025 1.97 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr6_-_33580229 1.95 ENST00000374467.4
ENST00000442998.6
ENST00000360661.9
BCL2 antagonist/killer 1
chr14_-_23155302 1.93 ENST00000529705.6
solute carrier family 7 member 8
chr8_+_30095400 1.93 ENST00000321250.13
ENST00000518001.1
ENST00000520682.5
ENST00000442880.6
ENST00000523116.5
leptin receptor overlapping transcript like 1
chr13_+_75760659 1.91 ENST00000526202.5
ENST00000465261.6
LIM domain 7
chr7_-_151814668 1.88 ENST00000651764.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr6_+_95577465 1.88 ENST00000369293.6
ENST00000683151.1
ENST00000358812.9
mannosidase endo-alpha
chr2_+_69013170 1.87 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr2_-_37324826 1.87 ENST00000234179.8
protein kinase D3
chr9_+_113463697 1.86 ENST00000317613.10
regulator of G protein signaling 3
chr1_-_6419903 1.84 ENST00000377836.8
ENST00000487437.5
ENST00000489730.1
ENST00000377834.8
hes family bHLH transcription factor 2
chr5_+_132257670 1.84 ENST00000253754.8
ENST00000379018.7
PDZ and LIM domain 4
chr6_+_20403679 1.84 ENST00000535432.2
E2F transcription factor 3
chr14_+_39175221 1.83 ENST00000556530.1
ENST00000216832.9
pinin, desmosome associated protein
chr2_+_69013282 1.80 ENST00000409829.7
ANTXR cell adhesion molecule 1
chr17_-_41350824 1.79 ENST00000007735.4
keratin 33A
chr19_-_11339573 1.79 ENST00000222120.8
RAB3D, member RAS oncogene family
chr3_-_168095344 1.78 ENST00000309027.4
golgi integral membrane protein 4
chr2_+_233712905 1.77 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr13_+_75760431 1.77 ENST00000321797.12
LIM domain 7
chr7_-_151814636 1.75 ENST00000652047.1
ENST00000650858.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr8_-_69833338 1.72 ENST00000524945.5
solute carrier organic anion transporter family member 5A1
chr15_+_78438199 1.72 ENST00000258886.13
iron responsive element binding protein 2
chr18_+_6729698 1.72 ENST00000383472.9
Rho GTPase activating protein 28
chr1_-_93614091 1.69 ENST00000370247.7
BCAR3 adaptor protein, NSP family member
chr1_-_53838276 1.69 ENST00000371429.4
NDC1 transmembrane nucleoporin
chr13_-_71867192 1.69 ENST00000611519.4
ENST00000620444.4
ENST00000613252.5
dachshund family transcription factor 1
chr11_-_10808304 1.66 ENST00000532082.6
eukaryotic translation initiation factor 4 gamma 2
chr2_+_190408324 1.62 ENST00000417958.5
ENST00000432036.5
ENST00000392328.6
major facilitator superfamily domain containing 6
chrX_+_70268324 1.56 ENST00000307959.9
ENST00000620997.4
ENST00000480877.6
arrestin 3
chr11_-_65614195 1.54 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr2_-_39121000 1.51 ENST00000402219.8
SOS Ras/Rac guanine nucleotide exchange factor 1
chr17_-_39864126 1.50 ENST00000351680.7
ENST00000346243.7
ENST00000350532.7
ENST00000467757.5
ENST00000439016.2
IKAROS family zinc finger 3
chr4_+_77157189 1.47 ENST00000316355.10
ENST00000502280.5
cyclin G2
chr15_+_50182188 1.45 ENST00000267842.10
solute carrier family 27 member 2
chr5_-_157575741 1.45 ENST00000517905.1
ADAM metallopeptidase domain 19
chrX_-_40097403 1.42 ENST00000397354.7
BCL6 corepressor
chr4_+_112231748 1.41 ENST00000274000.10
ENST00000309703.10
adaptor related protein complex 1 associated regulatory protein
chr10_+_52314272 1.40 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr5_+_43603163 1.38 ENST00000660752.1
ENST00000654405.1
ENST00000344920.9
ENST00000657172.1
ENST00000512996.6
ENST00000671668.1
nicotinamide nucleotide transhydrogenase
chr2_+_169066994 1.33 ENST00000357546.6
ENST00000432060.6
dehydrogenase/reductase 9
chr2_-_240896144 1.33 ENST00000388934.5
mab-21 like 4
chr10_+_69801874 1.33 ENST00000357811.8
collagen type XIII alpha 1 chain
chr11_-_119729158 1.32 ENST00000264025.8
nectin cell adhesion molecule 1
chr8_+_22161655 1.30 ENST00000318561.7
surfactant protein C
chr17_-_39864140 1.29 ENST00000623724.3
ENST00000439167.6
ENST00000377945.7
ENST00000394189.6
ENST00000377944.7
ENST00000377958.6
ENST00000535189.5
ENST00000377952.6
IKAROS family zinc finger 3
chr17_-_41369807 1.28 ENST00000251646.8
keratin 33B
chr9_-_35650902 1.27 ENST00000259608.8
ENST00000618781.1
signaling threshold regulating transmembrane adaptor 1
chr17_+_74432079 1.27 ENST00000392627.7
ENST00000392628.7
ENST00000582473.2
G protein-coupled receptor class C group 5 member C
chr14_+_74763308 1.23 ENST00000325680.12
ENST00000552421.5
YLP motif containing 1
chr4_-_122621011 1.23 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr22_-_38084093 1.21 ENST00000681075.1
solute carrier family 16 member 8
chr12_+_54008961 1.21 ENST00000040584.6
homeobox C8
chr7_+_120988683 1.21 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr2_+_69013337 1.18 ENST00000463335.2
ANTXR cell adhesion molecule 1
chr8_-_42501224 1.17 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr19_-_40285277 1.14 ENST00000579047.5
ENST00000392038.7
AKT serine/threonine kinase 2
chr3_-_197298000 1.12 ENST00000664991.1
discs large MAGUK scaffold protein 1
chr14_-_20454741 1.11 ENST00000206542.9
ENST00000553640.3
O-sialoglycoprotein endopeptidase
chr3_-_149221811 1.08 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr3_+_183635605 1.08 ENST00000493074.1
ENST00000437402.5
ENST00000454495.6
ENST00000473045.5
ENST00000468101.5
ENST00000427201.2
ENST00000482138.1
ENST00000454652.6
ENST00000242810.11
kelch like family member 24
chr2_+_32063533 1.07 ENST00000315285.9
spastin
chr16_+_2770911 1.05 ENST00000570539.1
serine/arginine repetitive matrix 2
chr3_+_141387801 1.05 ENST00000514251.5
zinc finger and BTB domain containing 38
chr3_+_52779916 1.02 ENST00000537050.5
inter-alpha-trypsin inhibitor heavy chain 1
chr2_-_207167220 1.02 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr10_+_113553039 0.99 ENST00000351270.4
hyaluronan binding protein 2
chr5_-_59039454 0.98 ENST00000358923.10
phosphodiesterase 4D
chr21_-_32771712 0.97 ENST00000331923.9
PAX3 and PAX7 binding protein 1
chr16_-_73048104 0.97 ENST00000268489.10
zinc finger homeobox 3
chr12_-_48570046 0.94 ENST00000301046.6
ENST00000549817.1
lactalbumin alpha
chr8_+_22161788 0.94 ENST00000521315.5
ENST00000437090.6
ENST00000679463.1
ENST00000520605.5
ENST00000522109.5
ENST00000524255.5
ENST00000523296.1
surfactant protein C
chr3_-_160565433 0.93 ENST00000483437.2
ENST00000678765.1
karyopherin subunit alpha 4
chr2_+_11539833 0.93 ENST00000263834.9
growth regulating estrogen receptor binding 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.3 45.1 GO:0033606 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
4.0 15.9 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
3.3 29.3 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
2.5 7.4 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
2.4 7.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
1.9 9.6 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.5 4.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.4 4.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
1.2 11.1 GO:0001661 conditioned taste aversion(GO:0001661)
1.2 21.2 GO:0017121 phospholipid scrambling(GO:0017121)
1.1 3.2 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
1.0 3.1 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
1.0 9.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.9 3.6 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.9 6.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.9 5.2 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.8 2.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.8 2.4 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.6 1.9 GO:0002339 B cell selection(GO:0002339)
0.6 3.8 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.6 3.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.6 2.3 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.6 2.3 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.5 3.3 GO:0060368 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.5 4.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.5 2.5 GO:0007386 compartment pattern specification(GO:0007386)
0.5 2.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 1.4 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996)
0.5 5.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.4 1.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.4 0.4 GO:0060197 cloacal septation(GO:0060197)
0.4 17.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.4 1.3 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.4 1.3 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.4 7.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 4.6 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.4 2.1 GO:0006740 NADPH regeneration(GO:0006740)
0.4 2.4 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.4 9.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.4 2.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 2.4 GO:0044211 CTP salvage(GO:0044211)
0.4 2.4 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.4 3.5 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.4 1.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 3.3 GO:0031936 DNA replication-dependent nucleosome assembly(GO:0006335) negative regulation of chromatin silencing(GO:0031936) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 1.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.4 1.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.3 1.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 2.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.3 1.5 GO:1904693 midbrain morphogenesis(GO:1904693)
0.3 3.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.3 5.8 GO:0061436 establishment of skin barrier(GO:0061436)
0.3 4.7 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.3 0.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 6.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 2.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 1.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 3.3 GO:0038203 TORC2 signaling(GO:0038203)
0.2 9.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 1.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 9.6 GO:0048745 smooth muscle tissue development(GO:0048745)
0.2 3.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 4.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 7.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 2.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 1.9 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 4.0 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.2 3.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2 1.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 17.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 3.5 GO:0015671 oxygen transport(GO:0015671)
0.2 18.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 3.6 GO:0006853 carnitine shuttle(GO:0006853)
0.2 1.3 GO:1902414 protein localization to cell junction(GO:1902414)
0.2 2.0 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.8 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 4.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 4.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 7.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 3.6 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.1 1.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 2.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 3.2 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 1.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 2.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 4.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 2.3 GO:0042953 vitamin D metabolic process(GO:0042359) lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.8 GO:0043589 skin morphogenesis(GO:0043589)
0.1 4.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 2.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 14.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 9.5 GO:0070268 cornification(GO:0070268)
0.1 3.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 2.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.5 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 1.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.6 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 5.9 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 1.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 12.3 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.1 1.1 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.6 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.9 GO:0015695 organic cation transport(GO:0015695)
0.1 3.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 3.9 GO:0014823 response to activity(GO:0014823)
0.0 0.3 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 1.1 GO:0006825 copper ion transport(GO:0006825)
0.0 1.3 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 3.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.6 GO:0031424 keratinization(GO:0031424)
0.0 15.7 GO:0042493 response to drug(GO:0042493)
0.0 2.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 1.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.0 0.4 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 1.5 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.3 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0008623 CHRAC(GO:0008623)
2.2 6.7 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.9 45.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.9 9.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
1.4 11.1 GO:0035976 AP1 complex(GO:0035976)
1.0 5.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.9 34.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.9 6.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.9 4.5 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.9 4.4 GO:0031523 Myb complex(GO:0031523)
0.5 2.0 GO:0035061 Smc5-Smc6 complex(GO:0030915) interchromatin granule(GO:0035061)
0.5 7.7 GO:0045120 pronucleus(GO:0045120)
0.4 13.3 GO:0071564 npBAF complex(GO:0071564)
0.4 4.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3 2.8 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.3 2.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 1.7 GO:0005816 spindle pole body(GO:0005816)
0.3 2.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.3 6.5 GO:0042588 zymogen granule(GO:0042588)
0.2 3.5 GO:0005833 hemoglobin complex(GO:0005833)
0.2 1.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 1.3 GO:0032584 growth cone membrane(GO:0032584)
0.2 0.7 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 9.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 5.5 GO:0032982 myosin filament(GO:0032982)
0.2 3.3 GO:0031932 TORC2 complex(GO:0031932)
0.2 2.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.2 3.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 18.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 3.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 4.0 GO:0005685 U1 snRNP(GO:0005685)
0.1 5.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 3.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 2.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 16.5 GO:0016605 PML body(GO:0016605)
0.1 1.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.5 GO:0031905 early endosome lumen(GO:0031905)
0.1 4.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.3 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.9 GO:0030057 desmosome(GO:0030057)
0.1 1.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 17.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 9.0 GO:0005882 intermediate filament(GO:0005882)
0.1 4.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 3.3 GO:0001772 immunological synapse(GO:0001772)
0.1 3.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 8.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 3.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.3 GO:0031526 brush border membrane(GO:0031526)
0.0 4.1 GO:0005643 nuclear pore(GO:0005643)
0.0 7.7 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 2.2 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 3.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 12.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 8.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.9 GO:0034399 nuclear periphery(GO:0034399)
0.0 2.1 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 3.3 GO:0042383 sarcolemma(GO:0042383)
0.0 9.7 GO:0005925 focal adhesion(GO:0005925)
0.0 2.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 6.0 GO:0016607 nuclear speck(GO:0016607)
0.0 3.3 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 6.1 GO:0005813 centrosome(GO:0005813)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.9 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
3.7 29.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
2.4 7.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
1.3 9.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
1.3 21.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.3 5.2 GO:0033677 DNA/RNA helicase activity(GO:0033677)
1.3 3.8 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.2 45.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.0 4.0 GO:0002046 opsin binding(GO:0002046)
0.9 4.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.9 17.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.8 4.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.8 3.2 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.8 2.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.8 2.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.7 7.4 GO:0070878 primary miRNA binding(GO:0070878)
0.7 21.2 GO:0070410 co-SMAD binding(GO:0070410)
0.7 3.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.6 1.9 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.6 2.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.6 12.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.6 2.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.5 9.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 5.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4 3.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 1.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 4.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 2.4 GO:0004849 uridine kinase activity(GO:0004849)
0.3 3.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 4.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 4.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 8.2 GO:0070064 proline-rich region binding(GO:0070064)
0.3 8.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 2.3 GO:0048495 Roundabout binding(GO:0048495)
0.3 4.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 1.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 0.9 GO:0004461 lactose synthase activity(GO:0004461)
0.2 1.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 3.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 11.1 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 13.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 1.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2 1.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 3.1 GO:0097016 L27 domain binding(GO:0097016)
0.2 7.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 6.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.9 GO:0019534 toxin transporter activity(GO:0019534)
0.1 1.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.9 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 2.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 3.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 2.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.4 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.4 GO:0035198 miRNA binding(GO:0035198)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 2.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 14.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 1.9 GO:0051400 BH domain binding(GO:0051400)
0.1 1.3 GO:0046790 virion binding(GO:0046790)
0.1 1.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 4.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 2.9 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 3.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 18.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 9.6 GO:0005518 collagen binding(GO:0005518)
0.1 2.4 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.8 GO:0031489 myosin V binding(GO:0031489)
0.1 1.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 13.1 GO:0001047 core promoter binding(GO:0001047)
0.1 2.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 3.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 1.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 5.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 2.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 3.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 3.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 2.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 3.9 GO:0008201 heparin binding(GO:0008201)
0.0 2.1 GO:0050661 NADP binding(GO:0050661)
0.0 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.6 GO:0042393 histone binding(GO:0042393)
0.0 4.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 7.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 1.0 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 3.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 6.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 9.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 15.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 3.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 5.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 14.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 4.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 4.0 PID CONE PATHWAY Visual signal transduction: Cones
0.2 21.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 6.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 10.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 4.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 11.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 4.0 PID MYC PATHWAY C-MYC pathway
0.1 5.1 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 3.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 4.9 PID FOXO PATHWAY FoxO family signaling
0.1 3.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 4.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 3.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 8.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.9 PID TNF PATHWAY TNF receptor signaling pathway
0.0 14.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.8 PID E2F PATHWAY E2F transcription factor network
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 3.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 19.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.4 11.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 21.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 29.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.3 3.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.3 3.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 7.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 6.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 3.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 4.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 32.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.2 3.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 4.7 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.2 4.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 3.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 4.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 18.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 9.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 15.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 3.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 4.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 5.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 4.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.7 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 2.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 2.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 3.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 5.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis