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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TFCP2

Z-value: 4.66

Motif logo

Transcription factors associated with TFCP2

Gene Symbol Gene ID Gene Info
ENSG00000135457.10 TFCP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2hg38_v1_chr12_-_51172779_511729120.194.8e-03Click!

Activity profile of TFCP2 motif

Sorted Z-values of TFCP2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr21_-_39349048 28.18 ENST00000380748.5
ENST00000380749.10
high mobility group nucleosome binding domain 1
chr2_-_61538180 21.31 ENST00000677150.1
ENST00000678182.1
ENST00000677928.1
ENST00000406957.5
exportin 1
chr2_-_61538313 20.83 ENST00000677803.1
ENST00000677239.1
ENST00000401558.7
exportin 1
chr2_-_61538290 20.20 ENST00000678790.1
exportin 1
chr4_-_173334385 19.91 ENST00000446922.6
high mobility group box 2
chr4_-_173334249 19.08 ENST00000506267.1
ENST00000296503.10
high mobility group box 2
chr2_-_61538516 16.82 ENST00000676771.1
ENST00000677814.1
ENST00000443240.5
ENST00000677556.1
ENST00000676553.1
exportin 1
chr14_+_93185304 16.77 ENST00000415050.3
transmembrane protein 251
chrX_+_119468436 15.93 ENST00000317881.9
solute carrier family 25 member 5
chr2_-_89160329 15.16 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr2_+_90021567 12.63 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr5_+_138179145 12.37 ENST00000508792.5
ENST00000504621.1
kinesin family member 20A
chr15_-_21742799 12.24 ENST00000622410.2
novel protein, identical to IGHV4-4
chr7_-_105522204 11.95 ENST00000356362.6
pseudouridine synthase 7
chr14_-_105940235 11.95 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr14_-_105863862 11.89 ENST00000488476.1
immunoglobulin heavy joining 5
chr7_-_105522264 11.87 ENST00000469408.6
pseudouridine synthase 7
chr5_+_138179093 11.65 ENST00000394894.8
kinesin family member 20A
chr6_+_138404206 11.02 ENST00000607197.6
ENST00000367697.7
heme binding protein 2
chr19_+_1071194 10.59 ENST00000543365.5
Rho GTPase activating protein 45
chr3_-_184248935 10.54 ENST00000446569.1
ENST00000397676.8
ALG3 alpha-1,3- mannosyltransferase
chr15_-_34343112 10.47 ENST00000557912.1
ENST00000328848.6
NOP10 ribonucleoprotein
chr9_-_127451395 10.41 ENST00000361436.10
ribosomal protein L12
chr22_+_22818994 10.31 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr1_+_44746401 10.12 ENST00000372217.5
kinesin family member 2C
chr8_-_63026179 10.05 ENST00000677919.1
gamma-glutamyl hydrolase
chr17_-_5439076 9.99 ENST00000225698.8
complement C1q binding protein
chr14_-_106277039 9.34 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr14_-_106422175 9.33 ENST00000390619.2
immunoglobulin heavy variable 4-39
chr6_+_142301926 9.24 ENST00000296932.13
ENST00000367609.8
adhesion G protein-coupled receptor G6
chr14_-_106639589 8.73 ENST00000390630.3
immunoglobulin heavy variable 4-61
chr3_-_113746218 8.36 ENST00000497255.1
ENST00000240922.8
ENST00000478020.1
ENST00000493900.5
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr14_-_106374129 8.35 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr10_+_74176537 8.28 ENST00000672394.1
adenosine kinase
chr1_+_26472405 8.15 ENST00000361427.6
high mobility group nucleosomal binding domain 2
chr6_-_31729260 8.07 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr2_+_199955539 7.73 ENST00000392290.5
matrix AAA peptidase interacting protein 1
chr13_-_41061373 7.59 ENST00000405737.2
E74 like ETS transcription factor 1
chr6_-_31729478 7.47 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chrX_-_53434341 7.43 ENST00000375298.4
ENST00000375304.9
ENST00000684692.1
ENST00000168216.11
hydroxysteroid 17-beta dehydrogenase 10
chr9_-_127451373 7.39 ENST00000536368.1
ribosomal protein L12
chr11_+_46381645 7.30 ENST00000617138.4
ENST00000395566.9
ENST00000395569.8
midkine
chr1_+_26472459 7.22 ENST00000619352.4
high mobility group nucleosomal binding domain 2
chr20_+_36461460 7.13 ENST00000482872.5
ENST00000495241.5
DLG associated protein 4
chrX_-_119791620 7.12 ENST00000361575.4
ribosomal protein L39
chr2_+_112645930 7.09 ENST00000272542.8
solute carrier family 20 member 1
chr6_-_31729785 6.97 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr1_+_28736927 6.96 ENST00000373812.8
ENST00000541996.5
ENST00000496288.5
YTH N6-methyladenosine RNA binding protein 2
chrX_+_152698767 6.96 ENST00000417212.5
ENST00000598245.2
ENST00000370278.4
MAGE family member A3
chr10_+_74176741 6.90 ENST00000673027.1
ENST00000372734.5
ENST00000541550.6
adenosine kinase
chr3_-_113746185 6.88 ENST00000616174.1
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr14_-_22982258 6.81 ENST00000555074.1
ENST00000361265.8
novel protein
ajuba LIM protein
chr7_-_7640009 6.73 ENST00000401447.1
replication protein A3
chr5_-_150289941 6.68 ENST00000682786.1
calcium/calmodulin dependent protein kinase II alpha
chr18_+_12308232 6.57 ENST00000590103.5
ENST00000591909.5
ENST00000586653.5
ENST00000317702.10
ENST00000592683.5
ENST00000590967.5
ENST00000591208.1
ENST00000591463.1
tubulin beta 6 class V
chr2_+_237486391 6.55 ENST00000429898.5
ENST00000410032.5
melanophilin
chr6_-_8102481 6.55 ENST00000502429.5
ENST00000429723.6
ENST00000379715.10
ENST00000507463.1
eukaryotic translation elongation factor 1 epsilon 1
chr15_-_22185402 6.50 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr11_+_46381698 6.49 ENST00000395565.5
midkine
chr10_-_93482326 6.38 ENST00000359263.9
myoferlin
chr9_-_21995301 6.38 ENST00000498628.6
cyclin dependent kinase inhibitor 2A
chr1_-_229508287 6.33 ENST00000261396.6
nucleoporin 133
chr3_+_36993798 6.21 ENST00000455445.6
ENST00000539477.6
ENST00000435176.5
ENST00000429117.5
ENST00000441265.6
mutL homolog 1
chr3_+_184315347 6.17 ENST00000424196.5
eukaryotic translation initiation factor 4 gamma 1
chr19_-_43527189 6.14 ENST00000292147.7
ENST00000600651.5
ETHE1 persulfide dioxygenase
chrX_-_152769677 6.13 ENST00000457643.1
ENST00000616035.4
ENST00000412733.1
ENST00000329342.9
MAGE family member A6
chr6_-_32666648 6.10 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
major histocompatibility complex, class II, DQ beta 1
chr11_+_46381753 6.10 ENST00000407067.1
midkine
chr8_-_140635617 6.07 ENST00000220592.10
argonaute RISC catalytic component 2
chr10_-_93482194 5.96 ENST00000358334.9
ENST00000371488.3
myoferlin
chr6_-_31730198 5.83 ENST00000375787.6
dimethylarginine dimethylaminohydrolase 2
chr2_-_151289613 5.72 ENST00000243346.10
N-myc and STAT interactor
chr18_+_58671517 5.64 ENST00000345724.7
MALT1 paracaspase
chr7_+_95485898 5.53 ENST00000428113.5
ankyrin repeat and SOCS box containing 4
chr1_-_11058839 5.33 ENST00000465788.1
spermidine synthase
chr10_+_13161543 5.31 ENST00000378714.8
ENST00000479669.5
ENST00000484800.6
minichromosome maintenance 10 replication initiation factor
chr3_-_150546403 5.29 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
stress associated endoplasmic reticulum protein 1
chr11_+_62881686 5.26 ENST00000536981.6
ENST00000539891.6
solute carrier family 3 member 2
chr1_-_50960230 5.26 ENST00000396153.7
Fas associated factor 1
chr4_-_2933947 5.24 ENST00000514800.5
major facilitator superfamily domain containing 10
chrX_+_154379336 5.23 ENST00000682114.1
emerin
chr17_-_5419647 5.05 ENST00000573584.6
nucleoporin 88
chrX_+_152714586 5.00 ENST00000331220.6
ENST00000370293.6
ENST00000423993.5
ENST00000447530.5
ENST00000682532.1
ENST00000458057.5
ENST00000422085.5
ENST00000453150.5
ENST00000409560.1
MAGE family member A2B
chr7_-_44573895 5.00 ENST00000258772.10
ENST00000431640.5
DEAD-box helicase 56
chrX_+_153179276 4.78 ENST00000356661.7
MAGE family member A1
chr11_+_2902258 4.60 ENST00000649076.2
ENST00000449793.6
solute carrier family 22 member 18
chr15_-_66386668 4.47 ENST00000568216.5
ENST00000562124.5
ENST00000570251.1
TIMELESS interacting protein
chr6_+_63211446 4.44 ENST00000370659.1
FKBP prolyl isomerase family member 1C
chr3_+_107522936 4.43 ENST00000415149.6
ENST00000402543.5
ENST00000325805.13
ENST00000427402.5
BBX high mobility group box domain containing
chr7_-_47582076 4.40 ENST00000311160.14
tensin 3
chr1_-_38859669 4.32 ENST00000373001.4
Ras related GTP binding C
chr14_-_105864247 4.26 ENST00000461719.1
immunoglobulin heavy joining 4
chr9_-_127937800 4.10 ENST00000373110.4
ENST00000314392.13
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
chr9_-_21994345 4.09 ENST00000579755.2
ENST00000530628.2
cyclin dependent kinase inhibitor 2A
chr2_+_231707650 4.04 ENST00000409321.5
prothymosin alpha
chr2_+_88885397 3.91 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr11_+_2902388 3.80 ENST00000380574.5
solute carrier family 22 member 18
chrX_+_154379433 3.67 ENST00000683627.1
emerin
chr16_+_85899121 3.66 ENST00000268638.10
ENST00000565552.1
interferon regulatory factor 8
chr10_+_5048748 3.56 ENST00000602997.5
ENST00000439082.7
aldo-keto reductase family 1 member C3
chrX_-_152753840 3.51 ENST00000617505.1
ENST00000684311.1
ENST00000617846.4
ENST00000595583.5
ENST00000620710.4
ENST00000611557.4
ENST00000623806.3
ENST00000623438.3
ENST00000598543.5
ENST00000611674.4
MAGE family member A2
chr3_-_114179052 3.48 ENST00000383673.5
ENST00000295881.9
dopamine receptor D3
chr3_-_183099464 3.47 ENST00000265594.9
methylcrotonoyl-CoA carboxylase 1
chr19_-_51372640 3.32 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr1_-_246566238 3.28 ENST00000366514.5
transcription factor B2, mitochondrial
chr17_-_47957824 3.20 ENST00000300557.3
proline rich 15 like
chr17_-_21042901 3.11 ENST00000261497.9
ubiquitin specific peptidase 22
chr11_-_64166102 3.10 ENST00000255681.7
ENST00000675777.1
mono-ADP ribosylhydrolase 1
chr2_+_237487239 3.05 ENST00000338530.8
ENST00000264605.8
ENST00000409373.5
melanophilin
chr11_-_57567617 3.02 ENST00000287156.9
ubiquitin conjugating enzyme E2 L6
chrX_+_154379203 3.02 ENST00000369835.3
ENST00000369842.9
emerin
chr14_+_75280078 2.97 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr14_-_106335613 2.92 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr19_-_51372269 2.89 ENST00000593572.5
ENST00000595157.1
natural killer cell granule protein 7
chr11_+_47215032 2.85 ENST00000622090.4
ENST00000378600.7
ENST00000378603.7
damage specific DNA binding protein 2
chr7_-_104207957 2.82 ENST00000447452.6
ENST00000297431.9
ENST00000626700.1
origin recognition complex subunit 5
chr1_-_3531403 2.78 ENST00000294599.8
multiple EGF like domains 6
chr1_-_151190125 2.78 ENST00000354473.4
ENST00000368892.9
ENST00000640458.1
vacuolar protein sorting 72 homolog
chr1_-_21783134 2.72 ENST00000308271.14
ubiquitin specific peptidase 48
chr18_+_58671439 2.70 ENST00000649217.2
MALT1 paracaspase
chr6_+_33620329 2.69 ENST00000374316.9
inositol 1,4,5-trisphosphate receptor type 3
chr5_-_111757549 2.67 ENST00000419114.6
neuronal regeneration related protein
chr19_-_8321354 2.67 ENST00000301457.3
NADH:ubiquinone oxidoreductase subunit A7
chrX_-_48919015 2.64 ENST00000376509.4
Pim-2 proto-oncogene, serine/threonine kinase
chr5_-_134226059 2.64 ENST00000519718.1
ENST00000481195.6
novel protein
protein phosphatase 2 catalytic subunit alpha
chr21_+_33266350 2.62 ENST00000290200.7
interleukin 10 receptor subunit beta
chr1_+_111227610 2.60 ENST00000369744.6
chitinase 3 like 2
chr9_-_21995262 2.59 ENST00000494262.5
cyclin dependent kinase inhibitor 2A
chrX_-_152733689 2.59 ENST00000370291.6
chondrosarcoma associated gene 1
chr5_-_151224069 2.58 ENST00000355417.7
coiled-coil domain containing 69
chr5_+_157731400 2.56 ENST00000231198.12
tRNA-histidine guanylyltransferase 1 like
chr11_-_28108109 2.54 ENST00000263181.7
kinesin family member 18A
chr1_+_111227699 2.54 ENST00000369748.9
chitinase 3 like 2
chr5_-_133026533 2.52 ENST00000509437.6
ENST00000355372.6
ENST00000513541.5
ENST00000509008.1
ENST00000513848.5
ENST00000504170.2
ENST00000324170.7
zinc finger CCHC-type containing 10
chr6_+_63572472 2.47 ENST00000370651.7
ENST00000626021.3
novel protein
protein tyrosine phosphatase 4A1
chr6_+_35297809 2.46 ENST00000316637.7
DEF6 guanine nucleotide exchange factor
chr9_+_110668854 2.46 ENST00000189978.10
ENST00000374440.7
muscle associated receptor tyrosine kinase
chr2_+_97713568 2.45 ENST00000264972.10
zeta chain of T cell receptor associated protein kinase 70
chr5_-_149551381 2.37 ENST00000670598.1
ENST00000657001.1
ENST00000515768.6
ENST00000261798.10
ENST00000377843.8
casein kinase 1 alpha 1
chr2_+_11556337 2.34 ENST00000234142.9
growth regulating estrogen receptor binding 1
chr9_-_101435760 2.30 ENST00000647789.2
ENST00000616752.1
aldolase, fructose-bisphosphate B
chr12_-_51028234 2.26 ENST00000547688.7
ENST00000394904.9
solute carrier family 11 member 2
chr12_+_93569814 2.21 ENST00000340600.6
suppressor of cytokine signaling 2
chr2_+_188291994 2.18 ENST00000409927.5
ENST00000409805.5
GULP PTB domain containing engulfment adaptor 1
chr17_-_5111836 2.17 ENST00000575898.5
zinc finger protein 232
chrX_-_120559889 2.16 ENST00000371323.3
cullin 4B
chr5_-_149551168 2.13 ENST00000515748.2
ENST00000606719.6
casein kinase 1 alpha 1
chrX_-_23884017 2.11 ENST00000633372.1
apolipoprotein O
chr5_-_111757382 2.10 ENST00000453526.6
ENST00000509427.5
neuronal regeneration related protein
chr5_-_111757704 1.99 ENST00000379671.7
neuronal regeneration related protein
chr20_+_36461303 1.97 ENST00000475894.5
DLG associated protein 4
chr11_+_31369834 1.97 ENST00000465995.6
DnaJ heat shock protein family (Hsp40) member C24
chr5_-_150289625 1.92 ENST00000683332.1
ENST00000398376.8
ENST00000672785.1
ENST00000672396.1
calcium/calmodulin dependent protein kinase II alpha
chr3_-_142578716 1.92 ENST00000661310.1
ENST00000350721.9
ATR serine/threonine kinase
chr12_-_32755876 1.90 ENST00000324868.13
tyrosyl-tRNA synthetase 2
chr12_+_5043873 1.89 ENST00000252321.5
potassium voltage-gated channel subfamily A member 5
chr15_+_59611776 1.89 ENST00000396065.3
ENST00000560585.5
glucosaminyl (N-acetyl) transferase 3, mucin type
chr4_+_169660062 1.86 ENST00000507875.5
ENST00000613795.4
chloride voltage-gated channel 3
chr2_+_232697299 1.85 ENST00000476995.5
ENST00000427233.5
ENST00000629305.2
ENST00000428883.5
ENST00000456491.5
ENST00000409480.5
ENST00000492910.5
ENST00000464402.5
ENST00000490612.5
ENST00000475359.6
ENST00000421433.5
ENST00000425040.5
ENST00000430720.5
ENST00000409547.5
ENST00000373563.9
ENST00000423659.5
ENST00000409196.7
ENST00000488734.5
ENST00000409451.7
ENST00000429187.5
ENST00000440945.5
GRB10 interacting GYF protein 2
chr17_-_42388360 1.84 ENST00000678960.1
ENST00000404395.3
ENST00000389272.7
ENST00000677421.1
ENST00000585517.5
ENST00000264657.10
ENST00000678048.1
ENST00000678674.1
ENST00000678913.1
ENST00000678572.1
ENST00000678906.1
signal transducer and activator of transcription 3
chr5_-_111758061 1.81 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
neuronal regeneration related protein
chr17_-_44218406 1.79 ENST00000526094.5
ENST00000529383.5
ENST00000530828.1
upstream binding transcription factor
chr16_+_1078781 1.79 ENST00000293897.5
somatostatin receptor 5
chrX_+_130401962 1.69 ENST00000305536.11
ENST00000370947.1
RNA binding motif protein X-linked 2
chr19_+_17267376 1.68 ENST00000447614.6
ENST00000359435.8
ENST00000599474.5
ENST00000599057.5
ENST00000598188.6
ENST00000601043.5
BRISC and BRCA1 A complex member 1
chr7_+_120273129 1.67 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr16_-_67159881 1.66 ENST00000345057.9
TNFRSF1A associated via death domain
chr13_+_52012375 1.64 ENST00000649708.2
ENST00000523764.1
ENST00000649340.2
ENST00000679544.1
ENST00000681053.1
ENST00000521508.2
ENST00000616513.1
ALG11 alpha-1,2-mannosyltransferase
chrX_+_106693838 1.62 ENST00000324342.7
ring finger protein 128
chr1_-_165445088 1.62 ENST00000359842.10
retinoid X receptor gamma
chr1_-_165445220 1.61 ENST00000619224.1
retinoid X receptor gamma
chr19_+_17267469 1.56 ENST00000596335.5
ENST00000601436.5
ENST00000595632.5
BRISC and BRCA1 A complex member 1
chr12_-_85836372 1.52 ENST00000361228.5
Ras association domain family member 9
chr19_-_51372686 1.50 ENST00000595217.1
natural killer cell granule protein 7
chr1_-_21783189 1.41 ENST00000400301.5
ENST00000532737.1
ubiquitin specific peptidase 48
chr2_+_191678122 1.32 ENST00000425611.9
ENST00000410026.7
nucleic acid binding protein 1
chr12_-_118359639 1.31 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr17_-_42388467 1.29 ENST00000678792.1
ENST00000679166.1
ENST00000677442.1
ENST00000677723.1
ENST00000678905.1
ENST00000677479.1
ENST00000678043.1
ENST00000677152.1
ENST00000677603.1
ENST00000588969.5
ENST00000678535.1
ENST00000679185.1
ENST00000677030.1
ENST00000679014.1
ENST00000678044.1
ENST00000678827.1
signal transducer and activator of transcription 3
chr6_-_24489565 1.23 ENST00000230036.2
glycosylphosphatidylinositol specific phospholipase D1
chr2_-_187513641 1.20 ENST00000392365.5
ENST00000435414.5
tissue factor pathway inhibitor
chr18_+_13277351 1.19 ENST00000679091.1
low density lipoprotein receptor class A domain containing 4
chr11_+_114400030 1.17 ENST00000540163.5
RNA binding motif protein 7
chrX_+_149881141 1.15 ENST00000535454.5
ENST00000542674.5
ENST00000286482.6
MAGE family member A8
chr7_-_27147774 1.12 ENST00000222728.3
homeobox A6
chr18_+_9475494 1.11 ENST00000383432.8
ralA binding protein 1
chr3_+_184315131 1.10 ENST00000427845.5
ENST00000342981.8
eukaryotic translation initiation factor 4 gamma 1
chr11_+_114400592 1.08 ENST00000541475.5
RNA binding motif protein 7
chr2_+_188291854 1.02 ENST00000409830.6
GULP PTB domain containing engulfment adaptor 1
chr22_+_23856703 0.96 ENST00000345044.10
solute carrier family 2 member 11
chr5_-_111757465 0.92 ENST00000446294.6
neuronal regeneration related protein
chr21_+_29299368 0.92 ENST00000399921.5
BTB domain and CNC homolog 1
chr2_-_55296361 0.86 ENST00000647547.1
coiled-coil domain containing 88A
chr2_+_210556590 0.83 ENST00000233072.10
ENST00000619804.1
carbamoyl-phosphate synthase 1
chr19_-_48752628 0.82 ENST00000645652.2
fucosyltransferase 1 (H blood group)
chr2_-_171433950 0.80 ENST00000375258.9
ENST00000442541.1
ENST00000392599.6
methyltransferase like 8
chr19_+_54630960 0.80 ENST00000396317.5
ENST00000396315.5
leukocyte immunoglobulin like receptor B1
chr16_+_70523782 0.76 ENST00000566095.6
ENST00000577085.1
ENST00000302516.10
ENST00000567654.1
splicing factor 3b subunit 3
chr13_+_27251545 0.74 ENST00000311549.11
ribosomal protein L21
chr18_+_9474994 0.73 ENST00000019317.8
ralA binding protein 1
chr1_-_84574407 0.72 ENST00000370630.6
chitobiase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 84.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
3.8 15.2 GO:0006175 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
3.5 10.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
3.2 39.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
2.8 19.9 GO:0030421 defecation(GO:0030421)
2.8 8.3 GO:0001923 B-1 B cell differentiation(GO:0001923)
2.7 15.9 GO:0015853 adenine transport(GO:0015853)
2.7 10.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
2.5 10.0 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
2.5 7.4 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
1.9 5.7 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
1.9 13.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
1.7 23.8 GO:0001522 pseudouridine synthesis(GO:0001522)
1.6 6.2 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
1.5 6.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
1.4 28.3 GO:0006527 arginine catabolic process(GO:0006527)
1.4 24.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
1.2 8.4 GO:0046618 drug export(GO:0046618)
1.2 3.6 GO:0016487 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
1.2 7.0 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
1.1 10.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.1 14.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.1 11.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
1.1 3.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.0 3.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
1.0 15.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
1.0 6.1 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.9 6.6 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.9 7.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.9 5.3 GO:0060356 leucine import(GO:0060356)
0.9 3.5 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.8 12.3 GO:0001778 plasma membrane repair(GO:0001778)
0.8 4.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.8 5.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.7 5.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.7 9.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.7 6.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.7 12.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.7 2.7 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.7 24.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.7 9.2 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.6 7.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.6 1.9 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.6 4.5 GO:0048478 replication fork protection(GO:0048478)
0.5 5.9 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.5 7.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.5 4.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.5 6.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.5 2.3 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 2.3 GO:0015692 lead ion transport(GO:0015692)
0.4 17.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.4 2.5 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.4 2.4 GO:0043366 beta selection(GO:0043366)
0.4 5.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.4 3.6 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.4 30.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.4 3.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.4 3.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.4 1.8 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.3 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 0.7 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 5.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 11.7 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.3 3.5 GO:0006552 leucine catabolic process(GO:0006552)
0.3 5.9 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.3 5.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.3 1.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.3 7.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3 49.6 GO:0002377 immunoglobulin production(GO:0002377)
0.3 7.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.3 0.8 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.3 1.9 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.3 15.0 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.2 2.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 18.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.6 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 1.7 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.2 2.0 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.2 0.5 GO:0099541 retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 2.1 GO:0042407 cristae formation(GO:0042407)
0.2 8.1 GO:0006270 DNA replication initiation(GO:0006270)
0.2 4.3 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.2 3.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 5.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 2.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.8 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 5.2 GO:0007140 male meiosis(GO:0007140)
0.1 3.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.7 GO:0045475 locomotor rhythm(GO:0045475)
0.1 5.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.4 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.1 3.1 GO:0016578 histone deubiquitination(GO:0016578)
0.1 4.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.2 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.8 GO:0061157 mRNA destabilization(GO:0061157)
0.1 3.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.8 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.4 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 2.8 GO:0043486 histone exchange(GO:0043486)
0.0 1.6 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 2.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 2.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.7 GO:0051923 sulfation(GO:0051923)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.5 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 1.3 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 2.1 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 3.6 GO:0060348 bone development(GO:0060348)
0.0 1.6 GO:0051289 protein homotetramerization(GO:0051289)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 79.2 GO:0005642 annulate lamellae(GO:0005642)
4.0 15.9 GO:0071817 MMXD complex(GO:0071817)
2.2 15.2 GO:0031415 NatA complex(GO:0031415)
1.9 13.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.7 8.3 GO:0032449 CBM complex(GO:0032449)
1.6 6.2 GO:0005715 late recombination nodule(GO:0005715)
1.5 10.5 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
1.5 11.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
1.4 4.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
1.1 6.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.1 9.8 GO:0031298 replication fork protection complex(GO:0031298)
0.7 4.3 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.7 5.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.6 6.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.6 6.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.6 36.7 GO:0005871 kinesin complex(GO:0005871)
0.6 7.4 GO:0030677 ribonuclease P complex(GO:0030677)
0.6 30.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.5 5.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5 2.3 GO:0070826 paraferritin complex(GO:0070826)
0.4 3.5 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.4 7.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.4 6.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 3.0 GO:0035976 AP1 complex(GO:0035976)
0.4 2.1 GO:0061617 MICOS complex(GO:0061617)
0.3 1.3 GO:0070876 SOSS complex(GO:0070876)
0.3 3.2 GO:0070552 BRISC complex(GO:0070552)
0.3 6.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 5.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 1.8 GO:1990635 proximal dendrite(GO:1990635)
0.3 2.8 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 31.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 25.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 3.1 GO:0000124 SAGA complex(GO:0000124)
0.2 4.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 28.9 GO:0000793 condensed chromosome(GO:0000793)
0.1 13.1 GO:0005901 caveola(GO:0005901)
0.1 2.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 2.6 GO:0051233 spindle midzone(GO:0051233)
0.1 5.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 4.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 2.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.7 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 5.2 GO:0031526 brush border membrane(GO:0031526)
0.1 1.7 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 2.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 5.0 GO:0005643 nuclear pore(GO:0005643)
0.1 31.6 GO:0000785 chromatin(GO:0000785)
0.1 1.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 6.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 15.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 3.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 8.9 GO:0005635 nuclear envelope(GO:0005635)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.9 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.8 GO:0001650 fibrillar center(GO:0001650)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.7 39.0 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
5.3 79.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
4.0 28.3 GO:0016403 dimethylargininase activity(GO:0016403)
4.0 15.9 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
3.8 15.2 GO:0004001 adenosine kinase activity(GO:0004001)
3.5 10.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
2.1 8.4 GO:0015307 drug:proton antiporter activity(GO:0015307)
2.1 10.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
2.0 6.1 GO:0098808 mRNA cap binding(GO:0098808)
2.0 23.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
1.8 5.3 GO:0004766 spermidine synthase activity(GO:0004766)
1.4 10.0 GO:0001849 complement component C1q binding(GO:0001849)
1.4 7.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
1.4 4.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
1.3 10.1 GO:0019237 centromeric DNA binding(GO:0019237)
1.2 3.6 GO:0047787 geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
1.1 15.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.8 40.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.8 3.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.8 7.0 GO:0089720 caspase binding(GO:0089720)
0.8 13.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.8 2.3 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.7 7.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.7 2.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.6 2.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.6 1.9 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.6 6.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.6 3.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.5 3.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5 5.9 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.5 7.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.5 2.6 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.5 30.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.5 3.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.5 8.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 1.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 10.0 GO:0008242 omega peptidase activity(GO:0008242)
0.5 2.3 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.4 6.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 3.5 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.4 1.6 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.4 5.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.4 7.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 5.2 GO:0019534 toxin transporter activity(GO:0019534)
0.4 6.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 1.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 5.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 3.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 52.3 GO:0003823 antigen binding(GO:0003823)
0.3 2.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.9 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.3 21.1 GO:0003777 microtubule motor activity(GO:0003777)
0.3 1.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 6.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 9.9 GO:0043236 laminin binding(GO:0043236)
0.2 11.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 1.9 GO:0032405 MutLalpha complex binding(GO:0032405)
0.2 1.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.8 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 1.2 GO:0004630 phospholipase D activity(GO:0004630)
0.2 6.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 3.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 13.8 GO:0019843 rRNA binding(GO:0019843)
0.2 2.6 GO:0050811 GABA receptor binding(GO:0050811)
0.2 4.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.5 GO:0015616 DNA translocase activity(GO:0015616)
0.2 5.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.4 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1 11.7 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 2.0 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.7 GO:0070513 death domain binding(GO:0070513)
0.1 19.9 GO:0008083 growth factor activity(GO:0008083)
0.1 1.9 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.6 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 5.0 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 7.1 GO:0019209 kinase activator activity(GO:0019209)
0.1 7.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 10.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 4.9 GO:0017022 myosin binding(GO:0017022)
0.1 4.3 GO:0019003 GDP binding(GO:0019003)
0.1 3.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.8 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 7.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 3.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.6 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 5.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 79.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.6 11.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 32.3 PID AURORA B PATHWAY Aurora B signaling
0.3 21.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 8.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 8.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 3.1 ST STAT3 PATHWAY STAT3 Pathway
0.2 9.0 PID ATR PATHWAY ATR signaling pathway
0.1 3.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 10.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 13.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 6.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 2.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 8.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 79.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
2.6 39.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
2.4 2.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.3 36.7 REACTOME KINESINS Genes involved in Kinesins
0.7 6.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.6 15.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.6 27.3 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.5 16.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.5 8.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.4 6.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.4 7.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.4 10.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.4 2.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3 8.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 2.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 5.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 6.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 7.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.2 7.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 6.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 1.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 6.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 11.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 5.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 3.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 25.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 8.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 5.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 3.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 2.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 3.3 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 3.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 3.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules