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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TCF7L2

Z-value: 0.55

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Transcription factors associated with TCF7L2

Gene Symbol Gene ID Gene Info
TCF7L2
ENSG00000148737.17 TCF7L2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L2hg38_v1_chr10_+_112950757_1129509160.274.9e-05Click!

Activity profile of TCF7L2 motif

Sorted Z-values of TCF7L2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_114257800 12.53 ENST00000535401.5
NNMT
nicotinamide N-methyltransferase
chr2_-_55917699 12.23 ENST00000634374.1
EFEMP1
EGF containing fibulin extracellular matrix protein 1
chr5_-_16936231 10.98 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
MYO10
myosin X
chr17_+_1771688 8.17 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin family F member 1
chr2_+_200440649 7.51 ENST00000366118.2
SPATS2L
spermatogenesis associated serine rich 2 like
chr6_-_11779606 6.92 ENST00000506810.1
ADTRP
androgen dependent TFPI regulating protein
chr7_+_94394886 6.87 ENST00000297268.11
ENST00000620463.1
COL1A2
collagen type I alpha 2 chain
chr11_+_69641146 6.46 ENST00000227507.3
ENST00000536559.1
CCND1
cyclin D1
chr16_+_72063226 6.21 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
HPR
haptoglobin-related protein
chr5_+_141417659 5.92 ENST00000398594.4
PCDHGB7
protocadherin gamma subfamily B, 7
chrX_-_10620419 5.91 ENST00000380782.6
MID1
midline 1
chr6_+_31946086 5.74 ENST00000425368.7
CFB
complement factor B
chrX_-_10620534 5.73 ENST00000317552.9
MID1
midline 1
chr10_+_7703340 4.94 ENST00000429820.5
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr5_+_102865805 4.88 ENST00000346918.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr16_+_72054477 4.87 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
HP
haptoglobin
chr10_+_52314272 4.86 ENST00000373970.4
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr8_-_118951876 4.82 ENST00000297350.9
TNFRSF11B
TNF receptor superfamily member 11b
chr15_+_43692886 4.71 ENST00000434505.5
ENST00000411750.5
CKMT1A
creatine kinase, mitochondrial 1A
chr10_+_7703300 4.66 ENST00000358415.9
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr13_+_75760659 4.41 ENST00000526202.5
ENST00000465261.6
LMO7
LIM domain 7
chr13_+_75760431 4.11 ENST00000321797.12
LMO7
LIM domain 7
chr15_+_43593054 4.07 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
CKMT1B
creatine kinase, mitochondrial 1B
chr17_-_40100569 3.95 ENST00000246672.4
NR1D1
nuclear receptor subfamily 1 group D member 1
chr12_-_12338674 3.90 ENST00000545735.1
MANSC1
MANSC domain containing 1
chrX_+_54809060 3.89 ENST00000396224.1
MAGED2
MAGE family member D2
chr10_+_99782628 3.69 ENST00000648689.1
ENST00000647814.1
ABCC2
ATP binding cassette subfamily C member 2
chr2_+_233712905 3.63 ENST00000373414.4
UGT1A5
UDP glucuronosyltransferase family 1 member A5
chr6_-_32178080 3.62 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr2_+_69013414 3.50 ENST00000681816.1
ENST00000482235.2
ANTXR1
ANTXR cell adhesion molecule 1
chr15_+_64460728 3.41 ENST00000416172.1
ZNF609
zinc finger protein 609
chr1_-_93614091 3.36 ENST00000370247.7
BCAR3
BCAR3 adaptor protein, NSP family member
chr4_+_112860981 3.35 ENST00000671704.1
ANK2
ankyrin 2
chr4_+_112860912 3.33 ENST00000671951.1
ANK2
ankyrin 2
chr10_+_69801874 3.33 ENST00000357811.8
COL13A1
collagen type XIII alpha 1 chain
chr1_-_110390989 3.30 ENST00000369779.9
ENST00000472422.6
SLC16A4
solute carrier family 16 member 4
chr10_-_73591330 3.30 ENST00000451492.5
ENST00000681793.1
ENST00000680396.1
ENST00000413442.5
USP54
ubiquitin specific peptidase 54
chr16_-_73048104 3.23 ENST00000268489.10
ZFHX3
zinc finger homeobox 3
chr2_+_69013170 3.17 ENST00000303714.9
ANTXR1
ANTXR cell adhesion molecule 1
chr4_+_112861053 3.14 ENST00000672221.1
ANK2
ankyrin 2
chr5_-_135954962 3.10 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
LECT2
leukocyte cell derived chemotaxin 2
chr13_-_35855627 3.05 ENST00000379893.5
DCLK1
doublecortin like kinase 1
chr1_+_16004228 3.03 ENST00000329454.2
SRARP
steroid receptor associated and regulated protein
chr5_-_161546671 2.99 ENST00000517547.5
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr2_+_69013282 2.93 ENST00000409829.7
ANTXR1
ANTXR cell adhesion molecule 1
chrX_+_123860262 2.91 ENST00000355640.3
XIAP
X-linked inhibitor of apoptosis
chrX_+_153494970 2.86 ENST00000331595.9
ENST00000431891.1
BGN
biglycan
chr10_-_86957582 2.85 ENST00000372027.10
MMRN2
multimerin 2
chr2_+_69013379 2.81 ENST00000409349.7
ANTXR1
ANTXR cell adhesion molecule 1
chr4_-_138242325 2.81 ENST00000280612.9
SLC7A11
solute carrier family 7 member 11
chr17_-_40937445 2.77 ENST00000436344.7
ENST00000485751.1
KRT23
keratin 23
chr17_-_40937641 2.72 ENST00000209718.8
KRT23
keratin 23
chr13_+_101489940 2.66 ENST00000376162.7
ITGBL1
integrin subunit beta like 1
chr10_+_69801892 2.63 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
COL13A1
collagen type XIII alpha 1 chain
chr5_+_132257670 2.63 ENST00000253754.8
ENST00000379018.7
PDLIM4
PDZ and LIM domain 4
chr6_-_166167832 2.63 ENST00000366876.7
TBXT
T-box transcription factor T
chr6_-_112254647 2.61 ENST00000455073.1
ENST00000522006.5
ENST00000519932.5
LAMA4
laminin subunit alpha 4
chr9_-_23826299 2.59 ENST00000380117.5
ELAVL2
ELAV like RNA binding protein 2
chr1_-_110391041 2.57 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
SLC16A4
solute carrier family 16 member 4
chr4_-_108762964 2.57 ENST00000512646.5
ENST00000411864.6
ENST00000296486.8
ENST00000510706.5
ETNPPL
ethanolamine-phosphate phospho-lyase
chr5_-_161546708 2.56 ENST00000393959.6
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr13_-_35855758 2.54 ENST00000615680.4
DCLK1
doublecortin like kinase 1
chr7_+_27242796 2.53 ENST00000496902.7
EVX1
even-skipped homeobox 1
chr5_-_59039454 2.52 ENST00000358923.10
PDE4D
phosphodiesterase 4D
chr4_-_74099187 2.52 ENST00000508487.3
CXCL2
C-X-C motif chemokine ligand 2
chr7_+_138076453 2.40 ENST00000242375.8
ENST00000411726.6
AKR1D1
aldo-keto reductase family 1 member D1
chr6_-_112254485 2.26 ENST00000521398.5
ENST00000424408.6
ENST00000243219.7
LAMA4
laminin subunit alpha 4
chr8_-_94208548 2.20 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
CDH17
cadherin 17
chr5_-_176388563 2.19 ENST00000509257.1
ENST00000616685.1
ENST00000614830.5
NOP16
NOP16 nucleolar protein
chr12_+_54033026 2.15 ENST00000312492.3
HOXC5
homeobox C5
chr3_+_29281552 2.14 ENST00000452462.5
ENST00000456853.1
RBMS3
RNA binding motif single stranded interacting protein 3
chr18_+_48539017 2.13 ENST00000256413.8
CTIF
cap binding complex dependent translation initiation factor
chr19_-_40285277 2.13 ENST00000579047.5
ENST00000392038.7
AKT2
AKT serine/threonine kinase 2
chr2_-_88128049 2.13 ENST00000393750.3
ENST00000295834.8
FABP1
fatty acid binding protein 1
chr17_-_69141878 2.11 ENST00000590645.1
ENST00000284425.7
ABCA6
ATP binding cassette subfamily A member 6
chr18_+_48539112 2.02 ENST00000382998.8
CTIF
cap binding complex dependent translation initiation factor
chr8_-_142879820 2.02 ENST00000377675.3
ENST00000517471.5
ENST00000292427.10
CYP11B1
cytochrome P450 family 11 subfamily B member 1
chr17_+_44846318 2.01 ENST00000591513.5
HIGD1B
HIG1 hypoxia inducible domain family member 1B
chr7_+_100015572 1.99 ENST00000535170.5
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr2_+_11539833 1.99 ENST00000263834.9
GREB1
growth regulating estrogen receptor binding 1
chr5_+_161850597 1.97 ENST00000634335.1
ENST00000635880.1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chrX_-_43973382 1.96 ENST00000642620.1
ENST00000647044.1
NDP
norrin cystine knot growth factor NDP
chr2_+_69013337 1.95 ENST00000463335.2
ANTXR1
ANTXR cell adhesion molecule 1
chr9_-_74887720 1.91 ENST00000449912.6
TRPM6
transient receptor potential cation channel subfamily M member 6
chr2_+_112911159 1.90 ENST00000263326.8
IL37
interleukin 37
chr3_-_134374439 1.88 ENST00000513145.1
ENST00000249883.10
ENST00000422605.6
AMOTL2
angiomotin like 2
chr7_+_100015588 1.88 ENST00000324306.11
ENST00000426572.5
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr5_+_55160161 1.88 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
GPX8
glutathione peroxidase 8 (putative)
chr5_-_161546970 1.75 ENST00000675303.1
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr10_+_113553039 1.73 ENST00000351270.4
HABP2
hyaluronan binding protein 2
chr14_+_20768393 1.69 ENST00000326783.4
EDDM3B
epididymal protein 3B
chrX_+_47078434 1.68 ENST00000397180.6
RGN
regucalcin
chr6_-_11778781 1.66 ENST00000414691.8
ENST00000229583.9
ADTRP
androgen dependent TFPI regulating protein
chr9_-_74887914 1.62 ENST00000360774.6
TRPM6
transient receptor potential cation channel subfamily M member 6
chr14_-_52791597 1.62 ENST00000216410.8
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr14_-_52791462 1.60 ENST00000650397.1
ENST00000554230.5
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr3_+_156120572 1.59 ENST00000389636.9
ENST00000490337.6
KCNAB1
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr12_+_1629197 1.57 ENST00000397196.7
WNT5B
Wnt family member 5B
chr10_+_47300174 1.56 ENST00000580279.2
GDF10
growth differentiation factor 10
chr7_-_75823355 1.56 ENST00000416943.1
CCL24
C-C motif chemokine ligand 24
chr2_+_172821575 1.55 ENST00000397087.7
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr2_+_172860038 1.55 ENST00000538974.5
ENST00000540783.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr7_-_27174253 1.54 ENST00000613671.1
HOXA10
homeobox A10
chr14_+_74348440 1.54 ENST00000256362.5
VRTN
vertebrae development associated
chr1_-_11848345 1.53 ENST00000376476.1
NPPA
natriuretic peptide A
chr19_-_40285395 1.53 ENST00000424901.5
ENST00000578123.5
AKT2
AKT serine/threonine kinase 2
chr5_-_24644968 1.53 ENST00000264463.8
CDH10
cadherin 10
chr19_-_18606779 1.49 ENST00000684169.1
ENST00000392386.8
CRLF1
cytokine receptor like factor 1
chr17_-_47957824 1.48 ENST00000300557.3
PRR15L
proline rich 15 like
chrX_+_47078380 1.48 ENST00000352078.8
RGN
regucalcin
chr1_+_99646025 1.46 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
PALMD
palmdelphin
chr10_-_102432565 1.45 ENST00000369937.5
CUEDC2
CUE domain containing 2
chr11_-_35360050 1.44 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
SLC1A2
solute carrier family 1 member 2
chr1_+_16367088 1.44 ENST00000471507.5
ENST00000401089.3
ENST00000401088.9
ENST00000492354.1
SZRD1
SUZ RNA binding domain containing 1
chr20_+_59300547 1.42 ENST00000644821.1
EDN3
endothelin 3
chr11_-_62707413 1.42 ENST00000360796.10
ENST00000449636.6
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr7_-_151814668 1.42 ENST00000651764.1
PRKAG2
protein kinase AMP-activated non-catalytic subunit gamma 2
chr11_-_62707581 1.41 ENST00000684475.1
ENST00000683296.1
ENST00000684067.1
ENST00000682223.1
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chrX_+_47078330 1.40 ENST00000457380.5
RGN
regucalcin
chr15_-_55588337 1.38 ENST00000563719.4
PYGO1
pygopus family PHD finger 1
chr8_-_132111159 1.37 ENST00000673615.1
ENST00000434736.6
HHLA1
HERV-H LTR-associating 1
chr7_-_151814636 1.36 ENST00000652047.1
ENST00000650858.1
PRKAG2
protein kinase AMP-activated non-catalytic subunit gamma 2
chr1_-_109393197 1.36 ENST00000538502.5
ENST00000482236.5
SORT1
sortilin 1
chr4_+_95051671 1.32 ENST00000440890.7
BMPR1B
bone morphogenetic protein receptor type 1B
chrX_+_15507302 1.29 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr1_-_11847772 1.27 ENST00000376480.7
ENST00000610706.1
NPPA
natriuretic peptide A
chr5_+_67004618 1.25 ENST00000261569.11
ENST00000436277.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr15_-_89221558 1.24 ENST00000268125.10
RLBP1
retinaldehyde binding protein 1
chr6_-_112254555 1.23 ENST00000230538.12
ENST00000389463.9
ENST00000368638.5
ENST00000431543.6
ENST00000453937.2
LAMA4
laminin subunit alpha 4
chr16_+_19211157 1.23 ENST00000568433.1
SYT17
synaptotagmin 17
chr6_-_28252246 1.22 ENST00000377294.3
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr7_+_111091119 1.20 ENST00000308478.10
LRRN3
leucine rich repeat neuronal 3
chr5_-_149551381 1.15 ENST00000670598.1
ENST00000657001.1
ENST00000515768.6
ENST00000261798.10
ENST00000377843.8
CSNK1A1
casein kinase 1 alpha 1
chr18_-_26865732 1.15 ENST00000672188.1
AQP4
aquaporin 4
chr2_-_201071579 1.14 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
FAM126B
family with sequence similarity 126 member B
chr1_-_53838276 1.08 ENST00000371429.4
NDC1
NDC1 transmembrane nucleoporin
chr18_-_26865689 1.01 ENST00000675739.1
ENST00000383168.9
ENST00000672981.2
ENST00000578776.1
AQP4
aquaporin 4
chr7_-_80512041 1.00 ENST00000398291.4
GNAT3
G protein subunit alpha transducin 3
chr1_+_61952283 1.00 ENST00000307297.8
PATJ
PATJ crumbs cell polarity complex component
chr7_-_27174274 1.00 ENST00000283921.5
HOXA10
homeobox A10
chr14_-_64942783 0.99 ENST00000612794.1
GPX2
glutathione peroxidase 2
chr20_+_59300703 0.98 ENST00000395654.3
EDN3
endothelin 3
chr10_+_52128343 0.95 ENST00000672084.1
PRKG1
protein kinase cGMP-dependent 1
chr3_-_57165332 0.95 ENST00000296318.12
IL17RD
interleukin 17 receptor D
chr5_-_16742221 0.93 ENST00000505695.5
MYO10
myosin X
chr20_-_17531366 0.93 ENST00000377873.8
BFSP1
beaded filament structural protein 1
chr1_-_162023826 0.90 ENST00000294794.8
OLFML2B
olfactomedin like 2B
chr8_+_32721823 0.87 ENST00000539990.3
ENST00000519240.5
NRG1
neuregulin 1
chr14_+_32329341 0.87 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
AKAP6
A-kinase anchoring protein 6
chr6_-_25930611 0.86 ENST00000360488.7
SLC17A2
solute carrier family 17 member 2
chr5_+_175861628 0.86 ENST00000509837.5
CPLX2
complexin 2
chr20_-_57265738 0.85 ENST00000433911.1
BMP7
bone morphogenetic protein 7
chr16_+_50548387 0.85 ENST00000268459.6
NKD1
NKD inhibitor of WNT signaling pathway 1
chr6_-_25930678 0.85 ENST00000377850.8
SLC17A2
solute carrier family 17 member 2
chr7_+_111091006 0.84 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr20_+_59300402 0.84 ENST00000311585.11
ENST00000371028.6
EDN3
endothelin 3
chr9_-_127950716 0.83 ENST00000373084.8
FAM102A
family with sequence similarity 102 member A
chr12_+_70366277 0.82 ENST00000258111.5
KCNMB4
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr2_+_48568981 0.81 ENST00000394754.5
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr5_-_154478218 0.80 ENST00000231121.3
HAND1
heart and neural crest derivatives expressed 1
chr20_+_59300589 0.78 ENST00000337938.7
ENST00000371025.7
EDN3
endothelin 3
chr4_-_122621011 0.77 ENST00000611104.2
ENST00000648588.1
IL21
interleukin 21
chr17_+_81712236 0.76 ENST00000545862.5
ENST00000350690.10
ENST00000331531.9
SLC25A10
solute carrier family 25 member 10
chr12_-_52385649 0.73 ENST00000257951.3
KRT84
keratin 84
chr12_-_48570046 0.73 ENST00000301046.6
ENST00000549817.1
LALBA
lactalbumin alpha
chr14_+_32329256 0.72 ENST00000280979.9
AKAP6
A-kinase anchoring protein 6
chr19_-_51082883 0.69 ENST00000650543.2
KLK14
kallikrein related peptidase 14
chr10_-_102419934 0.61 ENST00000406432.5
PSD
pleckstrin and Sec7 domain containing
chr12_+_8914525 0.55 ENST00000543824.5
PHC1
polyhomeotic homolog 1
chr3_+_137764296 0.55 ENST00000306087.3
SOX14
SRY-box transcription factor 14
chr17_-_41350824 0.55 ENST00000007735.4
KRT33A
keratin 33A
chr7_+_27242700 0.51 ENST00000222761.7
EVX1
even-skipped homeobox 1
chr13_-_27969295 0.49 ENST00000381020.8
CDX2
caudal type homeobox 2
chr3_-_177196451 0.47 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1XR1
TBL1X receptor 1
chr15_-_93089192 0.44 ENST00000329082.11
RGMA
repulsive guidance molecule BMP co-receptor a
chr1_-_6419903 0.42 ENST00000377836.8
ENST00000487437.5
ENST00000489730.1
ENST00000377834.8
HES2
hes family bHLH transcription factor 2
chr10_-_60141004 0.41 ENST00000355288.6
ANK3
ankyrin 3
chr5_-_176388629 0.39 ENST00000619979.4
ENST00000621444.4
NOP16
NOP16 nucleolar protein
chr6_+_63571702 0.38 ENST00000672924.1
PTP4A1
protein tyrosine phosphatase 4A1
chr1_-_19923617 0.35 ENST00000375116.3
PLA2G2E
phospholipase A2 group IIE
chr12_-_23584600 0.34 ENST00000396007.6
SOX5
SRY-box transcription factor 5
chr7_-_106285898 0.33 ENST00000424768.2
ENST00000681255.1
NAMPT
nicotinamide phosphoribosyltransferase
chrX_-_32155462 0.30 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
DMD
dystrophin
chrX_-_47145035 0.28 ENST00000276062.8
NDUFB11
NADH:ubiquinone oxidoreductase subunit B11
chr1_+_147541491 0.26 ENST00000683836.1
ENST00000234739.8
BCL9
BCL9 transcription coactivator
chr7_-_139777986 0.26 ENST00000406875.8
HIPK2
homeodomain interacting protein kinase 2
chr10_-_102419693 0.26 ENST00000611678.4
PSD
pleckstrin and Sec7 domain containing
chr3_+_141368497 0.23 ENST00000321464.7
ZBTB38
zinc finger and BTB domain containing 38
chr18_+_10454584 0.22 ENST00000355285.10
APCDD1
APC down-regulated 1
chr9_+_133534697 0.22 ENST00000651351.2
ADAMTSL2
ADAMTS like 2
chr18_+_32190015 0.21 ENST00000581447.1
MEP1B
meprin A subunit beta
chr1_-_160579439 0.21 ENST00000368054.8
ENST00000368048.7
ENST00000311224.8
ENST00000368051.3
ENST00000534968.5
CD84
CD84 molecule
chr10_+_103245887 0.21 ENST00000441178.2
RPEL1
ribulose-5-phosphate-3-epimerase like 1
chr6_+_151809105 0.17 ENST00000427531.6
ESR1
estrogen receptor 1
chr2_+_203867764 0.16 ENST00000648405.2
CTLA4
cytotoxic T-lymphocyte associated protein 4
chr5_+_171419635 0.15 ENST00000274625.6
FGF18
fibroblast growth factor 18
chr8_-_6926066 0.12 ENST00000297436.3
DEFA6
defensin alpha 6
chr5_-_149551168 0.09 ENST00000515748.2
ENST00000606719.6
CSNK1A1
casein kinase 1 alpha 1
chr2_+_227813834 0.08 ENST00000358813.5
ENST00000409189.7
CCL20
C-C motif chemokine ligand 20
chr2_-_232776555 0.08 ENST00000438786.1
ENST00000233826.4
ENST00000409779.1
KCNJ13
potassium inwardly rectifying channel subfamily J member 13

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 14.4 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.7 12.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
1.6 4.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.6 4.9 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996)
1.3 4.0 GO:0060086 circadian temperature homeostasis(GO:0060086)
1.2 3.7 GO:0016999 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
1.2 4.9 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.2 3.7 GO:0097473 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
1.2 8.2 GO:0071279 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
1.1 4.6 GO:1903627 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
1.0 3.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
1.0 9.8 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.8 11.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.8 2.4 GO:0030573 bile acid catabolic process(GO:0030573)
0.8 12.9 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.7 2.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.7 4.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.7 2.9 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.7 4.9 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.6 3.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.6 3.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.6 6.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.6 4.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.6 3.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.5 6.9 GO:0043589 skin morphogenesis(GO:0043589)
0.4 2.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 9.3 GO:0071420 cellular response to histamine(GO:0071420)
0.3 4.7 GO:0006600 creatine metabolic process(GO:0006600)
0.3 3.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 1.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.3 2.9 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.3 0.8 GO:0007525 somatic muscle development(GO:0007525)
0.3 2.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3 5.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 0.8 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.3 2.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 1.6 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.3 3.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.3 1.0 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.2 0.7 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2 0.9 GO:0072134 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme morphogenesis(GO:0072134) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) allantois development(GO:1905069)
0.2 2.0 GO:0035865 cellular response to potassium ion(GO:0035865)
0.2 0.8 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2 3.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.2 1.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.2 1.5 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 2.5 GO:0070307 lens fiber cell development(GO:0070307)
0.2 2.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 11.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 4.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 2.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.0 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 1.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 2.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 2.8 GO:0006853 carnitine shuttle(GO:0006853)
0.1 2.0 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 7.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 3.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 5.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 6.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.5 GO:0032196 transposition(GO:0032196)
0.1 2.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 1.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 2.2 GO:0006833 water transport(GO:0006833)
0.1 0.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.9 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.8 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.1 1.4 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.1 7.0 GO:0070268 cornification(GO:0070268)
0.1 1.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.5 GO:0060613 fat pad development(GO:0060613)
0.0 0.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 6.1 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 1.9 GO:0035329 hippo signaling(GO:0035329)
0.0 6.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0019323 pentose catabolic process(GO:0019323)
0.0 1.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 3.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.8 GO:0005513 detection of calcium ion(GO:0005513)
0.0 4.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 1.6 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 2.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 2.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.6 GO:0009649 entrainment of circadian clock(GO:0009649)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.2 4.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.8 26.6 GO:0031527 filopodium membrane(GO:0031527)
0.7 8.2 GO:0043203 axon hillock(GO:0043203)
0.5 6.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 1.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.4 2.1 GO:0045179 apical cortex(GO:0045179)
0.4 6.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.4 3.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.6 GO:1990635 proximal dendrite(GO:1990635)
0.2 9.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 1.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 10.2 GO:0043034 costamere(GO:0043034)
0.2 1.1 GO:0005816 spindle pole body(GO:0005816)
0.1 0.9 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 2.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 6.1 GO:0005605 basal lamina(GO:0005605)
0.1 6.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 6.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 13.9 GO:0072562 blood microparticle(GO:0072562)
0.1 25.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 6.9 GO:0005882 intermediate filament(GO:0005882)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.0 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 5.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 4.2 GO:0043204 perikaryon(GO:0043204)
0.0 4.0 GO:0043197 dendritic spine(GO:0043197)
0.0 5.6 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 5.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 2.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 3.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.0 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.6 11.1 GO:0030492 hemoglobin binding(GO:0030492)
1.5 11.9 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
1.2 4.9 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.1 4.6 GO:0004341 gluconolactonase activity(GO:0004341)
0.9 2.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.8 2.4 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.7 7.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.7 2.0 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.7 4.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.6 4.7 GO:0004111 creatine kinase activity(GO:0004111)
0.6 2.8 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.5 6.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 4.9 GO:0039706 co-receptor binding(GO:0039706)
0.4 2.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.4 1.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.4 1.6 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.3 1.5 GO:0004803 transposase activity(GO:0004803)
0.3 2.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 3.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 0.8 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 1.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 4.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.8 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 1.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 2.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 6.5 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.0 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 0.7 GO:0004461 lactose synthase activity(GO:0004461)
0.2 10.2 GO:0030507 spectrin binding(GO:0030507)
0.2 5.7 GO:0001848 complement binding(GO:0001848)
0.2 2.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 17.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 4.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 2.2 GO:0015250 water channel activity(GO:0015250)
0.1 1.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 5.6 GO:0030552 cAMP binding(GO:0030552)
0.1 5.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 9.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.5 GO:0005109 frizzled binding(GO:0005109)
0.1 0.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 3.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 9.1 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 2.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.2 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 1.6 GO:0070402 NADPH binding(GO:0070402)
0.1 2.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 13.9 GO:0051015 actin filament binding(GO:0051015)
0.0 4.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 6.0 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 3.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 3.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 3.3 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 3.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 5.6 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 1.7 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 5.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 14.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 6.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 12.8 NABA COLLAGENS Genes encoding collagen proteins
0.2 5.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 11.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 6.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 4.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 8.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 5.5 PID BMP PATHWAY BMP receptor signaling
0.1 2.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 15.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 17.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 3.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 4.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 2.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.9 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 3.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 5.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 8.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 6.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 3.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 2.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 12.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 2.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 4.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 3.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 11.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 5.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 4.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 4.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 6.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 5.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 4.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 5.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins